BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Date of publication	Date in BindingDB	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence 1	PDB ID(s) of Target Chain 1	UniProt (SwissProt) Recommended Name of Target Chain 1	UniProt (SwissProt) Entry Name of Target Chain 1	UniProt (SwissProt) Primary ID of Target Chain 1	UniProt (SwissProt) Secondary ID(s) of Target Chain 1	UniProt (SwissProt) Alternative ID(s) of Target Chain 1	UniProt (TrEMBL) Submitted Name of Target Chain 1	UniProt (TrEMBL) Entry Name of Target Chain 1	UniProt (TrEMBL) Primary ID of Target Chain 1	UniProt (TrEMBL) Secondary ID(s) of Target Chain 1	UniProt (TrEMBL) Alternative ID(s) of Target Chain 1	BindingDB Target Chain Sequence 2	PDB ID(s) of Target Chain 2	UniProt (SwissProt) Recommended Name of Target Chain 2	UniProt (SwissProt) Entry Name of Target Chain 2	UniProt (SwissProt) Primary ID of Target Chain 2	UniProt (SwissProt) Secondary ID(s) of Target Chain 2	UniProt (SwissProt) Alternative ID(s) of Target Chain 2	UniProt (TrEMBL) Submitted Name of Target Chain 2	UniProt (TrEMBL) Entry Name of Target Chain 2	UniProt (TrEMBL) Primary ID of Target Chain 2	UniProt (TrEMBL) Secondary ID(s) of Target Chain 2	UniProt (TrEMBL) Alternative ID(s) of Target Chain 2	BindingDB Target Chain Sequence 3	PDB ID(s) of Target Chain 3	UniProt (SwissProt) Recommended Name of Target Chain 3	UniProt (SwissProt) Entry Name of Target Chain 3	UniProt (SwissProt) Primary ID of Target Chain 3	UniProt (SwissProt) Secondary ID(s) of Target Chain 3	UniProt (SwissProt) Alternative ID(s) of Target Chain 3	UniProt (TrEMBL) Submitted Name of Target Chain 3	UniProt (TrEMBL) Entry Name of Target Chain 3	UniProt (TrEMBL) Primary ID of Target Chain 3	UniProt (TrEMBL) Secondary ID(s) of Target Chain 3	UniProt (TrEMBL) Alternative ID(s) of Target Chain 3	BindingDB Target Chain Sequence 4	PDB ID(s) of Target Chain 4	UniProt (SwissProt) Recommended Name of Target Chain 4	UniProt (SwissProt) Entry Name of Target Chain 4	UniProt (SwissProt) Primary ID of Target Chain 4	UniProt (SwissProt) Secondary ID(s) of Target Chain 4	UniProt (SwissProt) Alternative ID(s) of Target Chain 4	UniProt (TrEMBL) Submitted Name of Target Chain 4	UniProt (TrEMBL) Entry Name of Target Chain 4	UniProt (TrEMBL) Primary ID of Target Chain 4	UniProt (TrEMBL) Secondary ID(s) of Target Chain 4	UniProt (TrEMBL) Alternative ID(s) of Target Chain 4	BindingDB Target Chain Sequence 5	PDB ID(s) of Target Chain 5	UniProt (SwissProt) Recommended Name of Target Chain 5	UniProt (SwissProt) Entry Name of Target Chain 5	UniProt (SwissProt) Primary ID of Target Chain 5	UniProt (SwissProt) Secondary ID(s) of Target Chain 5	UniProt (SwissProt) Alternative ID(s) of Target Chain 5	UniProt (TrEMBL) Submitted Name of Target Chain 5	UniProt (TrEMBL) Entry Name of Target Chain 5	UniProt (TrEMBL) Primary ID of Target Chain 5	UniProt (TrEMBL) Secondary ID(s) of Target Chain 5	UniProt (TrEMBL) Alternative ID(s) of Target Chain 5	BindingDB Target Chain Sequence 6	PDB ID(s) of Target Chain 6	UniProt (SwissProt) Recommended Name of Target Chain 6	UniProt (SwissProt) Entry Name of Target Chain 6	UniProt (SwissProt) Primary ID of Target Chain 6	UniProt (SwissProt) Secondary ID(s) of Target Chain 6	UniProt (SwissProt) Alternative ID(s) of Target Chain 6	UniProt (TrEMBL) Submitted Name of Target Chain 6	UniProt (TrEMBL) Entry Name of Target Chain 6	UniProt (TrEMBL) Primary ID of Target Chain 6	UniProt (TrEMBL) Secondary ID(s) of Target Chain 6	UniProt (TrEMBL) Alternative ID(s) of Target Chain 6	BindingDB Target Chain Sequence 7	PDB ID(s) of Target Chain 7	UniProt (SwissProt) Recommended Name of Target Chain 7	UniProt (SwissProt) Entry Name of Target Chain 7	UniProt (SwissProt) Primary ID of Target Chain 7	UniProt (SwissProt) Secondary ID(s) of Target Chain 7	UniProt (SwissProt) Alternative ID(s) of Target Chain 7	UniProt (TrEMBL) Submitted Name of Target Chain 7	UniProt (TrEMBL) Entry Name of Target Chain 7	UniProt (TrEMBL) Primary ID of Target Chain 7	UniProt (TrEMBL) Secondary ID(s) of Target Chain 7	UniProt (TrEMBL) Alternative ID(s) of Target Chain 7	BindingDB Target Chain Sequence 8	PDB ID(s) of Target Chain 8	UniProt (SwissProt) Recommended Name of Target Chain 8	UniProt (SwissProt) Entry Name of Target Chain 8	UniProt (SwissProt) Primary ID of Target Chain 8	UniProt (SwissProt) Secondary ID(s) of Target Chain 8	UniProt (SwissProt) Alternative ID(s) of Target Chain 8	UniProt (TrEMBL) Submitted Name of Target Chain 8	UniProt (TrEMBL) Entry Name of Target Chain 8	UniProt (TrEMBL) Primary ID of Target Chain 8	UniProt (TrEMBL) Secondary ID(s) of Target Chain 8	UniProt (TrEMBL) Alternative ID(s) of Target Chain 8	BindingDB Target Chain Sequence 9	PDB ID(s) of Target Chain 9	UniProt (SwissProt) Recommended Name of Target Chain 9	UniProt (SwissProt) Entry Name of Target Chain 9	UniProt (SwissProt) Primary ID of Target Chain 9	UniProt (SwissProt) Secondary ID(s) of Target Chain 9	UniProt (SwissProt) Alternative ID(s) of Target Chain 9	UniProt (TrEMBL) Submitted Name of Target Chain 9	UniProt (TrEMBL) Entry Name of Target Chain 9	UniProt (TrEMBL) Primary ID of Target Chain 9	UniProt (TrEMBL) Secondary ID(s) of Target Chain 9	UniProt (TrEMBL) Alternative ID(s) of Target Chain 9	BindingDB Target Chain Sequence 10	PDB ID(s) of Target Chain 10	UniProt (SwissProt) Recommended Name of Target Chain 10	UniProt (SwissProt) Entry Name of Target Chain 10	UniProt (SwissProt) Primary ID of Target Chain 10	UniProt (SwissProt) Secondary ID(s) of Target Chain 10	UniProt (SwissProt) Alternative ID(s) of Target Chain 10	UniProt (TrEMBL) Submitted Name of Target Chain 10	UniProt (TrEMBL) Entry Name of Target Chain 10	UniProt (TrEMBL) Primary ID of Target Chain 10	UniProt (TrEMBL) Secondary ID(s) of Target Chain 10	UniProt (TrEMBL) Alternative ID(s) of Target Chain 10	BindingDB Target Chain Sequence 11	PDB ID(s) of Target Chain 11	UniProt (SwissProt) Recommended Name of Target Chain 11	UniProt (SwissProt) Entry Name of Target Chain 11	UniProt (SwissProt) Primary ID of Target Chain 11	UniProt (SwissProt) Secondary ID(s) of Target Chain 11	UniProt (SwissProt) Alternative ID(s) of Target Chain 11	UniProt (TrEMBL) Submitted Name of Target Chain 11	UniProt (TrEMBL) Entry Name of Target Chain 11	UniProt (TrEMBL) Primary ID of Target Chain 11	UniProt (TrEMBL) Secondary ID(s) of Target Chain 11	UniProt (TrEMBL) Alternative ID(s) of Target Chain 11	BindingDB Target Chain Sequence 12	PDB ID(s) of Target Chain 12	UniProt (SwissProt) Recommended Name of Target Chain 12	UniProt (SwissProt) Entry Name of Target Chain 12	UniProt (SwissProt) Primary ID of Target Chain 12	UniProt (SwissProt) Secondary ID(s) of Target Chain 12	UniProt (SwissProt) Alternative ID(s) of Target Chain 12	UniProt (TrEMBL) Submitted Name of Target Chain 12	UniProt (TrEMBL) Entry Name of Target Chain 12	UniProt (TrEMBL) Primary ID of Target Chain 12	UniProt (TrEMBL) Secondary ID(s) of Target Chain 12	UniProt (TrEMBL) Alternative ID(s) of Target Chain 12	BindingDB Target Chain Sequence 13	PDB ID(s) of Target Chain 13	UniProt (SwissProt) Recommended Name of Target Chain 13	UniProt (SwissProt) Entry Name of Target Chain 13	UniProt (SwissProt) Primary ID of Target Chain 13	UniProt (SwissProt) Secondary ID(s) of Target Chain 13	UniProt (SwissProt) Alternative ID(s) of Target Chain 13	UniProt (TrEMBL) Submitted Name of Target Chain 13	UniProt (TrEMBL) Entry Name of Target Chain 13	UniProt (TrEMBL) Primary ID of Target Chain 13	UniProt (TrEMBL) Secondary ID(s) of Target Chain 13	UniProt (TrEMBL) Alternative ID(s) of Target Chain 13	BindingDB Target Chain Sequence 14	PDB ID(s) of Target Chain 14	UniProt (SwissProt) Recommended Name of Target Chain 14	UniProt (SwissProt) Entry Name of Target Chain 14	UniProt (SwissProt) Primary ID of Target Chain 14	UniProt (SwissProt) Secondary ID(s) of Target Chain 14	UniProt (SwissProt) Alternative ID(s) of Target Chain 14	UniProt (TrEMBL) Submitted Name of Target Chain 14	UniProt (TrEMBL) Entry Name of Target Chain 14	UniProt (TrEMBL) Primary ID of Target Chain 14	UniProt (TrEMBL) Secondary ID(s) of Target Chain 14	UniProt (TrEMBL) Alternative ID(s) of Target Chain 14	BindingDB Target Chain Sequence 15	PDB ID(s) of Target Chain 15	UniProt (SwissProt) Recommended Name of Target Chain 15	UniProt (SwissProt) Entry Name of Target Chain 15	UniProt (SwissProt) Primary ID of Target Chain 15	UniProt (SwissProt) Secondary ID(s) of Target Chain 15	UniProt (SwissProt) Alternative ID(s) of Target Chain 15	UniProt (TrEMBL) Submitted Name of Target Chain 15	UniProt (TrEMBL) Entry Name of Target Chain 15	UniProt (TrEMBL) Primary ID of Target Chain 15	UniProt (TrEMBL) Secondary ID(s) of Target Chain 15	UniProt (TrEMBL) Alternative ID(s) of Target Chain 15	BindingDB Target Chain Sequence 16	PDB ID(s) of Target Chain 16	UniProt (SwissProt) Recommended Name of Target Chain 16	UniProt (SwissProt) Entry Name of Target Chain 16	UniProt (SwissProt) Primary ID of Target Chain 16	UniProt (SwissProt) Secondary ID(s) of Target Chain 16	UniProt (SwissProt) Alternative ID(s) of Target Chain 16	UniProt (TrEMBL) Submitted Name of Target Chain 16	UniProt (TrEMBL) Entry Name of Target Chain 16	UniProt (TrEMBL) Primary ID of Target Chain 16	UniProt (TrEMBL) Secondary ID(s) of Target Chain 16	UniProt (TrEMBL) Alternative ID(s) of Target Chain 16	BindingDB Target Chain Sequence 17	PDB ID(s) of Target Chain 17	UniProt (SwissProt) Recommended Name of Target Chain 17	UniProt (SwissProt) Entry Name of Target Chain 17	UniProt (SwissProt) Primary ID of Target Chain 17	UniProt (SwissProt) Secondary ID(s) of Target Chain 17	UniProt (SwissProt) Alternative ID(s) of Target Chain 17	UniProt (TrEMBL) Submitted Name of Target Chain 17	UniProt (TrEMBL) Entry Name of Target Chain 17	UniProt (TrEMBL) Primary ID of Target Chain 17	UniProt (TrEMBL) Secondary ID(s) of Target Chain 17	UniProt (TrEMBL) Alternative ID(s) of Target Chain 17	BindingDB Target Chain Sequence 18	PDB ID(s) of Target Chain 18	UniProt (SwissProt) Recommended Name of Target Chain 18	UniProt (SwissProt) Entry Name of Target Chain 18	UniProt (SwissProt) Primary ID of Target Chain 18	UniProt (SwissProt) Secondary ID(s) of Target Chain 18	UniProt (SwissProt) Alternative ID(s) of Target Chain 18	UniProt (TrEMBL) Submitted Name of Target Chain 18	UniProt (TrEMBL) Entry Name of Target Chain 18	UniProt (TrEMBL) Primary ID of Target Chain 18	UniProt (TrEMBL) Secondary ID(s) of Target Chain 18	UniProt (TrEMBL) Alternative ID(s) of Target Chain 18	BindingDB Target Chain Sequence 19	PDB ID(s) of Target Chain 19	UniProt (SwissProt) Recommended Name of Target Chain 19	UniProt (SwissProt) Entry Name of Target Chain 19	UniProt (SwissProt) Primary ID of Target Chain 19	UniProt (SwissProt) Secondary ID(s) of Target Chain 19	UniProt (SwissProt) Alternative ID(s) of Target Chain 19	UniProt (TrEMBL) Submitted Name of Target Chain 19	UniProt (TrEMBL) Entry Name of Target Chain 19	UniProt (TrEMBL) Primary ID of Target Chain 19	UniProt (TrEMBL) Secondary ID(s) of Target Chain 19	UniProt (TrEMBL) Alternative ID(s) of Target Chain 19	BindingDB Target Chain Sequence 20	PDB ID(s) of Target Chain 20	UniProt (SwissProt) Recommended Name of Target Chain 20	UniProt (SwissProt) Entry Name of Target Chain 20	UniProt (SwissProt) Primary ID of Target Chain 20	UniProt (SwissProt) Secondary ID(s) of Target Chain 20	UniProt (SwissProt) Alternative ID(s) of Target Chain 20	UniProt (TrEMBL) Submitted Name of Target Chain 20	UniProt (TrEMBL) Entry Name of Target Chain 20	UniProt (TrEMBL) Primary ID of Target Chain 20	UniProt (TrEMBL) Secondary ID(s) of Target Chain 20	UniProt (TrEMBL) Alternative ID(s) of Target Chain 20	BindingDB Target Chain Sequence 21	PDB ID(s) of Target Chain 21	UniProt (SwissProt) Recommended Name of Target Chain 21	UniProt (SwissProt) Entry Name of Target Chain 21	UniProt (SwissProt) Primary ID of Target Chain 21	UniProt (SwissProt) Secondary ID(s) of Target Chain 21	UniProt (SwissProt) Alternative ID(s) of Target Chain 21	UniProt (TrEMBL) Submitted Name of Target Chain 21	UniProt (TrEMBL) Entry Name of Target Chain 21	UniProt (TrEMBL) Primary ID of Target Chain 21	UniProt (TrEMBL) Secondary ID(s) of Target Chain 21	UniProt (TrEMBL) Alternative ID(s) of Target Chain 21	BindingDB Target Chain Sequence 22	PDB ID(s) of Target Chain 22	UniProt (SwissProt) Recommended Name of Target Chain 22	UniProt (SwissProt) Entry Name of Target Chain 22	UniProt (SwissProt) Primary ID of Target Chain 22	UniProt (SwissProt) Secondary ID(s) of Target Chain 22	UniProt (SwissProt) Alternative ID(s) of Target Chain 22	UniProt (TrEMBL) Submitted Name of Target Chain 22	UniProt (TrEMBL) Entry Name of Target Chain 22	UniProt (TrEMBL) Primary ID of Target Chain 22	UniProt (TrEMBL) Secondary ID(s) of Target Chain 22	UniProt (TrEMBL) Alternative ID(s) of Target Chain 22	BindingDB Target Chain Sequence 23	PDB ID(s) of Target Chain 23	UniProt (SwissProt) Recommended Name of Target Chain 23	UniProt (SwissProt) Entry Name of Target Chain 23	UniProt (SwissProt) Primary ID of Target Chain 23	UniProt (SwissProt) Secondary ID(s) of Target Chain 23	UniProt (SwissProt) Alternative ID(s) of Target Chain 23	UniProt (TrEMBL) Submitted Name of Target Chain 23	UniProt (TrEMBL) Entry Name of Target Chain 23	UniProt (TrEMBL) Primary ID of Target Chain 23	UniProt (TrEMBL) Secondary ID(s) of Target Chain 23	UniProt (TrEMBL) Alternative ID(s) of Target Chain 23	BindingDB Target Chain Sequence 24	PDB ID(s) of Target Chain 24	UniProt (SwissProt) Recommended Name of Target Chain 24	UniProt (SwissProt) Entry Name of Target Chain 24	UniProt (SwissProt) Primary ID of Target Chain 24	UniProt (SwissProt) Secondary ID(s) of Target Chain 24	UniProt (SwissProt) Alternative ID(s) of Target Chain 24	UniProt (TrEMBL) Submitted Name of Target Chain 24	UniProt (TrEMBL) Entry Name of Target Chain 24	UniProt (TrEMBL) Primary ID of Target Chain 24	UniProt (TrEMBL) Secondary ID(s) of Target Chain 24	UniProt (TrEMBL) Alternative ID(s) of Target Chain 24	BindingDB Target Chain Sequence 25	PDB ID(s) of Target Chain 25	UniProt (SwissProt) Recommended Name of Target Chain 25	UniProt (SwissProt) Entry Name of Target Chain 25	UniProt (SwissProt) Primary ID of Target Chain 25	UniProt (SwissProt) Secondary ID(s) of Target Chain 25	UniProt (SwissProt) Alternative ID(s) of Target Chain 25	UniProt (TrEMBL) Submitted Name of Target Chain 25	UniProt (TrEMBL) Entry Name of Target Chain 25	UniProt (TrEMBL) Primary ID of Target Chain 25	UniProt (TrEMBL) Secondary ID(s) of Target Chain 25	UniProt (TrEMBL) Alternative ID(s) of Target Chain 25	BindingDB Target Chain Sequence 26	PDB ID(s) of Target Chain 26	UniProt (SwissProt) Recommended Name of Target Chain 26	UniProt (SwissProt) Entry Name of Target Chain 26	UniProt (SwissProt) Primary ID of Target Chain 26	UniProt (SwissProt) Secondary ID(s) of Target Chain 26	UniProt (SwissProt) Alternative ID(s) of Target Chain 26	UniProt (TrEMBL) Submitted Name of Target Chain 26	UniProt (TrEMBL) Entry Name of Target Chain 26	UniProt (TrEMBL) Primary ID of Target Chain 26	UniProt (TrEMBL) Secondary ID(s) of Target Chain 26	UniProt (TrEMBL) Alternative ID(s) of Target Chain 26	BindingDB Target Chain Sequence 27	PDB ID(s) of Target Chain 27	UniProt (SwissProt) Recommended Name of Target Chain 27	UniProt (SwissProt) Entry Name of Target Chain 27	UniProt (SwissProt) Primary ID of Target Chain 27	UniProt (SwissProt) Secondary ID(s) of Target Chain 27	UniProt (SwissProt) Alternative ID(s) of Target Chain 27	UniProt (TrEMBL) Submitted Name of Target Chain 27	UniProt (TrEMBL) Entry Name of Target Chain 27	UniProt (TrEMBL) Primary ID of Target Chain 27	UniProt (TrEMBL) Secondary ID(s) of Target Chain 27	UniProt (TrEMBL) Alternative ID(s) of Target Chain 27	BindingDB Target Chain Sequence 28	PDB ID(s) of Target Chain 28	UniProt (SwissProt) Recommended Name of Target Chain 28	UniProt (SwissProt) Entry Name of Target Chain 28	UniProt (SwissProt) Primary ID of Target Chain 28	UniProt (SwissProt) Secondary ID(s) of Target Chain 28	UniProt (SwissProt) Alternative ID(s) of Target Chain 28	UniProt (TrEMBL) Submitted Name of Target Chain 28	UniProt (TrEMBL) Entry Name of Target Chain 28	UniProt (TrEMBL) Primary ID of Target Chain 28	UniProt (TrEMBL) Secondary ID(s) of Target Chain 28	UniProt (TrEMBL) Alternative ID(s) of Target Chain 28	BindingDB Target Chain Sequence 29	PDB ID(s) of Target Chain 29	UniProt (SwissProt) Recommended Name of Target Chain 29	UniProt (SwissProt) Entry Name of Target Chain 29	UniProt (SwissProt) Primary ID of Target Chain 29	UniProt (SwissProt) Secondary ID(s) of Target Chain 29	UniProt (SwissProt) Alternative ID(s) of Target Chain 29	UniProt (TrEMBL) Submitted Name of Target Chain 29	UniProt (TrEMBL) Entry Name of Target Chain 29	UniProt (TrEMBL) Primary ID of Target Chain 29	UniProt (TrEMBL) Secondary ID(s) of Target Chain 29	UniProt (TrEMBL) Alternative ID(s) of Target Chain 29	BindingDB Target Chain Sequence 30	PDB ID(s) of Target Chain 30	UniProt (SwissProt) Recommended Name of Target Chain 30	UniProt (SwissProt) Entry Name of Target Chain 30	UniProt (SwissProt) Primary ID of Target Chain 30	UniProt (SwissProt) Secondary ID(s) of Target Chain 30	UniProt (SwissProt) Alternative ID(s) of Target Chain 30	UniProt (TrEMBL) Submitted Name of Target Chain 30	UniProt (TrEMBL) Entry Name of Target Chain 30	UniProt (TrEMBL) Primary ID of Target Chain 30	UniProt (TrEMBL) Secondary ID(s) of Target Chain 30	UniProt (TrEMBL) Alternative ID(s) of Target Chain 30	BindingDB Target Chain Sequence 31	PDB ID(s) of Target Chain 31	UniProt (SwissProt) Recommended Name of Target Chain 31	UniProt (SwissProt) Entry Name of Target Chain 31	UniProt (SwissProt) Primary ID of Target Chain 31	UniProt (SwissProt) Secondary ID(s) of Target Chain 31	UniProt (SwissProt) Alternative ID(s) of Target Chain 31	UniProt (TrEMBL) Submitted Name of Target Chain 31	UniProt (TrEMBL) Entry Name of Target Chain 31	UniProt (TrEMBL) Primary ID of Target Chain 31	UniProt (TrEMBL) Secondary ID(s) of Target Chain 31	UniProt (TrEMBL) Alternative ID(s) of Target Chain 31	BindingDB Target Chain Sequence 32	PDB ID(s) of Target Chain 32	UniProt (SwissProt) Recommended Name of Target Chain 32	UniProt (SwissProt) Entry Name of Target Chain 32	UniProt (SwissProt) Primary ID of Target Chain 32	UniProt (SwissProt) Secondary ID(s) of Target Chain 32	UniProt (SwissProt) Alternative ID(s) of Target Chain 32	UniProt (TrEMBL) Submitted Name of Target Chain 32	UniProt (TrEMBL) Entry Name of Target Chain 32	UniProt (TrEMBL) Primary ID of Target Chain 32	UniProt (TrEMBL) Secondary ID(s) of Target Chain 32	UniProt (TrEMBL) Alternative ID(s) of Target Chain 32	BindingDB Target Chain Sequence 33	PDB ID(s) of Target Chain 33	UniProt (SwissProt) Recommended Name of Target Chain 33	UniProt (SwissProt) Entry Name of Target Chain 33	UniProt (SwissProt) Primary ID of Target Chain 33	UniProt (SwissProt) Secondary ID(s) of Target Chain 33	UniProt (SwissProt) Alternative ID(s) of Target Chain 33	UniProt (TrEMBL) Submitted Name of Target Chain 33	UniProt (TrEMBL) Entry Name of Target Chain 33	UniProt (TrEMBL) Primary ID of Target Chain 33	UniProt (TrEMBL) Secondary ID(s) of Target Chain 33	UniProt (TrEMBL) Alternative ID(s) of Target Chain 33	BindingDB Target Chain Sequence 34	PDB ID(s) of Target Chain 34	UniProt (SwissProt) Recommended Name of Target Chain 34	UniProt (SwissProt) Entry Name of Target Chain 34	UniProt (SwissProt) Primary ID of Target Chain 34	UniProt (SwissProt) Secondary ID(s) of Target Chain 34	UniProt (SwissProt) Alternative ID(s) of Target Chain 34	UniProt (TrEMBL) Submitted Name of Target Chain 34	UniProt (TrEMBL) Entry Name of Target Chain 34	UniProt (TrEMBL) Primary ID of Target Chain 34	UniProt (TrEMBL) Secondary ID(s) of Target Chain 34	UniProt (TrEMBL) Alternative ID(s) of Target Chain 34	BindingDB Target Chain Sequence 35	PDB ID(s) of Target Chain 35	UniProt (SwissProt) Recommended Name of Target Chain 35	UniProt (SwissProt) Entry Name of Target Chain 35	UniProt (SwissProt) Primary ID of Target Chain 35	UniProt (SwissProt) Secondary ID(s) of Target Chain 35	UniProt (SwissProt) Alternative ID(s) of Target Chain 35	UniProt (TrEMBL) Submitted Name of Target Chain 35	UniProt (TrEMBL) Entry Name of Target Chain 35	UniProt (TrEMBL) Primary ID of Target Chain 35	UniProt (TrEMBL) Secondary ID(s) of Target Chain 35	UniProt (TrEMBL) Alternative ID(s) of Target Chain 35	BindingDB Target Chain Sequence 36	PDB ID(s) of Target Chain 36	UniProt (SwissProt) Recommended Name of Target Chain 36	UniProt (SwissProt) Entry Name of Target Chain 36	UniProt (SwissProt) Primary ID of Target Chain 36	UniProt (SwissProt) Secondary ID(s) of Target Chain 36	UniProt (SwissProt) Alternative ID(s) of Target Chain 36	UniProt (TrEMBL) Submitted Name of Target Chain 36	UniProt (TrEMBL) Entry Name of Target Chain 36	UniProt (TrEMBL) Primary ID of Target Chain 36	UniProt (TrEMBL) Secondary ID(s) of Target Chain 36	UniProt (TrEMBL) Alternative ID(s) of Target Chain 36	BindingDB Target Chain Sequence 37	PDB ID(s) of Target Chain 37	UniProt (SwissProt) Recommended Name of Target Chain 37	UniProt (SwissProt) Entry Name of Target Chain 37	UniProt (SwissProt) Primary ID of Target Chain 37	UniProt (SwissProt) Secondary ID(s) of Target Chain 37	UniProt (SwissProt) Alternative ID(s) of Target Chain 37	UniProt (TrEMBL) Submitted Name of Target Chain 37	UniProt (TrEMBL) Entry Name of Target Chain 37	UniProt (TrEMBL) Primary ID of Target Chain 37	UniProt (TrEMBL) Secondary ID(s) of Target Chain 37	UniProt (TrEMBL) Alternative ID(s) of Target Chain 37	BindingDB Target Chain Sequence 38	PDB ID(s) of Target Chain 38	UniProt (SwissProt) Recommended Name of Target Chain 38	UniProt (SwissProt) Entry Name of Target Chain 38	UniProt (SwissProt) Primary ID of Target Chain 38	UniProt (SwissProt) Secondary ID(s) of Target Chain 38	UniProt (SwissProt) Alternative ID(s) of Target Chain 38	UniProt (TrEMBL) Submitted Name of Target Chain 38	UniProt (TrEMBL) Entry Name of Target Chain 38	UniProt (TrEMBL) Primary ID of Target Chain 38	UniProt (TrEMBL) Secondary ID(s) of Target Chain 38	UniProt (TrEMBL) Alternative ID(s) of Target Chain 38	BindingDB Target Chain Sequence 39	PDB ID(s) of Target Chain 39	UniProt (SwissProt) Recommended Name of Target Chain 39	UniProt (SwissProt) Entry Name of Target Chain 39	UniProt (SwissProt) Primary ID of Target Chain 39	UniProt (SwissProt) Secondary ID(s) of Target Chain 39	UniProt (SwissProt) Alternative ID(s) of Target Chain 39	UniProt (TrEMBL) Submitted Name of Target Chain 39	UniProt (TrEMBL) Entry Name of Target Chain 39	UniProt (TrEMBL) Primary ID of Target Chain 39	UniProt (TrEMBL) Secondary ID(s) of Target Chain 39	UniProt (TrEMBL) Alternative ID(s) of Target Chain 39	BindingDB Target Chain Sequence 40	PDB ID(s) of Target Chain 40	UniProt (SwissProt) Recommended Name of Target Chain 40	UniProt (SwissProt) Entry Name of Target Chain 40	UniProt (SwissProt) Primary ID of Target Chain 40	UniProt (SwissProt) Secondary ID(s) of Target Chain 40	UniProt (SwissProt) Alternative ID(s) of Target Chain 40	UniProt (TrEMBL) Submitted Name of Target Chain 40	UniProt (TrEMBL) Entry Name of Target Chain 40	UniProt (TrEMBL) Primary ID of Target Chain 40	UniProt (TrEMBL) Secondary ID(s) of Target Chain 40	UniProt (TrEMBL) Alternative ID(s) of Target Chain 40	BindingDB Target Chain Sequence 41	PDB ID(s) of Target Chain 41	UniProt (SwissProt) Recommended Name of Target Chain 41	UniProt (SwissProt) Entry Name of Target Chain 41	UniProt (SwissProt) Primary ID of Target Chain 41	UniProt (SwissProt) Secondary ID(s) of Target Chain 41	UniProt (SwissProt) Alternative ID(s) of Target Chain 41	UniProt (TrEMBL) Submitted Name of Target Chain 41	UniProt (TrEMBL) Entry Name of Target Chain 41	UniProt (TrEMBL) Primary ID of Target Chain 41	UniProt (TrEMBL) Secondary ID(s) of Target Chain 41	UniProt (TrEMBL) Alternative ID(s) of Target Chain 41	BindingDB Target Chain Sequence 42	PDB ID(s) of Target Chain 42	UniProt (SwissProt) Recommended Name of Target Chain 42	UniProt (SwissProt) Entry Name of Target Chain 42	UniProt (SwissProt) Primary ID of Target Chain 42	UniProt (SwissProt) Secondary ID(s) of Target Chain 42	UniProt (SwissProt) Alternative ID(s) of Target Chain 42	UniProt (TrEMBL) Submitted Name of Target Chain 42	UniProt (TrEMBL) Entry Name of Target Chain 42	UniProt (TrEMBL) Primary ID of Target Chain 42	UniProt (TrEMBL) Secondary ID(s) of Target Chain 42	UniProt (TrEMBL) Alternative ID(s) of Target Chain 42	BindingDB Target Chain Sequence 43	PDB ID(s) of Target Chain 43	UniProt (SwissProt) Recommended Name of Target Chain 43	UniProt (SwissProt) Entry Name of Target Chain 43	UniProt (SwissProt) Primary ID of Target Chain 43	UniProt (SwissProt) Secondary ID(s) of Target Chain 43	UniProt (SwissProt) Alternative ID(s) of Target Chain 43	UniProt (TrEMBL) Submitted Name of Target Chain 43	UniProt (TrEMBL) Entry Name of Target Chain 43	UniProt (TrEMBL) Primary ID of Target Chain 43	UniProt (TrEMBL) Secondary ID(s) of Target Chain 43	UniProt (TrEMBL) Alternative ID(s) of Target Chain 43	BindingDB Target Chain Sequence 44	PDB ID(s) of Target Chain 44	UniProt (SwissProt) Recommended Name of Target Chain 44	UniProt (SwissProt) Entry Name of Target Chain 44	UniProt (SwissProt) Primary ID of Target Chain 44	UniProt (SwissProt) Secondary ID(s) of Target Chain 44	UniProt (SwissProt) Alternative ID(s) of Target Chain 44	UniProt (TrEMBL) Submitted Name of Target Chain 44	UniProt (TrEMBL) Entry Name of Target Chain 44	UniProt (TrEMBL) Primary ID of Target Chain 44	UniProt (TrEMBL) Secondary ID(s) of Target Chain 44	UniProt (TrEMBL) Alternative ID(s) of Target Chain 44	BindingDB Target Chain Sequence 45	PDB ID(s) of Target Chain 45	UniProt (SwissProt) Recommended Name of Target Chain 45	UniProt (SwissProt) Entry Name of Target Chain 45	UniProt (SwissProt) Primary ID of Target Chain 45	UniProt (SwissProt) Secondary ID(s) of Target Chain 45	UniProt (SwissProt) Alternative ID(s) of Target Chain 45	UniProt (TrEMBL) Submitted Name of Target Chain 45	UniProt (TrEMBL) Entry Name of Target Chain 45	UniProt (TrEMBL) Primary ID of Target Chain 45	UniProt (TrEMBL) Secondary ID(s) of Target Chain 45	UniProt (TrEMBL) Alternative ID(s) of Target Chain 45	BindingDB Target Chain Sequence 46	PDB ID(s) of Target Chain 46	UniProt (SwissProt) Recommended Name of Target Chain 46	UniProt (SwissProt) Entry Name of Target Chain 46	UniProt (SwissProt) Primary ID of Target Chain 46	UniProt (SwissProt) Secondary ID(s) of Target Chain 46	UniProt (SwissProt) Alternative ID(s) of Target Chain 46	UniProt (TrEMBL) Submitted Name of Target Chain 46	UniProt (TrEMBL) Entry Name of Target Chain 46	UniProt (TrEMBL) Primary ID of Target Chain 46	UniProt (TrEMBL) Secondary ID(s) of Target Chain 46	UniProt (TrEMBL) Alternative ID(s) of Target Chain 46	BindingDB Target Chain Sequence 47	PDB ID(s) of Target Chain 47	UniProt (SwissProt) Recommended Name of Target Chain 47	UniProt (SwissProt) Entry Name of Target Chain 47	UniProt (SwissProt) Primary ID of Target Chain 47	UniProt (SwissProt) Secondary ID(s) of Target Chain 47	UniProt (SwissProt) Alternative ID(s) of Target Chain 47	UniProt (TrEMBL) Submitted Name of Target Chain 47	UniProt (TrEMBL) Entry Name of Target Chain 47	UniProt (TrEMBL) Primary ID of Target Chain 47	UniProt (TrEMBL) Secondary ID(s) of Target Chain 47	UniProt (TrEMBL) Alternative ID(s) of Target Chain 47	BindingDB Target Chain Sequence 48	PDB ID(s) of Target Chain 48	UniProt (SwissProt) Recommended Name of Target Chain 48	UniProt (SwissProt) Entry Name of Target Chain 48	UniProt (SwissProt) Primary ID of Target Chain 48	UniProt (SwissProt) Secondary ID(s) of Target Chain 48	UniProt (SwissProt) Alternative ID(s) of Target Chain 48	UniProt (TrEMBL) Submitted Name of Target Chain 48	UniProt (TrEMBL) Entry Name of Target Chain 48	UniProt (TrEMBL) Primary ID of Target Chain 48	UniProt (TrEMBL) Secondary ID(s) of Target Chain 48	UniProt (TrEMBL) Alternative ID(s) of Target Chain 48	BindingDB Target Chain Sequence 49	PDB ID(s) of Target Chain 49	UniProt (SwissProt) Recommended Name of Target Chain 49	UniProt (SwissProt) Entry Name of Target Chain 49	UniProt (SwissProt) Primary ID of Target Chain 49	UniProt (SwissProt) Secondary ID(s) of Target Chain 49	UniProt (SwissProt) Alternative ID(s) of Target Chain 49	UniProt (TrEMBL) Submitted Name of Target Chain 49	UniProt (TrEMBL) Entry Name of Target Chain 49	UniProt (TrEMBL) Primary ID of Target Chain 49	UniProt (TrEMBL) Secondary ID(s) of Target Chain 49	UniProt (TrEMBL) Alternative ID(s) of Target Chain 49	BindingDB Target Chain Sequence 50	PDB ID(s) of Target Chain 50	UniProt (SwissProt) Recommended Name of Target Chain 50	UniProt (SwissProt) Entry Name of Target Chain 50	UniProt (SwissProt) Primary ID of Target Chain 50	UniProt (SwissProt) Secondary ID(s) of Target Chain 50	UniProt (SwissProt) Alternative ID(s) of Target Chain 50	UniProt (TrEMBL) Submitted Name of Target Chain 50	UniProt (TrEMBL) Entry Name of Target Chain 50	UniProt (TrEMBL) Primary ID of Target Chain 50	UniProt (TrEMBL) Secondary ID(s) of Target Chain 50	UniProt (TrEMBL) Alternative ID(s) of Target Chain 50
38319	CN1CCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)CC1	InChI=1S/C21H27N7O2/c1-14-11-15(2)28(25-14)19-12-18(23-21(24-19)17-6-5-16(3)30-17)22-20(29)13-27-9-7-26(4)8-10-27/h5-6,11-12H,7-10,13H2,1-4H3,(H,22,23,24,29)	QIPISTDFCOPXCR-UHFFFAOYSA-N	21178	JMC511730 Compound 1::N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-(4-methylpiperazin-1-yl)acetamide::Pyrimidine analogue, 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 950							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21178	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21178&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768404	49689251							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38320	CN1CCCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)CC1	InChI=1S/C22H29N7O2/c1-15-12-16(2)29(26-15)20-13-19(24-22(25-20)18-7-6-17(3)31-18)23-21(30)14-28-9-5-8-27(4)10-11-28/h6-7,12-13H,5,8-11,14H2,1-4H3,(H,23,24,25,30)	NDSMOKBIZMIYDJ-UHFFFAOYSA-N	21193	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-(4-methyl-1,4-diazepan-1-yl)acetamide::Pyrimidin-4-ylacetamide, 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 285							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21193	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21193&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768415	49689266							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38321	CN(C)CC1CCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)CC1	InChI=1S/C24H33N7O2/c1-16-12-17(2)31(28-16)22-13-21(26-24(27-22)20-7-6-18(3)33-20)25-23(32)15-30-10-8-19(9-11-30)14-29(4)5/h6-7,12-13,19H,8-11,14-15H2,1-5H3,(H,25,26,27,32)	IRGVKZAWAFXJJG-UHFFFAOYSA-N	21196	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-{4-[(dimethylamino)methyl]piperidin-1-yl}acetamide::Pyrimidin-4-ylacetamide, 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1670							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21196	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21196&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768418	49689269							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38322	CN1CCC(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)CC1	InChI=1S/C22H28N6O2/c1-14-11-15(2)28(26-14)20-13-19(24-22(25-20)18-6-5-16(3)30-18)23-21(29)12-17-7-9-27(4)10-8-17/h5-6,11,13,17H,7-10,12H2,1-4H3,(H,23,24,25,29)	BKVXJUVJYOXVBD-UHFFFAOYSA-N	21201	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-(1-methylpiperidin-4-yl)acetamide::Pyrimidin-4-ylacetamide, 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4170							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21201	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21201&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768423	49689274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38323	CN(C)[C@H]1CCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)C1 |r|	InChI=1S/C22H29N7O2/c1-14-10-15(2)29(26-14)20-11-19(24-22(25-20)18-7-6-16(3)31-18)23-21(30)13-28-9-8-17(12-28)27(4)5/h6-7,10-11,17H,8-9,12-13H2,1-5H3,(H,23,24,25,30)	FJQPCZJPOCTEEK-UHFFFAOYSA-N	21203	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]acetamide::Pyrimidin-4-ylacetamide, 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 600							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21203	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21203&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768425	49689276							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38324	CCN[C@H]1CCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)C1 |r|	InChI=1S/C22H29N7O2/c1-5-23-17-8-9-28(12-17)13-21(30)24-19-11-20(29-15(3)10-14(2)27-29)26-22(25-19)18-7-6-16(4)31-18/h6-7,10-11,17,23H,5,8-9,12-13H2,1-4H3,(H,24,25,26,30)	KMMAIJQUGOQJIO-UHFFFAOYSA-N	21207	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-[(3S)-3-(ethylamino)pyrrolidin-1-yl]acetamide::Pyrimidin-4-ylacetamide, 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 420							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21207	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21207&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768429	49689280							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38325	CN(C)C[C@H]1CCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)C1 |r|	InChI=1S/C23H31N7O2/c1-15-10-16(2)30(27-15)21-11-20(25-23(26-21)19-7-6-17(3)32-19)24-22(31)14-29-9-8-18(13-29)12-28(4)5/h6-7,10-11,18H,8-9,12-14H2,1-5H3,(H,24,25,26,31)	UAAYMUFGVDVSAW-UHFFFAOYSA-N	21209	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-[(3R)-3-[(dimethylamino)methyl]pyrrolidin-1-yl]acetamide::Pyrimidin-4-ylacetamide, 23	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1860							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21209	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21209&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768431	49689282							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38326	CN(C)C[C@@H]1CCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)C1 |r|	InChI=1S/C23H31N7O2/c1-15-10-16(2)30(27-15)21-11-20(25-23(26-21)19-7-6-17(3)32-19)24-22(31)14-29-9-8-18(13-29)12-28(4)5/h6-7,10-11,18H,8-9,12-14H2,1-5H3,(H,24,25,26,31)	UAAYMUFGVDVSAW-UHFFFAOYSA-N	21210	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-[(3S)-3-[(dimethylamino)methyl]pyrrolidin-1-yl]acetamide::Pyrimidin-4-ylacetamide, 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1010							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21210	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21210&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768432	49689283							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38327	CN(C)CCC(=O)Nc1cc(nc(n1)-c1ccc(C)o1)-n1nc(C)cc1C	InChI=1S/C19H24N6O2/c1-12-10-13(2)25(23-12)17-11-16(20-18(26)8-9-24(4)5)21-19(22-17)15-7-6-14(3)27-15/h6-7,10-11H,8-9H2,1-5H3,(H,20,21,22,26)	AACWUFIIMOHGSO-UHFFFAOYSA-N	21211	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-3-(dimethylamino)propanamide::Pyrimidin-4-ylacetamide, 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 650							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21211	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21211&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768433	49689284							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
38328	CN(C)[C@H]1CCN(CCC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)C1 |r|	InChI=1S/C23H31N7O2/c1-15-12-16(2)30(27-15)21-13-20(25-23(26-21)19-7-6-17(3)32-19)24-22(31)9-11-29-10-8-18(14-29)28(4)5/h6-7,12-13,18H,8-11,14H2,1-5H3,(H,24,25,26,31)	FVYCZVOQAJZLBF-UHFFFAOYSA-N	21212	N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-3-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]propanamide::Pyrimidin-4-ylacetamide, 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2280							Curated from the literature by BindingDB	10.1021/jm701187w	10.7270/Q2RF5S9C	18307293	aid1798055		Slee, DH; Moorjani, M; Zhang, X; Lin, E; Lanier, MC; Chen, Y; Rueter, JK; Lechner, SM; Markison, S; Malany, S; Joswig, T; Santos, M; Gross, RS; Williams, JP; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Wen, J; O'Brien, Z; Petroski, R; Saunders, J	3/27/2008	4/7/2008	Neuroscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21212	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21212&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24768434	49689285							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43840	CN(C1CCNCC1)C(=O)N1CC(=C[C@H]1c1ccccc1)c1cc(F)ccc1F |c:13|	InChI=1S/C23H25F2N3O/c1-27(19-9-11-26-12-10-19)23(29)28-15-17(20-14-18(24)7-8-21(20)25)13-22(28)16-5-3-2-4-6-16/h2-8,13-14,19,22,26H,9-12,15H2,1H3	NKLVBHMAIMEVEH-UHFFFAOYSA-N	24054	(2S)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-N-(piperidin-4-yl)-2,5-dihydro-1H-pyrrole-1-carboxamide::dihydropyrrole, 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1300					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24054&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11675645	53786051			DB08239				1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43841	[H][C@]1(C=C(CN1C(=O)N(C)C1CCN(CC1)C(C)=O)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C25H27F2N3O2/c1-17(31)29-12-10-21(11-13-29)28(2)25(32)30-16-19(22-15-20(26)8-9-23(22)27)14-24(30)18-6-4-3-5-7-18/h3-9,14-15,21,24H,10-13,16H2,1-2H3	OYCCHVFLJCOTKI-UHFFFAOYSA-N	24055	(2S)-4-(2,5-difluorophenyl)-N-(1-acetylpiperidin-4-yl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide::CHEMBL208422::dihydropyrrole, 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24055&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901491	53786052		CHEMBL208422					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43842	[H][C@]1(C=C(CN1C(=O)N(C)CCCN)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C21H23F2N3O/c1-25(11-5-10-24)21(27)26-14-16(18-13-17(22)8-9-19(18)23)12-20(26)15-6-3-2-4-7-15/h2-4,6-9,12-13,20H,5,10-11,14,24H2,1H3	QRNZXNUHQIYSQV-UHFFFAOYSA-N	24056	(2S)-N-(3-aminopropyl)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide::CHEMBL382587::dihydropyrrole, 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1300					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24056&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901492	53786053		CHEMBL382587					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43843	[H][C@]1(C=C(CN1C(=O)C(C)(C)CN)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C21H22F2N2O/c1-21(2,13-24)20(26)25-12-15(17-11-16(22)8-9-18(17)23)10-19(25)14-6-4-3-5-7-14/h3-11,19H,12-13,24H2,1-2H3	ZPUWHZPEHISDSA-UHFFFAOYSA-N	24057	CHEMBL203045::3-amino-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]-2,2-dimethylpropan-1-one::dihydropyrrole, 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2200					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24057&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901493	53786054		CHEMBL203045					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43844	[H][C@]1(C=C(CN1C(=O)[C@@H](N)C(C)C)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C21H22F2N2O/c1-13(2)20(24)21(26)25-12-15(17-11-16(22)8-9-18(17)23)10-19(25)14-6-4-3-5-7-14/h3-11,13,19-20H,12,24H2,1-2H3	GNFWJCGIZJCASB-UHFFFAOYSA-N	24058	(2S)-2-amino-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]-3-methylbutan-1-one::dihydropyrrole, 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2400					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24058&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901494	53786055							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43845	N[C@@H](C1CC1)C(=O)N1CC(=C[C@H]1c1ccccc1)c1cc(F)ccc1F |c:10|	InChI=1S/C21H20F2N2O/c22-16-8-9-18(23)17(11-16)15-10-19(13-4-2-1-3-5-13)25(12-15)21(26)20(24)14-6-7-14/h1-5,8-11,14,19-20H,6-7,12,24H2	VCOUEHUEFUDZIS-UHFFFAOYSA-N	24060	(2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]ethan-1-one::CHEMBL204459::dihydropyrrole, 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3500					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24060&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			6102824	53786057		CHEMBL204459	DB08244				1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43846	[H][C@]1(C=C(CN1C(=O)[C@@H](N)C(C)(C)C)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C22H24F2N2O/c1-22(2,3)20(25)21(27)26-13-15(17-12-16(23)9-10-18(17)24)11-19(26)14-7-5-4-6-8-14/h4-12,19-20H,13,25H2,1-3H3	SGSKDJMEPQTYQW-UHFFFAOYSA-N	24061	(2S)-2-amino-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]-3,3-dimethylbutan-1-one::dihydropyrrole, 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1500					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24061&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901496	53786058							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43847	[H][C@]1(C=C(CN1C(=O)[C@@H](NC(=O)OCCO)C(C)(C)C)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C25H28F2N2O4/c1-25(2,3)22(28-24(32)33-12-11-30)23(31)29-15-17(19-14-18(26)9-10-20(19)27)13-21(29)16-7-5-4-6-8-16/h4-10,13-14,21-22,30H,11-12,15H2,1-3H3,(H,28,32)	RWUSOKGVCNRFRC-UHFFFAOYSA-N	24062	CHEMBL202788::2-hydroxyethyl N-[(2S)-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate::dihydropyrrole, 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24062&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			15950258	53786059		CHEMBL202788					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43848	[H][C@]1(C=C(CN1C(=O)[C@@H](O)C1CC1)c1cc(F)ccc1F)c1ccccc1 |r,c:2|	InChI=1S/C21H19F2NO2/c22-16-8-9-18(23)17(11-16)15-10-19(13-4-2-1-3-5-13)24(12-15)21(26)20(25)14-6-7-14/h1-5,8-11,14,19-20,25H,6-7,12H2	FHIRATRLDJRXHH-UHFFFAOYSA-N	24063	CHEMBL382165::(2S)-2-cyclopropyl-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]-2-hydroxyethan-1-one::dihydropyrrole, 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.01.030	10.7270/Q27W69HG	16439123	aid1798395		Fraley, ME; Garbaccio, RM; Arrington, KL; Hoffman, WF; Tasber, ES; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Fernandes, C; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Yan, Y; Kuo, LC; Prueksaritanont, T; Shu, C; Torrent, M; Heimbrook, DC; Kohl, NE; Huber, HE; Hartman, GD	4/1/2006	8/4/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24063&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901497	53786060		CHEMBL382165					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43874	CC(=O)N1N=C(C[C@H]1c1cccc(O)c1)c1cc(F)ccc1F |r,c:4|	InChI=1S/C17H14F2N2O2/c1-10(22)21-17(11-3-2-4-13(23)7-11)9-16(20-21)14-8-12(18)5-6-15(14)19/h2-8,17,23H,9H2,1H3	YLSHULIHKQRKEM-UHFFFAOYSA-N	24065	CHEMBL195232::1-[(5S)-3-(2,5-difluorophenyl)-5-(3-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one::3,5-diaryl-4,5-dihydropyrazole, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26.4					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.03.040	10.7270/Q2445JTH	16603356	aid1798397		Cox, CD; Torrent, M; Breslin, MJ; Mariano, BJ; Whitman, DB; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Kohl, NE; Yan, Y; Kuo, LC; Prueksaritanont, T; Slaughter, DE; Li, C; Mahan, E; Lu, B; Hartman, GD	6/15/2006	8/1/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24065	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24065&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901498	53786062		CHEMBL195232					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43875	CN(C)C(=O)N1N=C(C[C@@]1(CCCN)c1ccccc1)c1cc(F)ccc1F |r,c:6|	InChI=1S/C21H24F2N4O/c1-26(2)20(28)27-21(11-6-12-24,15-7-4-3-5-8-15)14-19(25-27)17-13-16(22)9-10-18(17)23/h3-5,7-10,13H,6,11-12,14,24H2,1-2H3	OHLDJJXRTLZQSU-UHFFFAOYSA-N	24089	(5S)-5-(3-aminopropyl)-3-(2,5-difluorophenyl)-N,N-dimethyl-5-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamide::CHEMBL377566::3,5-diaryl-4,5-dihydropyrazole, 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 19.3					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2006.03.040	10.7270/Q2445JTH	16603356	aid1798397		Cox, CD; Torrent, M; Breslin, MJ; Mariano, BJ; Whitman, DB; Coleman, PJ; Buser, CA; Walsh, ES; Hamilton, K; Schaber, MD; Lobell, RB; Tao, W; South, VJ; Kohl, NE; Yan, Y; Kuo, LC; Prueksaritanont, T; Slaughter, DE; Li, C; Mahan, E; Lu, B; Hartman, GD	6/15/2006	8/1/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24089	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24089&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			15604796	53786086		CHEMBL377566					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43891	CN(C)CCC[C@]1(CN(N=C1C(C)=O)c1cc(C)ccc1F)c1ccccc1 |r,c:9|	InChI=1S/C23H28FN3O/c1-17-11-12-20(24)21(15-17)27-16-23(13-8-14-26(3)4,22(25-27)18(2)28)19-9-6-5-7-10-19/h5-7,9-12,15H,8,13-14,16H2,1-4H3	FTEPMVFWUZEGMB-UHFFFAOYSA-N	24103	1-[(4R)-4-[3-(dimethylamino)propyl]-1-(2-fluoro-5-methylphenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-3-yl]ethan-1-one::1,4-diaryl-4,5-dihydropyrazole, 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3036					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.07.074	10.7270/Q20C4T36	17766111	aid1798399		Roecker, AJ; Coleman, PJ; Mercer, SP; Schreier, JD; Buser, CA; Walsh, ES; Hamilton, K; Lobell, RB; Tao, W; Diehl, RE; South, VJ; Davide, JP; Kohl, NE; Yan, Y; Kuo, LC; Li, C; Fernandez-Metzler, C; Mahan, EA; Prueksaritanont, T; Hartman, GD	10/15/2007	8/1/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24103	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24103&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11509189	53786100							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
43892	CC(=O)N1CCN(CCC[C@]2([C@@H]3COc4ccc(F)cc4N3N=C2C(C)=O)c2ccccc2)CC1 |r,c:24|	InChI=1S/C27H31FN4O3/c1-19(33)26-27(21-7-4-3-5-8-21,11-6-12-30-13-15-31(16-14-30)20(2)34)25-18-35-24-10-9-22(28)17-23(24)32(25)29-26/h3-5,7-10,17,25H,6,11-16,18H2,1-2H3	BWKAHABETZLDBG-UHFFFAOYSA-N	24104	1-[(5R,6R)-5-[3-(4-acetylpiperazin-1-yl)propyl]-12-fluoro-5-phenyl-8-oxa-2,3-diazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,10,12-tetraen-4-yl]ethan-1-one::CHEMBL250125::dihydropyrazolobenzoxazine, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.07.074	10.7270/Q20C4T36	17766111	aid1798399		Roecker, AJ; Coleman, PJ; Mercer, SP; Schreier, JD; Buser, CA; Walsh, ES; Hamilton, K; Lobell, RB; Tao, W; Diehl, RE; South, VJ; Davide, JP; Kohl, NE; Yan, Y; Kuo, LC; Li, C; Fernandez-Metzler, C; Mahan, EA; Prueksaritanont, T; Hartman, GD	10/15/2007	8/1/2008	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24104	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24104&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11662966	53786101		CHEMBL250125					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44012	C(Cc1ccc(Oc2nc3ccccc3s2)cc1)N1CCCCC1	InChI=1S/C20H22N2OS/c1-4-13-22(14-5-1)15-12-16-8-10-17(11-9-16)23-20-21-18-6-2-3-7-19(18)24-20/h2-3,6-11H,1,4-5,12-15H2	DHHMVJVCMLXZBO-UHFFFAOYSA-N	24223	2-{4-[2-(piperidin-1-yl)ethyl]phenoxy}-1,3-benzothiazole::Benzthiazole compound, 27b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24223	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24223&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11427736	53786220							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44013	OC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C20H22N2O2S/c23-16-10-13-22(14-11-16)12-9-15-5-7-17(8-6-15)24-20-21-18-3-1-2-4-19(18)25-20/h1-8,16,23H,9-14H2	HHJAPVOVRQGCFN-UHFFFAOYSA-N	24224	1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-ol::Benzthiazole compound, 27e	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24224	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24224&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11416924	53786221							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44014	C(CN1CCCCC1)Oc1ccc(Oc2nc3ccccc3o2)cc1	InChI=1S/C20H22N2O3/c1-4-12-22(13-5-1)14-15-23-16-8-10-17(11-9-16)24-20-21-18-6-2-3-7-19(18)25-20/h2-3,6-11H,1,4-5,12-15H2	ZIQGASWXUSSORV-UHFFFAOYSA-N	24203	2-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1,3-benzoxazole::Benzoxazole compound, 10b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24203	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24203&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11739248	53786200							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44031	O=C1CCCN1C1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C24H27N3O2S/c28-23-6-3-14-27(23)19-12-16-26(17-13-19)15-11-18-7-9-20(10-8-18)29-24-25-21-4-1-2-5-22(21)30-24/h1-2,4-5,7-10,19H,3,6,11-17H2	GIYCUMSDCASBAI-UHFFFAOYSA-N	24227	1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)pyrrolidin-2-one::Benzthiazole compound, 27j	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24227	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24227&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11189372	53786224							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44032	O=C1OCCN1C1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C23H25N3O3S/c27-23-26(15-16-28-23)18-10-13-25(14-11-18)12-9-17-5-7-19(8-6-17)29-22-24-20-3-1-2-4-21(20)30-22/h1-8,18H,9-16H2	RUPCCWFCAYKMFK-UHFFFAOYSA-N	24228	3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)-1,3-oxazolidin-2-one::Benzthiazole compound, 27l	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 500							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24228	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24228&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901587	53786225							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44033	CC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C22H25N3O2S/c1-16(26)23-18-11-14-25(15-12-18)13-10-17-6-8-19(9-7-17)27-22-24-20-4-2-3-5-21(20)28-22/h2-9,18H,10-15H2,1H3,(H,23,26)	PSVCSILLBNBXNX-UHFFFAOYSA-N	24229	N-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)acetamide::Benzthiazole compound, 27n	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24229	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24229&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901588	53786226							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44034	CC(=O)OCC(=O)NC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C24H27N3O4S/c1-17(28)30-16-23(29)25-19-11-14-27(15-12-19)13-10-18-6-8-20(9-7-18)31-24-26-21-4-2-3-5-22(21)32-24/h2-9,19H,10-16H2,1H3,(H,25,29)	UNNDDWDUVLBXRL-UHFFFAOYSA-N	24230	[(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)carbamoyl]methyl acetate::Benzthiazole compound, 27o	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24230	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24230&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901589	53786227							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44035	C(N1CCCCC1)c1ccc(Oc2nc3ccccc3s2)cc1	InChI=1S/C19H20N2OS/c1-4-12-21(13-5-1)14-15-8-10-16(11-9-15)22-19-20-17-6-2-3-7-18(17)23-19/h2-3,6-11H,1,4-5,12-14H2	JNKRNJIZLGLIJG-UHFFFAOYSA-N	24231	2-[4-(piperidin-1-ylmethyl)phenoxy]-1,3-benzothiazole::Benzthiazole compound, 33b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24231	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24231&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11472798	53786228							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44036	OC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C19H20N2O2S/c22-15-9-11-21(12-10-15)13-14-5-7-16(8-6-14)23-19-20-17-3-1-2-4-18(17)24-19/h1-8,15,22H,9-13H2	CFTXJKKITUELKJ-UHFFFAOYSA-N	24232	1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-ol::Benzthiazole compound, 33e	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24232	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24232&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11473281	53786229							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44037	NC(=O)C1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C20H21N3O2S/c21-19(24)15-9-11-23(12-10-15)13-14-5-7-16(8-6-14)25-20-22-17-3-1-2-4-18(17)26-20/h1-8,15H,9-13H2,(H2,21,24)	MPIXODNJTUZDGF-UHFFFAOYSA-N	24233	1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidine-4-carboxamide::Benzthiazole compound, 33h	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24233	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24233&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901590	53786230							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44038	O=C1CCCN1C1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C23H25N3O2S/c27-22-6-3-13-26(22)18-11-14-25(15-12-18)16-17-7-9-19(10-8-17)28-23-24-20-4-1-2-5-21(20)29-23/h1-2,4-5,7-10,18H,3,6,11-16H2	UBVVZACYWWPTID-UHFFFAOYSA-N	24234	1-(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-yl)pyrrolidin-2-one::Benzthiazole compound, 33j	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24234	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24234&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11223519	53786231							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44039	O=C1OCCN1C1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C22H23N3O3S/c26-22-25(13-14-27-22)17-9-11-24(12-10-17)15-16-5-7-18(8-6-16)28-21-23-19-3-1-2-4-20(19)29-21/h1-8,17H,9-15H2	MOWJCGXXGLULBX-UHFFFAOYSA-N	24235	3-(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-yl)-1,3-oxazolidin-2-one::Benzthiazole compound, 33l	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 24000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24235	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24235&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11315811	53786232							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44040	CC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C21H23N3O2S/c1-15(25)22-17-10-12-24(13-11-17)14-16-6-8-18(9-7-16)26-21-23-19-4-2-3-5-20(19)27-21/h2-9,17H,10-14H2,1H3,(H,22,25)	UVZMEOGKJYOCNE-UHFFFAOYSA-N	24236	N-(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-yl)acetamide::Benzthiazole compound, 33n	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24236	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24236&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901591	53786233							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44041	CC(=O)OCC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C23H25N3O4S/c1-16(27)29-15-22(28)24-18-10-12-26(13-11-18)14-17-6-8-19(9-7-17)30-23-25-20-4-2-3-5-21(20)31-23/h2-9,18H,10-15H2,1H3,(H,24,28)	GACNDIIZOZQWCU-UHFFFAOYSA-N	24237	[(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-yl)carbamoyl]methyl acetate::Benzthiazole compound, 33o	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24237&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901592	53786234							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44042	OCC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C21H23N3O3S/c25-14-20(26)22-16-9-11-24(12-10-16)13-15-5-7-17(8-6-15)27-21-23-18-3-1-2-4-19(18)28-21/h1-8,16,25H,9-14H2,(H,22,26)	IJHSPFFWIXGDBB-UHFFFAOYSA-N	24238	N-(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-yl)-2-hydroxyacetamide::Benzthiazole compound, 33p	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>16000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24238	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24238&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11200344	53786235							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44043	c1ccc2c(c1)nc(s2)Oc3ccc(cc3)CN4CCC(CC4)C(=O)O	InChI=1S/C20H20N2O3S/c23-19(24)15-9-11-22(12-10-15)13-14-5-7-16(8-6-14)25-20-21-17-3-1-2-4-18(17)26-20/h1-8,15H,9-13H2,(H,23,24)	BUZBVOKDNAZIIM-UHFFFAOYSA-N	24239	1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidine-4-carboxylic acid::Benzthiazole compound, 33r	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798406		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24239	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24239&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	BGW	6ENC	11245596	53786236							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44044	OC1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C20H22N2O3S/c23-15-9-11-22(12-10-15)13-14-24-16-5-7-17(8-6-16)25-20-21-18-3-1-2-4-19(18)26-20/h1-8,15,23H,9-14H2	QEEKSUQXDWTJIW-UHFFFAOYSA-N	24213	1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}piperidin-4-ol::Benzthiazole compound, 11e	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000						25.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798405		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24213	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24213&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11303210	53786210							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44045	OCC1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C21H24N2O3S/c24-15-16-9-11-23(12-10-16)13-14-25-17-5-7-18(8-6-17)26-21-22-19-3-1-2-4-20(19)27-21/h1-8,16,24H,9-15H2	NTOXQUBAGYBHEG-UHFFFAOYSA-N	24215	(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}piperidin-4-yl)methanol::Benzthiazole compound, 11f	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3600						25.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798405		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24215	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24215&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11211303	53786212							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44046	O=C1CCCN1C1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C24H27N3O3S/c28-23-6-3-13-27(23)18-11-14-26(15-12-18)16-17-29-19-7-9-20(10-8-19)30-24-25-21-4-1-2-5-22(21)31-24/h1-2,4-5,7-10,18H,3,6,11-17H2	OAUXHFPOFOZZLZ-UHFFFAOYSA-N	24220	1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}piperidin-4-yl)pyrrolidin-2-one::Benzthiazole compound, 11j	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700						25.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798405		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24220	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24220&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11201443	53786217							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44047	O=C1CCCCN1C1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C25H29N3O3S/c29-24-7-3-4-14-28(24)19-12-15-27(16-13-19)17-18-30-20-8-10-21(11-9-20)31-25-26-22-5-1-2-6-23(22)32-25/h1-2,5-6,8-11,19H,3-4,7,12-18H2	PCDBONUTTZAAAS-UHFFFAOYSA-N	24221	1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}piperidin-4-yl)piperidin-2-one::Benzthiazole compound, 11k	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1800						25.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798405		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24221	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24221&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11328449	53786218							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
44048	O=C1OCCN1C1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1	InChI=1S/C23H25N3O4S/c27-23-26(14-16-29-23)17-9-11-25(12-10-17)13-15-28-18-5-7-19(8-6-18)30-22-24-20-3-1-2-4-21(20)31-22/h1-8,17H,9-16H2	WJHNHOUMKXMLGR-UHFFFAOYSA-N	24222	3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}piperidin-4-yl)-1,3-oxazolidin-2-one::Benzthiazole compound, 11l	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700						25.00 C	Curated from the literature by BindingDB	10.1021/jm701575k	10.7270/Q2GB22CX	18588282	aid1798405		Grice, CA; Tays, KL; Savall, BM; Wei, J; Butler, CR; Axe, FU; Bembenek, SD; Fourie, AM; Dunford, PJ; Lundeen, K; Coles, F; Xue, X; Riley, JP; Williams, KN; Karlsson, L; Edwards, JP	7/24/2008	9/14/2008	Johnson & Johnson Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24222	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24222&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24901586	53786219							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54579	CC(C)NCc1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl	InChI=1S/C20H20Cl3N3/c1-12(2)24-11-18-13(3)20(14-4-6-15(21)7-5-14)26(25-18)19-9-8-16(22)10-17(19)23/h4-10,12,24H,11H2,1-3H3	XZEWWPFRVAGHEH-UHFFFAOYSA-N	29960	arylpyrazole, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29960&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143406	85147724							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54580	Cc1c(CNC2CCCC2)nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl	InChI=1S/C22H22Cl3N3/c1-14-20(13-26-18-4-2-3-5-18)27-28(21-11-10-17(24)12-19(21)25)22(14)15-6-8-16(23)9-7-15/h6-12,18,26H,2-5,13H2,1H3	AFZGUFJUAJQREI-UHFFFAOYSA-N	29968	arylpyrazole, 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143413	85147731							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54581	Cc1c(CNC2CCCC2)nn(c1-c1cccnc1)-c1ccc(Cl)cc1Cl	InChI=1S/C21H22Cl2N4/c1-14-19(13-25-17-6-2-3-7-17)26-27(20-9-8-16(22)11-18(20)23)21(14)15-5-4-10-24-12-15/h4-5,8-12,17,25H,2-3,6-7,13H2,1H3	ZISZDFROUCQXSA-UHFFFAOYSA-N	29970	arylpyrazole, 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29970&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143415	85147733							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54582	Cc1c(CNC2CCCC2)nn(c1-c1cccnc1)-c1ncccc1Cl	InChI=1S/C20H22ClN5/c1-14-18(13-24-16-7-2-3-8-16)25-26(20-17(21)9-5-11-23-20)19(14)15-6-4-10-22-12-15/h4-6,9-12,16,24H,2-3,7-8,13H2,1H3	GZENXSQONSXYLR-UHFFFAOYSA-N	29972	arylpyrazole, 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143417	85147735							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54583	Cc1c(CNC2CCCC2)nn(c1-c1ccc(Cl)nc1)-c1ncccc1Cl	InChI=1S/C20H21Cl2N5/c1-13-17(12-24-15-5-2-3-6-15)26-27(20-16(21)7-4-10-23-20)19(13)14-8-9-18(22)25-11-14/h4,7-11,15,24H,2-3,5-6,12H2,1H3	DLZARUDZVNDGHQ-UHFFFAOYSA-N	29973	arylpyrazole, 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29973&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143418	85147736							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54584	Cc1c(CNC2CCCC2)nn(c1-c1ccc(C)nc1)-c1ncccc1Cl	InChI=1S/C21H24ClN5/c1-14-9-10-16(12-24-14)20-15(2)19(13-25-17-6-3-4-7-17)26-27(20)21-18(22)8-5-11-23-21/h5,8-12,17,25H,3-4,6-7,13H2,1-2H3	NZHBOZROXDLINW-UHFFFAOYSA-N	29974	arylpyrazole, 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29974	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29974&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143419	85147737							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54585	Cc1c(CNC2CCCC2)nn(c1-c1cncc(C)c1)-c1ncccc1Cl	InChI=1S/C21H24ClN5/c1-14-10-16(12-23-11-14)20-15(2)19(13-25-17-6-3-4-7-17)26-27(20)21-18(22)8-5-9-24-21/h5,8-12,17,25H,3-4,6-7,13H2,1-2H3	ATNVLHUUAGRLAR-UHFFFAOYSA-N	29977	arylpyrazole, 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29977	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29977&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143422	85147740							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54586	Cc1c(CNC2CCCC2)nn(c1-c1ccc(C)nc1)-c1ncc(Cl)cc1Cl	InChI=1S/C21H23Cl2N5/c1-13-7-8-15(10-24-13)20-14(2)19(12-25-17-5-3-4-6-17)27-28(20)21-18(23)9-16(22)11-26-21/h7-11,17,25H,3-6,12H2,1-2H3	ALMZVCUSOYGRHT-UHFFFAOYSA-N	29981	arylpyrazole, 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1200					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799051		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29981	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29981&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143426	85147744							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54592	Cc1c(CNC2CCCC2F)nn(c1-c1ccc(C)nc1)-c1ncccc1Cl	InChI=1S/C21H23ClFN5/c1-13-8-9-15(11-25-13)20-14(2)19(12-26-18-7-3-6-17(18)23)27-28(20)21-16(22)5-4-10-24-21/h4-5,8-11,17-18,26H,3,6-7,12H2,1-2H3	YPPWGAAMPXLSEU-UHFFFAOYSA-N	29982	arylpyrazole, 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799050		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29982&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143427	85147745							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54593	Cc1c(CN[C@H]2CC[C@@H](F)C2)nn(c1-c1ccc(C)nc1)-c1ncccc1Cl |r|	InChI=1S/C21H23ClFN5/c1-13-5-6-15(11-25-13)20-14(2)19(12-26-17-8-7-16(23)10-17)27-28(20)21-18(22)4-3-9-24-21/h3-6,9,11,16-17,26H,7-8,10,12H2,1-2H3	BUSSQQRPMMHCBN-UHFFFAOYSA-N	29983	arylpyrazole, 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 29000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799050		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29983	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29983&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143428	85147746							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54594	Cc1c(CNC2CCC(F)(F)C2)nn(c1-c1ccc(C)nc1)-c1ncccc1Cl	InChI=1S/C21H22ClF2N5/c1-13-5-6-15(11-26-13)19-14(2)18(12-27-16-7-8-21(23,24)10-16)28-29(19)20-17(22)4-3-9-25-20/h3-6,9,11,16,27H,7-8,10,12H2,1-2H3	DMJMZMXUINSYIJ-UHFFFAOYSA-N	29984	arylpyrazole, 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799050		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29984&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143429	85147747							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54595	Cc1c(CNC2CCCC2)nn(c1-c1cnc(C)c(F)c1)-c1ncccc1Cl	InChI=1S/C21H23ClFN5/c1-13-19(12-26-16-6-3-4-7-16)27-28(21-17(22)8-5-9-24-21)20(13)15-10-18(23)14(2)25-11-15/h5,8-11,16,26H,3-4,6-7,12H2,1-2H3	VMGWUSHQPDSHSZ-UHFFFAOYSA-N	29985	arylpyrazole, 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799050		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143430	85147748							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54596	Cc1c(CN[C@H]2CC[C@@H](F)C2)nn(c1-c1cnc(C)c(F)c1)-c1ncccc1Cl |r|	InChI=1S/C21H22ClF2N5/c1-12-19(11-27-16-6-5-15(23)9-16)28-29(21-17(22)4-3-7-25-21)20(12)14-8-18(24)13(2)26-10-14/h3-4,7-8,10,15-16,27H,5-6,9,11H2,1-2H3	CTNODSDKBPJKAA-UHFFFAOYSA-N	29986	arylpyrazole, 31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 41000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.116	10.7270/Q289145G	19447610	aid1799050		Kobayashi, K; Uchiyama, M; Ito, H; Takahashi, H; Yoshizumi, T; Sakoh, H; Nagatomi, Y; Asai, M; Miyazoe, H; Tsujita, T; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Ohta, H; Okamoto, O	7/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29986	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29986&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143431	85147749							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54605	CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@@]1(C)CC[C@@H](CC1)NC(=O)OC |r,wU:20.23,24.30,wD:20.22,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,;3.2,3.85,;3.97,5.18,;4.29,2.76,;4.84,4.2,;3.59,1.39,;4.42,.1,;5.96,.17,;6.66,1.54,;5.83,2.84,;6.79,-1.12,;8.33,-1.05,;9.04,.32,;9.17,-2.34,;10.71,-2.26,)|	InChI=1S/C23H32ClN5O3/c1-4-28-9-11-29(12-10-28)19-14-18-17(13-16(19)24)26-21(27-18)20(30)23(2)7-5-15(6-8-23)25-22(31)32-3/h13-15H,4-12H2,1-3H3,(H,25,31)(H,26,27)	JSDMNVWPECZJKQ-UHFFFAOYSA-N	29989	2-Cyclohexylcarbonylbenzimidazole, 7a	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4900					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.023	10.7270/Q24J0CFR	19394217	aid1799055		Kobayashi, K; Uchiyama, M; Takahashi, H; Kawamoto, H; Ito, S; Yoshizumi, T; Nakashima, H; Kato, T; Shimizu, A; Yamamoto, I; Asai, M; Miyazoe, H; Ohno, A; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Tanaka, T; Mochidome, T; Tadano, K; Fukuroda, T; Ohta, H; Okamoto, O	6/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29989&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143434	85147752							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54606	CCN1CCN(CC1)c1cc2[nH]c(nc2cc1C)C(=O)[C@@]1(C)CC[C@@H](CC1)NC(=O)OC |r,wU:20.23,24.30,wD:20.22,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,;3.2,3.85,;3.97,5.18,;4.29,2.76,;4.84,4.2,;3.59,1.39,;4.42,.1,;5.96,.17,;6.66,1.54,;5.83,2.84,;6.79,-1.12,;8.33,-1.05,;9.04,.32,;9.17,-2.34,;10.71,-2.26,)|	InChI=1S/C24H35N5O3/c1-5-28-10-12-29(13-11-28)20-15-19-18(14-16(20)2)26-22(27-19)21(30)24(3)8-6-17(7-9-24)25-23(31)32-4/h14-15,17H,5-13H2,1-4H3,(H,25,31)(H,26,27)	WGBOTEMLMSBMCJ-UHFFFAOYSA-N	29990	2-Cyclohexylcarbonylbenzimidazole, 7b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.023	10.7270/Q24J0CFR	19394217	aid1799055		Kobayashi, K; Uchiyama, M; Takahashi, H; Kawamoto, H; Ito, S; Yoshizumi, T; Nakashima, H; Kato, T; Shimizu, A; Yamamoto, I; Asai, M; Miyazoe, H; Ohno, A; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Tanaka, T; Mochidome, T; Tadano, K; Fukuroda, T; Ohta, H; Okamoto, O	6/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29990&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143435	85147753							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54607	CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)C1(C)CCC(=O)CC1	InChI=1S/C21H27ClN4O2/c1-3-25-8-10-26(11-9-25)18-13-17-16(12-15(18)22)23-20(24-17)19(28)21(2)6-4-14(27)5-7-21/h12-13H,3-11H2,1-2H3,(H,23,24)	SYPUQPMFIUFKOF-UHFFFAOYSA-N	29991	2-Cyclohexylcarbonylbenzimidazole, 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8500					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.023	10.7270/Q24J0CFR	19394217	aid1799055		Kobayashi, K; Uchiyama, M; Takahashi, H; Kawamoto, H; Ito, S; Yoshizumi, T; Nakashima, H; Kato, T; Shimizu, A; Yamamoto, I; Asai, M; Miyazoe, H; Ohno, A; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Tanaka, T; Mochidome, T; Tadano, K; Fukuroda, T; Ohta, H; Okamoto, O	6/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143436	85147754							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54608	CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@]1(C)CC[C@@](C)(O)CC1 |r,wU:20.23,24.28,wD:20.22,24.27,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,;3.2,3.85,;3.97,5.18,;4.29,2.76,;4.84,4.2,;5.83,2.84,;6.66,1.54,;5.96,.17,;5.96,-1.37,;7.45,-.23,;4.42,.1,;3.59,1.39,)|	InChI=1S/C22H31ClN4O2/c1-4-26-9-11-27(12-10-26)18-14-17-16(13-15(18)23)24-20(25-17)19(28)21(2)5-7-22(3,29)8-6-21/h13-14,29H,4-12H2,1-3H3,(H,24,25)	NXSFKUCSWRJBEE-UHFFFAOYSA-N	29992	2-Cyclohexylcarbonylbenzimidazole, 7c	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.023	10.7270/Q24J0CFR	19394217	aid1799055		Kobayashi, K; Uchiyama, M; Takahashi, H; Kawamoto, H; Ito, S; Yoshizumi, T; Nakashima, H; Kato, T; Shimizu, A; Yamamoto, I; Asai, M; Miyazoe, H; Ohno, A; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Tanaka, T; Mochidome, T; Tadano, K; Fukuroda, T; Ohta, H; Okamoto, O	6/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29992&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			9823363	85147755							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54609	CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@@]1(C)CC[C@@](C)(O)CC1 |r,wU:20.23,24.27,wD:20.22,24.28,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,;3.2,3.85,;3.97,5.18,;4.29,2.76,;4.84,4.2,;3.59,1.39,;4.42,.1,;5.96,.17,;5.96,-1.37,;7.45,-.23,;6.66,1.54,;5.83,2.84,)|	InChI=1S/C22H31ClN4O2/c1-4-26-9-11-27(12-10-26)18-14-17-16(13-15(18)23)24-20(25-17)19(28)21(2)5-7-22(3,29)8-6-21/h13-14,29H,4-12H2,1-3H3,(H,24,25)	NXSFKUCSWRJBEE-UHFFFAOYSA-N	29993	2-Cyclohexylcarbonylbenzimidazole, 7d	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3100					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.023	10.7270/Q24J0CFR	19394217	aid1799055		Kobayashi, K; Uchiyama, M; Takahashi, H; Kawamoto, H; Ito, S; Yoshizumi, T; Nakashima, H; Kato, T; Shimizu, A; Yamamoto, I; Asai, M; Miyazoe, H; Ohno, A; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Tanaka, T; Mochidome, T; Tadano, K; Fukuroda, T; Ohta, H; Okamoto, O	6/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29993&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			9823363	85147756							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54610	CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@]1(CC)CC[C@@](C)(O)CC1 |r,wU:20.23,25.29,wD:20.22,25.28,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,;3.2,3.85,;3.97,5.18,;4.29,2.76,;4.84,4.2,;6.37,4.44,;5.83,2.84,;6.66,1.54,;5.96,.17,;5.96,-1.37,;7.45,-.23,;4.42,.1,;3.59,1.39,)|	InChI=1S/C23H33ClN4O2/c1-4-23(8-6-22(3,30)7-9-23)20(29)21-25-17-14-16(24)19(15-18(17)26-21)28-12-10-27(5-2)11-13-28/h14-15,30H,4-13H2,1-3H3,(H,25,26)	IVXREHUZWIXJIB-UHFFFAOYSA-N	29994	2-Cyclohexylcarbonylbenzimidazole, 7e	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000					7.4000	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.023	10.7270/Q24J0CFR	19394217	aid1799055		Kobayashi, K; Uchiyama, M; Takahashi, H; Kawamoto, H; Ito, S; Yoshizumi, T; Nakashima, H; Kato, T; Shimizu, A; Yamamoto, I; Asai, M; Miyazoe, H; Ohno, A; Hirayama, M; Ozaki, S; Tani, T; Ishii, Y; Tanaka, T; Mochidome, T; Tadano, K; Fukuroda, T; Ohta, H; Okamoto, O	6/1/2009	7/4/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143437	85147757							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54635	C[C@@H]1CN(CCO)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl |r|	InChI=1S/C18H27ClN4OS/c1-12-11-22(7-8-24)5-6-23(12)16-10-15-14(9-13(16)19)20-17(21-15)25-18(2,3)4/h9-10,12,24H,5-8,11H2,1-4H3,(H,20,21)	PRUISXHHETXRED-UHFFFAOYSA-N	29995	CHEMBL494350::benzimidazole-based antagonist, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1600							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29995&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24857819	85147758		CHEMBL494350					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54636	CCN1CCN([C@H](C)C1)c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl |r|	InChI=1S/C18H27ClN4S/c1-6-22-7-8-23(12(2)11-22)16-10-15-14(9-13(16)19)20-17(21-15)24-18(3,4)5/h9-10,12H,6-8,11H2,1-5H3,(H,20,21)	NDISOCGETLUCIC-UHFFFAOYSA-N	29996	benzimidazole analogue, 5a	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 990							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29996&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143438	85147759							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54637	C[C@@H]1CN(CC(F)F)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl |r|	InChI=1S/C18H25ClF2N4S/c1-11-9-24(10-16(20)21)5-6-25(11)15-8-14-13(7-12(15)19)22-17(23-14)26-18(2,3)4/h7-8,11,16H,5-6,9-10H2,1-4H3,(H,22,23)	PWTDZYJFBSXIIK-UHFFFAOYSA-N	29997	benzimidazole analogue, 5b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29997&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143439	85147760							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54638	C[C@@H]1CN(CC#N)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl |r|	InChI=1S/C18H24ClN5S/c1-12-11-23(6-5-20)7-8-24(12)16-10-15-14(9-13(16)19)21-17(22-15)25-18(2,3)4/h9-10,12H,6-8,11H2,1-4H3,(H,21,22)	MQYKOKBVZHWQOH-UHFFFAOYSA-N	29999	benzimidazole analogue, 5d	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29999&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143441	85147762							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54639	C[C@@H]1CN(CCC#N)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl |r|	InChI=1S/C19H26ClN5S/c1-13-12-24(7-5-6-21)8-9-25(13)17-11-16-15(10-14(17)20)22-18(23-16)26-19(2,3)4/h10-11,13H,5,7-9,12H2,1-4H3,(H,22,23)	MFAYVOKLKRGCRN-UHFFFAOYSA-N	30000	benzimidazole analogue, 5e	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30000&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143442	85147763							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54640	C[C@@H]1CN(CC(C)=O)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl |r|	InChI=1S/C19H27ClN4OS/c1-12-10-23(11-13(2)25)6-7-24(12)17-9-16-15(8-14(17)20)21-18(22-16)26-19(3,4)5/h8-9,12H,6-7,10-11H2,1-5H3,(H,21,22)	MIXYMKFBPWKETL-UHFFFAOYSA-N	30001	benzimidazole analogue, 5f	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143443	85147764							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54641	CCOC(=O)N1CCC(C)(CC1)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CC)CC1	InChI=1S/C22H32ClN5O2S/c1-4-26-10-12-27(13-11-26)19-15-18-17(14-16(19)23)24-20(25-18)31-22(3)6-8-28(9-7-22)21(29)30-5-2/h14-15H,4-13H2,1-3H3,(H,24,25)	ZUPHLBSFYJTEQV-UHFFFAOYSA-N	30004	benzimidazole analogue, 7c	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3900							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30004&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143446	85147767							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54642	CCN1CCN(CC1)c1cc2[nH]c(S[C@]3(C)CC[C@@H](CC3)NC(=O)OC)nc2cc1Cl |r,wU:14.15,wD:14.14,18.22,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;5.48,2.82,;6.5,1.67,;6.01,.21,;4.51,-.1,;3.48,1.06,;7.04,-.94,;6.55,-2.4,;5.04,-2.71,;7.57,-3.56,;7.08,-5.02,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H32ClN5O2S/c1-4-27-9-11-28(12-10-27)19-14-18-17(13-16(19)23)25-20(26-18)31-22(2)7-5-15(6-8-22)24-21(29)30-3/h13-15H,4-12H2,1-3H3,(H,24,29)(H,25,26)	ZMCNDHKXQWQHCC-UHFFFAOYSA-N	30005	benzimidazole analogue, 7d	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1500							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30005	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30005&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143432	85147768							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54643	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)NC(=O)OC)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;4.29,2.76,;4.84,4.2,;3.59,1.39,;4.42,.1,;5.96,.17,;6.66,1.54,;5.83,2.84,;6.79,-1.12,;8.33,-1.05,;9.04,.32,;9.17,-2.34,;10.71,-2.26,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H32ClN5O2S/c1-4-27-9-11-28(12-10-27)19-14-18-17(13-16(19)23)25-20(26-18)31-22(2)7-5-15(6-8-22)24-21(29)30-3/h13-15H,4-12H2,1-3H3,(H,24,29)(H,25,26)	ZMCNDHKXQWQHCC-UHFFFAOYSA-N	29987	benzimidazole analogue, 7e::benzimidazole derivative, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3500							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143432	85147750							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54644	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](C3)NC(=O)OC)nc2cc1Cl |r|	InChI=1S/C21H30ClN5O2S/c1-4-26-7-9-27(10-8-26)18-12-17-16(11-15(18)22)24-19(25-17)30-21(2)6-5-14(13-21)23-20(28)29-3/h11-12,14H,4-10,13H2,1-3H3,(H,23,28)(H,24,25)	CDOAKUQOANRBJU-UHFFFAOYSA-N	30007	Racemate::benzimidazole analogue, 7f	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30007&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143447	85147770							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54645	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)NC(C)=O)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.55,-2.4,;7.57,-3.56,;5.04,-2.71,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H32ClN5OS/c1-4-27-9-11-28(12-10-27)20-14-19-18(13-17(20)23)25-21(26-19)30-22(3)7-5-16(6-8-22)24-15(2)29/h13-14,16H,4-12H2,1-3H3,(H,24,29)(H,25,26)	PIINFVJVFRCBPD-UHFFFAOYSA-N	30008	benzimidazole analogue, 7g	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30008&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143448	85147771							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54646	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)N(C)C(C)=O)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;4.29,2.76,;4.84,4.2,;3.59,1.39,;4.42,.1,;5.96,.17,;6.66,1.54,;5.83,2.84,;6.79,-1.12,;6.09,-2.49,;8.33,-1.05,;9.17,-2.34,;9.04,.32,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C23H34ClN5OS/c1-5-28-10-12-29(13-11-28)21-15-20-19(14-18(21)24)25-22(26-20)31-23(3)8-6-17(7-9-23)27(4)16(2)30/h14-15,17H,5-13H2,1-4H3,(H,25,26)	XDEIWEDXCSPRJV-UHFFFAOYSA-N	29988	benzimidazole analogue, 7h::benzimidazole derivative, 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29988	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29988&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143433	85147751							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54647	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)NS(C)(=O)=O)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.55,-2.4,;7.57,-3.56,;5.06,-2,;5.78,-3.74,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C21H32ClN5O2S2/c1-4-26-9-11-27(12-10-26)19-14-18-17(13-16(19)22)23-20(24-18)30-21(2)7-5-15(6-8-21)25-31(3,28)29/h13-15,25H,4-12H2,1-3H3,(H,23,24)	DGQCODLOOZUGMQ-UHFFFAOYSA-N	30010	benzimidazole analogue, 7i	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30010&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143449	85147773							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54648	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)N3CCCC3=O)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.75,-2.46,;8.11,-3.19,;9.22,-2.13,;8.56,-.74,;9.3,.61,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C24H34ClN5OS/c1-3-28-11-13-29(14-12-28)21-16-20-19(15-18(21)25)26-23(27-20)32-24(2)8-6-17(7-9-24)30-10-4-5-22(30)31/h15-17H,3-14H2,1-2H3,(H,26,27)	IKTSAJDKFAUOAJ-UHFFFAOYSA-N	30011	benzimidazole analogue, 7j	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30011&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143450	85147774							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54649	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)C(=O)NC)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.55,-2.4,;8.54,-.63,;9.57,-1.79,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H32ClN5OS/c1-4-27-9-11-28(12-10-27)19-14-18-17(13-16(19)23)25-21(26-18)30-22(2)7-5-15(6-8-22)20(29)24-3/h13-15H,4-12H2,1-3H3,(H,24,29)(H,25,26)	DJYBISQALHOGEU-UHFFFAOYSA-N	30012	benzimidazole analogue, 7k	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30012&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143451	85147775							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54650	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)S(C)(=O)=O)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;8.52,-.54,;5.7,-1.71,;7.81,-2.28,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C21H31ClN4O2S2/c1-4-25-9-11-26(12-10-25)19-14-18-17(13-16(19)22)23-20(24-18)29-21(2)7-5-15(6-8-21)30(3,27)28/h13-15H,4-12H2,1-3H3,(H,23,24)	RIQBOXPEDVGJOO-UHFFFAOYSA-N	30013	benzimidazole analogue, 7l	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30013&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143452	85147776							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54651	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)c3nnn(C)n3)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.68,-2.44,;7.99,-3.24,;9.16,-2.24,;10.66,-2.6,;8.57,-.82,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H31ClN8S/c1-4-30-9-11-31(12-10-30)19-14-18-17(13-16(19)23)24-21(25-18)32-22(2)7-5-15(6-8-22)20-26-28-29(3)27-20/h13-15H,4-12H2,1-3H3,(H,24,25)	RZCBOZFAZHVGKU-UHFFFAOYSA-N	30014	benzimidazole analogue, 7m	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4400							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30014&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143453	85147777							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54652	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)c3nnnn3C)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;8.57,-.82,;9.16,-2.24,;7.99,-3.24,;6.68,-2.44,;5.25,-3.03,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H31ClN8S/c1-4-30-9-11-31(12-10-30)19-14-18-17(13-16(19)23)24-21(25-18)32-22(2)7-5-15(6-8-22)20-26-27-28-29(20)3/h13-15H,4-12H2,1-3H3,(H,24,25)	DLGAGPFJWVXJOR-UHFFFAOYSA-N	30015	benzimidazole analogue, 7n	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6300							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30015&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143454	85147778							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54653	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)c3nc(C)no3)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;8.57,-.82,;9.16,-2.24,;10.66,-2.6,;7.99,-3.24,;6.68,-2.44,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C23H31ClN6OS/c1-4-29-9-11-30(12-10-29)20-14-19-18(13-17(20)24)26-22(27-19)32-23(3)7-5-16(6-8-23)21-25-15(2)28-31-21/h13-14,16H,4-12H2,1-3H3,(H,26,27)	FCVWUDUFOJNPPC-UHFFFAOYSA-N	30016	benzimidazole analogue, 7o	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 380							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30016&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143455	85147779							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54654	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)c3nnco3)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.69,-2.44,;8.01,-3.24,;9.17,-2.23,;8.57,-.81,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C22H29ClN6OS/c1-3-28-8-10-29(11-9-28)19-13-18-17(12-16(19)23)25-21(26-18)31-22(2)6-4-15(5-7-22)20-27-24-14-30-20/h12-15H,3-11H2,1-2H3,(H,25,26)	HGKNLNTUOBXSNA-UHFFFAOYSA-N	30017	benzimidazole analogue, 7p	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3400							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143456	85147780							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
54655	CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)c3nnc(C)o3)nc2cc1Cl |r,wU:14.15,18.22,wD:14.14,(-10.04,.77,;-8.71,,;-7.38,.77,;-7.38,2.31,;-6.04,3.08,;-4.71,2.31,;-4.71,.77,;-6.04,,;-3.38,3.08,;-2.04,2.31,;-.71,3.08,;.76,2.6,;1.66,3.85,;3.2,3.85,;3.97,2.52,;4.74,3.85,;3.48,1.06,;4.51,-.1,;6.01,.21,;6.5,1.67,;5.48,2.82,;7.04,-.94,;6.69,-2.44,;8.01,-3.24,;9.17,-2.23,;10.67,-2.58,;8.57,-.81,;.76,5.1,;-.71,4.62,;-2.04,5.39,;-3.38,4.62,;-4.71,5.39,)|	InChI=1S/C23H31ClN6OS/c1-4-29-9-11-30(12-10-29)20-14-19-18(13-17(20)24)25-22(26-19)32-23(3)7-5-16(6-8-23)21-28-27-15(2)31-21/h13-14,16H,4-12H2,1-3H3,(H,25,26)	HQWTVKFLZGDJRG-UHFFFAOYSA-N	30018	benzimidazole analogue, 7q	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							Curated from the literature by BindingDB	10.1016/j.bmcl.2009.04.022	10.7270/Q20R9MRX	19398200	aid1799056		Kobayashi, K; Kato, T; Yamamoto, I; Shimizu, A; Mizutani, S; Asai, M; Kawamoto, H; Ito, S; Yoshizumi, T; Hirayama, M; Ozaki, S; Ohta, H; Okamoto, O	6/1/2009	7/2/2009	Banyu Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30018&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44143457	85147781							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118687	C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2C[C@@H](Nc3ccc4c(n3)CCNC4)CN21	InChI=1S/C18H16ClN3O/c1-13-7-9-14(10-8-13)16-11-17(20-18(23)12-19)22(21-16)15-5-3-2-4-6-15/h2-11H,12H2,1H3,(H,20,23)	RFGPJLHZNCTJPI-UHFFFAOYSA-N	70584	5-[(4R,7R,8aS)-4-methyl-7-(5,6,7,8-tetrahydro-1,6-naphthyridin-2-ylamino)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]quinoline-8-carbonitrile::US12486273, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>20000							US Patent	10.1021/jm900173b	10.7270/Q2DZ0F3Q		aid1798978	US12486273	Chen, D; Dey, F; Ding, D; Xu, H; Zhu, W; Zou, G	12/2/2025	4/13/2026	Hoffmann-La Roche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=70584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=70584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			156388159	252648614							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118688	C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2C[C@@H](Nc3cc4c(cn3)CCNC4)CN21	InChI=1S/C23H26N2O5S/c1-25(18-7-4-3-5-8-18)16-6-15-24-23(26)22-14-11-20(30-22)17-31(27,28)21-12-9-19(29-2)10-13-21/h3-5,7-14H,6,15-17H2,1-2H3,(H,24,26)	FSBKXGCTDHERMM-UHFFFAOYSA-N	71749	5-[(4R,7R,8aS)-4-methyl-7-(5,6,7,8-tetrahydro-2,6-naphthyridin-3-ylamino)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]quinoline-8-carbonitrile::US12486273, Example 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>20000							US Patent	10.1021/jm900173b	10.7270/Q2DZ0F3Q		aid1798978	US12486273	Chen, D; Dey, F; Ding, D; Xu, H; Zhu, W; Zou, G	12/2/2025	4/13/2026	Hoffmann-La Roche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71749	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71749&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			156388140	252649023							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118689	C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2C[C@@H](Nc3ccc4c(n3)CNCC4)CN21	InChI=1S/C12H14N2O/c1-10(15)13-7-9-14-8-6-11-4-2-3-5-12(11)14/h2-6,8H,7,9H2,1H3,(H,13,15)	AAIUCVHMISBIEU-UHFFFAOYSA-N	71750	5-[(4R,7R,8aS)-4-methyl-7-(5,6,7,8-tetrahydro-1,7-naphthyridin-2-ylamino)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]quinoline-8-carbonitrile::US12486273, Example 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>20000							US Patent	10.1021/jm900173b	10.7270/Q2DZ0F3Q		aid1798978	US12486273	Chen, D; Dey, F; Ding, D; Xu, H; Zhu, W; Zou, G	12/2/2025	4/13/2026	Hoffmann-La Roche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			156388174	252649024							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118690	[2H]c1ccc2c(N3C[C@@H]4C[C@H](N5CCNCC5)CN4[C@H](C)C3)ccc(C#N)c2n1	InChI=1S/C11H10N2O/c1-8-2-4-9(5-3-8)10-6-7-11(14)13-12-10/h2-7H,1H3,(H,13,14)	LARMXWJBFDZFNL-UHFFFAOYSA-N	71751	5-[(4R,7S,8aS)-4-methyl-7-piperazin-1-yl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-2-deuterio-quinoline-8-carbonitrile::US12486273, Example 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>20000							US Patent	10.1021/jm900173b	10.7270/Q2DZ0F3Q		aid1798978	US12486273	Chen, D; Dey, F; Ding, D; Xu, H; Zhu, W; Zou, G	12/2/2025	4/13/2026	Hoffmann-La Roche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71751	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			164578649	252649025							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118691	[2H]c1ccc2c(N3C[C@@H]4C[C@H](N5CCC(N(C)C)CC5)CN4[C@H](C)C3)ccc(C#N)c2n1	InChI=1S/C19H21NO2/c1-4-17-19(21)20(12-15-7-5-6-13(2)10-15)16-11-14(3)8-9-18(16)22-17/h5-11,17H,4,12H2,1-3H3	NKWAPYGPOASLEV-UHFFFAOYSA-N	71752	5-[(4R,7S,8aS)-7-[4-(dimethylamino)-1-piperidyl]-4-methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-2-deuterio-quinoline-8-carbonitrile::US12486273, Example 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>20000							US Patent	10.1021/jm900173b	10.7270/Q2DZ0F3Q		aid1798978	US12486273	Chen, D; Dey, F; Ding, D; Xu, H; Zhu, W; Zou, G	12/2/2025	4/13/2026	Hoffmann-La Roche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71752	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			164578645	252649026							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118810	CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1	InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	UZWDCWONPYILKI-UHFFFAOYSA-N	50110183	Abemaciclib::LY-2835219::US10696678, Example LY2835219::US10662186, Compound LY2835219::US10988476, Compound LY2835219::US11053238, LY2835219::US11091476, Example LY2835219::US11351170, Example Abemaciclib::US10626107, Example LY2835219::US20240358711, Compound Abemaciclib::US12486280, Compound Abemaciclib	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 2690								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110183	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110183&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46220502	319493137							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118812	CC1=C(C(=O)N(c2c1cnc(n2)Nc3ccc(cn3)N4CCNCC4)C5CCCC5)C(=O)C	InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)	AHJRHEGDXFFMBM-UHFFFAOYSA-N	6309	8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido-[2,3-d]-pyrimidin-7-one 43::6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one Hydrochloride::PD 0332991::US9464092, PD0332991::Palbociclib::Ibrance::US10189849, PD0332991::US9957276, PD0332991::US10464927, Compound Palbociclib::US10696682, Compound PD0332991::US10927120, PD0332991::US10626107, Example Palbociclib::US20250066372, Example Palbociclib::US12312355, Compound Palbociclib::US12486280, Compound Palbociclib	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1440								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6309	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6309&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	LQQ	2EUF,5L2I,7N7O,9PDE,9PDF,9PDG	5330286	8035907			DB09073				1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118815	C=CCC1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C24H37N3O5S/c1-6-12-27(13-7-2)14-8-11-25-23(28)17-33(29)16-20-18(3)32-24(26-20)19-9-10-21(30-4)22(15-19)31-5/h9-10,15H,6-8,11-14,16-17H2,1-5H3,(H,25,28)	XVLQKWUHSJTRNZ-UHFFFAOYSA-N	71772	US12486280, Compound A45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1430								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327347	252649046							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118817	CCCC1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C15H15N3O2S/c1-20-12-6-4-7-13(9-12)21-14-8-3-2-5-11(14)10-17-18-15(16)19/h2-10H,1H3,(H3,16,18,19)	OCTNWVNIGTXPOM-UHFFFAOYSA-N	71997	US12486280, Compound A46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1950								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71997&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327348	252649264							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118819	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCOC6(CCOC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C16H12N4S3/c1-2-5-11(6-3-1)15-17-12(9-22-15)10-23-16-18-14(19-20-16)13-7-4-8-21-13/h1-9H,10H2,(H,18,19,20)	XGYBZAGCTWLSSZ-UHFFFAOYSA-N	71998	US12486280, Compound A40	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7990								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71998&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327237	252649265							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118821	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCOC(C)(C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C19H20N2O4S/c1-12(2)10-21-17(22)14-6-4-5-7-15(14)20-19(21)26-11-13-8-9-16(25-13)18(23)24-3/h4-9,12H,10-11H2,1-3H3	SENSWESYERGKEI-UHFFFAOYSA-N	71999	US12486280, Compound A48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1080								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71999&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327356	252649266							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118823	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCOC(C)(CCN(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C27H21NO4/c1-18-16-20(12-13-23(29)19-8-4-3-5-9-19)25-21(17-18)14-15-27(32-25)28(2)26(30)22-10-6-7-11-24(22)31-27/h3-17H,1-2H3	WPSRXZHMOUHWJO-UHFFFAOYSA-N	72000	US12486280, Compound A4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5090								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72000&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327203	252649267							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118825	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCNC(C)(C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C20H21N3O3/c1-13-9-14(2)11-16(10-13)21-17(24)12-23-18(25)20(3,22-19(23)26)15-7-5-4-6-8-15/h4-11H,12H2,1-3H3,(H,21,24)(H,22,26)	NCXNKMQSOIDKRZ-UHFFFAOYSA-N	72001	US12486280, Compound A44	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3040								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327239	252649268							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118828	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(CCN(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C22H18F2N4/c23-17-8-4-14(5-9-17)12-16-2-1-3-19-20(16)27-22-25-13-26-28(22)21(19)15-6-10-18(24)11-7-15/h4-13,19,21H,1-3H2	DDCFKBZUDIRCPH-UHFFFAOYSA-N	72002	US12486280, Compound A1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 2900								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72002&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327202	252649269							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118831	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C17H24N4O2S/c1-4-21(9-14(22)18-10(2)3)8-13-19-16(23)15-11-6-5-7-12(11)24-17(15)20-13/h10H,4-9H2,1-3H3,(H,18,22)(H,19,20,23)	OWOQPMSOBMLOQB-UHFFFAOYSA-N	72003	US12486280, Compound A2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3380								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327206	252649270							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118834	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCOC(C)(CC(C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C21H18N2O3/c1-14-8-10-15(11-9-14)21-20(16-5-2-3-6-18(16)22-21)17(13-23(24)25)19-7-4-12-26-19/h2-12,17,22H,13H2,1H3	PFYOYTNZIIHWRS-UHFFFAOYSA-N	72004	US12486280, Compound A25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3470								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72004&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327214	252649271							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118836	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCOC(C)(CC(C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C20H20N4O2S2/c1-4-9-24-19(26)13-7-5-6-8-14(13)21-20(24)27-10-15-22-17(25)16-11(2)12(3)28-18(16)23-15/h5-8H,4,9-10H2,1-3H3,(H,22,23,25)	JTIXAEZLCCVFDJ-UHFFFAOYSA-N	72005	US12486280, Compound A24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 160								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72005	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72005&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327214	252649272							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118838	CNCC[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1			72006	US12486280, Compound A5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 6260								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72006&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327207	252649273							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118841	CNCC[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C15H14N2O4S/c1-19-12-6-10-11(7-13(12)20-2)16-15(22)17(14(10)18)8-9-4-3-5-21-9/h3-7H,8H2,1-2H3,(H,16,22)	MJHAOKKNQKOMKD-UHFFFAOYSA-N	72007	US12486280, Compound A22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3550								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72007&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327207	252649274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118844	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCO)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C9H7Cl2N7O2/c10-6-2-7(11)8(18(19)20)1-5(6)3-13-15-9-16-14-4-17(9)12/h1-4,15H,12H2	AXUOJPVZTQZVHA-UHFFFAOYSA-N	72008	US12486280, Compound A49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7460								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72008&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327352	252649275							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118846	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(CCO)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C20H20N2O3S/c1-14-4-6-15(7-5-14)21-19(23)13-22-16(9-11-20(24)25)8-10-17(22)18-3-2-12-26-18/h2-8,10,12H,9,11,13H2,1H3,(H,21,23)(H,24,25)	BODNSNQRNAWXOQ-UHFFFAOYSA-N	72009	US12486280, Compound A50	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5320								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72009&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327265	252649276							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118849	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCN(C)C(C)(C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C22H21ClFN3O4S/c23-18-8-7-16(14-21(18)32(29,30)25-15-17-4-3-13-31-17)22(28)27-11-9-26(10-12-27)20-6-2-1-5-19(20)24/h1-8,13-14,25H,9-12,15H2	ONLRVHVVOCMKSW-UHFFFAOYSA-N	72010	US12486280, Compound A43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4130								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72010&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327228	252649277							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118852	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@]6(CCN(C(=O)OC(C)(C)C)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C16H13Cl3N2O4/c1-9(25-12-4-2-10(17)3-5-12)16(23)24-8-14(22)21-15-13(19)6-11(18)7-20-15/h2-7,9H,8H2,1H3,(H,20,21,22)	RINYLAXESJNLFN-UHFFFAOYSA-N	72011	US12486280, Compound A41	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 73920								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72011&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327226	252649278							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118854	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@]6(CCN(C(=O)OC(C)(C)C)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C18H23N5O6S/c1-4-22(5-2)30(27,28)17-12-13(23(25)26)10-11-15(17)20-21-18(24)19-14-8-6-7-9-16(14)29-3/h6-12,20H,4-5H2,1-3H3,(H2,19,21,24)	ARMPGCJEAQVRJU-UHFFFAOYSA-N	72012	US12486280, Compound A42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 34870								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72012&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327227	252649279							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118856	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@]6(CCN(C)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C26H30N2O4/c1-3-31-24-18-23(28-12-14-30-15-13-28)25(32-4-2)17-22(24)27-26(29)16-20-10-7-9-19-8-5-6-11-21(19)20/h5-11,17-18H,3-4,12-16H2,1-2H3,(H,27,29)	MAUGWXQTENMHOE-UHFFFAOYSA-N	72013	US12486280, Compound A39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 6620								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72013&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327225	252649280							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118859	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@]6(CCN(C)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C31H32N4O2/c36-30(25-15-16-26-27(22-25)32-28-14-8-3-9-17-35(28)31(26)37)34-20-18-33(19-21-34)29(23-10-4-1-5-11-23)24-12-6-2-7-13-24/h1-2,4-7,10-13,15-16,22,29H,3,8-9,14,17-21H2	BXSFOIVYQMOQAG-UHFFFAOYSA-N	72014	US12486280, Compound A38	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7230								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72014&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327250	252649281							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118862	CC(=O)N1CC[C@]2(CN(Cc3ccc(Nc4ncc(F)c(-c5cc(F)c6nc(C)n(C(C)C)c6c5)n4)nc3)CCO2)C1	InChI=1S/C21H20ClN3O3S2/c1-12-7-8-29-18(12)10-15-20(27)25(16-9-13(22)3-6-17(16)28-2)21(24-15)30-11-19(26)23-14-4-5-14/h3,6-10,14H,4-5,11H2,1-2H3,(H,23,26)	JEKBQPQHBREVFS-UHFFFAOYSA-N	72015	US12486280, Compound A37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 6860								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72015&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327231	252649282							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118865	CC(=O)N1CC[C@@]2(CN(Cc3ccc(Nc4ncc(F)c(-c5cc(F)c6nc(C)n(C(C)C)c6c5)n4)nc3)CCO2)C1	InChI=1S/C23H19NO5S/c1-28-14-9-11-15(12-10-14)30(26,27)24-19-13-18-22-20(25)7-4-8-21(22)29-23(18)17-6-3-2-5-16(17)19/h2-3,5-6,9-13,24H,4,7-8H2,1H3	JWTUGKPRERNBNS-UHFFFAOYSA-N	72016	US12486280, Compound A36	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 10810								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72016&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327249	252649283							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118868	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@]6(CCN(S(C)(=O)=O)C6)C5)cn4)ncc3F)cc2n1C(C)C			72017	US12486280, Compound A31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 10230								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327220	252649284							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118871	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@]6(CCN(S(C)(=O)=O)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C21H15F3N4OS/c1-13-12-30-20(26-13)17-11-25-28(16-8-3-2-4-9-16)18(17)27-19(29)14-6-5-7-15(10-14)21(22,23)24/h2-12H,1H3,(H,27,29)	AGAHBUGKJJYNCW-UHFFFAOYSA-N	72018	US12486280, Compound A32	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 17410								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72018&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327219	252649285							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118874	COC(=O)N1CC[C@]2(CN(Cc3ccc(Nc4ncc(F)c(-c5cc(F)c6nc(C)n(C(C)C)c6c5)n4)nc3)CCO2)C1	InChI=1S/C16H23NO5/c1-5-7-8-13(19)22-9-12(18)15-10(3)14(11(4)17-15)16(20)21-6-2/h17H,5-9H2,1-4H3	ZOJVDZJROMYUHY-UHFFFAOYSA-N	72019	US12486280, Compound A30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 16540								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327218	252649286							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118877	COC(=O)N1CC[C@@]2(CN(Cc3ccc(Nc4ncc(F)c(-c5cc(F)c6nc(C)n(C(C)C)c6c5)n4)nc3)CCO2)C1	InChI=1S/C11H10N4O4S/c16-10(17)6-20-11-12-13-14-15(11)7-1-2-8-9(5-7)19-4-3-18-8/h1-2,5H,3-4,6H2,(H,16,17)	TUYFGEYPHSAPTE-UHFFFAOYSA-N	72020	US12486280, Compound A33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20060								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72020&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327229	252649287							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118880	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@]6(CCNC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C22H28N2O4S/c1-15-11-16(2)14-24(13-15)22(25)18-10-9-17(3)21(12-18)29(26,27)23-19-7-5-6-8-20(19)28-4/h5-10,12,15-16,23H,11,13-14H2,1-4H3	VFUQTHVFXSUIAI-UHFFFAOYSA-N	72021	US12486280, Compound A34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7210								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327224	252649288							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118882	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@]6(CCNC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C17H11ClF3N3O3S2/c1-27-12-4-8(2-3-11(12)25)5-13-15(26)24(16(28)29-13)23-14-10(18)6-9(7-22-14)17(19,20)21/h2-7,25H,1H3,(H,22,23)	DYMWDFDNPDHJPE-UHFFFAOYSA-N	72022	US12486280, Compound A35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7160								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72022&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327230	252649289							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118884	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(C[C@@H](C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C21H23N5O3S/c27-20(6-3-15-30-21-22-18-4-1-2-5-19(18)23-21)25-13-11-24(12-14-25)16-7-9-17(10-8-16)26(28)29/h1-2,4-5,7-10H,3,6,11-15H2,(H,22,23)	IMTLAJUSIIVOOU-UHFFFAOYSA-N	72023	US12486280, Compound A26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 8630								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72023&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327217	252649290							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118887	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(C[C@H](C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C16H16N4O2S/c1-8-3-11-10(5-15(21)22-12(11)4-9(8)2)7-23-16-19-13(17)6-14(18)20-16/h3-6H,7H2,1-2H3,(H4,17,18,19,20)	POHMZEAFLNNLTE-UHFFFAOYSA-N	72024	US12486280, Compound A27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 6570								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72024&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327221	252649291							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118890	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCOC(C)(CO)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C17H14ClN3O2S/c18-12-6-7-15(23-13-4-2-1-3-5-13)14(10-12)20-16(22)11-21-8-9-24-17(21)19/h1-10,19H,11H2,(H,20,22)	GKMONRSASOZVEV-UHFFFAOYSA-N	72025	US12486280, Compound A51	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 38400								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72025&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327353	252649292							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118892	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(C[C@H](C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C21H16N4O/c26-18-14-8-7-13-17(18)24-25-21-22-19(15-9-3-1-4-10-15)20(23-21)16-11-5-2-6-12-16/h1-14,26H,(H,22,23)	ATEQMZYYZRYXHI-UHFFFAOYSA-N	72026	US12486280, Compound A23	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 6470								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72026&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327212	252649293							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118895	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(C[C@@H](C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C25H20N2O3/c1-30-20-14-12-19(13-15-20)24(29)17-27-22-10-6-5-9-21(22)26-25(27)23(28)16-11-18-7-3-2-4-8-18/h2-16H,17H2,1H3	AVRWJSHUUIQGJM-UHFFFAOYSA-N	72027	US12486280, Compound A28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 2600								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327222	252649294							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118898	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(C[C@@H](C)O)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C27H25N3O5S/c1-3-34-25(31)18-35-22-12-11-19(14-23(22)33-2)15-24-26(32)30(17-20-8-7-13-28-16-20)27(36-24)29-21-9-5-4-6-10-21/h4-16H,3,17-18H2,1-2H3	YNDQZUWYUWFKLA-UHFFFAOYSA-N	72028	US12486280, Compound A52	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 15400								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72028&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327351	252649295							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118900	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(C[C@H](C)O)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C19H13N2O6/c1-25-11-6-4-5-10(9-11)14-15-17(27-18(20)16(14)21(23)24)12-7-2-3-8-13(12)26-19(15)22/h2-9,14,20H,1H3/q-1/p+1	BJQKDLJPCFVRGV-UHFFFAOYSA-O	72029	US12486280, Compound A53	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 11900								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72029	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72029&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327355	252649296							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118902	CCC[C@@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCN1	InChI=1S/C21H17ClN6S/c1-14-13-15(2)24-20(23-14)29-21-26-18(22)25-19(27-21)28(16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13H,1-2H3	PKMXDZDFZMYHGS-UHFFFAOYSA-N	72030	US12486280, Compound A47	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5170								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72030&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327349	252649297							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118905	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CCOCC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C23H24BrNO5/c1-6-30-23(28)17-14(4)25(15-9-7-12(2)8-10-15)20-16(11-13(3)26)19(24)22(29-5)21(27)18(17)20/h7-10,27H,6,11H2,1-5H3	AJMKMNNPRYQYGQ-UHFFFAOYSA-N	72031	US12486280, Compound A19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7070								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327209	252649298							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118908	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCNC(C)(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C18H17F4N3O3/c1-11-5-3-4-6-14(11)24-25-17(16(27)28-2,18(20,21)22)23-15(26)12-7-9-13(19)10-8-12/h3-10,24-25H,1-2H3,(H,23,26)	XNAKXECUCKEXNC-UHFFFAOYSA-N	72032	US12486280, Compound A7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4240								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72032&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327359	252649299							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118910	CC(=O)N(C)CC[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C22H23ClN2O3/c1-27-21-11-16(12-24-14-19(26)18-5-3-2-4-6-18)7-9-20(21)28-15-17-8-10-22(23)25-13-17/h2-11,13,19,24,26H,12,14-15H2,1H3	AHXZIWLPQAPOAT-UHFFFAOYSA-N	72033	US12486280, Compound A8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 11300								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72033&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327208	252649300							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118913	CCOCC[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C24H26N2O3/c1-16(18-13-12-17-7-2-3-8-19(17)15-18)25-22(27)11-6-14-26-23(28)20-9-4-5-10-21(20)24(26)29/h4-5,9-10,12-13,15-16H,2-3,6-8,11,14H2,1H3,(H,25,27)	AWIMMPMZTLQNIH-UHFFFAOYSA-N	72034	US12486280, Compound A54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 108000								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72034&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327254	252649301							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118915	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CC(F)(F)C6)C5)cn4)ncc3F)cc2n1C(C)C			72035	US12486280, Compound A12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12800								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72035&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327467	242053542							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118918	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCNCC(F)(F)F)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C20H20N2O3S/c1-14-5-9-16(10-6-14)21-22-19(23)20(24,18-4-3-13-26-18)15-7-11-17(25-2)12-8-15/h3-13,21,24H,1-2H3,(H,22,23)	VFOQDVWSFFOOPM-UHFFFAOYSA-N	72036	US12486280, Compound A9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 14500								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327466	252649302							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118921	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CC(C)(O)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C14H17N3OS2/c1-2-3-8-15-14(19)17-16-13(18)11-9-20-12-7-5-4-6-10(11)12/h4-7,9H,2-3,8H2,1H3,(H,16,18)(H2,15,17,19)	XCCJUOKMJHPDBO-UHFFFAOYSA-N	72037	US12486280, Compound A10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5520								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72037&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327253	252649303							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118923	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C23H19F4N3O2/c1-12-7-8-14(9-13(12)2)18-10-16(15-5-3-4-6-17(15)28-18)21(31)30-23(32,22(26)27)11-19(29-30)20(24)25/h3-10,20,22,32H,11H2,1-2H3	SNYVAIVACJFSEV-UHFFFAOYSA-N	72039	US12486280, Compound A21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4900								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327216	252649305							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118925	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CC(F)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C15H21NO2/c1-11-8-12(2)10-16(9-11)15(17)7-6-14-5-4-13(3)18-14/h4-7,11-12H,8-10H2,1-3H3	QXBTWHIKAPGJQH-UHFFFAOYSA-N	72040	US12486280, Compound A13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4790								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72040	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72040&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327263	252649306							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118928	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CC[C@@H](F)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C16H12ClN3OS/c17-15-14(22-13-8-6-11(18)7-9-13)10-19-20(16(15)21)12-4-2-1-3-5-12/h1-10H,18H2	IXXPFHOXPJQNGG-UHFFFAOYSA-N	72041	US12486280, Compound A15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4040								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72041&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327261	252649307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118931	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CC[C@H](F)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C18H21FN6O2S2/c1-27-8-2-7-25-16(23-24-18(25)29-11-15(20)26)9-14-10-28-17(22-14)21-13-5-3-12(19)4-6-13/h3-6,10H,2,7-9,11H2,1H3,(H2,20,26)(H,21,22)	OFCDIZYCKYKPJA-UHFFFAOYSA-N	72042	US12486280, Compound A14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4990								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72042&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327255	252649308							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118934	Cc1cnc(Nc2ccc(CN3CCO[C@](C)(CCNCC(F)F)C3)cn2)nc1-c1cc(F)c2nc(C)n(C(C)C)c2c1	InChI=1S/C20H16O6/c1-11-9-18(24)26-20-13(11)5-8-16(23)19(20)15(22)7-4-12-3-6-14(21)17(10-12)25-2/h3-10,21,23H,1-2H3	AHCFQUJHOPVTAL-UHFFFAOYSA-N	72043	US12486280, Compound A6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5350								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72043&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327477	252649309							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118937	Cc1cnc(Nc2ccc(CN3CCO[C@](C)(CCN(C)CC(F)F)C3)cn2)nc1-c1cc(F)c2nc(C)n(C(C)C)c2c1	InChI=1S/C30H30BrN3O3/c1-18-25(29(36)37-4)26(27-23(32-18)14-30(2,3)15-24(27)35)22-17-34(16-19-10-12-21(31)13-11-19)33-28(22)20-8-6-5-7-9-20/h5-13,17,26-27H,14-16H2,1-4H3	SKQMCCDJZOEPAT-UHFFFAOYSA-N	72044	US12486280, Compound A29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 10500								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72044	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72044&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327360	252649310							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118940	CC[C@@]1(CCN(C)C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C10H12BrNO6/c11-7-1-6(2-18-9(7)17)8(16)12-10(3-13,4-14)5-15/h1-2,13-15H,3-5H2,(H,12,16)	MMDWOLAPTCFKCS-UHFFFAOYSA-N	72045	US12486280, Compound A20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3690								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72045&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327213	252649311							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118943	CCN(CC)CC[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C17H13ClFN5O3S/c18-11-3-1-10(2-4-11)14-9-15(25)20-17-21-16(22-24(14)17)23-28(26,27)13-7-5-12(19)6-8-13/h1-8,14H,9H2,(H2,20,21,22,23,25)	SIORLYYNLXLQTL-UHFFFAOYSA-N	72046	US12486280, Compound A3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7390								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72046&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327205	252649312							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118946	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CCCC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C25H24N6O2S/c1-3-30-21-10-5-4-9-19(21)20-14-17(11-12-22(20)30)27-23(32)15-34-25-29-28-24(31(25)26)16-7-6-8-18(13-16)33-2/h4-14H,3,15,26H2,1-2H3,(H,27,32)	STSMRPZDWOQDFW-UHFFFAOYSA-N	72047	US12486280, Compound A16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5810								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327262	252649313							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118949	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CC6C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C26H30N4O3/c1-29(2)21-12-8-19(9-13-21)17-28-26(33)20-10-6-18(7-11-20)16-27-22-23(25(32)24(22)31)30-14-4-3-5-15-30/h6-13,27H,3-5,14-17H2,1-2H3,(H,28,33)	IKBGLPRWBFDKIP-UHFFFAOYSA-N	72048	US12486280, Compound A11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5900								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72048&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327257	252649314							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118952	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN6CCC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C17H20BrN3O3S/c18-11-5-6-14-13(9-11)16(23)21(17(25)20-14)7-1-4-15(22)19-10-12-3-2-8-24-12/h5-6,9,12H,1-4,7-8,10H2,(H,19,22)(H,20,25)	MHYGBNCEUJHCLE-UHFFFAOYSA-N	72049	US12486280, Compound A17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5250								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72049&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327215	252649315							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118955	COC1(C)CN(CC[C@]2(C)CN(Cc3ccc(Nc4ncc(F)c(-c5cc(F)c6nc(C)n(C(C)C)c6c5)n4)nc3)CCO2)C1	InChI=1S/C19H22N2O4/c1-12-7-9-13(10-8-12)17(22)20-21-11-16(19(24)25-2)14-5-3-4-6-15(14)18(21)23/h3-6,11-13H,7-10H2,1-2H3,(H,20,22)	MBXIYCOBUAJYKB-UHFFFAOYSA-N	72050	US12486280, Compound A18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7620								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72050&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327210	252649316							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118958	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CC(=O)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C13H12N4O2S2/c1-19-11-5-8(3-4-10(11)18)7-15-16-12-9(6-14)13(20-2)17-21-12/h3-5,18H,7H2,1-2H3	GKLKMZWTLNXCKR-UHFFFAOYSA-N	72051	US12486280, Compound A55	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 11900								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72051&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327243	252649317							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118961	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CC(=O)N6CC(F)(F)C6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C21H18F3NO/c22-18-7-1-15(2-8-18)13-25-14-21(26,16-3-9-19(23)10-4-16)17-5-11-20(24)12-6-17/h1-12,25-26H,13-14H2	QXCVDEJEBVQMAX-UHFFFAOYSA-N	72052	US12486280, Compound A56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 14800								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327240	252649318							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118963	CCN(CC)C(=O)C[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C17H11Cl3F3N3O2/c18-10-1-2-12(13(19)6-10)16(27)28-11(3-4-24)8-26-15-14(20)5-9(7-25-15)17(21,22)23/h1-2,5-7,11H,3,8H2,(H,25,26)	ZNQYSHGGZWLSBE-UHFFFAOYSA-N	72053	US12486280, Compound A57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 24000								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72053&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327244	252649319							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118965	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CC(=O)N6CCC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C20H18N2O3/c1-3-24-20(23)17-13-21-18(15-7-5-4-6-8-15)22-19(17)25-16-11-9-14(2)10-12-16/h4-13H,3H2,1-2H3	UFTRQACCJZGXHI-UHFFFAOYSA-N	72054	US12486280, Compound A58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 19800								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72054	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72054&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327245	252649320							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118967	CNC(=O)C[C@]1(C)CN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CCO1	InChI=1S/C18H12N2S/c19-12-15-11-16(14-7-3-1-4-8-14)13-20-18(15)21-17-9-5-2-6-10-17/h1-11,13H	WUJVDBYAKSCQDJ-UHFFFAOYSA-N	72056	US12486280, Compound A59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 10100								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72056&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327241	252649322							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118970	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CC(=O)N6CCCC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C20H17Cl2NO3S/c1-13-10-14(2)23(12-15-8-9-16(21)11-18(15)22)20(24)19(13)27(25,26)17-6-4-3-5-7-17/h3-11H,12H2,1-2H3	HDZUSZZQDJTLGH-UHFFFAOYSA-N	72057	US12486280, Compound A60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 14500								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72057	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72057&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327242	252649323							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118973	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCC56COC6)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C19H15Cl2N3OS/c20-15-7-6-14(16(21)10-15)12-25-22-11-17-18(13-4-2-1-3-5-13)23-19-24(17)8-9-26-19/h1-7,10-11H,8-9,12H2	SFSRKURQYUVABX-UHFFFAOYSA-N	72058	US12486280, Compound A61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 9530								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72058	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72058&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327470	252649324							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118975	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CC6(C5)CS(=O)(=O)C6)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C11H10N4OS/c1-8-3-2-4-9(5-8)6-12-14-11(16)10-7-17-15-13-10/h2-7H,1H3,(H,14,16)	CUXOHEUWKLHJRR-UHFFFAOYSA-N	72059	US12486280, Compound A62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3800								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72059	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72059&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			156700823	252649325							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118978	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CC6(CCC6)C5)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C18H17NO2/c1-3-21-18(20)17-15(14-9-7-13(2)8-10-14)12-19-11-5-4-6-16(17)19/h4-12H,3H2,1-2H3	JWLUGUDRRNOLMC-UHFFFAOYSA-N	72060	US12486280, Compound A63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3140								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72060	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72060&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327364	252649326							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
118980	Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CC6(C5)CC(F)(F)C6)cn4)ncc3F)cc2n1C(C)C	InChI=1S/C17H15ClN2O/c1-11-7-9-12(10-8-11)19-17(21)15-13-5-3-4-6-14(13)20(2)16(15)18/h3-10H,1-2H3,(H,19,21)	KYHTWKCDLVOIBX-UHFFFAOYSA-N	72061	US12486280, Compound A64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 4530								US Patent		10.7270/Q25H7N2R			US12486280	O''Boyle, BM; Hilf, JA; Virgil, SC; Sun, AW; Stoltz, BM; Conklin, D; McDermott, MS; O''Brien, NA; Palazzolo, MJ; Slamon, D; Bartberger, MD	12/2/2025	4/14/2026	California Institute Of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72061&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146327474	252649327							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
122422	OC(=O)c1cc(Cl)ccc1Nc1nc2cc(Cl)ccc2o1	InChI=1S/C14H8Cl2N2O3/c15-7-1-3-10(9(5-7)13(19)20)17-14-18-11-6-8(16)2-4-12(11)21-14/h1-6H,(H,17,18)(H,19,20)	JIXSZKSAROXMKT-UHFFFAOYSA-N	65906	VU0404032-1::5-chloranyl-2-[(5-chloranyl-1,3-benzoxazol-2-yl)amino]benzoic acid::cid_44216771::5-chloro-2-[(5-chloro-1,3-benzoxazol-2-yl)amino]benzoic acid	Potassium voltage-gated channel subfamily H member 2	Homo sapiens				 107200					PubChem		10.7270/Q2V69H1H		aid2638		PubChem, PC	3/22/2010	7/11/2011	Johns Hopkins Ion Channel Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44216771	252644241							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184027	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 |c:8,15|	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 6013								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184028	c1ccc2c(c1)NC(=O)N2C3CCN(CC3)CCCC(c4ccc(cc4)F)c5ccc(cc5)F	InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)	YVUQSNJEYSNKRX-UHFFFAOYSA-N	50334150	1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::Orap::CHEMBL1423::Pimozide::R-6238::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::NCGC00015802	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 18								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	1II	8ZYQ,7WLL,8GU1	16362	125084252		CHEMBL1423	DB01100		C07566		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184029	OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 |t:13|	InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2	URKOMYMAXPYINW-UHFFFAOYSA-N	50095890	2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::CHEMBL716::QUETIAPINE	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5765								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			5002	103993497		CHEMBL716	DB01224		C07397		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184030	CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)c4c5ccc(cc5on4)F	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::US8802672, Risperidone::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::RISPERDAL::R 64 766::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::CHEMBL85::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::WO2023288027, Cmpd Risperidone	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 167								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252		CHEMBL85	DB00734				1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184031	Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12	InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	GZKLJWGUPQBVJQ-UHFFFAOYSA-N	50001786	1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole::1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 3								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			60149	103916159		CHEMBL12713	DB06144		C07567		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184032	CN1CCCC[C@H]1CCN2c3ccccc3Sc4c2cc(cc4)SC	InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	KLBQZWRITKRQQV-UHFFFAOYSA-N	50002338	10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::MELLARIL::(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::CHEMBL479::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::MELLARIL-S::TP-21::THIORIDAZINE::US9504692, Thioridazine	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 191								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	LZU	4I1R,4UHX	5452	103916644		CHEMBL479	DB00679				1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
184033	c1ccc2c(c1)c(ns2)N3CCN(CC3)CCc4cc5c(cc4Cl)NC(=O)C5	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	MVWVFYHBGMAFLY-UHFFFAOYSA-N	50048803	5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::GEODON::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::ZIPRASIDONE HYDROCHLORIDE::5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::CHEMBL708::ZIPRASIDONE	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 169								PDSP Ki	10.1016/s0014-2999(02)02074-5	10.7270/Q2S75DX4	12176106			Kongsamut, S; Kang, J; Chen, XL; Roehr, J; Rampe, D	12/16/2002	5/9/2012	Aventis Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	XEF	8WTY	60854	103979184		CHEMBL708	DB00246		C07568		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
189361	NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1	InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)	ROFVXGGUISEHAM-UHFFFAOYSA-N	26739	URB 597::URB597::CHEMBL184238::3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate::URB-597::US9187413, 1a (URB597)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>10000								PDSP Ki	10.1073/pnas.0509591102	10.7270/Q2F47MQJ	16352709			Gobbi, G; Bambico, FR; Mangieri, R; Bortolato, M; Campolongo, P; Solinas, M; Cassano, T; Morgese, MG; Debonnel, G; Duranti, A; Tontini, A; Tarzia, G; Mor, M; Trezza, V; Goldberg, SR; Cuomo, V; Piomelli, D	12/20/2005	6/10/2012	Mcgill University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			1383884	57298451		CHEMBL184238					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287773	Clc1ccc(Cn2c(\C=C\C3CCN(CC4CCCCC4)C3)nc3cc(Br)ccc23)cc1	InChI=1S/C27H31BrClN3/c28-23-9-12-26-25(16-23)30-27(32(26)19-21-6-10-24(29)11-7-21)13-8-22-14-15-31(18-22)17-20-4-2-1-3-5-20/h6-13,16,20,22H,1-5,14-15,17-19H2	XDLPKLHZFXXHFQ-UHFFFAOYSA-N	149377	US8975247, EBP933	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1100							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149377&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46936062	252149332							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287774	CN1CCCC1\C=C\c1nc2cc(C)c(C)cc2n1Cc1ccc(Cl)cc1	InChI=1S/C23H26ClN3/c1-16-13-21-22(14-17(16)2)27(15-18-6-8-19(24)9-7-18)23(25-21)11-10-20-5-4-12-26(20)3/h6-11,13-14,20H,4-5,12,15H2,1-3H3	RWFDOORODPSNSN-UHFFFAOYSA-N	149378	US8975247, EBP470	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 980							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149378&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46936108	252149333							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287775	Cc1cc2nc(\C=C\C3CCNC3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H24ClN3/c1-15-11-20-21(12-16(15)2)26(14-18-3-6-19(23)7-4-18)22(25-20)8-5-17-9-10-24-13-17/h3-8,11-12,17,24H,9-10,13-14H2,1-2H3	OUVCUNKYIOXFPQ-UHFFFAOYSA-N	149379	US8975247, EBP372	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1600							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149379&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46936065	252149334							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287776	Cc1cc2nc(CC3CCNCC3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H26ClN3/c1-15-11-20-21(12-16(15)2)26(14-18-3-5-19(23)6-4-18)22(25-20)13-17-7-9-24-10-8-17/h3-6,11-12,17,24H,7-10,13-14H2,1-2H3	IELYGTRDWPOQLE-UHFFFAOYSA-N	149380	US8975247, EBP467	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1100							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149380&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46936064	252149335							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287777	Cc1cc2nc(CC3CC4CCC(C3)N4)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C24H28ClN3/c1-15-9-22-23(10-16(15)2)28(14-17-3-5-19(25)6-4-17)24(27-22)13-18-11-20-7-8-21(12-18)26-20/h3-6,9-10,18,20-21,26H,7-8,11-14H2,1-2H3	RDLMLSUNDFYREW-UHFFFAOYSA-N	149381	US8975247, EBP882	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4300							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149381	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149381&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852764	252149336							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287778	CC1CC(Cc2nc3cc(C)c(C)cc3n2Cc2ccc(Cl)cc2)CCN1	InChI=1S/C23H28ClN3/c1-15-10-21-22(11-16(15)2)27(14-18-4-6-20(24)7-5-18)23(26-21)13-19-8-9-25-17(3)12-19/h4-7,10-11,17,19,25H,8-9,12-14H2,1-3H3	DVRFMLZOJWITOD-UHFFFAOYSA-N	149382	US8975247, EBP881	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 580							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149382	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149382&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852762	252149337							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287779	CC(Cc1ccncc1)c1nc2cc(C)c(C)cc2n1Cc1ccc(Cl)cc1	InChI=1S/C24H24ClN3/c1-16-13-22-23(14-17(16)2)28(15-20-4-6-21(25)7-5-20)24(27-22)18(3)12-19-8-10-26-11-9-19/h4-11,13-14,18H,12,15H2,1-3H3	BLGMRTIAYIXMRH-UHFFFAOYSA-N	149383	US8975247, EBP461	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8800							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149383&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46936110	252149338							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287780	Cc1cc2nc(CC3CCCNC3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H26ClN3/c1-15-10-20-21(11-16(15)2)26(14-17-5-7-19(23)8-6-17)22(25-20)12-18-4-3-9-24-13-18/h5-8,10-11,18,24H,3-4,9,12-14H2,1-2H3	LLYGWWMPKYKZGL-UHFFFAOYSA-N	149384	US8975247, EBP660	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 490							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149384&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852720	252149339							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287781	Cc1cc2nc(CC3CCCCC3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C23H27ClN2/c1-16-12-21-22(13-17(16)2)26(15-19-8-10-20(24)11-9-19)23(25-21)14-18-6-4-3-5-7-18/h8-13,18H,3-7,14-15H2,1-2H3	POLITEGQHLSZOD-UHFFFAOYSA-N	149385	US8975247, EBP468	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149385&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852724	252149340							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287782	CN1CCCC1CCc1nc2cc(C)c(C)cc2n1Cc1ccc(Cl)cc1	InChI=1S/C23H28ClN3/c1-16-13-21-22(14-17(16)2)27(15-18-6-8-19(24)9-7-18)23(25-21)11-10-20-5-4-12-26(20)3/h6-9,13-14,20H,4-5,10-12,15H2,1-3H3	VYSFWHXSTDCNEA-UHFFFAOYSA-N	149386	US8975247, EBP661	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 260							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149386	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149386&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852722	252149341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287783	Cc1cc2nc(\C=C\c3cccs3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H19ClN2S/c1-15-12-20-21(13-16(15)2)25(14-17-5-7-18(23)8-6-17)22(24-20)10-9-19-4-3-11-26-19/h3-13H,14H2,1-2H3	GEOVPKLJJUEMHI-UHFFFAOYSA-N	149387	US8975247, EBP475	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149387&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852736	252149342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287784	C[C@H]1CCCN1Cc1nc2cc(C)ccc2n1Cc1ccc(Cl)cc1 |r|	InChI=1S/C21H24ClN3/c1-15-5-10-20-19(12-15)23-21(14-24-11-3-4-16(24)2)25(20)13-17-6-8-18(22)9-7-17/h5-10,12,16H,3-4,11,13-14H2,1-2H3	BGOQZZKCJFWGFF-UHFFFAOYSA-N	149388	US8975247, EBP315	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<1000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149388	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149388&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			59172158	252149343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287785	C\C(=C/c1cccnc1)c1nc2cc(C)c(C)cc2n1Cc1ccc(Cl)cc1	InChI=1S/C24H22ClN3/c1-16-12-22-23(13-17(16)2)28(15-19-6-8-21(25)9-7-19)24(27-22)18(3)11-20-5-4-10-26-14-20/h4-14H,15H2,1-3H3	MXQTZBCTXYVYLZ-UHFFFAOYSA-N	149389	US8975247, EBP462	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149389	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149389&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852735	252149344							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287786	Cc1cc2nc(COC3CCCC3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H25ClN2O/c1-15-11-20-21(12-16(15)2)25(13-17-7-9-18(23)10-8-17)22(24-20)14-26-19-5-3-4-6-19/h7-12,19H,3-6,13-14H2,1-2H3	YYLDXROODQIWGP-UHFFFAOYSA-N	149390	US8975247, EBP325	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149390	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149390&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852737	252149345							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287787	Cc1cc2ncn(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C16H15ClN2/c1-11-7-15-16(8-12(11)2)19(10-18-15)9-13-3-5-14(17)6-4-13/h3-8,10H,9H2,1-2H3	AGMQHEBJQCVRFK-UHFFFAOYSA-N	50447261	CHEMBL1945694	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50447261	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50447261&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			683409	194945157		CHEMBL1945694					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287788	Clc1ccc(Cn2c(nc3cc(Cl)c(Cl)cc23)-c2ccc(=O)[nH]c2)cc1Cl	InChI=1S/C19H11Cl4N3O/c20-12-3-1-10(5-13(12)21)9-26-17-7-15(23)14(22)6-16(17)25-19(26)11-2-4-18(27)24-8-11/h1-8H,9H2,(H,24,27)	VNRLFXIUGYIZQF-UHFFFAOYSA-N	149391	US8975247, EBP106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149391	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149391&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			91825550	252149346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287789	Cc1cc2nc(\C=C\c3ccccc3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C24H21ClN2/c1-17-14-22-23(15-18(17)2)27(16-20-8-11-21(25)12-9-20)24(26-22)13-10-19-6-4-3-5-7-19/h3-15H,16H2,1-2H3	DFNPOFPUTAASIC-UHFFFAOYSA-N	149392	US8975247, EBP101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149392	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149392&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			5919832	252149347							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287790	c1ccc2c(c1)nc(n2Cc3ccc(cc3)Cl)CN4CCCC4	InChI=1S/C19H20ClN3/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22/h1-2,5-10H,3-4,11-14H2	CJXAEXPPLWQRFR-UHFFFAOYSA-N	85747	CLEMIZOLE HYDROCHLORIDE::NSC_2782::CAS_442-52-4::clemizole	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<1000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85747	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85747&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	GX0	7D4P	2782	136351847							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287791	Clc1ccc(Cn2c(CN3CCCC3=O)nc3ccccc23)cc1	InChI=1S/C19H18ClN3O/c20-15-9-7-14(8-10-15)12-23-17-5-2-1-4-16(17)21-18(23)13-22-11-3-6-19(22)24/h1-2,4-5,7-10H,3,6,11-13H2	BELFTQXCFIPCTM-UHFFFAOYSA-N	149393	US8975247, EBP144	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149393	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149393&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			14070366	252149348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287792	COc1ccc(Cn2cnc3c(NS(C)(=O)=O)c(C)c(C)cc23)cc1	InChI=1S/C18H21N3O3S/c1-12-9-16-18(17(13(12)2)20-25(4,22)23)19-11-21(16)10-14-5-7-15(24-3)8-6-14/h5-9,11,20H,10H2,1-4H3	XKFHHOBYJADYLZ-UHFFFAOYSA-N	61806	N-[1-(4-methoxybenzyl)-5,6-dimethyl-1H-1,3-benzimidazol-4-yl]methanesulfonamide::cid_1479154::SMR000168555::N-[1-[(4-methoxyphenyl)methyl]-5,6-dimethyl-benzimidazol-4-yl]methanesulfonamide::MLS000328049::N-[1-[(4-methoxyphenyl)methyl]-5,6-dimethylbenzimidazol-4-yl]methanesulfonamide::N-[1-[(4-methoxyphenyl)methyl]-5,6-dimethyl-4-benzimidazolyl]methanesulfonamide::N-(5,6-dimethyl-1-p-anisyl-benzimidazol-4-yl)methanesulfonamide	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61806&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			1479154	252640958							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287793	CS(=O)(=O)c1ccc2n(Cc3ccccc3)c(nc2c1)C(F)(F)F	InChI=1S/C16H13F3N2O2S/c1-24(22,23)12-7-8-14-13(9-12)20-15(16(17,18)19)21(14)10-11-5-3-2-4-6-11/h2-9H,10H2,1H3	RWERGVFMCDHOAG-UHFFFAOYSA-N	149394	US8975247, EBP108	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149394	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149394&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			4548877	252149349							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287794	Cc1cc2nc(CC3CCCC3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H25ClN2/c1-15-11-20-21(12-16(15)2)25(14-18-7-9-19(23)10-8-18)22(24-20)13-17-5-3-4-6-17/h7-12,17H,3-6,13-14H2,1-2H3	CVGFDACBJVOANI-UHFFFAOYSA-N	149395	US8975247, EBP271	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1300							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149395	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149395&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			59172143	252149350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287795	OC[C@@H]1CCCN1Cc1nc2ccccc2n1Cc1ccc(Cl)cc1 |r|	InChI=1S/C20H22ClN3O/c21-16-9-7-15(8-10-16)12-24-19-6-2-1-5-18(19)22-20(24)13-23-11-3-4-17(23)14-25/h1-2,5-10,17,25H,3-4,11-14H2	DNVVPFZYKKHGFR-UHFFFAOYSA-N	149396	US8975247, EBP163	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<1000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149396	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149396&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46936063	252149351							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287796	Cc1cc2nc(\C=C\c3ccco3)n(Cc3ccc(Cl)cc3)c2cc1C	InChI=1S/C22H19ClN2O/c1-15-12-20-21(13-16(15)2)25(14-17-5-7-18(23)8-6-17)22(24-20)10-9-19-4-3-11-26-19/h3-13H,14H2,1-2H3	LFMQZZANROCXPM-UHFFFAOYSA-N	149397	US8975247, EBP376	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149397	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149397&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852989	252149352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287797	COc1ccc2nc(CN3CCC[C@H]3CO)n(Cc3ccc(Cl)cc3)c2c1 |r|	InChI=1S/C21H24ClN3O2/c1-27-18-8-9-19-20(11-18)25(12-15-4-6-16(22)7-5-15)21(23-19)13-24-10-2-3-17(24)14-26/h4-9,11,17,26H,2-3,10,12-14H2,1H3	LVPMIHVTBWZBAF-UHFFFAOYSA-N	149398	US8975247, EBP484	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149398	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149398&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70852835	252149353							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287798	OCc1nc2ccccc2n1Cc1ccc(Cl)cc1	InChI=1S/C15H13ClN2O/c16-12-7-5-11(6-8-12)9-18-14-4-2-1-3-13(14)17-15(18)10-19/h1-8,19H,9-10H2	VUZVSFJBGRTRQC-UHFFFAOYSA-N	149399	US8975247, EBP143	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149399	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149399&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			743896	252149354							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
287799	Cc1ccc2nc(CN3CCCC3)n(Cc3ccc(Cl)cc3)c2c1	InChI=1S/C20H22ClN3/c1-15-4-9-18-19(12-15)24(13-16-5-7-17(21)8-6-16)20(22-18)14-23-10-2-3-11-23/h4-9,12H,2-3,10-11,13-14H2,1H3	AXXKVCHIEONWSF-UHFFFAOYSA-N	149400	US8975247, EBP425	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 650							US Patent		10.7270/Q26M35J2		aid1800955	US8975247	Choong, IC; Cory, D; Glenn, JS; Yang, W	3/10/2015	8/3/2015	The Board of Trustees of The Leland Stanford Junion University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149400&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70936730	252149355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288635	COCc1cnn(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:28|	InChI=1S/C21H24N4O4/c1-26-10-14-8-23-25(9-14)15-3-4-17-16(7-15)21(13-28-18(22)24-21)19(11-27-12-19)20(29-17)5-2-6-20/h3-4,7-9H,2,5-6,10-13H2,1H3,(H2,22,24)	NRTIHHVWKLDASP-UHFFFAOYSA-N	149718	US8975415, RP4::US9242973, RP4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149718	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149718&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90055955	252159262							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288636	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C20H20N4O3/c21-17-24-20(11-26-17)15-6-13(14-7-22-12-23-8-14)2-3-16(15)27-19(4-1-5-19)18(20)9-25-10-18/h2-3,6-8,12H,1,4-5,9-11H2,(H2,21,24)	APMDRJOSPMXZBV-UHFFFAOYSA-N	149719	US8975415, RP5::US9242973, RP5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149719&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246703	252159263							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288637	CC1(C)Oc2ccc(Br)cc2C2(COC(N)=N2)C11COC1 |c:16|	InChI=1S/C15H17BrN2O3/c1-13(2)14(6-19-7-14)15(8-20-12(17)18-15)10-5-9(16)3-4-11(10)21-13/h3-5H,6-8H2,1-2H3,(H2,17,18)	BFCFOLFRUMYREH-UHFFFAOYSA-N	149720	US8975415, RP6::US9242973, RP6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149720	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149720&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724229	252159264							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288638	CCC1Oc2ccc(Br)cc2C2(COC(N)=N2)C11COC1 |c:16|	InChI=1S/C15H17BrN2O3/c1-2-12-14(6-19-7-14)15(8-20-13(17)18-15)10-5-9(16)3-4-11(10)21-12/h3-5,12H,2,6-8H2,1H3,(H2,17,18)	UVKPJIHODHUWCZ-UHFFFAOYSA-N	149724	US8975415, RP9b::US8975415, RP9a::US9242973, RP9b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149724&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056181	252159268							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288639	CCC1Oc2ccc(Br)cc2C2(COC(N)=N2)C11COC1 |c:16|	InChI=1S/C15H17BrN2O3/c1-2-12-14(6-19-7-14)15(8-20-13(17)18-15)10-5-9(16)3-4-11(10)21-12/h3-5,12H,2,6-8H2,1H3,(H2,17,18)	UVKPJIHODHUWCZ-UHFFFAOYSA-N	149724	US8975415, RP9b::US8975415, RP9a::US9242973, RP9b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149724	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149724&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056181	252159268							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288640	NC1=NC2(CO1)c1cc(Br)ccc1OC1(CCCC1)C21COC1 |t:1|	InChI=1S/C17H19BrN2O3/c18-11-3-4-13-12(7-11)17(10-22-14(19)20-17)15(8-21-9-15)16(23-13)5-1-2-6-16/h3-4,7H,1-2,5-6,8-10H2,(H2,19,20)	DTJVAANWMRFEEX-UHFFFAOYSA-N	149726	US8975415, RP10::US9242973, RP10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149726&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056183	252159269							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288641	NC1=NC2(CO1)c1cc(Br)ccc1OC(Cc1ccccc1)C21COC1 |t:1|	InChI=1S/C20H19BrN2O3/c21-14-6-7-16-15(9-14)20(12-25-18(22)23-20)19(10-24-11-19)17(26-16)8-13-4-2-1-3-5-13/h1-7,9,17H,8,10-12H2,(H2,22,23)	GSLXZIRPXIIFQZ-UHFFFAOYSA-N	149735	US8975415, RP15b::US8975415, RP15a::US9242973, RP15b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149735&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056190	252159274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288642	NC1=NC2(CO1)c1cc(Br)ccc1OC(Cc1ccccc1)C21COC1 |t:1|	InChI=1S/C20H19BrN2O3/c21-14-6-7-16-15(9-14)20(12-25-18(22)23-20)19(10-24-11-19)17(26-16)8-13-4-2-1-3-5-13/h1-7,9,17H,8,10-12H2,(H2,22,23)	GSLXZIRPXIIFQZ-UHFFFAOYSA-N	149735	US8975415, RP15b::US8975415, RP15a::US9242973, RP15b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7930						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149735	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149735&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056190	252159274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288643	NC1=NC2(CO1)c1cc(Br)ccc1OC(CC1CC1)C21COC1 |t:1|	InChI=1S/C17H19BrN2O3/c18-11-3-4-13-12(6-11)17(9-22-15(19)20-17)16(7-21-8-16)14(23-13)5-10-1-2-10/h3-4,6,10,14H,1-2,5,7-9H2,(H2,19,20)	FKWYDOXONAHPDE-UHFFFAOYSA-N	149737	US8975415, RP16b::US8975415, RP16a::US9242973, RP16b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149737&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056184	252159275							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288644	NC1=NC2(CO1)c1cc(Br)ccc1OC(CC1CC1)C21COC1 |t:1|	InChI=1S/C17H19BrN2O3/c18-11-3-4-13-12(6-11)17(9-22-15(19)20-17)16(7-21-8-16)14(23-13)5-10-1-2-10/h3-4,6,10,14H,1-2,5,7-9H2,(H2,19,20)	FKWYDOXONAHPDE-UHFFFAOYSA-N	149737	US8975415, RP16b::US8975415, RP16a::US9242973, RP16b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149737	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149737&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056184	252159275							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288645	NC1=NC2(CO1)c1cc(Br)ccc1OCC21CC1 |t:1|	InChI=1S/C13H13BrN2O2/c14-8-1-2-10-9(5-8)13(7-18-11(15)16-13)12(3-4-12)6-17-10/h1-2,5H,3-4,6-7H2,(H2,15,16)	PRFPBWPICIUVRO-UHFFFAOYSA-N	149739	US8975415, RP17::US9242973, RP17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724231	252159276							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288646	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2C2(COC(N)=N2)C11COC1 |c:26|	InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	INWIVMOTHPFWNU-UHFFFAOYSA-N	149749	US8975415, 27::US9242973, 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149749	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149749&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548694	252159286							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288647	CC1(C)Oc2ccc(NC(=O)c3ccc(F)cn3)cc2C2(COC(N)=N2)C11COC1 |c:26|	InChI=1S/C21H21FN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	FSJTVQBTRXXXMC-UHFFFAOYSA-N	149750	US8975415, 28::US9242973, 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548695	252159287							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288648	NC1=NC2(CO1)c1cc(NC(=O)c3ncc(Cl)cc3F)ccc1OCC21CC1 |t:1|	InChI=1S/C19H16ClFN4O3/c20-10-5-13(21)15(23-7-10)16(26)24-11-1-2-14-12(6-11)19(9-28-17(22)25-19)18(3-4-18)8-27-14/h1-2,5-7H,3-4,8-9H2,(H2,22,25)(H,24,26)	BAZZVTQQQIAGLD-UHFFFAOYSA-N	149751	US8975415, RP29::US9242973, RP29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149751	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056150	252159288							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288649	CC1(C)Oc2ccc(NC(=O)c3ncc(Cl)cc3F)cc2C2(COC(N)=N2)C11COC1 |c:27|	InChI=1S/C21H20ClFN4O4/c1-19(2)20(8-29-9-20)21(10-30-18(24)27-21)13-6-12(3-4-15(13)31-19)26-17(28)16-14(23)5-11(22)7-25-16/h3-7H,8-10H2,1-2H3,(H2,24,27)(H,26,28)	NNCFJTIUQAEALJ-UHFFFAOYSA-N	149752	US8975415, 30::US9242973, 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149752	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548696	252159289							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288650	NC1=NC2(CO1)c1cc(NC(=O)c3ccc(F)cn3)ccc1OCC21CC1 |t:1|	InChI=1S/C19H17FN4O3/c20-11-1-3-14(22-8-11)16(25)23-12-2-4-15-13(7-12)19(10-27-17(21)24-19)18(5-6-18)9-26-15/h1-4,7-8H,5-6,9-10H2,(H2,21,24)(H,23,25)	SGURBDAGQXAXNV-UHFFFAOYSA-N	149753	US8975415, RP31::US9242973, RP31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149753	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149753&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724294	252159290							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288651	NC1=NC2(CO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1OCC21CC1 |t:1|	InChI=1S/C19H17ClN4O3/c20-11-1-3-14(22-8-11)16(25)23-12-2-4-15-13(7-12)19(10-27-17(21)24-19)18(5-6-18)9-26-15/h1-4,7-8H,5-6,9-10H2,(H2,21,24)(H,23,25)	ASXIBZVBBQRBMI-UHFFFAOYSA-N	149754	US8975415, RP32::US9242973, RP32	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2170						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149754	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149754&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056233	252159291							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288652	NC1=NC2(CO1)c1cc(ccc1OCC21COC1)-c1cc(Cl)cnc1F |t:1|	InChI=1S/C18H15ClFN3O3/c19-11-4-12(15(20)22-5-11)10-1-2-14-13(3-10)18(9-26-16(21)23-18)17(8-25-14)6-24-7-17/h1-5H,6-9H2,(H2,21,23)	OXWANDFSWNCOLM-UHFFFAOYSA-N	149756	US8975415, RP34::US9242973, RP34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149756	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149756&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246706	252159293							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288653	CC1(C)Oc2ccc(Br)cc2C2(CSC(N)=N2)C11COC1 |c:16|	InChI=1S/C15H17BrN2O2S/c1-13(2)14(6-19-7-14)15(8-21-12(17)18-15)10-5-9(16)3-4-11(10)20-13/h3-5H,6-8H2,1-2H3,(H2,17,18)	FXWBDJSWBRAHBD-UHFFFAOYSA-N	149763	US8975415, RP42::US9242973, RP42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149763	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149763&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056326	252159300							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288654	NC1=NC2(CO1)c1cc(Nc3ncccc3Cl)ccc1OCC21COC1 |t:1|	InChI=1S/C18H17ClN4O3/c19-13-2-1-5-21-15(13)22-11-3-4-14-12(6-11)18(10-26-16(20)23-18)17(9-25-14)7-24-8-17/h1-6H,7-10H2,(H2,20,23)(H,21,22)	XNPBNQHTEMDPQV-UHFFFAOYSA-N	149764	US8975415, RP43::US9242973, RP43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149764&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724298	252159301							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288655	COc1cccnc1Nc1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:29|	InChI=1S/C22H24N4O4/c1-27-17-4-2-9-24-18(17)25-14-5-6-16-15(10-14)22(13-29-19(23)26-22)20(11-28-12-20)21(30-16)7-3-8-21/h2,4-6,9-10H,3,7-8,11-13H2,1H3,(H2,23,26)(H,24,25)	WWHBQSJSWHAQSI-UHFFFAOYSA-N	149766	US8975415, RP45::US9242973, RP45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149766&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056328	252159303							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288656	CC(C)Cc1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:23|	InChI=1S/C20H26N2O3/c1-13(2)8-14-4-5-16-15(9-14)20(12-24-17(21)22-20)18(10-23-11-18)19(25-16)6-3-7-19/h4-5,9,13H,3,6-8,10-12H2,1-2H3,(H2,21,22)	DRTDEDKNDXQLDZ-UHFFFAOYSA-N	149767	US8975415, RP46::US9242973, RP46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149767	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149767&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724299	252159304							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288657	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:15|	InChI=1S/C19H20N4O3/c1-17(2)18(8-24-9-18)19(10-25-16(20)23-19)14-5-12(3-4-15(14)26-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	WRPYZOUQPVZQFZ-UHFFFAOYSA-N	149770	US8975415, RP69::US8975415, RP51b::US8975415, RP51a::US9242973, RP69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025104	252159307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288658	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:15|	InChI=1S/C19H20N4O3/c1-17(2)18(8-24-9-18)19(10-25-16(20)23-19)14-5-12(3-4-15(14)26-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	WRPYZOUQPVZQFZ-UHFFFAOYSA-N	149770	US8975415, RP69::US8975415, RP51b::US8975415, RP51a::US9242973, RP69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025104	252159307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288659	CC#Cc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:24|	InChI=1S/C21H19N3O2/c1-2-3-14-8-16(11-23-10-14)15-4-5-18-17(9-15)21(13-26-19(22)24-21)20(6-7-20)12-25-18/h4-5,8-11H,6-7,12-13H2,1H3,(H2,22,24)	ZKVKPYPCNDJJIH-UHFFFAOYSA-N	149772	US8975415, RP111::US8975415, RP52a::US9242973, RP111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4830						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90016739	252159308							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288660	CC#Cc1cncc(c1)-c1ccc2OCC3(COC3)C3(COC(N)=N3)c2c1 |c:25|	InChI=1S/C21H19N3O3/c1-2-3-14-6-16(9-23-8-14)15-4-5-18-17(7-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	KPXCLUUQECRYFF-UHFFFAOYSA-N	149773	US8975415, RP108::US8975415, RP53b::US9242973, RP108	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724311	252159309							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288661	CC1(C)Oc2ccc(cc2C2(CSC(N)=N2)C11COC1)-c1cncnc1 |c:15|	InChI=1S/C19H20N4O2S/c1-17(2)18(8-24-9-18)19(10-26-16(20)23-19)14-5-12(3-4-15(14)25-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	DGIBRPPLNYXLMV-UHFFFAOYSA-N	149774	US8975415, RP54::US9242973, RP54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724304	252159310							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288662	CC#Cc1ccnc(c1)-c1ccc2OCC3(COC3)C3(COC(N)=N3)c2c1 |c:25|	InChI=1S/C21H19N3O3/c1-2-3-14-6-7-23-17(8-14)15-4-5-18-16(9-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	FONNNDYVWDWHRD-UHFFFAOYSA-N	149775	US8975415, RP56::US9242973, RP56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149775	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149775&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90055131	252159311							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288663	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(c1)C1CC1 |t:1|	InChI=1S/C21H21N3O2/c22-19-24-21(12-26-19)17-8-14(3-4-18(17)25-11-20(21)5-6-20)16-7-15(9-23-10-16)13-1-2-13/h3-4,7-10,13H,1-2,5-6,11-12H2,(H2,22,24)	DFEWHEYFZREFMD-UHFFFAOYSA-N	149776	US8975415, RP57::US9242973, RP57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3480						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149776&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246708	252159312							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288664	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OCC(F)(F)F)c1 |t:1|	InChI=1S/C20H18F3N3O3/c21-20(22,23)11-27-14-5-13(7-25-8-14)12-1-2-16-15(6-12)19(10-29-17(24)26-19)18(3-4-18)9-28-16/h1-2,5-8H,3-4,9-11H2,(H2,24,26)	PBIVNBDJISSSOF-UHFFFAOYSA-N	149777	US8975415, RP58::US9242973, RP58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5810						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149777&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246709	252159313							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288665	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OCC(F)F)c1 |t:1|	InChI=1S/C20H19F2N3O3/c21-17(22)9-26-14-5-13(7-24-8-14)12-1-2-16-15(6-12)20(11-28-18(23)25-20)19(3-4-19)10-27-16/h1-2,5-8,17H,3-4,9-11H2,(H2,23,25)	WQKBRYBBAYLSSQ-UHFFFAOYSA-N	149778	US8975415, RP59::US9242973, RP59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6900						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149778&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246710	252159314							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288666	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OC(F)F)c1 |t:1|	InChI=1S/C19H17F2N3O3/c20-16(21)27-13-5-12(7-23-8-13)11-1-2-15-14(6-11)19(10-26-17(22)24-19)18(3-4-18)9-25-15/h1-2,5-8,16H,3-4,9-10H2,(H2,22,24)	UNYXJDJEOAZPJZ-UHFFFAOYSA-N	149779	US8975415, RP60::US9242973, RP60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2780						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149779&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90055135	252159315							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288667	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cnc2[nH]ccc2c1 |t:1|	InChI=1S/C20H18N4O2/c21-18-24-20(11-26-18)15-8-12(1-2-16(15)25-10-19(20)4-5-19)14-7-13-3-6-22-17(13)23-9-14/h1-3,6-9H,4-5,10-11H2,(H2,21,24)(H,22,23)	WAWSJFFWUYSZHD-UHFFFAOYSA-N	149780	US8975415, RP61::US9242973, RP61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9220						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149780&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724307	252159316							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288668	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cnc2[nH]cc(Cl)c2c1 |t:1|	InChI=1S/C20H17ClN4O2/c21-15-8-24-17-13(15)5-12(7-23-17)11-1-2-16-14(6-11)20(10-27-18(22)25-20)19(3-4-19)9-26-16/h1-2,5-8H,3-4,9-10H2,(H2,22,25)(H,23,24)	OJCJILDVNFWSDR-UHFFFAOYSA-N	149781	US8975415, RP62::US9242973, RP62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4430						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149781	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149781&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90249017	252159317							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288669	CCc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:23|	InChI=1S/C20H21N3O2/c1-2-13-7-15(10-22-9-13)14-3-4-17-16(8-14)20(12-25-18(21)23-20)19(5-6-19)11-24-17/h3-4,7-10H,2,5-6,11-12H2,1H3,(H2,21,23)	ACFKJXYIJBZGDF-UHFFFAOYSA-N	149782	US8975415, RP63::US9242973, RP63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4480						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149782	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149782&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246712	252159318							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288670	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OCC(F)(F)C(F)F)c1 |t:1|	InChI=1S/C21H19F4N3O3/c22-17(23)21(24,25)11-29-14-5-13(7-27-8-14)12-1-2-16-15(6-12)20(10-31-18(26)28-20)19(3-4-19)9-30-16/h1-2,5-8,17H,3-4,9-11H2,(H2,26,28)	DSXZHBCAGPUTHY-UHFFFAOYSA-N	149783	US8975415, RP64::US9242973, RP64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1670						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149783	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149783&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246711	252159319							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288671	COc1ccnc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:26|	InChI=1S/C21H23N3O4/c1-19(2)20(10-26-11-20)21(12-27-18(22)24-21)15-8-13(4-5-17(15)28-19)16-9-14(25-3)6-7-23-16/h4-9H,10-12H2,1-3H3,(H2,22,24)	VODDOGVAQARPID-UHFFFAOYSA-N	149784	US8975415, RP65::US9242973, RP65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9770						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149784&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724309	252159320							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288672	Cc1cn2ccc(cc2n1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:31|	InChI=1S/C24H24N4O3/c1-15-11-28-8-5-17(10-20(28)26-15)16-3-4-19-18(9-16)24(14-30-21(25)27-24)22(12-29-13-22)23(31-19)6-2-7-23/h3-5,8-11H,2,6-7,12-14H2,1H3,(H2,25,27)	YXGIXUOSNXEEFY-UHFFFAOYSA-N	149785	US8975415, RP66::US9242973, RP66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056473	252159321							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288673	Cc1cn2cc(ccc2n1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:31|	InChI=1S/C24H24N4O3/c1-15-10-28-11-17(4-6-20(28)26-15)16-3-5-19-18(9-16)24(14-30-21(25)27-24)22(12-29-13-22)23(31-19)7-2-8-23/h3-6,9-11H,2,7-8,12-14H2,1H3,(H2,25,27)	JKGOTVHTXJKXLS-UHFFFAOYSA-N	149786	US8975415, RP67::US9242973, RP67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90017611	252159322							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288674	CC#Cc1cncc(c1)-c1ccc2OCC3(COC3)C3(CSC(N)=N3)c2c1 |c:25|	InChI=1S/C21H19N3O2S/c1-2-3-14-6-16(9-23-8-14)15-4-5-18-17(7-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	SUTVFEFTMJCRDP-UHFFFAOYSA-N	149787	US8975415, RP68::US9242973, RP68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6050						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149787&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246713	252159323							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288675	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:15|	InChI=1S/C19H20N4O3/c1-17(2)18(8-24-9-18)19(10-25-16(20)23-19)14-5-12(3-4-15(14)26-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	WRPYZOUQPVZQFZ-UHFFFAOYSA-N	149770	US8975415, RP69::US8975415, RP51b::US8975415, RP51a::US9242973, RP69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025104	252159307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288676	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc(F)c1 |t:1|	InChI=1S/C21H20FN3O3/c22-15-6-14(8-24-9-15)13-2-3-17-16(7-13)21(12-27-18(23)25-21)19(10-26-11-19)20(28-17)4-1-5-20/h2-3,6-9H,1,4-5,10-12H2,(H2,23,25)	VKXZBNSASBAXPO-UHFFFAOYSA-N	149789	US8975415, RP70::US9242973, RP70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246714	252159324							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288677	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1F |t:1|	InChI=1S/C21H20FN3O3/c22-17-14(3-1-8-24-17)13-4-5-16-15(9-13)21(12-27-18(23)25-21)19(10-26-11-19)20(28-16)6-2-7-20/h1,3-5,8-9H,2,6-7,10-12H2,(H2,23,25)	MIWGEPYDEJPCPW-UHFFFAOYSA-N	149790	US8975415, RP71::US9242973, RP71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149790&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246716	252159325							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288678	COc1cncc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:28|	InChI=1S/C22H23N3O4/c1-26-16-7-15(9-24-10-16)14-3-4-18-17(8-14)22(13-28-19(23)25-22)20(11-27-12-20)21(29-18)5-2-6-21/h3-4,7-10H,2,5-6,11-13H2,1H3,(H2,23,25)	OKGLRFINLNSCOR-UHFFFAOYSA-N	149791	US8975415, RP72::US9242973, RP72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8220						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149791&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246715	252159326							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288679	Cc1cncc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:27|	InChI=1S/C22H23N3O3/c1-14-7-16(10-24-9-14)15-3-4-18-17(8-15)22(13-27-19(23)25-22)20(11-26-12-20)21(28-18)5-2-6-21/h3-4,7-10H,2,5-6,11-13H2,1H3,(H2,23,25)	XVSNEAWVASTHHT-UHFFFAOYSA-N	149794	US8975415, RP75::US9242973, RP75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149794&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025147	252159329							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288680	Cc1cnnc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:27|	InChI=1S/C21H22N4O3/c1-13-7-16(25-23-9-13)14-3-4-17-15(8-14)21(12-27-18(22)24-21)19(10-26-11-19)20(28-17)5-2-6-20/h3-4,7-9H,2,5-6,10-12H2,1H3,(H2,22,24)	CENZKPKDVOYGAD-UHFFFAOYSA-N	149795	US8975415, RP76::US9242973, RP76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149795&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246718	252159330							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288681	C[C@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cccnc1F |r,c:14|	InChI=1S/C19H18FN3O3/c1-11-18(8-24-9-18)19(10-25-17(21)23-19)14-7-12(4-5-15(14)26-11)13-3-2-6-22-16(13)20/h2-7,11H,8-10H2,1H3,(H2,21,23)	GBWBGGRZIJBHOV-UHFFFAOYSA-N	149796	US8975415, RP77::US9242973, RP77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149796&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246719	252159331							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288682	C[C@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cncnc1 |r,c:14|	InChI=1S/C18H18N4O3/c1-11-17(7-23-8-17)18(9-24-16(19)22-18)14-4-12(2-3-15(14)25-11)13-5-20-10-21-6-13/h2-6,10-11H,7-9H2,1H3,(H2,19,22)	VFWRHIJUHBWEBW-UHFFFAOYSA-N	149797	US8975415, RP78::US9242973, RP78	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149797&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056135	252159332							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288683	C[C@@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cccnc1F |r,c:14|	InChI=1S/C19H18FN3O3/c1-11-18(8-24-9-18)19(10-25-17(21)23-19)14-7-12(4-5-15(14)26-11)13-3-2-6-22-16(13)20/h2-7,11H,8-10H2,1H3,(H2,21,23)	GBWBGGRZIJBHOV-UHFFFAOYSA-N	149798	US8975415, RP79::US9242973, RP79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149798&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056142	252159333							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288684	C[C@@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cncnc1 |r,c:14|	InChI=1S/C18H18N4O3/c1-11-17(7-23-8-17)18(9-24-16(19)22-18)14-4-12(2-3-15(14)25-11)13-5-20-10-21-6-13/h2-6,10-11H,7-9H2,1H3,(H2,19,22)	VFWRHIJUHBWEBW-UHFFFAOYSA-N	149799	US8975415, RP80::US9242973, RP80	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149799&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056134	252159334							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288685	COc1cncc(c1)-c1ccc2O[C@H](C)C3(COC3)[C@]3(COC(N)=N3)c2c1 |r,c:25|	InChI=1S/C20H21N3O4/c1-12-19(9-25-10-19)20(11-26-18(21)23-20)16-6-13(3-4-17(16)27-12)14-5-15(24-2)8-22-7-14/h3-8,12H,9-11H2,1-2H3,(H2,21,23)	FODVISLDJAALAH-UHFFFAOYSA-N	149800	US8975415, RP81::US9242973, RP81	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149800&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246720	252159335							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288686	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cccnc1F |c:15|	InChI=1S/C20H20FN3O3/c1-18(2)19(9-25-10-19)20(11-26-17(22)24-20)14-8-12(5-6-15(14)27-18)13-4-3-7-23-16(13)21/h3-8H,9-11H2,1-2H3,(H2,22,24)	AVGCDLOTQSAMEY-UHFFFAOYSA-N	149801	US8975415, RP82::US9242973, RP82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149801&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246721	252159336							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288687	COc1cncc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:26|	InChI=1S/C21H23N3O4/c1-19(2)20(10-26-11-20)21(12-27-18(22)24-21)16-7-13(4-5-17(16)28-19)14-6-15(25-3)9-23-8-14/h4-9H,10-12H2,1-3H3,(H2,22,24)	IAWZSEUFAASPLV-UHFFFAOYSA-N	149802	US8975415, RP83::US9242973, RP83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149802&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246722	252159337							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288688	CCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:15|	InChI=1S/C19H20N4O3/c1-2-16-18(8-24-9-18)19(10-25-17(20)23-19)14-5-12(3-4-15(14)26-16)13-6-21-11-22-7-13/h3-7,11,16H,2,8-10H2,1H3,(H2,20,23)	ZMBYVIVIUYRASD-UHFFFAOYSA-N	149803	US8975415, RP87::US8975415, RP84::US9242973, RP84	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149803&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246723	252159338							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288689	NC1=NC2(CO1)c1cc(ccc1OC1(CCCC1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C21H22N4O3/c22-18-25-21(12-27-18)16-7-14(15-8-23-13-24-9-15)3-4-17(16)28-20(5-1-2-6-20)19(21)10-26-11-19/h3-4,7-9,13H,1-2,5-6,10-12H2,(H2,22,25)	STXYCGOXMYPZGQ-UHFFFAOYSA-N	149804	US8975415, RP85::US9242973, RP85	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149804&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056138	252159339							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288690	CCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#CC |c:15|	InChI=1S/C23H23N3O3/c1-3-5-15-8-17(11-25-10-15)16-6-7-19-18(9-16)23(14-28-21(24)26-23)22(12-27-13-22)20(4-2)29-19/h6-11,20H,4,12-14H2,1-2H3,(H2,24,26)	YOCKQJMJWGYCKD-UHFFFAOYSA-N	149805	US8975415, RP86::US9242973, RP86	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7940						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246724	252159340							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288691	NC1=NC2(CO1)c1cc(ccc1OC(C1CC1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C20H20N4O3/c21-18-24-20(10-26-18)15-5-13(14-6-22-11-23-7-14)3-4-16(15)27-17(12-1-2-12)19(20)8-25-9-19/h3-7,11-12,17H,1-2,8-10H2,(H2,21,24)	LHAFHTSWDCBCED-UHFFFAOYSA-N	149807	US8975415, RP89::US8975415, RP88::US9242973, RP89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056144	252159341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288692	NC1=NC2(CO1)c1cc(ccc1OC(C1CC1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C20H20N4O3/c21-18-24-20(10-26-18)15-5-13(14-6-22-11-23-7-14)3-4-16(15)27-17(12-1-2-12)19(20)8-25-9-19/h3-7,11-12,17H,1-2,8-10H2,(H2,21,24)	LHAFHTSWDCBCED-UHFFFAOYSA-N	149807	US8975415, RP89::US8975415, RP88::US9242973, RP89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056144	252159341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288693	CC(C)CC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:17|	InChI=1S/C21H24N4O3/c1-13(2)5-18-20(9-26-10-20)21(11-27-19(22)25-21)16-6-14(3-4-17(16)28-18)15-7-23-12-24-8-15/h3-4,6-8,12-13,18H,5,9-11H2,1-2H3,(H2,22,25)	QQPOTGIGKATGCB-UHFFFAOYSA-N	149809	US8975415, RP93::US8975415, RP90::US9242973, RP93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246725	252159342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288694	CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:16|	InChI=1S/C20H22N4O3/c1-2-3-17-19(9-25-10-19)20(11-26-18(21)24-20)15-6-13(4-5-16(15)27-17)14-7-22-12-23-8-14/h4-8,12,17H,2-3,9-11H2,1H3,(H2,21,24)	XGNRRAYBEHJJDH-UHFFFAOYSA-N	149810	US8975415, RP94::US8975415, RP91::US9242973, RP94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149810&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056255	252159343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288695	CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#CC |c:16|	InChI=1S/C24H25N3O3/c1-3-5-16-9-18(12-26-11-16)17-7-8-20-19(10-17)24(15-29-22(25)27-24)23(13-28-14-23)21(30-20)6-4-2/h7-12,21H,4,6,13-15H2,1-2H3,(H2,25,27)	VKNCKYKSIFQAIK-UHFFFAOYSA-N	149811	US8975415, RP92::US9242973, RP92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5340						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149811&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246726	252159344							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288696	CC(C)CC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:17|	InChI=1S/C21H24N4O3/c1-13(2)5-18-20(9-26-10-20)21(11-27-19(22)25-21)16-6-14(3-4-17(16)28-18)15-7-23-12-24-8-15/h3-4,6-8,12-13,18H,5,9-11H2,1-2H3,(H2,22,25)	QQPOTGIGKATGCB-UHFFFAOYSA-N	149809	US8975415, RP93::US8975415, RP90::US9242973, RP93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246725	252159342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288697	CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1 |c:16|	InChI=1S/C20H22N4O3/c1-2-3-17-19(9-25-10-19)20(11-26-18(21)24-20)15-6-13(4-5-16(15)27-17)14-7-22-12-23-8-14/h4-8,12,17H,2-3,9-11H2,1H3,(H2,21,24)	XGNRRAYBEHJJDH-UHFFFAOYSA-N	149810	US8975415, RP94::US8975415, RP91::US9242973, RP94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149810&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056255	252159343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288698	NC1=NC2(CO1)c1cc(ccc1OC(CCC(F)(F)F)C21CCC1)-c1cncnc1 |t:1|	InChI=1S/C21H21F3N4O2/c22-21(23,24)7-4-17-19(5-1-6-19)20(11-29-18(25)28-20)15-8-13(2-3-16(15)30-17)14-9-26-12-27-10-14/h2-3,8-10,12,17H,1,4-7,11H2,(H2,25,28)	DSTJFWHEXWTHCF-UHFFFAOYSA-N	149814	US8975415, RP95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149814&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246727	252159345							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288699	CC#Cc1cncc(c1)-c1ccc2OC(CCC(F)(F)F)C3(COC3)C3(COC(N)=N3)c2c1 |c:31|	InChI=1S/C24H22F3N3O3/c1-2-3-15-8-17(11-29-10-15)16-4-5-19-18(9-16)23(14-32-21(28)30-23)22(12-31-13-22)20(33-19)6-7-24(25,26)27/h4-5,8-11,20H,6-7,12-14H2,1H3,(H2,28,30)	LMEWGQSCAOBUKB-UHFFFAOYSA-N	149815	US8975415, RP96::US9242973, RP96	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149815&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246728	252159346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288700	NC1=NC2(CO1)c1cc(ccc1OCC21CCCO1)-c1cncnc1 |t:1|	InChI=1S/C18H18N4O3/c19-16-22-18(10-24-16)14-6-12(13-7-20-11-21-8-13)2-3-15(14)23-9-17(18)4-1-5-25-17/h2-3,6-8,11H,1,4-5,9-10H2,(H2,19,22)	DMEXFXDUGPEWQS-UHFFFAOYSA-N	149816	US8975415, RP98::US8975415, RP97::US9242973, RP98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149816&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246729	252159347							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288701	NC1=NC2(CO1)c1cc(ccc1OCC21CCCO1)-c1cncnc1 |t:1|	InChI=1S/C18H18N4O3/c19-16-22-18(10-24-16)14-6-12(13-7-20-11-21-8-13)2-3-15(14)23-9-17(18)4-1-5-25-17/h2-3,6-8,11H,1,4-5,9-10H2,(H2,19,22)	DMEXFXDUGPEWQS-UHFFFAOYSA-N	149816	US8975415, RP98::US8975415, RP97::US9242973, RP98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149816&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246729	252159347							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288702	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc(c1)C(F)(F)F |t:1|	InChI=1S/C22H20F3N3O3/c23-22(24,25)15-6-14(8-27-9-15)13-2-3-17-16(7-13)21(12-30-18(26)28-21)19(10-29-11-19)20(31-17)4-1-5-20/h2-3,6-9H,1,4-5,10-12H2,(H2,26,28)	DNXRXHBBOSWKEH-UHFFFAOYSA-N	149818	US8975415, RP99::US9242973, RP99	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149818&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056251	252159348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288703	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncnc1 |t:1|	InChI=1S/C17H16N4O2/c18-15-21-17(9-23-15)13-5-11(12-6-19-10-20-7-12)1-2-14(13)22-8-16(17)3-4-16/h1-2,5-7,10H,3-4,8-9H2,(H2,18,21)	GQFYFTNDSLXGAN-UHFFFAOYSA-N	149819	US8975415, RP100::US9242973, RP100	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149819&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056261	252159349							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288704	NC1=NC2(CO1)c1cc(ccc1OCC21CCC1)-c1cncnc1 |t:1|	InChI=1S/C18H18N4O2/c19-16-22-18(10-24-16)14-6-12(13-7-20-11-21-8-13)2-3-15(14)23-9-17(18)4-1-5-17/h2-3,6-8,11H,1,4-5,9-10H2,(H2,19,22)	AOHYTTMQYWIGBI-UHFFFAOYSA-N	149820	US8975415, RP101::US9242973, RP101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5280						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056252	252159350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288705	NC1=NC2(CO1)c1cc(c(F)cc1OCC21CC1)-c1cncnc1 |t:1|	InChI=1S/C17H15FN4O2/c18-13-4-14-12(3-11(13)10-5-20-9-21-6-10)17(8-24-15(19)22-17)16(1-2-16)7-23-14/h3-6,9H,1-2,7-8H2,(H2,19,22)	LZIPIZWOUYFZDB-UHFFFAOYSA-N	149821	US8975415, RP102::US9242973, RP102	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149821&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056259	252159351							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288706	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cccnc1F |t:1|	InChI=1S/C18H16FN3O2/c19-15-12(2-1-7-21-15)11-3-4-14-13(8-11)18(10-24-16(20)22-18)17(5-6-17)9-23-14/h1-4,7-8H,5-6,9-10H2,(H2,20,22)	HAVSLFQSSPEGTD-UHFFFAOYSA-N	149822	US8975415, RP103::US9242973, RP103	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149822&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056258	252159352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288707	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cc(Cl)cnc1F |t:1|	InChI=1S/C18H15ClFN3O2/c19-11-6-12(15(20)22-7-11)10-1-2-14-13(5-10)18(9-25-16(21)23-18)17(3-4-17)8-24-14/h1-2,5-7H,3-4,8-9H2,(H2,21,23)	YLFDDYWNYJPIAU-UHFFFAOYSA-N	149823	US8975415, RP104::US9242973, RP104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3250						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149823&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056260	252159353							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288708	COc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:23|	InChI=1S/C19H19N3O3/c1-23-14-6-13(8-21-9-14)12-2-3-16-15(7-12)19(11-25-17(20)22-19)18(4-5-18)10-24-16/h2-3,6-9H,4-5,10-11H2,1H3,(H2,20,22)	ZOGSWBUPTFGEHZ-UHFFFAOYSA-N	149824	US8975415, RP105::US9242973, RP105	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7900						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056199	252159354							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288709	CCOc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:24|	InChI=1S/C20H21N3O3/c1-2-24-15-7-14(9-22-10-15)13-3-4-17-16(8-13)20(12-26-18(21)23-20)19(5-6-19)11-25-17/h3-4,7-10H,2,5-6,11-12H2,1H3,(H2,21,23)	ZBXSCAQSUCUQMO-UHFFFAOYSA-N	149825	US8975415, RP106::US9242973, RP106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5750						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149825&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246730	252159355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288710	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(Cl)c1 |t:1|	InChI=1S/C18H16ClN3O2/c19-13-5-12(7-21-8-13)11-1-2-15-14(6-11)18(10-24-16(20)22-18)17(3-4-17)9-23-15/h1-2,5-8H,3-4,9-10H2,(H2,20,22)	WMZFHEUJJBBJRB-UHFFFAOYSA-N	149826	US8975415, RP107::US9242973, RP107	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2910						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149826&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056194	252159356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288711	CC#Cc1cncc(c1)-c1ccc2OCC3(COC3)C3(COC(N)=N3)c2c1 |c:25|	InChI=1S/C21H19N3O3/c1-2-3-14-6-16(9-23-8-14)15-4-5-18-17(7-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	KPXCLUUQECRYFF-UHFFFAOYSA-N	149773	US8975415, RP108::US8975415, RP53b::US9242973, RP108	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9400						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724311	252159309							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288712	CC#Cc1cncc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:29|	InChI=1S/C24H23N3O3/c1-2-4-16-9-18(12-26-11-16)17-5-6-20-19(10-17)24(15-29-21(25)27-24)22(13-28-14-22)23(30-20)7-3-8-23/h5-6,9-12H,3,7-8,13-15H2,1H3,(H2,25,27)	NPOSFNQEFRRESB-UHFFFAOYSA-N	149828	US8975415, RP109::US9242973, RP109	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246731	252159357							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288713	CC#Cc1cncc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:27|	InChI=1S/C23H23N3O3/c1-4-5-15-8-17(11-25-10-15)16-6-7-19-18(9-16)23(14-28-20(24)26-23)22(12-27-13-22)21(2,3)29-19/h6-11H,12-14H2,1-3H3,(H2,24,26)	TWNMFZUXTQLPDM-UHFFFAOYSA-N	149829	US8975415, RP110::US9242973, RP110	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149829&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056237	252159358							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288714	CC#Cc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:24|	InChI=1S/C21H19N3O2/c1-2-3-14-8-16(11-23-10-14)15-4-5-18-17(9-15)21(13-26-19(22)24-21)20(6-7-20)12-25-18/h4-5,8-11H,6-7,12-13H2,1H3,(H2,22,24)	ZKVKPYPCNDJJIH-UHFFFAOYSA-N	149772	US8975415, RP111::US8975415, RP52a::US9242973, RP111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1980						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90016739	252159308							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288715	CC#Cc1cncc(c1)-c1cc2c(OCC3(CC3)C22COC(N)=N2)cc1F |c:25|	InChI=1S/C21H18FN3O2/c1-2-3-13-6-14(10-24-9-13)15-7-16-18(8-17(15)22)26-11-20(4-5-20)21(16)12-27-19(23)25-21/h6-10H,4-5,11-12H2,1H3,(H2,23,25)	GYSSPZTVUHYMLA-UHFFFAOYSA-N	149831	US8975415, RP112::US9242973, RP112	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4320						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246732	252159359							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288716	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1C#N |t:1|	InChI=1S/C22H20N4O3/c23-10-17-15(3-1-8-25-17)14-4-5-18-16(9-14)22(13-28-19(24)26-22)20(11-27-12-20)21(29-18)6-2-7-21/h1,3-5,8-9H,2,6-7,11-13H2,(H2,24,26)	UGLJAYTUNCDFRY-UHFFFAOYSA-N	149834	US8975415, RP115::US9242973, RP115	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025658	252159362							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288717	Cc1cnc(F)c(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:28|	InChI=1S/C22H22FN3O3/c1-13-7-15(18(23)25-9-13)14-3-4-17-16(8-14)22(12-28-19(24)26-22)20(10-27-11-20)21(29-17)5-2-6-21/h3-4,7-9H,2,5-6,10-12H2,1H3,(H2,24,26)	RUUFULDNAISCMR-UHFFFAOYSA-N	149835	US8975415, RP116::US9242973, RP116	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149835&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90026778	252159363							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288718	Cc1ncncc1-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:27|	InChI=1S/C21H22N4O3/c1-13-15(8-23-12-24-13)14-3-4-17-16(7-14)21(11-27-18(22)25-21)19(9-26-10-19)20(28-17)5-2-6-20/h3-4,7-8,12H,2,5-6,9-11H2,1H3,(H2,22,25)	ZNEBJRVYFYIQSP-UHFFFAOYSA-N	149836	US8975415, RP117::US9242973, RP117	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149836&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246734	252159364							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288719	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc(c1)C(F)F |t:1|	InChI=1S/C22H21F2N3O3/c23-18(24)15-6-14(8-26-9-15)13-2-3-17-16(7-13)22(12-29-19(25)27-22)20(10-28-11-20)21(30-17)4-1-5-21/h2-3,6-9,18H,1,4-5,10-12H2,(H2,25,27)	HSUAECWUMSPRSF-UHFFFAOYSA-N	149837	US8975415, RP118::US9242973, RP118	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149837&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056204	252159365							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288720	COc1cccc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:26|	InChI=1S/C22H24N2O4/c1-20(2)21(11-26-12-21)22(13-27-19(23)24-22)17-10-15(7-8-18(17)28-20)14-5-4-6-16(9-14)25-3/h4-10H,11-13H2,1-3H3,(H2,23,24)	NTYCQRSCQKAIKY-UHFFFAOYSA-N	149861	US8975415, RP142::US9242973, RP142	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149861	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149861&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246736	252159389							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288721	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cc(Cl)cnc1F |c:15|	InChI=1S/C20H19ClFN3O3/c1-18(2)19(8-26-9-19)20(10-27-17(23)25-20)14-5-11(3-4-15(14)28-18)13-6-12(21)7-24-16(13)22/h3-7H,8-10H2,1-2H3,(H2,23,25)	GETMSLAWJGDJFJ-UHFFFAOYSA-N	149873	US8975415, RP154::US9242973, RP154	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056479	252159401							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288722	NC1=NC2(CO1)c1cc(Br)ccc1OCC21CC(F)(F)C1 |t:1|	InChI=1S/C14H13BrF2N2O2/c15-8-1-2-10-9(3-8)14(7-21-11(18)19-14)12(6-20-10)4-13(16,17)5-12/h1-3H,4-7H2,(H2,18,19)	UWKRYKVCCZEOQP-UHFFFAOYSA-N	149907	US8975415, RP188::US9242973, RP188	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149907	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149907&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056348	252159435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288723	NC1=NC2(CO1)c1cc(NC(=O)c3ncc(Br)cn3)ccc1OCC21CC1 |t:1|	InChI=1S/C18H16BrN5O3/c19-10-6-21-14(22-7-10)15(25)23-11-1-2-13-12(5-11)18(9-27-16(20)24-18)17(3-4-17)8-26-13/h1-2,5-7H,3-4,8-9H2,(H2,20,24)(H,23,25)	RUPHOSKJXJYHAD-UHFFFAOYSA-N	149908	US8975415, RP189::US9242973, RP189	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149908&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056336	252159436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288724	CC1(C)Oc2ccc(NC(=O)c3ncc(Br)cn3)cc2C2(COC(N)=N2)C11COC1 |c:26|	InChI=1S/C20H20BrN5O4/c1-18(2)19(8-28-9-19)20(10-29-17(22)26-20)13-5-12(3-4-14(13)30-18)25-16(27)15-23-6-11(21)7-24-15/h3-7H,8-10H2,1-2H3,(H2,22,26)(H,25,27)	OKNLKKUCXCACGI-UHFFFAOYSA-N	149909	US8975415, RP190::US9242973, 190	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149909	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149909&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025105	252159437							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288725	Cc1cc(cnc1C(=O)Nc1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1)C#N |c:25|	InChI=1S/C21H19N5O3/c1-12-6-13(8-22)9-24-17(12)18(27)25-14-2-3-16-15(7-14)21(11-29-19(23)26-21)20(4-5-20)10-28-16/h2-3,6-7,9H,4-5,10-11H2,1H3,(H2,23,26)(H,25,27)	LUKKVICWYPMUPG-UHFFFAOYSA-N	149910	US8975415, RP191::US9242973, RP191	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149910	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149910&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90248978	252159438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288726	NC1=NC2(CO1)c1cc(NC(=O)c3ncc(cc3Cl)C#N)ccc1OCC21CC1 |t:1|	InChI=1S/C20H16ClN5O3/c21-14-5-11(7-22)8-24-16(14)17(27)25-12-1-2-15-13(6-12)20(10-29-18(23)26-20)19(3-4-19)9-28-15/h1-2,5-6,8H,3-4,9-10H2,(H2,23,26)(H,25,27)	OBYNGUKQVYJXLG-UHFFFAOYSA-N	149911	US8975415, RP192::US9242973, RP192	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149911	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149911&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90248994	252159439							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288727	COc1cnc(cn1)C(=O)Nc1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:26|	InChI=1S/C19H19N5O4/c1-26-15-8-21-13(7-22-15)16(25)23-11-2-3-14-12(6-11)19(10-28-17(20)24-19)18(4-5-18)9-27-14/h2-3,6-8H,4-5,9-10H2,1H3,(H2,20,24)(H,23,25)	IPNOFVHQRLOFQU-UHFFFAOYSA-N	149912	US8975415, RP193::US9242973, RP193	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149912	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149912&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056104	252159440							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288728	Cc1cc(Cl)cnc1C(=O)Nc1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:26|	InChI=1S/C20H19ClN4O3/c1-11-6-12(21)8-23-16(11)17(26)24-13-2-3-15-14(7-13)20(10-28-18(22)25-20)19(4-5-19)9-27-15/h2-3,6-8H,4-5,9-10H2,1H3,(H2,22,25)(H,24,26)	UGPKGDXAPPRVIR-UHFFFAOYSA-N	149913	US8975415, RP194::US9242973, RP194	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4910						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149913	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149913&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056343	252159441							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288729	Cc1cc(Cl)cnc1C(=O)Nc1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:29|	InChI=1S/C22H23ClN4O4/c1-12-6-13(23)8-25-17(12)18(28)26-14-4-5-16-15(7-14)22(11-30-19(24)27-22)21(9-29-10-21)20(2,3)31-16/h4-8H,9-11H2,1-3H3,(H2,24,27)(H,26,28)	WTTPTTMLIGTSRC-UHFFFAOYSA-N	149914	US8975415, RP195::US9242973, 195	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149914	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149914&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548944	252159442							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288730	NC1=NC2(CO1)c1cc(NC(=O)c3ccc(cn3)C#N)ccc1OCC21CC1 |t:1|	InChI=1S/C20H17N5O3/c21-8-12-1-3-15(23-9-12)17(26)24-13-2-4-16-14(7-13)20(11-28-18(22)25-20)19(5-6-19)10-27-16/h1-4,7,9H,5-6,10-11H2,(H2,22,25)(H,24,26)	FCSDLAQZROWWFP-UHFFFAOYSA-N	149915	US8975415, RP196::US9242973, RP196	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3650						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149915&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90248997	252159443							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288731	CC1(C)Oc2ccc(NC(=O)c3ccc(cn3)C#N)cc2C2(COC(N)=N2)C11COC1 |c:27|	InChI=1S/C22H21N5O4/c1-20(2)21(10-29-11-21)22(12-30-19(24)27-22)15-7-14(4-6-17(15)31-20)26-18(28)16-5-3-13(8-23)9-25-16/h3-7,9H,10-12H2,1-2H3,(H2,24,27)(H,26,28)	GPWZMCGYHYETLO-UHFFFAOYSA-N	149916	US8975415, RP197::US9242973, 197	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149916	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149916&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548945	252159444							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288732	NC1=NC2(c3cc(ccc3OCC22CC2)-c2cncnc2)C(F)(F)CS1 |t:1|	InChI=1S/C18H16F2N4OS/c19-17(20)9-26-15(21)24-18(17)13-5-11(12-6-22-10-23-7-12)1-2-14(13)25-8-16(18)3-4-16/h1-2,5-7,10H,3-4,8-9H2,(H2,21,24)	UMLIDFYGFDMIGZ-UHFFFAOYSA-N	149917	US8975415, RP198::US9242973, RP198	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149917	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149917&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724315	252159445							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288733	NC1=NC2(c3cccc(F)c13)c1cc(ccc1OCC21CC1)-c1cncnc1 |t:1|	InChI=1S/C22H17FN4O/c23-17-3-1-2-15-19(17)20(24)27-22(15)16-8-13(14-9-25-12-26-10-14)4-5-18(16)28-11-21(22)6-7-21/h1-5,8-10,12H,6-7,11H2,(H2,24,27)	LEFCQXUNQUOKDG-UHFFFAOYSA-N	149918	US8975415, RP199::US9242973, RP199	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4250						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149918	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149918&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056126	252159446							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288734	NC1=NC2(CO1)c1cc(ccc1OC(Cc1ccccc1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C24H22N4O3/c25-22-28-24(14-30-22)19-9-17(18-10-26-15-27-11-18)6-7-20(19)31-21(23(24)12-29-13-23)8-16-4-2-1-3-5-16/h1-7,9-11,15,21H,8,12-14H2,(H2,25,28)	STMXAUVFLJMWDN-UHFFFAOYSA-N	149919	US8975415, RP202::US8975415, RP200::US9242973, RP202	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246750	252159447							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288735	NC1=NC2(CO1)c1cc(ccc1OC(Cc1ccccc1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C24H22N4O3/c25-22-28-24(14-30-22)19-9-17(18-10-26-15-27-11-18)6-7-20(19)31-21(23(24)12-29-13-23)8-16-4-2-1-3-5-16/h1-7,9-11,15,21H,8,12-14H2,(H2,25,28)	STMXAUVFLJMWDN-UHFFFAOYSA-N	149919	US8975415, RP202::US8975415, RP200::US9242973, RP202	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7730						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246750	252159447							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288736	NC1=NC2(CO1)c1cc(ccc1OC(CC1CC1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C21H22N4O3/c22-19-25-21(11-27-19)16-6-14(15-7-23-12-24-8-15)3-4-17(16)28-18(5-13-1-2-13)20(21)9-26-10-20/h3-4,6-8,12-13,18H,1-2,5,9-11H2,(H2,22,25)	MSVXPEWIJQOLDG-UHFFFAOYSA-N	149923	US8975415, RP207::US8975415, RP204::US9242973, RP207	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149923	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149923&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246751	252159449							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288737	CC#Cc1cncc(c1)-c1ccc2OC(CC3CC3)C3(COC3)C3(COC(N)=N3)c2c1 |c:30|	InChI=1S/C25H25N3O3/c1-2-3-17-8-19(12-27-11-17)18-6-7-21-20(10-18)25(15-30-23(26)28-25)24(13-29-14-24)22(31-21)9-16-4-5-16/h6-8,10-12,16,22H,4-5,9,13-15H2,1H3,(H2,26,28)	KJZOKUPYIWIFKS-UHFFFAOYSA-N	149924	US8975415, RP205::US9242973, RP205	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5220						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149924	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149924&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056128	252159450							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288738	NC1=NC2(c3cc(ccc3OCC22CC2)-c2cncnc2)C(F)(F)CO1 |t:1|	InChI=1S/C18H16F2N4O2/c19-17(20)9-26-15(21)24-18(17)13-5-11(12-6-22-10-23-7-12)1-2-14(13)25-8-16(18)3-4-16/h1-2,5-7,10H,3-4,8-9H2,(H2,21,24)	QZZCXMLMCPDROH-UHFFFAOYSA-N	149925	US8975415, RP206::US9242973, RP206	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149925	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149925&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056130	252159451							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288739	NC1=NC2(CO1)c1cc(ccc1OC(CC1CC1)C21COC1)-c1cncnc1 |t:1|	InChI=1S/C21H22N4O3/c22-19-25-21(11-27-19)16-6-14(15-7-23-12-24-8-15)3-4-17(16)28-18(5-13-1-2-13)20(21)9-26-10-20/h3-4,6-8,12-13,18H,1-2,5,9-11H2,(H2,22,25)	MSVXPEWIJQOLDG-UHFFFAOYSA-N	149923	US8975415, RP207::US8975415, RP204::US9242973, RP207	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149923	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149923&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246751	252159449							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288740	NC1=NC2(CO1)c1cc(ccc1OCC21CC(F)(F)C1)-c1cncnc1 |t:1|	InChI=1S/C18H16F2N4O2/c19-17(20)6-16(7-17)8-25-14-2-1-11(12-4-22-10-23-5-12)3-13(14)18(16)9-26-15(21)24-18/h1-5,10H,6-9H2,(H2,21,24)	IBQLKXDWVJSRDU-UHFFFAOYSA-N	149927	US8975415, RP208::US9242973, RP208	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149927	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149927&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056127	252159452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288741	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1 |t:1|	InChI=1S/C21H21N3O3/c22-18-24-21(13-26-18)16-9-14(15-3-1-8-23-10-15)4-5-17(16)27-20(6-2-7-20)19(21)11-25-12-19/h1,3-5,8-10H,2,6-7,11-13H2,(H2,22,24)	MJGALTWQDCBMQD-UHFFFAOYSA-N	149928	US8975415, RP209::US9242973, RP209	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149928	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056129	252159453							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288742	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc2ccccc12 |t:1|	InChI=1S/C25H23N3O3/c26-22-28-25(15-30-22)20-10-16(19-12-27-11-17-4-1-2-5-18(17)19)6-7-21(20)31-24(8-3-9-24)23(25)13-29-14-23/h1-2,4-7,10-12H,3,8-9,13-15H2,(H2,26,28)	NFVBGAGTKRCWGE-UHFFFAOYSA-N	149929	US8975415, RP210::US9242973, RP210	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3700						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149929	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149929&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246752	252159454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288743	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1C(F)(F)F |t:1|	InChI=1S/C22H20F3N3O3/c23-22(24,25)17-14(3-1-8-27-17)13-4-5-16-15(9-13)21(12-30-18(26)28-21)19(10-29-11-19)20(31-16)6-2-7-20/h1,3-5,8-9H,2,6-7,10-12H2,(H2,26,28)	XPOQBFAIFSUYIN-UHFFFAOYSA-N	149931	US8975415, RP212::US9242973, RP212	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149931	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149931&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056510	252159456							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288744	Cn1cc2cc(ccc2n1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1 |c:26|	InChI=1S/C21H20N4O2/c1-25-10-15-8-13(2-4-17(15)24-25)14-3-5-18-16(9-14)21(12-27-19(22)23-21)20(6-7-20)11-26-18/h2-5,8-10H,6-7,11-12H2,1H3,(H2,22,23)	LYIYOHNNHUSMFQ-UHFFFAOYSA-N	149932	US8975415, RP213::US9242973, RP213	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149932	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149932&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056496	252159457							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288745	NC1=NC2(COC1)c1cc(ccc1OCC21CC1)-c1cncnc1 |t:1|	InChI=1S/C18H18N4O2/c19-16-8-23-10-18(22-16)14-5-12(13-6-20-11-21-7-13)1-2-15(14)24-9-17(18)3-4-17/h1-2,5-7,11H,3-4,8-10H2,(H2,19,22)	AMQPJZMLPSZGED-UHFFFAOYSA-N	149934	US8975415, RP215::US9242973, RP215	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149934	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149934&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025994	252159459							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288746	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@@]2(COC(N)=N2)C11COC1 |r,c:26|	InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	INWIVMOTHPFWNU-UHFFFAOYSA-N	149936	US8975415, 218::US9242973, 218	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20670						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149936	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149936&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72202470	252159461							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288747	CC1(C)Oc2ccc(NC(=O)c3ccc(Br)cn3)cc2[C@@]2(COC(N)=N2)C11COC1 |r,c:26|	InChI=1S/C21H21BrN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	CWCLNAMDVBTHAU-UHFFFAOYSA-N	149937	US8975415, 219::US9242973, 219	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149937&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90236720	252159462							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288748	COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(COC3)[C@]3(COC(N)=N3)c2c1 |r,c:29|	InChI=1S/C21H23N5O5/c1-19(2)20(9-29-10-20)21(11-30-18(22)26-21)13-6-12(4-5-15(13)31-19)25-17(27)14-7-24-16(28-3)8-23-14/h4-8H,9-11H2,1-3H3,(H2,22,26)(H,25,27)	WZWNQLAVZZUSHH-UHFFFAOYSA-N	149938	US8975415, 220::US9242973, 220	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149938	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149938&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548948	252159463							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288749	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@@]2(COC(N)=N2)C11CC1 |r,c:26|	InChI=1S/C21H21ClN4O3/c1-19(2)20(7-8-20)21(11-28-18(23)26-21)14-9-13(4-6-16(14)29-19)25-17(27)15-5-3-12(22)10-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,23,26)(H,25,27)	SUARPGUFOBBSJS-UHFFFAOYSA-N	149939	US8975415, 221::US9242973, 221	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3250						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056502	252159464							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288750	CC1(C)Oc2ccc(NC(=O)c3ccc(F)cn3)cc2[C@@]2(COC(N)=N2)C11CC1 |r,c:26|	InChI=1S/C21H21FN4O3/c1-19(2)20(7-8-20)21(11-28-18(23)26-21)14-9-13(4-6-16(14)29-19)25-17(27)15-5-3-12(22)10-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,23,26)(H,25,27)	KFVQLLMGMYDUOM-UHFFFAOYSA-N	149940	US8975415, 222::US9242973, 222	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149940	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149940&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056497	252159465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288751	COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(CC3)[C@]3(COC(N)=N3)c2c1 |r,c:28|	InChI=1S/C21H23N5O4/c1-19(2)20(6-7-20)21(11-29-18(22)26-21)13-8-12(4-5-15(13)30-19)25-17(27)14-9-24-16(28-3)10-23-14/h4-5,8-10H,6-7,11H2,1-3H3,(H2,22,26)(H,25,27)	FVLGCKAZTKQUNT-UHFFFAOYSA-N	149941	US8975415, 223::US9242973, 223	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20770						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724317	252159466							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288752	CC1(C)Oc2ccc(NC(=O)c3cnc(cn3)C(F)F)cc2[C@@]2(COC(N)=N2)C11CC1 |r,c:28|	InChI=1S/C21H21F2N5O3/c1-19(2)20(5-6-20)21(10-30-18(24)28-21)12-7-11(3-4-15(12)31-19)27-17(29)14-9-25-13(8-26-14)16(22)23/h3-4,7-9,16H,5-6,10H2,1-2H3,(H2,24,28)(H,27,29)	UUOAKQJQRFDOFS-UHFFFAOYSA-N	149942	US8975415, 224::US9242973, 224	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15100						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149942	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149942&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724318	252159467							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288753	COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1 |c:29|	InChI=1S/C21H23N5O5/c1-19(2)20(9-29-10-20)21(11-30-18(22)26-21)13-6-12(4-5-15(13)31-19)25-17(27)14-7-24-16(28-3)8-23-14/h4-8H,9-11H2,1-3H3,(H2,22,26)(H,25,27)	WZWNQLAVZZUSHH-UHFFFAOYSA-N	149943	US8975415, 227::US9242973, 227	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149943	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149943&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724320	252159468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
288754	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@]2(COC(N)=N2)C11COC1 |r,c:26|	InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	INWIVMOTHPFWNU-UHFFFAOYSA-N	149944	US8975415, 228a::US9242973, 228a	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2SB44GN		aid1800972	US8975415	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shina, Y; Samizu, K; Hamaguchi, H; Hong, L	3/10/2015	8/10/2015	Comentis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149944	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149944&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548947	252159469							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312417	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccccc1 |r|	InChI=1S/C23H29N3O3/c1-3-19(17-9-5-4-6-10-17)24-22(27)18-14-20(26-12-13-29-15-21(18)26)23(28)25-11-7-8-16(25)2/h4-6,9-10,14,16,19H,3,7-8,11-13,15H2,1-2H3,(H,24,27)	LLAVWQQOTBFOFF-UHFFFAOYSA-N	218251	US9284333, 16a::US9884860, Example 16a	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218251	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218251&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696125	329969717							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312418	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1cnc(OC)c(Cl)c1 |r|	InChI=1S/C23H29ClN4O4/c1-4-18(15-10-17(24)22(31-3)25-12-15)26-21(29)16-11-19(28-8-9-32-13-20(16)28)23(30)27-7-5-6-14(27)2/h10-12,14,18H,4-9,13H2,1-3H3,(H,26,29)	UBUZPRWNQWEPLH-UHFFFAOYSA-N	218252	US9284333, 16b::US9884860, Example 16b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218252	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218252&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696260	329969718							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312419	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccc(c(Cl)c1)C(F)(F)F |r|	InChI=1S/C24H27ClF3N3O3/c1-3-19(15-6-7-17(18(25)11-15)24(26,27)28)29-22(32)16-12-20(31-9-10-34-13-21(16)31)23(33)30-8-4-5-14(30)2/h6-7,11-12,14,19H,3-5,8-10,13H2,1-2H3,(H,29,32)	JCBZELCVZUFNOM-UHFFFAOYSA-N	218253	US9284333, 16c	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218253	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218253&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696325	329969719							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312420	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C23H27Cl2N3O3/c1-3-19(15-6-7-17(24)18(25)11-15)26-22(29)16-12-20(28-9-10-31-13-21(16)28)23(30)27-8-4-5-14(27)2/h6-7,11-12,14,19H,3-5,8-10,13H2,1-2H3,(H,26,29)	DWMYZHDZTBDFJZ-UHFFFAOYSA-N	218343	US9284333, 16ci::US9884860, Example 16ci	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218343	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218343&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696327	329969794							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312421	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccc(C#N)c(Cl)c1 |r|	InChI=1S/C24H27ClN4O3/c1-3-20(16-6-7-17(13-26)19(25)11-16)27-23(30)18-12-21(29-9-10-32-14-22(18)29)24(31)28-8-4-5-15(28)2/h6-7,11-12,15,20H,3-5,8-10,14H2,1-2H3,(H,27,30)	HHOVMBFTSSHMBV-UHFFFAOYSA-N	218254	US9284333, 16d::US9884860, Example 16d	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218254	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218254&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696258	329969720							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312422	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccc(nc1)C(F)(F)F |r|	InChI=1S/C23H27F3N4O3/c1-3-17(15-6-7-20(27-12-15)23(24,25)26)28-21(31)16-11-18(30-9-10-33-13-19(16)30)22(32)29-8-4-5-14(29)2/h6-7,11-12,14,17H,3-5,8-10,13H2,1-2H3,(H,28,31)	OEGNOLHLTZVBSU-UHFFFAOYSA-N	218255	US9284333, 16e::US9884860, Example 16e	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218255	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218255&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696128	329969721							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312423	CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2CCOCc12)c1ccc(cc1)C(F)(F)F |r|	InChI=1S/C27H27F4N3O3/c1-3-22(18-4-8-19(9-5-18)27(29,30)31)33-25(35)21-14-23(34-12-13-37-15-24(21)34)26(36)32-16(2)17-6-10-20(28)11-7-17/h4-11,14,16,22H,3,12-13,15H2,1-2H3,(H,32,36)(H,33,35)	IZIHXOVBTCYLJE-UHFFFAOYSA-N	218383	US9284333, 16eb::US9884860, Example 16eb	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218383&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71695937	329969829							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312424	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccc(cc1)C(F)(F)F |r|	InChI=1S/C24H28F3N3O3/c1-3-19(16-6-8-17(9-7-16)24(25,26)27)28-22(31)18-13-20(30-11-12-33-14-21(18)30)23(32)29-10-4-5-15(29)2/h6-9,13,15,19H,3-5,10-12,14H2,1-2H3,(H,28,31)	DAFYDSHNCYDLLI-UHFFFAOYSA-N	218256	US9284333, 16f::US9884860, Example 16f	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218256	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218256&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696194	329969722							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312425	CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2CCOCc12)c1ccc(nc1)C(F)(F)F |r|	InChI=1S/C26H26F4N4O3/c1-3-20(17-6-9-23(31-13-17)26(28,29)30)33-24(35)19-12-21(34-10-11-37-14-22(19)34)25(36)32-15(2)16-4-7-18(27)8-5-16/h4-9,12-13,15,20H,3,10-11,14H2,1-2H3,(H,32,36)(H,33,35)	OHCNJPKWXUAUCG-UHFFFAOYSA-N	218257	US9284333, 16g::US9884860, Example 16g	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218257	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218257&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71695938	329969723							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312426	CC[C@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2CCOCc12)c1ncccn1 |r|	InChI=1S/C24H26FN5O3/c1-3-19(22-26-9-4-10-27-22)29-23(31)18-13-20(30-11-12-33-14-21(18)30)24(32)28-15(2)16-5-7-17(25)8-6-16/h4-10,13,15,19H,3,11-12,14H2,1-2H3,(H,28,32)(H,29,31)	WMOWXUZSPFIQOB-UHFFFAOYSA-N	218258	US9284333, 16h::US9884860, Example 16h	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218258	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218258&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696002	329969724							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312427	CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2CCOCc12)c1ccccc1 |r|	InChI=1S/C27H31N3O3/c1-3-22(19-11-7-5-8-12-19)28-26(31)21-17-24(30-15-16-33-18-25(21)30)27(32)29-23(4-2)20-13-9-6-10-14-20/h5-14,17,22-23H,3-4,15-16,18H2,1-2H3,(H,28,31)(H,29,32)	OIAHOHDKGALLJK-UHFFFAOYSA-N	218259	BDBM218669::US9284333, 16i::US9884860, Example 16ry	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218259	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218259&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71660508	329969725							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312428	CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccc(OC)nc2)n2CCOCc12)c1ccccc1 |r|	InChI=1S/C27H32N4O4/c1-4-21(18-9-7-6-8-10-18)29-26(32)20-15-23(31-13-14-35-17-24(20)31)27(33)30-22(5-2)19-11-12-25(34-3)28-16-19/h6-12,15-16,21-22H,4-5,13-14,17H2,1-3H3,(H,29,32)(H,30,33)	HKEPMSLDUUTCJS-UHFFFAOYSA-N	218260	US9284333, 16j::US9884860, Example 16j	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218260	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218260&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71695685	329969726							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312429	CCOC(=O)CNC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2COCCn12 |r|	InChI=1S/C22H27N3O5/c1-3-17(15-8-6-5-7-9-15)24-21(27)16-12-18(25-10-11-29-14-19(16)25)22(28)23-13-20(26)30-4-2/h5-9,12,17H,3-4,10-11,13-14H2,1-2H3,(H,23,28)(H,24,27)	GTSTWVBFSMJCJH-UHFFFAOYSA-N	218261	US9284333, 16k::US9884860, Example 16k	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218261	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218261&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71695619	329969727							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312430	CCOC(=O)[C@H](C)N(C)C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2COCCn12 |r|	InChI=1S/C24H31N3O5/c1-5-19(17-10-8-7-9-11-17)25-22(28)18-14-20(27-12-13-31-15-21(18)27)23(29)26(4)16(3)24(30)32-6-2/h7-11,14,16,19H,5-6,12-13,15H2,1-4H3,(H,25,28)	MCOHRYNEZCKQCX-UHFFFAOYSA-N	218262	US9284333, 16l::US9884860, Example 16l	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218262	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218262&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696589	329969728							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312431	Fc1ccc(cc1)[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)n2CCOCc12)C1CC1 |r|	InChI=1S/C23H26FN3O3/c24-17-7-5-16(6-8-17)21(15-3-4-15)25-22(28)18-13-19(23(29)26-9-1-2-10-26)27-11-12-30-14-20(18)27/h5-8,13,15,21H,1-4,9-12,14H2,(H,25,28)	ILQBHKSACDWKNL-UHFFFAOYSA-N	218364	US9284333, 16dh::US9884860, Example 16dh	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218364	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218364&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			89734006	329969813							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312432	CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(F)(F)F)n2CCOCc12)c1ccc(nc1)C(F)(F)F |r|	InChI=1S/C23H24F6N4O3/c1-2-15(13-5-6-18(30-11-13)22(24,25)26)31-20(34)14-10-16(32-8-9-36-12-17(14)32)21(35)33-7-3-4-19(33)23(27,28)29/h5-6,10-11,15,19H,2-4,7-9,12H2,1H3,(H,31,34)	OOTYVFPUEZJGJY-UHFFFAOYSA-N	218266	US9284333, 16o::US9884860, Example 16o	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000						25.00 C	US Patent		10.7270/Q2FJ2FMC		aid1802495	US9284333	Bialy, L; Lorenz, K; Wirth, K; Steinmeyer, K; Hessler, G	3/15/2016	3/21/2017	Sanofi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218266	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218266&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71696257	329969732							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312465	[H][C@@]12CCOC[C@@]1(N=C(N)SC2)c1cc(NC(=O)c2ccc(OC(F)F)cn2)ccc1F |t:8|	InChI=1S/C20H19F3N4O3S/c21-15-3-1-12(26-17(28)16-4-2-13(8-25-16)30-18(22)23)7-14(15)20-10-29-6-5-11(20)9-31-19(24)27-20/h1-4,7-8,11,18H,5-6,9-10H2,(H2,24,27)(H,26,28)	QRAMMCLVMBTOID-UHFFFAOYSA-N	223406	US9315520, Comparator 4::US9605007, Comparator 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 500						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223406&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			45279898	336285274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312466	[H][C@]12CSC(N)=N[C@]1(CO[C@@H](C)C2)c1cc(NC(=O)c2ccc(cn2)C#N)cs1 |c:5|	InChI=1S/C19H19N5O2S2/c1-11-4-13-8-28-18(21)24-19(13,10-26-11)16-5-14(9-27-16)23-17(25)15-3-2-12(6-20)7-22-15/h2-3,5,7,9,11,13H,4,8,10H2,1H3,(H2,21,24)(H,23,25)	YIXDWYJNAHJADD-UHFFFAOYSA-N	223408	US9315520, Comparator 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1800						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223408	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223408&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118446134	336285276							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312469	[H][C@]12CSC(N)=N[C@]1(CO[C@@H](C)C2)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F |c:5|	InChI=1S/C20H20ClFN4O2S/c1-11-6-12-9-29-19(23)26-20(12,10-28-11)15-7-14(3-4-16(15)22)25-18(27)17-5-2-13(21)8-24-17/h2-5,7-8,11-12H,6,9-10H2,1H3,(H2,23,26)(H,25,27)	UOHXUSCZQJMWQO-UHFFFAOYSA-N	223358	US9315520, Comparator 7::US9605007, Comparator 7::US9744173, Comparator 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 200						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223358&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			45279589	336285233							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312541	O[C@H](COc1ccc(O)cc1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C19H23ClN2O3/c20-15-1-3-16(4-2-15)22-11-9-21(10-12-22)13-18(24)14-25-19-7-5-17(23)6-8-19/h1-8,18,23-24H,9-14H2	BQYPFLYRFTYVGP-UHFFFAOYSA-N	168616	US9079852, Table F, Compound 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 39000								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			57907982	312525547							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312542	O[C@H](COc1ccc2[nH]c(=O)oc2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C20H22ClN3O4/c21-14-1-3-15(4-2-14)24-9-7-23(8-10-24)12-16(25)13-27-17-5-6-18-19(11-17)28-20(26)22-18/h1-6,11,16,25H,7-10,12-13H2,(H,22,26)	LHWHFMYAQCTHNB-UHFFFAOYSA-N	168617	US9079852, Table F, Compound 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1600								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168617&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			25160230	312525548							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312543	CS(=O)(=O)Nc1ccc(OC[C@@H](O)CN2CCN(CC2)c2ccc(Cl)cc2)cc1 |r|	InChI=1S/C20H26ClN3O4S/c1-29(26,27)22-17-4-8-20(9-5-17)28-15-19(25)14-23-10-12-24(13-11-23)18-6-2-16(21)3-7-18/h2-9,19,22,25H,10-15H2,1H3	VDICSHQGASSQTF-UHFFFAOYSA-N	168618	US9079852, Table F, Compound 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 553								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			25160361	312525549							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312544	NC(=O)Nc1ccc(OC[C@@H](O)CN2CCN(CC2)c2ccc(Cl)cc2)cc1 |r|	InChI=1S/C20H25ClN4O3/c21-15-1-5-17(6-2-15)25-11-9-24(10-12-25)13-18(26)14-28-19-7-3-16(4-8-19)23-20(22)27/h1-8,18,26H,9-14H2,(H3,22,23,27)	GSOWCEUNQPJIFR-UHFFFAOYSA-N	168619	US9079852, Table F, Compound 4::US20240360091, Compound (10075)S	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 13000								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168619	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168619&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			25113672	312525550							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312545	O[C@H](COc1ccc2[nH]ncc2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C20H23ClN4O2/c21-16-1-3-17(4-2-16)25-9-7-24(8-10-25)13-18(26)14-27-19-5-6-20-15(11-19)12-22-23-20/h1-6,11-12,18,26H,7-10,13-14H2,(H,22,23)	NKOFOWFCZADIGL-UHFFFAOYSA-N	168620	US9079852, Table F, Compound 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1000								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168620&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			57908035	312525551							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312546	O[C@H](COc1ccc2[nH]c(=O)ccc2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C22H24ClN3O3/c23-17-2-4-18(5-3-17)26-11-9-25(10-12-26)14-19(27)15-29-20-6-7-21-16(13-20)1-8-22(28)24-21/h1-8,13,19,27H,9-12,14-15H2,(H,24,28)	MOVHEMVZXCWLLK-UHFFFAOYSA-N	168621	US9079852, Table F, Compound 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7500								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168621	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168621&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118796640	312525552							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312547	O[C@H](COc1ccc2[nH]c(=O)[nH]c2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C20H23ClN4O3/c21-14-1-3-15(4-2-14)25-9-7-24(8-10-25)12-16(26)13-28-17-5-6-18-19(11-17)23-20(27)22-18/h1-6,11,16,26H,7-10,12-13H2,(H2,22,23,27)	KGUIIIHLRXPBSO-UHFFFAOYSA-N	168622	US9079852, Table F, Compound 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7500								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168622&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118796641	312525553							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312548	O[C@H](COc1ccc2NC(=O)Cc2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C21H24ClN3O3/c22-16-1-3-17(4-2-16)25-9-7-24(8-10-25)13-18(26)14-28-19-5-6-20-15(11-19)12-21(27)23-20/h1-6,11,18,26H,7-10,12-14H2,(H,23,27)	RUXMKHKIUOUGFV-UHFFFAOYSA-N	168624	US9079852, Table F, Compound 9::US20240360091, Compound (10146)S	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 10000								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168624&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			57907725	312525554							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312549	O[C@H](COc1ccc2[nH]c(=S)[nH]c2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C20H23ClN4O2S/c21-14-1-3-15(4-2-14)25-9-7-24(8-10-25)12-16(26)13-27-17-5-6-18-19(11-17)23-20(28)22-18/h1-6,11,16,26H,7-10,12-13H2,(H2,22,23,28)	HPOFGYFNLFMWQD-UHFFFAOYSA-N	168625	US9079852, Table F, Compound 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 7500								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168625	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168625&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118796642	312525555							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
312550	O[C@H](COc1ccc2NC(=O)CCc2c1)CN1CCN(CC1)c1ccc(Cl)cc1 |r|	InChI=1S/C22H26ClN3O3/c23-17-2-4-18(5-3-17)26-11-9-25(10-12-26)14-19(27)15-29-20-6-7-21-16(13-20)1-8-22(28)24-21/h2-7,13,19,27H,1,8-12,14-15H2,(H,24,28)	FFJJKTNCSJWBOG-UHFFFAOYSA-N	168626	US9079852, Table F, Compound 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 5000								US Patent		10.7270/Q2K35SF5		aid1801420	US9079852	Liotta, DC; Snyder, JP; Traynelis, SF; Wilson, L; Mosley, C; Dingledine, RJ; Myers, S; Tahirovic, YA	7/14/2015	3/7/2016	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			57907684	312525556							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315529	CNC(=O)COc1cc2cc(Nc3nc(N4CCC(CN5CCC(C6CCN(c7cccc8c(C9CCC(=O)NC9=O)nn(C)c78)CC6)CC5)CC4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C46H56ClN11O5/c1-48-40(60)27-63-38-24-31-23-32(7-9-36(31)54(2)45(38)62)50-43-35(47)25-49-46(52-43)58-19-11-28(12-20-58)26-56-17-13-29(14-18-56)30-15-21-57(22-16-30)37-6-4-5-33-41(53-55(3)42(33)37)34-8-10-39(59)51-44(34)61/h4-7,9,23-25,28-30,34H,8,10-22,26-27H2,1-3H3,(H,48,60)(H,49,50,52)(H,51,59,61)	JNAXAIXLGOFPLL-UHFFFAOYSA-N	783784	US20250333410, Compound 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783784	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783784&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895806	523302129							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315530	CNC(=O)COc1cc2cc(Nc3nc(N4CCC(CN5CCC(c6cccc7c6n(C)c(=O)n7C6CCC(=O)NC6=O)CC5)CC4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C41H47ClN10O6/c1-43-35(54)23-58-33-20-26-19-27(7-8-30(26)48(2)39(33)56)45-37-29(42)21-44-40(47-37)51-17-11-24(12-18-51)22-50-15-13-25(14-16-50)28-5-4-6-31-36(28)49(3)41(57)52(31)32-9-10-34(53)46-38(32)55/h4-8,19-21,24-25,32H,9-18,22-23H2,1-3H3,(H,43,54)(H,44,45,47)(H,46,53,55)	AJFGRUDOBCOGFX-UHFFFAOYSA-N	783785	US20250333410, Compound 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895807	523302130							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315531	CNC(=O)COc1cc2cc(Nc3nc(N4CCN(CC5CCN(c6ccc7c8c(oc7c6)C(=O)N(C6CCC(=O)NC6=O)C8)CC5)CC4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C42H45ClN10O7/c1-44-36(55)23-59-34-18-25-17-26(3-6-31(25)49(2)40(34)57)46-38-30(43)20-45-42(48-38)52-15-13-50(14-16-52)21-24-9-11-51(12-10-24)27-4-5-28-29-22-53(32-7-8-35(54)47-39(32)56)41(58)37(29)60-33(28)19-27/h3-6,17-20,24,32H,7-16,21-23H2,1-2H3,(H,44,55)(H,45,46,48)(H,47,54,56)	GMXHMQMYAPKEPQ-UHFFFAOYSA-N	783786	US20250333410, Compound 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895808	523302131							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315532	CNC(=O)COc1cc2cc(Nc3nc(N4CCN(CC5CC6(CCN(c7scc8c7C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)C5)CC4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C41H45ClN10O7S/c1-43-32(54)21-59-30-16-24-15-25(3-4-28(24)48(2)37(30)57)45-34-27(42)19-44-40(47-34)51-13-11-49(12-14-51)20-23-17-41(18-23)7-9-50(10-8-41)39-33-26(22-60-39)36(56)52(38(33)58)29-5-6-31(53)46-35(29)55/h3-4,15-16,19,22-23,29H,5-14,17-18,20-21H2,1-2H3,(H,43,54)(H,44,45,47)(H,46,53,55)	AKGNPSBWWLMKBW-UHFFFAOYSA-N	783787	US20250333410, Compound 67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783787	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783787&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895809	523302132							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315533	CNC(=O)COc1cc2cc(Nc3nc(N4CCC(N5CCN(c6ccc(NC7CCC(=O)NC7=O)cc6F)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C37H40ClF3N10O5/c1-42-32(53)19-56-29-16-21-15-22(3-6-27(21)48(2)35(29)55)45-33-24(38)18-43-36(47-33)51-10-9-30(37(40,41)20-51)50-13-11-49(12-14-50)28-7-4-23(17-25(28)39)44-26-5-8-31(52)46-34(26)54/h3-4,6-7,15-18,26,30,44H,5,8-14,19-20H2,1-2H3,(H,42,53)(H,43,45,47)(H,46,52,54)	HNGBVKHGWAEVAB-UHFFFAOYSA-N	783788	US20250333410, Compound 71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783788	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783788&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895810	523302133							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315534	CNC(=O)COc1cc2cc(Nc3nc(N4CC[C@@H](N5CCN(c6ccc(N[C@@H]7CCC(=O)NC7=O)cc6F)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C37H40ClF3N10O5/c1-42-32(53)19-56-29-16-21-15-22(3-6-27(21)48(2)35(29)55)45-33-24(38)18-43-36(47-33)51-10-9-30(37(40,41)20-51)50-13-11-49(12-14-50)28-7-4-23(17-25(28)39)44-26-5-8-31(52)46-34(26)54/h3-4,6-7,15-18,26,30,44H,5,8-14,19-20H2,1-2H3,(H,42,53)(H,43,45,47)(H,46,52,54)	HNGBVKHGWAEVAB-UHFFFAOYSA-N	783789	US20250333410, Compound 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895811	523302134							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315535	CNC(=O)COc1cc2cc(Nc3nc(N4CC[C@H](N5CCN(c6ccc(N[C@@H]7CCC(=O)NC7=O)cc6F)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C37H40ClF3N10O5/c1-42-32(53)19-56-29-16-21-15-22(3-6-27(21)48(2)35(29)55)45-33-24(38)18-43-36(47-33)51-10-9-30(37(40,41)20-51)50-13-11-49(12-14-50)28-7-4-23(17-25(28)39)44-26-5-8-31(52)46-34(26)54/h3-4,6-7,15-18,26,30,44H,5,8-14,19-20H2,1-2H3,(H,42,53)(H,43,45,47)(H,46,52,54)	HNGBVKHGWAEVAB-UHFFFAOYSA-N	783790	US20250333410, Compound 73	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783790	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783790&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895812	523302135							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315536	CC(=O)COc1cc2cc(Nc3nc(N4CC[C@@H](N5CCN(c6ccc(N[C@H]7CCC(=O)NC7=O)cc6F)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C37H39ClF3N9O5/c1-21(51)19-55-30-16-22-15-23(3-6-28(22)47(2)35(30)54)44-33-25(38)18-42-36(46-33)50-10-9-31(37(40,41)20-50)49-13-11-48(12-14-49)29-7-4-24(17-26(29)39)43-27-5-8-32(52)45-34(27)53/h3-4,6-7,15-18,27,31,43H,5,8-14,19-20H2,1-2H3,(H,42,44,46)(H,45,52,53)	WIJQRIPODGWSBC-UHFFFAOYSA-N	783791	US20250333410, Compound 75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783791	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783791&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895813	523302136							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315537	CC(=O)COc1cc2cc(Nc3nc(N4CCC(N5CCN(c6c(F)cc(C7CCC(=O)NC7=O)cc6F)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C37H37ClF4N8O5/c1-20(51)18-55-29-16-22-13-23(3-5-28(22)47(2)35(29)54)44-33-25(38)17-43-36(46-33)50-8-7-30(37(41,42)19-50)48-9-11-49(12-10-48)32-26(39)14-21(15-27(32)40)24-4-6-31(52)45-34(24)53/h3,5,13-17,24,30H,4,6-12,18-19H2,1-2H3,(H,43,44,46)(H,45,52,53)	CIXHRKYQYARDER-UHFFFAOYSA-N	783792	US20250333410, Compound 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783792&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895814	523302137							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315538	CNC(=O)COc1cc2cc(Nc3nc(N4CCC(N5CCN(c6cccc7c6n(C)c(=O)n7C6CCC(=O)NC6=O)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C39H42ClF2N11O6/c1-43-32(55)20-59-29-18-22-17-23(7-8-25(22)48(2)36(29)57)45-34-24(40)19-44-37(47-34)52-12-11-30(39(41,42)21-52)51-15-13-50(14-16-51)26-5-4-6-27-33(26)49(3)38(58)53(27)28-9-10-31(54)46-35(28)56/h4-8,17-19,28,30H,9-16,20-21H2,1-3H3,(H,43,55)(H,44,45,47)(H,46,54,56)	PHYHGGKRHAPXCF-UHFFFAOYSA-N	783793	US20250333410, Compound 77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783793	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783793&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895815	523302138							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
315539	CCC(=O)COc1cc2cc(Nc3nc(N4CCC(N5CCN(c6cccc7c(C8CCC(=O)NC8=O)nn(C)c67)CC5)C(F)(F)C4)ncc3Cl)ccc2n(C)c1=O	InChI=1S/C40H43ClF2N10O5/c1-4-25(54)21-58-31-19-23-18-24(8-10-29(23)49(2)38(31)57)45-36-28(41)20-44-39(47-36)53-13-12-32(40(42,43)22-53)52-16-14-51(15-17-52)30-7-5-6-26-34(48-50(3)35(26)30)27-9-11-33(55)46-37(27)56/h5-8,10,18-20,27,32H,4,9,11-17,21-22H2,1-3H3,(H,44,45,47)(H,46,55,56)	HLLHFTITNDQJQV-UHFFFAOYSA-N	783794	US20250333410, Compound 78	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2N302QS		aid1801440	US20250333410	ZHANG, C; LIAO, Y; LU, Y; LI, Y; ZHAO, J; TANG, P; YU, Y; LI, Y; YAN, P	10/30/2025	2/19/2026	Xizang Haisco Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=783794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=783794&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			177895816	523302139							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
340969	Cc1cccc2CCCN(C(=O)CSc3ccc(cn3)C(F)(F)F)c12	InChI=1S/C18H17F3N2OS/c1-12-4-2-5-13-6-3-9-23(17(12)13)16(24)11-25-15-8-7-14(10-22-15)18(19,20)21/h2,4-5,7-8,10H,3,6,9,11H2,1H3	WNBQQNXMFAQPPC-UHFFFAOYSA-N	190576	US9181219, 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2DV1HPH		aid1801846	US9181219	Moran, MM; Chong, JA; Fanger, C; Ripka, AS; Larsen, GR; Zhen, X; Underwood, DJ; Weigele, M	11/10/2015	8/15/2016	Hydra Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=190576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=190576&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24758652	316922102							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
340970	Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12	InChI=1S/C17H17ClN2OS/c1-12-4-2-5-13-6-3-9-20(17(12)13)16(21)11-22-15-8-7-14(18)10-19-15/h2,4-5,7-8,10H,3,6,9,11H2,1H3	AADFPUIVOUZLOS-UHFFFAOYSA-N	190578	US9181219, 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>5000							US Patent		10.7270/Q2DV1HPH		aid1801846	US9181219	Moran, MM; Chong, JA; Fanger, C; Ripka, AS; Larsen, GR; Zhen, X; Underwood, DJ; Weigele, M	11/10/2015	8/15/2016	Hydra Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=190578	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=190578&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24900572	316922104							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
340971	Cc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12	InChI=1S/C17H17ClN2OS/c1-12-5-2-6-13-7-4-10-20(16(12)13)15(21)11-22-17-14(18)8-3-9-19-17/h2-3,5-6,8-9H,4,7,10-11H2,1H3	OFWFWXOQRODVCI-UHFFFAOYSA-N	190579	US9181219, 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2DV1HPH		aid1801846	US9181219	Moran, MM; Chong, JA; Fanger, C; Ripka, AS; Larsen, GR; Zhen, X; Underwood, DJ; Weigele, M	11/10/2015	8/15/2016	Hydra Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=190579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=190579&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24900571	316922105							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G,1UJL	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361870	COCc1cnn(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H24N4O4/c1-26-10-14-8-23-25(9-14)15-3-4-17-16(7-15)21(13-28-18(22)24-21)19(11-27-12-19)20(29-17)5-2-6-20/h3-4,7-9H,2,5-6,10-13H2,1H3,(H2,22,24)	NRTIHHVWKLDASP-UHFFFAOYSA-N	149718	US8975415, RP4::US9242973, RP4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149718&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90055955	252159262							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361871	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncnc1	InChI=1S/C20H20N4O3/c21-17-24-20(11-26-17)15-6-13(14-7-22-12-23-8-14)2-3-16(15)27-19(4-1-5-19)18(20)9-25-10-18/h2-3,6-8,12H,1,4-5,9-11H2,(H2,21,24)	APMDRJOSPMXZBV-UHFFFAOYSA-N	149719	US8975415, RP5::US9242973, RP5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149719&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246703	252159263							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361872	CC1(C)Oc2ccc(Br)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C15H17BrN2O3/c1-13(2)14(6-19-7-14)15(8-20-12(17)18-15)10-5-9(16)3-4-11(10)21-13/h3-5H,6-8H2,1-2H3,(H2,17,18)	BFCFOLFRUMYREH-UHFFFAOYSA-N	149720	US8975415, RP6::US9242973, RP6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149720&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724229	252159264							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361873	CCC1Oc2ccc(Br)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C15H17BrN2O3/c1-2-12-14(6-19-7-14)15(8-20-13(17)18-15)10-5-9(16)3-4-11(10)21-12/h3-5,12H,2,6-8H2,1H3,(H2,17,18)	UVKPJIHODHUWCZ-UHFFFAOYSA-N	149724	US8975415, RP9a::US8975415, RP9b::US9242973, RP9b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149724&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056181	252159268							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361874	CCC1Oc2ccc(Br)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C15H17BrN2O3/c1-2-12-14(6-19-7-14)15(8-20-13(17)18-15)10-5-9(16)3-4-11(10)21-12/h3-5,12H,2,6-8H2,1H3,(H2,17,18)	UVKPJIHODHUWCZ-UHFFFAOYSA-N	149724	US8975415, RP9a::US8975415, RP9b::US9242973, RP9b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149724&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056181	252159268							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361875	NC1=NC2(CO1)c1cc(Br)ccc1OC1(CCCC1)C21COC1	InChI=1S/C17H19BrN2O3/c18-11-3-4-13-12(7-11)17(10-22-14(19)20-17)15(8-21-9-15)16(23-13)5-1-2-6-16/h3-4,7H,1-2,5-6,8-10H2,(H2,19,20)	DTJVAANWMRFEEX-UHFFFAOYSA-N	149726	US8975415, RP10::US9242973, RP10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149726&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056183	252159269							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361876	NC1=NC2(CO1)c1cc(Br)ccc1OC(Cc1ccccc1)C21COC1	InChI=1S/C20H19BrN2O3/c21-14-6-7-16-15(9-14)20(12-25-18(22)23-20)19(10-24-11-19)17(26-16)8-13-4-2-1-3-5-13/h1-7,9,17H,8,10-12H2,(H2,22,23)	GSLXZIRPXIIFQZ-UHFFFAOYSA-N	149735	US8975415, RP15a::US8975415, RP15b::US9242973, RP15b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149735&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056190	252159274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361877	NC1=NC2(CO1)c1cc(Br)ccc1OC(Cc1ccccc1)C21COC1	InChI=1S/C20H19BrN2O3/c21-14-6-7-16-15(9-14)20(12-25-18(22)23-20)19(10-24-11-19)17(26-16)8-13-4-2-1-3-5-13/h1-7,9,17H,8,10-12H2,(H2,22,23)	GSLXZIRPXIIFQZ-UHFFFAOYSA-N	149735	US8975415, RP15a::US8975415, RP15b::US9242973, RP15b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7930							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149735&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056190	252159274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361878	NC1=NC2(CO1)c1cc(Br)ccc1OC(CC1CC1)C21COC1	InChI=1S/C17H19BrN2O3/c18-11-3-4-13-12(6-11)17(9-22-15(19)20-17)16(7-21-8-16)14(23-13)5-10-1-2-10/h3-4,6,10,14H,1-2,5,7-9H2,(H2,19,20)	FKWYDOXONAHPDE-UHFFFAOYSA-N	149737	US8975415, RP16a::US8975415, RP16b::US9242973, RP16b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149737&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056184	252159275							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361879	NC1=NC2(CO1)c1cc(Br)ccc1OC(CC1CC1)C21COC1	InChI=1S/C17H19BrN2O3/c18-11-3-4-13-12(6-11)17(9-22-15(19)20-17)16(7-21-8-16)14(23-13)5-10-1-2-10/h3-4,6,10,14H,1-2,5,7-9H2,(H2,19,20)	FKWYDOXONAHPDE-UHFFFAOYSA-N	149737	US8975415, RP16a::US8975415, RP16b::US9242973, RP16b	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149737&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056184	252159275							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361880	NC1=NC2(CO1)c1cc(Br)ccc1OCC21CC1	InChI=1S/C13H13BrN2O2/c14-8-1-2-10-9(5-8)13(7-18-11(15)16-13)12(3-4-12)6-17-10/h1-2,5H,3-4,6-7H2,(H2,15,16)	PRFPBWPICIUVRO-UHFFFAOYSA-N	149739	US8975415, RP17::US9242973, RP17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724231	252159276							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361881	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	INWIVMOTHPFWNU-UHFFFAOYSA-N	149749	US8975415, 27::US9242973, 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149749&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548694	252159286							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361882	CC1(C)Oc2ccc(NC(=O)c3ccc(F)cn3)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C21H21FN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)	FSJTVQBTRXXXMC-UHFFFAOYSA-N	149750	US8975415, 28::US9242973, 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548695	252159287							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361883	NC1=NC2(CO1)c1cc(NC(=O)c3ncc(Cl)cc3F)ccc1OCC21CC1	InChI=1S/C19H16ClFN4O3/c20-10-5-13(21)15(23-7-10)16(26)24-11-1-2-14-12(6-11)19(9-28-17(22)25-19)18(3-4-18)8-27-14/h1-2,5-7H,3-4,8-9H2,(H2,22,25)(H,24,26)	BAZZVTQQQIAGLD-UHFFFAOYSA-N	149751	US8975415, RP29::US9242973, RP29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056150	252159288							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361884	CC1(C)Oc2ccc(NC(=O)c3ncc(Cl)cc3F)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C21H20ClFN4O4/c1-19(2)20(8-29-9-20)21(10-30-18(24)27-21)13-6-12(3-4-15(13)31-19)26-17(28)16-14(23)5-11(22)7-25-16/h3-7H,8-10H2,1-2H3,(H2,24,27)(H,26,28)	NNCFJTIUQAEALJ-UHFFFAOYSA-N	149752	US8975415, 30::US9242973, 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548696	252159289							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361885	NC1=NC2(CO1)c1cc(NC(=O)c3ccc(F)cn3)ccc1OCC21CC1	InChI=1S/C19H17FN4O3/c20-11-1-3-14(22-8-11)16(25)23-12-2-4-15-13(7-12)19(10-27-17(21)24-19)18(5-6-18)9-26-15/h1-4,7-8H,5-6,9-10H2,(H2,21,24)(H,23,25)	SGURBDAGQXAXNV-UHFFFAOYSA-N	149753	US8975415, RP31::US9242973, RP31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149753&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724294	252159290							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361886	NC1=NC2(CO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1OCC21CC1	InChI=1S/C19H17ClN4O3/c20-11-1-3-14(22-8-11)16(25)23-12-2-4-15-13(7-12)19(10-27-17(21)24-19)18(5-6-18)9-26-15/h1-4,7-8H,5-6,9-10H2,(H2,21,24)(H,23,25)	ASXIBZVBBQRBMI-UHFFFAOYSA-N	149754	US8975415, RP32::US9242973, RP32	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2170							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149754&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056233	252159291							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361887	NC1=NC2(CO1)c1cc(ccc1OCC21COC1)-c1cc(Cl)cnc1F	InChI=1S/C18H15ClFN3O3/c19-11-4-12(15(20)22-5-11)10-1-2-14-13(3-10)18(9-26-16(21)23-18)17(8-25-14)6-24-7-17/h1-5H,6-9H2,(H2,21,23)	OXWANDFSWNCOLM-UHFFFAOYSA-N	149756	US8975415, RP34::US9242973, RP34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149756	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149756&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246706	252159293							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361888	CC1(C)Oc2ccc(Br)cc2C2(CSC(N)=N2)C11COC1	InChI=1S/C15H17BrN2O2S/c1-13(2)14(6-19-7-14)15(8-21-12(17)18-15)10-5-9(16)3-4-11(10)20-13/h3-5H,6-8H2,1-2H3,(H2,17,18)	FXWBDJSWBRAHBD-UHFFFAOYSA-N	149763	US8975415, RP42::US9242973, RP42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149763	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149763&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056326	252159300							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361889	NC1=NC2(CO1)c1cc(Nc3ncccc3Cl)ccc1OCC21COC1	InChI=1S/C18H17ClN4O3/c19-13-2-1-5-21-15(13)22-11-3-4-14-12(6-11)18(10-26-16(20)23-18)17(9-25-14)7-24-8-17/h1-6H,7-10H2,(H2,20,23)(H,21,22)	XNPBNQHTEMDPQV-UHFFFAOYSA-N	149764	US8975415, RP43::US9242973, RP43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149764	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149764&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724298	252159301							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361890	COc1cccnc1Nc1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C22H24N4O4/c1-27-17-4-2-9-24-18(17)25-14-5-6-16-15(10-14)22(13-29-19(23)26-22)20(11-28-12-20)21(30-16)7-3-8-21/h2,4-6,9-10H,3,7-8,11-13H2,1H3,(H2,23,26)(H,24,25)	WWHBQSJSWHAQSI-UHFFFAOYSA-N	149766	US8975415, RP45::US9242973, RP45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149766&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056328	252159303							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361891	CC(C)Cc1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C20H26N2O3/c1-13(2)8-14-4-5-16-15(9-14)20(12-24-17(21)22-20)18(10-23-11-18)19(25-16)6-3-7-19/h4-5,9,13H,3,6-8,10-12H2,1-2H3,(H2,21,22)	DRTDEDKNDXQLDZ-UHFFFAOYSA-N	149767	US8975415, RP46::US9242973, RP46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149767	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149767&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724299	252159304							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361892	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C19H20N4O3/c1-17(2)18(8-24-9-18)19(10-25-16(20)23-19)14-5-12(3-4-15(14)26-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	WRPYZOUQPVZQFZ-UHFFFAOYSA-N	149770	US8975415, RP51a::US8975415, RP51b::US8975415, RP69::US9242973, RP69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025104	252159307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361893	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C19H20N4O3/c1-17(2)18(8-24-9-18)19(10-25-16(20)23-19)14-5-12(3-4-15(14)26-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	WRPYZOUQPVZQFZ-UHFFFAOYSA-N	149770	US8975415, RP51a::US8975415, RP51b::US8975415, RP69::US9242973, RP69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025104	252159307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361894	CC#Cc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H19N3O2/c1-2-3-14-8-16(11-23-10-14)15-4-5-18-17(9-15)21(13-26-19(22)24-21)20(6-7-20)12-25-18/h4-5,8-11H,6-7,12-13H2,1H3,(H2,22,24)	ZKVKPYPCNDJJIH-UHFFFAOYSA-N	149772	US8975415, RP111::US8975415, RP52a::US9242973, RP111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4830							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90016739	252159308							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361895	CC#Cc1cncc(c1)-c1ccc2OCC3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H19N3O3/c1-2-3-14-6-16(9-23-8-14)15-4-5-18-17(7-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	KPXCLUUQECRYFF-UHFFFAOYSA-N	149773	US8975415, RP108::US8975415, RP53b::US9242973, RP108	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724311	252159309							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361896	CC1(C)Oc2ccc(cc2C2(CSC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C19H20N4O2S/c1-17(2)18(8-24-9-18)19(10-26-16(20)23-19)14-5-12(3-4-15(14)25-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	DGIBRPPLNYXLMV-UHFFFAOYSA-N	149774	US8975415, RP54::US9242973, RP54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724304	252159310							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361897	CC#Cc1ccnc(c1)-c1ccc2OCC3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H19N3O3/c1-2-3-14-6-7-23-17(8-14)15-4-5-18-16(9-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	FONNNDYVWDWHRD-UHFFFAOYSA-N	149775	US8975415, RP56::US9242973, RP56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149775&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90055131	252159311							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361898	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(c1)C1CC1	InChI=1S/C21H21N3O2/c22-19-24-21(12-26-19)17-8-14(3-4-18(17)25-11-20(21)5-6-20)16-7-15(9-23-10-16)13-1-2-13/h3-4,7-10,13H,1-2,5-6,11-12H2,(H2,22,24)	DFEWHEYFZREFMD-UHFFFAOYSA-N	149776	US8975415, RP57::US9242973, RP57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3480							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149776&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246708	252159312							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361899	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OCC(F)(F)F)c1	InChI=1S/C20H18F3N3O3/c21-20(22,23)11-27-14-5-13(7-25-8-14)12-1-2-16-15(6-12)19(10-29-17(24)26-19)18(3-4-18)9-28-16/h1-2,5-8H,3-4,9-11H2,(H2,24,26)	PBIVNBDJISSSOF-UHFFFAOYSA-N	149777	US8975415, RP58::US9242973, RP58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5810							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149777&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246709	252159313							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361900	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OCC(F)F)c1	InChI=1S/C20H19F2N3O3/c21-17(22)9-26-14-5-13(7-24-8-14)12-1-2-16-15(6-12)20(11-28-18(23)25-20)19(3-4-19)10-27-16/h1-2,5-8,17H,3-4,9-11H2,(H2,23,25)	WQKBRYBBAYLSSQ-UHFFFAOYSA-N	149778	US8975415, RP59::US9242973, RP59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6900							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149778&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246710	252159314							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361901	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OC(F)F)c1	InChI=1S/C19H17F2N3O3/c20-16(21)27-13-5-12(7-23-8-13)11-1-2-15-14(6-11)19(10-26-17(22)24-19)18(3-4-18)9-25-15/h1-2,5-8,16H,3-4,9-10H2,(H2,22,24)	UNYXJDJEOAZPJZ-UHFFFAOYSA-N	149779	US8975415, RP60::US9242973, RP60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2780							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149779&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90055135	252159315							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361902	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cnc2[nH]ccc2c1			149780	US8975415, RP61::US9242973, RP61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9220							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149780&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724307	252159316							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361903	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cnc2[nH]cc(Cl)c2c1			149781	US8975415, RP62::US9242973, RP62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4430							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149781	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149781&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90249017	252159317							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361904	CCc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C20H21N3O2/c1-2-13-7-15(10-22-9-13)14-3-4-17-16(8-14)20(12-25-18(21)23-20)19(5-6-19)11-24-17/h3-4,7-10H,2,5-6,11-12H2,1H3,(H2,21,23)	ACFKJXYIJBZGDF-UHFFFAOYSA-N	149782	US8975415, RP63::US9242973, RP63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4480							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149782	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149782&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246712	252159318							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361905	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(OCC(F)(F)C(F)F)c1	InChI=1S/C21H19F4N3O3/c22-17(23)21(24,25)11-29-14-5-13(7-27-8-14)12-1-2-16-15(6-12)20(10-31-18(26)28-20)19(3-4-19)9-30-16/h1-2,5-8,17H,3-4,9-11H2,(H2,26,28)	DSXZHBCAGPUTHY-UHFFFAOYSA-N	149783	US8975415, RP64::US9242973, RP64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1670							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149783	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149783&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246711	252159319							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361906	COc1ccnc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H23N3O4/c1-19(2)20(10-26-11-20)21(12-27-18(22)24-21)15-8-13(4-5-17(15)28-19)16-9-14(25-3)6-7-23-16/h4-9H,10-12H2,1-3H3,(H2,22,24)	VODDOGVAQARPID-UHFFFAOYSA-N	149784	US8975415, RP65::US9242973, RP65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9770							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149784&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724309	252159320							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361907	Cc1cn2ccc(cc2n1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C24H24N4O3/c1-15-11-28-8-5-17(10-20(28)26-15)16-3-4-19-18(9-16)24(14-30-21(25)27-24)22(12-29-13-22)23(31-19)6-2-7-23/h3-5,8-11H,2,6-7,12-14H2,1H3,(H2,25,27)	YXGIXUOSNXEEFY-UHFFFAOYSA-N	149785	US8975415, RP66::US9242973, RP66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056473	252159321							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361908	Cc1cn2cc(ccc2n1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C24H24N4O3/c1-15-10-28-11-17(4-6-20(28)26-15)16-3-5-19-18(9-16)24(14-30-21(25)27-24)22(12-29-13-22)23(31-19)7-2-8-23/h3-6,9-11H,2,7-8,12-14H2,1H3,(H2,25,27)	JKGOTVHTXJKXLS-UHFFFAOYSA-N	149786	US8975415, RP67::US9242973, RP67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90017611	252159322							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361909	CC#Cc1cncc(c1)-c1ccc2OCC3(COC3)C3(CSC(N)=N3)c2c1	InChI=1S/C21H19N3O2S/c1-2-3-14-6-16(9-23-8-14)15-4-5-18-17(7-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	SUTVFEFTMJCRDP-UHFFFAOYSA-N	149787	US8975415, RP68::US9242973, RP68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6050							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149787&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246713	252159323							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361910	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C19H20N4O3/c1-17(2)18(8-24-9-18)19(10-25-16(20)23-19)14-5-12(3-4-15(14)26-17)13-6-21-11-22-7-13/h3-7,11H,8-10H2,1-2H3,(H2,20,23)	WRPYZOUQPVZQFZ-UHFFFAOYSA-N	149770	US8975415, RP51a::US8975415, RP51b::US8975415, RP69::US9242973, RP69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025104	252159307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361911	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc(F)c1	InChI=1S/C21H20FN3O3/c22-15-6-14(8-24-9-15)13-2-3-17-16(7-13)21(12-27-18(23)25-21)19(10-26-11-19)20(28-17)4-1-5-20/h2-3,6-9H,1,4-5,10-12H2,(H2,23,25)	VKXZBNSASBAXPO-UHFFFAOYSA-N	149789	US8975415, RP70::US9242973, RP70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246714	252159324							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361912	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1F	InChI=1S/C21H20FN3O3/c22-17-14(3-1-8-24-17)13-4-5-16-15(9-13)21(12-27-18(23)25-21)19(10-26-11-19)20(28-16)6-2-7-20/h1,3-5,8-9H,2,6-7,10-12H2,(H2,23,25)	MIWGEPYDEJPCPW-UHFFFAOYSA-N	149790	US8975415, RP71::US9242973, RP71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149790&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246716	252159325							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361913	COc1cncc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C22H23N3O4/c1-26-16-7-15(9-24-10-16)14-3-4-18-17(8-14)22(13-28-19(23)25-22)20(11-27-12-20)21(29-18)5-2-6-21/h3-4,7-10H,2,5-6,11-13H2,1H3,(H2,23,25)	OKGLRFINLNSCOR-UHFFFAOYSA-N	149791	US8975415, RP72::US9242973, RP72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8220							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149791&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246715	252159326							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361914	Cc1cncc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C22H23N3O3/c1-14-7-16(10-24-9-14)15-3-4-18-17(8-15)22(13-27-19(23)25-22)20(11-26-12-20)21(28-18)5-2-6-21/h3-4,7-10H,2,5-6,11-13H2,1H3,(H2,23,25)	XVSNEAWVASTHHT-UHFFFAOYSA-N	149794	US8975415, RP75::US9242973, RP75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149794&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025147	252159329							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361915	Cc1cnnc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H22N4O3/c1-13-7-16(25-23-9-13)14-3-4-17-15(8-14)21(12-27-18(22)24-21)19(10-26-11-19)20(28-17)5-2-6-20/h3-4,7-9H,2,5-6,10-12H2,1H3,(H2,22,24)	CENZKPKDVOYGAD-UHFFFAOYSA-N	149795	US8975415, RP76::US9242973, RP76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149795&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246718	252159330							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361916	C[C@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cccnc1F	InChI=1S/C19H18FN3O3/c1-11-18(8-24-9-18)19(10-25-17(21)23-19)14-7-12(4-5-15(14)26-11)13-3-2-6-22-16(13)20/h2-7,11H,8-10H2,1H3,(H2,21,23)/t11-,19+/m1/s1	GBWBGGRZIJBHOV-WYRIXSBYSA-N	149796	US8975415, RP77::US9242973, RP77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149796&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246719	252159331							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361917	C[C@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C18H18N4O3/c1-11-17(7-23-8-17)18(9-24-16(19)22-18)14-4-12(2-3-15(14)25-11)13-5-20-10-21-6-13/h2-6,10-11H,7-9H2,1H3,(H2,19,22)/t11-,18+/m1/s1	VFWRHIJUHBWEBW-ZMZPIMSZSA-N	149797	US8975415, RP78::US9242973, RP78	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149797&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056135	252159332							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361918	C[C@@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cccnc1F	InChI=1S/C19H18FN3O3/c1-11-18(8-24-9-18)19(10-25-17(21)23-19)14-7-12(4-5-15(14)26-11)13-3-2-6-22-16(13)20/h2-7,11H,8-10H2,1H3,(H2,21,23)/t11-,19-/m0/s1	GBWBGGRZIJBHOV-WLRWDXFRSA-N	149798	US8975415, RP79::US9242973, RP79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149798&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056142	252159333							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361919	C[C@@H]1Oc2ccc(cc2[C@@]2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C18H18N4O3/c1-11-17(7-23-8-17)18(9-24-16(19)22-18)14-4-12(2-3-15(14)25-11)13-5-20-10-21-6-13/h2-6,10-11H,7-9H2,1H3,(H2,19,22)/t11-,18-/m0/s1	VFWRHIJUHBWEBW-VOJFVSQTSA-N	149799	US8975415, RP80::US9242973, RP80	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149799&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056134	252159334							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361920	COc1cncc(c1)-c1ccc2O[C@H](C)C3(COC3)[C@]3(COC(N)=N3)c2c1	InChI=1S/C20H21N3O4/c1-12-19(9-25-10-19)20(11-26-18(21)23-20)16-6-13(3-4-17(16)27-12)14-5-15(24-2)8-22-7-14/h3-8,12H,9-11H2,1-2H3,(H2,21,23)/t12-,20+/m1/s1	FODVISLDJAALAH-ODXCJYRJSA-N	149800	US8975415, RP81::US9242973, RP81	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149800&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246720	252159335							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361921	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cccnc1F	InChI=1S/C20H20FN3O3/c1-18(2)19(9-25-10-19)20(11-26-17(22)24-20)14-8-12(5-6-15(14)27-18)13-4-3-7-23-16(13)21/h3-8H,9-11H2,1-2H3,(H2,22,24)	AVGCDLOTQSAMEY-UHFFFAOYSA-N	149801	US8975415, RP82::US9242973, RP82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149801&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246721	252159336							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361922	COc1cncc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H23N3O4/c1-19(2)20(10-26-11-20)21(12-27-18(22)24-21)16-7-13(4-5-17(16)28-19)14-6-15(25-3)9-23-8-14/h4-9H,10-12H2,1-3H3,(H2,22,24)	IAWZSEUFAASPLV-UHFFFAOYSA-N	149802	US8975415, RP83::US9242973, RP83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149802&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246722	252159337							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361923	CCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C19H20N4O3/c1-2-16-18(8-24-9-18)19(10-25-17(20)23-19)14-5-12(3-4-15(14)26-16)13-6-21-11-22-7-13/h3-7,11,16H,2,8-10H2,1H3,(H2,20,23)	ZMBYVIVIUYRASD-UHFFFAOYSA-N	149803	US8975415, RP84::US8975415, RP87::US9242973, RP84	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149803&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246723	252159338							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361924	NC1=NC2(CO1)c1cc(ccc1OC1(CCCC1)C21COC1)-c1cncnc1	InChI=1S/C21H22N4O3/c22-18-25-21(12-27-18)16-7-14(15-8-23-13-24-9-15)3-4-17(16)28-20(5-1-2-6-20)19(21)10-26-11-19/h3-4,7-9,13H,1-2,5-6,10-12H2,(H2,22,25)	STXYCGOXMYPZGQ-UHFFFAOYSA-N	149804	US8975415, RP85::US9242973, RP85	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149804&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056138	252159339							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361925	CCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#CC	InChI=1S/C23H23N3O3/c1-3-5-15-8-17(11-25-10-15)16-6-7-19-18(9-16)23(14-28-21(24)26-23)22(12-27-13-22)20(4-2)29-19/h6-11,20H,4,12-14H2,1-2H3,(H2,24,26)	YOCKQJMJWGYCKD-UHFFFAOYSA-N	149805	US8975415, RP86::US9242973, RP86	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7940							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246724	252159340							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361926	NC1=NC2(CO1)c1cc(ccc1OC(C1CC1)C21COC1)-c1cncnc1	InChI=1S/C20H20N4O3/c21-18-24-20(10-26-18)15-5-13(14-6-22-11-23-7-14)3-4-16(15)27-17(12-1-2-12)19(20)8-25-9-19/h3-7,11-12,17H,1-2,8-10H2,(H2,21,24)	LHAFHTSWDCBCED-UHFFFAOYSA-N	149807	US8975415, RP88::US8975415, RP89::US9242973, RP89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056144	252159341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361927	NC1=NC2(CO1)c1cc(ccc1OC(C1CC1)C21COC1)-c1cncnc1	InChI=1S/C20H20N4O3/c21-18-24-20(10-26-18)15-5-13(14-6-22-11-23-7-14)3-4-16(15)27-17(12-1-2-12)19(20)8-25-9-19/h3-7,11-12,17H,1-2,8-10H2,(H2,21,24)	LHAFHTSWDCBCED-UHFFFAOYSA-N	149807	US8975415, RP88::US8975415, RP89::US9242973, RP89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056144	252159341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361928	CC(C)CC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C21H24N4O3/c1-13(2)5-18-20(9-26-10-20)21(11-27-19(22)25-21)16-6-14(3-4-17(16)28-18)15-7-23-12-24-8-15/h3-4,6-8,12-13,18H,5,9-11H2,1-2H3,(H2,22,25)	QQPOTGIGKATGCB-UHFFFAOYSA-N	149809	US8975415, RP90::US8975415, RP93::US9242973, RP93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246725	252159342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361929	CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C20H22N4O3/c1-2-3-17-19(9-25-10-19)20(11-26-18(21)24-20)15-6-13(4-5-16(15)27-17)14-7-22-12-23-8-14/h4-8,12,17H,2-3,9-11H2,1H3,(H2,21,24)	XGNRRAYBEHJJDH-UHFFFAOYSA-N	149810	US8975415, RP91::US8975415, RP94::US9242973, RP94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149810&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056255	252159343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361930	CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#CC	InChI=1S/C24H25N3O3/c1-3-5-16-9-18(12-26-11-16)17-7-8-20-19(10-17)24(15-29-22(25)27-24)23(13-28-14-23)21(30-20)6-4-2/h7-12,21H,4,6,13-15H2,1-2H3,(H2,25,27)	VKNCKYKSIFQAIK-UHFFFAOYSA-N	149811	US8975415, RP92::US9242973, RP92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5340							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149811&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246726	252159344							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361931	CC(C)CC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C21H24N4O3/c1-13(2)5-18-20(9-26-10-20)21(11-27-19(22)25-21)16-6-14(3-4-17(16)28-18)15-7-23-12-24-8-15/h3-4,6-8,12-13,18H,5,9-11H2,1-2H3,(H2,22,25)	QQPOTGIGKATGCB-UHFFFAOYSA-N	149809	US8975415, RP90::US8975415, RP93::US9242973, RP93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246725	252159342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361932	CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncnc1	InChI=1S/C20H22N4O3/c1-2-3-17-19(9-25-10-19)20(11-26-18(21)24-20)15-6-13(4-5-16(15)27-17)14-7-22-12-23-8-14/h4-8,12,17H,2-3,9-11H2,1H3,(H2,21,24)	XGNRRAYBEHJJDH-UHFFFAOYSA-N	149810	US8975415, RP91::US8975415, RP94::US9242973, RP94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149810&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056255	252159343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361933	NC1=NC2(CO1)c1cc(ccc1OC(CCC(F)(F)F)C21COC1)-c1cncnc1	InChI=1S/C20H19F3N4O3/c21-20(22,23)4-3-16-18(8-28-9-18)19(10-29-17(24)27-19)14-5-12(1-2-15(14)30-16)13-6-25-11-26-7-13/h1-2,5-7,11,16H,3-4,8-10H2,(H2,24,27)	SIJQFJDBAGZTQE-UHFFFAOYSA-N	203883	US9242973, RP95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=203883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=203883&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056256	319565079							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361934	CC#Cc1cncc(c1)-c1ccc2OC(CCC(F)(F)F)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C24H22F3N3O3/c1-2-3-15-8-17(11-29-10-15)16-4-5-19-18(9-16)23(14-32-21(28)30-23)22(12-31-13-22)20(33-19)6-7-24(25,26)27/h4-5,8-11,20H,6-7,12-14H2,1H3,(H2,28,30)	LMEWGQSCAOBUKB-UHFFFAOYSA-N	149815	US8975415, RP96::US9242973, RP96	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149815&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246728	252159346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361935	NC1=NC2(CO1)c1cc(ccc1OCC21CCCO1)-c1cncnc1	InChI=1S/C18H18N4O3/c19-16-22-18(10-24-16)14-6-12(13-7-20-11-21-8-13)2-3-15(14)23-9-17(18)4-1-5-25-17/h2-3,6-8,11H,1,4-5,9-10H2,(H2,19,22)	DMEXFXDUGPEWQS-UHFFFAOYSA-N	149816	US8975415, RP97::US8975415, RP98::US9242973, RP98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149816&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246729	252159347							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361936	NC1=NC2(CO1)c1cc(ccc1OCC21CCCO1)-c1cncnc1	InChI=1S/C18H18N4O3/c19-16-22-18(10-24-16)14-6-12(13-7-20-11-21-8-13)2-3-15(14)23-9-17(18)4-1-5-25-17/h2-3,6-8,11H,1,4-5,9-10H2,(H2,19,22)	DMEXFXDUGPEWQS-UHFFFAOYSA-N	149816	US8975415, RP97::US8975415, RP98::US9242973, RP98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149816&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246729	252159347							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361937	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc(c1)C(F)(F)F	InChI=1S/C22H20F3N3O3/c23-22(24,25)15-6-14(8-27-9-15)13-2-3-17-16(7-13)21(12-30-18(26)28-21)19(10-29-11-19)20(31-17)4-1-5-20/h2-3,6-9H,1,4-5,10-12H2,(H2,26,28)	DNXRXHBBOSWKEH-UHFFFAOYSA-N	149818	US8975415, RP99::US9242973, RP99	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149818&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056251	252159348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361938	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncnc1	InChI=1S/C17H16N4O2/c18-15-21-17(9-23-15)13-5-11(12-6-19-10-20-7-12)1-2-14(13)22-8-16(17)3-4-16/h1-2,5-7,10H,3-4,8-9H2,(H2,18,21)	GQFYFTNDSLXGAN-UHFFFAOYSA-N	149819	US8975415, RP100::US9242973, RP100	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149819&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056261	252159349							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361939	NC1=NC2(CO1)c1cc(ccc1OCC21CCC1)-c1cncnc1	InChI=1S/C18H18N4O2/c19-16-22-18(10-24-16)14-6-12(13-7-20-11-21-8-13)2-3-15(14)23-9-17(18)4-1-5-17/h2-3,6-8,11H,1,4-5,9-10H2,(H2,19,22)	AOHYTTMQYWIGBI-UHFFFAOYSA-N	149820	US8975415, RP101::US9242973, RP101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5280							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056252	252159350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361940	NC1=NC2(CO1)c1cc(c(F)cc1OCC21CC1)-c1cncnc1	InChI=1S/C17H15FN4O2/c18-13-4-14-12(3-11(13)10-5-20-9-21-6-10)17(8-24-15(19)22-17)16(1-2-16)7-23-14/h3-6,9H,1-2,7-8H2,(H2,19,22)	LZIPIZWOUYFZDB-UHFFFAOYSA-N	149821	US8975415, RP102::US9242973, RP102	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149821&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056259	252159351							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361941	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cccnc1F	InChI=1S/C18H16FN3O2/c19-15-12(2-1-7-21-15)11-3-4-14-13(8-11)18(10-24-16(20)22-18)17(5-6-17)9-23-14/h1-4,7-8H,5-6,9-10H2,(H2,20,22)	HAVSLFQSSPEGTD-UHFFFAOYSA-N	149822	US8975415, RP103::US9242973, RP103	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149822&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056258	252159352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361942	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cc(Cl)cnc1F	InChI=1S/C18H15ClFN3O2/c19-11-6-12(15(20)22-7-11)10-1-2-14-13(5-10)18(9-25-16(21)23-18)17(3-4-17)8-24-14/h1-2,5-7H,3-4,8-9H2,(H2,21,23)	YLFDDYWNYJPIAU-UHFFFAOYSA-N	149823	US8975415, RP104::US9242973, RP104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3250							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149823&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056260	252159353							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361943	COc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C19H19N3O3/c1-23-14-6-13(8-21-9-14)12-2-3-16-15(7-12)19(11-25-17(20)22-19)18(4-5-18)10-24-16/h2-3,6-9H,4-5,10-11H2,1H3,(H2,20,22)	ZOGSWBUPTFGEHZ-UHFFFAOYSA-N	149824	US8975415, RP105::US9242973, RP105	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7900							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056199	252159354							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361944	CCOc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C20H21N3O3/c1-2-24-15-7-14(9-22-10-15)13-3-4-17-16(8-13)20(12-26-18(21)23-20)19(5-6-19)11-25-17/h3-4,7-10H,2,5-6,11-12H2,1H3,(H2,21,23)	ZBXSCAQSUCUQMO-UHFFFAOYSA-N	149825	US8975415, RP106::US9242973, RP106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5750							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149825&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246730	252159355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361945	NC1=NC2(CO1)c1cc(ccc1OCC21CC1)-c1cncc(Cl)c1	InChI=1S/C18H16ClN3O2/c19-13-5-12(7-21-8-13)11-1-2-15-14(6-11)18(10-24-16(20)22-18)17(3-4-17)9-23-15/h1-2,5-8H,3-4,9-10H2,(H2,20,22)	WMZFHEUJJBBJRB-UHFFFAOYSA-N	149826	US8975415, RP107::US9242973, RP107	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2910							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149826&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056194	252159356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361946	CC#Cc1cncc(c1)-c1ccc2OCC3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H19N3O3/c1-2-3-14-6-16(9-23-8-14)15-4-5-18-17(7-15)21(13-27-19(22)24-21)20(12-26-18)10-25-11-20/h4-9H,10-13H2,1H3,(H2,22,24)	KPXCLUUQECRYFF-UHFFFAOYSA-N	149773	US8975415, RP108::US8975415, RP53b::US9242973, RP108	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9400							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724311	252159309							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361947	CC#Cc1cncc(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C24H23N3O3/c1-2-4-16-9-18(12-26-11-16)17-5-6-20-19(10-17)24(15-29-21(25)27-24)22(13-28-14-22)23(30-20)7-3-8-23/h5-6,9-12H,3,7-8,13-15H2,1H3,(H2,25,27)	NPOSFNQEFRRESB-UHFFFAOYSA-N	149828	US8975415, RP109::US9242973, RP109	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246731	252159357							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361948	CC#Cc1cncc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C23H23N3O3/c1-4-5-15-8-17(11-25-10-15)16-6-7-19-18(9-16)23(14-28-20(24)26-23)22(12-27-13-22)21(2,3)29-19/h6-11H,12-14H2,1-3H3,(H2,24,26)	TWNMFZUXTQLPDM-UHFFFAOYSA-N	149829	US8975415, RP110::US9242973, RP110	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149829&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056237	252159358							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361949	CC#Cc1cncc(c1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H19N3O2/c1-2-3-14-8-16(11-23-10-14)15-4-5-18-17(9-15)21(13-26-19(22)24-21)20(6-7-20)12-25-18/h4-5,8-11H,6-7,12-13H2,1H3,(H2,22,24)	ZKVKPYPCNDJJIH-UHFFFAOYSA-N	149772	US8975415, RP111::US8975415, RP52a::US9242973, RP111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1980							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90016739	252159308							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361950	CC#Cc1cncc(c1)-c1cc2c(OCC3(CC3)C22COC(N)=N2)cc1F	InChI=1S/C21H18FN3O2/c1-2-3-13-6-14(10-24-9-13)15-7-16-18(8-17(15)22)26-11-20(4-5-20)21(16)12-27-19(23)25-21/h6-10H,4-5,11-12H2,1H3,(H2,23,25)	GYSSPZTVUHYMLA-UHFFFAOYSA-N	149831	US8975415, RP112::US9242973, RP112	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4320							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246732	252159359							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361951	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1C#N	InChI=1S/C22H20N4O3/c23-10-17-15(3-1-8-25-17)14-4-5-18-16(9-14)22(13-28-19(24)26-22)20(11-27-12-20)21(29-18)6-2-7-21/h1,3-5,8-9H,2,6-7,11-13H2,(H2,24,26)	UGLJAYTUNCDFRY-UHFFFAOYSA-N	149834	US8975415, RP115::US9242973, RP115	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025658	252159362							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361952	Cc1cnc(F)c(c1)-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C22H22FN3O3/c1-13-7-15(18(23)25-9-13)14-3-4-17-16(8-14)22(12-28-19(24)26-22)20(10-27-11-20)21(29-17)5-2-6-21/h3-4,7-9H,2,5-6,10-12H2,1H3,(H2,24,26)	RUUFULDNAISCMR-UHFFFAOYSA-N	149835	US8975415, RP116::US9242973, RP116	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149835&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90026778	252159363							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361953	Cc1ncncc1-c1ccc2OC3(CCC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H22N4O3/c1-13-15(8-23-12-24-13)14-3-4-17-16(7-14)21(11-27-18(22)25-21)19(9-26-10-19)20(28-17)5-2-6-20/h3-4,7-8,12H,2,5-6,9-11H2,1H3,(H2,22,25)	ZNEBJRVYFYIQSP-UHFFFAOYSA-N	149836	US8975415, RP117::US9242973, RP117	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149836&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246734	252159364							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361954	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc(c1)C(F)F	InChI=1S/C22H21F2N3O3/c23-18(24)15-6-14(8-26-9-15)13-2-3-17-16(7-13)22(12-29-19(25)27-22)20(10-28-11-20)21(30-17)4-1-5-21/h2-3,6-9,18H,1,4-5,10-12H2,(H2,25,27)	HSUAECWUMSPRSF-UHFFFAOYSA-N	149837	US8975415, RP118::US9242973, RP118	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149837&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056204	252159365							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361955	COc1cccc(c1)-c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C22H24N2O4/c1-20(2)21(11-26-12-21)22(13-27-19(23)24-22)17-10-15(7-8-18(17)28-20)14-5-4-6-16(9-14)25-3/h4-10H,11-13H2,1-3H3,(H2,23,24)	NTYCQRSCQKAIKY-UHFFFAOYSA-N	149861	US8975415, RP142::US9242973, RP142	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149861&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246736	252159389							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361956	CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cc(Cl)cnc1F	InChI=1S/C20H19ClFN3O3/c1-18(2)19(8-26-9-19)20(10-27-17(23)25-20)14-5-11(3-4-15(14)28-18)13-6-12(21)7-24-16(13)22/h3-7H,8-10H2,1-2H3,(H2,23,25)	GETMSLAWJGDJFJ-UHFFFAOYSA-N	149873	US8975415, RP154::US9242973, RP154	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056479	252159401							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361957	NC1=NC2(CO1)c1cc(Br)ccc1OCC21CC(F)(F)C1	InChI=1S/C14H13BrF2N2O2/c15-8-1-2-10-9(3-8)14(7-21-11(18)19-14)12(6-20-10)4-13(16,17)5-12/h1-3H,4-7H2,(H2,18,19)	UWKRYKVCCZEOQP-UHFFFAOYSA-N	149907	US8975415, RP188::US9242973, RP188	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149907	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149907&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056348	252159435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361958	NC1=NC2(CO1)c1cc(NC(=O)c3ncc(Br)cn3)ccc1OCC21CC1	InChI=1S/C18H16BrN5O3/c19-10-6-21-14(22-7-10)15(25)23-11-1-2-13-12(5-11)18(9-27-16(20)24-18)17(3-4-17)8-26-13/h1-2,5-7H,3-4,8-9H2,(H2,20,24)(H,23,25)	RUPHOSKJXJYHAD-UHFFFAOYSA-N	149908	US8975415, RP189::US9242973, RP189	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149908	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149908&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056336	252159436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361959	CC1(C)Oc2ccc(NC(=O)c3ncc(Br)cn3)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C20H20BrN5O4/c1-18(2)19(8-28-9-19)20(10-29-17(22)26-20)13-5-12(3-4-14(13)30-18)25-16(27)15-23-6-11(21)7-24-15/h3-7H,8-10H2,1-2H3,(H2,22,26)(H,25,27)	OKNLKKUCXCACGI-UHFFFAOYSA-N	149909	US8975415, RP190::US9242973, 190	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149909&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025105	252159437							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361960	Cc1cc(cnc1C(=O)Nc1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1)C#N	InChI=1S/C21H19N5O3/c1-12-6-13(8-22)9-24-17(12)18(27)25-14-2-3-16-15(7-14)21(11-29-19(23)26-21)20(4-5-20)10-28-16/h2-3,6-7,9H,4-5,10-11H2,1H3,(H2,23,26)(H,25,27)	LUKKVICWYPMUPG-UHFFFAOYSA-N	149910	US8975415, RP191::US9242973, RP191	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149910&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90248978	252159438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361961	NC1=NC2(CO1)c1cc(NC(=O)c3ncc(cc3Cl)C#N)ccc1OCC21CC1	InChI=1S/C20H16ClN5O3/c21-14-5-11(7-22)8-24-16(14)17(27)25-12-1-2-15-13(6-12)20(10-29-18(23)26-20)19(3-4-19)9-28-15/h1-2,5-6,8H,3-4,9-10H2,(H2,23,26)(H,25,27)	OBYNGUKQVYJXLG-UHFFFAOYSA-N	149911	US8975415, RP192::US9242973, RP192	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149911&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90248994	252159439							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361962	COc1cnc(cn1)C(=O)Nc1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C19H19N5O4/c1-26-15-8-21-13(7-22-15)16(25)23-11-2-3-14-12(6-11)19(10-28-17(20)24-19)18(4-5-18)9-27-14/h2-3,6-8H,4-5,9-10H2,1H3,(H2,20,24)(H,23,25)	IPNOFVHQRLOFQU-UHFFFAOYSA-N	149912	US8975415, RP193::US9242973, RP193	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149912&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056104	252159440							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361963	Cc1cc(Cl)cnc1C(=O)Nc1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C20H19ClN4O3/c1-11-6-12(21)8-23-16(11)17(26)24-13-2-3-15-14(7-13)20(10-28-18(22)25-20)19(4-5-19)9-27-15/h2-3,6-8H,4-5,9-10H2,1H3,(H2,22,25)(H,24,26)	UGPKGDXAPPRVIR-UHFFFAOYSA-N	149913	US8975415, RP194::US9242973, RP194	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4910							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149913&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056343	252159441							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361964	Cc1cc(Cl)cnc1C(=O)Nc1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C22H23ClN4O4/c1-12-6-13(23)8-25-17(12)18(28)26-14-4-5-16-15(7-14)22(11-30-19(24)27-22)21(9-29-10-21)20(2,3)31-16/h4-8H,9-11H2,1-3H3,(H2,24,27)(H,26,28)	WTTPTTMLIGTSRC-UHFFFAOYSA-N	149914	US8975415, RP195::US9242973, 195	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149914&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548944	252159442							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361965	NC1=NC2(CO1)c1cc(NC(=O)c3ccc(cn3)C#N)ccc1OCC21CC1	InChI=1S/C20H17N5O3/c21-8-12-1-3-15(23-9-12)17(26)24-13-2-4-16-14(7-13)20(11-28-18(22)25-20)19(5-6-19)10-27-16/h1-4,7,9H,5-6,10-11H2,(H2,22,25)(H,24,26)	FCSDLAQZROWWFP-UHFFFAOYSA-N	149915	US8975415, RP196::US9242973, RP196	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3650							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149915&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90248997	252159443							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361966	CC1(C)Oc2ccc(NC(=O)c3ccc(cn3)C#N)cc2C2(COC(N)=N2)C11COC1	InChI=1S/C22H21N5O4/c1-20(2)21(10-29-11-21)22(12-30-19(24)27-22)15-7-14(4-6-17(15)31-20)26-18(28)16-5-3-13(8-23)9-25-16/h3-7,9H,10-12H2,1-2H3,(H2,24,27)(H,26,28)	GPWZMCGYHYETLO-UHFFFAOYSA-N	149916	US8975415, RP197::US9242973, 197	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149916	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149916&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548945	252159444							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361967	NC1=NC2(c3cc(ccc3OCC22CC2)-c2cncnc2)C(F)(F)CS1	InChI=1S/C18H16F2N4OS/c19-17(20)9-26-15(21)24-18(17)13-5-11(12-6-22-10-23-7-12)1-2-14(13)25-8-16(18)3-4-16/h1-2,5-7,10H,3-4,8-9H2,(H2,21,24)	UMLIDFYGFDMIGZ-UHFFFAOYSA-N	149917	US8975415, RP198::US9242973, RP198	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149917&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724315	252159445							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361968	NC1=NC2(c3cccc(F)c13)c1cc(ccc1OCC21CC1)-c1cncnc1	InChI=1S/C22H17FN4O/c23-17-3-1-2-15-19(17)20(24)27-22(15)16-8-13(14-9-25-12-26-10-14)4-5-18(16)28-11-21(22)6-7-21/h1-5,8-10,12H,6-7,11H2,(H2,24,27)	LEFCQXUNQUOKDG-UHFFFAOYSA-N	149918	US8975415, RP199::US9242973, RP199	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4250							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149918	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149918&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056126	252159446							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361969	NC1=NC2(CO1)c1cc(ccc1OC(Cc1ccccc1)C21COC1)-c1cncnc1	InChI=1S/C24H22N4O3/c25-22-28-24(14-30-22)19-9-17(18-10-26-15-27-11-18)6-7-20(19)31-21(23(24)12-29-13-23)8-16-4-2-1-3-5-16/h1-7,9-11,15,21H,8,12-14H2,(H2,25,28)	STMXAUVFLJMWDN-UHFFFAOYSA-N	149919	US8975415, RP200::US8975415, RP202::US9242973, RP202	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246750	252159447							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361970	NC1=NC2(CO1)c1cc(ccc1OC(Cc1ccccc1)C21COC1)-c1cncnc1	InChI=1S/C24H22N4O3/c25-22-28-24(14-30-22)19-9-17(18-10-26-15-27-11-18)6-7-20(19)31-21(23(24)12-29-13-23)8-16-4-2-1-3-5-16/h1-7,9-11,15,21H,8,12-14H2,(H2,25,28)	STMXAUVFLJMWDN-UHFFFAOYSA-N	149919	US8975415, RP200::US8975415, RP202::US9242973, RP202	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7730							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246750	252159447							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361971	NC1=NC2(CO1)c1cc(ccc1OC(CC1CC1)C21COC1)-c1cncnc1	InChI=1S/C21H22N4O3/c22-19-25-21(11-27-19)16-6-14(15-7-23-12-24-8-15)3-4-17(16)28-18(5-13-1-2-13)20(21)9-26-10-20/h3-4,6-8,12-13,18H,1-2,5,9-11H2,(H2,22,25)	MSVXPEWIJQOLDG-UHFFFAOYSA-N	149923	US8975415, RP204::US8975415, RP207::US9242973, RP207	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149923&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246751	252159449							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361972	CC#Cc1cncc(c1)-c1ccc2OC(CC3CC3)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C25H25N3O3/c1-2-3-17-8-19(12-27-11-17)18-6-7-21-20(10-18)25(15-30-23(26)28-25)24(13-29-14-24)22(31-21)9-16-4-5-16/h6-8,10-12,16,22H,4-5,9,13-15H2,1H3,(H2,26,28)	KJZOKUPYIWIFKS-UHFFFAOYSA-N	149924	US8975415, RP205::US9242973, RP205	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5220							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149924	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149924&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056128	252159450							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361973	NC1=NC2(c3cc(ccc3OCC22CC2)-c2cncnc2)C(F)(F)CO1	InChI=1S/C18H16F2N4O2/c19-17(20)9-26-15(21)24-18(17)13-5-11(12-6-22-10-23-7-12)1-2-14(13)25-8-16(18)3-4-16/h1-2,5-7,10H,3-4,8-9H2,(H2,21,24)	QZZCXMLMCPDROH-UHFFFAOYSA-N	149925	US8975415, RP206::US9242973, RP206	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149925&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056130	252159451							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361974	NC1=NC2(CO1)c1cc(ccc1OC(CC1CC1)C21COC1)-c1cncnc1	InChI=1S/C21H22N4O3/c22-19-25-21(11-27-19)16-6-14(15-7-23-12-24-8-15)3-4-17(16)28-18(5-13-1-2-13)20(21)9-26-10-20/h3-4,6-8,12-13,18H,1-2,5,9-11H2,(H2,22,25)	MSVXPEWIJQOLDG-UHFFFAOYSA-N	149923	US8975415, RP204::US8975415, RP207::US9242973, RP207	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149923&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246751	252159449							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361975	NC1=NC2(CO1)c1cc(ccc1OCC21CC(F)(F)C1)-c1cncnc1	InChI=1S/C18H16F2N4O2/c19-17(20)6-16(7-17)8-25-14-2-1-11(12-4-22-10-23-5-12)3-13(14)18(16)9-26-15(21)24-18/h1-5,10H,6-9H2,(H2,21,24)	IBQLKXDWVJSRDU-UHFFFAOYSA-N	149927	US8975415, RP208::US9242973, RP208	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149927&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056127	252159452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361976	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1	InChI=1S/C21H21N3O3/c22-18-24-21(13-26-18)16-9-14(15-3-1-8-23-10-15)4-5-17(16)27-20(6-2-7-20)19(21)11-25-12-19/h1,3-5,8-10H,2,6-7,11-13H2,(H2,22,24)	MJGALTWQDCBMQD-UHFFFAOYSA-N	149928	US8975415, RP209::US9242973, RP209	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056129	252159453							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361977	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cncc2ccccc12	InChI=1S/C25H23N3O3/c26-22-28-25(15-30-22)20-10-16(19-12-27-11-17-4-1-2-5-18(17)19)6-7-21(20)31-24(8-3-9-24)23(25)13-29-14-23/h1-2,4-7,10-12H,3,8-9,13-15H2,(H2,26,28)	NFVBGAGTKRCWGE-UHFFFAOYSA-N	149929	US8975415, RP210::US9242973, RP210	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3700							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149929&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90246752	252159454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361978	NC1=NC2(CO1)c1cc(ccc1OC1(CCC1)C21COC1)-c1cccnc1C(F)(F)F	InChI=1S/C22H20F3N3O3/c23-22(24,25)17-14(3-1-8-27-17)13-4-5-16-15(9-13)21(12-30-18(26)28-21)19(10-29-11-19)20(31-16)6-2-7-20/h1,3-5,8-9H,2,6-7,10-12H2,(H2,26,28)	XPOQBFAIFSUYIN-UHFFFAOYSA-N	149931	US8975415, RP212::US9242973, RP212	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149931&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056510	252159456							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361979	Cn1cc2cc(ccc2n1)-c1ccc2OCC3(CC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H20N4O2/c1-25-10-15-8-13(2-4-17(15)24-25)14-3-5-18-16(9-14)21(12-27-19(22)23-21)20(6-7-20)11-26-18/h2-5,8-10H,6-7,11-12H2,1H3,(H2,22,23)	LYIYOHNNHUSMFQ-UHFFFAOYSA-N	149932	US8975415, RP213::US9242973, RP213	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149932&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056496	252159457							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361980	NC1=NC2(COC1)c1cc(ccc1OCC21CC1)-c1cncnc1	InChI=1S/C18H18N4O2/c19-16-8-23-10-18(22-16)14-5-12(13-6-20-11-21-7-13)1-2-15(14)24-9-17(18)3-4-17/h1-2,5-7,11H,3-4,8-10H2,(H2,19,22)	AMQPJZMLPSZGED-UHFFFAOYSA-N	149934	US8975415, RP215::US9242973, RP215	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149934&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90025994	252159459							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361981	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@@]2(COC(N)=N2)C11COC1	InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	INWIVMOTHPFWNU-NRFANRHFSA-N	149936	US8975415, 218::US9242973, 218	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20670							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149936&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72202470	252159461							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361982	CC1(C)Oc2ccc(NC(=O)c3ccc(Br)cn3)cc2[C@@]2(COC(N)=N2)C11COC1	InChI=1S/C21H21BrN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	CWCLNAMDVBTHAU-NRFANRHFSA-N	149937	US8975415, 219::US9242973, 219	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149937&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90236720	252159462							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361983	COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(COC3)[C@]3(COC(N)=N3)c2c1	InChI=1S/C21H23N5O5/c1-19(2)20(9-29-10-20)21(11-30-18(22)26-21)13-6-12(4-5-15(13)31-19)25-17(27)14-7-24-16(28-3)8-23-14/h4-8H,9-11H2,1-3H3,(H2,22,26)(H,25,27)/t21-/m0/s1	WZWNQLAVZZUSHH-NRFANRHFSA-N	149938	US8975415, 220::US9242973, 220	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149938&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548948	252159463							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361984	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@@]2(COC(N)=N2)C11CC1	InChI=1S/C21H21ClN4O3/c1-19(2)20(7-8-20)21(11-28-18(23)26-21)14-9-13(4-6-16(14)29-19)25-17(27)15-5-3-12(22)10-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	SUARPGUFOBBSJS-NRFANRHFSA-N	149939	US8975415, 221::US9242973, 221	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3250							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056502	252159464							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361985	CC1(C)Oc2ccc(NC(=O)c3ccc(F)cn3)cc2[C@@]2(COC(N)=N2)C11CC1	InChI=1S/C21H21FN4O3/c1-19(2)20(7-8-20)21(11-28-18(23)26-21)14-9-13(4-6-16(14)29-19)25-17(27)15-5-3-12(22)10-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m0/s1	KFVQLLMGMYDUOM-NRFANRHFSA-N	149940	US8975415, 222::US9242973, 222	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149940	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149940&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90056497	252159465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361986	COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(CC3)[C@]3(COC(N)=N3)c2c1	InChI=1S/C21H23N5O4/c1-19(2)20(6-7-20)21(11-29-18(22)26-21)13-8-12(4-5-15(13)30-19)25-17(27)14-9-24-16(28-3)10-23-14/h4-5,8-10H,6-7,11H2,1-3H3,(H2,22,26)(H,25,27)/t21-/m0/s1	FVLGCKAZTKQUNT-NRFANRHFSA-N	149941	US8975415, 223::US9242973, 223	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20770							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724317	252159466							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361987	CC1(C)Oc2ccc(NC(=O)c3cnc(cn3)C(F)F)cc2[C@@]2(COC(N)=N2)C11CC1	InChI=1S/C21H21F2N5O3/c1-19(2)20(5-6-20)21(10-30-18(24)28-21)12-7-11(3-4-15(12)31-19)27-17(29)14-9-25-13(8-26-14)16(22)23/h3-4,7-9,16H,5-6,10H2,1-2H3,(H2,24,28)(H,27,29)/t21-/m0/s1	UUOAKQJQRFDOFS-NRFANRHFSA-N	149942	US8975415, 224::US9242973, 224	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15100							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149942&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724318	252159467							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361988	COc1cnc(cn1)C(=O)Nc1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1	InChI=1S/C21H23N5O5/c1-19(2)20(9-29-10-20)21(11-30-18(22)26-21)13-6-12(4-5-15(13)31-19)25-17(27)14-7-24-16(28-3)8-23-14/h4-8H,9-11H2,1-3H3,(H2,22,26)(H,25,27)	WZWNQLAVZZUSHH-UHFFFAOYSA-N	149943	US8975415, 227::US9242973, 227	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149943&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86724320	252159468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
361989	CC1(C)Oc2ccc(NC(=O)c3ccc(Cl)cn3)cc2[C@]2(COC(N)=N2)C11COC1	InChI=1S/C21H21ClN4O4/c1-19(2)20(9-28-10-20)21(11-29-18(23)26-21)14-7-13(4-6-16(14)30-19)25-17(27)15-5-3-12(22)8-24-15/h3-8H,9-11H2,1-2H3,(H2,23,26)(H,25,27)/t21-/m1/s1	INWIVMOTHPFWNU-OAQYLSRUSA-N	149944	US8975415, 228a::US9242973, 228a	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q29W0D9C		aid1802183	US9242973	Munakata, R; Inoue, M; Tominaga, H; Yamasaki, S; Shiina, Y; Samizu, K; Hamaguchi, H; Hong, L	1/26/2016	12/5/2016	CoMentis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=149944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=149944&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72548947	252159469							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
386847	CN(C)CCN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(o1)-c1ccncc1)C(F)(F)F	InChI=1S/C25H28F3N5O2/c1-31(2)11-12-32-13-15-33(16-14-32)21-4-3-19(25(26,27)28)17-20(21)30-24(34)23-6-5-22(35-23)18-7-9-29-10-8-18/h3-10,17H,11-16H2,1-2H3,(H,30,34)	ALLIMXLDTJFWHR-UHFFFAOYSA-N	221073	SPHINX scaffold, 3::US9695160, SPHINX7::US9796707, Reference Compound SPHINX7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 36					7.45	37.00 C	Curated from the literature by BindingDB	10.1021/acschembio.6b01048	10.7270/Q2K64GXC	28135068	aid1802549		Batson, J; Toop, HD; Redondo, C; Babaei-Jadidi, R; Chaikuad, A; Wearmouth, SF; Gibbons, B; Allen, C; Tallant, C; Zhang, J; Du, C; Hancox, JC; Hawtrey, T; Da Rocha, J; Griffith, R; Knapp, S; Bates, DO; Morris, JC	3/17/2017	4/6/2017	Exonate Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221073&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			73672854	335960148							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
386848	FC(F)(F)c1ccc(N2CCN(Cc3ccccn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1	InChI=1S/C27H24F3N5O2/c28-27(29,30)20-4-5-23(35-15-13-34(14-16-35)18-21-3-1-2-10-32-21)22(17-20)33-26(36)25-7-6-24(37-25)19-8-11-31-12-9-19/h1-12,17H,13-16,18H2,(H,33,36)	VURLRACCOCGFDB-UHFFFAOYSA-N	221074	SPHINX31::US9695160, 12::US9796707, Compound 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 300					7.45	37.00 C	Curated from the literature by BindingDB	10.1021/acschembio.6b01048	10.7270/Q2K64GXC	28135068	aid1802549		Batson, J; Toop, HD; Redondo, C; Babaei-Jadidi, R; Chaikuad, A; Wearmouth, SF; Gibbons, B; Allen, C; Tallant, C; Zhang, J; Du, C; Hancox, JC; Hawtrey, T; Da Rocha, J; Griffith, R; Knapp, S; Bates, DO; Morris, JC	3/17/2017	4/6/2017	Exonate Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221074&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	RXZ	5MY8	91972002	335960149							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
388343	NCCCCN(Cc1nccc2c3ccccc3n(CC(O)=O)c12)[C@H]1CCCc2cccnc12	InChI=1S/C27H31N5O2/c28-13-3-4-16-31(24-11-5-7-19-8-6-14-30-26(19)24)17-22-27-21(12-15-29-22)20-9-1-2-10-23(20)32(27)18-25(33)34/h1-2,6,8-10,12,14-15,24H,3-5,7,11,13,16-18,28H2,(H,33,34)/t24-/m0/s1	HXSKVZXRXQFNGG-DEOSSOPVSA-N	221769	US9314468, Table 7, Compound 56::US9314468, Table 9, Compound 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700						25.00 C	US Patent		10.7270/Q2DF6Q2P		aid1802565	US9314468	Clark, MP; Wagner, FF; Natchus, MG; Doroh, BC; Johnson, TL; Tahirovic, YA; Wilson, L; Wiseman, JM; Skudlarek, JW; Lockwood, MA	4/19/2016	4/10/2017	Altiris Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221769&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			59176365	335960702							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
388344	NCCCCN(Cc1nccc2c3ccccc3n(CCCN3CCNCC3)c12)[C@H]1CCCc2cccnc12	InChI=1S/C32H43N7/c33-14-3-4-20-38(30-12-5-8-25-9-6-15-36-31(25)30)24-28-32-27(13-16-35-28)26-10-1-2-11-29(26)39(32)21-7-19-37-22-17-34-18-23-37/h1-2,6,9-11,13,15-16,30,34H,3-5,7-8,12,14,17-24,33H2/t30-/m0/s1	KRDNCRHWZIFVKV-PMERELPUSA-N	221783	US9314468, Table 7, Compound 70::US9314468, Table 9, Compound 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100						25.00 C	US Patent		10.7270/Q2DF6Q2P		aid1802565	US9314468	Clark, MP; Wagner, FF; Natchus, MG; Doroh, BC; Johnson, TL; Tahirovic, YA; Wilson, L; Wiseman, JM; Skudlarek, JW; Lockwood, MA	4/19/2016	4/10/2017	Altiris Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221783	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221783&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			59176504	335960710							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
388345	C(CN(Cc1nccc2c3ccccc3n(CCN3CCOCC3)c12)C1CCCc2cccnc12)CN1CCNCC1	InChI=1S/C34H45N7O/c1-2-9-31-28(8-1)29-11-13-36-30(34(29)41(31)21-20-39-22-24-42-25-23-39)26-40(17-5-16-38-18-14-35-15-19-38)32-10-3-6-27-7-4-12-37-33(27)32/h1-2,4,7-9,11-13,32,35H,3,5-6,10,14-26H2	GXPPYEGXOSWLLT-UHFFFAOYSA-N	221871	US9314468, Table 8, Compound 9::US9314468, Table 9, Compound 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3100						25.00 C	US Patent		10.7270/Q2DF6Q2P		aid1802565	US9314468	Clark, MP; Wagner, FF; Natchus, MG; Doroh, BC; Johnson, TL; Tahirovic, YA; Wilson, L; Wiseman, JM; Skudlarek, JW; Lockwood, MA	4/19/2016	4/10/2017	Altiris Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70965023	335960785							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
388346	OCCn1c2ccccc2c2ccnc(CN(CCCN3CCNCC3)C3CCCc4cccnc34)c12	InChI=1S/C30H38N6O/c37-21-20-36-27-9-2-1-8-24(27)25-11-13-32-26(30(25)36)22-35(17-5-16-34-18-14-31-15-19-34)28-10-3-6-23-7-4-12-33-29(23)28/h1-2,4,7-9,11-13,28,31,37H,3,5-6,10,14-22H2	PLCLLBVMKOLHCX-UHFFFAOYSA-N	221876	US9314468, Table 8, Compound 14::US9314468, Table 9, Compound 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2400						25.00 C	US Patent		10.7270/Q2DF6Q2P		aid1802565	US9314468	Clark, MP; Wagner, FF; Natchus, MG; Doroh, BC; Johnson, TL; Tahirovic, YA; Wilson, L; Wiseman, JM; Skudlarek, JW; Lockwood, MA	4/19/2016	4/10/2017	Altiris Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			72535480	335960790							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
388347	NCCCCN(Cc1nccc2c3ccccc3n(CC(N)=O)c12)[C@H]1CCCc2cccnc12	InChI=1S/C27H32N6O/c28-13-3-4-16-32(24-11-5-7-19-8-6-14-31-26(19)24)17-22-27-21(12-15-30-22)20-9-1-2-10-23(20)33(27)18-25(29)34/h1-2,6,8-10,12,14-15,24H,3-5,7,11,13,16-18,28H2,(H2,29,34)/t24-/m0/s1	ABDLOXDCMBBRCJ-DEOSSOPVSA-N	221825	US9314468, Table 7, Compound 112::US9314468, Table 9, Compound 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1800						25.00 C	US Patent		10.7270/Q2DF6Q2P		aid1802565	US9314468	Clark, MP; Wagner, FF; Natchus, MG; Doroh, BC; Johnson, TL; Tahirovic, YA; Wilson, L; Wiseman, JM; Skudlarek, JW; Lockwood, MA	4/19/2016	4/10/2017	Altiris Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221825&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			59176416	335960744							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
390525	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2ccc(OC(F)F)cn2)cs1	InChI=1S/C18H19F2N5O3S2/c1-9-4-10-6-30-17(21)25-18(10,8-27-9)15-24-13(7-29-15)23-14(26)12-3-2-11(5-22-12)28-16(19)20/h2-3,5,7,9-10,16H,4,6,8H2,1H3,(H2,21,25)(H,23,26)/t9-,10-,18-/m0/s1	ZLZUHACSRMOLLV-RAALSFIWSA-N	223395	US9315520, 1::US9315520, Comparator 1::US9315520, Example 1::US9315520, Example 2::US9605007, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9900						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223395&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435360	336285270							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
390526	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2ccc(OC(F)F)cn2)cs1	InChI=1S/C18H19F2N5O3S2/c1-9-4-10-6-30-17(21)25-18(10,8-27-9)15-24-13(7-29-15)23-14(26)12-3-2-11(5-22-12)28-16(19)20/h2-3,5,7,9-10,16H,4,6,8H2,1H3,(H2,21,25)(H,23,26)/t9-,10-,18-/m0/s1	ZLZUHACSRMOLLV-RAALSFIWSA-N	223395	US9315520, 1::US9315520, Comparator 1::US9315520, Example 1::US9315520, Example 2::US9605007, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23600						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223395&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435360	336285270							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
390527	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2ccc(Cl)cn2)cs1	InChI=1S/C17H18ClN5O2S2/c1-9-4-10-6-27-16(19)23-17(10,8-25-9)15-22-13(7-26-15)21-14(24)12-3-2-11(18)5-20-12/h2-3,5,7,9-10H,4,6,8H2,1H3,(H2,19,23)(H,21,24)/t9-,10-,17-/m0/s1	UFKMIVRYLMOXNT-YMNVWFMLSA-N	223396	US9315520, 7::US9315520, Example 7::US9605007, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9000						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223396&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435407	336285271							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
390528	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2ncc(OC(F)F)cc2C)cs1	InChI=1S/C19H21F2N5O3S2/c1-9-3-12(29-17(20)21)5-23-14(9)15(27)24-13-7-30-16(25-13)19-8-28-10(2)4-11(19)6-31-18(22)26-19/h3,5,7,10-11,17H,4,6,8H2,1-2H3,(H2,22,26)(H,24,27)/t10-,11-,19-/m0/s1	CHAGAOAUIITKPC-ADWYPQAOSA-N	223400	US9315520, 45::US9315520, Example 45::US9605007, Example 45::US9744173, Example 45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9600						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223400&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435524	336285273							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
390529	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2ccc(OC(F)F)cn2)ccc1F	InChI=1S/C20H20F3N5O3S/c1-10-6-11-8-32-19(24)28-20(11,9-30-10)16-13(21)3-5-15(26-16)27-17(29)14-4-2-12(7-25-14)31-18(22)23/h2-5,7,10-11,18H,6,8-9H2,1H3,(H2,24,28)(H,26,27,29)/t10-,11-,20-/m0/s1	NCLSCERPSPVBHT-MKXJDEKUSA-N	223398	US9315520, Comparator 2::US9315520, Comparator 3::US9605007, Comparator 2::US9744173, Comparator 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 400						37.00 C	US Patent		10.7270/Q20000Z5		aid1802665	US9315520	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O&#39;Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	4/19/2016	5/1/2017	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223398&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118441558	336285272							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
413064	CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H]1[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](C[C@H]2CNC(=N)N2)NC(=O)[C@H](C)NC1=O)[C@@H](C)CC	InChI=1S/C58H95N15O15/c1-12-28(5)42(70-49(79)37(61-11)23-34-19-17-16-18-20-34)53(83)67-39(26-74)51(81)65-36(21-22-41(59)76)48(78)69-44(30(7)14-3)55(85)71-43(29(6)13-2)54(84)68-40(27-75)52(82)73-46-33(10)88-57(87)45(31(8)15-4)72-50(80)38(24-35-25-62-58(60)64-35)66-47(77)32(9)63-56(46)86/h16-20,28-33,35-40,42-46,61,74-75H,12-15,21-27H2,1-11H3,(H2,59,76)(H,63,86)(H,65,81)(H,66,77)(H,67,83)(H,68,84)(H,69,78)(H,70,79)(H,71,85)(H,72,80)(H,73,82)(H3,60,62,64)/t28-,29-,30-,31-,32-,33-,35-,36+,37+,38-,39-,40-,42-,43-,44+,45-,46+/m0/s1	LMBFAGIMSUYTBN-MPZNNTNKSA-N	237161	US9402878, II	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1.00e+5					7		US Patent		10.7270/Q2J67FTF		aid1803122	US9402878	Peoples, AJ; Hughes, D; Ling, LL; Millett, W; Nitti, A; Spoering, A; Steadman, VA; Chiva, JC; Lazarides, L; Jones, MK; Poullennec, KG; Lewis, K; Epstein, S	8/2/2016	7/10/2017	NovoBiotic Pharmaceuticals, LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237161&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86341926	340130728							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
413065	COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1	InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-/m0/s1	LOUPRKONTZGTKE-LHHVKLHASA-N	50121975	(6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol::CARDIOQUIN::CHEMBL1294::CIN-QUIN::DURAQUIN::QUINACT::QUINAGLUTE::QUINALAN::QUINATIME::QUINIDEX::QUINIDINE::QUINORA::US9402878, Quinidine	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.44e+3					7		US Patent		10.7270/Q2J67FTF		aid1803122	US9402878	Peoples, AJ; Hughes, D; Ling, LL; Millett, W; Nitti, A; Spoering, A; Steadman, VA; Chiva, JC; Lazarides, L; Jones, MK; Poullennec, KG; Lewis, K; Epstein, S	8/2/2016	7/10/2017	NovoBiotic Pharmaceuticals, LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121975&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	QDN	6LQA,4WNU	441074	104014718	28593	CHEMBL1294	DB00908	2342	C06527	ZINC03831405	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422698	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1	InChI=1S/C21H25ClN4O/c1-21(2,27)15-6-8-17(9-7-15)24-19-10-11-20-23-13-18(26(20)25-19)14-4-3-5-16(22)12-14/h3-5,10-13,15,17,27H,6-9H2,1-2H3,(H,24,25)/t15-,17-	BZNALBIJBHYZPW-JCNLHEQBSA-N	242380	US10047093, 8-37::US10392392, Example 8-37::US10875864, EX. 8-37::US9416132, 8-37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242380&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598035	341094631							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422699	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1	InChI=1S/C18H19ClN4O/c19-13-3-1-2-12(10-13)16-11-20-18-9-8-17(22-23(16)18)21-14-4-6-15(24)7-5-14/h1-3,8-11,14-15,24H,4-7H2,(H,21,22)/t14-,15-	OKAUIWRBORRFHW-SHTZXODSSA-N	242378	US10047093, 8-35::US10392392, Example 8-35::US10875864, EX. 8-35::US9416132, 8-35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242378&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598229	341094629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422700	CO[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1	InChI=1S/C19H21ClN4O/c1-25-16-7-5-15(6-8-16)22-18-9-10-24-19(23-18)17(12-21-24)13-3-2-4-14(20)11-13/h2-4,9-12,15-16H,5-8H2,1H3,(H,22,23)/t15-,16-	FBQBEGGSOHQPPV-WKILWMFISA-N	242409	US9416132, 8-64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242409&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66615214	341094659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422701	Clc1cccc(c1)-c1cnc2ccc(NC3CCOCC3)nn12	InChI=1S/C17H17ClN4O/c18-13-3-1-2-12(10-13)15-11-19-17-5-4-16(21-22(15)17)20-14-6-8-23-9-7-14/h1-5,10-11,14H,6-9H2,(H,20,21)	OEIWNDGDGDPXIO-UHFFFAOYSA-N	35052	K00152::US10047093, 8-39::US10392392, Example 8-39::US10875864, EX. 8-39::US9416132, 8-39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			6419807	85753134						ZINC28530942	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422702	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1	InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)/t15-,17-	XRNVABDYQLHODA-JCNLHEQBSA-N	242374	US10047093, 8-31::US10392392, Example 8-31::US10875864, EX. 8-31::US9416132, 8-31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242374&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598080	341094625							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422703	C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1	InChI=1S/C20H21F3N4O/c1-19(28)9-7-15(8-10-19)25-17-5-6-18-24-12-16(27(18)26-17)13-3-2-4-14(11-13)20(21,22)23/h2-6,11-12,15,28H,7-10H2,1H3,(H,25,26)/t15-,19-	SZDYHSAHSPZDEB-RHDGDCLCSA-N	242373	US10047093, 8-30::US10392392, Example 8-30::US10875864, EX. 8-30::US9416132, 8-30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242373&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598034	341094624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422704	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1	InChI=1S/C19H19F3N4O/c20-19(21,22)13-3-1-2-12(10-13)16-11-23-18-9-8-17(25-26(16)18)24-14-4-6-15(27)7-5-14/h1-3,8-11,14-15,27H,4-7H2,(H,24,25)/t14-,15-	OIWKVZIBVNRNOJ-SHTZXODSSA-N	242372	US10047093, 8-29::US10392392, Example 8-29::US10875864, EX. 8-29::US9416132, 8-29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242372&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598158	341094623							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422705	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C22H25F3N4O2/c1-21(2,30)15-6-8-16(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-17(12-14)31-22(23,24)25/h3-5,10-13,15-16,30H,6-9H2,1-2H3,(H,27,28)/t15-,16-	NMIBDYYYDQCKBY-WKILWMFISA-N	242354	US10047093, 8-10::US10392392, Example 8-10::US10875864, EX. 8-10::US9416132, 8-10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242354&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597963	341094605							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422706	C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C20H21F3N4O2/c1-19(28)9-7-14(8-10-19)25-17-5-6-18-24-12-16(27(18)26-17)13-3-2-4-15(11-13)29-20(21,22)23/h2-6,11-12,14,28H,7-10H2,1H3,(H,25,26)/t14-,19-	YVGAENJCKBRBJB-QUWSVYMGSA-N	242353	US10047093, 8-9::US10392392, Example 8-9::US10875864, EX. 8-9::US9416132, 8-9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242353&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597961	341094604							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422707	CO[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C20H21F3N4O2/c1-28-15-7-5-14(6-8-15)25-18-9-10-19-24-12-17(27(19)26-18)13-3-2-4-16(11-13)29-20(21,22)23/h2-4,9-12,14-15H,5-8H2,1H3,(H,25,26)/t14-,15-	DFNCXHFRDZBFKJ-SHTZXODSSA-N	242355	US9416132, 8-11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242355&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66615217	341094606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422708	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1	InChI=1S/C21H25ClN4O/c1-21(2,27)15-6-8-17(9-7-15)24-19-10-11-26-20(25-19)18(13-23-26)14-4-3-5-16(22)12-14/h3-5,10-13,15,17,27H,6-9H2,1-2H3,(H,24,25)/t15-,17-	QWEBKNRGVXJIKS-JCNLHEQBSA-N	50043697	CHEMBL3355987::US10047093, 8-63::US10392392, Example 8-63::US10875864, EX. 8-63::US9416132, 8-63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043697&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597997	103975081		CHEMBL3355987				ZINC13733479	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422709	O[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1	InChI=1S/C19H19F3N4O/c20-19(21,22)13-3-1-2-12(10-13)16-11-23-26-9-8-17(25-18(16)26)24-14-4-6-15(27)7-5-14/h1-3,8-11,14-15,27H,4-7H2,(H,24,25)/t14-,15-	DFHQXRLKAFZKPB-SHTZXODSSA-N	50043674	CHEMBL3355550::US10047093, 8-54::US10392392, Example 8-54::US10875864, EX. 8-54::US9416132, 8-54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043674&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598095	103975058		CHEMBL3355550				ZINC13896112	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422710	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1	InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-29-20(28-19)18(13-26-29)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)/t15-,17-	FSQNGXYJUMATLF-JCNLHEQBSA-N	50043662	CHEMBL3355552::US10047093, 8-56::US10392392, Example 8-56::US10875864, EX. 8-56::US9416132, 8-56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043662&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598153	103975046		CHEMBL3355552					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422711	O[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(OC(F)(F)F)c3)c2n1	InChI=1S/C19H19F3N4O2/c20-19(21,22)28-15-3-1-2-12(10-15)16-11-23-26-9-8-17(25-18(16)26)24-13-4-6-14(27)7-5-13/h1-3,8-11,13-14,27H,4-7H2,(H,24,25)/t13-,14-	ATMAGFPFVYJWHA-HDJSIYSDSA-N	50043690	CHEMBL3355544::US10047093, 8-46::US10392392, Example 8-46::US10875864, EX. 8-46::US9416132, 8-46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043690&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597981	103975074		CHEMBL3355544				ZINC13733469	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422712	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C19H19F3N4O2/c20-19(21,22)28-15-3-1-2-12(10-15)16-11-23-18-9-8-17(25-26(16)18)24-13-4-6-14(27)7-5-13/h1-3,8-11,13-14,27H,4-7H2,(H,24,25)/t13-,14-	LOMZUAFMSBAHAU-HDJSIYSDSA-N	242345	US10047093, 8-1::US10392392, Example 8-1::US10875864, EX. 8-1::US9416132, 8-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242345&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24996072	341094596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
422713	FC(F)(F)Oc1cccc(c1)-c1cnc2ccc(NCC3CCS(=O)(=O)CC3)nn12	InChI=1S/C19H19F3N4O3S/c20-19(21,22)29-15-3-1-2-14(10-15)16-12-24-18-5-4-17(25-26(16)18)23-11-13-6-8-30(27,28)9-7-13/h1-5,10,12-13H,6-9,11H2,(H,23,25)	JABDFUFLQGAQCU-UHFFFAOYSA-N	242356	US10047093, 8-13::US10392392, Example 8-13::US10875864, EX. 8-13::US9416132, 8-13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q2CV4GNG		aid1803302	US9416132	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, M; Ho, K	8/16/2016	8/14/2017	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242356&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598170	341094607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423432	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(Cl)c(Cl)c1	InChI=1S/C16H14Cl2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-11(17)12(18)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	ZMVUVIKWZWFBIB-MRVPVSSYSA-N	242740	US10030025, Compound 1::US10836768, Cpd no 1::US9422299, 1::US9987274, Compound 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 42000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242740&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274487	341094880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423433	CCc1nsc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6OS/c1-3-13-19-16(26-22-13)15-21-20-14-10(2)23(8-9-24(14)15)17(25)11-4-6-12(18)7-5-11/h4-7,10H,3,8-9H2,1-2H3/t10-/m1/s1	UOMUYZXEONWAOD-SNVBAGLBSA-N	242741	US10030025, Compound 2::US10836768, Cpd no 2::US9422299, 2::US9987274, Compound 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242741&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274488	341094881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423434	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(Cl)cc1	InChI=1S/C16H15ClN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1	ZMIOQWILBZBCHW-SECBINFHSA-N	50112181	CHEMBL3608687::US10030025, Compound 3::US10836768, Cpd no 3::US9422299, 3::US9987274, Compound 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 66000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112181&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274489	319493540		CHEMBL3608687					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423435	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(Cl)c(F)c1	InChI=1S/C16H14ClFN6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-11(17)12(18)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	WVMPHKVLGBDWHJ-MRVPVSSYSA-N	242742	US10030025, Compound 4::US10836768, Cpd no 4::US9422299, 4::US9987274, Compound 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242742&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274490	341094882							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423436	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1	InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1	PPSNFPASKFYPMN-SECBINFHSA-N	50112244	CHEMBL3608680::US10030025, Compound 5::US10836768, Cpd no 5::US9422299, 5::US9987274, Compound 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112244&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117604931	104006697		CHEMBL3608680				ZINC29554298	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423437	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(Cl)c1	InChI=1S/C16H14ClFN6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-12(18)11(17)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	DMCGPNZWXATPEH-MRVPVSSYSA-N	242743	US10030025, Compound 6::US10836768, Cpd no 6::US9422299, 6::US9987274, Compound 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 45000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242743&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274727	341094883							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423438	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cc(F)c(F)c(F)c1	InChI=1S/C16H13F3N6OS/c1-7-13-21-22-14(15-20-8(2)23-27-15)25(13)4-3-24(7)16(26)9-5-10(17)12(19)11(18)6-9/h5-7H,3-4H2,1-2H3/t7-/m1/s1	UFMPQBXIACFWKA-SSDOTTSWSA-N	242744	US10030025, Compound 7::US10836768, Cpd no 7::US9422299, 7::US9987274, Compound 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242744&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274728	341094884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423439	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(F)c1F	InChI=1S/C16H13F3N6OS/c1-7-13-21-22-14(15-20-8(2)23-27-15)25(13)6-5-24(7)16(26)9-3-4-10(17)12(19)11(9)18/h3-4,7H,5-6H2,1-2H3/t7-/m1/s1	VKDRGGCFNJISDJ-SSDOTTSWSA-N	242745	US10030025, Compound 8::US10836768, Cpd no 8::US9422299, 8::US9987274, Compound 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242745&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274729	341094885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423440	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(F)c1	InChI=1S/C16H14F2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-11(17)12(18)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	VRVGLEWHAKZMDU-MRVPVSSYSA-N	242746	US10030025, Compound 9::US10836768, Cpd no 9::US9422299, 9::US9987274, Compound 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242746&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274730	341094886							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423441	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cc(F)c(F)c(F)c1F	InChI=1S/C16H12F4N6OS/c1-6-13-22-23-14(15-21-7(2)24-28-15)26(13)4-3-25(6)16(27)8-5-9(17)11(19)12(20)10(8)18/h5-6H,3-4H2,1-2H3/t6-/m1/s1	OWGILKMONFDDTK-ZCFIWIBFSA-N	242747	US10030025, Compound 10::US10836768, Cpd no 10::US9422299, 10::US9987274, Compound 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242747&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274731	341094887							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423442	Cc1nsc(n1)-c1nnc2[C@@H](CCO)N(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6O2S/c1-10-19-16(27-22-10)15-21-20-14-13(6-9-25)23(7-8-24(14)15)17(26)11-2-4-12(18)5-3-11/h2-5,13,25H,6-9H2,1H3/t13-/m1/s1	SZEYAOKHLPDWFZ-CYBMUJFWSA-N	50112245	CHEMBL3608741::US10030025, Compound 11::US10836768, Cpd no 11::US9422299, 11::US9987274, Compound 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 50000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112245&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274732	104006698		CHEMBL3608741				ZINC29556794	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423443	CCc1noc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6O2/c1-3-13-19-16(26-22-13)15-21-20-14-10(2)23(8-9-24(14)15)17(25)11-4-6-12(18)7-5-11/h4-7,10H,3,8-9H2,1-2H3/t10-/m1/s1	AWKTWOOCLJMRQH-SNVBAGLBSA-N	242749	US10030025, Compound 13::US10836768, Cpd no 13::US9422299, 13::US9987274, Compound 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242749&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274961	341094889							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423444	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cccc(F)c1	InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)7-6-22(9)16(24)11-4-3-5-12(17)8-11/h3-5,8-9H,6-7H2,1-2H3/t9-/m1/s1	ROHADLHITYWLQW-SECBINFHSA-N	242751	US10030025, Compound 15::US10836768, Cpd no 15::US9422299, 15::US9987274, Compound 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274963	341094891							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423445	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cccc(Cl)c1	InChI=1S/C16H15ClN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)7-6-22(9)16(24)11-4-3-5-12(17)8-11/h3-5,8-9H,6-7H2,1-2H3/t9-/m1/s1	LQGKKZYSNBYZNR-SECBINFHSA-N	242752	US10030025, Compound 16::US10836768, Cpd no 16::US9422299, 16::US9987274, Compound 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274964	341094892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423446	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cc(F)cc(F)c1	InChI=1S/C16H14F2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)4-3-23(8)16(25)10-5-11(17)7-12(18)6-10/h5-8H,3-4H2,1-2H3/t8-/m1/s1	IQKKFYUURGEICP-MRVPVSSYSA-N	242753	US10030025, Compound 17::US10836768, Cpd no 17::US9422299, 17::US9987274, Compound 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242753&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274965	341094893							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423447	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1F	InChI=1S/C16H14F2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)11-4-3-10(17)7-12(11)18/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	OZEMPZBRQPJERB-MRVPVSSYSA-N	242754	US10030025, Compound 18::US10836768, Cpd no 18::US9422299, 18::US9987274, Compound 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242754&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274966	341094894							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423448	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccccc1	InChI=1S/C16H16N6OS/c1-10-13-18-19-14(15-17-11(2)20-24-15)22(13)9-8-21(10)16(23)12-6-4-3-5-7-12/h3-7,10H,8-9H2,1-2H3/t10-/m1/s1	HQFWWFCJWZXHFM-SNVBAGLBSA-N	50112179	CHEMBL3608740::US10030025, Compound 20::US10836768, Cpd no 20::US9422299, 20::US9987274, Compound 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 50000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112179&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275207	319493538		CHEMBL3608740					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423449	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(cc1)C(F)(F)F	InChI=1S/C17H15F3N6OS/c1-9-13-22-23-14(15-21-10(2)24-28-15)26(13)8-7-25(9)16(27)11-3-5-12(6-4-11)17(18,19)20/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1	MJAOQGKUYGSDSK-SECBINFHSA-N	242756	US10030025, Compound 21::US10836768, Cpd no 21::US9422299, 21::US9987274, Compound 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 45000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242756	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242756&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275208	341094896							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423450	CC[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6OS/c1-3-13-14-20-21-15(16-19-10(2)22-26-16)24(14)9-8-23(13)17(25)11-4-6-12(18)7-5-11/h4-7,13H,3,8-9H2,1-2H3/t13-/m1/s1	OZKSTTVUQRWBIO-CYBMUJFWSA-N	242757	US10030025, Compound 22::US10836768, Cpd no 22::US9422299, 22::US9987274, Compound 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242757&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275209	341094897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423451	CCC[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1	InChI=1S/C18H19FN6OS/c1-3-4-14-15-21-22-16(17-20-11(2)23-27-17)25(15)10-9-24(14)18(26)12-5-7-13(19)8-6-12/h5-8,14H,3-4,9-10H2,1-2H3/t14-/m1/s1	GEUWDXLPGYKMAG-CQSZACIVSA-N	242759	US10030025, Compound 24::US10836768, Cpd no 24::US9422299, 24::US9987274, Compound 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 61000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275211	341094899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423452	COc1cccc(c1)C(=O)N1CCn2c(nnc2-c2nc(C)ns2)[C@H]1C	InChI=1S/C17H18N6O2S/c1-10-14-19-20-15(16-18-11(2)21-26-16)23(14)8-7-22(10)17(24)12-5-4-6-13(9-12)25-3/h4-6,9-10H,7-8H2,1-3H3/t10-/m1/s1	YKIGSSIUJRGFEY-SNVBAGLBSA-N	242762	US10030025, Compound 27::US9422299, 27::US9987274, Compound 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242762	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242762&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275448	341094902							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423453	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(cc1)C#N	InChI=1S/C17H15N7OS/c1-10-14-20-21-15(16-19-11(2)22-26-16)24(14)8-7-23(10)17(25)13-5-3-12(9-18)4-6-13/h3-6,10H,7-8H2,1-2H3/t10-/m1/s1	BYTHHHFQHHITDO-SNVBAGLBSA-N	242763	US10836768, Cpd no 29::US9422299, 29::US9987274, Compound 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 59000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242763	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242763&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275450	341094903							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
423454	CCc1noc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C21H20N6O2S/c1-3-17-22-20(29-25-17)19-24-23-18-13(2)26(10-11-27(18)19)21(28)15-8-6-14(7-9-15)16-5-4-12-30-16/h4-9,12-13H,3,10-11H2,1-2H3/t13-/m1/s1	DOEVSBYTUDFXBA-CYBMUJFWSA-N	242764	US10030025, Compound 30::US10836768, Cpd no 30::US9422299, 30::US9987274, Compound 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32000							US Patent		10.7270/Q2GM866C		aid1803315	US9422299	Hoveyda, H; Dutheuil, G; Fraser, G	8/23/2016	8/14/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242764	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242764&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275451	341094904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
432919	Oc1cc(Cl)c2c(c[nH]c2c1)C(=O)OCC12CCN(CC1)CC2	InChI=1S/C17H19ClN2O3/c18-13-7-11(21)8-14-15(13)12(9-19-14)16(22)23-10-17-1-4-20(5-2-17)6-3-17/h7-9,19,21H,1-6,10H2	ZZNMCYCBKMJHPV-UHFFFAOYSA-N	247990	US9434724, 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000					7.4		US Patent		10.7270/Q2M32TPW		aid1803407	US9434724	Bilcer, GM; Ng, R	9/6/2016	9/5/2017	ALPHARMAGEN, LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247990&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118644558	346542522							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
432920	Cc1cc(Cl)c2c(c[nH]c2c1)C(=O)OCC12CCN(CC1)CC2	InChI=1S/C18H21ClN2O2/c1-12-8-14(19)16-13(10-20-15(16)9-12)17(22)23-11-18-2-5-21(6-3-18)7-4-18/h8-10,20H,2-7,11H2,1H3	DCZGNMUEAXUIHE-UHFFFAOYSA-N	247994	US9434724, 65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2430					7.4		US Patent		10.7270/Q2M32TPW		aid1803407	US9434724	Bilcer, GM; Ng, R	9/6/2016	9/5/2017	ALPHARMAGEN, LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118644646	346542526							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
438647	CS(=O)(=O)C1(CCOCC1)c1nc(nc2N3CCOC[C@H]3COc12)-c1cccc2[nH]ccc12			251580	US9453031, 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6000000							US Patent		10.7270/Q27H1HH8		aid1803505	US9453031	Pastor Fernandez, J; Fernandez-Capetillo Ruiz, O; Martinez Gonzalez, S; Blanco Aparicio, C; Rico Ferreira, M; Toledo Lazaro, LI; Rodriguez Aristegui, S; Murga Costa, M; Varela Busto, C; Lopez Contreras, AJ; Renner, O; Nieto Soler, M; Cebrian Munoz, DA	9/27/2016	9/25/2017	Fundaci&#243;n Centro Nacional de Investigaciones Oncol&#243;gicas Carlos III	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251580&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			78210287	346546031							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
438648	CNc1nc2ccccc2n1-c1nc2N3CCOC[C@H]3COc2c(n1)C(C)(C)S(C)(=O)=O	InChI=1S/C21H26N6O4S/c1-21(2,32(4,28)29)17-16-18(26-9-10-30-11-13(26)12-31-16)25-20(24-17)27-15-8-6-5-7-14(15)23-19(27)22-3/h5-8,13H,9-12H2,1-4H3,(H,22,23)/t13-/m0/s1	JEWXHIMACGOZFL-ZDUSSCGKSA-N	251588	US9453031, 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4000000							US Patent		10.7270/Q27H1HH8		aid1803505	US9453031	Pastor Fernandez, J; Fernandez-Capetillo Ruiz, O; Martinez Gonzalez, S; Blanco Aparicio, C; Rico Ferreira, M; Toledo Lazaro, LI; Rodriguez Aristegui, S; Murga Costa, M; Varela Busto, C; Lopez Contreras, AJ; Renner, O; Nieto Soler, M; Cebrian Munoz, DA	9/27/2016	9/25/2017	Fundaci&#243;n Centro Nacional de Investigaciones Oncol&#243;gicas Carlos III	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86268192	346546039							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
438923	CN1[C@@H](C2=C(CCC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1CO)C#N	InChI=1S/C23H18F3N3O3/c1-28-21(17-6-5-13(11-27)9-14(17)12-30)20-18(7-8-19(20)31)29(22(28)32)16-4-2-3-15(10-16)23(24,25)26/h2-6,9-10,21,30H,7-8,12H2,1H3/t21-/m1/s1	RTKSIJXCPYPYCH-OAQYLSRUSA-N	251855	US9475779, A.1A	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2QJ7G77		aid1803512	US9475779	Oost, T; Anderskewitz, R; Gnamm, C; Hoesch, H; Morschhaeuser, G; Peters, S; Ries, UJ	10/25/2016	9/25/2017	Boehringer Ingelheim International GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251855&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			131635857	346546304							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
438924	CN1[C@H](C2=C(CCC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1S(=O)(=O)CCO)C#N	InChI=1S/C24H20F3N3O5S/c1-29-22(17-6-5-14(13-28)11-20(17)36(34,35)10-9-31)21-18(7-8-19(21)32)30(23(29)33)16-4-2-3-15(12-16)24(25,26)27/h2-6,11-12,22,31H,7-10H2,1H3/t22-/m0/s1	VJZWSSKZHHSBEL-QFIPXVFZSA-N	251826	US9475779, B.1.2B	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2QJ7G77		aid1803512	US9475779	Oost, T; Anderskewitz, R; Gnamm, C; Hoesch, H; Morschhaeuser, G; Peters, S; Ries, UJ	10/25/2016	9/25/2017	Boehringer Ingelheim International GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251826&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			131635854	346546275							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
438925	CN1[C@@H](C2=C(CCC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1S(C)=O)C#N	InChI=1S/C23H18F3N3O3S/c1-28-21(16-7-6-13(12-27)10-19(16)33(2)32)20-17(8-9-18(20)30)29(22(28)31)15-5-3-4-14(11-15)23(24,25)26/h3-7,10-11,21H,8-9H2,1-2H3/t21-,33?/m1/s1	CQUQPUFUWYQFHE-GGPMTTHASA-N	211813	US9290459, 30A::US9475779, C.2A::US9670166, 30A	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2QJ7G77		aid1803512	US9475779	Oost, T; Anderskewitz, R; Gnamm, C; Hoesch, H; Morschhaeuser, G; Peters, S; Ries, UJ	10/25/2016	9/25/2017	Boehringer Ingelheim International GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=211813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=211813&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			77844887	329587693							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
438926	CN1[C@@H](C2=C(CCC2=O)N(C1=O)c1ccnc(c1)C(F)(F)F)c1ccc(cc1S(C)(=O)=O)C#N	InChI=1S/C22H17F3N4O4S/c1-28-20(14-4-3-12(11-26)9-17(14)34(2,32)33)19-15(5-6-16(19)30)29(21(28)31)13-7-8-27-18(10-13)22(23,24)25/h3-4,7-10,20H,5-6H2,1-2H3/t20-/m1/s1	CTAOATNVUQNVBF-HXUWFJFHSA-N	211812	US9290459, 29::US9475779, D.1A	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2QJ7G77		aid1803512	US9475779	Oost, T; Anderskewitz, R; Gnamm, C; Hoesch, H; Morschhaeuser, G; Peters, S; Ries, UJ	10/25/2016	9/25/2017	Boehringer Ingelheim International GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=211812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=211812&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			77844886	329587692							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439038	C[C@H]1N(CCn2c1nnc2-c1csc(C)n1)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C21H19N5OS2/c1-13-19-23-24-20(17-12-29-14(2)22-17)26(19)10-9-25(13)21(27)16-7-5-15(6-8-16)18-4-3-11-28-18/h3-8,11-13H,9-10H2,1-2H3/t13-/m1/s1	BWTVMVHFJRFVFO-CYBMUJFWSA-N	50081195	CHEMBL3422010::US10065961, Compound 1::US10683295, Compound 1::US10941151, Compound 1::US9475814, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081195&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71533722	313074297		CHEMBL3422010					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439039	C[C@H]1N(CCn2c1nnc2-c1csc(C)n1)C(=O)c1ccc(cc1)-c1ccccc1	InChI=1S/C23H21N5OS/c1-15-21-25-26-22(20-14-30-16(2)24-20)28(21)13-12-27(15)23(29)19-10-8-18(9-11-19)17-6-4-3-5-7-17/h3-11,14-15H,12-13H2,1-2H3/t15-/m1/s1	RUDNGJLEKHUVRY-OAHLLOKOSA-N	251905	US10065961, Compound 2::US10683295, Compound 2::US10941151, Compound 2::US9475814, 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251905&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549218	346546353							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439040	Cc1nc(cs1)-c1nnc2CN(CCn12)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C20H17N5OS2/c1-13-21-16(12-28-13)19-23-22-18-11-24(8-9-25(18)19)20(26)15-6-4-14(5-7-15)17-3-2-10-27-17/h2-7,10,12H,8-9,11H2,1H3	SSHIUOSPXKCYNW-UHFFFAOYSA-N	50081363	CHEMBL3422012::US10065961, Compound 3::US10683295, Compound 3::US10941151, Compound 3::US9475814, 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081363&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549359	313074310		CHEMBL3422012					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439041	FC(F)(F)c1nc(cs1)-c1nnc2CN(CCn12)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C20H14F3N5OS2/c21-20(22,23)19-24-14(11-31-19)17-26-25-16-10-27(7-8-28(16)17)18(29)13-5-3-12(4-6-13)15-2-1-9-30-15/h1-6,9,11H,7-8,10H2	UMVKCAIIJZHOQD-UHFFFAOYSA-N	251906	US10065961, Compound 4::US10683295, Compound 4::US10941151, Compound 4::US9475814, 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549358	346546354							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439042	C[C@H]1N(CCn2c1nnc2-c1coc(C)n1)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C21H19N5O2S/c1-13-19-23-24-20(17-12-28-14(2)22-17)26(19)10-9-25(13)21(27)16-7-5-15(6-8-16)18-4-3-11-29-18/h3-8,11-13H,9-10H2,1-2H3/t13-/m1/s1	HNHPUPCBAQSHTI-CYBMUJFWSA-N	251913	US10065961, Compound 11::US10683295, Compound 11::US10941151, Compound 11::US9475814, 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251913&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549500	346546361							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439043	C[C@H]1N(CCn2c1nnc2-c1nc(C)cs1)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C21H19N5OS2/c1-13-12-29-20(22-13)19-24-23-18-14(2)25(9-10-26(18)19)21(27)16-7-5-15(6-8-16)17-4-3-11-28-17/h3-8,11-12,14H,9-10H2,1-2H3/t14-/m1/s1	WZHKQWSHHGMARO-CQSZACIVSA-N	50081399	CHEMBL3422016::US10065961, Compound 19::US10683295, Compound 19::US10941151, Compound 19::US9475814, 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081399&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549637	313074312		CHEMBL3422016					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439044	C[C@H]1N(CCn2c1nnc2-c1nc(C)c(C)s1)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C22H21N5OS2/c1-13-15(3)30-21(23-13)20-25-24-19-14(2)26(10-11-27(19)20)22(28)17-8-6-16(7-9-17)18-5-4-12-29-18/h4-9,12,14H,10-11H2,1-3H3/t14-/m1/s1	KSIGHAFTVLYICN-CQSZACIVSA-N	251922	US10065961, Compound 22::US10683295, Compound 22::US10941151, Compound 22::US9475814, 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549768	346546370							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439045	C[C@H]1N(CCn2c1nnc2-c1cccc(C)n1)C(=O)c1ccc(cc1)-c1ccccc1	InChI=1S/C25H23N5O/c1-17-7-6-10-22(26-17)24-28-27-23-18(2)29(15-16-30(23)24)25(31)21-13-11-20(12-14-21)19-8-4-3-5-9-19/h3-14,18H,15-16H2,1-2H3/t18-/m1/s1	XPXDUFBCXYPOFW-GOSISDBHSA-N	251927	US10065961, Compound 29::US10683295, Compound 29::US10941151, Compound 29::US9475814, 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251927&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549912	346546375							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
439046	C[C@H]1N(CCn2c1nnc2-c1cccc(O)n1)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C22H19N5O2S/c1-14-20-24-25-21(17-4-2-6-19(28)23-17)27(20)12-11-26(14)22(29)16-9-7-15(8-10-16)18-5-3-13-30-18/h2-10,13-14H,11-12H2,1H3,(H,23,28)/t14-/m1/s1	JSJMFCNSTAYAHE-CQSZACIVSA-N	251928	US10065961, Compound 31::US10683295, Compound 31::US10941151, Compound 31::US9475814, 31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000							US Patent		10.7270/Q2B8571Q		aid1803519	US9475814	Hoveyda, HR; Dutheuil, G; Fraser, GL; Roy, M; El Bousmaqui, M; Batt, F	10/25/2016	9/25/2017	Euroscreen SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=251928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=251928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71549914	346546376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
447417	COCCOCCOCCNC(=O)c1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1	InChI=1S/C43H52N6O10S/c1-43(2,3)29-24-36(40(56-6)37(25-29)49-60(7,52)53)48-42(51)47-35-12-13-38(34-11-9-8-10-33(34)35)59-31-14-15-44-39(27-31)46-30-22-28(23-32(26-30)55-5)41(50)45-16-17-57-20-21-58-19-18-54-4/h8-15,22-27,49H,16-21H2,1-7H3,(H,44,46)(H,45,50)(H2,47,48,51)	RAYAYIHOCMLVRR-UHFFFAOYSA-N	256505	US9481648, 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>3000							US Patent		10.7270/Q24F1PNH		aid1803592	US9481648	Baker, TM; Fyfe, MC; Harbottle, GW; Hasimbegovic, V; Meghani, P; Rigby, A; Sambrook-Smith, C; Thom, SM	11/1/2016	10/30/2017	Respivert Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=256505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=256505&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274978	347916307							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
447418	COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)n2)cc(OC)c1	InChI=1S/C41H50N6O10S/c1-41(2,3)27-22-34(38(53-6)35(23-27)47-58(7,49)50)45-40(48)44-33-12-13-36(32-11-9-8-10-31(32)33)57-37-14-15-42-39(46-37)43-28-24-29(52-5)26-30(25-28)56-21-20-55-19-18-54-17-16-51-4/h8-15,22-26,47H,16-21H2,1-7H3,(H,42,43,46)(H2,44,45,48)	IEHFKZAAIWSDQM-UHFFFAOYSA-N	256506	US9481648, 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>3000							US Patent		10.7270/Q24F1PNH		aid1803592	US9481648	Baker, TM; Fyfe, MC; Harbottle, GW; Hasimbegovic, V; Meghani, P; Rigby, A; Sambrook-Smith, C; Thom, SM	11/1/2016	10/30/2017	Respivert Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=256506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=256506&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274977	347916308							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
447419	COCCOCCOCCNC(=O)c1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)n2)cc(c1)C#C	InChI=1S/C43H49N7O9S/c1-8-28-23-29(40(51)44-17-18-57-21-22-58-20-19-55-5)25-31(24-28)46-41-45-16-15-38(49-41)59-37-14-13-34(32-11-9-10-12-33(32)37)47-42(52)48-35-26-30(43(2,3)4)27-36(39(35)56-6)50-60(7,53)54/h1,9-16,23-27,50H,17-22H2,2-7H3,(H,44,51)(H,45,46,49)(H2,47,48,52)	FWXVGKSWZJEPQI-UHFFFAOYSA-N	142019	US10435361, Example 16::US8927563, I::US9481648, 16::US9790174, Example 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>3000							US Patent		10.7270/Q24F1PNH		aid1803592	US9481648	Baker, TM; Fyfe, MC; Harbottle, GW; Hasimbegovic, V; Meghani, P; Rigby, A; Sambrook-Smith, C; Thom, SM	11/1/2016	10/30/2017	Respivert Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=142019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=142019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			81689783	251920028							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
447420	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(c1)C(=O)NCCN1CCOCC1	InChI=1S/C42H49N7O8S/c1-42(2,3)28-23-35(39(55-5)36(24-28)48-58(6,52)53)47-41(51)46-34-11-12-37(33-10-8-7-9-32(33)34)57-30-13-14-43-38(26-30)45-29-21-27(22-31(25-29)54-4)40(50)44-15-16-49-17-19-56-20-18-49/h7-14,21-26,48H,15-20H2,1-6H3,(H,43,45)(H,44,50)(H2,46,47,51)	BHNGTBAKKDCSHZ-UHFFFAOYSA-N	256528	US9481648, 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>3000							US Patent		10.7270/Q24F1PNH		aid1803592	US9481648	Baker, TM; Fyfe, MC; Harbottle, GW; Hasimbegovic, V; Meghani, P; Rigby, A; Sambrook-Smith, C; Thom, SM	11/1/2016	10/30/2017	Respivert Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=256528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=256528&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86273304	347916330							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
447421	COc1c(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)c3)c3ccccc23)cc(cc1C(=O)NC1COC1)C(C)(C)C	InChI=1S/C37H37N5O5/c1-37(2,3)23-18-29(35(43)40-25-21-46-22-25)34(45-4)31(19-23)42-36(44)41-30-14-15-32(28-13-9-8-12-27(28)30)47-26-16-17-38-33(20-26)39-24-10-6-5-7-11-24/h5-20,25H,21-22H2,1-4H3,(H,38,39)(H,40,43)(H2,41,42,44)	PKPIKMRNRASAMG-UHFFFAOYSA-N	256576	US10435361, Example 75::US9481648, 75::US9790174, Example 75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>3000							US Patent		10.7270/Q24F1PNH		aid1803592	US9481648	Baker, TM; Fyfe, MC; Harbottle, GW; Hasimbegovic, V; Meghani, P; Rigby, A; Sambrook-Smith, C; Thom, SM	11/1/2016	10/30/2017	Respivert Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=256576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=256576&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			81689798	347916378							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
452005	CO[C@H]1CCC2(Cc3ccc(cc3C22N=C(N)N(CC3CCCO3)C2=O)C#N)CC1	InChI=1S/C23H28N4O3/c1-29-17-6-8-22(9-7-17)12-16-5-4-15(13-24)11-19(16)23(22)20(28)27(21(25)26-23)14-18-3-2-10-30-18/h4-5,11,17-18H,2-3,6-10,12,14H2,1H3,(H2,25,26)/t17-,18?,22?,23?	UPHWMYMEWKSHEJ-WKJJIOGWSA-N	259485	US9526727, Comparison Example Table 2, 2''-amino-4-methoxy-5''-oxo-1''-(oxolan-2-ylmethyl)-1'',5''-dihydro-3'H-dispiro[cyclohexane-1,2'-indene-1',4''-imidazole]-6'-carbonitrile	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000					7.4	35.00 C	US Patent		10.7270/Q2K936GW		aid1803657	US9526727	Bukhtiyarov, Y; Cacatian, S; Dillard, LW; Dorner-Ciossek, C; Fuchs, K; Jia, L; Lala, DS; Morales-Ramos, A; Reeves, J; Singh, SB; Venkatraman, S; Xu, Z; Yuan, J; Zhao, Y; Zheng, Y; Rast, G	12/27/2016	11/20/2017	Vitae Pharmaceutical, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=259485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=259485&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			68391757	350084179							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487352	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1	InChI=1S/C21H25ClN4O/c1-21(2,27)15-6-8-17(9-7-15)24-19-10-11-20-23-13-18(26(20)25-19)14-4-3-5-16(22)12-14/h3-5,10-13,15,17,27H,6-9H2,1-2H3,(H,24,25)/t15-,17-	BZNALBIJBHYZPW-JCNLHEQBSA-N	242380	US10047093, 8-37::US10392392, Example 8-37::US10875864, EX. 8-37::US9416132, 8-37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242380&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598035	341094631							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487353	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1	InChI=1S/C18H19ClN4O/c19-13-3-1-2-12(10-13)16-11-20-18-9-8-17(22-23(16)18)21-14-4-6-15(24)7-5-14/h1-3,8-11,14-15,24H,4-7H2,(H,21,22)/t14-,15-	OKAUIWRBORRFHW-SHTZXODSSA-N	242378	US10047093, 8-35::US10392392, Example 8-35::US10875864, EX. 8-35::US9416132, 8-35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242378&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598229	341094629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487354	OC[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1	InChI=1S/C19H21ClN4O/c20-15-3-1-2-14(10-15)17-11-21-24-9-8-18(23-19(17)24)22-16-6-4-13(12-25)5-7-16/h1-3,8-11,13,16,25H,4-7,12H2,(H,22,23)/t13-,16-	VSCPITUJYKTOSN-SAZUREKKSA-N	228355	US10047093, 8-64::US10392392, Example 8-64::US10875864, EX. 8-64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228355&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66592626	375077250							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487355	Clc1cccc(c1)-c1cnc2ccc(NC3CCOCC3)nn12	InChI=1S/C17H17ClN4O/c18-13-3-1-2-12(10-13)15-11-19-17-5-4-16(21-22(15)17)20-14-6-8-23-9-7-14/h1-5,10-11,14H,6-9H2,(H,20,21)	OEIWNDGDGDPXIO-UHFFFAOYSA-N	35052	K00152::US10047093, 8-39::US10392392, Example 8-39::US10875864, EX. 8-39::US9416132, 8-39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			6419807	85753134						ZINC28530942	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487356	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1	InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)/t15-,17-	XRNVABDYQLHODA-JCNLHEQBSA-N	242374	US10047093, 8-31::US10392392, Example 8-31::US10875864, EX. 8-31::US9416132, 8-31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242374&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598080	341094625							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487357	C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1	InChI=1S/C20H21F3N4O/c1-19(28)9-7-15(8-10-19)25-17-5-6-18-24-12-16(27(18)26-17)13-3-2-4-14(11-13)20(21,22)23/h2-6,11-12,15,28H,7-10H2,1H3,(H,25,26)/t15-,19-	SZDYHSAHSPZDEB-RHDGDCLCSA-N	242373	US10047093, 8-30::US10392392, Example 8-30::US10875864, EX. 8-30::US9416132, 8-30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242373&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598034	341094624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487358	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1	InChI=1S/C19H19F3N4O/c20-19(21,22)13-3-1-2-12(10-13)16-11-23-18-9-8-17(25-26(16)18)24-14-4-6-15(27)7-5-14/h1-3,8-11,14-15,27H,4-7H2,(H,24,25)/t14-,15-	OIWKVZIBVNRNOJ-SHTZXODSSA-N	242372	US10047093, 8-29::US10392392, Example 8-29::US10875864, EX. 8-29::US9416132, 8-29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242372&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598158	341094623							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487359	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C22H25F3N4O2/c1-21(2,30)15-6-8-16(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-17(12-14)31-22(23,24)25/h3-5,10-13,15-16,30H,6-9H2,1-2H3,(H,27,28)/t15-,16-	NMIBDYYYDQCKBY-WKILWMFISA-N	242354	US10047093, 8-10::US10392392, Example 8-10::US10875864, EX. 8-10::US9416132, 8-10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242354&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597963	341094605							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487360	C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C20H21F3N4O2/c1-19(28)9-7-14(8-10-19)25-17-5-6-18-24-12-16(27(18)26-17)13-3-2-4-15(11-13)29-20(21,22)23/h2-6,11-12,14,28H,7-10H2,1H3,(H,25,26)/t14-,19-	YVGAENJCKBRBJB-QUWSVYMGSA-N	242353	US10047093, 8-9::US10392392, Example 8-9::US10875864, EX. 8-9::US9416132, 8-9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242353&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597961	341094604							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487361	OC[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C20H21F3N4O2/c21-20(22,23)29-16-3-1-2-14(10-16)17-11-24-19-9-8-18(26-27(17)19)25-15-6-4-13(12-28)5-7-15/h1-3,8-11,13,15,28H,4-7,12H2,(H,25,26)/t13-,15-	ZFSDGASFASUELO-CTYIDZIISA-N	228294	US10047093, 8-11::US10392392, Example 8-11::US10875864, EX. 8-11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228294&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			89462288	375077207							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487362	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1	InChI=1S/C21H25ClN4O/c1-21(2,27)15-6-8-17(9-7-15)24-19-10-11-26-20(25-19)18(13-23-26)14-4-3-5-16(22)12-14/h3-5,10-13,15,17,27H,6-9H2,1-2H3,(H,24,25)/t15-,17-	QWEBKNRGVXJIKS-JCNLHEQBSA-N	50043697	CHEMBL3355987::US10047093, 8-63::US10392392, Example 8-63::US10875864, EX. 8-63::US9416132, 8-63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043697&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597997	103975081		CHEMBL3355987				ZINC13733479	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487363	O[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1	InChI=1S/C19H19F3N4O/c20-19(21,22)13-3-1-2-12(10-13)16-11-23-26-9-8-17(25-18(16)26)24-14-4-6-15(27)7-5-14/h1-3,8-11,14-15,27H,4-7H2,(H,24,25)/t14-,15-	DFHQXRLKAFZKPB-SHTZXODSSA-N	50043674	CHEMBL3355550::US10047093, 8-54::US10392392, Example 8-54::US10875864, EX. 8-54::US9416132, 8-54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043674&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598095	103975058		CHEMBL3355550				ZINC13896112	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487364	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1	InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-29-20(28-19)18(13-26-29)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)/t15-,17-	FSQNGXYJUMATLF-JCNLHEQBSA-N	50043662	CHEMBL3355552::US10047093, 8-56::US10392392, Example 8-56::US10875864, EX. 8-56::US9416132, 8-56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043662&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598153	103975046		CHEMBL3355552					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487365	O[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(OC(F)(F)F)c3)c2n1	InChI=1S/C19H19F3N4O2/c20-19(21,22)28-15-3-1-2-12(10-15)16-11-23-26-9-8-17(25-18(16)26)24-13-4-6-14(27)7-5-13/h1-3,8-11,13-14,27H,4-7H2,(H,24,25)/t13-,14-	ATMAGFPFVYJWHA-HDJSIYSDSA-N	50043690	CHEMBL3355544::US10047093, 8-46::US10392392, Example 8-46::US10875864, EX. 8-46::US9416132, 8-46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043690&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597981	103975074		CHEMBL3355544				ZINC13733469	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487366	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1	InChI=1S/C19H19F3N4O2/c20-19(21,22)28-15-3-1-2-12(10-15)16-11-23-18-9-8-17(25-26(16)18)24-13-4-6-14(27)7-5-13/h1-3,8-11,13-14,27H,4-7H2,(H,24,25)/t13-,14-	LOMZUAFMSBAHAU-HDJSIYSDSA-N	242345	US10047093, 8-1::US10392392, Example 8-1::US10875864, EX. 8-1::US9416132, 8-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242345&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24996072	341094596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
487367	FC(F)(F)Oc1cccc(c1)-c1cnc2ccc(NCC3CCS(=O)(=O)CC3)nn12	InChI=1S/C19H19F3N4O3S/c20-19(21,22)29-15-3-1-2-14(10-15)16-12-24-18-5-4-17(25-26(16)18)23-11-13-6-8-30(27,28)9-7-13/h1-5,10,12-13H,6-9,11H2,(H,23,25)	JABDFUFLQGAQCU-UHFFFAOYSA-N	242356	US10047093, 8-13::US10392392, Example 8-13::US10875864, EX. 8-13::US9416132, 8-13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q298890X		aid1795135	US10047093	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/14/2018	10/10/2018	Tolero Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242356&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598170	341094607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492325	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12)C(N)=O	InChI=1S/C25H23F2N3O3/c1-14-19(21-15(2)33-23(32)24(21,22(29)31)13-25(14,26)27)10-9-18-8-7-17(12-30-18)20-6-4-3-5-16(20)11-28/h3-10,12,14-15,19,21H,13H2,1-2H3,(H2,29,31)/b10-9+/t14-,15+,19-,21-,24+/m0/s1	NEKIZILDJUHYLI-TWOREGKPSA-N	247048	US9701669, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 43900					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247048&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117910592	376222620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492326	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccc(C)c3F)[C@H]12)C(N)=O	InChI=1S/C25H25F3N2O3/c1-13-5-4-6-19(21(13)26)16-7-8-17(30-11-16)9-10-18-14(2)25(27,28)12-24(22(29)31)20(18)15(3)33-23(24)32/h4-11,14-15,18,20H,12H2,1-3H3,(H2,29,31)/b10-9+/t14-,15+,18-,20-,24+/m0/s1	SIEHSRBCJWSMER-ZNIVZFFCSA-N	247035	(1R,3aR,6S,7R, 7aS)-5,5-difluoro- 7-((E)-2-(5- (2-fluoro-3- methylphenyl) pyridin-2- yl)vinyl)-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a- carboxamide::US9701669, 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247035&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917305	376222609							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492327	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccc(F)c3C)[C@H]12)C(N)=O	InChI=1S/C25H25F3N2O3/c1-13-18(5-4-6-20(13)26)16-7-8-17(30-11-16)9-10-19-14(2)25(27,28)12-24(22(29)31)21(19)15(3)33-23(24)32/h4-11,14-15,19,21H,12H2,1-3H3,(H2,29,31)/b10-9+/t14-,15+,19-,21-,24+/m0/s1	ZHMZFAWMFMXJDW-TWOREGKPSA-N	247036	(1R,3aR, 6S,7R,7aS)- 5,5-difluoro- 7-((E)-2-(5- (3-fluoro-2- methylphenyl) pyridin-2- yl)vinyl)-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a- carboxamide::US9701669, 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917306	376222610							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492328	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(c(C)n3)-c3ccccc3C#N)[C@H]12)C(N)=O	InChI=1S/C26H25F2N3O3/c1-14-19(22-16(3)34-24(33)25(22,23(30)32)13-26(14,27)28)10-8-18-9-11-20(15(2)31-18)21-7-5-4-6-17(21)12-29/h4-11,14,16,19,22H,13H2,1-3H3,(H2,30,32)/b10-8+/t14-,16+,19-,22-,25+/m0/s1	BZWUQBGOWKHPIR-YYAHKPHASA-N	247037	(1R,3aR,6S,7R, 7aS)-7-((E)-2-(5- (2-cyanophenyl)- 6- methylpyridin-2- yl)vinyl)-5,5- difluoro-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a- carboxamide::US9701669, 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 60000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247037&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917307	376222611							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492329	C[C@H]1OC(=O)[C@]2(CC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12	InChI=1S/C26H25F2N3O3/c1-15-20(23-16(2)34-24(33)25(23,11-22(30)32)14-26(15,27)28)10-9-19-8-7-18(13-31-19)21-6-4-3-5-17(21)12-29/h3-10,13,15-16,20,23H,11,14H2,1-2H3,(H2,30,32)/b10-9+/t15-,16+,20-,23-,25+/m0/s1	CCFUVLLOLWMZDY-PAGYRHFNSA-N	247049	US9701669, 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 60000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247049&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917316	376222621							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492330	C[C@H]1OC(=O)[C@]2(CC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccc(F)c3)[C@H]12	InChI=1S/C25H25F3N2O3/c1-14-20(9-8-19-7-6-17(12-30-19)16-4-3-5-18(26)10-16)22-15(2)33-23(32)24(22,11-21(29)31)13-25(14,27)28/h3-10,12,14-15,20,22H,11,13H2,1-2H3,(H2,29,31)/b9-8+/t14-,15+,20-,22-,24+/m0/s1	ZNHOYZRDXWYQIM-MWNBWPKCSA-N	247038	2-((1R,3aR, 6S,7R,7aS)-5,5- difluoro-7- ((E)-2-(5-(3- fluorophenyl) pyridin-2- yl)vinyl)-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a-yl)acetamide::US9701669, 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20400					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247038&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90659724	376222612							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492331	CC(C(N)=O)[C@@]12CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@@H]1[C@@H](C)OC2=O	InChI=1S/C27H27F2N3O3/c1-15-21(11-10-20-9-8-19(13-32-20)22-7-5-4-6-18(22)12-30)23-17(3)35-25(34)26(23,14-27(15,28)29)16(2)24(31)33/h4-11,13,15-17,21,23H,14H2,1-3H3,(H2,31,33)/b11-10+/t15-,16?,17+,21-,23-,26-/m0/s1	FXKUUXSFWISISL-NMVZSTGUSA-N	247039	2-((1R,3aR, 6S,7R,7aS)-7- ((E)-2-(5-(2- cyanophenyl) pyridin-2- yl)vinyl)-5,5- difluoro- 1,6-dimethyl-3- oxooctahydro- isobenzofuran- 3a- yl)propanamide::US9701669, 7::US9701669, 8::US9701669, 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 39100					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121433929	376222613							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492332	CC(C(N)=O)[C@@]12CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@@H]1[C@@H](C)OC2=O	InChI=1S/C27H27F2N3O3/c1-15-21(11-10-20-9-8-19(13-32-20)22-7-5-4-6-18(22)12-30)23-17(3)35-25(34)26(23,14-27(15,28)29)16(2)24(31)33/h4-11,13,15-17,21,23H,14H2,1-3H3,(H2,31,33)/b11-10+/t15-,16?,17+,21-,23-,26-/m0/s1	FXKUUXSFWISISL-NMVZSTGUSA-N	247039	2-((1R,3aR, 6S,7R,7aS)-7- ((E)-2-(5-(2- cyanophenyl) pyridin-2- yl)vinyl)-5,5- difluoro- 1,6-dimethyl-3- oxooctahydro- isobenzofuran- 3a- yl)propanamide::US9701669, 7::US9701669, 8::US9701669, 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26300					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121433929	376222613							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492333	CC(C(N)=O)[C@@]12CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@@H]1[C@@H](C)OC2=O	InChI=1S/C27H27F2N3O3/c1-15-21(11-10-20-9-8-19(13-32-20)22-7-5-4-6-18(22)12-30)23-17(3)35-25(34)26(23,14-27(15,28)29)16(2)24(31)33/h4-11,13,15-17,21,23H,14H2,1-3H3,(H2,31,33)/b11-10+/t15-,16?,17+,21-,23-,26-/m0/s1	FXKUUXSFWISISL-NMVZSTGUSA-N	247039	2-((1R,3aR, 6S,7R,7aS)-7- ((E)-2-(5-(2- cyanophenyl) pyridin-2- yl)vinyl)-5,5- difluoro- 1,6-dimethyl-3- oxooctahydro- isobenzofuran- 3a- yl)propanamide::US9701669, 7::US9701669, 8::US9701669, 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 59700					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121433929	376222613							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492334	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccc4OC(F)(F)Oc34)[C@H]12)C(N)=O	InChI=1S/C25H22F4N2O5/c1-12-16(19-13(2)34-22(33)23(19,21(30)32)11-24(12,26)27)9-8-15-7-6-14(10-31-15)17-4-3-5-18-20(17)36-25(28,29)35-18/h3-10,12-13,16,19H,11H2,1-2H3,(H2,30,32)/b9-8+/t12-,13+,16-,19-,23+/m0/s1	RNCJCFSBCWLWAT-QNGRFZOLSA-N	247050	US9701669, 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15400					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247050&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917324	376222622							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492335	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccnc3C#N)[C@H]12)C(N)=O	InChI=1S/C24H22F2N4O3/c1-13-17(20-14(2)33-22(32)23(20,21(28)31)12-24(13,25)26)8-7-16-6-5-15(11-30-16)18-4-3-9-29-19(18)10-27/h3-9,11,13-14,17,20H,12H2,1-2H3,(H2,28,31)/b8-7+/t13-,14+,17-,20-,23+/m0/s1	UYZBYUIKPXHJNI-INOSTWGMSA-N	247042	1R,3aR,6S, 7R,7aS)-7-((E)-2- (2&#39;-cyano-[3,3&#39;- bipyridin]-6- yl)vinyl)-5,5- difluoro-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a-carboxamide::US9701669, 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 60000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247042&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117918001	376222614							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492336	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12)N1CC(C1)C(N)=O	InChI=1S/C28H28F2N4O3/c1-16-22(10-9-21-8-7-19(12-33-21)23-6-4-3-5-18(23)11-31)24-17(2)37-26(36)27(24,15-28(16,29)30)34-13-20(14-34)25(32)35/h3-10,12,16-17,20,22,24H,13-15H2,1-2H3,(H2,32,35)/b10-9+/t16-,17+,22-,24-,27-/m0/s1	RGABGMYFMHVZDL-FMEPZHCRSA-N	247051	US9701669, 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16300					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247051&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917311	376222623							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492337	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccc(F)c3)[C@H]12)N1CC(C1)C(N)=O	InChI=1S/C27H28F3N3O3/c1-15-22(9-8-21-7-6-18(11-32-21)17-4-3-5-20(28)10-17)23-16(2)36-25(35)26(23,14-27(15,29)30)33-12-19(13-33)24(31)34/h3-11,15-16,19,22-23H,12-14H2,1-2H3,(H2,31,34)/b9-8+/t15-,16+,22-,23-,26-/m0/s1	WABUHAZRFLHFMQ-KMKRIQIBSA-N	247043	1-((1R,3aS,6S, 7R,7aS)-5,5- difluoro-7- ((E)-2-(5-(3- fluorophenyl) pyridin-2- yl)vinyl)-1,6- dimethyl-3- oxo-octahydro- isobenzofuran- 3a-yl)azetidine- 3-carboxamide::US9701669, 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247043&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117918174	376222615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492338	C[C@H]1OC(=O)[C@]2(CCC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12	InChI=1S/C27H27F2N3O3/c1-16-21(10-9-20-8-7-19(14-32-20)22-6-4-3-5-18(22)13-30)24-17(2)35-25(34)26(24,12-11-23(31)33)15-27(16,28)29/h3-10,14,16-17,21,24H,11-12,15H2,1-2H3,(H2,31,33)/b10-9+/t16-,17+,21-,24-,26+/m0/s1	LMHBOKKWURHIDN-ZPQVIKEBSA-N	247052	US9701669, 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 14400					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117918256	376222624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492339	C[C@H]1OC(=O)[C@]2(CCC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccnc3C#N)[C@H]12	InChI=1S/C26H26F2N4O3/c1-15-19(8-7-18-6-5-17(13-32-18)20-4-3-11-31-21(20)12-29)23-16(2)35-24(34)25(23,10-9-22(30)33)14-26(15,27)28/h3-8,11,13,15-16,19,23H,9-10,14H2,1-2H3,(H2,30,33)/b8-7+/t15-,16+,19-,23-,25+/m0/s1	ABPKHQVFYTVEEG-YDEUYYDZSA-N	247044	3-((1R,3aR,6S, 7R,7aS)-7 -((E)- 2- (2&#39;-cyano-[3,3&#39;- bipyridin]-6- yl)vinyl)-5,5- difluoro-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a- yl)propanamide::US9701669, 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 60000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247044&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917302	376222616							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492340	COc1ncccc1-c1ccc(\C=C\[C@@H]2[C@@H]3[C@@H](C)OC(=O)[C@]3(CC(N)=O)CC(F)(F)[C@H]2C)nc1	InChI=1S/C25H27F2N3O4/c1-14-18(21-15(2)34-23(32)24(21,11-20(28)31)13-25(14,26)27)9-8-17-7-6-16(12-30-17)19-5-4-10-29-22(19)33-3/h4-10,12,14-15,18,21H,11,13H2,1-3H3,(H2,28,31)/b9-8+/t14-,15+,18-,21-,24+/m0/s1	KQUSKRRSHXVUMC-AMPNWBNPSA-N	247045	2-((1R,3aR,6S, 7R,7aS)-5,5- difluoro-7- ((E)-2-(2&#39;- methoxy-[3,3&#39;- bipyridin]-6- yl)vinyl)-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a-yl)acetamide::US9701669, 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25900					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247045&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917304	376222617							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492341	C[C@H]1OC(=O)[C@]2(CC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccnc3C#N)[C@H]12	InChI=1S/C25H24F2N4O3/c1-14-18(22-15(2)34-23(33)24(22,10-21(29)32)13-25(14,26)27)8-7-17-6-5-16(12-31-17)19-4-3-9-30-20(19)11-28/h3-9,12,14-15,18,22H,10,13H2,1-2H3,(H2,29,32)/b8-7+/t14-,15+,18-,22-,24+/m0/s1	JRBNEHYNSKWJMK-IQRSLHTRSA-N	247046	2-((1R,3aR,6S, 7R,7aS)-7-((E)- 2- (2&#39;-cyano-[3,3&#39;- bipyridin]-6- yl)vinyl)-5,5- difluoro-1,6- dimethyl-3- oxooctahydro- isobenzofuran- 3a- yl)acetamide::US9701669, 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21900					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247046&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917303	376222618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492342	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12)NCC(N)=O	InChI=1S/C26H26F2N4O3/c1-15-20(10-9-19-8-7-18(12-31-19)21-6-4-3-5-17(21)11-29)23-16(2)35-24(34)25(23,14-26(15,27)28)32-13-22(30)33/h3-10,12,15-16,20,23,32H,13-14H2,1-2H3,(H2,30,33)/b10-9+/t15-,16+,20-,23-,25-/m0/s1	JKGPYSPHNAMFKC-UPLMCQGGSA-N	247053	US9701669, 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46800					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247053&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917313	376222625							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492343	COC(C(N)=O)[C@@]12CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@@H]1[C@@H](C)OC2=O	InChI=1S/C27H27F2N3O4/c1-15-20(11-10-19-9-8-18(13-32-19)21-7-5-4-6-17(21)12-30)22-16(2)36-25(34)26(22,14-27(15,28)29)23(35-3)24(31)33/h4-11,13,15-16,20,22-23H,14H2,1-3H3,(H2,31,33)/b11-10+/t15-,16+,20-,22-,23?,26+/m0/s1	AURWVDPCSLFJBP-KZZSQCIBSA-N	247054	US9701669, 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 47700					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247054&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917325	376222626							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492344	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12)C(O)C(N)=O	InChI=1S/C26H25F2N3O4/c1-14-19(10-9-18-8-7-17(12-31-18)20-6-4-3-5-16(20)11-29)21-15(2)35-24(34)25(21,13-26(14,27)28)22(32)23(30)33/h3-10,12,14-15,19,21-22,32H,13H2,1-2H3,(H2,30,33)/b10-9+/t14-,15+,19-,21-,22?,25+/m0/s1	UZVGVKOQRBQHDQ-LHCDKGINSA-N	247047	(S and R)-2- ((1R,3aR,6S, 7R,7aS)-7- ((E)-2-(5-(2- cyanophenyl) pyridin-2- yl)vinyl)- 5,5-difluoro- 1,6-dimethyl-3- oxooctahydro- isobenzofuran- 3a-yl)-2- hydroxyacetamide::US9701669, 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 60000					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121433941	376222619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
492345	C[C@H]1OC(=O)[C@@]2(CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)[C@H]12)C(C)(C)C(N)=O	InChI=1S/C28H29F2N3O3/c1-16-21(12-11-20-10-9-19(14-33-20)22-8-6-5-7-18(22)13-31)23-17(2)36-25(35)27(23,15-28(16,29)30)26(3,4)24(32)34/h5-12,14,16-17,21,23H,15H2,1-4H3,(H2,32,34)/b12-11+/t16-,17+,21-,23-,27-/m0/s1	HGCRUBISASDNGN-UVAATELUSA-N	247055	US9701669, 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23400					7.4	25.00 C	US Patent		10.7270/Q2PC34DS		aid1795176	US9701669	Yang, Z; Zhang, F; Dong, G; Knowles, SL; Maletic, M	7/11/2017	10/30/2018	Merck Sharp & Dohme Corp	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=247055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=247055&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117917314	376222627							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502947	Cc1cn(-c2c(Cl)cccc2Cl)c(=O)c2cnc(Nc3ccc(cc3)N3CCNCC3)nc12	InChI=1S/C24H22Cl2N6O/c1-15-14-32(22-19(25)3-2-4-20(22)26)23(33)18-13-28-24(30-21(15)18)29-16-5-7-17(8-6-16)31-11-9-27-10-12-31/h2-8,13-14,27H,9-12H2,1H3,(H,28,29,30)	WAERUNJWVBAXMQ-UHFFFAOYSA-N	264247	6-(2,6-Dichlorophenyl)-8-methyl-2-((4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264247&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297009	377003131							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502953	Cc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCNCC1	InChI=1S/C24H22Cl2N6O/c1-15-13-16(5-6-21(15)31-11-8-27-9-12-31)29-24-28-14-17-20(30-24)7-10-32(23(17)33)22-18(25)3-2-4-19(22)26/h2-7,10,13-14,27H,8-9,11-12H2,1H3,(H,28,29,30)	YEJTUDQTVDHJEO-UHFFFAOYSA-N	264252	6-(2,6-Dichlorophenyl)-2-((3-methyl-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 105							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264252&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297006	377003136							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502955	CN1CCN(CC1)c1ccc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)cc1CO	InChI=1S/C25H24Cl2N6O2/c1-31-9-11-32(12-10-31)22-6-5-17(13-16(22)15-34)29-25-28-14-18-21(30-25)7-8-33(24(18)35)23-19(26)3-2-4-20(23)27/h2-8,13-14,34H,9-12,15H2,1H3,(H,28,29,30)	HHLWIDWXYQZCBR-UHFFFAOYSA-N	264254	6-(2,6-Dichlorophenyl)-2-((3-(hydroxymethyl)-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>200							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264254&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297203	377003138							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502958	CN1CCC(CC1)c1ccc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)cc1	InChI=1S/C25H23Cl2N5O/c1-31-12-9-17(10-13-31)16-5-7-18(8-6-16)29-25-28-15-19-22(30-25)11-14-32(24(19)33)23-20(26)3-2-4-21(23)27/h2-8,11,14-15,17H,9-10,12-13H2,1H3,(H,28,29,30)	DFSAQPXRPWPPCR-UHFFFAOYSA-N	264256	6-(2,6-Dichlorophenyl)-2-((4-(1-methylpiperidin-4-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one, HCl::US9714244, 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 105							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264256&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297204	377003140							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502960	CN(C)CCc1ccc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)cc1	InChI=1S/C23H21Cl2N5O/c1-29(2)12-10-15-6-8-16(9-7-15)27-23-26-14-17-20(28-23)11-13-30(22(17)31)21-18(24)4-3-5-19(21)25/h3-9,11,13-14H,10,12H2,1-2H3,(H,26,27,28)	JAPZLEKZNSGJCE-UHFFFAOYSA-N	264257	6-(2,6-Dichlorophenyl)-2-((4-(2-(dimethylamino)ethyl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one, HCl::US9714244, 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 105							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264257&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297008	377003141							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502962	COc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCN(C)CC1	InChI=1S/C25H24Cl2N6O2/c1-31-10-12-32(13-11-31)21-7-6-16(14-22(21)35-2)29-25-28-15-17-20(30-25)8-9-33(24(17)34)23-18(26)4-3-5-19(23)27/h3-9,14-15H,10-13H2,1-2H3,(H,28,29,30)	SQDAPOIXVBVEAA-UHFFFAOYSA-N	264258	6-(2,6-Dichlorophenyl)-2-((3-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one, HCl::US9714244, 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 105							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264258&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297205	377003142							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502964	COc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCNCC1	InChI=1S/C24H22Cl2N6O2/c1-34-21-13-15(5-6-20(21)31-11-8-27-9-12-31)29-24-28-14-16-19(30-24)7-10-32(23(16)33)22-17(25)3-2-4-18(22)26/h2-7,10,13-14,27H,8-9,11-12H2,1H3,(H,28,29,30)	POKMRPKLRXBNFS-UHFFFAOYSA-N	264259	6-(2,6-Dichlorophenyl)-2-((3-methoxy-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one, HCl::US9714244, 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264259&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			85468771	377003143							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502967	CN1CCN(CC1)c1ccc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)cc1	InChI=1S/C24H22Cl2N6O/c1-30-11-13-31(14-12-30)17-7-5-16(6-8-17)28-24-27-15-18-21(29-24)9-10-32(23(18)33)22-19(25)3-2-4-20(22)26/h2-10,15H,11-14H2,1H3,(H,27,28,29)	MDIKVAKEOQZBRR-UHFFFAOYSA-N	264261	6-(2,6-Dichlorophenyl)-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 105							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264261&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297397	377003145							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502969	CNCCOc1ccc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)cc1	InChI=1S/C22H19Cl2N5O2/c1-25-10-12-31-15-7-5-14(6-8-15)27-22-26-13-16-19(28-22)9-11-29(21(16)30)20-17(23)3-2-4-18(20)24/h2-9,11,13,25H,10,12H2,1H3,(H,26,27,28)	QKLHATQBUALPMQ-UHFFFAOYSA-N	264262	6-(2,6-Dichlorophenyl)-2-((4-(2-(methylamino)ethoxy)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one, HCl::US9714244, 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264262&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297395	377003146							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502971	CC(C)N1CCN(CC1)c1ccc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)cc1	InChI=1S/C26H26Cl2N6O/c1-17(2)32-12-14-33(15-13-32)19-8-6-18(7-9-19)30-26-29-16-20-23(31-26)10-11-34(25(20)35)24-21(27)4-3-5-22(24)28/h3-11,16-17H,12-15H2,1-2H3,(H,29,30,31)	XYGHHOLKBZVZNC-UHFFFAOYSA-N	264263	6-(2,6-Dichlorophenyl)-2-((4-(4-isopropylpiperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 105							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264263&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297398	377003147							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502973	OCc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCNCC1	InChI=1S/C24H22Cl2N6O2/c25-18-2-1-3-19(26)22(18)32-9-6-20-17(23(32)34)13-28-24(30-20)29-16-4-5-21(15(12-16)14-33)31-10-7-27-8-11-31/h1-6,9,12-13,27,33H,7-8,10-11,14H2,(H,28,29,30)	TVBRIVCJUFIFCR-UHFFFAOYSA-N	264264	6-(2,6-Dichlorophenyl)-2-((3-(hydroxymethyl)-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264264&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86297396	377003148							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502975	Clc1cccc(Cl)c1-n1ccc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2c1=O	InChI=1S/C23H19Cl2N5O2/c24-18-2-1-3-19(25)21(18)30-9-8-20-17(22(30)31)14-26-23(28-20)27-15-4-6-16(7-5-15)29-10-12-32-13-11-29/h1-9,14H,10-13H2,(H,26,27,28)	KJFOURHTDLDEJK-UHFFFAOYSA-N	264265	6-(2,6-Dichlorophenyl)-2-((4-morpholinophenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264265&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86296426	377003149							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
502977	CNCc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCOCC1	InChI=1S/C25H24Cl2N6O2/c1-28-14-16-13-17(5-6-22(16)32-9-11-35-12-10-32)30-25-29-15-18-21(31-25)7-8-33(24(18)34)23-19(26)3-2-4-20(23)27/h2-8,13,15,28H,9-12,14H2,1H3,(H,29,30,31)	AKHGAEGIVMYIQH-UHFFFAOYSA-N	264266	6-(2,6-Dichlorophenyl)-2-((3-((methylamino)methyl)-4-morpholinophenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10							US Patent		10.7270/Q2GH9KZ4		aid1795320	US9714244	O Dowd, CR; Rountree, JS; Burkamp, F; Wilkinson, AJ	7/25/2017	11/15/2018	ALMAC DISCOVERY LIMITED	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=264266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=264266&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86296810	377003150							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535302	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(Cl)c(Cl)c1	InChI=1S/C16H14Cl2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-11(17)12(18)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	ZMVUVIKWZWFBIB-MRVPVSSYSA-N	242740	US10030025, Compound 1::US10836768, Cpd no 1::US9422299, 1::US9987274, Compound 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 42000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242740&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274487	341094880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535303	CCc1nsc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6OS/c1-3-13-19-16(26-22-13)15-21-20-14-10(2)23(8-9-24(14)15)17(25)11-4-6-12(18)7-5-11/h4-7,10H,3,8-9H2,1-2H3/t10-/m1/s1	UOMUYZXEONWAOD-SNVBAGLBSA-N	242741	US10030025, Compound 2::US10836768, Cpd no 2::US9422299, 2::US9987274, Compound 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242741&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274488	341094881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535304	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(Cl)cc1	InChI=1S/C16H15ClN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1	ZMIOQWILBZBCHW-SECBINFHSA-N	50112181	CHEMBL3608687::US10030025, Compound 3::US10836768, Cpd no 3::US9422299, 3::US9987274, Compound 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 66000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112181&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274489	319493540		CHEMBL3608687					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535305	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(Cl)c(F)c1	InChI=1S/C16H14ClFN6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-11(17)12(18)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	WVMPHKVLGBDWHJ-MRVPVSSYSA-N	242742	US10030025, Compound 4::US10836768, Cpd no 4::US9422299, 4::US9987274, Compound 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242742&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274490	341094882							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535306	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1	InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1	PPSNFPASKFYPMN-SECBINFHSA-N	50112244	CHEMBL3608680::US10030025, Compound 5::US10836768, Cpd no 5::US9422299, 5::US9987274, Compound 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112244&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117604931	104006697		CHEMBL3608680				ZINC29554298	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535307	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(Cl)c1	InChI=1S/C16H14ClFN6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-12(18)11(17)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	DMCGPNZWXATPEH-MRVPVSSYSA-N	242743	US10030025, Compound 6::US10836768, Cpd no 6::US9422299, 6::US9987274, Compound 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 45000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242743&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274727	341094883							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535308	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cc(F)c(F)c(F)c1	InChI=1S/C16H13F3N6OS/c1-7-13-21-22-14(15-20-8(2)23-27-15)25(13)4-3-24(7)16(26)9-5-10(17)12(19)11(18)6-9/h5-7H,3-4H2,1-2H3/t7-/m1/s1	UFMPQBXIACFWKA-SSDOTTSWSA-N	242744	US10030025, Compound 7::US10836768, Cpd no 7::US9422299, 7::US9987274, Compound 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242744&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274728	341094884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535309	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(F)c1F	InChI=1S/C16H13F3N6OS/c1-7-13-21-22-14(15-20-8(2)23-27-15)25(13)6-5-24(7)16(26)9-3-4-10(17)12(19)11(9)18/h3-4,7H,5-6H2,1-2H3/t7-/m1/s1	VKDRGGCFNJISDJ-SSDOTTSWSA-N	242745	US10030025, Compound 8::US10836768, Cpd no 8::US9422299, 8::US9987274, Compound 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242745&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274729	341094885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535310	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(F)c1	InChI=1S/C16H14F2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)10-3-4-11(17)12(18)7-10/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	VRVGLEWHAKZMDU-MRVPVSSYSA-N	242746	US10030025, Compound 9::US10836768, Cpd no 9::US9422299, 9::US9987274, Compound 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242746&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274730	341094886							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535311	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cc(F)c(F)c(F)c1F	InChI=1S/C16H12F4N6OS/c1-6-13-22-23-14(15-21-7(2)24-28-15)26(13)4-3-25(6)16(27)8-5-9(17)11(19)12(20)10(8)18/h5-6H,3-4H2,1-2H3/t6-/m1/s1	OWGILKMONFDDTK-ZCFIWIBFSA-N	242747	US10030025, Compound 10::US10836768, Cpd no 10::US9422299, 10::US9987274, Compound 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242747&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274731	341094887							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535312	Cc1nsc(n1)-c1nnc2[C@@H](CCO)N(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6O2S/c1-10-19-16(27-22-10)15-21-20-14-13(6-9-25)23(7-8-24(14)15)17(26)11-2-4-12(18)5-3-11/h2-5,13,25H,6-9H2,1H3/t13-/m1/s1	SZEYAOKHLPDWFZ-CYBMUJFWSA-N	50112245	CHEMBL3608741::US10030025, Compound 11::US10836768, Cpd no 11::US9422299, 11::US9987274, Compound 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 50000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112245&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274732	104006698		CHEMBL3608741				ZINC29556794	1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535313	CCc1noc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6O2/c1-3-13-19-16(26-22-13)15-21-20-14-10(2)23(8-9-24(14)15)17(25)11-4-6-12(18)7-5-11/h4-7,10H,3,8-9H2,1-2H3/t10-/m1/s1	AWKTWOOCLJMRQH-SNVBAGLBSA-N	242749	US10030025, Compound 13::US10836768, Cpd no 13::US9422299, 13::US9987274, Compound 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242749&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274961	341094889							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535314	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cccc(F)c1	InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)7-6-22(9)16(24)11-4-3-5-12(17)8-11/h3-5,8-9H,6-7H2,1-2H3/t9-/m1/s1	ROHADLHITYWLQW-SECBINFHSA-N	242751	US10030025, Compound 15::US10836768, Cpd no 15::US9422299, 15::US9987274, Compound 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274963	341094891							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535315	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cccc(Cl)c1	InChI=1S/C16H15ClN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)7-6-22(9)16(24)11-4-3-5-12(17)8-11/h3-5,8-9H,6-7H2,1-2H3/t9-/m1/s1	LQGKKZYSNBYZNR-SECBINFHSA-N	242752	US10030025, Compound 16::US10836768, Cpd no 16::US9422299, 16::US9987274, Compound 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274964	341094892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535316	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1cc(F)cc(F)c1	InChI=1S/C16H14F2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)4-3-23(8)16(25)10-5-11(17)7-12(18)6-10/h5-8H,3-4H2,1-2H3/t8-/m1/s1	IQKKFYUURGEICP-MRVPVSSYSA-N	242753	US10030025, Compound 17::US10836768, Cpd no 17::US9422299, 17::US9987274, Compound 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242753&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274965	341094893							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535317	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1F	InChI=1S/C16H14F2N6OS/c1-8-13-20-21-14(15-19-9(2)22-26-15)24(13)6-5-23(8)16(25)11-4-3-10(17)7-12(11)18/h3-4,7-8H,5-6H2,1-2H3/t8-/m1/s1	OZEMPZBRQPJERB-MRVPVSSYSA-N	242754	US10030025, Compound 18::US10836768, Cpd no 18::US9422299, 18::US9987274, Compound 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242754&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86274966	341094894							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535318	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccccc1	InChI=1S/C16H16N6OS/c1-10-13-18-19-14(15-17-11(2)20-24-15)22(13)9-8-21(10)16(23)12-6-4-3-5-7-12/h3-7,10H,8-9H2,1-2H3/t10-/m1/s1	HQFWWFCJWZXHFM-SNVBAGLBSA-N	50112179	CHEMBL3608740::US10030025, Compound 20::US10836768, Cpd no 20::US9422299, 20::US9987274, Compound 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 50000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112179&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275207	319493538		CHEMBL3608740					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535319	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(cc1)C(F)(F)F	InChI=1S/C17H15F3N6OS/c1-9-13-22-23-14(15-21-10(2)24-28-15)26(13)8-7-25(9)16(27)11-3-5-12(6-4-11)17(18,19)20/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1	MJAOQGKUYGSDSK-SECBINFHSA-N	242756	US10030025, Compound 21::US10836768, Cpd no 21::US9422299, 21::US9987274, Compound 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 45000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242756	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242756&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275208	341094896							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535320	CC[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1	InChI=1S/C17H17FN6OS/c1-3-13-14-20-21-15(16-19-10(2)22-26-16)24(14)9-8-23(13)17(25)11-4-6-12(18)7-5-11/h4-7,13H,3,8-9H2,1-2H3/t13-/m1/s1	OZKSTTVUQRWBIO-CYBMUJFWSA-N	242757	US10030025, Compound 22::US10836768, Cpd no 22::US9422299, 22::US9987274, Compound 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242757&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275209	341094897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535321	CCC[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1	InChI=1S/C18H19FN6OS/c1-3-4-14-15-21-22-16(17-20-11(2)23-27-17)25(15)10-9-24(14)18(26)12-5-7-13(19)8-6-12/h5-8,14H,3-4,9-10H2,1-2H3/t14-/m1/s1	GEUWDXLPGYKMAG-CQSZACIVSA-N	242759	US10030025, Compound 24::US10836768, Cpd no 24::US9422299, 24::US9987274, Compound 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 61000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275211	341094899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535322	COc1cccc(c1)C(=O)N1CCn2c(nnc2-c2nc(C)ns2)[C@H]1C	InChI=1S/C17H18N6O2S/c1-10-14-19-20-15(16-18-11(2)21-26-16)23(14)8-7-22(10)17(24)12-5-4-6-13(9-12)25-3/h4-6,9-10H,7-8H2,1-3H3/t10-/m1/s1	YKIGSSIUJRGFEY-SNVBAGLBSA-N	242762	US10030025, Compound 27::US9422299, 27::US9987274, Compound 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 70000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242762	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242762&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275448	341094902							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535323	C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(cc1)[N+]#[C-]	InChI=1S/C17H15N7OS/c1-10-14-20-21-15(16-19-11(2)22-26-16)24(14)9-8-23(10)17(25)12-4-6-13(18-3)7-5-12/h4-7,10H,8-9H2,1-2H3/t10-/m1/s1	JCZPKWYLAIALPV-SNVBAGLBSA-N	280751	(R)-4-(8-methyl-3-(3-methyl- 1,2,4-thiadiazol-5-yl)-5,6,7,8- tetrahydro-[1,2,4]triazolo[4,3- a]pyrazine-7- carbonyl)benzonitrile::US10030025, Compound 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 59000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			123859676	378162179							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535324	CCc1noc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(cc1)-c1cccs1	InChI=1S/C21H20N6O2S/c1-3-17-22-20(29-25-17)19-24-23-18-13(2)26(10-11-27(18)19)21(28)15-8-6-14(7-9-15)16-5-4-12-30-16/h4-9,12-13H,3,10-11H2,1-2H3/t13-/m1/s1	DOEVSBYTUDFXBA-CYBMUJFWSA-N	242764	US10030025, Compound 30::US10836768, Cpd no 30::US9422299, 30::US9987274, Compound 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32000							US Patent		10.7270/Q2B56MSG		aid1795617	US10030025	Hoveyda, H; Dutheuil, G; Fraser, G	7/24/2018	12/31/2018	Ogeda SA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242764	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242764&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86275451	341094904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535358	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1::US9968610, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500					7.35		US Patent		10.7270/Q26D5W1Q		aid1795619	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535360	FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C18H18F5N7/c19-17(20,14-2-1-11(7-24-14)18(21,22)23)9-30-5-3-12(4-6-30)28-15-13-8-27-29-16(13)26-10-25-15/h1-2,7-8,10,12H,3-6,9H2,(H2,25,26,27,28,29)	DPLLJMBFZXPPLZ-UHFFFAOYSA-N	280726	US10030026, Compound C-5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 31000					7.35		US Patent		10.7270/Q26D5W1Q		aid1795619	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280726&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559758	378162155							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535362	Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C17H17ClF3N7/c18-10-5-13(19)14(22-6-10)17(20,21)8-28-3-1-11(2-4-28)26-15-12-7-25-27-16(12)24-9-23-15/h5-7,9,11H,1-4,8H2,(H2,23,24,25,26,27)	NHTAIJISQFPYEN-UHFFFAOYSA-N	280732	US10030026, Compound C-16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13000					7.35		US Patent		10.7270/Q26D5W1Q		aid1795619	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280732&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559756	378162161							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535364	Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F	InChI=1S/C18H17F6N7/c19-13-5-10(18(22,23)24)6-25-14(13)17(20,21)8-31-3-1-11(2-4-31)29-15-12-7-28-30-16(12)27-9-26-15/h5-7,9,11H,1-4,8H2,(H2,26,27,28,29,30)	KZDDINPPQJQWSK-UHFFFAOYSA-N	280734	US10030026, Compound C-18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000					7.35		US Patent		10.7270/Q26D5W1Q		aid1795619	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280734&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559765	378162163							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535366	Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(cn4)C(F)(F)F)CC3)c12	InChI=1S/C19H20F5N7/c1-11-15-16(26-10-27-17(15)30-29-11)28-13-4-6-31(7-5-13)9-18(20,21)14-3-2-12(8-25-14)19(22,23)24/h2-3,8,10,13H,4-7,9H2,1H3,(H2,26,27,28,29,30)	MNOAWTHFMRYBAW-UHFFFAOYSA-N	280736	US10030026, Compound C-33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000					7.35		US Patent		10.7270/Q26D5W1Q		aid1795619	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280736&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559774	378162165							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535368	FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C18H18F5N7/c19-17(20,11-1-2-14(24-7-11)18(21,22)23)9-30-5-3-12(4-6-30)28-15-13-8-27-29-16(13)26-10-25-15/h1-2,7-8,10,12H,3-6,9H2,(H2,25,26,27,28,29)	SRWQAOQEGCZOFQ-UHFFFAOYSA-N	280737	US10030026, Compound C-127	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23000					7.35		US Patent		10.7270/Q26D5W1Q		aid1795619	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280737&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559769	378162166							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535370	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1::US9968610, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000					7.4		US Patent		10.7270/Q26D5W1Q		aid1795620	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535372	Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C17H17ClF3N7/c18-10-5-13(19)14(22-6-10)17(20,21)8-28-3-1-11(2-4-28)26-15-12-7-25-27-16(12)24-9-23-15/h5-7,9,11H,1-4,8H2,(H2,23,24,25,26,27)	NHTAIJISQFPYEN-UHFFFAOYSA-N	280732	US10030026, Compound C-16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000					7.4		US Patent		10.7270/Q26D5W1Q		aid1795620	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280732&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559756	378162161							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535374	Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F	InChI=1S/C18H17F6N7/c19-13-5-10(18(22,23)24)6-25-14(13)17(20,21)8-31-3-1-11(2-4-31)29-15-12-7-28-30-16(12)27-9-26-15/h5-7,9,11H,1-4,8H2,(H2,26,27,28,29,30)	KZDDINPPQJQWSK-UHFFFAOYSA-N	280734	US10030026, Compound C-18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11500					7.4		US Patent		10.7270/Q26D5W1Q		aid1795620	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280734&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559765	378162163							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
535376	FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C18H18F5N7/c19-17(20,11-1-2-14(24-7-11)18(21,22)23)9-30-5-3-12(4-6-30)28-15-13-8-27-29-16(13)26-10-25-15/h1-2,7-8,10,12H,3-6,9H2,(H2,25,26,27,28,29)	SRWQAOQEGCZOFQ-UHFFFAOYSA-N	280737	US10030026, Compound C-127	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2400					7.4		US Patent		10.7270/Q26D5W1Q		aid1795620	US10030026	Shapiro, G	7/24/2018	12/31/2018	Rugen Holdings (Cayman) Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280737&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559769	378162166							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548522	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US9968610, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Human		 4500					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548524	FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ccc12)c1ccc(Cl)cn1	InChI=1S/C18H19ClF2N6/c19-12-1-2-15(23-9-12)18(20,21)10-27-7-4-13(5-8-27)26-17-14-3-6-22-16(14)24-11-25-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,22,24,25,26)	QOTIEMUIZUBYME-UHFFFAOYSA-N	287587	US9567341, Compound C-3::US9968610, Compound C-3::US10420768, Compound C-3::US11752155, Compound C-3A'	Potassium voltage-gated channel subfamily H member 2	Human		 7000					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287587&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938577	378171154							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548526	Cc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H22F2N6/c1-13-2-3-16(23-10-13)19(20,21)11-27-8-5-14(6-9-27)26-18-15-4-7-22-17(15)24-12-25-18/h2-4,7,10,12,14H,5-6,8-9,11H2,1H3,(H2,22,24,25,26)	RYFZFQVKNZTNST-UHFFFAOYSA-N	287588	US9567341, Compound C-4::US9968610, Compound C-4::US10420768, Compound C-4::US11752155, Compound C-4A'	Potassium voltage-gated channel subfamily H member 2	Human		 11400					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938581	378171155							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548528	FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H19F5N6/c20-18(21,15-2-1-12(9-26-15)19(22,23)24)10-30-7-4-13(5-8-30)29-17-14-3-6-25-16(14)27-11-28-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,25,27,28,29)	NTMXMRKJKVFRLP-UHFFFAOYSA-N	287589	US9567341, Compound C-5::US9968610, Compound C-5::US10420768, Compound C-5::US11752155, Compound C-5A'	Potassium voltage-gated channel subfamily H member 2	Human		 9500					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287589&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559717	378171156							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548530	Cc1cnc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C18H21F2N7/c1-12-8-23-15(9-22-12)18(19,20)10-27-6-3-13(4-7-27)26-17-14-2-5-21-16(14)24-11-25-17/h2,5,8-9,11,13H,3-4,6-7,10H2,1H3,(H2,21,24,25,26)	OLLWXMDGFDGOBR-UHFFFAOYSA-N	287594	US9567341, Compound C-230::US9968610, Compound C-230::US10420768, Compound C-230::US11752155, Compound C-230A'	Potassium voltage-gated channel subfamily H member 2	Human		 13800					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938588	378171161							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548532	FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-2-15(26-9-12)19(22,23)24)10-30-7-4-13(5-8-30)29-17-14-3-6-25-16(14)27-11-28-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,25,27,28,29)	CSLAFKNTMSZKMA-UHFFFAOYSA-N	287596	US9567341, Compound C-127::US9968610, Compound C-127::US10420768, Compound C-127::US11752155, Compound C-127A'	Potassium voltage-gated channel subfamily H member 2	Human		 6000					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287596&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938509	378171163							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548534	Cc1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H22F2N6/c1-13-2-3-14(10-23-13)19(20,21)11-27-8-5-15(6-9-27)26-18-16-4-7-22-17(16)24-12-25-18/h2-4,7,10,12,15H,5-6,8-9,11H2,1H3,(H2,22,24,25,26)	WFXULSHSKBXRPA-UHFFFAOYSA-N	287597	US9567341, Compound C-128::US9968610, Compound C-128::US10420768, Compound C-128::US11752155, Compound C-128A'	Potassium voltage-gated channel subfamily H member 2	Human		 28000					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938568	378171164							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
548536	Fc1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H20F3N5/c20-14-3-1-13(2-4-14)19(21,22)11-27-9-6-15(7-10-27)26-18-16-5-8-23-17(16)24-12-25-18/h1-5,8,12,15H,6-7,9-11H2,(H2,23,24,25,26)	ZPTGKQWXVKFGAF-UHFFFAOYSA-N	287604	US9567341, Compound C-175::US9968610, Compound C-175::US10420768, Compound C-175::US11752155, Compound C-175A'	Potassium voltage-gated channel subfamily H member 2	Human		 4500					7.3500		US Patent		10.7270/Q2DN473N		aid1795739	US9567341	Shapiro, G	2/14/2017	1/17/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287604&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938512	378171171							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555867	NC(=O)N1CCC(CC1)c1c(-c2ccc(N)nc2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C24H23ClN6O/c25-17-2-4-18(5-3-17)31-20-14-28-10-7-19(20)22(15-8-11-30(12-9-15)24(27)32)23(31)16-1-6-21(26)29-13-16/h1-7,10,13-15H,8-9,11-12H2,(H2,26,29)(H2,27,32)	JMEGFTLLJFBFCF-UHFFFAOYSA-N	291367	US9580415, Example 1::4-[2-(6-Aminopyridin-3-yl)-1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291367	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291367&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			85469609	381611671							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555869	NC(=O)N1CCC(CC1)c1c(-c2cccnc2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C24H22ClN5O/c25-18-3-5-19(6-4-18)30-21-15-28-11-7-20(21)22(23(30)17-2-1-10-27-14-17)16-8-12-29(13-9-16)24(26)31/h1-7,10-11,14-16H,8-9,12-13H2,(H2,26,31)	WZBSBFMKRPNPGH-UHFFFAOYSA-N	291368	US9580415, Example 2::4-[1-(4-Chlorophenyl)-2- (pyridin-3-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide; formic acid	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291368	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291368&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118576907	381611672							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555872	COc1cc(ccn1)-c1c(C2CCN(CC2)C(N)=O)c2ccncc2n1-c1ccc(Cl)cc1	InChI=1S/C25H24ClN5O2/c1-33-22-14-17(6-11-29-22)24-23(16-8-12-30(13-9-16)25(27)32)20-7-10-28-15-21(20)31(24)19-4-2-18(26)3-5-19/h2-7,10-11,14-16H,8-9,12-13H2,1H3,(H2,27,32)	FPBZXJSGQZWMOF-UHFFFAOYSA-N	291370	US9580415, Example 4::4-[1-(4-Chlorophenyl)-2-(2- methoxypyridin-4-yl)-1H- pyrrolo[2,3-c]pyridin-3- yl]piperidine-1-carboxamide; formic acid	Potassium voltage-gated channel subfamily H member 2	Human		 550					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291370	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291370&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86268870	381611674							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555875	NC(=O)N1CCC(CC1)c1c(-c2ccc(nc2)N2CCOCC2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C28H29ClN6O2/c29-21-2-4-22(5-3-21)35-24-18-31-10-7-23(24)26(19-8-11-34(12-9-19)28(30)36)27(35)20-1-6-25(32-17-20)33-13-15-37-16-14-33/h1-7,10,17-19H,8-9,11-16H2,(H2,30,36)	OHIOTXRHBWRBLU-UHFFFAOYSA-N	291372	US9580415, Example 6::4-[1-(4-Chlorophenyl)-2-[6- (morpholin-4-yl)pyridin-3-yl]- 1H-pyrrolo[2,3-c]pyridin-3- yl]piperidine-1-carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		 550					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291372&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86268872	381611676							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555877	NC(=O)N1CCC(CC1)c1c(-c2cncnc2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C23H21ClN6O/c24-17-1-3-18(4-2-17)30-20-13-26-8-5-19(20)21(22(30)16-11-27-14-28-12-16)15-6-9-29(10-7-15)23(25)31/h1-5,8,11-15H,6-7,9-10H2,(H2,25,31)	MCKPHCFFVZXCNO-UHFFFAOYSA-N	291373	US9580415, Example 7::4-[1-(4-Chlorophenyl)-2- (pyrimidin-5-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291373&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86268868	381611677							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555879	NC(=O)N1CCC(CC1)c1c(-c2cc[nH]n2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C22H21ClN6O/c23-15-1-3-16(4-2-15)29-19-13-25-9-5-17(19)20(21(29)18-6-10-26-27-18)14-7-11-28(12-8-14)22(24)30/h1-6,9-10,13-14H,7-8,11-12H2,(H2,24,30)(H,26,27)	AKKCOZNNTASACZ-UHFFFAOYSA-N	291374	US9580415, Example 8::4-[1-(4-Chlorophenyl)-2-(1H- pyrazol-3-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291374&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269065	381611678							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555881	NC(=O)N1CCC(CC1)c1c(-c2cn[nH]c2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C22H21ClN6O/c23-16-1-3-17(4-2-16)29-19-13-25-8-5-18(19)20(21(29)15-11-26-27-12-15)14-6-9-28(10-7-14)22(24)30/h1-5,8,11-14H,6-7,9-10H2,(H2,24,30)(H,26,27)	STPFGQBPKLNYMU-UHFFFAOYSA-N	291375	US9580415, Example 9::4-[1-(4-Chlorophenyl)-2-(1H- pyrazo1-4-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		>10000					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291375&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269066	381611679							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555884	Cn1nccc1-c1c(C2CCN(CC2)C(N)=O)c2ccncc2n1-c1ccc(Cl)cc1 |(2.61,2.11,;3.01,.62,;4.47,.15,;4.47,-1.39,;3.01,-1.87,;2.1,-.62,;.56,-.62,;-.34,.62,;.06,2.11,;1.54,2.51,;1.94,4,;.85,5.09,;-.63,4.69,;-1.03,3.2,;1.25,6.57,;2.74,6.97,;.16,7.66,;-1.81,.15,;-3.14,.92,;-4.47,.15,;-4.47,-1.39,;-3.14,-2.16,;-1.81,-1.39,;-.34,-1.87,;.43,-3.2,;-.66,-4.29,;-.26,-5.78,;1.23,-6.18,;1.62,-7.66,;2.31,-5.09,;1.92,-3.6,)|	InChI=1S/C23H23ClN6O/c1-28-19(7-11-27-28)22-21(15-8-12-29(13-9-15)23(25)31)18-6-10-26-14-20(18)30(22)17-4-2-16(24)3-5-17/h2-7,10-11,14-15H,8-9,12-13H2,1H3,(H2,25,31)	AJJVTOMIBFGUBX-UHFFFAOYSA-N	291377	US9580415, Example 11::4-[1-(4-Chlorophenyl)-2-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291377	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291377&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269068	381611681							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555886	Cn1cncc1-c1c(C2CCN(CC2)C(N)=O)c2ccncc2n1-c1ccc(Cl)cc1 |(2.24,-3.12,;3.01,-1.79,;4.47,-1.31,;4.47,.23,;3.01,.7,;2.1,-.54,;.56,-.54,;-.34,.7,;.06,2.19,;-1.03,3.28,;-.63,4.77,;.85,5.16,;1.94,4.08,;1.54,2.59,;1.25,6.65,;2.74,7.05,;.16,7.74,;-1.81,.23,;-3.14,1,;-4.47,.23,;-4.47,-1.31,;-3.14,-2.08,;-1.81,-1.31,;-.34,-1.79,;.06,-3.28,;-1.03,-4.37,;-.63,-5.85,;.85,-6.25,;1.25,-7.74,;1.94,-5.16,;1.54,-3.68,)|	InChI=1S/C23H23ClN6O/c1-28-14-27-13-20(28)22-21(15-7-10-29(11-8-15)23(25)31)18-6-9-26-12-19(18)30(22)17-4-2-16(24)3-5-17/h2-6,9,12-15H,7-8,10-11H2,1H3,(H2,25,31)	GGUIKURETGJHSC-UHFFFAOYSA-N	291378	US9580415, Example 12::4-[1-(4-Chlorophenyl)-2-(1- methyl-1H-imidazol-5-yl)-1H- pyrrolo[2,3-c]pyridin-3- yl]piperidine-1-carboxamide	Potassium voltage-gated channel subfamily H member 2	Human		>10000					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291378&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269069	381611682							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555888	NC(=O)N1CCC(CC1)c1c(-n2cccn2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C22H21ClN6O/c23-16-2-4-17(5-3-16)29-19-14-25-10-6-18(19)20(21(29)28-11-1-9-26-28)15-7-12-27(13-8-15)22(24)30/h1-6,9-11,14-15H,7-8,12-13H2,(H2,24,30)	IWXGNZDKSOBNRG-UHFFFAOYSA-N	291379	US9580415, Example 13::4-[1-(4-Chlorophenyl)-2-(1H- pyrazol-1-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide; formic acid	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291379	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291379&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269070	381611683							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555890	NC(=O)N1CCC(CC1)c1c(-n2ccnc2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C22H21ClN6O/c23-16-1-3-17(4-2-16)29-19-13-25-8-5-18(19)20(21(29)28-12-9-26-14-28)15-6-10-27(11-7-15)22(24)30/h1-5,8-9,12-15H,6-7,10-11H2,(H2,24,30)	CZPSCVYHKPRPAS-UHFFFAOYSA-N	291380	US9580415, Example 14::4-[1-(4-Chlorophenyl)-2-(1H- imidazol-1-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide; bis(formic acid)	Potassium voltage-gated channel subfamily H member 2	Human		>10000					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291380&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269273	381611684							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555894	Clc1ccc(cc1)-n1c(c(C2CCNCC2)c2ccncc12)-c1ccncc1	InChI=1S/C23H21ClN4/c24-18-1-3-19(4-2-18)28-21-15-27-14-9-20(21)22(16-5-10-25-11-6-16)23(28)17-7-12-26-13-8-17/h1-4,7-9,12-16,25H,5-6,10-11H2	CEKOEQQZORJQPM-UHFFFAOYSA-N	291383	US9580415, Example 17::4-[1-(4-Chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrolo[2,3-c]pyridin-2-yl]pyridine	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291383	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291383&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269276	381611687							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555896	Nc1ccc(cn1)-c1c(C2CCNCC2)c2ccncc2n1-c1ccc(Cl)cc1	InChI=1S/C23H22ClN5/c24-17-2-4-18(5-3-17)29-20-14-27-12-9-19(20)22(15-7-10-26-11-8-15)23(29)16-1-6-21(25)28-13-16/h1-6,9,12-15,26H,7-8,10-11H2,(H2,25,28)	RTQLWGNETFXQIL-UHFFFAOYSA-N	291384	US9580415, Example 18::5-[1-(4-Chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrolo[2,3-c]pyridin-2-yl]pyridin-2-amine	Potassium voltage-gated channel subfamily H member 2	Human		>10000					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291384	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291384&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269277	381611688							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555898	CN(C)Cc1c(-c2ccncc2)n(-c2ccc(Cl)cc2)c2cnccc12	InChI=1S/C21H19ClN4/c1-25(2)14-19-18-9-12-24-13-20(18)26(17-5-3-16(22)4-6-17)21(19)15-7-10-23-11-8-15/h3-13H,14H2,1-2H3	GONCOLJMAFSBKX-UHFFFAOYSA-N	291385	US9580415, Example 19::{[1-(4-Chlorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]methyl}dimethyl amine	Potassium voltage-gated channel subfamily H member 2	Human		 5500					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291385	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291385&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86269278	381611689							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
555901	Clc1ccc(cc1)-n1c(-c2nn[nH]n2)c(C2CCNCC2)c2ccncc12	InChI=1S/C19H18ClN7/c20-13-1-3-14(4-2-13)27-16-11-22-10-7-15(16)17(12-5-8-21-9-6-12)18(27)19-23-25-26-24-19/h1-4,7,10-12,21H,5-6,8-9H2,(H,23,24,25,26)	AHLQRTLCEXENBT-UHFFFAOYSA-N	291387	US9580415, Example 21::4-[1-(4-Chlorophenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine; bis(trifluoroacetic acid)	Potassium voltage-gated channel subfamily H member 2	Human		>10000					7.3000	25.00 C	US Patent		10.7270/Q2DB83X5		aid1795861	US9580415	Patient, L; Evans, D; Simpson, I; Powell, A	2/28/2017	2/19/2019	Proximagen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291387	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291387&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137528698	381611691							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571677	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1C(O)=O	InChI=1S/C36H37N5O8S/c1-36(2,3)21-17-28(33(48-5)29(18-21)41-50(6,45)46)40-35(44)39-27-13-14-30(25-10-8-7-9-24(25)27)49-23-15-16-37-32(20-23)38-22-11-12-26(34(42)43)31(19-22)47-4/h7-20,41H,1-6H3,(H,37,38)(H,42,43)(H2,39,40,44)	QFXFIEVXAUEHEV-UHFFFAOYSA-N	255476	US9499486, 1::US10125100, Example 1::US9751837, Example 1::US10392346, Example 1::US10941115, Example 1	Potassium voltage-gated channel subfamily H member 2	Human		>3300							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=255476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=255476&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121249201	347830111							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571678	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1C(=O)NCCN1CCOCC1	InChI=1S/C42H49N7O8S/c1-42(2,3)27-23-34(39(55-5)35(24-27)48-58(6,52)53)47-41(51)46-33-13-14-36(31-10-8-7-9-30(31)33)57-29-15-16-43-38(26-29)45-28-11-12-32(37(25-28)54-4)40(50)44-17-18-49-19-21-56-22-20-49/h7-16,23-26,48H,17-22H2,1-6H3,(H,43,45)(H,44,50)(H2,46,47,51)	BPROBXOFSXWRJR-UHFFFAOYSA-N	298375	US10125100, Example 2::4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2-methoxy-N-(2-morpholinoethyl)benzamide::US9751837, Example 17(u)::US10392346, Example 2::US10941115, Example 2	Potassium voltage-gated channel subfamily H member 2	Human		>3300							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298375	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298375&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255251	381621197							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571679	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1C(=O)NC1CCN(C)CC1	InChI=1S/C42H49N7O7S/c1-42(2,3)26-22-34(39(55-6)35(23-26)48-57(7,52)53)47-41(51)46-33-14-15-36(31-11-9-8-10-30(31)33)56-29-16-19-43-38(25-29)44-28-12-13-32(37(24-28)54-5)40(50)45-27-17-20-49(4)21-18-27/h8-16,19,22-25,27,48H,17-18,20-21H2,1-7H3,(H,43,44)(H,45,50)(H2,46,47,51)	PTMVPXQFPYJIMN-UHFFFAOYSA-N	298404	US10125100, Example 17(j)::4-[[4-[[4-[[5-tert-butyl-3-(methanesulfonamido)-2-methoxy-phenyl]carbamoylamino]-1-naphthyl]oxy]-2-pyridyl]amino]-2-methoxy-N-(1-methyl-4-piperidyl)benzamide::US9751837, Example 17(j)::US10392346, Example 17(j)::US10941115, Example 17(j)	Potassium voltage-gated channel subfamily H member 2	Human		>3300							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298404	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298404&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255377	381621226							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571680	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1C(=O)NCCN1CCN(C)CC1	InChI=1S/C44H54N8O8S/c1-44(2,3)28-23-34(41(59-7)35(24-28)50-61(8,55)56)49-43(54)48-33-13-14-36(32-12-10-9-11-31(32)33)60-30-15-16-45-39(27-30)47-29-25-37(57-5)40(38(26-29)58-6)42(53)46-17-18-52-21-19-51(4)20-22-52/h9-16,23-27,50H,17-22H2,1-8H3,(H,45,47)(H,46,53)(H2,48,49,54)	KLCRZBNGDBKHFA-UHFFFAOYSA-N	298439	US10125100, Example 22::4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2,6-dimethoxy-N-(2-(4-methylpiperazin-1-yl)ethyl)benzamide::US9751837, Example 22::US10392346, Example 22::US10941115, Example 22	Potassium voltage-gated channel subfamily H member 2	Human		>3700							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298439&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255467	381621261							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571681	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1C(=O)NCCOCCOCCO	InChI=1S/C43H52N6O11S/c1-43(2,3)27-22-33(40(57-6)34(23-27)49-61(7,53)54)48-42(52)47-32-12-13-35(31-11-9-8-10-30(31)32)60-29-14-15-44-38(26-29)46-28-24-36(55-4)39(37(25-28)56-5)41(51)45-16-18-58-20-21-59-19-17-50/h8-15,22-26,49-50H,16-21H2,1-7H3,(H,44,46)(H,45,51)(H2,47,48,52)	NZIUKWCXTXDJLH-UHFFFAOYSA-N	298441	US10125100, Example 36::4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-N-(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)-2,6-dimethoxybenzamide::US9751837, Example 36::US10392346, Example 36::US10941115, Example 36	Potassium voltage-gated channel subfamily H member 2	Human		>11000							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298441&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255444	381621263							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571682	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NC(=O)CO)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1C(=O)NCCN1CCS(=O)CC1	InChI=1S/C43H49N7O8S/c1-43(2,3)27-22-34(47-39(52)26-51)40(57-5)35(23-27)49-42(54)48-33-12-13-36(31-9-7-6-8-30(31)33)58-29-14-15-44-38(25-29)46-28-10-11-32(37(24-28)56-4)41(53)45-16-17-50-18-20-59(55)21-19-50/h6-15,22-25,51H,16-21,26H2,1-5H3,(H,44,46)(H,45,53)(H,47,52)(H2,48,49,54)	KPESYVJNOVNDGE-UHFFFAOYSA-N	298444	US10125100, Example 41::4-((4-((4-(3-(5-(tert-Butyl)-3-(2-hydroxyacetamido)-2-methoxyphenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2-methoxy-N-(2-(1-oxidothiomorpholino)ethyl)benzamide::US9751837, Example 41::US10392346, Example 41::US10941115, Example 41	Potassium voltage-gated channel subfamily H member 2	Human		>11000							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298444&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255259	381621266							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571683	CCOP(C)(=O)c1ccc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc1OC	InChI=1S/C38H44N5O8PS/c1-9-50-52(7,45)34-17-14-25(22-33(34)48-5)40-35-23-26(18-19-39-35)51-32-16-15-29(27-12-10-11-13-28(27)32)41-37(44)42-30-20-24(38(2,3)4)21-31(36(30)49-6)43-53(8,46)47/h10-23,43H,9H2,1-8H3,(H,39,40)(H2,41,42,44)	SIKCUPWQHPKKSN-UHFFFAOYSA-N	298451	US10125100, Example 43::Ethyl (4-((4-((4-(3-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2-methoxyphenyl)(methyl)phosphinate	Potassium voltage-gated channel subfamily H member 2	Human		>11000							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298451&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121276347	381621273							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571684	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1P(C)(O)=O	InChI=1S/C36H40N5O8PS/c1-36(2,3)22-18-28(34(48-5)29(19-22)41-51(7,45)46)40-35(42)39-27-13-14-30(26-11-9-8-10-25(26)27)49-24-16-17-37-33(21-24)38-23-12-15-32(50(6,43)44)31(20-23)47-4/h8-21,41H,1-7H3,(H,37,38)(H,43,44)(H2,39,40,42)	SUXULCDTOIYHQM-UHFFFAOYSA-N	298446	US10125100, Example 44::(4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2-methoxyphenyl)(methyl)phosphinic acid::US9751837, Example 44::US10392346, Example 44::US10941115, Example 44	Potassium voltage-gated channel subfamily H member 2	Human		>11000							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298446&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255266	381621268							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571685	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1C(=O)NCCOCCOCCOP(O)(O)=O	InChI=1S/C43H53N6O14PS/c1-43(2,3)27-22-33(40(59-6)34(23-27)49-65(7,55)56)48-42(51)47-32-12-13-35(31-11-9-8-10-30(31)32)63-29-14-15-44-38(26-29)46-28-24-36(57-4)39(37(25-28)58-5)41(50)45-16-17-60-18-19-61-20-21-62-64(52,53)54/h8-15,22-26,49H,16-21H2,1-7H3,(H,44,46)(H,45,50)(H2,47,48,51)(H2,52,53,54)	AFFDEZDCXSAKBU-UHFFFAOYSA-N	298449	US10125100, Example 47::2-(2-(2-(4-((4-((4-(3-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)-naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2,6-dimethoxybenzamido)ethoxy)ethoxy)ethyl dihydrogen phosphate::US9751837, Example 47::US10392346, Example 47::US10941115, Example 47	Potassium voltage-gated channel subfamily H member 2	Human		>11000							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298449&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255405	381621271							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
571686	COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(N(CCO)S(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)ccc1C(=O)NCCN1CCS(=O)CC1	InChI=1S/C44H53N7O9S2/c1-44(2,3)29-25-36(41(59-5)37(26-29)51(19-22-52)62(6,56)57)49-43(54)48-35-13-14-38(33-10-8-7-9-32(33)35)60-31-15-16-45-40(28-31)47-30-11-12-34(39(27-30)58-4)42(53)46-17-18-50-20-23-61(55)24-21-50/h7-16,25-28,52H,17-24H2,1-6H3,(H,45,47)(H,46,53)(H2,48,49,54)	KAXFCXIHQXDECG-UHFFFAOYSA-N	298450	US10125100, Example 48::4-((4-((4-(3-(5-(tert-Butyl)-3-(N-(2-hydroxyethyl)methylsulfonamido)-2-methoxyphenyl)-ureido)naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2-methoxy-N-(2-(1-oxidothiomorpholino)-ethyl)benzamide::US9751837, Example 48::US10392346, Example 48::US10941115, Example 48	Potassium voltage-gated channel subfamily H member 2	Human		>11000							US Patent		10.7270/Q2XW4MV4		aid1796010	US10125100	Baker, TM; Fyfe, MC; Jones, G; Thom, SM	11/13/2018	3/11/2019	Topivert Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=298450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=298450&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			121255417	381621272							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576007	COCC(F)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(NC2CN(CCCF)C2)cc1OC |r|	InChI=1S/C28H36F3N5O2/c1-18-11-23-21(7-8-25-24(23)13-32-34-25)27(36(18)16-28(30,31)17-37-2)22-6-5-19(12-26(22)38-3)33-20-14-35(15-20)10-4-9-29/h5-8,12-13,18,20,27,33H,4,9-11,14-17H2,1-3H3,(H,32,34)	FDUQYLYBWZAWAD-UHFFFAOYSA-N	300919	N-(4-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-3-methoxyphenyl)-1-(3-fluoropropyl)azetidin-3-amine::US10131663, Example 1::US10590130, Example 1::US10961241, Example 1	Potassium voltage-gated channel subfamily H member 2	Human		 10000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453447	381749678							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576008	COCC(F)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C26H33F3N6O/c1-17-10-21-20(5-7-23-22(21)12-31-33-23)25(35(17)15-26(28,29)16-36-2)24-6-4-18(11-30-24)32-19-13-34(14-19)9-3-8-27/h4-7,11-12,17,19,25,32H,3,8-10,13-16H2,1-2H3,(H,31,33)	BFXKWHZHXIVGOE-UHFFFAOYSA-N	300921	6-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-N-(1-(3-fluoropropyl)azetidin-3-yl)pyridin-3-amine::US10131663, Example 2::US10590130, Example 2::US10961241, Example 2	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300921	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300921&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453459	381749680							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576009	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C26H32F2N6/c1-17-11-21-20(4-6-23-22(21)13-30-32-23)25(34(17)16-26(28)7-8-26)24-5-3-18(12-29-24)31-19-14-33(15-19)10-2-9-27/h3-6,12-13,17,19,25,31H,2,7-11,14-16H2,1H3,(H,30,32)	PHBYNJGKPFJBPE-UHFFFAOYSA-N	300924	6-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-N-(1-(3-fluoropropyl)azetidin-3-yl)pyridin-3-amine::US10131663, Example 3::US10590130, Example 3::US10961241, Example 3	Potassium voltage-gated channel subfamily H member 2	Human		>36000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300924	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300924&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137553987	381749683							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576010	COCC(C)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(NC2CN(CCCF)C2)cc1OC |r|	InChI=1S/C29H39F2N5O2/c1-19-12-24-22(8-9-26-25(24)14-32-34-26)28(36(19)17-29(2,31)18-37-3)23-7-6-20(13-27(23)38-4)33-21-15-35(16-21)11-5-10-30/h6-9,13-14,19,21,28,33H,5,10-12,15-18H2,1-4H3,(H,32,34)	RJVPOCVCIFLEDC-UHFFFAOYSA-N	300925	N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-3-methoxyphenyl)-1-(3-fluoropropyl)azetidin-3-amine (diastereoisomeric mixture)::US10131663, Example 4::US10590130, Example 4::US10961241, Example 4	Potassium voltage-gated channel subfamily H member 2	Human		 17000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300925	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300925&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137553988	381749684							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576011	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)CO)c1c(F)cc(NC2CN(CCCF)C2)cc1F |r|	InChI=1S/C26H30F5N5O/c1-15-7-19-18(3-4-23-20(19)10-32-34-23)25(36(15)13-26(30,31)14-37)24-21(28)8-16(9-22(24)29)33-17-11-35(12-17)6-2-5-27/h3-4,8-10,15,17,25,33,37H,2,5-7,11-14H2,1H3,(H,32,34)	PBTFDTKJUCHOCI-UHFFFAOYSA-N	300929	3-((6S,8R)-6-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-8-methyl-3,6,8,9-tetrahydro-7H-pyrazolo[4,3-f]isoquinolin-7-yl)-2,2-difluoropropan-1-ol::US10131663, Example 5::US10590130, Example 5::US10961241, Example 5	Potassium voltage-gated channel subfamily H member 2	Human		 13000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300929	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300929&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137553993	381749688							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576012	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C28H35F2N5O/c1-18-12-23-21(6-7-25-24(23)14-31-33-25)27(35(18)17-28(30)8-9-28)22-5-4-19(13-26(22)36-2)32-20-15-34(16-20)11-3-10-29/h4-7,13-14,18,20,27,32H,3,8-12,15-17H2,1-2H3,(H,31,33)	YZMMWVWLDOCLCK-UHFFFAOYSA-N	300930	N-(4-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-3-methoxyphenyl)-1-(3-fluoropropyl)azetidin-3-amine::US10131663, Example 6::US10590130, Example 6::US10961241, Example 6	Potassium voltage-gated channel subfamily H member 2	Human		 9100							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300930	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300930&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453461	381749689							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576013	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)CO)c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H31F3N6O/c1-16-9-20-19(4-6-22-21(20)11-30-32-22)24(34(16)14-25(27,28)15-35)23-5-3-17(10-29-23)31-18-12-33(13-18)8-2-7-26/h3-6,10-11,16,18,24,31,35H,2,7-9,12-15H2,1H3,(H,30,32)	MKAPFCBLWCECBI-UHFFFAOYSA-N	300950	2,2-difluoro-3-((6S,8R)-6-(5-((1-(3-fluoropropyl)azetidin-3-yl)amino)pyridin-2-yl)-8-methyl-3,6,8,9-tetrahydro-7H-pyrazolo[4,3-f]isoquinolin-7-yl)propan-1-ol::US10131663, Example 16::US10590130, Example 16::US10961241, Example 16	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300950&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453497	381749709							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576014	C[C@H](Cc1cccc(N)c1C)NC(=O)C(F)(F)F |r|	InChI=1S/C12H15F3N2O/c1-7(17-11(18)12(13,14)15)6-9-4-3-5-10(16)8(9)2/h3-5,7H,6,16H2,1-2H3,(H,17,18)	MHTDCZHUHNZKNA-UHFFFAOYSA-N	300951	N-[1-(3-fluoropropyl)azetidin-3-yl]-6-[(6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-3,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]pyridin-3-amine::US10131663, Example 17	Potassium voltage-gated channel subfamily H member 2	Human		 22000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300951	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300951&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453502	381749710							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576015	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1ncc(NC2CN(CCCF)C2)cc1F |r|	InChI=1S/C26H31F3N6/c1-16-9-20-19(3-4-23-21(20)12-31-33-23)25(35(16)15-26(29)5-6-26)24-22(28)10-17(11-30-24)32-18-13-34(14-18)8-2-7-27/h3-4,10-12,16,18,25,32H,2,5-9,13-15H2,1H3,(H,31,33)	CZXRKQNLGWTZPP-UHFFFAOYSA-N	300952	5-fluoro-6-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-N-(1-(3-fluoropropyl)azetidin-3-yl)pyridin-3-amine::US10131663, Example 18::US10590130, Example 18::US10961241, Example 18	Potassium voltage-gated channel subfamily H member 2	Human		>38000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300952&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453504	381749711							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576016	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(C)(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C27H34F3N5O/c1-17-11-22-20(7-8-24-23(22)13-31-33-24)26(35(17)16-27(2,29)30)21-6-5-18(12-25(21)36-3)32-19-14-34(15-19)10-4-9-28/h5-8,12-13,17,19,26,32H,4,9-11,14-16H2,1-3H3,(H,31,33)	PPMFNADUOOVZPG-UHFFFAOYSA-N	300953	N-(4-((6S,8R)-7-(2,2-difluoropropyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-3-methoxyphenyl)-1-(3-fluoropropyl)azetidin-3-amine::US10131663, Example 19::US10590130, Example 19::US10961241, Example 19	Potassium voltage-gated channel subfamily H member 2	Human		 5400							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453506	381749712							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576017	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C26H32F3N5O/c1-16-10-21-19(6-7-23-22(21)12-30-32-23)26(34(16)15-25(28)29)20-5-4-17(11-24(20)35-2)31-18-13-33(14-18)9-3-8-27/h4-7,11-12,16,18,25-26,31H,3,8-10,13-15H2,1-2H3,(H,30,32)	IVBCTFVBWGUGKC-UHFFFAOYSA-N	300955	N-(4-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-3-methoxyphenyl)-1-(3-fluoropropyl)azetidin-3-amine::US10131663, Example 21::US10590130, Example 21::US10961241, Example 21	Potassium voltage-gated channel subfamily H member 2	Human		 5300							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300955	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300955&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453518	381749714							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576018	C[C@@H]5Cc1c(ccc2[nH]ncc12)[C@@H](c4ccc(NC3CN(CCCF)C3)cn4)N5CC(F)F	InChI=1S/C24H29F3N6/c1-15-9-19-18(4-6-21-20(19)11-29-31-21)24(33(15)14-23(26)27)22-5-3-16(10-28-22)30-17-12-32(13-17)8-2-7-25/h3-6,10-11,15,17,23-24,30H,2,7-9,12-14H2,1H3,(H,29,31)	LCCYGLSQPCXNFG-UHFFFAOYSA-N	300959	6-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-N-(1-(3-fluoropropyl)azetidin-3-yl)pyridin-3-amine::US10131663, Example 25::US10590130, Example 25::US10961241, Example 25	Potassium voltage-gated channel subfamily H member 2	Human		 28000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134459023	381749718							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576019	C[C@@H]5Cc1c(ccc2[nH]ncc12)[C@@H](c4ccc(NC3CN(CCCF)C3)cc4)N5CC(F)(F)F	InChI=1S/C25H29F4N5/c1-16-11-21-20(7-8-23-22(21)12-30-32-23)24(34(16)15-25(27,28)29)17-3-5-18(6-4-17)31-19-13-33(14-19)10-2-9-26/h3-8,12,16,19,24,31H,2,9-11,13-15H2,1H3,(H,30,32)	RDIWNJDCZLGDOS-UHFFFAOYSA-N	300961	1-(3-Fluoropropyl)-N-(4-((6R,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)phenyl)azetidin-3-amine::US10131663, Example 27::US10590130, Example 27::US10961241, Example 27	Potassium voltage-gated channel subfamily H member 2	Human		 7900							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134458798	381749720							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576020	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C26H31F4N5O/c1-16-10-21-19(6-7-23-22(21)12-31-33-23)25(35(16)15-26(28,29)30)20-5-4-17(11-24(20)36-2)32-18-13-34(14-18)9-3-8-27/h4-7,11-12,16,18,25,32H,3,8-10,13-15H2,1-2H3,(H,31,33)	JUMJODAYGHYIAH-UHFFFAOYSA-N	300962	1-(3-fluoropropyl)-N-(3-methoxy-4-((6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)phenyl)azetidin-3-amine::US10131663, Example 28::US10590130, Example 28::US10961241, Example 28	Potassium voltage-gated channel subfamily H member 2	Human		 7800							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300962&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554001	381749721							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576021	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1ccc(NC2CN(CCCF)C2)c(F)n1 |r|	InChI=1S/C24H27F5N6/c1-14-9-17-16(3-4-19-18(17)10-30-33-19)22(35(14)13-24(27,28)29)20-5-6-21(23(26)32-20)31-15-11-34(12-15)8-2-7-25/h3-6,10,14-15,22,31H,2,7-9,11-13H2,1H3,(H,30,33)	CRBIBFLRQNHOTI-UHFFFAOYSA-N	300963	2-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)pyridin-3-amine::US10131663, Example 29::US10590130, Example 29::US10961241, Example 29	Potassium voltage-gated channel subfamily H member 2	Human		 27000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300963&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134453532	381749722							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576022	C[C@@H]5Cc1c(ccc2[nH]ncc12)[C@@H](c4ncc(NC3CN(CCCF)C3)cc4F)N5CC(F)(F)F	InChI=1S/C24H27F5N6/c1-14-7-18-17(3-4-21-19(18)10-31-33-21)23(35(14)13-24(27,28)29)22-20(26)8-15(9-30-22)32-16-11-34(12-16)6-2-5-25/h3-4,8-10,14,16,23,32H,2,5-7,11-13H2,1H3,(H,31,33)	HHXTYKXNOKWJQP-UHFFFAOYSA-N	300964	5-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)pyridin-3-amine::US10131663, Example 30::US10590130, Example 30::US10961241, Example 30	Potassium voltage-gated channel subfamily H member 2	Human		>33000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300964&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134459046	381749723							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576023	C[C@@H]5Cc1c(ccc2[nH]ncc12)[C@@H](c4ncc(NC3CN(CCCF)C3)cc4F)N5CC(F)(F)CO	InChI=1S/C25H30F4N6O/c1-15-7-19-18(3-4-22-20(19)10-31-33-22)24(35(15)13-25(28,29)14-36)23-21(27)8-16(9-30-23)32-17-11-34(12-17)6-2-5-26/h3-4,8-10,15,17,24,32,36H,2,5-7,11-14H2,1H3,(H,31,33)	JFHIYLBDXQPCLD-UHFFFAOYSA-N	300965	2,2-Difluoro-3-((6S,8R)-6-(3-fluoro-5-((1-(3-fluoropropyl)azetidin-3-yl)amino)pyridin-2-yl)-8-methyl-3,6,8,9-tetrahydro-7H-pyrazolo[4,3-f]isoquinolin-7-yl)propan-1-ol::US10131663, Example 31::US10590130, Example 31::US10961241, Example 31	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300965&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134459044	381749724							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576024	C[C@@H]5Cc1c(ccc2[nH]nc(F)c12)[C@@H](c4ccc(NC3CN(CCCF)C3)cn4)N5CC(F)(F)F	InChI=1S/C24H27F5N6/c1-14-9-18-17(4-6-19-21(18)23(26)33-32-19)22(35(14)13-24(27,28)29)20-5-3-15(10-30-20)31-16-11-34(12-16)8-2-7-25/h3-6,10,14,16,22,31H,2,7-9,11-13H2,1H3,(H,32,33)	KCGYXBQEIOXRKD-UHFFFAOYSA-N	300966	6-((6S,8R)-1-fluoro-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,9,8-tetrahydro-3H-pyrazolo[4,3-f]isoquin-6-yl)-N-(3-fluoropropyl)azetidi-3-yl)pyridin-3-amine::US10131663, Example 32::US10961241, Example 32	Potassium voltage-gated channel subfamily H member 2	Human		 14000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134459060	381749725							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576025	C[C@@H]5Cc1c(ccc2[nH]nc(F)c12)[C@@H](c4ncc(NC3CN(CCCF)C3)cc4F)N5CC(F)(F)F	InChI=1S/C24H26F6N6/c1-13-7-17-16(3-4-19-20(17)23(27)34-33-19)22(36(13)12-24(28,29)30)21-18(26)8-14(9-31-21)32-15-10-35(11-15)6-2-5-25/h3-4,8-9,13,15,22,32H,2,5-7,10-12H2,1H3,(H,33,34)	XFDBWZWHJOLNAF-UHFFFAOYSA-N	300967	5-Fluoro-6-((6S,8R)-1-fluoro-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-N-(1-(3-fluoropropyl)azetidin-3-yl)pyridin-3-amine::US10131663, Example 33::US10590130, Example 33::US10961241, Example 33	Potassium voltage-gated channel subfamily H member 2	Human		 14000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300967&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134459061	381749726							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576026	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1ccc(cn1)N(C)C1CN(CCCF)C1 |r|	InChI=1S/C25H30F4N6/c1-16-10-20-19(5-7-22-21(20)12-31-32-22)24(35(16)15-25(27,28)29)23-6-4-17(11-30-23)33(2)18-13-34(14-18)9-3-8-26/h4-7,11-12,16,18,24H,3,8-10,13-15H2,1-2H3,(H,31,32)	LWSWCRMTCQGGDJ-UHFFFAOYSA-N	300968	N-(1-(3- fluoropropyl) azetidin-3-yl)- N-methyl-6- ((6S,8R)-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)pyridin-3- amine::US10131663, Example 34::US10590130, Example 34::US10961241, Example 34	Potassium voltage-gated channel subfamily H member 2	Human		 7700							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554006	381749727							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576027	COc1cc(NC2CN(CCCF)C2)cnc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C25H30F4N6O/c1-15-8-19-18(4-5-21-20(19)11-31-33-21)24(35(15)14-25(27,28)29)23-22(36-2)9-16(10-30-23)32-17-12-34(13-17)7-3-6-26/h4-5,9-11,15,17,24,32H,3,6-8,12-14H2,1-2H3,(H,31,33)	KBSGBIFMBKBFMH-UHFFFAOYSA-N	300971	N-(1-(3- fluoropropyl) azetidin-3-yl)-5- methoxy-6- ((6S,8R)-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)pyridin-3- amine::US10131663, Example 37::US10590130, Example 37::US10961241, Example 37	Potassium voltage-gated channel subfamily H member 2	Human		 20000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300971&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554008	381749730							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576028	C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)F)c1cnc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C23H26F5N7/c1-13-7-16-15(3-4-17-20(16)22(25)33-32-17)21(35(13)12-23(26,27)28)18-8-30-19(9-29-18)31-14-10-34(11-14)6-2-5-24/h3-4,8-9,13-14,21H,2,5-7,10-12H2,1H3,(H,30,31)(H,32,33)	ZMANQSXBZZYBCV-UHFFFAOYSA-N	300972	5-((6S,8R)-1- fluoro-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyrazin-2- amine::US10131663, Example 38::US10590130, Example 38::US10961241, Example 38	Potassium voltage-gated channel subfamily H member 2	Human		 18000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554009	381749731							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576029	C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)F)c1ccc(NC2CN(CCCF)C2)c(F)n1 |r|	InChI=1S/C24H26F6N6/c1-13-9-16-15(3-4-17-20(16)23(27)34-33-17)21(36(13)12-24(28,29)30)18-5-6-19(22(26)32-18)31-14-10-35(11-14)8-2-7-25/h3-6,13-14,21,31H,2,7-12H2,1H3,(H,33,34)	KPNMZYDKYZNYIC-UHFFFAOYSA-N	300973	2-fluoro-6- ((6S,8R)-1- fluoro-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 39::US10590130, Example 39::US10961241, Example 39	Potassium voltage-gated channel subfamily H member 2	Human		 14000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300973&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554010	381749732							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576030	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1ccc(NC2CN(CCCF)C2)nc1F |r|	InChI=1S/C24H27F5N6/c1-14-9-18-16(3-5-20-19(18)10-30-33-20)22(35(14)13-24(27,28)29)17-4-6-21(32-23(17)26)31-15-11-34(12-15)8-2-7-25/h3-6,10,14-15,22H,2,7-9,11-13H2,1H3,(H,30,33)(H,31,32)	MOSUHPUFLYLQDT-UHFFFAOYSA-N	300974	6-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-5- ((6S,8R)-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)pyridin-2- amine::US10131663, Example 40::US10590130, Example 40::US10961241, Example 40	Potassium voltage-gated channel subfamily H member 2	Human		 4500							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300974	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300974&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554011	381749733							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576031	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1ccc(NC2CN(CCCF)C2)c(F)c1 |r|	InChI=1S/C25H28F5N5/c1-15-9-19-18(4-6-22-20(19)11-31-33-22)24(35(15)14-25(28,29)30)16-3-5-23(21(27)10-16)32-17-12-34(13-17)8-2-7-26/h3-6,10-11,15,17,24,32H,2,7-9,12-14H2,1H3,(H,31,33)	IYVIYWIRAJCIRW-UHFFFAOYSA-N	300975	N-(2-fluoro-4- ((6R,8R)-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)phenyl)-1- (3- fluoropropyl) azetidin-3- amine::US10131663, Example 41::US10590130, Example 41::US10961241, Example 41	Potassium voltage-gated channel subfamily H member 2	Human		 6500							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300975	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300975&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554012	381749734							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576032	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1cnc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C23H27F4N7/c1-14-7-17-16(3-4-19-18(17)8-30-32-19)22(34(14)13-23(25,26)27)20-9-29-21(10-28-20)31-15-11-33(12-15)6-2-5-24/h3-4,8-10,14-15,22H,2,5-7,11-13H2,1H3,(H,29,31)(H,30,32)	ICIUVKVSEXZBQM-UHFFFAOYSA-N	300976	N-(1-(3- fluoropropyl) azetidin-3-yl)-5- ((6S,8R)-8- methyl-7- (2,2,2- trifluoroethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)pyrazin-2- amine::US10131663, Example 42::US10590130, Example 42::US10961241, Example 42	Potassium voltage-gated channel subfamily H member 2	Human		 7900							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300976	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300976&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554013	381749735							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576033	COc1cc(NC2CN(CCCF)C2)ccc1[C@@]1(C)N(CC(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C27H34F3N5O/c1-17-11-20-21-13-31-33-24(21)8-7-22(20)27(2,35(17)16-26(29)30)23-6-5-18(12-25(23)36-3)32-19-14-34(15-19)10-4-9-28/h5-8,12-13,17,19,26,32H,4,9-11,14-16H2,1-3H3,(H,31,33)	PSBJWNCYYQWCMX-UHFFFAOYSA-N	300979	N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 6,8-dimethyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-3- methoxyphenyl)- 1-(3- fluoropropyl) azetidin-3- amine::US10131663, Example 45::US10590130, Example 45::US10961241, Example 45	Potassium voltage-gated channel subfamily H member 2	Human		 4200							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300979&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554016	381749738							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576034	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)F)c1ncc(NC2CN(CCCF)C2)cc1F |r|	InChI=1S/C24H28F4N6/c1-14-7-18-17(3-4-21-19(18)10-30-32-21)24(34(14)13-22(27)28)23-20(26)8-15(9-29-23)31-16-11-33(12-16)6-2-5-25/h3-4,8-10,14,16,22,24,31H,2,5-7,11-13H2,1H3,(H,30,32)	SADTVAAIAQIVQH-UHFFFAOYSA-N	300980	6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-5-fluoro- N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 46::US10590130, Example 46::US10961241, Example 46	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300980	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300980&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554017	381749739							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576035	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)F)c1c(F)cc(NC2CN(CCCF)C2)cc1F |r|	InChI=1S/C25H28F5N5/c1-14-7-18-17(3-4-22-19(18)10-31-33-22)25(35(14)13-23(29)30)24-20(27)8-15(9-21(24)28)32-16-11-34(12-16)6-2-5-26/h3-4,8-10,14,16,23,25,32H,2,5-7,11-13H2,1H3,(H,31,33)	HJSOKBFUMBEYNW-UHFFFAOYSA-N	300983	N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-3,5- difluorophenyl)- 1-(3- fluoropropyl) azetidin-3- amine::US10131663, Example 49::US10590130, Example 49::US10961241, Example 49	Potassium voltage-gated channel subfamily H member 2	Human		 8200							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300983	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300983&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554020	381749742							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576036	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)F)c1cnc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C23H28F3N7/c1-14-7-17-16(3-4-19-18(17)8-29-31-19)23(33(14)13-21(25)26)20-9-28-22(10-27-20)30-15-11-32(12-15)6-2-5-24/h3-4,8-10,14-15,21,23H,2,5-7,11-13H2,1H3,(H,28,30)(H,29,31)	ICFZXEQTLNSVSO-UHFFFAOYSA-N	300984	5-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyrazin-2- amine::US10131663, Example 50::US10590130, Example 50::US10961241, Example 50	Potassium voltage-gated channel subfamily H member 2	Human		 13000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300984&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554021	381749743							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576037	FCCCN1CC(C1)Nc1ccc(nc1)[C@H]1N(CC(F)F)[C@@H](Cc2c1ccc1[nH]ncc21)C(F)F |r|	InChI=1S/C24H27F5N6/c25-6-1-7-34-11-15(12-34)32-14-2-4-20(30-9-14)23-16-3-5-19-18(10-31-33-19)17(16)8-21(24(28)29)35(23)13-22(26)27/h2-5,9-10,15,21-24,32H,1,6-8,11-13H2,(H,31,33)	FWWHNGKEZAFESY-UHFFFAOYSA-N	300985	6-((6S,8S)-7- (2,2- difluoroethyl)- 8- (difluoromethyl)- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 51::US10590130, Example 51::US10961241, Example 51	Potassium voltage-gated channel subfamily H member 2	Human		 9100							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554022	381749744							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576038	COc1cc(ccc1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1ccc1[nH]ncc21)N(C)C1CN(CCCF)C1 |r|	InChI=1S/C29H37F2N5O/c1-19-13-24-22(7-8-26-25(24)15-32-33-26)28(36(19)18-29(31)9-10-29)23-6-5-20(14-27(23)37-3)34(2)21-16-35(17-21)12-4-11-30/h5-8,14-15,19,21,28H,4,9-13,16-18H2,1-3H3,(H,32,33)	UQMBBZZQYLPVEN-UHFFFAOYSA-N	300986	N-(4-((6S,8R)- 7-((1- fluorocyclo- propyl)methyl)-8- methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-3- methoxyphenyl)- 1-(3- fluoropropyl)- N- methylazetidin- 3-amine::US10131663, Example 52::US10590130, Example 52::US10961241, Example 52	Potassium voltage-gated channel subfamily H member 2	Human		 2000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300986	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300986&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554023	381749745							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576039	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1cnc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H31F2N7/c1-16-9-19-18(3-4-21-20(19)10-30-32-21)24(34(16)15-25(27)5-6-25)22-11-29-23(12-28-22)31-17-13-33(14-17)8-2-7-26/h3-4,10-12,16-17,24H,2,5-9,13-15H2,1H3,(H,29,31)(H,30,32)	YUMXUYVBLHCRQN-UHFFFAOYSA-N	300989	5-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyrazin-2- amine::US10131663, Example 55::US10590130, Example 55::US10961241, Example 55	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300989&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554026	381749748							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576040	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1ccc(cn1)N(C)C1CN(CCCF)C1 |r|	InChI=1S/C27H34F2N6/c1-18-12-22-21(5-7-24-23(22)14-31-32-24)26(35(18)17-27(29)8-9-27)25-6-4-19(13-30-25)33(2)20-15-34(16-20)11-3-10-28/h4-7,13-14,18,20,26H,3,8-12,15-17H2,1-2H3,(H,31,32)	AMZHEQZGCLSTMF-UHFFFAOYSA-N	300991	6-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4 3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3-yl)- N- methylpyridin- 3-amine::US10131663, Example 57::US10590130, Example 57::US10961241, Example 57	Potassium voltage-gated channel subfamily H member 2	Human		 16000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554028	381749750							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576041	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)CO)c1ccc(OC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H30F3N5O2/c1-16-9-20-19(4-6-22-21(20)11-30-31-22)24(33(16)14-25(27,28)15-34)23-5-3-17(10-29-23)35-18-12-32(13-18)8-2-7-26/h3-6,10-11,16,18,24,34H,2,7-9,12-15H2,1H3,(H,30,31)	JXLYITXDNWJUQB-UHFFFAOYSA-N	300992	2,2-difluoro-3- ((6S,8R)-6-(5- ((1-(3- fluoropropyl) azetidin-3- yl)oxy)pyridin- 2-yl)-8- methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol::US10131663, Example 58::US10590130, Example 58::US10961241, Example 58	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300992&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554029	381749751							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576042	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)CO)c1ncc(OC2CN(CCCF)C2)cc1F |r|	InChI=1S/C25H29F4N5O2/c1-15-7-19-18(3-4-22-20(19)10-31-32-22)24(34(15)13-25(28,29)14-35)23-21(27)8-16(9-30-23)36-17-11-33(12-17)6-2-5-26/h3-4,8-10,15,17,24,35H,2,5-7,11-14H2,1H3,(H,31,32)	CYBJAJOVKOECGI-UHFFFAOYSA-N	300993	2,2-difluoro-3- ((6S,8R)-6-(3- fluoro-5-((1- (3- fluoropropyl) azetidin-3- yl)oxy)pyridin- 2-yl)-8- methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol::US10131663, Example 59::US10590130, Example 59::US10961241, Example 59	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300993&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554030	381749752							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576043	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C27H34F3N5O2/c1-17-10-22-20(6-7-24-23(22)12-31-33-24)26(35(17)15-27(29,30)16-36)21-5-4-18(11-25(21)37-2)32-19-13-34(14-19)9-3-8-28/h4-7,11-12,17,19,26,32,36H,3,8-10,13-16H2,1-2H3,(H,31,33)	FAPHIOPFHPLRGC-UHFFFAOYSA-N	300994	2,2-difluoro-3- ((6S,8R)-6-(4- ((1-(3- fluoropropyl) azetidin-3- yl)amino)-2- methoxyphenyl)- 8-methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol::US10131663, Example 60::US10961241, Example 60	Potassium voltage-gated channel subfamily H member 2	Human		 11000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554031	381749753							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576044	C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)CO)c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H30F4N6O/c1-15-9-19-18(4-6-20-22(19)24(27)33-32-20)23(35(15)13-25(28,29)14-36)21-5-3-16(10-30-21)31-17-11-34(12-17)8-2-7-26/h3-6,10,15,17,23,31,36H,2,7-9,11-14H2,1H3,(H,32,33)	WLCJMJDIOQYAKD-UHFFFAOYSA-N	300995	2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(5- ((1-(3- fluoropropyl) azetidin-3- yl)amino)pyridin- 2-yl)-8- methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol::US10131663, Example 61::US10961241, Example 61	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300995&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554032	381749754							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576045	C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)CO)c1ccc(NC2CN(CCCF)C2)c(F)n1 |r|	InChI=1S/C25H29F5N6O/c1-14-9-17-16(3-4-18-21(17)24(28)34-33-18)22(36(14)12-25(29,30)13-37)19-5-6-20(23(27)32-19)31-15-10-35(11-15)8-2-7-26/h3-6,14-15,22,31,37H,2,7-13H2,1H3,(H,33,34)	YMJIAMCWLDWKKQ-UHFFFAOYSA-N	300996	2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(6- fluoro-5-((1- (3- fluoropropyl) azetidin-3- yl)amino)pyridin- 2-yl)-8- methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol::US10131663, Example 62::US10590130, Example 62::US10961241, Example 62	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300996&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554033	381749755							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576046	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(C)F)c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C26H34F2N6/c1-17-11-21-20(6-8-23-22(21)13-30-32-23)25(34(17)16-26(2,3)28)24-7-5-18(12-29-24)31-19-14-33(15-19)10-4-9-27/h5-8,12-13,17,19,25,31H,4,9-11,14-16H2,1-3H3,(H,30,32)	RMHSPVDIAHEXNT-UHFFFAOYSA-N	300997	6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 63::US10590130, Example 70::US10961241, Example 63	Potassium voltage-gated channel subfamily H member 2	Human		 13000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300997&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554034	381749756							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576047	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(C)(C)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C28H37F2N5O/c1-18-12-23-21(8-9-25-24(23)14-31-33-25)27(35(18)17-28(2,3)30)22-7-6-19(13-26(22)36-4)32-20-15-34(16-20)11-5-10-29/h6-9,13-14,18,20,27,32H,5,10-12,15-17H2,1-4H3,(H,31,33)	LXPLSZAVQYCVGQ-UHFFFAOYSA-N	300998	N-(4-((6S,8R)- 7-(2-fluoro-2- methylpropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-3- methoxyphenyl)- 1-(3- fluoropropyl) azetidin-3- amine::US10131663, Example 64::US10590130, Example 64::US10961241, Example 64	Potassium voltage-gated channel subfamily H member 2	Human		 13000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300998&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554035	381749757							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576048	CC(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H32F2N6/c1-16(27)13-33-17(2)10-21-20(5-7-23-22(21)12-29-31-23)25(33)24-6-4-18(11-28-24)30-19-14-32(15-19)9-3-8-26/h4-7,11-12,16-17,19,25,30H,3,8-10,13-15H2,1-2H3,(H,29,31)	PQZGPKXZUSHGLE-UHFFFAOYSA-N	300999	US10131663, Example 66::6-((6S,8R)-7- (2- fluoropropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 65::US10590130, Example 66::US10961241, Example 66	Potassium voltage-gated channel subfamily H member 2	Human		 31000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300999&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554036	381749758							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576049	CC(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H32F2N6/c1-16(27)13-33-17(2)10-21-20(5-7-23-22(21)12-29-31-23)25(33)24-6-4-18(11-28-24)30-19-14-32(15-19)9-3-8-26/h4-7,11-12,16-17,19,25,30H,3,8-10,13-15H2,1-2H3,(H,29,31)	PQZGPKXZUSHGLE-UHFFFAOYSA-N	300999	US10131663, Example 66::6-((6S,8R)-7- (2- fluoropropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 65::US10590130, Example 66::US10961241, Example 66	Potassium voltage-gated channel subfamily H member 2	Human		 26000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=300999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=300999&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554036	381749758							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576050	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(C)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C27H35F2N5O/c1-17(29)14-34-18(2)11-23-21(7-8-25-24(23)13-30-32-25)27(34)22-6-5-19(12-26(22)35-3)31-20-15-33(16-20)10-4-9-28/h5-8,12-13,17-18,20,27,31H,4,9-11,14-16H2,1-3H3,(H,30,32)	QVUDEDBAGYAVHI-UHFFFAOYSA-N	301001	US10131663, Example 67::BDBM301002::1-(3- fluoropropyl)- N-(4-((6S,8R)- 7-(2- fluoropropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-3- methoxyphenyl) azetidin-3- amine::US10590130, Example 68::US10961241, Example 68	Potassium voltage-gated channel subfamily H member 2	Human		 14000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=301001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=301001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554037	381749759							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576051	COc1cc(NC2CN(CCCF)C2)ccc1[C@H]1N(CC(C)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C27H35F2N5O/c1-17(29)14-34-18(2)11-23-21(7-8-25-24(23)13-30-32-25)27(34)22-6-5-19(12-26(22)35-3)31-20-15-33(16-20)10-4-9-28/h5-8,12-13,17-18,20,27,31H,4,9-11,14-16H2,1-3H3,(H,30,32)	QVUDEDBAGYAVHI-UHFFFAOYSA-N	301001	US10131663, Example 67::BDBM301002::1-(3- fluoropropyl)- N-(4-((6S,8R)- 7-(2- fluoropropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-3- methoxyphenyl) azetidin-3- amine::US10590130, Example 68::US10961241, Example 68	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=301001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=301001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554037	381749759							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576052	CC(C)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C26H35FN6/c1-17(2)14-33-18(3)11-22-21(6-8-24-23(22)13-29-31-24)26(33)25-7-5-19(12-28-25)30-20-15-32(16-20)10-4-9-27/h5-8,12-13,17-18,20,26,30H,4,9-11,14-16H2,1-3H3,(H,29,31)	VQGLUTISKQTZKB-UHFFFAOYSA-N	301003	N-(1-(3- fluoropropyl) azetidin-3-yl)-6-  ((6S,8R)-7- isobutyl-8- methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)pyridin-3- amine::US10131663, Example 69::US10590130, Example 69::US10961241, Example 69	Potassium voltage-gated channel subfamily H member 2	Human		 24000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=301003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=301003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554038	381749761							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576053	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(F)F)c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H31F3N6/c1-16-10-20-19(5-7-22-21(20)12-30-32-22)24(34(16)15-25(2,27)28)23-6-4-17(11-29-23)31-18-13-33(14-18)9-3-8-26/h4-7,11-12,16,18,24,31H,3,8-10,13-15H2,1-2H3,(H,30,32)	YJZXOHCPDWISMV-UHFFFAOYSA-N	301004	6-((6S,8R)-7- (2,2- difluoropropyl)- 8-methyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 70::US10961241, Example 70	Potassium voltage-gated channel subfamily H member 2	Human		 24000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=301004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=301004&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554039	381749762							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
576054	CC1(C)Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)F)c1ccc(NC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H31F3N6/c1-25(2)10-19-18(5-7-21-20(19)12-30-32-21)24(34(25)15-23(27)28)22-6-4-16(11-29-22)31-17-13-33(14-17)9-3-8-26/h4-7,11-12,17,23-24,31H,3,8-10,13-15H2,1-2H3,(H,30,32)	NNKIFQRRDDJHKS-UHFFFAOYSA-N	301007	(S)-6-(7-(2,2- difluoroethyl)- 8,8-dimethyl- 6,7,8,9- tetrahydro-3H- pyrazolo[4,3- f]isoquinolin- 6-yl)-N-(1-(3- fluoropropyl) azetidin-3- yl)pyridin-3- amine::US10131663, Example 73::US10590130, Example 73::US10961241, Example 73	Potassium voltage-gated channel subfamily H member 2	Human		 12000							US Patent		10.7270/Q2P55QJ9		aid1796073	US10131663	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	11/20/2018	3/29/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=301007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=301007&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137554042	381749765							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597940	Cc1n[nH]c(C)c1CCn1cc(cn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C17H17ClF2N4O/c1-10-14(11(2)23-22-10)5-6-24-9-13(8-21-24)12-3-4-15(18)16(7-12)25-17(19)20/h3-4,7-9,17H,5-6H2,1-2H3,(H,22,23)	CRTYJRKVIQBRIW-UHFFFAOYSA-N	310948	US10155727, Example 1::USRE49517, Example 1	Potassium voltage-gated channel subfamily H member 2	Human		 65.5							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310948	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310948&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864225	382366816							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597941	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C15H13ClF2N4O/c1-21-5-4-12(20-21)9-22-8-11(7-19-22)10-2-3-13(16)14(6-10)23-15(17)18/h2-8,15H,9H2,1H3	CRYKKCVVHRIZJU-UHFFFAOYSA-N	50201021	CHEMBL3966599::US10155727, Example 2::USRE49517, Example 2	Potassium voltage-gated channel subfamily H member 2	Human		 78.4							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864285	375979239		CHEMBL3966599					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597942	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n(C)n1	InChI=1S/C16H15ClF2N4O/c1-10-5-13(22(2)21-10)9-23-8-12(7-20-23)11-3-4-14(17)15(6-11)24-16(18)19/h3-8,16H,9H2,1-2H3	ZCZZFZFZUWEHRG-UHFFFAOYSA-N	310950	US10155727, Example 3::USRE49517, Example 3	Potassium voltage-gated channel subfamily H member 2	Human		 146							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310950&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864190	382366818							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597943	Cn1cc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)cn1	InChI=1S/C15H13ClF2N4O/c1-21-7-10(5-19-21)8-22-9-12(6-20-22)11-2-3-13(16)14(4-11)23-15(17)18/h2-7,9,15H,8H2,1H3	TYWLMLPPMXWFPX-UHFFFAOYSA-N	50201024	CHEMBL3936854::US10155727, Example 4::USRE49517, Example 4	Potassium voltage-gated channel subfamily H member 2	Human		 119							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201024&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864476	375979242		CHEMBL3936854					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597944	Cn1nccc1Cn1cc(cn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H13ClF2N4O/c1-21-12(4-5-19-21)9-22-8-11(7-20-22)10-2-3-13(16)14(6-10)23-15(17)18/h2-8,15H,9H2,1H3	BHOUUDZNGWHFHC-UHFFFAOYSA-N	310952	US10155727, Example 5::USRE49517, Example 5	Potassium voltage-gated channel subfamily H member 2	Human		 148							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310952	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310952&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864176	382366820							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597945	FC(F)Oc1cc(ccc1Cl)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11ClF2N4O/c15-12-2-1-9(5-13(12)22-14(16)17)10-6-19-21(7-10)8-11-3-4-18-20-11/h1-7,14H,8H2,(H,18,20)	WXIFVEVHNGMUHP-UHFFFAOYSA-N	50201022	CHEMBL3897632::US10155727, Example 6::USRE49517, Example 6	Potassium voltage-gated channel subfamily H member 2	Human		 5.21							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201022&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864437	375979240		CHEMBL3897632					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597946	FC(F)Oc1cc(ccc1Cl)-c1cnn(Cc2cn[nH]c2)c1	InChI=1S/C14H11ClF2N4O/c15-12-2-1-10(3-13(12)22-14(16)17)11-6-20-21(8-11)7-9-4-18-19-5-9/h1-6,8,14H,7H2,(H,18,19)	WQIJWPZIOIFLHO-UHFFFAOYSA-N	50201023	CHEMBL3927856::US10155727, Example 7::USRE49517, Example 7	Potassium voltage-gated channel subfamily H member 2	Human		 8.23							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201023	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201023&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864482	375979241		CHEMBL3927856					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597947	CCn1ccc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C16H15ClF2N4O/c1-2-22-6-5-13(21-22)10-23-9-12(8-20-23)11-3-4-14(17)15(7-11)24-16(18)19/h3-9,16H,2,10H2,1H3	PCHBMVPVCPSMLD-UHFFFAOYSA-N	310955	US10155727, Example 8::USRE49517, Example 8	Potassium voltage-gated channel subfamily H member 2	Human		 281							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310955	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310955&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864364	382366823							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597948	FC(F)Oc1cc(ccc1Cl)-c1cnn(CCc2cn[nH]c2)c1	InChI=1S/C15H13ClF2N4O/c16-13-2-1-11(5-14(13)23-15(17)18)12-8-21-22(9-12)4-3-10-6-19-20-7-10/h1-2,5-9,15H,3-4H2,(H,19,20)	OGSQOKYLXLIXRK-UHFFFAOYSA-N	310956	US10155727, Example 9::USRE49517, Example 9	Potassium voltage-gated channel subfamily H member 2	Human		 152							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310956&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796692	382366824							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597949	CCn1cc(CCn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)cn1	InChI=1S/C17H17ClF2N4O/c1-2-23-10-12(8-21-23)5-6-24-11-14(9-22-24)13-3-4-15(18)16(7-13)25-17(19)20/h3-4,7-11,17H,2,5-6H2,1H3	WXLDTHJZQFCOMH-UHFFFAOYSA-N	310957	US10155727, Example 10::USRE49517, Example 10	Potassium voltage-gated channel subfamily H member 2	Human		 250							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864201	382366825							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597950	CCC(CC)n1ccc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n1	InChI=1S/C19H21ClF2N4O/c1-3-16(4-2)26-8-7-15(24-26)12-25-11-14(10-23-25)13-5-6-17(20)18(9-13)27-19(21)22/h5-11,16,19H,3-4,12H2,1-2H3	VCIYUUWUQVIFEO-UHFFFAOYSA-N	311039	US10155727, Example 11::USRE49517, Example 11	Potassium voltage-gated channel subfamily H member 2	Human		>1000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864416	382366907							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597951	FC(F)Oc1cc(ccc1Cl)-c1cnn(Cc2ccn(n2)C2CCCC2)c1	InChI=1S/C19H19ClF2N4O/c20-17-6-5-13(9-18(17)27-19(21)22)14-10-23-25(11-14)12-15-7-8-26(24-15)16-3-1-2-4-16/h5-11,16,19H,1-4,12H2	LRTTWINCSMBJMM-UHFFFAOYSA-N	310958	US10155727, Example 12::USRE49517, Example 12	Potassium voltage-gated channel subfamily H member 2	Human		 280							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310958	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310958&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864386	382366826							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597952	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)[nH]n1	InChI=1S/C15H13ClF2N4O/c1-9-4-12(21-20-9)8-22-7-11(6-19-22)10-2-3-13(16)14(5-10)23-15(17)18/h2-7,15H,8H2,1H3,(H,20,21)	RNBFGQKOKMISQP-UHFFFAOYSA-N	310959	US10155727, Example 13::USRE49517, Example 13	Potassium voltage-gated channel subfamily H member 2	Human		 22.1							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864401	382366827							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597953	CCc1cc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n[nH]1	InChI=1S/C16H15ClF2N4O/c1-2-12-6-13(22-21-12)9-23-8-11(7-20-23)10-3-4-14(17)15(5-10)24-16(18)19/h3-8,16H,2,9H2,1H3,(H,21,22)	PTYPZHOITALPCT-UHFFFAOYSA-N	310960	US10155727, Example 14::USRE49517, Example 14	Potassium voltage-gated channel subfamily H member 2	Human		 76.2							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310960&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796693	382366828							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597954	CCCc1cc(Cn2cc(cn2)-c2ccc(Cl)c(OC(F)F)c2)n[nH]1	InChI=1S/C17H17ClF2N4O/c1-2-3-13-7-14(23-22-13)10-24-9-12(8-21-24)11-4-5-15(18)16(6-11)25-17(19)20/h4-9,17H,2-3,10H2,1H3,(H,22,23)	BQEMIVBQABRGAT-UHFFFAOYSA-N	310961	US10155727, Example 15::USRE49517, Example 15	Potassium voltage-gated channel subfamily H member 2	Human		 163							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796694	382366829							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597955	Cc1[nH]ncc1Cn1cc(cn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H13ClF2N4O/c1-9-11(5-19-21-9)7-22-8-12(6-20-22)10-2-3-13(16)14(4-10)23-15(17)18/h2-6,8,15H,7H2,1H3,(H,19,21)	PLNFUYPBLOEXJI-UHFFFAOYSA-N	310962	US10155727, Example 16::USRE49517, Example 16	Potassium voltage-gated channel subfamily H member 2	Human		 41.1							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310962&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796695	382366830							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597956	CCc1[nH]ncc1Cn1cc(cn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H15ClF2N4O/c1-2-14-12(6-20-22-14)9-23-8-11(7-21-23)10-3-4-13(17)15(5-10)24-16(18)19/h3-8,16H,2,9H2,1H3,(H,20,22)	IZRNPSABLKZTLN-UHFFFAOYSA-N	50201026	CHEMBL3983077::US10155727, Example 17::USRE49517, Example 17	Potassium voltage-gated channel subfamily H member 2	Human		 56.0							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201026&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864208	375979244		CHEMBL3983077					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597957	FC(F)Oc1cc(ccc1F)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11F3N4O/c15-12-2-1-9(5-13(12)22-14(16)17)10-6-19-21(7-10)8-11-3-4-18-20-11/h1-7,14H,8H2,(H,18,20)	LHMLJRCNGQZNHL-UHFFFAOYSA-N	50201028	CHEMBL3954438::US10155727, Example 18::USRE49517, Example 18	Potassium voltage-gated channel subfamily H member 2	Human		 8.01							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201028&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864337	375979246		CHEMBL3954438					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597958	Cn1cc(Cn2cc(cn2)-c2ccc(F)c(OC(F)F)c2)cn1	InChI=1S/C15H13F3N4O/c1-21-7-10(5-19-21)8-22-9-12(6-20-22)11-2-3-13(16)14(4-11)23-15(17)18/h2-7,9,15H,8H2,1H3	WTJLEJBVIDJMFC-UHFFFAOYSA-N	310965	US10155727, Example 19::USRE49517, Example 19	Potassium voltage-gated channel subfamily H member 2	Human		 202							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310965&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864400	382366833							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597959	CCc1[nH]ncc1Cn1cc(cn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C16H15F3N4O/c1-2-14-12(6-20-22-14)9-23-8-11(7-21-23)10-3-4-13(17)15(5-10)24-16(18)19/h3-8,16H,2,9H2,1H3,(H,20,22)	IGIJOLSYMZJTQD-UHFFFAOYSA-N	310966	US10155727, Example 20::USRE49517, Example 20	Potassium voltage-gated channel subfamily H member 2	Human		 22.2							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118884493	382366834							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597960	FC(F)Oc1cc(Cl)cc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11ClF2N4O/c15-11-3-9(4-13(5-11)22-14(16)17)10-6-19-21(7-10)8-12-1-2-18-20-12/h1-7,14H,8H2,(H,18,20)	FDBPKEPRZDXSQA-UHFFFAOYSA-N	310967	US10155727, Example 21::USRE49517, Example 21	Potassium voltage-gated channel subfamily H member 2	Human		 1021							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310967&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864275	382366835							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597961	Cc1cc(Cn2cc(cn2)-c2cccc(OC(F)(F)F)c2)n(C)n1	InChI=1S/C16H15F3N4O/c1-11-6-14(22(2)21-11)10-23-9-13(8-20-23)12-4-3-5-15(7-12)24-16(17,18)19/h3-9H,10H2,1-2H3	IOTYDSRQXWYEOM-UHFFFAOYSA-N	310968	US10155727, Example 22::USRE49517, Example 22	Potassium voltage-gated channel subfamily H member 2	Human		 2760							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864288	382366836							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597962	Cn1ccc(Cn2cc(cn2)-c2cccc(OC(F)(F)F)c2)n1	InChI=1S/C15H13F3N4O/c1-21-6-5-13(20-21)10-22-9-12(8-19-22)11-3-2-4-14(7-11)23-15(16,17)18/h2-9H,10H2,1H3	CPBUZCHPDATVEU-UHFFFAOYSA-N	310969	US10155727, Example 23::USRE49517, Example 23	Potassium voltage-gated channel subfamily H member 2	Human		 1590							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310969	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310969&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864260	382366837							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597963	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)c(c2)C(F)F)n1	InChI=1S/C15H13ClF2N4/c1-21-5-4-12(20-21)9-22-8-11(7-19-22)10-2-3-14(16)13(6-10)15(17)18/h2-8,15H,9H2,1H3	LVYDQZJCZSJMBO-UHFFFAOYSA-N	310970	US10155727, Example 24::USRE49517, Example 24	Potassium voltage-gated channel subfamily H member 2	Human		 410							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310970&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864339	382366838							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597964	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(c2)C(F)F)n(C)n1	InChI=1S/C16H15ClF2N4/c1-10-5-13(22(2)21-10)9-23-8-12(7-20-23)11-3-4-15(17)14(6-11)16(18)19/h3-8,16H,9H2,1-2H3	RTURIZKUGANKMN-UHFFFAOYSA-N	310971	US10155727, Example 25::USRE49517, Example 25	Potassium voltage-gated channel subfamily H member 2	Human		 980							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310971&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864153	382366839							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597965	FC(F)c1cc(ccc1Cl)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11ClF2N4/c15-13-2-1-9(5-12(13)14(16)17)10-6-19-21(7-10)8-11-3-4-18-20-11/h1-7,14H,8H2,(H,18,20)	GPZNPXAPAFLRLB-UHFFFAOYSA-N	50201025	CHEMBL3975087::US10155727, Example 26::USRE49517, Example 26	Potassium voltage-gated channel subfamily H member 2	Human		 30.1							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201025&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864313	375979243		CHEMBL3975087					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597966	Cc1n[nH]c(C)c1CCn1cc(cn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C17H17ClF2N4/c1-10-14(11(2)23-22-10)5-6-24-9-13(8-21-24)12-3-4-16(18)15(7-12)17(19)20/h3-4,7-9,17H,5-6H2,1-2H3,(H,22,23)	FMPLJMMZEDLVOK-UHFFFAOYSA-N	310973	US10155727, Example 27::USRE49517, Example 27	Potassium voltage-gated channel subfamily H member 2	Human		 7170							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310973	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310973&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796696	382366841							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597967	FC(F)c1cc(Cl)cc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11ClF2N4/c15-12-4-9(3-10(5-12)14(16)17)11-6-19-21(7-11)8-13-1-2-18-20-13/h1-7,14H,8H2,(H,18,20)	XXULOVVPELJMEY-UHFFFAOYSA-N	310974	US10155727, Example 28::USRE49517, Example 28	Potassium voltage-gated channel subfamily H member 2	Human		 638							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310974	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310974&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796697	382366842							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597968	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(c2)C(F)(F)F)n(C)n1	InChI=1S/C16H14ClF3N4/c1-10-5-13(23(2)22-10)9-24-8-12(7-21-24)11-3-4-15(17)14(6-11)16(18,19)20/h3-8H,9H2,1-2H3	CJTATZNAJJRQJR-UHFFFAOYSA-N	310975	US10155727, Example 29::USRE49517, Example 29	Potassium voltage-gated channel subfamily H member 2	Human		 2540							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310975	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310975&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864212	382366843							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597969	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)c(c2)C(F)(F)F)n1	InChI=1S/C15H12ClF3N4/c1-22-5-4-12(21-22)9-23-8-11(7-20-23)10-2-3-14(16)13(6-10)15(17,18)19/h2-8H,9H2,1H3	FDYFJXNCCIBNPD-UHFFFAOYSA-N	50201027	CHEMBL3945735::US10155727, Example 30::USRE49517, Example 30	Potassium voltage-gated channel subfamily H member 2	Human		 1010							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864419	375979245		CHEMBL3945735					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597970	Cn1ccc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C15H13F3N4/c1-21-5-4-12(20-21)9-22-8-11(7-19-22)10-2-3-14(16)13(6-10)15(17)18/h2-8,15H,9H2,1H3	POUMWMHGHUZSLS-UHFFFAOYSA-N	310977	US10155727, Example 31::USRE49517, Example 31	Potassium voltage-gated channel subfamily H member 2	Human		 264							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310977	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310977&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864335	382366845							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597971	Cc1cc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)n(C)n1	InChI=1S/C16H15F3N4/c1-10-5-13(22(2)21-10)9-23-8-12(7-20-23)11-3-4-15(17)14(6-11)16(18)19/h3-8,16H,9H2,1-2H3	SOTBKNXFRAXTAE-UHFFFAOYSA-N	310978	US10155727, Example 32::USRE49517, Example 32	Potassium voltage-gated channel subfamily H member 2	Human		 323							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310978	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310978&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864263	382366846							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597972	Cn1cc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)cn1	InChI=1S/C15H13F3N4/c1-21-7-10(5-19-21)8-22-9-12(6-20-22)11-2-3-14(16)13(4-11)15(17)18/h2-7,9,15H,8H2,1H3	DOQIJLDPMKRTSR-UHFFFAOYSA-N	310979	US10155727, Example 33::USRE49517, Example 33	Potassium voltage-gated channel subfamily H member 2	Human		 371							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310979&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864418	382366847							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597973	Cn1nccc1Cn1cc(cn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C15H13F3N4/c1-21-12(4-5-19-21)9-22-8-11(7-20-22)10-2-3-14(16)13(6-10)15(17)18/h2-8,15H,9H2,1H3	QWQROZAMNURWBT-UHFFFAOYSA-N	310980	US10155727, Example 34::USRE49517, Example 34	Potassium voltage-gated channel subfamily H member 2	Human		 866							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310980	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310980&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864199	382366848							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597974	FC(F)c1cc(ccc1F)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11F3N4/c15-13-2-1-9(5-12(13)14(16)17)10-6-19-21(7-10)8-11-3-4-18-20-11/h1-7,14H,8H2,(H,18,20)	SBFDBMKEWKLRSB-UHFFFAOYSA-N	310981	US10155727, Example 35::USRE49517, Example 35	Potassium voltage-gated channel subfamily H member 2	Human		 17.6							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310981	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310981&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864417	382366849							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597975	Cc1n[nH]c(C)c1CCn1cc(cn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C17H17F3N4/c1-10-14(11(2)23-22-10)5-6-24-9-13(8-21-24)12-3-4-16(18)15(7-12)17(19)20/h3-4,7-9,17H,5-6H2,1-2H3,(H,22,23)	SKQPTLPPMSYEQN-UHFFFAOYSA-N	310982	US10155727, Example 36::USRE49517, Example 36	Potassium voltage-gated channel subfamily H member 2	Human		 424							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310982&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864411	382366850							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597976	FC(F)c1cc(ccc1F)-c1cnn(CCc2cn[nH]c2)c1	InChI=1S/C15H13F3N4/c16-14-2-1-11(5-13(14)15(17)18)12-8-21-22(9-12)4-3-10-6-19-20-7-10/h1-2,5-9,15H,3-4H2,(H,19,20)	JPDCMOOBLLIEFK-UHFFFAOYSA-N	310983	US10155727, Example 37::USRE49517, Example 37	Potassium voltage-gated channel subfamily H member 2	Human		 2060							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310983	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310983&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864450	382366851							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597977	CCn1ccc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)n1	InChI=1S/C16H15F3N4/c1-2-22-6-5-13(21-22)10-23-9-12(8-20-23)11-3-4-15(17)14(7-11)16(18)19/h3-9,16H,2,10H2,1H3	GBHOKNOTTNNQTQ-UHFFFAOYSA-N	310984	US10155727, Example 38::USRE49517, Example 38	Potassium voltage-gated channel subfamily H member 2	Human		 443							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310984&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864252	382366852							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597978	Cc1cc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)[nH]n1	InChI=1S/C15H13F3N4/c1-9-4-12(21-20-9)8-22-7-11(6-19-22)10-2-3-14(16)13(5-10)15(17)18/h2-7,15H,8H2,1H3,(H,20,21)	MACPRACNPYALGP-UHFFFAOYSA-N	310985	US10155727, Example 39::USRE49517, Example 39	Potassium voltage-gated channel subfamily H member 2	Human		 102							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864388	382366853							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597979	CCc1cc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)n[nH]1	InChI=1S/C16H15F3N4/c1-2-12-6-13(22-21-12)9-23-8-11(7-20-23)10-3-4-15(17)14(5-10)16(18)19/h3-8,16H,2,9H2,1H3,(H,21,22)	IDFCRAJKFUCDED-UHFFFAOYSA-N	310986	US10155727, Example 40::USRE49517, Example 40	Potassium voltage-gated channel subfamily H member 2	Human		 47.0							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310986	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310986&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864296	382366854							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597980	CCCc1cc(Cn2cc(cn2)-c2ccc(F)c(c2)C(F)F)n[nH]1	InChI=1S/C17H17F3N4/c1-2-3-13-7-14(23-22-13)10-24-9-12(8-21-24)11-4-5-16(18)15(6-11)17(19)20/h4-9,17H,2-3,10H2,1H3,(H,22,23)	RQYYUIGRZDLILP-UHFFFAOYSA-N	310987	US10155727, Example 41::USRE49517, Example 41	Potassium voltage-gated channel subfamily H member 2	Human		 114							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864287	382366855							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597981	Cc1[nH]ncc1Cn1cc(cn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C15H13F3N4/c1-9-11(5-19-21-9)7-22-8-12(6-20-22)10-2-3-14(16)13(4-10)15(17)18/h2-6,8,15H,7H2,1H3,(H,19,21)	DFRNAZVJXDTBSV-UHFFFAOYSA-N	310988	US10155727, Example 42::USRE49517, Example 42	Potassium voltage-gated channel subfamily H member 2	Human		 202							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310988	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310988&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864342	382366856							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597982	CCc1[nH]ncc1Cn1cc(cn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H15F3N4/c1-2-15-12(6-20-22-15)9-23-8-11(7-21-23)10-3-4-14(17)13(5-10)16(18)19/h3-8,16H,2,9H2,1H3,(H,20,22)	WJDFZNSBELJCKM-UHFFFAOYSA-N	310989	US10155727, Example 43::USRE49517, Example 43	Potassium voltage-gated channel subfamily H member 2	Human		 134							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310989	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310989&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864473	382366857							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597983	CC(F)(F)c1cc(ccc1F)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C15H13F3N4/c1-15(17,18)13-6-10(2-3-14(13)16)11-7-20-22(8-11)9-12-4-5-19-21-12/h2-8H,9H2,1H3,(H,19,21)	RQQJZPUPHSLLRR-UHFFFAOYSA-N	310990	US10155727, Example 44::USRE49517, Example 44	Potassium voltage-gated channel subfamily H member 2	Human		 17.1							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310990&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864198	382366858							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597984	Cn1cc(Cn2cc(cn2)-c2ccc(F)c(c2)C(C)(F)F)cn1	InChI=1S/C16H15F3N4/c1-16(18,19)14-5-12(3-4-15(14)17)13-7-21-23(10-13)9-11-6-20-22(2)8-11/h3-8,10H,9H2,1-2H3	DDNUGAKPXYMUKR-UHFFFAOYSA-N	310991	US10155727, Example 45::USRE49517, Example 45	Potassium voltage-gated channel subfamily H member 2	Human		 261							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864282	382366859							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597985	CCc1[nH]ncc1Cn1cc(cn1)-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C17H17F3N4/c1-3-16-13(7-21-23-16)10-24-9-12(8-22-24)11-4-5-15(18)14(6-11)17(2,19)20/h4-9H,3,10H2,1-2H3,(H,21,23)	MVGNHQREGRFEQQ-UHFFFAOYSA-N	310992	US10155727, Example 46::USRE49517, Example 46	Potassium voltage-gated channel subfamily H member 2	Human		 106							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310992&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864329	382366860							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597986	FC(F)c1cc(F)cc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H11F3N4/c15-12-4-9(3-10(5-12)14(16)17)11-6-19-21(7-11)8-13-1-2-18-20-13/h1-7,14H,8H2,(H,18,20)	RYCVRENONIWUPU-UHFFFAOYSA-N	310993	US10155727, Example 47::USRE49517, Example 47	Potassium voltage-gated channel subfamily H member 2	Human		 203							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310993&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796698	382366861							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597987	Cc1cc(Cn2cc(cn2)-c2cccc(c2)C(F)(F)F)n(C)n1	InChI=1S/C16H15F3N4/c1-11-6-15(22(2)21-11)10-23-9-13(8-20-23)12-4-3-5-14(7-12)16(17,18)19/h3-9H,10H2,1-2H3	CJDZRSVYGKAPJM-UHFFFAOYSA-N	310994	US10155727, Example 48::USRE49517, Example 48	Potassium voltage-gated channel subfamily H member 2	Human		 1970							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864240	382366862							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597988	Cn1ccc(Cn2cc(cn2)-c2cccc(c2)C(F)(F)F)n1	InChI=1S/C15H13F3N4/c1-21-6-5-14(20-21)10-22-9-12(8-19-22)11-3-2-4-13(7-11)15(16,17)18/h2-9H,10H2,1H3	NHIDZRFOLGDIRM-UHFFFAOYSA-N	310995	US10155727, Example 49::USRE49517, Example 49	Potassium voltage-gated channel subfamily H member 2	Human		 2250							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310995	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310995&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796699	382366863							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597989	Cn1ccc(Cn2cc(cn2)-c2ccc(cc2)C(F)(F)F)n1	InChI=1S/C15H13F3N4/c1-21-7-6-14(20-21)10-22-9-12(8-19-22)11-2-4-13(5-3-11)15(16,17)18/h2-9H,10H2,1H3	XOPZVFQOFXIGRI-UHFFFAOYSA-N	310996	US10155727, Example 50::USRE49517, Example 50	Potassium voltage-gated channel subfamily H member 2	Human		 4250							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310996	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310996&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864222	382366864							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597990	Cc1cc(Cn2cc(cn2)-c2ccc(cc2)C(F)(F)F)n(C)n1	InChI=1S/C16H15F3N4/c1-11-7-15(22(2)21-11)10-23-9-13(8-20-23)12-3-5-14(6-4-12)16(17,18)19/h3-9H,10H2,1-2H3	XYCBFPMJNPHKTB-UHFFFAOYSA-N	310997	US10155727, Example 51::USRE49517, Example 51	Potassium voltage-gated channel subfamily H member 2	Human		 9210							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310997&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796700	382366865							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597991	Cc1cc(Cn2cc(cn2)-c2ccc(C)c(F)c2)n(C)n1	InChI=1S/C16H17FN4/c1-11-4-5-13(7-16(11)17)14-8-18-21(9-14)10-15-6-12(2)19-20(15)3/h4-9H,10H2,1-3H3	FOMRZINSAAHONZ-UHFFFAOYSA-N	310998	US10155727, Example 52::USRE49517, Example 52	Potassium voltage-gated channel subfamily H member 2	Human		 522							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310998	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310998&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864389	382366866							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597992	Cc1ccc(cc1F)-c1cnn(Cc2ccn(C)n2)c1	InChI=1S/C15H15FN4/c1-11-3-4-12(7-15(11)16)13-8-17-20(9-13)10-14-5-6-19(2)18-14/h3-9H,10H2,1-2H3	UNVAEEDDPCWGMY-UHFFFAOYSA-N	310999	US10155727, Example 53	Potassium voltage-gated channel subfamily H member 2	Human		 3840							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=310999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=310999&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864259	382366867							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597993	Cc1cc(Cn2cc(cn2)-c2ccc(F)c(C)c2)n(C)n1	InChI=1S/C16H17FN4/c1-11-6-13(4-5-16(11)17)14-8-18-21(9-14)10-15-7-12(2)19-20(15)3/h4-9H,10H2,1-3H3	BWVRPGYKZYASIH-UHFFFAOYSA-N	311040	US10155727, Example 54::USRE49517, Example 54	Potassium voltage-gated channel subfamily H member 2	Human		 522							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311040	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311040&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864218	382366908							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597994	Cc1cc(ccc1F)-c1cnn(Cc2ccn(C)n2)c1	InChI=1S/C15H15FN4/c1-11-7-12(3-4-15(11)16)13-8-17-20(9-13)10-14-5-6-19(2)18-14/h3-9H,10H2,1-2H3	OPNJBKUMFOXMHL-UHFFFAOYSA-N	311000	US10155727, Example 55::USRE49517, Example 55	Potassium voltage-gated channel subfamily H member 2	Human		 871							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311000&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864216	382366868							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597995	Cc1cc(ccc1F)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H13FN4/c1-10-6-11(2-3-14(10)15)12-7-17-19(8-12)9-13-4-5-16-18-13/h2-8H,9H2,1H3,(H,16,18)	JUIQWZMUESSJRP-UHFFFAOYSA-N	311001	US10155727, Example 56::USRE49517, Example 56	Potassium voltage-gated channel subfamily H member 2	Human		 78.7							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864355	382366869							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597996	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(C)c2)n(C)n1	InChI=1S/C16H17ClN4/c1-11-6-13(4-5-16(11)17)14-8-18-21(9-14)10-15-7-12(2)19-20(15)3/h4-9H,10H2,1-3H3	NVPPRZHNQAGZNI-UHFFFAOYSA-N	311002	US10155727, Example 57::USRE49517, Example 57	Potassium voltage-gated channel subfamily H member 2	Human		 967							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311002&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864250	382366870							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597997	Cc1cc(ccc1Cl)-c1cnn(Cc2ccn(C)n2)c1	InChI=1S/C15H15ClN4/c1-11-7-12(3-4-15(11)16)13-8-17-20(9-13)10-14-5-6-19(2)18-14/h3-9H,10H2,1-2H3	AENUUQTUDHOBSJ-UHFFFAOYSA-N	311003	US10155727, Example 58::USRE49517, Example 58	Potassium voltage-gated channel subfamily H member 2	Human		 668							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864187	382366871							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597998	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)c(F)c2)n1	InChI=1S/C14H12ClFN4/c1-19-5-4-12(18-19)9-20-8-11(7-17-20)10-2-3-13(15)14(16)6-10/h2-8H,9H2,1H3	PXLCOAZGYOBHBQ-UHFFFAOYSA-N	311004	US10155727, Example 59::USRE49517, Example 59	Potassium voltage-gated channel subfamily H member 2	Human		 2190							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311004	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311004&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864331	382366872							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
597999	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(F)c2)n(C)n1	InChI=1S/C15H14ClFN4/c1-10-5-13(20(2)19-10)9-21-8-12(7-18-21)11-3-4-14(16)15(17)6-11/h3-8H,9H2,1-2H3	XYGIAPGACDFNDM-UHFFFAOYSA-N	311005	US10155727, Example 60::USRE49517, Example 60	Potassium voltage-gated channel subfamily H member 2	Human		 2170							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311005	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311005&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864478	382366873							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598000	Cn1ccc(Cn2cc(cn2)-c2ccc(F)c(Cl)c2)n1	InChI=1S/C14H12ClFN4/c1-19-5-4-12(18-19)9-20-8-11(7-17-20)10-2-3-14(16)13(15)6-10/h2-8H,9H2,1H3	PVABBWISXQDWEN-UHFFFAOYSA-N	311006	US10155727, Example 61::USRE49517, Example 61	Potassium voltage-gated channel subfamily H member 2	Human		 1380							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311006&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864265	382366874							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598001	Cc1cc(Cn2cc(cn2)-c2ccc(F)c(Cl)c2)n(C)n1	InChI=1S/C15H14ClFN4/c1-10-5-13(20(2)19-10)9-21-8-12(7-18-21)11-3-4-15(17)14(16)6-11/h3-8H,9H2,1-2H3	DDHFRTPLOOOEAP-UHFFFAOYSA-N	311007	US10155727, Example 62::USRE49517, Example 62	Potassium voltage-gated channel subfamily H member 2	Human		 857							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311007&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864420	382366875							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598002	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)c(Cl)c2)n1	InChI=1S/C14H12Cl2N4/c1-19-5-4-12(18-19)9-20-8-11(7-17-20)10-2-3-13(15)14(16)6-10/h2-8H,9H2,1H3	MWFSWLFIGXOGQC-UHFFFAOYSA-N	311008	US10155727, Example 63::USRE49517, Example 63	Potassium voltage-gated channel subfamily H member 2	Human		 612							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311008	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311008&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864324	382366876							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598003	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)c(Cl)c2)n(C)n1	InChI=1S/C15H14Cl2N4/c1-10-5-13(20(2)19-10)9-21-8-12(7-18-21)11-3-4-14(16)15(17)6-11/h3-8H,9H2,1-2H3	CYBVKIGZLGUYOT-UHFFFAOYSA-N	311009	US10155727, Example 64::USRE49517, Example 64	Potassium voltage-gated channel subfamily H member 2	Human		 1100							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311009	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311009&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864352	382366877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598004	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)cc2Cl)n(C)n1	InChI=1S/C15H14Cl2N4/c1-10-5-13(20(2)19-10)9-21-8-11(7-18-21)14-4-3-12(16)6-15(14)17/h3-8H,9H2,1-2H3	DOLSUXNRMMOQGK-UHFFFAOYSA-N	311010	US10155727, Example 65::USRE49517, Example 65	Potassium voltage-gated channel subfamily H member 2	Human		 3810							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311010&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864220	382366878							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598005	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)cc2Cl)n1	InChI=1S/C14H12Cl2N4/c1-19-5-4-12(18-19)9-20-8-10(7-17-20)13-3-2-11(15)6-14(13)16/h2-8H,9H2,1H3	WVXIDDGREBYPIF-UHFFFAOYSA-N	311011	US10155727, Example 66::USRE49517, Example 66	Potassium voltage-gated channel subfamily H member 2	Human		 5210							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311011&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864458	382366879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598006	COc1cc(F)ccc1-c1cnn(Cc2ccn(C)n2)c1	InChI=1S/C15H15FN4O/c1-19-6-5-13(18-19)10-20-9-11(8-17-20)14-4-3-12(16)7-15(14)21-2/h3-9H,10H2,1-2H3	MSGIBHWJHGBUEJ-UHFFFAOYSA-N	311041	US10155727, Example 67	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311041&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864327	382366909							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598007	COc1cc(F)ccc1-c1cnn(Cc2cc(C)nn2C)c1	InChI=1S/C16H17FN4O/c1-11-6-14(20(2)19-11)10-21-9-12(8-18-21)15-5-4-13(17)7-16(15)22-3/h4-9H,10H2,1-3H3	UYFOFEJPPDSOCE-UHFFFAOYSA-N	311042	US10155727, Example 68::USRE49517, Example 68	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311042&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864294	382366910							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598008	C(c1cc[nH]n1)n1cc(cn1)-c1cccc(c1)C1CC1	InChI=1S/C16H16N4/c1-2-13(12-4-5-12)8-14(3-1)15-9-18-20(10-15)11-16-6-7-17-19-16/h1-3,6-10,12H,4-5,11H2,(H,17,19)	WTIFREIJFMTPOT-UHFFFAOYSA-N	311012	US10155727, Example 69::USRE49517, Example 69	Potassium voltage-gated channel subfamily H member 2	Human		 831							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311012	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311012&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796701	382366880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598009	CS(=O)(=O)c1cccc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H14N4O2S/c1-21(19,20)14-4-2-3-11(7-14)12-8-16-18(9-12)10-13-5-6-15-17-13/h2-9H,10H2,1H3,(H,15,17)	RAFYHYBKKVGIIK-UHFFFAOYSA-N	311013	US10155727, Example 70::USRE49517, Example 70	Potassium voltage-gated channel subfamily H member 2	Human		 2690							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311013	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311013&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796702	382366881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598010	Cn1cc(Cn2cc(cn2)-c2cccc(c2)S(C)(=O)=O)cn1	InChI=1S/C15H16N4O2S/c1-18-9-12(7-16-18)10-19-11-14(8-17-19)13-4-3-5-15(6-13)22(2,20)21/h3-9,11H,10H2,1-2H3	WMUAUDVHENODTB-UHFFFAOYSA-N	311014	US10155727, Example 71::USRE49517, Example 71	Potassium voltage-gated channel subfamily H member 2	Human		 9330							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311014&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864180	382366882							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598011	FS(F)(F)(F)(F)c1cccc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C13H11F5N4S/c14-23(15,16,17,18)13-3-1-2-10(6-13)11-7-20-22(8-11)9-12-4-5-19-21-12/h1-8H,9H2,(H,19,21)	MGNZNJFHDRDPLZ-UHFFFAOYSA-N	311015	US10155727, Example 72::USRE49517, Example 72	Potassium voltage-gated channel subfamily H member 2	Human		 95.1							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311015&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864351	382366883							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598012	Cc1n[nH]c(C)c1CCn1cc(cn1)-c1ccc(Cl)cc1	InChI=1S/C16H17ClN4/c1-11-16(12(2)20-19-11)7-8-21-10-14(9-18-21)13-3-5-15(17)6-4-13/h3-6,9-10H,7-8H2,1-2H3,(H,19,20)	FKNGDDYLLFMSCD-UHFFFAOYSA-N	311016	US10155727, Example 73::USRE49517, Example 73	Potassium voltage-gated channel subfamily H member 2	Human		 1157							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311016&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864330	382366884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598013	Cc1cc(Cn2cc(cn2)-c2ccc(Cl)cc2)n(C)n1	InChI=1S/C15H15ClN4/c1-11-7-15(19(2)18-11)10-20-9-13(8-17-20)12-3-5-14(16)6-4-12/h3-9H,10H2,1-2H3	IBXQVTJYUTXWOZ-UHFFFAOYSA-N	311017	US10155727, Example 74::USRE49517, Example 74	Potassium voltage-gated channel subfamily H member 2	Human		 6060							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864390	382366885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598014	Cn1ccc(Cn2cc(cn2)-c2ccc(Cl)cc2)n1	InChI=1S/C14H13ClN4/c1-18-7-6-14(17-18)10-19-9-12(8-16-19)11-2-4-13(15)5-3-11/h2-9H,10H2,1H3	WBSISSQHVCKNDV-UHFFFAOYSA-N	311018	US10155727, Example 75::USRE49517, Example 75	Potassium voltage-gated channel subfamily H member 2	Human		 3040							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311018	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311018&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864262	382366886							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598015	Cn1nccc1Cn1cc(cn1)-c1ccc(Cl)cc1	InChI=1S/C14H13ClN4/c1-18-14(6-7-16-18)10-19-9-12(8-17-19)11-2-4-13(15)5-3-11/h2-9H,10H2,1H3	OZKOQOLBOJMIRC-UHFFFAOYSA-N	311019	US10155727, Example 76::USRE49517, Example 76	Potassium voltage-gated channel subfamily H member 2	Human		 7350							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864396	382366887							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598016	Clc1ccc(cc1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C13H11ClN4/c14-12-3-1-10(2-4-12)11-7-16-18(8-11)9-13-5-6-15-17-13/h1-8H,9H2,(H,15,17)	ONBFZEJYXQDCRE-UHFFFAOYSA-N	311020	US10155727, Example 77::USRE49517, Example 77	Potassium voltage-gated channel subfamily H member 2	Human		 1040							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311020	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311020&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864360	382366888							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598017	Cn1cc(Cn2cc(cn2)-c2ccc(Cl)cc2)cn1	InChI=1S/C14H13ClN4/c1-18-8-11(6-16-18)9-19-10-13(7-17-19)12-2-4-14(15)5-3-12/h2-8,10H,9H2,1H3	HXXKCCOYYFKOHT-UHFFFAOYSA-N	311021	US10155727, Example 78::USRE49517, Example 78	Potassium voltage-gated channel subfamily H member 2	Human		 8280							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864438	382366889							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598018	Cn1ccc(Cn2cc(cn2)-c2ccc(Br)cc2)n1	InChI=1S/C14H13BrN4/c1-18-7-6-14(17-18)10-19-9-12(8-16-19)11-2-4-13(15)5-3-11/h2-9H,10H2,1H3	YZCWRAFJWAFRHN-UHFFFAOYSA-N	311022	US10155727, Example 79	Potassium voltage-gated channel subfamily H member 2	Human		 4720							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311022	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311022&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864276	382366890							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598019	Cc1cc(Cn2cc(cn2)-c2cccc(Br)c2)n(C)n1	InChI=1S/C15H15BrN4/c1-11-6-15(19(2)18-11)10-20-9-13(8-17-20)12-4-3-5-14(16)7-12/h3-9H,10H2,1-2H3	ANQAUDCJANAJOF-UHFFFAOYSA-N	311024	US10155727, Example 81	Potassium voltage-gated channel subfamily H member 2	Human		 4630							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311024&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864387	382366892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598020	Cc1cc(Cn2cc(cn2)-c2cccc(Br)c2)n(C)n1	InChI=1S/C15H15BrN4/c1-11-6-15(19(2)18-11)10-20-9-13(8-17-20)12-4-3-5-14(16)7-12/h3-9H,10H2,1-2H3	ANQAUDCJANAJOF-UHFFFAOYSA-N	311024	US10155727, Example 81	Potassium voltage-gated channel subfamily H member 2	Human		 6210							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311024&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864387	382366892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598021	Cn1ccc(Cn2cc(cn2)-c2cccc(Br)c2)n1	InChI=1S/C14H13BrN4/c1-18-6-5-14(17-18)10-19-9-12(8-16-19)11-3-2-4-13(15)7-11/h2-9H,10H2,1H3	TWITWMGSBLVJJS-UHFFFAOYSA-N	311025	US10155727, Example 82	Potassium voltage-gated channel subfamily H member 2	Human		 2620							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311025&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864286	382366893							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598022	Cc1cc(Cn2cc(cn2)-c2cc(F)cc(F)c2)n(C)n1	InChI=1S/C15H14F2N4/c1-10-3-15(20(2)19-10)9-21-8-12(7-18-21)11-4-13(16)6-14(17)5-11/h3-8H,9H2,1-2H3	KYGBERMNMHOSMC-UHFFFAOYSA-N	311026	US10155727, Example 83	Potassium voltage-gated channel subfamily H member 2	Human		 6020							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311026	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311026&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864345	382366894							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598023	Cn1ccc(Cn2cc(cn2)-c2cc(F)cc(F)c2)n1	InChI=1S/C14H12F2N4/c1-19-3-2-14(18-19)9-20-8-11(7-17-20)10-4-12(15)6-13(16)5-10/h2-8H,9H2,1H3	FBYLDXMRENBYNM-UHFFFAOYSA-N	311043	US10155727, Example 84	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311043	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311043&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864166	382366911							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598024	Cn1ccc(Cn2cc(cn2)-c2ccccc2)n1	InChI=1S/C14H14N4/c1-17-8-7-14(16-17)11-18-10-13(9-15-18)12-5-3-2-4-6-12/h2-10H,11H2,1H3	ZPLZKFHQDARNJQ-UHFFFAOYSA-N	311044	US10155727, Example 85	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311044	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311044&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			97250760	382366912							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598025	Cc1cc(Cn2cc(cn2)-c2ccccc2)n(C)n1	InChI=1S/C15H16N4/c1-12-8-15(18(2)17-12)11-19-10-14(9-16-19)13-6-4-3-5-7-13/h3-10H,11H2,1-2H3	TXJIMPPHALVHGH-UHFFFAOYSA-N	311045	US10155727, Example 86	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311045	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311045&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864230	382366913							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598026	Cn1nccc1Cn1cc(cn1)-c1ccccc1	InChI=1S/C14H14N4/c1-17-14(7-8-15-17)11-18-10-13(9-16-18)12-5-3-2-4-6-12/h2-10H,11H2,1H3	IVQOSXHMIKOTIP-UHFFFAOYSA-N	311046	US10155727, Example 87::USRE49517, Example 87	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311046	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311046&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864228	382366914							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598027	Cc1n[nH]c(C)c1Cn1cc(cn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H15ClF2N4O/c1-9-13(10(2)22-21-9)8-23-7-12(6-20-23)11-3-4-14(17)15(5-11)24-16(18)19/h3-7,16H,8H2,1-2H3,(H,21,22)	MQKNJFNIYSGNHY-UHFFFAOYSA-N	311027	US10155727, Example 88::USRE49517, Example 88	Potassium voltage-gated channel subfamily H member 2	Human		 152							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864226	382366895							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598028	Cc1n[nH]c(C)c1Cn1cc(cn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H15F3N4/c1-9-14(10(2)22-21-9)8-23-7-12(6-20-23)11-3-4-15(17)13(5-11)16(18)19/h3-7,16H,8H2,1-2H3,(H,21,22)	PAPFAZHJWWEGNJ-UHFFFAOYSA-N	311028	US10155727, Example 89::USRE49517, Example 89	Potassium voltage-gated channel subfamily H member 2	Human		 736							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311028	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311028&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864471	382366896							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598029	Cc1n[nH]c(C)c1Cn1cc(cn1)-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C17H17F3N4/c1-10-14(11(2)23-22-10)9-24-8-13(7-21-24)12-4-5-16(18)15(6-12)17(3,19)20/h4-8H,9H2,1-3H3,(H,22,23)	BRIBVXPWUHZXBX-UHFFFAOYSA-N	311029	US10155727, Example 90::USRE49517, Example 90	Potassium voltage-gated channel subfamily H member 2	Human		 422							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311029	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311029&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			130466755	382366897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598030	CCc1c[nH]nc1Cn1cc(cn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C16H15F3N4O/c1-2-10-6-20-22-14(10)9-23-8-12(7-21-23)11-3-4-13(17)15(5-11)24-16(18)19/h3-8,16H,2,9H2,1H3,(H,20,22)	IOOCAJSDFZHJMM-UHFFFAOYSA-N	311030	US10155727, Example 91::USRE49517, Example 91	Potassium voltage-gated channel subfamily H member 2	Human		 43.8							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311030	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311030&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864315	382366898							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598031	CCc1c[nH]nc1Cn1cc(cn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H15F3N4/c1-2-10-6-20-22-15(10)9-23-8-12(7-21-23)11-3-4-14(17)13(5-11)16(18)19/h3-8,16H,2,9H2,1H3,(H,20,22)	TVHCUYDPYVKDHI-UHFFFAOYSA-N	311031	US10155727, Example 92::USRE49517, Example 92	Potassium voltage-gated channel subfamily H member 2	Human		 71.2							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864439	382366899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598032	CC(F)(F)c1cccc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C15H14F2N4/c1-15(16,17)13-4-2-3-11(7-13)12-8-19-21(9-12)10-14-5-6-18-20-14/h2-9H,10H2,1H3,(H,18,20)	YUBYOLBZTMVIAV-UHFFFAOYSA-N	311032	US10155727, Example 93::USRE49517, Example 93	Potassium voltage-gated channel subfamily H member 2	Human		 25.2							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311032	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311032&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864321	382366900							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598033	FC(F)Oc1cccc(c1)-c1cnn(Cc2cc[nH]n2)c1	InChI=1S/C14H12F2N4O/c15-14(16)21-13-3-1-2-10(6-13)11-7-18-20(8-11)9-12-4-5-17-19-12/h1-8,14H,9H2,(H,17,19)	CIMZHFATSQYFET-UHFFFAOYSA-N	311033	US10155727, Example 94::USRE49517, Example 94	Potassium voltage-gated channel subfamily H member 2	Human		 279							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311033&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864325	382366901							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598034	CCn1cncc1Cn1cc(cn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C16H15ClF2N4/c1-2-22-10-20-7-13(22)9-23-8-12(6-21-23)11-3-4-15(17)14(5-11)16(18)19/h3-8,10,16H,2,9H2,1H3	PWOOSCZWCWFZKZ-UHFFFAOYSA-N	311034	US10155727, Example 95::USRE49517, Example 95	Potassium voltage-gated channel subfamily H member 2	Human		 63.5							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311034&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864200	382366902							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598035	CCn1cncc1Cn1cc(cn1)-c1ccc(F)c(C)c1	InChI=1S/C16H17FN4/c1-3-20-11-18-8-15(20)10-21-9-14(7-19-21)13-4-5-16(17)12(2)6-13/h4-9,11H,3,10H2,1-2H3	NTXJOFGNCFFNLA-UHFFFAOYSA-N	311035	US10155727, Example 96::USRE49517, Example 96	Potassium voltage-gated channel subfamily H member 2	Human		 77.8							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311035&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864422	382366903							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598037	CCn1cncc1Cn1cc(cn1)-c1ccc(Cl)cc1	InChI=1S/C15H15ClN4/c1-2-19-11-17-8-15(19)10-20-9-13(7-18-20)12-3-5-14(16)6-4-12/h3-9,11H,2,10H2,1H3	LBYWWSCGWDYKNX-UHFFFAOYSA-N	311036	US10155727, Example 98::USRE49517, Example 98	Potassium voltage-gated channel subfamily H member 2	Human		 1060							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864348	382366904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598039	Cn1nccc1-n1cc(cn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C13H10Cl2N4/c1-18-13(4-5-16-18)19-8-10(7-17-19)9-2-3-11(14)12(15)6-9/h2-8H,1H3	GUJNOPVPJRXDCB-UHFFFAOYSA-N	311037	US10155727, Example 100::USRE49517, Example 100	Potassium voltage-gated channel subfamily H member 2	Human		 3170							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311037	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311037&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864472	382366905							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598040	Cn1nccc1-n1cc(cn1)-c1ccc(F)c(Cl)c1	InChI=1S/C13H10ClFN4/c1-18-13(4-5-16-18)19-8-10(7-17-19)9-2-3-12(15)11(14)6-9/h2-8H,1H3	HRKHYYJXFPDNFI-UHFFFAOYSA-N	311038	US10155727, Example 101::USRE49517, Example 101	Potassium voltage-gated channel subfamily H member 2	Human		 5600							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311038&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864421	382366906							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598041	Clc1ccc(cc1)-c1cnn(Cc2cn3ccccc3n2)c1	InChI=1S/C17H13ClN4/c18-15-6-4-13(5-7-15)14-9-19-22(10-14)12-16-11-21-8-2-1-3-17(21)20-16/h1-11H,12H2	WQTXJFYTZBONCP-UHFFFAOYSA-N	311047	US10155727, Example 102::USRE49517, Example 102	Potassium voltage-gated channel subfamily H member 2	Human		>1000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864413	382366915							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598042	FC(F)c1cc(ccc1F)-c1cnn(Cc2cc(Cn3ccc(n3)-c3ccc(F)c(c3)C(F)F)n[nH]2)c1	InChI=1S/C25H18F6N6/c26-21-3-1-14(7-19(21)24(28)29)16-10-32-37(11-16)13-18-9-17(33-34-18)12-36-6-5-23(35-36)15-2-4-22(27)20(8-15)25(30)31/h1-11,24-25H,12-13H2,(H,33,34)	BGEGEEMDZPHRBZ-UHFFFAOYSA-N	311048	US10155727, Example 103::USRE49517, Example 103	Potassium voltage-gated channel subfamily H member 2	Human		>1000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311048	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311048&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137796703	382366916							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598043	Cn1ccc(Cn2cc(cn2)-c2ccccn2)n1	InChI=1S/C13H13N5/c1-17-7-5-12(16-17)10-18-9-11(8-15-18)13-4-2-3-6-14-13/h2-9H,10H2,1H3	MYVGSZBCKCBYMQ-UHFFFAOYSA-N	311049	US10155727, Example 104::USRE49517, Example 104	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311049&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864175	382366917							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
598044	Cc1cc(Cn2cc(cn2)-c2ccccn2)n(C)n1	InChI=1S/C14H15N5/c1-11-7-13(18(2)17-11)10-19-9-12(8-16-19)14-5-3-4-6-15-14/h3-9H,10H2,1-2H3	NMVFTNHCPXMRAP-UHFFFAOYSA-N	311050	US10155727, Example 105	Potassium voltage-gated channel subfamily H member 2	Human		>10000							US Patent		10.7270/Q2B85B66		aid1796313	US10155727	Schindler, R; Lankau, H; Hofgen, N; Grunwald, C; Egerland, U; Langen, B; Dost, R; Hage, T; Ward, S	12/18/2018	4/9/2019	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=311050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=311050&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118864269	382366918							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603581	C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@]2(CO1)c1nc(NC(=O)c2ccc(OC(F)F)cn2)cs1 |r,c:16|	InChI=1S/C25H23F2N5O4S2/c1-14-9-16-11-38-24(31-20(33)15-5-3-2-4-6-15)32-25(16,13-35-14)22-30-19(12-37-22)29-21(34)18-8-7-17(10-28-18)36-23(26)27/h2-8,10,12,14,16,23H,9,11,13H2,1H3,(H,29,34)(H,31,32,33)	JQUCWIWWWKZNCS-UHFFFAOYSA-N	312928	US9605007, Example 1::N-{2-[(4aR,6S,8aR)-2-Amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-5-(difluoromethoxy)pyridine-2-carboxamide ::US9744173, Example 1	Potassium voltage-gated channel subfamily H member 2	Human		 9900							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=312928	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=312928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435422	383539877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603582	C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@]2(CO1)c1nc(NC(=O)c2cnc(OC(F)F)cn2)cs1 |r,c:16|	InChI=1S/C24H22F2N6O4S2/c1-13-7-15-10-38-23(31-19(33)14-5-3-2-4-6-14)32-24(15,12-35-13)21-30-17(11-37-21)29-20(34)16-8-28-18(9-27-16)36-22(25)26/h2-6,8-9,11,13,15,22H,7,10,12H2,1H3,(H,29,34)(H,31,32,33)	TUOZDQRAUJQYNQ-UHFFFAOYSA-N	312929	US9605007, Example 2::N-{2-[(4aR,6S,8aR)-2-Amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-5-(difluoromethoxy)pyrazine-2-carboxamide ::US9744173, Example 2	Potassium voltage-gated channel subfamily H member 2	Human		 23600							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=312929	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=312929&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435478	383539878							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603583	C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@]2(CO1)c1nc(NC(=O)c2ccc(Cl)cn2)cs1 |r,c:16|	InChI=1S/C24H22ClN5O3S2/c1-14-9-16-11-35-23(29-20(31)15-5-3-2-4-6-15)30-24(16,13-33-14)22-28-19(12-34-22)27-21(32)18-8-7-17(25)10-26-18/h2-8,10,12,14,16H,9,11,13H2,1H3,(H,27,32)(H,29,30,31)	KVJVCXGPNSNZGV-UHFFFAOYSA-N	312930	US9605007, Example 7::N-{2-[(4a R, 6S,8aR)-2-Amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-5-chloropyridine-2-carboxamide ::US9744173, Example 7	Potassium voltage-gated channel subfamily H member 2	Human		 9000							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=312930	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=312930&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435445	383539879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603584	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2ncc(OC(F)F)cc2C)cs1 |r,c:7|	InChI=1S/C19H21F2N5O3S2/c1-9-3-12(29-17(20)21)5-23-14(9)15(27)24-13-7-30-16(25-13)19-8-28-10(2)4-11(19)6-31-18(22)26-19/h3,5,7,10-11,17H,4,6,8H2,1-2H3,(H2,22,26)(H,24,27)	CHAGAOAUIITKPC-UHFFFAOYSA-N	223400	US9315520, Example 45::US9315520, 45::US9605007, Example 45::US9744173, Example 45	Potassium voltage-gated channel subfamily H member 2	Human		 9600							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223400	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223400&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118435524	336285273							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603585	C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1cc(NC(=O)c2ccc(OC(F)F)cn2)ccc1F |r,c:7|	InChI=1S/C21H21F3N4O3S/c1-11-6-12-9-32-20(25)28-21(12,10-30-11)15-7-13(2-4-16(15)22)27-18(29)17-5-3-14(8-26-17)31-19(23)24/h2-5,7-8,11-12,19H,6,9-10H2,1H3,(H2,25,28)(H,27,29)	ZRDISNFFMHLYBW-UHFFFAOYSA-N	312936	US9605007, Comparator 3::US9744173, Comparator 4	Potassium voltage-gated channel subfamily H member 2	Human		 400							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=312936	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=312936&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118441559	383539885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603586	[H][C@@]12CCOC[C@@]1(N=C(N)SC2)c1cc(NC(=O)c2ccc(OC(F)F)cn2)ccc1F |t:8|	InChI=1S/C20H19F3N4O3S/c21-15-3-1-12(26-17(28)16-4-2-13(8-25-16)30-18(22)23)7-14(15)20-10-29-6-5-11(20)9-31-19(24)27-20/h1-4,7-8,11,18H,5-6,9-10H2,(H2,24,27)(H,26,28)	QRAMMCLVMBTOID-UHFFFAOYSA-N	223406	US9315520, Comparator 4::US9605007, Comparator 4	Potassium voltage-gated channel subfamily H member 2	Human		 500							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223406	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223406&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			45279898	336285274							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603587	NC1=N[C@]2(COCC[C@H]2CS1)c1cc(NC(=O)c2ccc(cn2)C#N)cs1 |r,t:1|	InChI=1S/C18H17N5O2S2/c19-6-11-1-2-14(21-7-11)16(24)22-13-5-15(26-9-13)18-10-25-4-3-12(18)8-27-17(20)23-18/h1-2,5,7,9,12H,3-4,8,10H2,(H2,20,23)(H,22,24)	LAOKNTCIMWLGDD-UHFFFAOYSA-N	312939	US9605007, Comparator 5::Ex. 64 of US 8198269	Potassium voltage-gated channel subfamily H member 2	Human		 1800							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=312939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=312939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			45279956	383539888							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
603588	[H][C@]12CSC(N)=N[C@]1(CO[C@@H](C)C2)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F |c:5|	InChI=1S/C20H20ClFN4O2S/c1-11-6-12-9-29-19(23)26-20(12,10-28-11)15-7-14(3-4-16(15)22)25-18(27)17-5-2-13(21)8-24-17/h2-5,7-8,11-12H,6,9-10H2,1H3,(H2,23,26)(H,25,27)	UOHXUSCZQJMWQO-UHFFFAOYSA-N	223358	US9315520, Comparator 7::US9605007, Comparator 7::US9744173, Comparator 7	Potassium voltage-gated channel subfamily H member 2	Human		 200							US Patent		10.7270/Q2JQ133S		aid1796409	US9605007	Brodney, MA; Beck, EM; Butler, CR; Zhang, L; O Neill, BT; Barreiro, G; LaChapelle, EA; Rogers, BN	3/28/2017	4/24/2019	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=223358	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=223358&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			45279589	336285233							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606384	CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(n1)-c1cccc(F)c1	InChI=1S/C27H23F2N7O3/c1-27(2,3)21-13-22(36(35-21)16-6-4-5-15(28)11-16)33-26(38)32-19-8-7-17(12-18(19)29)39-20-9-10-30-25-24(20)31-14-23(37)34-25/h4-14H,1-3H3,(H,30,34,37)(H2,32,33,38)	AJFKKXIBHCRFJO-UHFFFAOYSA-N	313750	US10167282, Compound TBAP-01	Potassium voltage-gated channel subfamily H member 2	Human		>100000							US Patent		10.7270/Q2GQ70V2		aid1796444	US10167282	Springer, CJ; Marais, R; Girotti, R; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Zambon, A	1/1/2019	4/24/2019	Cancer Research Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106774	383540635							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606385	Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)cc1F)C(C)(C)C	InChI=1S/C28H26FN7O3/c1-16-6-5-7-17(12-16)36-23(14-22(35-36)28(2,3)4)33-27(38)32-20-9-8-18(13-19(20)29)39-21-10-11-30-26-25(21)31-15-24(37)34-26/h5-15H,1-4H3,(H,30,34,37)(H2,32,33,38)	BPLDYDVBIOFLJB-UHFFFAOYSA-N	313751	US10167282, Compound TBAP-02	Potassium voltage-gated channel subfamily H member 2	Human		 65000							US Patent		10.7270/Q2GQ70V2		aid1796444	US10167282	Springer, CJ; Marais, R; Girotti, R; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Zambon, A	1/1/2019	4/24/2019	Cancer Research Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313751	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313751&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106775	383540636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606386	CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(n1)-c1cccc(c1)C(F)(F)F	InChI=1S/C28H23F4N7O3/c1-27(2,3)21-13-22(39(38-21)16-6-4-5-15(11-16)28(30,31)32)36-26(41)35-19-8-7-17(12-18(19)29)42-20-9-10-33-25-24(20)34-14-23(40)37-25/h4-14H,1-3H3,(H,33,37,40)(H2,35,36,41)	NVVFIJVZWGYGQT-UHFFFAOYSA-N	313752	US10167282, Compound TBAP-03	Potassium voltage-gated channel subfamily H member 2	Human		>100000							US Patent		10.7270/Q2GQ70V2		aid1796444	US10167282	Springer, CJ; Marais, R; Girotti, R; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Zambon, A	1/1/2019	4/24/2019	Cancer Research Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313752	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106776	383540637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606387	COc1cccc(c1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)cc1F)C(C)(C)C	InChI=1S/C28H26FN7O4/c1-28(2,3)22-14-23(36(35-22)16-6-5-7-17(12-16)39-4)33-27(38)32-20-9-8-18(13-19(20)29)40-21-10-11-30-26-25(21)31-15-24(37)34-26/h5-15H,1-4H3,(H,30,34,37)(H2,32,33,38)	QRJRSZXKVANUTL-UHFFFAOYSA-N	313753	US10167282, Compound TBAP-04	Potassium voltage-gated channel subfamily H member 2	Human		>100000							US Patent		10.7270/Q2GQ70V2		aid1796444	US10167282	Springer, CJ; Marais, R; Girotti, R; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Zambon, A	1/1/2019	4/24/2019	Cancer Research Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313753	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313753&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106777	383540638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606891	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCCCC1)c1cccnc1 |r,THB:8:9:16:12.13|			313960	Compound 8::US10167299, Example 8	Potassium voltage-gated channel subfamily H member 2	Human		>40000							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313960	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313960&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668175	383540845							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606892	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(C)=O)c1cccs1 |r,THB:8:9:16:12.13|	InChI=1S/C22H33N5OS/c1-14(2)22-25-24-15(3)27(22)19-12-17-7-8-18(13-19)26(17)10-9-20(23-16(4)28)21-6-5-11-29-21/h5-6,11,14,17-20H,7-10,12-13H2,1-4H3,(H,23,28)	YNBGIJVWMDWTHC-UHFFFAOYSA-N	314061	US10167299, Example 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9450							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=314061	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=314061&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118219325	383540943							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606893	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1cccs1 |r,THB:8:9:16:12.13|			313964	US10167299, Example 14	Potassium voltage-gated channel subfamily H member 2	Human		 3100							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313964&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668147	383540849							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606894	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCCCC1)c1cccs1 |r,THB:8:9:16:12.13|			313966	US10167299, Example 16	Potassium voltage-gated channel subfamily H member 2	Human		 3020							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			126585471	383540851							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606895	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCCC1)c1cccs1 |r,THB:8:9:16:12.13|			313968	US10167299, Example 18	Potassium voltage-gated channel subfamily H member 2	Human		 1890							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668192	383540853							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606896	CCC1CCC(CC1)C(=O)N[C@@H](CCN1C2CCC1CC(C2)n1c(C)nnc1C(C)C)c1ccsc1 |r,wU:11.11,TLB:22:20:14:16.17,(-7.11,8.92,;-5.78,8.15,;-5.78,6.61,;-4.44,5.84,;-4.44,4.3,;-5.78,3.53,;-7.11,4.3,;-7.11,5.84,;-5.78,1.99,;-7.11,1.22,;-4.44,1.22,;-4.44,-.32,;-3.11,-1.09,;-1.77,-.32,;-.44,-1.09,;.65,-2.18,;.65,-3.72,;1.1,-2.63,;1.1,-1.09,;2.44,-.33,;3.53,-1.42,;1.99,-1.42,;4.3,-.08,;3.82,1.38,;2.49,2.15,;5.07,2.29,;6.31,1.38,;5.84,-.08,;6.61,-1.42,;5.84,-2.75,;8.15,-1.42,;-5.78,-1.09,;-7.24,-.61,;-8.15,-1.86,;-7.24,-3.11,;-5.78,-2.63,)|	InChI=1S/C29H45N5OS/c1-5-21-6-8-22(9-7-21)29(35)30-27(23-13-15-36-18-23)12-14-33-24-10-11-25(33)17-26(16-24)34-20(4)31-32-28(34)19(2)3/h13,15,18-19,21-22,24-27H,5-12,14,16-17H2,1-4H3,(H,30,35)	BWGKFIQYNOWCMY-UHFFFAOYSA-N	313970	US10167299, Example 20	Potassium voltage-gated channel subfamily H member 2	Human		 14420							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313970&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			126585472	383540855							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606897	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccsc1 |r,THB:8:9:16:12.13|			313972	US10167299, Example 22	Potassium voltage-gated channel subfamily H member 2	Human		 10580							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668204	383540857							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606898	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCCC1)c1ccsc1 |r,THB:8:9:16:12.13|			313976	US10167299, Example 26	Potassium voltage-gated channel subfamily H member 2	Human		 3510							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313976	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313976&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668268	383540860							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606899	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccc(C)s1 |r,THB:8:9:16:12.13|			313979	US10167299, Example 73::US10167299, Example 29	Potassium voltage-gated channel subfamily H member 2	Human		 8440							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313979&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668272	383540863							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606900	CC(C)C(=O)N1CCc2c(C1)nc(C)n2C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccsc1 |r,TLB:23:22:15.21.16:18.19,14:15:22:18.19|	InChI=1S/C32H45F2N5O2S/c1-20(2)31(41)37-13-9-29-28(18-37)35-21(3)39(29)26-16-24-4-5-25(17-26)38(24)14-8-27(23-10-15-42-19-23)36-30(40)22-6-11-32(33,34)12-7-22/h10,15,19-20,22,24-27H,4-9,11-14,16-18H2,1-3H3,(H,36,40)	XADGEXPZZCPUIH-UHFFFAOYSA-N	313991	US10167299, Example 43	Potassium voltage-gated channel subfamily H member 2	Human		 1360							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122668181	383540875							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606901	CCc1ccc(s1)[C@H](CCN1C2CCC1CC(C2)n1c(C)nnc1C(C)C)NC(=O)C1CCCCC1 |r,TLB:18:16:10:12.13|	InChI=1S/C29H45N5OS/c1-5-25-13-14-27(36-25)26(30-29(35)21-9-7-6-8-10-21)15-16-33-22-11-12-23(33)18-24(17-22)34-20(4)31-32-28(34)19(2)3/h13-14,19,21-24,26H,5-12,15-18H2,1-4H3,(H,30,35)	UDRZSXGBJMNBJU-UHFFFAOYSA-N	313993	US10167299, Example 65	Potassium voltage-gated channel subfamily H member 2	Human		 840							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=313993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=313993&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118219320	383540877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606902	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCCCC1)c1sc(C)cc1C |r,THB:8:9:16:12.13|	InChI=1S/C29H45N5OS/c1-18(2)28-32-31-21(5)34(28)25-16-23-11-12-24(17-25)33(23)14-13-26(27-19(3)15-20(4)36-27)30-29(35)22-9-7-6-8-10-22/h15,18,22-26H,6-14,16-17H2,1-5H3,(H,30,35)	AZRFVIWFIFLGRH-UHFFFAOYSA-N	314062	US10167299, Example 101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 810							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=314062	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=314062&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118219337	383540944							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606903	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1sc(C)c(C)c1C |r,THB:8:9:16:12.13|	InChI=1S/C30H45F2N5OS/c1-17(2)28-35-34-21(6)37(28)25-15-23-7-8-24(16-25)36(23)14-11-26(27-19(4)18(3)20(5)39-27)33-29(38)22-9-12-30(31,32)13-10-22/h17,22-26H,7-16H2,1-6H3,(H,33,38)	AMFXFRYUUCYQQD-UHFFFAOYSA-N	314063	US10167299, Example 103	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3470							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=314063	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=314063&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118219339	383540945							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606904	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCCCC1)c1cc2OCOc2s1 |r,THB:8:9:16:12.13|	InChI=1S/C28H41N5O3S/c1-17(2)26-31-30-18(3)33(26)22-13-20-9-10-21(14-22)32(20)12-11-23(25-15-24-28(37-25)36-16-35-24)29-27(34)19-7-5-4-6-8-19/h15,17,19-23H,4-14,16H2,1-3H3,(H,29,34)	UWGLWJUEXIKBEE-UHFFFAOYSA-N	314064	US10167299, Example 107	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=314064	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=314064&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118219281	383540946							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606905	CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1	InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3	IXTMWRCNAAVVAI-UHFFFAOYSA-N	50031720	(Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-phenyl)-ethyl]-methylamino}-ethoxy)-phenyl]-methanesulfonamide::DOFETILIDE::N-[4-(2-{[2-(4-Methanesulfonylamino-phenyl)-ethyl]-methyl-amino}-ethoxy)-phenyl]-methanesulfonamide (UK-68798)::N-[4-(2-{[2-(4-Methanesulfonylamino-phenyl)-ethyl]-methyl-amino}-ethoxy)-phenyl]-methanesulfonamide (dofetilide)::CHEMBL473::N-[4-(2-{[2-(4-methanesulfonylamino-phenoxy)-ethyl]-methyl-amino}-ethyl)-phenyl]-methanesulfonamide::TIKOSYN::UK-68,798::N-[4-(2-{[2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-METHYL-AMINO}-ETHOXY)-PHENYL]-METHANESULFONAMIDE DOFETILIDE::US10167299, Dofetilide	Potassium voltage-gated channel subfamily H member 2	Human		 90.0							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031720	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031720&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71329	103940282	4681	CHEMBL473	DB00204		C07751		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606906	COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC	InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)	DCSUBABJRXZOMT-UHFFFAOYSA-N	50005836	4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::PROPULSID::CHEMBL560739::cid_5311047::CISAPRIDE::4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::US9221790, Cisapride::US10167299, Cisapride::US10800776, Example Cisapride	Potassium voltage-gated channel subfamily H member 2	Human		 190							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			2769	103919261	95129	CHEMBL560739			C06910		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
606907	CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1 |r,TLB:17:16:12.13:15.10.9,THB:8:9:16:12.13|			160935	US9107954, maraviroc::US10167299, Maraviroc	Potassium voltage-gated channel subfamily H member 2	Human		 7750							US Patent		10.7270/Q2V126X2		aid1796457	US10167299	Liu, H; Wu, B; Zheng, Y; Xie, X; Jiang, H; Peng, P; Luo, R; Li, J; Li, J; Zhu, Y; Chen, Y; Zhang, H; Yang, L; Zhou, Y; Chen, K	1/1/2019	4/24/2019	Shanghai Institute of Material Medica, Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=160935	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=160935&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			483407	295369650	94963						1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616128	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(F)cncc1F	InChI=1S/C24H19F3N4O2/c25-18-4-1-14(24(32)22-19(26)11-28-12-20(22)27)9-17(18)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	UTPQVJZOHIQDGB-UHFFFAOYSA-N	315505	US10172859, Example 1::(3,5-Difluoro-pyridin-4- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.50 (s, 2H), 7.65-7.60 (m, 2H), 7.55-7.48 (m, 2H), 7.45-7.40 (m, 1H), 7.20 (d, J = 2.1, 1H), 6.62 (d, J = 4.6, 1H), 6.23 (d, J = 4.6, 1H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US9732094, Example 1::US11065253, Example 1	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315505&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696291	383542264							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616130	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(F)c1Cl	InChI=1S/C24H19ClF2N4O2/c25-22-18(11-28-12-20(22)27)24(32)14-1-4-19(26)17(9-14)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	KJBYMUZTLUOOTH-UHFFFAOYSA-N	315511	US10172859, Example 2::(4-Chloro-5-fluoro- pyridin-3-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.70 (s, 1H), 8.66 (s, 1H), 7.64-7.59 (m, 2H), 7.55- 7.48 (m, 2H), 7.44-7.39 (m, 1H), 7.20 (d, J = 2.2, 1H), 6.56 (d, J = 4.4, 1H), 6.12 (d, J = 4.5, 1H), 3.81- 3.74 (m, 4H), 3.47-3.40 (m, 4H)::US9732094, Example 2::US11065253, Example 2	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315511&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86294562	383542270							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616132	COc1ccnnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-21-4-5-29-30-23(21)24(32)16-11-17(19(26)12-18(16)25)22-15-3-2-14(10-20(15)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	LMRHWYRLOVDZKO-UHFFFAOYSA-N	315513	US10172859, Example 3::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (4-methoxy-pyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H), 8.96 (d, J = 6.0, 1H), 8.04-8.01 (m, 1H), 7.65- 7.60 (m, 2H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.32 (d, J = 6.0, 1H), 7.22 (d, J = 2.5, 1H), 6.46 (d, J = 6.2, 1H), 6.39 (d, J = 6.3, 1H), 3.96 (s, 3H), 3.81-3.75 (m, 4H), 3.50-3.43 (m, 4H)::US9732094, Example 3::US11065253, Example 3	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315513&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954887	383542272							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616134	COc1nnccc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-16(4-5-29-30-24)23(32)17-11-18(20(26)12-19(17)25)22-15-3-2-14(10-21(15)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	NYDMCEVKGDKDIY-UHFFFAOYSA-N	315576	US10172859, Example 4::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s, 1H), 8.88 (d, J = 4.7, 1H), 7.71 (d, J = 9.5, 1H), 7.59 (dd, J = 4.7, 0.9, 1H), 7.54 (d, J = 7.6, 1H), 7.52-7.50 (m, 2H), 7.21-7.17 (m, 1H), 6.46 (d, J = 5.1, 1H), 6.15 (d, J = 5.2, 1H), 4.01 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US9732094, Example 4::US11065253, Example 4	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315576&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966363	383542335							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616136	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncc[nH]c1=O	InChI=1S/C23H20FN5O3/c24-18-4-1-14(22(30)21-23(31)26-6-5-25-21)11-17(18)20-16-3-2-15(12-19(16)27-13-28-20)29-7-9-32-10-8-29/h1-6,11-13,22,30H,7-10H2,(H,26,31)	FMSCJXCEGBUMCL-UHFFFAOYSA-N	315577	US10172859, Example 5::3-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-1H- pyrazin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.69-7.59 (m, 2H), 7.56-7.50 (m, 2H), 7.39- 7.28 (m, 3H), 7.20 (d, J = 2.1, 1H), 6.00 (s, 1H), 5.87-5.75 (m, 1H), 3.81-3.74 (m, 4H), 3.44 (t, J = 5.0, 4H)::US9732094, Example 5::US11065253, Example 5	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315577	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315577&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106835	383542336							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616138	COc1nnc(Cl)cc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20Cl2FN5O3/c1-34-24-17(10-21(26)30-31-24)23(33)15-9-16(19(27)11-18(15)25)22-14-3-2-13(8-20(14)28-12-29-22)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	ZGAJFLBXEVLQHV-UHFFFAOYSA-N	315579	US10172859, Example 6::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-chloro-5-methoxy- pyridazin-3-yl) methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s, 1H), 7.75 (d, J = 1.0, 1H), 7.72 (d, J = 9.5, 1H), 7.56 (d, J = 7.6, 1H), 7.51 (dd, J = 9.5, 2.5, 1H), 7.47 (dd, J = 9.4, 2.9, 1H), 7.19 (d, J = 2.4, 1H), 6.59 (d, J = 5.0, 1H), 6.13-6.10 (m, 1H), 3.98 (s, 3H), 3.80-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US9732094, Example 6::US11065253, Example 6	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315579&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966366	383542338							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616140	COc1cc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Cl)nn1	InChI=1S/C24H21ClFN5O3/c1-33-21-12-18(24(25)30-29-21)23(32)14-2-5-19(26)17(10-14)22-16-4-3-15(11-20(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	KSMYOVIQSVHQKI-UHFFFAOYSA-N	315580	US10172859, Example 7::(3-Chloro-6-methoxy- pyridazin-4-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.62-7.57 (m, 2H), 7.55-7.47 (m, 3H), 7.43- 7.39 (m, 1H), 7.20 (d, J = 2.4, 1H), 6.58 (d, J = 4.5, 1H), 5.88 (d, J = 4.4, 1H), 4.04 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US9732094, Example 7::US11065253, Example 7	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315580	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315580&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86294560	383542339							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616142	COc1cc(Cl)nnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20Cl2FN5O3/c1-34-20-11-21(26)30-31-23(20)24(33)15-9-16(18(27)10-17(15)25)22-14-3-2-13(8-19(14)28-12-29-22)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	URDZKJLOZSFJOE-UHFFFAOYSA-N	315581	US10172859, Example 8::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-chloro-4-methoxy- pyridazin-3-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H), 8.01-7.99 (m, 1H), 7.65-7.59 (m, 3H), 7.56 (dd, J = 9.5, 2.5, 1H), 7.22 (d, J = 2.5, 1H), 6.52 (d, J = 6.2, 1H), 6.39 (d, J = 6.2, 1H), 4.02 (s, 3H), 3.80-3.76 (m, 4H), 3.48-3.44 (m, 4H)::US9732094, Example 8::US11065253, Example 8	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315581	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315581&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954988	383542340							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616144	COc1nnc(Cl)cc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-18(12-21(25)29-30-24)23(32)14-2-5-19(26)17(10-14)22-16-4-3-15(11-20(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	PBEWANFAIGVJRA-UHFFFAOYSA-N	315582	US10172859, Example 286::(6-Chloro-5-methoxy- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.88 (d, J = 1.0, 1H), 7.63-7.58 (m, 2H), 7.55- 7.47 (m, 2H), 7.42-7.35 (m, 1H), 7.20 (d, J = 2.3, 1H), 6.46 (d, J = 4.3, 1H), 5.85-5.82 (m, 1H), 4.00 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 9::US9732094, Example 286::US11065253, Example 286	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315582&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954747	383542341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616146	COc1cc(Cl)nnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-20-12-21(25)29-30-23(20)24(32)14-2-5-18(26)17(10-14)22-16-4-3-15(11-19(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	LAPIHKKQBZORLI-UHFFFAOYSA-N	315583	US10172859, Example 10::(6-Chloro-4-methoxy- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.64-7.60 (m, 2H), 7.53-7.51 (m, 3H), 7.40- 7.35 (m, 1H), 7.21-7.19 (m, 1H), 6.29 (d, J = 5.3, 1H), 6.18 (d, J = 4.3, 1H), 3.93 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US9732094, Example 10::US11065253, Example 10	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315583&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86294564	383542342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616148	COc1nnccc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-18(6-7-28-29-24)23(31)15-2-5-20(25)19(12-15)22-17-4-3-16(13-21(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	SLGPVTYHXWXXSC-UHFFFAOYSA-N	315584	US10172859, Example 12::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol (Ena 1)see racemate::US10172859, Example 19::US10172859, Example 11::US9732094, Example 19::US11065253, Example 19	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966365	383542343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616150	COc1nnccc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-18(6-7-28-29-24)23(31)15-2-5-20(25)19(12-15)22-17-4-3-16(13-21(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	SLGPVTYHXWXXSC-UHFFFAOYSA-N	315584	US10172859, Example 12::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol (Ena 1)see racemate::US10172859, Example 19::US10172859, Example 11::US9732094, Example 19::US11065253, Example 19	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966365	383542343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616152	CC(C)(C)Oc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H28FN5O3/c1-27(2,3)36-26-24(29-8-9-30-26)25(34)17-4-7-21(28)20(14-17)23-19-6-5-18(15-22(19)31-16-32-23)33-10-12-35-13-11-33/h4-9,14-16,25,34H,10-13H2,1-3H3	IHJXGTTTXOYFEL-UHFFFAOYSA-N	315586	US10172859, Example 13::(3-tert-Butoxy-pyrazin- 2-yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.14 (d, J = 2.7, 1H), 8.08 (d, J = 2.7, 1H), 7.63- 7.56 (m, 2H), 7.54-7.47 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 5.97 (d, J = 6.0, 1H), 5.91 (d, J = 6.1, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m, 4H), 1.47 (s, 9H)::US9732094, Example 13::US11065253, Example 13	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315586	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315586&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954800	383542344							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616154	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1N1CCCC1	InChI=1S/C27H27FN6O2/c28-22-6-3-18(26(35)25-27(30-8-7-29-25)34-9-1-2-10-34)15-21(22)24-20-5-4-19(16-23(20)31-17-32-24)33-11-13-36-14-12-33/h3-8,15-17,26,35H,1-2,9-14H2	GPLAQASQYVIJRV-UHFFFAOYSA-N	315587	US10172859, Example 14::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-pyrrolidin-1-yl- pyrazin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.99 (d, J = 2.4, 1H), 7.80 (d, J = 2.5, 1H), 7.58- 7.52 (m, 4H), 7.38-7.32 (m, 1H), 7.21-7.17 (m, 1H), 6.18-6.13 (m, 1H), 6.09-6.01 (m, 1H), 3.78 (t, J = 4.9, 4H), 3.68-3.56 (m, 4H), 3.44 (t, J = 4.9, 4H), 1.96-1.81 (m, 4H)::US9732094, Example 14::US11065253, Example 14	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315587&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954734	383542345							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616156	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)15-2-5-19(25)18(12-15)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QHNQVNYRYQEKGM-UHFFFAOYSA-N	315588	US10172859, Example 16::US10172859, Example 38::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methoxy-pyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 15::US9732094, Example 38::US11065253, Example 38	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292071	383542346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616158	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)15-2-5-19(25)18(12-15)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QHNQVNYRYQEKGM-UHFFFAOYSA-N	315588	US10172859, Example 16::US10172859, Example 38::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methoxy-pyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 15::US9732094, Example 38::US11065253, Example 38	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292071	383542346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616160	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(Cl)cncc1Cl	InChI=1S/C24H19Cl2FN4O2/c25-18-11-28-12-19(26)22(18)24(32)14-1-4-20(27)17(9-14)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	JUJIBZUQPZFDCW-UHFFFAOYSA-N	315591	US10172859, Example 17::(3,5-Dichloro-pyridin-4- yl)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.62 (s, 2H), 7.58-7.48 (m, 4H), 7.43-7.37 (m, 1H), 7.19 (d, J = 2.2, 1H), 6.70-6.65 (m, 1H), 6.52 (d, J = 4.7, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H)::US9732094, Example 17::US11065253, Example 17	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315591	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315591&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954735	383542348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616162	COc1ccnnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-21-6-7-28-29-23(21)24(31)15-2-5-19(25)18(12-15)22-17-4-3-16(13-20(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	CYGVNIZYJOHEKW-UHFFFAOYSA-N	315592	US10172859, Example 18::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (4-methoxy-pyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11-9.08 (m, 1H), 8.99-8.95 (m, 1H), 7.65-7.59 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.34 (m, 1H), 7.27 (d, J = 5.9, 1H), 7.22-7.18 (m, 1H), 6.24-6.18 (m, 2H), 3.88 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H)::US9732094, Example 18::US11065253, Example 18	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315592	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315592&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954974	383542349							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616164	COc1nnccc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-18(6-7-28-29-24)23(31)15-2-5-20(25)19(12-15)22-17-4-3-16(13-21(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	SLGPVTYHXWXXSC-UHFFFAOYSA-N	315584	US10172859, Example 12::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol (Ena 1)see racemate::US10172859, Example 19::US10172859, Example 11::US9732094, Example 19::US11065253, Example 19	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315584	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966365	383542343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616166	OC(c1ccc2nccn2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(25(34)21-3-4-23-28-5-6-33(23)31-21)12-17(19)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SBDSJWIXIDMXMK-UHFFFAOYSA-N	315594	US10172859, Example 51::US10172859, Example 21::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- itnidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate::US10172859, Example 20::US9732094, Example 51::US11065253, Example 51	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696725	383542350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616168	OC(c1ccc2nccn2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(25(34)21-3-4-23-28-5-6-33(23)31-21)12-17(19)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SBDSJWIXIDMXMK-UHFFFAOYSA-N	315594	US10172859, Example 51::US10172859, Example 21::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- itnidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate::US10172859, Example 20::US9732094, Example 51::US11065253, Example 51	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696725	383542350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616170	COc1cnc(Cl)c(c1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-33-17-12-20(25(26)28-13-17)24(32)15-2-5-21(27)19(10-15)23-18-4-3-16(11-22(18)29-14-30-23)31-6-8-34-9-7-31/h2-5,10-14,24,32H,6-9H2,1H3	WXRISZAPVAJOEF-UHFFFAOYSA-N	315596	US10172859, Example 22::(2-Chloro-5-methoxy- pyridin-3-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.28 (d, J = 2.6, 1H), 7.62-7.55 (m, 3H), 7.55- 7.49 (m, 2H), 7.41-7.32 (m, 1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.03 (d, J = 6.1, 1H), 3.85 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US9732094, Example 22::US11065253, Example 22	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315596&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291666	383542351							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616172	OC(c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C21H17ClFN5O2S/c22-21-18(24-3-4-25-21)19(29)12-1-2-14(23)13(9-12)17-20-15(26-11-27-17)10-16(31-20)28-5-7-30-8-6-28/h1-4,9-11,19,29H,5-8H2	SDVPZFAXJNURBD-UHFFFAOYSA-N	315597	US10172859, Example 24::(3-Chloro-pyrazin-2-yl)- [4-fluoro-3-(6- morpholin-4-yl-thieno- [3,2-d}pyrimidin-4-yl)- phenyl]methanol (Ena 1)identical to enantiomer (24)::US10172859, Example 37::US10172859, Example 23::US9732094, Example 37::US11065253, Example 37	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292070	383542352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616174	OC(c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C21H17ClFN5O2S/c22-21-18(24-3-4-25-21)19(29)12-1-2-14(23)13(9-12)17-20-15(26-11-27-17)10-16(31-20)28-5-7-30-8-6-28/h1-4,9-11,19,29H,5-8H2	SDVPZFAXJNURBD-UHFFFAOYSA-N	315597	US10172859, Example 24::(3-Chloro-pyrazin-2-yl)- [4-fluoro-3-(6- morpholin-4-yl-thieno- [3,2-d}pyrimidin-4-yl)- phenyl]methanol (Ena 1)identical to enantiomer (24)::US10172859, Example 37::US10172859, Example 23::US9732094, Example 37::US11065253, Example 37	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292070	383542352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616176	COc1ncc(Cl)nc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(30-20(25)12-27-24)23(32)14-2-5-18(26)17(10-14)21-16-4-3-15(11-19(16)28-13-29-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YRICZHMWIWNYIX-UHFFFAOYSA-N	315599	US10172859, Example 25::(6-Chloro-3-methoxy- pyrazin-2-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.30 (s, 1H), 7.65-7.60 (m, 2H), 7.57-7.51 (m, 2H), 7.43-7.36 (m, 1H), 7.22-7.19 (m, 1H), 6.18 (s, 1H), 6.06-6.02 (m, 1H), 3.94 (s, 3H), 3.81- 3.75 (m, 4H), 3.47-3.43 (m, 4H)::US9732094, Example 25::US11065253, Example 25	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315599&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291869	383542353							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616178	COc1cnc(Cl)c(n1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-20-12-27-24(25)22(30-20)23(32)14-2-5-18(26)17(10-14)21-16-4-3-15(11-19(16)28-13-29-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MFNKUHDJBOVSQS-UHFFFAOYSA-N	315600	US10172859, Example 26::(3-Chloro-6-methoxy- pyrazin-2-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.11 (s, 1H), 7.73-7.68 (m, 2H), 7.54-7.50 (m, 2H), 7.44-7.38 (m, 1H), 7.21-7.19 (m, 1H), 6.31 (d, J = 5.7, 1H), 6.11 (d, J = 5.8, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H)::US9732094, Example 26::US11065253, Example 26	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315600&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291868	383542354							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616180	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H19ClFN5O2/c24-23-21(26-5-6-27-23)22(31)14-1-4-18(25)17(11-14)20-16-3-2-15(12-19(16)28-13-29-20)30-7-9-32-10-8-30/h1-6,11-13,22,31H,7-10H2	SOXWGEFOMMQSBW-UHFFFAOYSA-N	315601	(R)-(3-Chloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanolsee racemate::US10172859, Example 54::US10172859, Example 28::US10172859, Example 27::US9732094, Example 54::US11065253, Example 54	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315601&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292264	383542355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616182	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H19ClFN5O2/c24-23-21(26-5-6-27-23)22(31)14-1-4-18(25)17(11-14)20-16-3-2-15(12-19(16)28-13-29-20)30-7-9-32-10-8-30/h1-6,11-13,22,31H,7-10H2	SOXWGEFOMMQSBW-UHFFFAOYSA-N	315601	(R)-(3-Chloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanolsee racemate::US10172859, Example 54::US10172859, Example 28::US10172859, Example 27::US9732094, Example 54::US11065253, Example 54	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315601&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292264	383542355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616184	OC(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-12-19(25)17(11-16(18)23(31)20-2-1-5-28-29-20)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	ZYGYHTYPQAHIIL-UHFFFAOYSA-N	315603	[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.7, 1H), 9.11 (s, 1H), 7.88 (d, J = 7.7, 1H), 7.80 (dd, J = 8.6, 1.7, 1H), 7.72-7.66 (m, 2H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (d, J = 5.0, 1H), 6.32 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 30::US10172859, Example 47::US10172859, Example 29::US9732094, Example 47::US11065253, Example 47	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292263	383542356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616186	OC(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-12-19(25)17(11-16(18)23(31)20-2-1-5-28-29-20)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	ZYGYHTYPQAHIIL-UHFFFAOYSA-N	315603	[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.7, 1H), 9.11 (s, 1H), 7.88 (d, J = 7.7, 1H), 7.80 (dd, J = 8.6, 1.7, 1H), 7.72-7.66 (m, 2H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (d, J = 5.0, 1H), 6.32 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 30::US10172859, Example 47::US10172859, Example 29::US9732094, Example 47::US11065253, Example 47	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292263	383542356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616188	COc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Cl)c1	InChI=1S/C25H22ClFN4O3/c1-33-17-12-20(26)24(28-13-17)25(32)15-2-5-21(27)19(10-15)23-18-4-3-16(11-22(18)29-14-30-23)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	WUHDWUZGBYYHTQ-UHFFFAOYSA-N	315605	US10172859, Example 31::(3-Chloro-5-methoxy- pyridin-2-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.28 (d, J = 2.6, 1H), 7.62-7.55 (m, 3H), 7 55- 7.49 (m, 2H), 7.41-7.32 (m, 1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.03 (d, J = 6.1, 1H), 3.85 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US9732094, Example 31::US11065253, Example 31	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315605	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315605&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291873	383542357							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616190	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC1COC1	InChI=1S/C26H24FN5O4/c27-21-4-1-16(25(33)24-26(29-6-5-28-24)36-18-13-35-14-18)11-20(21)23-19-3-2-17(12-22(19)30-15-31-23)32-7-9-34-10-8-32/h1-6,11-12,15,18,25,33H,7-10,13-14H2	GEZJANXQGHIRIL-UHFFFAOYSA-N	315606	US10172859, Example 32::[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- [3-(oxetan-3-yloxy)- pyrazin-2-yl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.24 (d, J = 2.7, 1H), 8.09 (d, J = 2.8, 1H), 7.71- 7.64 (m, 2H), 7.54-7.51 (m, 2H), 7.42-7.36 (m, 1H), 7.22-7.19 (m, 1H), 6.15-6.11 (m, 2H), 5.63- 5.58 (m, 1H), 4.88-4.83 (m, 2H), 4.58-4.52 (m, 2H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H)::US9732094, Example 32::US11065253, Example 32	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315606	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315606&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954854	383542358							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616192	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cnccn1	InChI=1S/C23H20FN5O2/c24-19-4-1-15(23(30)21-13-25-5-6-26-21)11-18(19)22-17-3-2-16(12-20(17)27-14-28-22)29-7-9-31-10-8-29/h1-6,11-14,23,30H,7-10H2	ASBXJSXOJUIGQQ-UHFFFAOYSA-N	315607	US10172859, Example 33::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyrazin-2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.89 (d, J = 1.5, 1H), 8.59-8.53 (m, 2H), 7.71- 7.65 (m, 2H), 7.57-7.50 (m, 2H), 7.44-7.37 (m, 1H), 7.21-7.19 (m, 1H), 5.94 (s, 1H), 3.81-3.75 (m, 4H), 3.49-3.44 (m, 4H)::US9732094, Example 33::US11065253, Example 33	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315607&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954758	383542359							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616194	OC(c1cnccn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-11-19(25)17(10-16(18)23(31)21-12-26-3-4-27-21)22-15-2-1-14(9-20(15)28-13-29-22)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	VXJBPIDEFGKNNZ-UHFFFAOYSA-N	315608	US10172859, Example 34::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyrazin-2-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.86 (d, J = 1.3, 1H), 8.58-8.55 (m, 2H), 7.88 (d, J = 7.7, 1H), 7.66 (d, J = 9.5, 1H), 7.60-7.52 (m, 2H), 7.21 (d, J = 2.3, 1H), 6.62 (d, J = 4.9, 1H), 6.19 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.49-3.42 (m, 4H)::US9732094, Example 34::US11065253, Example 34	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315608&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954905	383542360							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616196	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nc(Cl)cnc1Cl	InChI=1S/C23H18Cl2FN5O2/c24-19-11-27-23(25)21(30-19)22(32)13-1-4-17(26)16(9-13)20-15-3-2-14(10-18(15)28-12-29-20)31-5-7-33-8-6-31/h1-4,9-12,22,32H,5-8H2	XHOQZGNYQBPNLL-UHFFFAOYSA-N	315609	US10172859, Example 35::(3,6-Dichloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.63 (s, 1H), 7.68-7.64 (m, 2H), 7.55-7.51 (m, 2H), 7.45-7.40 (m, 1H), 7.20 (d, J = 2.1, 1H), 6.51 (d, J = 5.5, 1H), 6.18 (d, J = 5.5, 1H), 3.81-3.75 (m, 4H), 3.48-3.41 (m, 4H)::US9732094, Example 35::US11065253, Example 35	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315609&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291872	383542361							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616198	OC(c1ccnnc1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-19-11-20(25)18(10-17(19)23(31)14-3-4-28-29-12-14)22-16-2-1-15(9-21(16)26-13-27-22)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	USXKUTZDUWEZBD-UHFFFAOYSA-N	315610	US10172859, Example 36::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-4-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.27-9.25 (m, 1H), 9.19 (dd, J = 5.3, 1.2, 1H), 9.11 (s, 1H), 7.89 (d, J = 7.6, 1H), 7.72 (d, J = 9.5, 1H), 7.62- 7.56 (m, 2H), 7.53 (dd, J = 9.4, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.72 (s, 1H), 6.13 (s, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m, 4H)::US9732094, Example 36::US11065253, Example 36	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315610&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291871	383542362							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616200	OC(c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C21H17ClFN5O2S/c22-21-18(24-3-4-25-21)19(29)12-1-2-14(23)13(9-12)17-20-15(26-11-27-17)10-16(31-20)28-5-7-30-8-6-28/h1-4,9-11,19,29H,5-8H2	SDVPZFAXJNURBD-UHFFFAOYSA-N	315597	US10172859, Example 24::(3-Chloro-pyrazin-2-yl)- [4-fluoro-3-(6- morpholin-4-yl-thieno- [3,2-d}pyrimidin-4-yl)- phenyl]methanol (Ena 1)identical to enantiomer (24)::US10172859, Example 37::US10172859, Example 23::US9732094, Example 37::US11065253, Example 37	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292070	383542352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616202	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)15-2-5-19(25)18(12-15)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QHNQVNYRYQEKGM-UHFFFAOYSA-N	315588	US10172859, Example 16::US10172859, Example 38::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methoxy-pyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 15::US9732094, Example 38::US11065253, Example 38	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292071	383542346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616204	OC(c1ccn2nccc2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-4-6-33-23(31-21)3-5-30-33)24-16-2-1-15(11-22(16)28-14-29-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	DRBCELNQNRVAMX-UHFFFAOYSA-N	315613	US10172859, Example 39::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyrazolo[1,5-a]- pyrimidin-5-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 9.08 (dd, J = 7.2, 0.9, 1H), 8.19 (d, J = 2.4, 1H), 7.87 (d, J = 7.7, 1H), 7.69 (d, J = 9.5, 1H), 7.58 (dd, J = 9.4, 3.2, 1H), 7.52 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.5, 1H), 7.17 (d, J = 7.3, 1H), 6.71 (d, J = 5.0, 1H), 6.67 (dd, J = 2.3, 0.9, 1H), 6.11 (d, J = 4.8, 1H), 3.82- 3.74 (m, 4H), 3.49-3.41 (m, 4H)::US9732094, Example 39::US11065253, Example 39	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315613	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315613&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292072	383542363							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616206	COc1nnc(C(O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)c2ccncc12	InChI=1S/C27H22ClFN6O3/c1-37-27-20-13-30-5-4-16(20)25(33-34-27)26(36)18-11-19(22(29)12-21(18)28)24-17-3-2-15(10-23(17)31-14-32-24)35-6-8-38-9-7-35/h2-5,10-14,26,36H,6-9H2,1H3	OYABTHYQTFVSLR-UHFFFAOYSA-N	315614	US10172859, Example 40::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (4-methoxypyrido- [3,4-d}pyridazin-1-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.97 (s, 1H), 9.15 (s, 1H), 9.11 (d, J = 5.5, 1H), 8.10-8.02 (m, 2H), 7.73-7.62 (m, 2H), 7.57 (dd, J = 9.5, 2.5, 1H), 7.23 (d, J = 2.4, 1H), 6.95-6.87 (m, 2H), 4.18 (s, 3H), 3.84-3.74 (m, 4H), 3.52-3.41 (m, 4H)::US9732094, Example 40::US11065253, Example 40	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315614	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315614&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954879	383542364							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616208	OC(c1ccc(Cl)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H18Cl2FN5O2/c24-17-11-18(26)16(10-15(17)23(32)19-3-4-21(25)30-29-19)22-14-2-1-13(9-20(14)27-12-28-22)31-5-7-33-8-6-31/h1-4,9-12,23,32H,5-8H2	SXLLMNZBCYWXBH-UHFFFAOYSA-N	315615	US10172859, Example 41::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-chloro-pyridazin-3- yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 7.92-7.90 (m, 2H), 7.90-7.87 (m, 1H), 7.69 (d, J = 9.5, 1H), 7.58 (dd, J = 9.4, 3.2, 1H), 7.53 (dd, J = 9.5, 2.4, 1H), 7.20 (d, J = 2.3, 1H), 6.86 (d, J = 5.0, 1H), 6.32 (d, J = 4.5, 1H), 3.81-3.74 (m, 4H), 3.48- 3.43 (m, 4H)::US9732094, Example 41::US11065253, Example 41	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315615&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292073	383542365							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616210	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C24H20ClFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	IKPAUHLVUSUQBQ-UHFFFAOYSA-N	315616	US10172859, Example 465::US10172859, Example 466::(3-Chloro-pyridin-2-yl)- [4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.56 (dd, J = 4.6, 1.4, 1H), 7.92 (dd, J = 8.1, 1.4, 1H), 7.64-7.59 (m, 2H), 7.54-7.49 (m, 2H), 7.40- 7.34 (m, 2H), 7.22-7.17 (m, 1H), 6.21 (s, 1H), 6.18-6.09 (m, 1H), 3.81-3.73 (m, 4H), 3.48- 3.40 (m, 4H)::US10172859, Example 42::US9732094, Example 466::US11065253, Example 42	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292074	383542366							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616212	CNC(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-28-25(35)21-5-4-20(31-32-21)24(34)16-11-17(19(27)12-18(16)26)23-15-3-2-14(10-22(15)29-13-30-23)33-6-8-36-9-7-33/h2-5,10-13,24,34H,6-9H2,1H3,(H,28,35)	GHVIVLAZMTUKIH-UHFFFAOYSA-N	315617	US10172859, Example 43::6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid methylamide1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (q, J = 4.7, 1H), 9.11 (s, 1H), 8.19 (d, J = 8.7, 1H), 7.99 (d, J = 8.7, 1H), 7.87 (d, J = 7.7, 1H), 7.69 (d, J = 9.5, 1H), 7.58-7.51 (m, 2H), 7.22-7.19 (m, 1H), 6.84 (s, 1H), 6.42 (s, 1H), 3.80-3.76 (m, 4H), 3.47- 3.42 (m, 4H), 2.85 (d, J = 4.7, 3H)::US9732094, Example 43::US11065253, Example 43	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315617	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315617&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954990	383542367							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616214	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	TYZMCDRHMQABIJ-UHFFFAOYSA-N	315618	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- methyl-2H-pyridazin-3- one (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 7.93 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.61- 7.52 (m, 2H), 7.48 (d, J = 9.6, 1H), 7.21 (d, J = 2.4, 1H), 6.93 (d, J = 9.6, 1H), 6.60 (d, J = 4.8, 1H), 5.89 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.59 (s, 3H), 3.48-3.43 (m, 4H)::US10172859, Example 45::US10172859, Example 59::US10172859, Example 44::US9732094, Example 59::US11065253, Example 59	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954795	383542368							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616216	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	TYZMCDRHMQABIJ-UHFFFAOYSA-N	315618	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- methyl-2H-pyridazin-3- one (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 7.93 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.61- 7.52 (m, 2H), 7.48 (d, J = 9.6, 1H), 7.21 (d, J = 2.4, 1H), 6.93 (d, J = 9.6, 1H), 6.60 (d, J = 4.8, 1H), 5.89 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.59 (s, 3H), 3.48-3.43 (m, 4H)::US10172859, Example 45::US10172859, Example 59::US10172859, Example 44::US9732094, Example 59::US11065253, Example 59	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954795	383542368							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616218	Cc1cnnc(c1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O2/c1-14-8-22(30-29-12-14)24(32)17-10-18(20(26)11-19(17)25)23-16-3-2-15(9-21(16)27-13-28-23)31-4-6-33-7-5-31/h2-3,8-13,24,32H,4-7H2,1H3	IWIZEUGGMFCIBN-UHFFFAOYSA-N	315620	US10172859, Example 46::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 9.00 (d, J = 2.0, 1H), 7.87 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H), 7.63-7.61 (m, 1H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.65 (d, J = 4.9, 1H), 6.28 (d, J = 4.9, 1H), 3.80- 3.75 (m, 4H), 3.48-3.42 (m, 4H), 2.32 (s, 3H)::US9732094, Example 46::US11065253, Example 46	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315620&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954944	383542369							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616220	OC(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-12-19(25)17(11-16(18)23(31)20-2-1-5-28-29-20)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	ZYGYHTYPQAHIIL-UHFFFAOYSA-N	315603	[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.7, 1H), 9.11 (s, 1H), 7.88 (d, J = 7.7, 1H), 7.80 (dd, J = 8.6, 1.7, 1H), 7.72-7.66 (m, 2H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (d, J = 5.0, 1H), 6.32 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 30::US10172859, Example 47::US10172859, Example 29::US9732094, Example 47::US11065253, Example 47	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292263	383542356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616222	OC(c1cccnn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19F2N5O2/c24-18-12-19(25)17(23(31)20-2-1-5-28-29-20)11-16(18)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	DMVVLKYGVRDAES-UHFFFAOYSA-N	315622	US10172859, Example 48::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.6, 1H), 9.10 (s, 1H), 7.86 (dd, J = 8.5, 1.6, 1H), 7.81 (t, J = 8.1, 1H), 7.72 (dd, J = 8.5, 4.9, 1H), 7.58-7.51 (m, 2H), 7.46 (t, J = 10.1, 1H), 7.20 (d, J = 2.3, 1H), 6.66 (d, J = 4.9, 1H), 6.26 (d, J = 4.9, 1H), 3.81-3.75 (m, 4H), 3.45 (t, J = 4.9, 4H)::US9732094, Example 48::US11065253, Example 48	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315622&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954875	383542370							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616224	OC(c1ccc(Cl)nn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H18ClF2N5O2/c24-21-4-3-19(29-30-21)23(32)16-10-15(17(25)11-18(16)26)22-14-2-1-13(9-20(14)27-12-28-22)31-5-7-33-8-6-31/h1-4,9-12,23,32H,5-8H2	RYTVQFQGZIKYTM-UHFFFAOYSA-N	315623	US10172859, Example 49::(6-Chloro-pyridazin-3- yl)-[2,4-difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.98-7.91 (m, 2H), 7.82 (t, J = 8.1, 1H), 7.58-7.51 (m, 2H), 7.47 (t, J = 10.1, 1H), 7.20 (d, J = 2.3, 1H), 6.78 (d, J = 4.9, 1H) 6.26 (d, J = 4.6, 1H), 3.82- 3.74 (m, 4H), 3.48-3.41 (m, 4H).::US9732094, Example 49::US11065253, Example 49	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315623	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315623&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954910	383542371							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616226	CN(C)C(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H24ClFN6O3/c1-33(2)26(36)22-6-5-21(31-32-22)25(35)17-12-18(20(28)13-19(17)27)24-16-4-3-15(11-23(16)29-14-30-24)34-7-9-37-10-8-34/h3-6,11-14,25,35H,7-10H2,1-2H3	YUXWTDZVOLHXGC-UHFFFAOYSA-N	315624	US10172859, Example 50::6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid dimethylamide1H NMR (500 MHz, chloroform-d) ppm = 9.15 (s, 1H), 7.85 (d, J = 8.7, 1H), 7.79 (d, J = 7.4, 1H), 7.65 (d, J = 8.7, 1H), 7.56 (dd, J = 9.3, 3.3, 1H), 7.36 (d, J = 9.0, 1H), 7.27 (d, J = 2.5, 1H), 7.22 (d, J = 2.5, 1H), 6.54 (s, 1H), 4.99 (s, 1H), 3.92-3.87 (m, 4H), 3.46-3.42 (m, 4H), 3.22 (s, 3H), 3.19 (s, 3H)::US9732094, Example 50::US11065253, Example 50	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315624&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954844	383542372							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616228	OC(c1ccc2nccn2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(25(34)21-3-4-23-28-5-6-33(23)31-21)12-17(19)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SBDSJWIXIDMXMK-UHFFFAOYSA-N	315594	US10172859, Example 51::US10172859, Example 21::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- itnidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate::US10172859, Example 20::US9732094, Example 51::US11065253, Example 51	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696725	383542350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616230	COc1cnc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-13-26-21(12-27-22)24(31)15-2-5-19(25)18(10-15)23-17-4-3-16(11-20(17)28-14-29-23)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WYEVURVICOACEU-UHFFFAOYSA-N	315626	US10172859, Example 60::US10172859, Example 53::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyrazin-2- yl)methanol (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.39-8.38 (m, 1H), 8.23 (d, J = 1.3, 1H), 7.66- 7.61 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 6.30 (d, J = 4.4, 1H), 5.88 (d, J = 4.4, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US10172859, Example 52::US9732094, Example 60::US11065253, Example 60	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954847	383542373							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616232	COc1cnc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-13-26-21(12-27-22)24(31)15-2-5-19(25)18(10-15)23-17-4-3-16(11-20(17)28-14-29-23)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WYEVURVICOACEU-UHFFFAOYSA-N	315626	US10172859, Example 60::US10172859, Example 53::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyrazin-2- yl)methanol (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.39-8.38 (m, 1H), 8.23 (d, J = 1.3, 1H), 7.66- 7.61 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 6.30 (d, J = 4.4, 1H), 5.88 (d, J = 4.4, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US10172859, Example 52::US9732094, Example 60::US11065253, Example 60	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954847	383542373							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616234	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H19ClFN5O2/c24-23-21(26-5-6-27-23)22(31)14-1-4-18(25)17(11-14)20-16-3-2-15(12-19(16)28-13-29-20)30-7-9-32-10-8-30/h1-6,11-13,22,31H,7-10H2	SOXWGEFOMMQSBW-UHFFFAOYSA-N	315601	(R)-(3-Chloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanolsee racemate::US10172859, Example 54::US10172859, Example 28::US10172859, Example 27::US9732094, Example 54::US11065253, Example 54	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315601&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292264	383542355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616236	OC(c1ccc(nn1)C(O)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H19ClFN5O4/c25-17-11-18(26)16(10-15(17)23(32)19-3-4-20(24(33)34)30-29-19)22-14-2-1-13(9-21(14)27-12-28-22)31-5-7-35-8-6-31/h1-4,9-12,23,32H,5-8H2,(H,33,34)	FJAFQWYEJWQJQW-UHFFFAOYSA-N	315630	US10172859, Example 55::6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid1H NMR (500 MHz, DMSO-d6) ppm = 13.30 (s, 1H), 9.11 (s, 1H), 8.21 (d, J = 8.7, 1H), 7.99 (d, J = 8.7, 1H), 7.87 (d, J = 7.6, 1H), 7.71 (d, J = 9.5, 1H), 7.55 (qd, J = 9.4, 2.7, 2H), 7.20 (d, J = 2.3, 1H), 7.08-6.66 (m, 1H), 6.42 (s, 1H), 3.80-3.75 (m, 4H), 3.49-3.44 (m, 4H)::US9732094, Example 55::US11065253, Example 55	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315630	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315630&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954856	383542375							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616238	OC(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23-28-5-6-33(23)31-21)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SWCDCNCTKFKWOI-UHFFFAOYSA-N	315631	US10172859, Example 63::US10172859, Example 57::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- imidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate::US10172859, Example 56::US9732094, Example 63::US11065253, Example 63	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954834	383542376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616240	OC(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23-28-5-6-33(23)31-21)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SWCDCNCTKFKWOI-UHFFFAOYSA-N	315631	US10172859, Example 63::US10172859, Example 57::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- imidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate::US10172859, Example 56::US9732094, Example 63::US11065253, Example 63	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954834	383542376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616242	COC(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN5O4/c1-35-25(34)21-5-4-20(30-31-21)24(33)16-11-17(19(27)12-18(16)26)23-15-3-2-14(10-22(15)28-13-29-23)32-6-8-36-9-7-32/h2-5,10-13,24,33H,6-9H2,1H3	VYOFGBFGFQHJOU-UHFFFAOYSA-N	315633	US10172859, Example 58::6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid methyl ester1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.23 (d, J = 8.7, 1H), 8.01 (d, J = 8.7, 1H), 7.86 (d, J = 7.6, 1H), 7.70 (d, J = 9.5, 1H), 7.55 (qd, J = 9.4, 2.8, 2H), 7.20 (d, J = 2.4, 1H), 6.94-6.81 (m, 1H), 6.42 (s, 1H), 3.94 (s, 3H), 3.81-3.75 (m, 4H), 3.48-3.42 (m, 4H)::US9732094, Example 58::US11065253, Example 58	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315633	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315633&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954925	383542377							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616244	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	TYZMCDRHMQABIJ-UHFFFAOYSA-N	315618	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- methyl-2H-pyridazin-3- one (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 7.93 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.61- 7.52 (m, 2H), 7.48 (d, J = 9.6, 1H), 7.21 (d, J = 2.4, 1H), 6.93 (d, J = 9.6, 1H), 6.60 (d, J = 4.8, 1H), 5.89 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.59 (s, 3H), 3.48-3.43 (m, 4H)::US10172859, Example 45::US10172859, Example 59::US10172859, Example 44::US9732094, Example 59::US11065253, Example 59	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954795	383542368							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616246	COc1cnc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-13-26-21(12-27-22)24(31)15-2-5-19(25)18(10-15)23-17-4-3-16(11-20(17)28-14-29-23)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WYEVURVICOACEU-UHFFFAOYSA-N	315626	US10172859, Example 60::US10172859, Example 53::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyrazin-2- yl)methanol (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.39-8.38 (m, 1H), 8.23 (d, J = 1.3, 1H), 7.66- 7.61 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 6.30 (d, J = 4.4, 1H), 5.88 (d, J = 4.4, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US10172859, Example 52::US9732094, Example 60::US11065253, Example 60	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954847	383542373							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616248	COc1cnc(cn1)C(O)c1ccc(OC)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25N5O4/c1-32-22-6-3-16(25(31)21-13-27-23(33-2)14-26-21)11-19(22)24-18-5-4-17(12-20(18)28-15-29-24)30-7-9-34-10-8-30/h3-6,11-15,25,31H,7-10H2,1-2H3	LLNFCLAEHDOZRS-UHFFFAOYSA-N	315636	US10172859, Example 61::[4-methoxy-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrazin-2- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.04 (s, 1H), 8.36-8.35 (m, 1H), 8.20 (d, J = 1.4, 1H), 7.53 (dd, J = 8.6, 2.3, 1H), 7.44 (dd, J = 9.4, 2.5, 1H), 7.38 (d, J = 9.4, 1H), 7.35 (d, J = 2.2, 1H), 7.17 (d, J = 8.6, 1H), 7.14 (d, J = 2.5, 1H), 6.13 (d, J = 4.4, 1H), 5.79 (d, J = 4.4, 1H), 3.88 (s, 3H), 3.79-3.75 (m, 4H), 3.66 (s, 3H), 3.43-3.38 (m, 4H)::US9732094, Example 61::US11065253, Example 61	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315636&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954789	383542378							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616250	NC(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20ClFN6O3/c25-17-11-18(26)16(10-15(17)23(33)19-3-4-20(24(27)34)31-30-19)22-14-2-1-13(9-21(14)28-12-29-22)32-5-7-35-8-6-32/h1-4,9-12,23,33H,5-8H2,(H2,27,34)	VTXAYUFQWFXKTM-UHFFFAOYSA-N	315637	US10172859, Example 62::6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid amide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.49 (s, 1H), 8.20 (d, J = 8.7, 1H), 8.00 (d, J = 8.7, 1H), 7.91-7.85 (m, 2H), 7.69 (d, J = 9.5, 1H), 7.59- 7.51 (m, 2H), 7.21 (d, J = 2.2, 1H), 6.84 (d, J = 5.0, 1H), 6.42 (d, J = 5.0, 1H), 3.80-3.75 (m, 4H), 3.48- 3.42 (m, 4H)::US9732094, Example 62::US11065253, Example 62	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315637&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954890	383542379							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616252	OC(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23-28-5-6-33(23)31-21)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SWCDCNCTKFKWOI-UHFFFAOYSA-N	315631	US10172859, Example 63::US10172859, Example 57::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- imidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate::US10172859, Example 56::US9732094, Example 63::US11065253, Example 63	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954834	383542376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616254	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H18Cl2FN5O2/c24-17-11-18(26)16(10-15(17)22(32)21-23(25)28-4-3-27-21)20-14-2-1-13(9-19(14)29-12-30-20)31-5-7-33-8-6-31/h1-4,9-12,22,32H,5-8H2	GLHIUOUYQQLZHP-UHFFFAOYSA-N	315639	US10172859, Example 64::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-chloropyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s, 1H), 8.61 (d, J = 2.4, 1H), 8.49 (d, J = 2.4, 1H), 8.00 (d, J = 7.7, 1H), 7.66 (d, J = 9.5, 1H), 7.64-7.55 (m, 2H), 7.22 (d, J = 2.4, 1H), 6.70 (d, J = 6.0, 1H), 6.42 (d, J = 6.0, 1H), 3.81-3.76 (m, 4H), 3.49-3.44 4H)::US9732094, Example 64::US11065253, Example 64	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315639&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292265	383542380							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616256	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccnn1	InChI=1S/C23H20FN5O2/c24-19-6-3-15(23(30)20-2-1-7-27-28-20)12-18(19)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	HOROSAWYDAWQIJ-UHFFFAOYSA-N	315640	US10172859, Example 65::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (dd, J = 4.9, 1.7, 1H), 9.09 (s, 1H), 7.83 (dd, J = 8.6, 1.7, 1H), 7.72-7.65 (m, 3H), 7.52-7.49 (m, 2H), 7.42- 7.37 (m, 1H), 7.21-7.18 (m, 1H), 6.56 (d, J = 4.3, 1H), 6.12-6.09 (m, 1H), 3.80-3.75 (m, 4H), 3.46- 3.41 (m, 4H)::US9732094, Example 65::US11065253, Example 65	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315640	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315640&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954922	383542381							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616258	COc1cnc(nc1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-17-12-26-24(27-13-17)23(31)15-2-5-20(25)19(10-15)22-18-4-3-16(11-21(18)28-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,23,31H,6-9H2,1H3	FPGGVKYDWGTPRN-UHFFFAOYSA-N	315641	US10172859, Example 67::US10172859, Example 69::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrirnidin-2- yl)methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.53 (s, 2H), 7.70-7.63 (m, 2H), 7.52 (s, 2H), 7.40-7.32 (m, 1H), 7.22-7.15 (m, 1H), 6.06 (d, J = 5.5, 1H), 5.86 (d, J = 5.5, 1H), 3.89 (s, 3H), 3.79- 3.76 (m, 4H), 3.45-3.43 (m, 4H)::US10172859, Example 66::US9732094, Example 69::US11065253, Example 69	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954782	383542382							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616260	COc1cnc(nc1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-17-12-26-24(27-13-17)23(31)15-2-5-20(25)19(10-15)22-18-4-3-16(11-21(18)28-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,23,31H,6-9H2,1H3	FPGGVKYDWGTPRN-UHFFFAOYSA-N	315641	US10172859, Example 67::US10172859, Example 69::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrirnidin-2- yl)methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.53 (s, 2H), 7.70-7.63 (m, 2H), 7.52 (s, 2H), 7.40-7.32 (m, 1H), 7.22-7.15 (m, 1H), 6.06 (d, J = 5.5, 1H), 5.86 (d, J = 5.5, 1H), 3.89 (s, 3H), 3.79- 3.76 (m, 4H), 3.45-3.43 (m, 4H)::US10172859, Example 66::US9732094, Example 69::US11065253, Example 69	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954782	383542382							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616262	CN(C)c1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25FN6O2/c1-31(2)23-8-7-21(29-30-23)25(33)16-3-6-20(26)19(13-16)24-18-5-4-17(14-22(18)27-15-28-24)32-9-11-34-12-10-32/h3-8,13-15,25,33H,9-12H2,1-2H3	LGTMOEJLQNXZRF-UHFFFAOYSA-N	315643	US10172859, Example 68::(6-Dimethylamino- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.65-7.56 (m, 2H), 7.55-7.48 (m, 2H), 7.43- 7.34 (m, 2H), 7.24-7.17 (m, 1H), 7.07 (d, J = 9.4, 1H), 6.27 (d, J = 4.4, 1H), 5.93 (d, J = 4.4, 1H), 3.81- 3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.06 (s, 6H)::US9732094, Example 68::US11065253, Example 68	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315643	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315643&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954889	383542383							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616264	COc1cnc(nc1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-17-12-26-24(27-13-17)23(31)15-2-5-20(25)19(10-15)22-18-4-3-16(11-21(18)28-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,23,31H,6-9H2,1H3	FPGGVKYDWGTPRN-UHFFFAOYSA-N	315641	US10172859, Example 67::US10172859, Example 69::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrirnidin-2- yl)methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.53 (s, 2H), 7.70-7.63 (m, 2H), 7.52 (s, 2H), 7.40-7.32 (m, 1H), 7.22-7.15 (m, 1H), 6.06 (d, J = 5.5, 1H), 5.86 (d, J = 5.5, 1H), 3.89 (s, 3H), 3.79- 3.76 (m, 4H), 3.45-3.43 (m, 4H)::US10172859, Example 66::US9732094, Example 69::US11065253, Example 69	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954782	383542382							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616266	Cc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-2-7-21(29-28-15)24(31)16-3-6-20(25)19(12-16)23-18-5-4-17(13-22(18)26-14-27-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	SCZCGSZBCLOCQY-UHFFFAOYSA-N	315645	US10172859, Example 70::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.72-7.61 (m, 3H), 7.58-7.47 (m, 3H), 7.43- 7.33 (m, 1H), 7.22-7.16 (m, 1H), 6.50 (d, J = 4.0, 1H), 6.07 (d, J = 3.8, 1H), 3.77 (t, J = 5.9, 3.9, 4H), 3.44 (t, J = 4.9, 4H), 2.58 (s, 3H)::US9732094, Example 70::US11065253, Example 70	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315645	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315645&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954787	383542384							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616268	COc1ccc(nn1)[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	IDTQOMSFKJPUNB-UHFFFAOYSA-N	315646	US10172859, Example 71::(R)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.70 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H), 7.53- 7.50 (m, 2H), 7.42-7.37 (m, 1H), 7.22-7.19 (m, 2H), 6.48 (d, J = 4.4, 1H), 6.02 (d, J = 4.4, 1 H), 4.00 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H)::US9732094, Example 71::US11065253, Example 71	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315646	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315646&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711812	383542385							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616270	COc1ccc(nn1)[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	IDTQOMSFKJPUNB-UHFFFAOYSA-N	315647	US10172859, Example 72::(S)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.69 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H), 7.53- 7.50 (m, 2H), 7.41-7.37 (m, 1H), 7.21-7.19 (m, 2H), 6.48 (d, J = 4.4, 1H), 6.02 (d, J = 4.4, 1H), 4.00 (s, 3H), 3.79-3.76 (m, 4H), 3.46-3.42 (m, 4H)::US9732094, Example 72::US11065253, Example 72	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315647	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315647&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954951	383542386							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616272	COC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(OC)nn1	InChI=1S/C25H24FN5O3/c1-32-23-8-7-21(29-30-23)25(33-2)16-3-6-20(26)19(13-16)24-18-5-4-17(14-22(18)27-15-28-24)31-9-11-34-12-10-31/h3-8,13-15,25H,9-12H2,1-2H3	UDKXIJIDLGKASD-UHFFFAOYSA-N	315648	US10172859, Example 73::4-{2-Fluoro-5-[methoxy- (6-methoxy-pyridazin-3- yl)methyl]phenyl}-7- morpholin-4-yl- quinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.69 (d, J = 9.1, 1H), 7.65-7.61 (m, 2H), 7.54- 7.48 (m, 2H), 7.45-7.40 (m, 1H), 7.23 (d, J = 9.2, 1H), 7.21-7.19 (m, 1H), 5.71 (s, 1H), 4.01 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.36 (s, 3H)::US9732094, Example 73::US11065253, Example 73	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315648	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315648&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954802	383542387							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616274	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	IDTQOMSFKJPUNB-UHFFFAOYSA-N	315649	US10172859, Example 74::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.69 (d, J = 9.2, 1H), 7.67-7.61 (m, 2H), 7.54- 7.48 (m, 2H), 7.42-7.36 (m, 1H), 7.22-7.17 (m, 2H), 6.51-6.45 (m, 1H), 6.04-6.00 (m, 1H), 4.00 (s, 3H), 3.80-3.74 (m, 4H), 3.47-3.41 (m, 4H)::US9732094, Example 74::US11065253, Example 256	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315649	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315649&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292267	383542388							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616276	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1C2CCC1COC2)c1ccc(=O)[nH]n1	InChI=1S/C25H22FN5O3/c26-20-6-1-14(25(33)21-7-8-23(32)30-29-21)9-19(20)24-18-5-4-15(10-22(18)27-13-28-24)31-16-2-3-17(31)12-34-11-16/h1,4-10,13,16-17,25,33H,2-3,11-12H2,(H,30,32)	TUGKOSHIUANTCJ-UHFFFAOYSA-N	315650	6-({4-Fluoro-3-[7-(3- oxa-8-aza-bicyclo- [3.2.1]oct-8-yl)- quinazolin-4-yl]phenyl}- hydroxymethyl)-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 12.88- 12.84 (m, 1H), 9.04 (s, 1H), 7.63-7.57 (m, 2H), 7.50-7.45 (m, 2H), 7.44-7.38 (m, 2H), 7.14 (d, J = 2.4, 1H), 6.87 (dd, J = 9.8, 2.2, 1H), 6.42 (d, J = 4.4, 1H), 5.68-5.64 (m, 1H), 4.55-4.46 (m, 2H), 3.69 (d, J = 10.9, 2H), 3.54 (d, J = 10.4, 2H), 2.09-1.94 (m, 4H)::US10172859, Example 75::US9732094, Example 75::US11065253, Example 75	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315650	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315650&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106836	383542389							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616278	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(=O)[nH]n1	InChI=1S/C23H20FN5O3/c24-18-4-1-14(23(31)19-5-6-21(30)28-27-19)11-17(18)22-16-3-2-15(12-20(16)25-13-26-22)29-7-9-32-10-8-29/h1-6,11-13,23,31H,7-10H2,(H,28,30)	LILWOSWCHKKJRS-UHFFFAOYSA-N	315651	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2H- pyridazin-3-one (Ena 2)1H NMR (400 MHz, DMSO-d6) ppm = 12.86 (s, 1H), 9.10 (s, 1H), 7.64-7.58 (m, 2H), 7.55-7.50 (m, 2H), 7.48 (d, J = 9.8, 1H), 7.45-7.38 (m, 1H), 7.23-7.16 (m, 1H), 6.87 (d, J = 9.8, 1H), 6.44 (d, J = 4.3, 1H), 5.70-5.62 (m, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 367::US10172859, Example 76::US9732094, Example 76::US11065253, Example 76	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315651&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106837	383542390							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616280	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(F)cncc1Cl	InChI=1S/C24H19ClF2N4O2/c25-18-11-28-12-20(27)22(18)24(32)14-1-4-19(26)17(9-14)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	UOGVCLMTQITAPC-UHFFFAOYSA-N	315652	(3-Chloro-5-fluoro- pyridin-4-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.58-8.53 (m, 2H), 7.65-7.56 (m, 2H), 7.56- 7.47 (m, 2H), 7.46-7.38 (m, 1H), 7.23-7.17 (m, 1H), 6.65 (d, J = 4.7, 1H), 6.33 (d, J = 4.7, 1H), 3.80- 3.75 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 77::US9732094, Example 77::US11065253, Example 77	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315652	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315652&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292266	383542391							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616282	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 243::US10172859, Example 226::US10172859, Example 259::US10172859, Example 238::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)::US10172859, Example 78::US9732094, Example 259::US11065253, Example 259	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616284	CCOc1cnnc(c1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O3/c1-2-34-18-13-23(30-29-14-18)25(32)16-3-6-21(26)20(11-16)24-19-5-4-17(12-22(19)27-15-28-24)31-7-9-33-10-8-31/h3-6,11-15,25,32H,2,7-10H2,1H3	IQAJYGPAYOWOTI-UHFFFAOYSA-N	315654	(5-Ethoxypyridazin-3- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.84 (d, J = 2.9, 1H), 7.72-7.66 (m, 2H), 7.52-7.49 (m, 2H), 7.41-7.36 (m, 1H), 7.30 (d, J = 2.9, 1H), 7.21-7.18 (m, 1H), 6.52 (d, J = 4.5, 1H), 6.04 (d, J = 4.5, 1H), 4.26-4.16 (m, 2H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 1.34 (t, J = 6.9, 3H).::US10172859, Example 79::US9732094, Example 79::US11065253, Example 79	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315654	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315654&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954937	383542393							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616286	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1C(F)(F)F	InChI=1S/C25H20F4N4O2/c26-20-6-3-15(24(34)23-19(25(27,28)29)2-1-7-30-23)12-18(20)22-17-5-4-16(13-21(17)31-14-32-22)33-8-10-35-11-9-33/h1-7,12-14,24,34H,8-11H2	SJVDCFJVJFVWBU-UHFFFAOYSA-N	315655	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-trifluoro- methylpyridin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.90-8.85 (m, 1H), 8.20 (dd, J = 8.1, 1.6, 1H), 7.63 (dd, J = 6.9, 2.3, 1H), 7.60-7.51 (m, 4H), 7.38 (dd, J = 9.9, 8.6, 1H), 7.21-7.18 (m, 1H), 6.32 (d, J = 6.3, 1H), 6.12 (d, J = 6.0, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 80::US9732094, Example 80::US11065253, Example 80	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315655	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315655&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955010	383542394							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616288	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1OC(F)F	InChI=1S/C25H21F3N4O3/c26-19-6-3-15(24(33)23-21(35-25(27)28)2-1-7-29-23)12-18(19)22-17-5-4-16(13-20(17)30-14-31-22)32-8-10-34-11-9-32/h1-7,12-14,24-25,33H,8-11H2	LBUXFIGKVFCKLV-UHFFFAOYSA-N	315656	(3-Difluoromethoxy- pyridin-2-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.46 (dd, J = 4.6, 1.3, 1H), 7.67-7.64 (m, 1H), 7.62- 7.57 (m, 2H), 7.54-7.49 (m, 2H), 7.42 (dd, J = 8.3, 4.6, 1H), 7.40-7.10 (m, 3H), 6.14-6.07 (m, 2H), 3.81-3.75 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 81::US9732094, Example 81::US11065253, Example 81	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315656	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315656&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292452	383542395							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616290	Cc1nccnc1[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315657	(S)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.44 (s, 2H), 7.64-7.51 (m, 4H), 7.44-7.35 (m, 1H), 7.20 (s, 1H), 6.31 (d, J = 5.5, 1H), 6.09 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.56 (s, 3H).::US10172859, Example 82::US9732094, Example 82::US11065253, Example 82	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315657	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315657&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966367	383542396							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616292	Cc1nccnc1[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315658	(R)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.49 (m, 4H), 7.43-7.34 (m, 1H), 7.19 (s, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.82-3.73 (m, 4H), 3.48-3.40 (m, 4H), 2.55 (s, 3H).::US10172859, Example 83::US9732094, Example 83::US11065253, Example 83	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315658	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315658&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292453	383542397							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616294	Cc1nccnc1[C@H](O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)18-11-17(19(25)12-20(18)26)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	KEMOASSFPWYYBE-UHFFFAOYSA-N	315659	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 8.45 (d, J = 2.5, 1H), 8.39 (dd, J = 2.5, 0.8, 1H), 7.89 (t, J = 8.2, 1H), 7.61 (dd, J = 9.4, 3.2, 1H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.40 (t, J = 10.1, 1H), 7.21 (d, J = 2.4, 1H), 6.39-6.35 (m, 1H), 6.27 (s, 1H), 3.81- 3.75 (m, 4H), 3.49-3.43 (m, 4H), 2.67 (s, 3H).::US10172859, Example 84	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315659	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315659&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292455	383542398							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616296	Cc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)18-11-17(19(25)12-20(18)26)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	KEMOASSFPWYYBE-UHFFFAOYSA-N	315660	US10172859, Example 86::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl) methanol (Ena 1)see racemate::US10172859, Example 85::US9732094, Example 86::US11065253, Example 86	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315660	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315660&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292454	383542399							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616298	Cc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)18-11-17(19(25)12-20(18)26)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	KEMOASSFPWYYBE-UHFFFAOYSA-N	315660	US10172859, Example 86::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl) methanol (Ena 1)see racemate::US10172859, Example 85::US9732094, Example 86::US11065253, Example 86	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315660	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315660&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292454	383542399							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616300	COc1cncnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-21-12-26-13-28-23(21)24(31)15-2-5-19(25)18(10-15)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	PYONFGNQOKWYAY-UHFFFAOYSA-N	315662	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.82 (s, 1H), 8.58 (s, 1H), 7.67-7.61 (m, 2H), 7.55-7.52 (m, 2H), 7.41-7.34 (m, 1H), 7.23- 7.19 (m, 1H), 6.13 (d, J = 6.1, 1H), 6.07 (d, J = 6.2, 1H), 3.95 (s, 3H), 3.83-3.76 (m, 4H), 3.49-3.42 (m, 4H).::US10172859, Example 87::US9732094, Example 87::US11065253, Example 87	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315662&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292457	383542400							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616302	Cc1cnc(C)c(n1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23F2N5O2/c1-14-12-28-15(2)23(31-14)25(33)19-10-18(20(26)11-21(19)27)24-17-4-3-16(9-22(17)29-13-30-24)32-5-7-34-8-6-32/h3-4,9-13,25,33H,5-8H2,1-2H3	CNLAIWPYPBGUKK-UHFFFAOYSA-N	315663	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3,6-dimethyl- pyrazin-2-yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.13 (s, 1H), 8.35 (s, 1H), 7.88 (t, J = 8.2, 1H), 7.61 (dd, J = 9.4, 3.0, 1H), 7.56 (dd, J = 9.5, 2.5, 1H), 7.42 (t, J = 10.2, 1H), 7.23 (d, J = 2.4, 1H), 6.31 (d, J = 5.9, 1H), 6.22 (d, J = 5.6, 1H), 3.85-3.75 (m, 4H), 3.51-3.43 (m, 4H), 2.58 (s, 3H), 2.40 (s, 3H).::US10172859, Example 88::US9732094, Example 88::US11065253, Example 88	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315663	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315663&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292456	383542401							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616304	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H20ClN5O2S/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-10-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	SZNBSUDBRGPGNX-UHFFFAOYSA-N	315664	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s, 1H), 9.04 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.89 (d, J = 2.1, 1H), 7.76 (d, J = 9.4, 1H), 7.73 (dd, J = 8.2, 2.2, 1H), 7.69 (d, J = 8.2, 1H), 7.62 (d, J = 5.6, 1H), 7.47 (dd, J = 9.5, 2.6, 1H), 7.20-7.16 (m, 2H), 6.47 (d, J = 4.9, 1H), 3.81-3.74 (m, 4H), 3.47-3.39 (m, 4H).::US10172859, Example 89::US9732094, Example 89::US11065253, Example 89	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315664&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292652	383542402							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616306	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H19F2N5O2S/c26-19-11-20(27)18(24(33)23-16-3-8-35-25(16)31-13-30-23)10-17(19)22-15-2-1-14(9-21(15)28-12-29-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	CTTOCNUUBHCIRF-UHFFFAOYSA-N	315665	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s, 1H), 9.05 (s,1H), 8.47 (d, J = 5.6, 1H), 7.76 (t, J = 8.0, 1H), 7.61 (d, J = 5.6, 1H), 7.55-7.46 (m, 3H), 7.20- 7.17 (m, 2H), 6.32 (d, J = 4.7, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 90::US9732094, Example 90::US11065253, Example 90	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315665	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315665&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696337	383542403							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616308	Cn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)16-5-8-20(26)19(13-16)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	IVAQITIIINVXDO-UHFFFAOYSA-N	315666	US10172859, Example 375::6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.60-7.56 (m, 2H), 7.55-7.51 (m, 2H), 7.48- 7.43 (m, 1H), 7.40 (dd, J = 9.1, 6.9, 1H), 7.21-7.19 (m, 1H), 6.52 (d, J = 5.3, 1H), 6.36 (dd, J = 9.1, 1.4, 1H), 6.25 (dd, J = 7.0, 1.4, 1H), 5.94 (d, J = 5.1, 1H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.38 (s, 3H).::US10172859, Example 376::US10172859, Example 91::US9732094, Example 91::US11065253, Example 91	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315666&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292653	383542404							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616310	OC(c1ccc(=O)[nH]n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O3/c24-17-11-18(25)16(10-15(17)23(32)19-3-4-21(31)29-28-19)22-14-2-1-13(9-20(14)26-12-27-22)30-5-7-33-8-6-30/h1-4,9-12,23,32H,5-8H2,(H,29,31)	ZSRQBRZKAGNETG-UHFFFAOYSA-N	315667	3-[[2-Chloro-4-fluoro-5- (7-morpholino- quinazolin-4-yl)phenyl]- hydroxymethyl]-1H- pyridazin-6-one1H NMR (400 MHz, DMSO-d6) ppm = 12.89 (d,J = 2.4, 1H), 9.12 (s, 1H), 7.92 (d, J = 7.7, 1H), 7.68(d, J = 9.5, 1H), 7.59-7.55 (m, 2H), 7.53 (d, J = 9.8,1H), 7.21 (d, J = 2.2, 1H), 6.90 (dd, J = 9.8, 2.3, 1H),6.61 (d, J = 5.1, 1H), 5.89 (d, J = 5.1, 1H), 3.81-3.76(m, 4H), 3.48-3.44 (m, 4H)::US10172859, Example 92::US9732094, Example 92::US11065253, Example 92	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315667	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315667&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106838	383542405							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616312	CCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-2-32-23(33)6-5-21(30-32)25(34)17-12-18(20(27)13-19(17)26)24-16-4-3-15(11-22(16)28-14-29-24)31-7-9-35-10-8-31/h3-6,11-14,25,34H,2,7-10H2,1H3	ROTFCYSSIJCDLR-UHFFFAOYSA-N	315668	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-ethyl- 2H-pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.59-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.08-3.95 (m, 2H), 3.81-3.74 (m, 4H),3.49-3.41 (m, 4H), 1.20 (t, J = 7.2, 3H)::US10172859, Example 96::US10172859, Example 97::US10172859, Example 93::US9732094, Example 97::US11065253, Example 97	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292656	383542406							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616314	NCCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24ClFN6O3/c26-19-13-20(27)18(12-17(19)25(35)21-3-4-23(34)33(31-21)6-5-28)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-36-10-8-32/h1-4,11-14,25,35H,5-10,28H2	JVKNZLYEUFZUIQ-UHFFFAOYSA-N	315669	2-(2-Amino-ethyl)-6-{[2- Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.60-7.52(m, 2H), 7.48 (d, J = 9.7, 1H), 7.21 (d, J = 2.2, 1H),6.94 (d, J = 9.6, 1H), 6.72-6.57 (m, 1H), 5.91 (s,1H), 4.10-3.96 (m, 2H), 3.82-3.73 (m, 4H), 3.48-3.43 (m, 4H), 2.88 (t, J = 6.6, 2H)::US10172859, Example 94::US9732094, Example 94::US11065253, Example 94	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315669	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315669&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954771	383542407							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616316	OC(c1ccc(=O)n(n1)C1CC1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O3/c27-20-13-21(28)19(12-18(20)26(35)22-5-6-24(34)33(31-22)15-1-2-15)25-17-4-3-16(11-23(17)29-14-30-25)32-7-9-36-10-8-32/h3-6,11-15,26,35H,1-2,7-10H2	SFQDWLSJUWKEID-UHFFFAOYSA-N	315670	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- cyclopropyl-2H- pyridazin-3-one1H NMR (400 MHz, Methylenchlorid-d2) ppm = 9.04(s, 1H), 7.71 (d, J = 7.6, 1H), 7.49 (dd, J = 9.3, 3.5,1H), 7.26-7.20 (m, 2H), 7.18-7.14 (m, 2H), 6.74(d, J = 9.6, 1H), 5.97 (s, 1H), 4.03-3.94 (m, 1H),3.82-3.74 (m, 4H), 3.39-3.31 (m, 4H), 0.98-0.82(m, 4H)::US10172859, Example 95::US9732094, Example 95::US11065253, Example 95	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315670	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315670&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954967	383542408							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616318	CCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-2-32-23(33)6-5-21(30-32)25(34)17-12-18(20(27)13-19(17)26)24-16-4-3-15(11-22(16)28-14-29-24)31-7-9-35-10-8-31/h3-6,11-14,25,34H,2,7-10H2,1H3	ROTFCYSSIJCDLR-UHFFFAOYSA-N	315668	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-ethyl- 2H-pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.59-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.08-3.95 (m, 2H), 3.81-3.74 (m, 4H),3.49-3.41 (m, 4H), 1.20 (t, J = 7.2, 3H)::US10172859, Example 96::US10172859, Example 97::US10172859, Example 93::US9732094, Example 97::US11065253, Example 97	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292656	383542406							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616320	CCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-2-32-23(33)6-5-21(30-32)25(34)17-12-18(20(27)13-19(17)26)24-16-4-3-15(11-22(16)28-14-29-24)31-7-9-35-10-8-31/h3-6,11-14,25,34H,2,7-10H2,1H3	ROTFCYSSIJCDLR-UHFFFAOYSA-N	315668	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-ethyl- 2H-pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.59-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.08-3.95 (m, 2H), 3.81-3.74 (m, 4H),3.49-3.41 (m, 4H), 1.20 (t, J = 7.2, 3H)::US10172859, Example 96::US10172859, Example 97::US10172859, Example 93::US9732094, Example 97::US11065253, Example 97	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292656	383542406							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616322	NC(=O)Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O4/c26-18-11-19(27)17(10-16(18)25(36)20-3-4-23(35)33(31-20)12-22(28)34)24-15-2-1-14(9-21(15)29-13-30-24)32-5-7-37-8-6-32/h1-4,9-11,13,25,36H,5-8,12H2,(H2,28,34)	BXOINBJDZSONOX-UHFFFAOYSA-N	315673	2-(3-{[2-Chloro-4- fluoro-5-(7-morpholin- 4-ylquinazolin-4-yl)- phenyl]hydroxymethyl}- 6-oxo-6H-pyridazin-1- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H),7.93 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H), 7.58 (dd,J = 9.4, 3.0, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.51-7.44 (m, 2H), 7.21 (d, J = 2.4, 1H), 7.15 (s, 1H),6.94 (d, J = 9.6, 1H), 6.62 (d, J = 4.8, 1H), 5.89 (d,J = 4.8, 1H), 4.61-4.51 (m, 2H), 3.81-3.75 (m, 4H),3.48-3.42 (m, 4H)::US10172859, Example 98::US9732094, Example 98::US11065253, Example 98	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315673	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315673&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954848	383542409							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616324	OCCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O4/c26-19-13-20(27)18(12-17(19)25(35)21-3-4-23(34)32(30-21)5-8-33)24-16-2-1-15(11-22(16)28-14-29-24)31-6-9-36-10-7-31/h1-4,11-14,25,33,35H,5-10H2	HPUBJROQDSYMAY-UHFFFAOYSA-N	315674	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-(2- hydroxy-ethyl)-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.60-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.75 (t, J = 5.8, 1H), 4.11-4.00 (m, 2H),3.82-3.74 (m, 4H), 3.65 (q, J = 6.2, 2H), 3.49-3.42::US10172859, Example 99::US9732094, Example 99::US11065253, Example 99	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315674	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315674&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954862	383542410							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616326	OC(c1ccc(OC2COC2)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O4/c27-20-11-21(28)19(10-18(20)26(34)22-3-4-24(32-31-22)37-16-12-36-13-16)25-17-2-1-15(9-23(17)29-14-30-25)33-5-7-35-8-6-33/h1-4,9-11,14,16,26,34H,5-8,12-13H2	SRYMLVUNMNZEHF-UHFFFAOYSA-N	315675	[2-Chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-[6-(oxetan-3-yloxy)pyridazin-3-yl]methanol ::US10172859, Example 100::US9732094, Example 100::US11065253, Example 100	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315675	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315675&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292655	383542411							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616328	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US9732094, Example 104::US11065253, Example 104	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616330	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US9732094, Example 104::US11065253, Example 104	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616332	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US9732094, Example 104::US11065253, Example 104	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616334	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US9732094, Example 104::US11065253, Example 104	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616336	OCCOc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O4/c26-20-4-1-16(24(33)23-25(35-12-9-32)28-6-5-27-23)13-19(20)22-18-3-2-17(14-21(18)29-15-30-22)31-7-10-34-11-8-31/h1-6,13-15,24,32-33H,7-12H2	KVAPMCUPBPNTHD-UHFFFAOYSA-N	315680	2-(3-{[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl- oxy)ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.19 (d, J = 2.8, 1H), 8.12 (d, J = 2.8, 1H),7.70-7.64 (m, 2H), 7.54-7.51 (m, 2H), 7.38-7.33 (m, 1H), 7.21-7.19 (m, 1H), 6.14 (d,J = 5.9, 1H), 6.00 (d, J = 6.0, 1H), 4.86 (t, J = 5.7,1H), 4.34-4.30 (m, 2H), 3.80-3.75 (m, 4H),3.74-3.69 (m, 2H), 3.46-3.42 (m, 4H)::US10172859, Example 105::US9732094, Example 105::US11065253, Example 105	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315680&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954969	383542413							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616338	OCCNc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25FN6O3/c26-20-4-1-16(24(34)23-25(29-7-10-33)28-6-5-27-23)13-19(20)22-18-3-2-17(14-21(18)30-15-31-22)32-8-11-35-12-9-32/h1-6,13-15,24,33-34H,7-12H2,(H,28,29)	YVVAIAKPXYKXCT-UHFFFAOYSA-N	315681	2-(3-{[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl- amino)ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.91 (d, J = 2.7, 1H), 7.67 (d, J = 2.8, 1H),7.63-7.58 (m, 2H), 7.55-7.49 (m, 2H), 7.41-7.35 (m, 1H), 7.20 (d, J = 2.0, 1H), 6.82-6.75(m, 2H), 5.91 (d, J = 4.2, 1H), 4.74 (t, J = 5.1, 1H),3.82-3.73 (m, 4H), 3.60-3.45 (m, 8H)::US10172859, Example 106::US9732094, Example 106::US11065253, Example 106	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315681	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315681&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954909	383542414							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616340	OC(c1ccc(OCCC#N)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H22ClFN6O3/c27-20-14-21(28)19(13-18(20)26(35)22-4-5-24(33-32-22)37-9-1-6-29)25-17-3-2-16(12-23(17)30-15-31-25)34-7-10-36-11-8-34/h2-5,12-15,26,35H,1,7-11H2	ZOBQEXZTIUCXDW-UHFFFAOYSA-N	315682	3-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.95 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H),7.59 (dd, J = 9.4, 3.2, 1H), 7.55-7.49 (m, 2H),7.21 (d, J = 2.4, 1H), 6.99 (d, J = 9.6, 1H), 6.67(d, J = 4.9, 1H), 5.92 (d, J = 4.9, 1H), 4.31-4.17(m, 2H), 3.81-3.75 (m, 4H), 3.49-3.42 (m,4H), 2.99-2.88 (m, 2H)::US10172859, Example 107::US9732094, Example 107::US11065253, Example 107	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315682	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315682&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955015	383542415							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616342	CSc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O2S/c1-34-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	QGUGXNKWEKXBMQ-UHFFFAOYSA-N	315683	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methyl- sulfanylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.90 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H),7.66-7.60 (m, 2H), 7.60-7.56 (m, 1H), 7.54(dd, J = 9.4, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.68(s, 1H), 6.25 (s, 1H), 3.80-3.76 (m, 4H), 3.47-3.43 (m, 4H), 2.61 (s, 3H)::US10172859, Example 108::US9732094, Example 108::US11065253, Example 108	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315683&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292847	383542416							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616344	COc1cc(C)c(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-14-9-22(34-2)30-31-23(14)25(33)17-11-18(20(27)12-19(17)26)24-16-4-3-15(10-21(16)28-13-29-24)32-5-7-35-8-6-32/h3-4,9-13,25,33H,5-8H2,1-2H3	USOUBBMUUGTPON-UHFFFAOYSA-N	315684	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- 4-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 7.99 (d, J = 7.8, 1H), 7.67-7.61 (m, 2H),7.57 (dd, J = 9.4, 2.6, 1H), 7.23 (d, J = 2.5, 1H),7.10 (d, J = 1.1, 1H), 6.42 (d, J = 6.4, 1H), 6.25(d, J = 6.3, 1H), 3.96 (s, 3H), 3.82-3.75 (m,4H), 3.50-3.42 (m, 4H), 2.49-2.46 (m, 3H)::US10172859, Example 109::US9732094, Example 109::US11065253, Example 109	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315684	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315684&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954913	383542417							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616346	COc1nnc(cc1C)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-14-9-22(30-31-25(14)34-2)24(33)17-11-18(20(27)12-19(17)26)23-16-4-3-15(10-21(16)28-13-29-23)32-5-7-35-8-6-32/h3-4,9-13,24,33H,5-8H2,1-2H3	ZTLYNAMLFWWNRW-UHFFFAOYSA-N	315685	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- 5-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.8, 1H), 7.66 (d, J = 9.6, 1H),7.59 (dd, J = 9.4, 3.3, 1H), 7.56-7.52 (m, 2H),7.21 (d, J = 2.4, 1H), 6.54 (d, J = 4.9, 1H), 6.18(d, J = 4.9, 1H), 4.02 (s, 3H), 3.80-3.75 (m,4H), 3.48-3.43 (m, 4H), 2.17 (d, J = 1.0, 3H)::US10172859, Example 110::US9732094, Example 110::US11065253, Example 110	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315685	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315685&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954772	383542418							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616348	NC(=O)COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O4/c26-18-11-19(27)17(10-16(18)25(35)20-3-4-23(32-31-20)37-12-22(28)34)24-15-2-1-14(9-21(15)29-13-30-24)33-5-7-36-8-6-33/h1-4,9-11,13,25,35H,5-8,12H2,(H2,28,34)	SDAGDBFBEANYBV-UHFFFAOYSA-N	315686	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.92 (d, J = 7.7, 1H), 7.74 (d, J = 9.1, 1H),7.66 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H),7.57-7.49 (m, 2H), 7.27 (d, J = 9.1, 1H), 7.23-7.16 (m, 2H), 6.63 (d, J = 5.0, 1H), 6.23 (d,J = 5.0, 1H), 4.81 (s, 2H), 3.81-3.75 (m, 4H),3.49-3.43 (m, 4H)::US10172859, Example 111::US9732094, Example 111::US11065253, Example 111	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315686&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954830	383542419							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616350	COCCOc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H25ClFN5O4/c1-35-10-11-37-24-5-4-22(31-32-24)26(34)18-13-19(21(28)14-20(18)27)25-17-3-2-16(12-23(17)29-15-30-25)33-6-8-36-9-7-33/h2-5,12-15,26,34H,6-11H2,1H3	VEXMWYKCSKRUDC-UHFFFAOYSA-N	315687	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-[6-(2- methoxyethoxy)- pyridazin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H),7.54 (dd, J = 9.5, 2.5, 1H), 7.25-7.19 (m, 2H),6.61 (d, J = 5.0, 1H), 6.23 (d, J = 5.0, 1H), 4.54-4.50 (m, 2H), 3.80-3.75 (m, 4H), 3.71-3.67(m, 2H), 3.48-3.43 (m, 4H), 3.29 (s, 3H)::US10172859, Example 112::US9732094, Example 112::US11065253, Example 112	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315687&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955001	383542420							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616352	OC(c1ccc(OCC(O)=O)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN5O5/c26-18-11-19(27)17(10-16(18)25(35)20-3-4-22(31-30-20)37-12-23(33)34)24-15-2-1-14(9-21(15)28-13-29-24)32-5-7-36-8-6-32/h1-4,9-11,13,25,35H,5-8,12H2,(H,33,34)	JNGCYUIWAFFJPM-UHFFFAOYSA-N	315688	(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetic acid1H NMR (500 MHz, DMSO-d6) ppm = 12.91 (s,1H), 9.12 (s, 1H), 7.92 (d, J = 7.7, 1H), 7.75 (d,J = 9.1, 1H), 7.66 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4,3.3, 1H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.31 (d,J = 9.1, 1H), 7.21 (d, J = 2.4, 1H), 6.66 (s, 1H),6.23 (s, 1H), 4.97 (s, 2H), 3.81-3.75 (m, 4H),3.48-3.43 (m, 4H)::US10172859, Example 113::US9732094, Example 113::US11065253, Example 113	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315688	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315688&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954993	383542421							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616354	COC(=O)COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O5/c1-36-24(34)13-38-23-5-4-21(31-32-23)26(35)17-11-18(20(28)12-19(17)27)25-16-3-2-15(10-22(16)29-14-30-25)33-6-8-37-9-7-33/h2-5,10-12,14,26,35H,6-9,13H2,1H3	GLBIKYWGGXTOCO-UHFFFAOYSA-N	315690	(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetic acid methyl ester1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.92 (d, J = 7.7, 1H), 7.77 (d, J = 9.1, 1H),7.67 (d, J = 9.5, 1H), 7.59 (dd, J = 9.3, 3.2, 1H),7.57-7.51 (m, 1H), 7.35 (d, J = 9.1, 1H), 7.23-7.19 (m, 1H), 6.62 (s, 1H), 6.23 (s, 1H), 5.07(s, 2H), 3.81-3.75 (m, 4H), 3.67 (s, 3H), 3.49-3.44 (m, 4H)::US10172859, Example 114::US9732094, Example 114::US11065253, Example 114	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315690	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315690&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954756	383542423							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616356	OC(c1ccc(OCC(F)(F)F)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClF4N5O3/c26-18-11-19(27)17(10-16(18)24(36)20-3-4-22(34-33-20)38-12-25(28,29)30)23-15-2-1-14(9-21(15)31-13-32-23)35-5-7-37-8-6-35/h1-4,9-11,13,24,36H,5-8,12H2	XBIFOHKQPCJZBA-UHFFFAOYSA-N	315691	US10172859, Example 115::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-[6-(2,2,2- trifluoroethoxy)- pyridazin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.91 (d, J = 7.7, 1H), 7.81 (d, J = 9.2, 1H),7.66 (d, J = 9.5, 1H), 7.60-7.52 (m, 2H), 7.41(d, J = 9.1, 1H), 7.20 (d, J = 2.3, 1H), 6.72 (d,J = 5.0, 1H), 6.26 (d, J = 4.5, 1H), 5.22-5.08 (m,2H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)::US9732094, Example 115::US11065253, Example 115	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315691	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315691&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954817	383542424							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616358	OCCOc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O4/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23(31-30-21)36-10-7-33)24-16-2-1-15(11-22(16)28-14-29-24)32-5-8-35-9-6-32/h1-4,11-14,25,33-34H,5-10H2	HJYNFJSAPISPIC-UHFFFAOYSA-N	315692	US10172859, Example 116::2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.71-7.64 (m, 2H),7.61-7.51 (m, 2H), 7.23-7.17 (m, 2H), 6.60(d, J = 5.0, 1H), 6.22 (d, J = 5.0, 1H), 4.84 (t,J = 5.5, 1H), 4.44-4.39 (m, 2H), 3.81-3.76 (m,4H), 3.74 (q, J = 5.4, 2H), 3.48-3.43 (m, 4H)::US9732094, Example 116::US11065253, Example 116	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315692	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315692&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954855	383542425							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616360	Nc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN6O2/c24-17-11-18(25)16(10-15(17)22(32)21-23(26)28-4-3-27-21)20-14-2-1-13(9-19(14)29-12-30-20)31-5-7-33-8-6-31/h1-4,9-12,22,32H,5-8H2,(H2,26,28)	NLBRAVXIOQVDEK-UHFFFAOYSA-N	315693	US10172859, Example 117::(3-Amino-pyrazin-2- yl)-[2-chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.14 (s,1H), 7.91 (d, J = 7.8, 1H), 7.87 (d, J = 2.7, 1H),7.67-7.55 (m, 4H), 7.21 (d, J = 2.5, 1H), 6.41(s, 3H), 6.09 (s, 1H), 3.81-3.75 (m, 4H), 3.50-3.45 (m, 4H)::US9732094, Example 117::US11065253, Example 117	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315693	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315693&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954853	383542426							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616362	OC(c1ccc(nn1)C#N)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H18ClFN6O2/c25-19-11-20(26)18(10-17(19)24(33)21-4-1-14(12-27)30-31-21)23-16-3-2-15(9-22(16)28-13-29-23)32-5-7-34-8-6-32/h1-4,9-11,13,24,33H,5-8H2	PBJNYJLKFRLXQN-UHFFFAOYSA-N	315694	US10172859, Example 118::6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazine- 3-carbonitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.36 (d, J = 8.7, 1H), 8.13 (d, J = 8.7, 1H),7.86 (d, J = 7.6, 1H), 7.71 (d, J = 9.5, 1H), 7.55(qd, J = 9.4, 2.7, 2H), 7.21 (d, J = 2.3, 1H), 6.96(d, J = 4.9, 1H), 6.43 (d, J = 4.9, 1H), 3.80-3.76(m, 4H), 3.48-3.43 (m, 4H)::US9732094, Example 118::US11065253, Example 118	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315694	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315694&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954940	383542427							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616364	OC(c1ccc(OCC#N)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O3/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23(32-31-21)36-8-5-28)24-16-2-1-15(11-22(16)29-14-30-24)33-6-9-35-10-7-33/h1-4,11-14,25,34H,6-10H2	VMNGDZCHPAYWBU-UHFFFAOYSA-N	315695	US10172859, Example 119::(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetonitrile1H NMR (400 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.93 (d, J = 7.7, 1H), 7.85 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.60 (dd, J = 9.4, 3.3, 1H),7.54 (dd, J = 9.4, 2.5, 1H), 7.40 (d, J = 9.1, 1H),7.21 (d, J = 2.4, 1H), 6.72 (d, J = 5.0, 1H), 6.28(d, J = 4.8, 1H), 5.38 (s, 2H), 3.81-3.75 (m,::US9732094, Example 119::US11065253, Example 119	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315695	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315695&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292848	383542428							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616366	COc1ccc(cc1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23F2N3O3/c1-33-18-5-2-16(3-6-18)26(32)21-13-20(22(27)14-23(21)28)25-19-7-4-17(12-24(19)29-15-30-25)31-8-10-34-11-9-31/h2-7,12-15,26,32H,8-11H2,1H3	IZHMEJPZUSRPSC-UHFFFAOYSA-N	315696	US10172859, Example 120::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- methoxyphenyl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.61-7.47 (m, 3H), 7.36-7.30 (m, 2H),7.27 (t, J = 9.1, 1H), 7.20 (d, J = 2.3, 1H), 6.93-6.87 (m, 2H), 6.18 (d, J = 4.6, 1H), 6.14 (d,J = 4.6, 1H), 3.81-3.75 (m, 4H), 3.73 (s, 3H),3.48-3.41 (m, 4H)::US9732094, Example 120::US11065253, Example 120	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315696	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315696&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696345	383542429							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616368	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(OC(F)F)nn1	InChI=1S/C24H20F3N5O3/c25-18-4-1-14(23(33)19-5-6-21(31-30-19)35-24(26)27)11-17(18)22-16-3-2-15(12-20(16)28-13-29-22)32-7-9-34-10-8-32/h1-6,11-13,23-24,33H,7-10H2	RFKLNHCZEVTKQI-UHFFFAOYSA-N	315697	US10172859, Example 121::(6-Difluoro- methoxy- pyridazin-3-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.96 (d, J = 9.1, 1H), 7.73-7.63 (m, 2H),7.57-7.47 (m, 3H), 7.46-7.31 (m, 1H), 7.22-7.16 (m, 1H), 6.63 (d, J = 4.4, 1H), 6.10 (d,J = 4.4, 1H), 3.81-3.75 (m, 4H), 3.47-3.41(m, 4H)::US9732094, Example 121::US11065253, Example 121	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315697	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315697&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696306	383542430							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616370	COc1ccc(nn1)C(O)(C#C)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H21ClFN5O3/c1-3-26(34,23-6-7-24(35-2)32-31-23)19-13-18(21(28)14-20(19)27)25-17-5-4-16(12-22(17)29-15-30-25)33-8-10-36-11-9-33/h1,4-7,12-15,34H,8-11H2,2H3	JGPODTAIHNTKRI-UHFFFAOYSA-N	315698	US10172859, Example 122::1-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-(6- methoxy- pyridazin-3-yl)- prop-2-yn-1-ol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.28 (d, J = 7.7, 1H), 7.96 (d, J = 9.2, 1H),7.69-7.63 (m, 2H), 7.59 (dd, J = 9.5, 2.5, 1H),7.50 (s, 1H), 7.30 (d, J = 9.2, 1H), 7.23 (d,J = 2.5, 1H), 4.02 (s, 3H), 3.94 (s, 1H), 3.81-3.76 (m, 4H), 3.50-3.44 (m, 4H)::US9732094, Example 122::US11065253, Example 122	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315698	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315698&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696299	383542431							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616372	COc1ccc(nn1)C(O)(C(F)F)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClF3N5O3/c1-36-22-5-4-21(32-33-22)25(35,24(28)29)17-11-16(19(27)12-18(17)26)23-15-3-2-14(10-20(15)30-13-31-23)34-6-8-37-9-7-34/h2-5,10-13,24,35H,6-9H2,1H3	BKJXFQFDFKAFDJ-UHFFFAOYSA-N	315699	US10172859, Example 123::1-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2,2- difluoro-1-(6- methoxy- pyridazin-3-yl)- ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.15 (s,1H), 8.17 (d, J = 7.7, 1H), 7.67-7.61 (m, 3H),7.57 (dd, J = 9.5, 2.5, 1H), 7.32 (s, 1H), 7.26(d, 1H), 7.25-7.22 (m, 1H), 7.22-6.96 (m,2H), 4.05 (s, 3H), 3.81-3.75 (m, 4H), 3.50-3.45 (m, 4H).::US9732094, Example 123::US11065253, Example 123	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315699	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315699&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954917	383542432							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616374	COc1ccc(C(O)c2cc(c(F)cc2F)-c2ncnc3cc(ccc23)N2CCOCC2)c(F)c1	InChI=1S/C26H22F3N3O3/c1-34-16-3-5-17(21(27)11-16)26(33)20-12-19(22(28)13-23(20)29)25-18-4-2-15(10-24(18)30-14-31-25)32-6-8-35-9-7-32/h2-5,10-14,26,33H,6-9H2,1H3	DRCQLIDBEVYMKC-UHFFFAOYSA-N	315700	US10172859, Example 124::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(2-fluoro- 4-methoxy- phenyl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.70 (t, J = 8.8, 1H), 7.62-7.44 (m, 3H),7.25 (t, J = 9.2, 1H), 7.20 (d, J = 2.4, 1H), 6.82(dd, J = 8.6, 2.5, 1H), 6.74 (dd, J = 12.6, 2.5,1H), 6.34 (d, J = 4.6, 1H), 6.28 (d, J = 4.6, 1H),3.82-3.71 (m, 7H), 3.49-3.41 (m, 4H)::US9732094, Example 124::US11065253, Example 124	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315700	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315700&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966369	383542433							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616376	COc1ccc(nn1)C(C)(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-25(33,22-5-6-23(34-2)31-30-22)18-12-17(20(27)13-19(18)26)24-16-4-3-15(11-21(16)28-14-29-24)32-7-9-35-10-8-32/h3-6,11-14,33H,7-10H2,1-2H3	UAARYCWPHSSNIM-UHFFFAOYSA-N	315701	US10172859, Example 125::1-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-(6- methoxy- pyridazin-3-yl)- ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.15 (s,1H), 8.20 (d, J = 7.9, 1H), 7.67 (dd, J = 9.4, 3.4,1H), 7.60-7.54 (m, 3H), 7.23 (d, J = 2.5, 1H),7.18 (d, J = 9.2, 1H), 6.39 (s, 1H), 4.03 (s, 3H),3.82-3.75 (m, 4H), 3.49-3.45 (m, 4H), 2.02(s, 3H)::US9732094, Example 125::US11065253, Example 125	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315701&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954946	383542434							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616378	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c1-31-18-3-2-16(27-28-18)21(30)12-8-13(15(24)9-14(12)23)20-22-17(25-11-26-20)10-19(33-22)29-4-6-32-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	PIPPQGLJMKVPBT-UHFFFAOYSA-N	315702	US10172859, Example 127::US10172859, Example 128::[2-Chloro-4-fluoro- 5-(6-morpholin-4- ylthieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 8.90 (s,1H), 8.00 (d, J = 7.9, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 10.0, 1H), 7.22 (d, J = 9.2, 1H), 6.62(d, J = 4.9, 1H), 6.54 (s, 1H), 6.22 (d, J = 4.9,1H), 3.99 (s, 3H), 3.77-3.72 (m, 4H), 3.45-3.39 (m, 4H)::US10172859, Example 126::US9732094, Example 128::US11065253, Example 128	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315702&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966370	383542435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616380	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c1-31-18-3-2-16(27-28-18)21(30)12-8-13(15(24)9-14(12)23)20-22-17(25-11-26-20)10-19(33-22)29-4-6-32-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	PIPPQGLJMKVPBT-UHFFFAOYSA-N	315702	US10172859, Example 127::US10172859, Example 128::[2-Chloro-4-fluoro- 5-(6-morpholin-4- ylthieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 8.90 (s,1H), 8.00 (d, J = 7.9, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 10.0, 1H), 7.22 (d, J = 9.2, 1H), 6.62(d, J = 4.9, 1H), 6.54 (s, 1H), 6.22 (d, J = 4.9,1H), 3.99 (s, 3H), 3.77-3.72 (m, 4H), 3.45-3.39 (m, 4H)::US10172859, Example 126::US9732094, Example 128::US11065253, Example 128	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315702&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966370	383542435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616382	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c1-31-18-3-2-16(27-28-18)21(30)12-8-13(15(24)9-14(12)23)20-22-17(25-11-26-20)10-19(33-22)29-4-6-32-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	PIPPQGLJMKVPBT-UHFFFAOYSA-N	315702	US10172859, Example 127::US10172859, Example 128::[2-Chloro-4-fluoro- 5-(6-morpholin-4- ylthieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 8.90 (s,1H), 8.00 (d, J = 7.9, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 10.0, 1H), 7.22 (d, J = 9.2, 1H), 6.62(d, J = 4.9, 1H), 6.54 (s, 1H), 6.22 (d, J = 4.9,1H), 3.99 (s, 3H), 3.77-3.72 (m, 4H), 3.45-3.39 (m, 4H)::US10172859, Example 126::US9732094, Example 128::US11065253, Example 128	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315702	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315702&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966370	383542435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616384	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 244::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 262::US10172859, Example 129::US9732094, Example 262::US11065253, Example 262	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616386	COc1ccc(nn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-20(29-30-22)24(32)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	FWMURCSQJAVESQ-UHFFFAOYSA-N	315707	US10172859, Example 131::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate::US10172859, Example 130::US9732094, Example 131::US11065253, Example 131	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315707	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315707&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954810	383542438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616388	COc1ccc(nn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-20(29-30-22)24(32)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	FWMURCSQJAVESQ-UHFFFAOYSA-N	315707	US10172859, Example 131::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate::US10172859, Example 130::US9732094, Example 131::US11065253, Example 131	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315707	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315707&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954810	383542438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616390	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1nc(Cl)nc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20Cl2FN5O3/c1-34-21-5-4-19(30-31-21)23(33)15-11-16(18(27)12-17(15)25)22-14-3-2-13(32-6-8-35-9-7-32)10-20(14)28-24(26)29-22/h2-5,10-12,23,33H,6-9H2,1H3	ULPNOVCLDUJYMN-UHFFFAOYSA-N	315711	US10172859, Example 132::[2-Chloro-5-(2- chloro-7- morpholin-4-yl- quinazolin-4-yl)-4- fluorophenyl]-(6- methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 7.94 (d,J = 7.7, 1H), 7.72-7.65 (m, 2H), 7.63-7.49(m, 2H), 7.21 (d, J = 9.1, 1H), 7.15 (d, J = 2.4,1H), 6.22 (s, 1H), 4.00 (s, 3H), 3.79-3.73(m, 4H), 3.53-3.47 (m, 4H)::US9732094, Example 132::US11065253, Example 132	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315711	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315711&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966371	383542441							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616392	CN(C)CCOc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H29FN6O3/c1-33(2)9-14-37-25-8-7-23(31-32-25)27(35)18-3-6-22(28)21(15-18)26-20-5-4-19(16-24(20)29-17-30-26)34-10-12-36-13-11-34/h3-8,15-17,27,35H,9-14H2,1-2H3	XHNGNRHWZGKQQA-UHFFFAOYSA-N	315712	US10172859, Example 133::[6-(2-Dimethyl- amino-ethoxy)- pyridazin-3-yl]-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.69 (d, J = 9.2, 1H), 7.67-7.61 (m, 2H),7.55-7.47 (m, 2H), 7.44-7.36 (m, 1H), 7.24-7.15 (m, 2H), 6.49 (d, J = 4.0, 1H), 6.04-5.98 (m, 1H), 4.56-4.41 (m, 2H), 3.80-3.74(m, 4H), 3.47-3.41 (m, 4H), 2.64 (t, J = 5.8,2H), 2.19 (s, 6H)::US9732094, Example 133::US11065253, Example 133	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315712	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315712&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954921	383542442							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616394	CCOc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O3/c1-2-34-23-8-7-21(29-30-23)25(32)16-3-6-20(26)19(13-16)24-18-5-4-17(14-22(18)27-15-28-24)31-9-11-33-12-10-31/h3-8,13-15,25,32H,2,9-12H2,1H3	LEDWCZDSFAXZKY-UHFFFAOYSA-N	315713	US10172859, Example 134::(6-Ethoxy- pyridazin-3-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.68 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H),7.53-7.50 (m, 2H), 7.43-7.35 (m, 1H), 7.21-7.19 (m, 1H), 7.17 (d, J = 9.1, 1H), 6.47 (d,J = 4.4, 1H), 6.01 (d, J = 4.3, 1H), 4.52-4.38(m, 2H), 3.82-3.73 (m, 4H), 3.46-3.41 (m,4H), 1.36 (t, J = 7.0, 3H)::US9732094, Example 134::US11065253, Example 134	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315713	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315713&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954942	383542443							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616396	COc1ccc(nn1)[C@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315714	US10172859, Example 135::(R)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.62-7.51 (m, 2H), 7.24-7.18 (m, 2H), 6.61 (d, J = 4.8, 1H), 6.23 (d,J = 4.8, 1H), 4.00 (s, 3H), 3.81-3.75 (m, 4H),3.48-3.42 (m, 4H)::US9732094, Example 135::US11065253, Example 135	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315714	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315714&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955008	383542444							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616398	COc1ccc(nn1)[C@@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315715	US10172859, Example 136::(S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 9.5, 1H), 7.61-7.52 (m, 2H), 7.24-7.19 (m, 2H), 6.61 (d, J = 5.0, 1H), 6.23 (d,J = 4.9, 1H), 4.00 (s, 3H), 3.81-3.75 (m, 4H),3.48-3.43 (m, 4H)::US9732094, Example 136::US11065253, Example 136	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315715	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315715&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292849	383542445							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616400	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 244::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 262::US10172859, Example 129::US9732094, Example 262::US11065253, Example 262	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616402	CC(O)(c1nccs1)c1cncc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H21N5O2S/c1-22(28,21-24-4-9-30-21)16-10-15(12-23-13-16)20-18-3-2-17(11-19(18)25-14-26-20)27-5-7-29-8-6-27/h2-4,9-14,28H,5-8H2,1H3	WZGXFUTUWYUZBK-UHFFFAOYSA-N	315717	1-[5-(7-Morpholin-4-ylquinazolin-4-yl)pyridin-3-yl]-1-thiazol-2-ylethanol (EXAMPLE 138)::US10172859, Example 151::US10172859, Example 152::US10172859, Example 138::US9732094, Example 152::US11065253, Example 152	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315717&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696290	383542446							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616404	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)C1=CCOCC1 |t:28|	InChI=1S/C23H18FN3O2S/c24-19-4-2-16(22(28)23-25-7-10-30-23)11-18(19)21-17-3-1-15(12-20(17)26-13-27-21)14-5-8-29-9-6-14/h1-5,7,10-13,22,28H,6,8-9H2	PNOUMLBQVUAYPF-UHFFFAOYSA-N	315718	US10172859, Example 139::{3-[7-(3,6-Dihydro-2H-pyran-4-yl)quinazolin-4-yl]-4-fluorophenyl}thiazol-2-ylmethanol ::US9732094, Example 139::US11065253, Example 139	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315718	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315718&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696701	383542447							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616406	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-16-2-1-13(20(28)21-23-3-8-30-21)9-14(16)19-15-11-24-18(10-17(15)25-12-26-19)27-4-6-29-7-5-27/h1-3,8-12,20,28H,4-7H2	XCXKEQWXYBNSEE-UHFFFAOYSA-N	315719	US10172859, Example 140::[4-Fluoro-3-(7-morpholin-4-ylpyrido[4,3-d}pyrimidin-4-yl)phenyl]thiazol-2-ylmethanol ::US9732094, Example 140::US11065253, Example 140	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315719&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696258	383542448							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616408	OCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c23-16-6-17(24)14(5-13(16)21(31)22-28-12(9-30)10-33-22)20-15-8-25-19(7-18(15)26-11-27-20)29-1-3-32-4-2-29/h5-8,10-11,21,30-31H,1-4,9H2	ZUENLBQQNMTFPU-UHFFFAOYSA-N	315720	US10172859, Example 141::[2-Chloro-4-fluoro-5-(7-morpholin-4-ylpyrido[4,3-d}pyrimidin-4-yl)phenyl]-(4-hydroxymethylthiazol-2-yl)methanol ::US9732094, Example 141::US11065253, Example 141	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315720	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315720&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696307	383542449							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616410	OCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN4O3S/c24-18-9-19(25)17(8-16(18)22(31)23-28-13(10-30)11-33-23)21-15-2-1-14(7-20(15)26-12-27-21)29-3-5-32-6-4-29/h1-2,7-9,11-12,22,30-31H,3-6,10H2	FTJCWHDAYCNQKH-UHFFFAOYSA-N	315721	US10172859, Example 142::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- hydroxymethyl- thiazol-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.75-7.69 (m, 2H), 7.59-7.49 (m, 2H),7.36 (t, J = 1.1, 1H), 7.23-7.17 (m, 1H), 7.00(d, J = 5.1, 1H), 6.27 (d, J = 5.0, 1H), 5.24 (t,J = 5.7, 1H), 4.52-4.45 (m, 2H), 3.81-3.74 (m,4H), 3.49-3.41 (m, 4H)::US9732094, Example 142::US11065253, Example 142	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315721	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315721&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954746	383542450							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616412	CNCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23ClFN5O2S/c1-27-11-14-12-34-24(30-14)23(32)17-9-18(20(26)10-19(17)25)22-16-3-2-15(8-21(16)28-13-29-22)31-4-6-33-7-5-31/h2-3,8-10,12-13,23,27,32H,4-7,11H2,1H3	RAMIQEMCKWWMBT-UHFFFAOYSA-N	315722	US10172859, Example 143::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- methylaminomethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.26 (s, 1H), 7.76-7.69 (m, 2H), 7.58-7.50 (m, 2H), 7.48-7.43 (m, 1H), 7.24-7.16(m, 1H), 6.97 (s, 1H), 6.28 (s, 1H), 3.80 (s,2H), 3.79-3.74 (m, 4H), 3.48-3.42 (m, 4H),2.33 (s, 3H)::US9732094, Example 143::US11065253, Example 143	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315722	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315722&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696327	383542451							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616414	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C20H17FN4O2S2/c21-14-2-1-12(18(26)20-22-3-8-28-20)9-13(14)17-19-15(23-11-24-17)10-16(29-19)25-4-6-27-7-5-25/h1-3,8-11,18,26H,4-7H2	AIDFNPQAXSJWSH-UHFFFAOYSA-N	315723	[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]thiazol-2- yl-methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.76 (dd, J = 7.0, 2.3, 1H), 7.73 (d, J = 3.2,1H), 7.69-7.64 (m, 2H), 7.43-7.38 (m, 1H),6.96 (d, J = 4.6, 1H), 6.53 (s, 1H), 6.07 (d,J = 4.6, 1H), 3.77-3.71 (m, 4H), 3.44-3.38 (m,4H)::US10172859, Example 145::US10172859, Example 146::US10172859, Example 144::US9732094, Example 146::US11065253, Example 146	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315723	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315723&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696438	383542452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616416	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C20H17FN4O2S2/c21-14-2-1-12(18(26)20-22-3-8-28-20)9-13(14)17-19-15(23-11-24-17)10-16(29-19)25-4-6-27-7-5-25/h1-3,8-11,18,26H,4-7H2	AIDFNPQAXSJWSH-UHFFFAOYSA-N	315723	[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]thiazol-2- yl-methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.76 (dd, J = 7.0, 2.3, 1H), 7.73 (d, J = 3.2,1H), 7.69-7.64 (m, 2H), 7.43-7.38 (m, 1H),6.96 (d, J = 4.6, 1H), 6.53 (s, 1H), 6.07 (d,J = 4.6, 1H), 3.77-3.71 (m, 4H), 3.44-3.38 (m,4H)::US10172859, Example 145::US10172859, Example 146::US10172859, Example 144::US9732094, Example 146::US11065253, Example 146	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315723	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315723&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696438	383542452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616418	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C20H17FN4O2S2/c21-14-2-1-12(18(26)20-22-3-8-28-20)9-13(14)17-19-15(23-11-24-17)10-16(29-19)25-4-6-27-7-5-25/h1-3,8-11,18,26H,4-7H2	AIDFNPQAXSJWSH-UHFFFAOYSA-N	315723	[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]thiazol-2- yl-methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.76 (dd, J = 7.0, 2.3, 1H), 7.73 (d, J = 3.2,1H), 7.69-7.64 (m, 2H), 7.43-7.38 (m, 1H),6.96 (d, J = 4.6, 1H), 6.53 (s, 1H), 6.07 (d,J = 4.6, 1H), 3.77-3.71 (m, 4H), 3.44-3.38 (m,4H)::US10172859, Example 145::US10172859, Example 146::US10172859, Example 144::US9732094, Example 146::US11065253, Example 146	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315723	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315723&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696438	383542452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616420	OC(c1ccc(s1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccs1	InChI=1S/C20H18N4O2S2/c25-19(20-21-5-10-27-20)17-4-3-16(28-17)18-14-2-1-13(11-15(14)22-12-23-18)24-6-8-26-9-7-24/h1-5,10-12,19,25H,6-9H2	VURHFAWQGNOLNC-UHFFFAOYSA-N	315726	[5-(7-Morpholin-4- ylquinazolin-4-yl)- thiophen-2-yl]- thiazol-2-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 8.93 (s,1H), 8.34 (d, J = 9.5, 1H), 7.83 (d, J = 3.9, 1H),7.79 (d, J = 3.2, 1H), 7.71 (d, J = 3.2, 1H), 7.56(dd, J = 9.5, 2.7, 1H), 7.32 (d, J = 4.8, 1H), 7.26-7.24 (m, 1H), 7.16 (d, J = 2.6, 1H), 6.31-6.29(m, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H)::US10172859, Example 160::US10172859, Example 161::US10172859, Example 147::US9732094, Example 147::US11065253, Example 161	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315726	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315726&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954835	383542453							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616422	OC(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H20N4O2S/c27-21(22-23-6-11-29-22)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)24-14-25-20)26-7-9-28-10-8-26/h1-6,11-14,21,27H,7-10H2	ICUMGURWJXOHLQ-UHFFFAOYSA-N	315727	US10172859, Example 149::[3-(7-Morpholin-4- ylquinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.86 (d, J = 9.4, 1H), 7.83-7.81 (m, 1H),7.74 (d, J = 3.2, 1H), 7.68-7.64 (m, 3H), 7.59-7.55 (m, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.20(d, J = 2.6, 1H), 6.93 (d, J = 4.5, 1H), 6.10 (d,J = 4.0, 1H), 3.80-3.76 (m, 4H), 3.46-3.42 (m,4H)::US10172859, Example 150::US10172859, Example 148::US9732094, Example 150::US11065253, Example 150	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315727&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954926	383542454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616424	OC(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H20N4O2S/c27-21(22-23-6-11-29-22)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)24-14-25-20)26-7-9-28-10-8-26/h1-6,11-14,21,27H,7-10H2	ICUMGURWJXOHLQ-UHFFFAOYSA-N	315727	US10172859, Example 149::[3-(7-Morpholin-4- ylquinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.86 (d, J = 9.4, 1H), 7.83-7.81 (m, 1H),7.74 (d, J = 3.2, 1H), 7.68-7.64 (m, 3H), 7.59-7.55 (m, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.20(d, J = 2.6, 1H), 6.93 (d, J = 4.5, 1H), 6.10 (d,J = 4.0, 1H), 3.80-3.76 (m, 4H), 3.46-3.42 (m,4H)::US10172859, Example 150::US10172859, Example 148::US9732094, Example 150::US11065253, Example 150	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315727&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954926	383542454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616426	OC(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H20N4O2S/c27-21(22-23-6-11-29-22)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)24-14-25-20)26-7-9-28-10-8-26/h1-6,11-14,21,27H,7-10H2	ICUMGURWJXOHLQ-UHFFFAOYSA-N	315727	US10172859, Example 149::[3-(7-Morpholin-4- ylquinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.86 (d, J = 9.4, 1H), 7.83-7.81 (m, 1H),7.74 (d, J = 3.2, 1H), 7.68-7.64 (m, 3H), 7.59-7.55 (m, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.20(d, J = 2.6, 1H), 6.93 (d, J = 4.5, 1H), 6.10 (d,J = 4.0, 1H), 3.80-3.76 (m, 4H), 3.46-3.42 (m,4H)::US10172859, Example 150::US10172859, Example 148::US9732094, Example 150::US11065253, Example 150	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315727	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315727&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954926	383542454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616429	CC(O)(c1nccs1)c1cncc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H21N5O2S/c1-22(28,21-24-4-9-30-21)16-10-15(12-23-13-16)20-18-3-2-17(11-19(18)25-14-26-20)27-5-7-29-8-6-27/h2-4,9-14,28H,5-8H2,1H3	WZGXFUTUWYUZBK-UHFFFAOYSA-N	315717	1-[5-(7-Morpholin-4-ylquinazolin-4-yl)pyridin-3-yl]-1-thiazol-2-ylethanol (EXAMPLE 138)::US10172859, Example 151::US10172859, Example 152::US10172859, Example 138::US9732094, Example 152::US11065253, Example 152	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315717&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696290	383542446							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616432	CC(O)(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22N4O2S/c1-23(28,22-24-7-12-30-22)17-4-2-3-16(13-17)21-19-6-5-18(14-20(19)25-15-26-21)27-8-10-29-11-9-27/h2-7,12-15,28H,8-11H2,1H3	BFPJNIQERRPKOK-UHFFFAOYSA-N	315733	US10172859, Example 154::1-[3-(7-Morpholin- 4-ylquinazolin-4-yl)- phenyl]-1-thiazol-2- ylethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.96-7.93 (m, 1H), 7.83 (d, J = 9.4, 1H),7.79-7.76 (m, 1H), 7.74 (d, J = 3.2, 1H), 7.63-7.61 (m, 1H), 7.60 (d, J = 3.3, 1H), 7.55 (d,J = 7.7, 1H), 7.53-7.50 (m, 1H), 7.20 (d, J = 2.6,1H), 6.82 (s, 1H), 3.81-3.75 (m, 4H), 3.47-3.42 (m, 4H), 1.98 (s, 3H)::US9732094, Example 154::US11065253, Example 154	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315733	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315733&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711769	383542456							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616438	OC(c1nccs1)(c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1)C(F)(F)F	InChI=1S/C23H19F3N4O2S/c24-23(25,26)22(31,21-27-6-11-33-21)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)28-14-29-20)30-7-9-32-10-8-30/h1-6,11-14,31H,7-10H2	QOLLQIBBKMYYHN-UHFFFAOYSA-N	315738	2,2,2-Trifluoro-1-[3- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-thiazol-2- ylethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.54 (s, 1H), 8.15-8.13 (m, 1H), 7.98-7.95 (m, 1H), 7.94 (d, J = 3.3, 1H), 7.87 (d,J = 3.2, 1H), 7.83-7.79 (m, 2H), 7.67 (t, J = 7.8,1H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.21 (d, J = 2.6,1H), 3.80-3.76 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 172::US10172859, Example 173::US10172859, Example 159::US9732094, Example 173::US11065253, Example 173	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315738&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711794	383542459							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616443	CC(O)(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-23(29,22-25-6-11-31-22)15-2-5-19(24)18(12-15)21-17-4-3-16(13-20(17)26-14-27-21)28-7-9-30-10-8-28/h2-6,11-14,29H,7-10H2,1H3	WUOHIOVTQJRGGL-UHFFFAOYSA-N	315742	US10172859, Example 163::1-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-thiazol- 2-ylethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.82-7.75 (m, 2H), 7.73 (d, J = 3.2, 1H),7.61 (d, J = 3.2, 1H), 7.53-7.50 (m, 2H), 7.41-7.36 (m, 1H), 7.20 (d, J = 1.9, 1H), 6.90 (s, 1H),3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H), 1.95(s, 3H)::US9732094, Example 163::US11065253, Example 163	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315742	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315742&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711799	383542461							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616452	OC(c1nccs1)c1cc(F)c(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H18F2N4O2S/c23-17-10-13(21(29)22-25-3-8-31-22)9-16(19(17)24)20-15-2-1-14(11-18(15)26-12-27-20)28-4-6-30-7-5-28/h1-3,8-12,21,29H,4-7H2	YYXOQNNOPYQUJY-UHFFFAOYSA-N	315750	US10172859, Example 178::US10172859, Example 179::[3,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.75 (d, J = 3.2, 1H), 7.72-7.66 (m, 2H),7.61-7.57 (m, 1H), 7.56-7.49 (m, 2H), 7.21(d, J = 2.4, 1H), 7.10 (d, J = 4.8, 1H), 6.10 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m,4H)::US10172859, Example 171::US9732094, Example 179::US11065253, Example 179	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954936	383542465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616455	OC(c1nccs1)(c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1)C(F)(F)F	InChI=1S/C23H19F3N4O2S/c24-23(25,26)22(31,21-27-6-11-33-21)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)28-14-29-20)30-7-9-32-10-8-30/h1-6,11-14,31H,7-10H2	QOLLQIBBKMYYHN-UHFFFAOYSA-N	315738	2,2,2-Trifluoro-1-[3- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-thiazol-2- ylethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.54 (s, 1H), 8.15-8.13 (m, 1H), 7.98-7.95 (m, 1H), 7.94 (d, J = 3.3, 1H), 7.87 (d,J = 3.2, 1H), 7.83-7.79 (m, 2H), 7.67 (t, J = 7.8,1H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.21 (d, J = 2.6,1H), 3.80-3.76 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 172::US10172859, Example 173::US10172859, Example 159::US9732094, Example 173::US11065253, Example 173	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315738	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315738&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711794	383542459							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616460	COC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-29-22(23-25-6-11-31-23)15-2-5-19(24)18(12-15)21-17-4-3-16(13-20(17)26-14-27-21)28-7-9-30-10-8-28/h2-6,11-14,22H,7-10H2,1H3	KITWWWFLDQOYEC-UHFFFAOYSA-N	315754	US10172859, Example 176::US10172859, Example 177::4-[2-Fluoro-5- (methoxy-thiazol-2- ylmethyl)phenyl]-7- morpholin-4-yl- quinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.78 (d, J = 3.2, 1H), 7.73 (d, J = 3.2, 1H),7.67-7.62 (m, 2H), 7.54-7.52 (m, 2H), 7.49-7.44 (m, 1H), 7.21-7.19 (m, 1H), 5.84 (s, 1H),3.80-3.75 (m, 4H), 3.46-3.43 (m, 4H), 3.43(s, 3H)::US10172859, Example 175::US9732094, Example 177::US11065253, Example 177	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315754	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315754&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954858	383542467							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616462	OC(c1nccs1)c1cc(F)c(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H18F2N4O2S/c23-17-10-13(21(29)22-25-3-8-31-22)9-16(19(17)24)20-15-2-1-14(11-18(15)26-12-27-20)28-4-6-30-7-5-28/h1-3,8-12,21,29H,4-7H2	YYXOQNNOPYQUJY-UHFFFAOYSA-N	315750	US10172859, Example 178::US10172859, Example 179::[3,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.75 (d, J = 3.2, 1H), 7.72-7.66 (m, 2H),7.61-7.57 (m, 1H), 7.56-7.49 (m, 2H), 7.21(d, J = 2.4, 1H), 7.10 (d, J = 4.8, 1H), 6.10 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m,4H)::US10172859, Example 171::US9732094, Example 179::US11065253, Example 179	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954936	383542465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616464	OC(c1nccs1)c1cc(F)c(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H18F2N4O2S/c23-17-10-13(21(29)22-25-3-8-31-22)9-16(19(17)24)20-15-2-1-14(11-18(15)26-12-27-20)28-4-6-30-7-5-28/h1-3,8-12,21,29H,4-7H2	YYXOQNNOPYQUJY-UHFFFAOYSA-N	315750	US10172859, Example 178::US10172859, Example 179::[3,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.75 (d, J = 3.2, 1H), 7.72-7.66 (m, 2H),7.61-7.57 (m, 1H), 7.56-7.49 (m, 2H), 7.21(d, J = 2.4, 1H), 7.10 (d, J = 4.8, 1H), 6.10 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m,4H)::US10172859, Example 171::US9732094, Example 179::US11065253, Example 179	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315750	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954936	383542465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616466	OC(c1nccs1)c1cnc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-20-16(9-13(11-24-20)19(28)21-23-3-8-30-21)18-15-2-1-14(10-17(15)25-12-26-18)27-4-6-29-7-5-27/h1-3,8-12,19,28H,4-7H2	HORBNTVKYAVYTP-UHFFFAOYSA-N	315759	[6-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]thiazol- 2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56-8.52 (m, 1H), 8.21 (dd, J = 9.0, 2.3,1H), 7.77 (d, J = 3.2, 1H), 7.69 (d, J = 3.2, 1H),7.59-7.52 (m, 2H), 7.23-7.20 (m, 1H), 7.18(d, J = 4.7, 1H), 6.23 (d, J = 4.5, 1H), 3.82-3.73(m, 4H), 3.50-3.42 (m, 4H)::US10172859, Example 188::US10172859, Example 189::US10172859, Example 180::US9732094, Example 189::US11065253, Example 189	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954807	383542468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616468	Cc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN4O2S/c1-13-11-32-23(28-13)22(30)16-9-17(19(25)10-18(16)24)21-15-3-2-14(8-20(15)26-12-27-21)29-4-6-31-7-5-29/h2-3,8-12,22,30H,4-7H2,1H3	ZNMXTDAANBXETP-UHFFFAOYSA-N	315760	US10172859, Example 181::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4-methyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.73 (dd, J = 10.5, 8.6, 2H), 7.57-7.51 (m,2H), 7.22-7.18 (m, 2H), 6.97 (s, 1H), 6.26 (s,1H), 3.80-3.74 (m, 4H), 3.49-3.41 (m, 4H),2.30 (d, J = 1.0, 3H)::US9732094, Example 181::US11065253, Example 181	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315760	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315760&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954774	383542469							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616473	OCc1csc(n1)[C@@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C23H20ClFN4O3S/c24-18-9-19(25)17(8-16(18)22(31)23-28-13(10-30)11-33-23)21-15-2-1-14(7-20(15)26-12-27-21)29-3-5-32-6-4-29/h1-2,7-9,11-12,22,30-31H,3-6,10H2	FTJCWHDAYCNQKH-UHFFFAOYSA-N	315764	US10172859, Example 185::(S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- hydroxymethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.73 (dd, J = 8.6, 4.8, 2H), 7.58-7.50 (m,2H), 7.39-7.34 (m, 1H), 7.22-7.18 (m, 1H),7.02 (d, J = 5.0, 1H), 6.27 (d, J = 5.0, 1H), 5.27(t, J = 5.7, 1H), 4.51-4.47 (m, 2H), 3.80-3.74(m, 4H), 3.48-3.40 (m, 4H)::US9732094, Example 185::US11065253, Example 185	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315764	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315764&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954745	383542471							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616475	OCc1csc(n1)[C@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C23H20ClFN4O3S/c24-18-9-19(25)17(8-16(18)22(31)23-28-13(10-30)11-33-23)21-15-2-1-14(7-20(15)26-12-27-21)29-3-5-32-6-4-29/h1-2,7-9,11-12,22,30-31H,3-6,10H2	FTJCWHDAYCNQKH-UHFFFAOYSA-N	315765	US10172859, Example 186::(R)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- hydroxymethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.73 (dd, J = 8.6, 4.5, 2H), 7.57-7.52 (m,2H), 7.38-7.35 (m, 1H), 7.22-7.19 (m, 1H),7.03 (d, J = 5.0, 1H), 6.27 (d, J = 5.0, 1H), 5.27(t, J = 5.7, 1H), 4.50-4.46 (m, 2H), 3.80-3.74(m, 4H), 3.48-3.42 (m, 4H)::US9732094, Example 186::US11065253, Example 186	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315765	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315765&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954897	383542472							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616477	OCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1C2CCC1COC2	InChI=1S/C25H22ClFN4O3S/c26-20-7-21(27)19(6-18(20)24(33)25-30-13(8-32)11-35-25)23-17-4-3-14(5-22(17)28-12-29-23)31-15-1-2-16(31)10-34-9-15/h3-7,11-12,15-16,24,32-33H,1-2,8-10H2	VSYCUCYLHGGKPK-UHFFFAOYSA-N	315766	US10172859, Example 187::{2-Chloro-4-fluoro- 5-[7-(3-oxa-8-aza- bicyclo[3.2.1]oct-8- yl)quinazolin-4-yl]- phenyl}-(4-hydroxy- methylthiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.03 (s,1H), 7.71 (t, J = 8.5, 2H), 7.50 (dd, J = 9.3, 3.2,1H), 7.40 (dd, J = 9.4, 2.5, 1H), 7.37-7.35 (m,1H), 7.13 (d, J = 2.4, 1H), 7.01 (d, J = 5.1, 1H),6.27 (d, J = 5.0, 1H), 5.26 (t, J = 5.7, 1H), 4.52-4.50 (m, 2H), 4.50-4.47 (m, 2H), 3.69 (d,J = 10.9, 2H), 3.57-3.50 (m, 2H), 2.09-1.94(m, 4H)::US9732094, Example 187::US11065253, Example 187	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315766	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315766&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954749	383542473							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616479	OC(c1nccs1)c1cnc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-20-16(9-13(11-24-20)19(28)21-23-3-8-30-21)18-15-2-1-14(10-17(15)25-12-26-18)27-4-6-29-7-5-27/h1-3,8-12,19,28H,4-7H2	HORBNTVKYAVYTP-UHFFFAOYSA-N	315759	[6-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]thiazol- 2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56-8.52 (m, 1H), 8.21 (dd, J = 9.0, 2.3,1H), 7.77 (d, J = 3.2, 1H), 7.69 (d, J = 3.2, 1H),7.59-7.52 (m, 2H), 7.23-7.20 (m, 1H), 7.18(d, J = 4.7, 1H), 6.23 (d, J = 4.5, 1H), 3.82-3.73(m, 4H), 3.50-3.42 (m, 4H)::US10172859, Example 188::US10172859, Example 189::US10172859, Example 180::US9732094, Example 189::US11065253, Example 189	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954807	383542468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616481	OC(c1nccs1)c1cnc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-20-16(9-13(11-24-20)19(28)21-23-3-8-30-21)18-15-2-1-14(10-17(15)25-12-26-18)27-4-6-29-7-5-27/h1-3,8-12,19,28H,4-7H2	HORBNTVKYAVYTP-UHFFFAOYSA-N	315759	[6-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]thiazol- 2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56-8.52 (m, 1H), 8.21 (dd, J = 9.0, 2.3,1H), 7.77 (d, J = 3.2, 1H), 7.69 (d, J = 3.2, 1H),7.59-7.52 (m, 2H), 7.23-7.20 (m, 1H), 7.18(d, J = 4.7, 1H), 6.23 (d, J = 4.5, 1H), 3.82-3.73(m, 4H), 3.50-3.42 (m, 4H)::US10172859, Example 188::US10172859, Example 189::US10172859, Example 180::US9732094, Example 189::US11065253, Example 189	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315759	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954807	383542468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616483	CCNCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25ClFN5O2S/c1-2-28-12-15-13-35-25(31-15)24(33)18-10-19(21(27)11-20(18)26)23-17-4-3-16(9-22(17)29-14-30-23)32-5-7-34-8-6-32/h3-4,9-11,13-14,24,28,33H,2,5-8,12H2,1H3	QYNNKWUEYHNEOA-UHFFFAOYSA-N	315769	US10172859, Example 190::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4-ethyl- aminomethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.25 (s, 1H), 7.73 (d, J = 1.6, 1H), 7.71 (s,1H), 7.58-7.49 (m, 2H), 7.44-7.40 (m, 1H),7.23-7.18 (m, 1H), 7.05 (s, 1H), 6.27 (s, 1H),3.80-3.76 (m, 6H), 3.48-3.40 (m, 4H), 2.60(q, J = 7.1, 2H), 1.01 (t, J = 7.1, 3H)::US9732094, Example 190::US11065253, Example 190	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315769	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315769&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954972	383542474							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616485	CCNCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25ClFN5O2S/c1-2-28-12-15-13-35-25(31-15)24(33)18-10-19(21(27)11-20(18)26)23-17-4-3-16(9-22(17)29-14-30-23)32-5-7-34-8-6-32/h3-4,9-11,13-14,24,28,33H,2,5-8,12H2,1H3	QYNNKWUEYHNEOA-UHFFFAOYSA-N	315769	US10172859, Example 190::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4-ethyl- aminomethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.25 (s, 1H), 7.73 (d, J = 1.6, 1H), 7.71 (s,1H), 7.58-7.49 (m, 2H), 7.44-7.40 (m, 1H),7.23-7.18 (m, 1H), 7.05 (s, 1H), 6.27 (s, 1H),3.80-3.76 (m, 6H), 3.48-3.40 (m, 4H), 2.60(q, J = 7.1, 2H), 1.01 (t, J = 7.1, 3H)::US9732094, Example 190::US11065253, Example 190	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315769	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315769&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954972	383542474							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616487	Cn1cc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2/c1-28-13-16(12-27-28)23(30)15-2-5-20(24)19(10-15)22-18-4-3-17(11-21(18)25-14-26-22)29-6-8-31-9-7-29/h2-5,10-14,23,30H,6-9H2,1H3	DLENRIORLMKFNS-UHFFFAOYSA-N	315770	US10172859, Example 191::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazol-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.68-7.33 (m, 6H), 7.31-7.15 (m, 2H),5.76 (s, 2H), 3.90-3.64 (m, 7H), 3.51-3.39(m, 4H)::US9732094, Example 191::US11065253, Example 191	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315770	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954823	383542475							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616489	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)15-7-14(9-25-21(15)23)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	FWJBVJNPRGKVFD-UHFFFAOYSA-N	315771	US10172859, Example 192::(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.14 (s,1H), 9.09 (s, 1H), 8.67-8.65 (m, 1H), 8.46(dd, J = 9.0, 2.4, 1H), 7.03-6.99 (m, 2H), 6.11(d, J = 5.2, 1H), 3.77-3.68 (m, 8H), 2.31 (s,3H), 2.19 (s, 3H)::US9732094, Example 192::US11065253, Example 192	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315771	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315771&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955003	383542476							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616491	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2S/c1-13-14(2)32-23(28-13)21(30)18-9-15(11-25-22(18)24)20-17-4-3-16(10-19(17)26-12-27-20)29-5-7-31-8-6-29/h3-4,9-12,21,30H,5-8H2,1-2H3	JZLKXSPJLMDHOQ-UHFFFAOYSA-N	315772	US10172859, Example 205::US10172859, Example 206::(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.58-8.56 (m, 1H), 8.37 (dd, J = 9.0, 2.4,1H), 7.87 (d, J = 9.4, 1H), 7.57 (dd, J = 9.4, 2.6,1H), 7.22 (d, J = 2.5, 1H), 6.99 (d, J = 5.1, 1H),6.11 (d, J = 5.1, 1H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H), 2.30 (s, 3H), 2.19 (s, 3H)::US10172859, Example 194::US9732094, Example 206::US11065253, Example 206	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954971	383542477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616493	Cc1csc(n1)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C21H19FN6O2S/c1-12-10-31-21(27-12)19(29)13-6-14(20(22)24-8-13)18-15-9-23-17(7-16(15)25-11-26-18)28-2-4-30-5-3-28/h6-11,19,29H,2-5H2,1H3	NVCSVGUFUPGXIG-UHFFFAOYSA-N	315773	US10172859, Example 195::[6-Fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]-(4- methyl-thiazol-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.17 (s,1H), 8.90 (d, J = 2.5, 1H), 8.57-8.53 (m, 1H),8.29 (dd, J = 9.1, 2.4, 1H), 7.24-7.21 (m, 1H),7.10 (d, J = 4.9, 1H), 7.00 (s, 1H), 6.16 (d,J = 4.9, 1H), 3.79-3.67 (m, 8H), 2.33 (d, J = 1.0,3H)::US9732094, Example 195::US11065253, Example 195	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315773	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966380	383542478							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616495	Cc1nc(sc1C)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)14-7-15(21(23)25-9-14)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	CSNOKHOWFALBPK-UHFFFAOYSA-N	315774	(4,5-Dimethyl- thiazol-2-yl)-[6- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.90 (d, J = 2.4, 1H), 8.53 (d, J = 2.3, 1H),8.27 (dd, J = 9.1, 2.4, 1H), 7.06 (d, J = 4.9, 1H),6.99 (s, 1H), 6.08 (d, J = 4.9, 1H), 3.76-3.69(m, 8H), 2.30 (s, 3H), 2.21 (s, 3H)::US10172859, Example 203::US10172859, Example 204::US10172859, Example 196::US9732094, Example 204::US11065253, Example 204	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954852	383542479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616497	CC(C)n1cc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H26FN5O2/c1-16(2)31-14-18(13-29-31)25(32)17-3-6-22(26)21(11-17)24-20-5-4-19(12-23(20)27-15-28-24)30-7-9-33-10-8-30/h3-6,11-16,25,32H,7-10H2,1-2H3	RWAYQUVHYMUCJE-UHFFFAOYSA-N	315775	US10172859, Example 197::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1- isopropyl-1H- pyrazol-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.64-7.60 (m, 1H), 7.60-7.57 (m, 2H),7.56-7.50 (m, 2H), 7.41-7.35 (m, 1H), 7.28(s, 1H), 7.20 (d, J = 2.2, 1H), 5.76 (s, 2H), 4.42(h, J = 6.6, 1H), 3.80-3.76 (m, 4H), 3.46-3.42(m, 4H), 1.36 (d, J = 6.7, 6H)::US9732094, Example 197::US11065253, Example 197	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315775	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315775&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954976	383542480							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616499	CC(C)(C)n1cc(cn1)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H27FN6O2/c1-25(2,3)32-14-17(13-30-32)23(33)20-10-16(12-27-24(20)26)22-19-5-4-18(11-21(19)28-15-29-22)31-6-8-34-9-7-31/h4-5,10-15,23,33H,6-9H2,1-3H3	GJESUBAPEJHPIP-UHFFFAOYSA-N	315776	US10172859, Example 198::(1-tert-Butyl-1H- pyrazol-4-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.54-8.49 (m, 1H), 8.46 (dd, J = 9.4, 2.6,1H), 7.89 (d, J = 9.4, 1H), 7.73 (s, 1H), 7.57(dd, J = 9.5, 2.6, 1H), 7.36 (s, 1H), 7.23 (d,J = 2.5, 1H), 6.02 (d, J = 4.8, 1H), 5.95 (d, J =4.6, 1H), 3.82-3.75 (m, 4H), 3.50-3.42 (m, 4H),1.48 (s, 9H)::US9732094, Example 198::US11065253, Example 198	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315776	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315776&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954781	383542481							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616501	FC(F)OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19F3N4O2S/c24-18-4-1-14(21(32-23(25)26)22-27-5-10-33-22)11-17(18)20-16-3-2-15(12-19(16)28-13-29-20)30-6-8-31-9-7-30/h1-5,10-13,21,23H,6-9H2	OALIVDXCYALUSU-UHFFFAOYSA-N	315777	US10172859, Example 199::4-[5-(Difluoro- methoxy-thiazol-2- ylmethyl)-2-fluoro- phenyl]-7- morpholin-4-yl- quinazoline1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.85 (d, J = 3.2, 1H), 7.81 (d, J = 3.2, 1H),7.73-7.71 (m, 2H), 7.55-7.52 (m, 2H), 7.52-7.48 (m, 1H), 7.22-6.82 (m, 3H), 3.80-3.75(m, 4H), 3.48-3.42 (m, 4H)::US9732094, Example 199::US11065253, Example 199	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315777	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315777&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954812	383542482							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616503	Cc1nc(sc1CO)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23FN4O3S/c1-14-21(12-30)33-24(28-14)23(31)15-2-5-19(25)18(10-15)22-17-4-3-16(11-20(17)26-13-27-22)29-6-8-32-9-7-29/h2-5,10-11,13,23,30-31H,6-9,12H2,1H3	ZYEYIBTVJPAKBV-UHFFFAOYSA-N	315778	US10172859, Example 200::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-hydroxy- methyl-4-methyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.70-7.63 (m, 2H), 7.55-7.50 (m, 2H),7.44-7.39 (m, 1H), 7.22-7.19 (m, 1H), 6.81(d, J = 4.5, 1H), 5.95 (d, J = 4.3, 1H), 5.35 (t,J = 5.6, 1H), 4.54 (d, J = 5.4, 2H), 3.80-3.75 (m,4H), 3.47-3.42 (m, 4H), 2.22 (s, 3H)::US9732094, Example 200::US11065253, Example 200	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315778	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315778&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966381	383542483							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616505	CC(O)c1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClFN4O3S/c1-13(31)21-11-34-24(29-21)23(32)16-9-17(19(26)10-18(16)25)22-15-3-2-14(8-20(15)27-12-28-22)30-4-6-33-7-5-30/h2-3,8-13,23,31-32H,4-7H2,1H3	ASWGTDOVISOWCF-UHFFFAOYSA-N	315779	US10172859, Example 201::1-(2-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}thiazol-4-yl)- ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11-9.09 (m, 1H), 7.75-7.70 (m, 2H), 7.55-7.52(m, 2H), 7.34-7.32 (m, 1H), 7.21-7.19 (m,1H), 7.00-6.96 (m, 1H), 6.28-6.25 (m, 1H),5.26-5.18 (m, 1H), 4.77-4.70 (m, 1H), 3.79-3.75 (m, 4H), 3.47-3.43 (m, 4H), 1.36-1.30(m, 3H)::US9732094, Example 201::US11065253, Example 201	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315779	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315779&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954894	383542484							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616507	CCn1cc(cn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23ClFN5O2/c1-2-31-13-15(12-29-31)24(32)18-10-19(21(26)11-20(18)25)23-17-4-3-16(9-22(17)27-14-28-23)30-5-7-33-8-6-30/h3-4,9-14,24,32H,2,5-8H2,1H3	QQVCKAJSGSGZCZ-UHFFFAOYSA-N	315780	US10172859, Example 202::[2-Chloro-4-fluoro- 5-(7-morpholin-4- ylquinazolin-4-yl)- phenyl]-(1-ethyl- 1H-pyrazol-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91-7.88 (m, 1H), 7.64 (d, J = 9.6, 1H),7.59 (dd, J = 9.4, 3.2, 1H), 7.57-7.52 (m, 2H),7.29 (s, 1H), 7.22-7.20 (m, 1H), 5.98 (d,J = 4.8, 1H, 5.93 (d, J = 4.8, 1H), 4.08-4.02 (m,2H), 3.80-3.76 (m, 4H), 3.48-3.43 (m, 4H),1.34-1.28 (m, 3H)::US9732094, Example 202::US11065253, Example 202	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315780	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315780&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966382	383542485							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616509	Cc1nc(sc1C)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)14-7-15(21(23)25-9-14)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	CSNOKHOWFALBPK-UHFFFAOYSA-N	315774	(4,5-Dimethyl- thiazol-2-yl)-[6- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.90 (d, J = 2.4, 1H), 8.53 (d, J = 2.3, 1H),8.27 (dd, J = 9.1, 2.4, 1H), 7.06 (d, J = 4.9, 1H),6.99 (s, 1H), 6.08 (d, J = 4.9, 1H), 3.76-3.69(m, 8H), 2.30 (s, 3H), 2.21 (s, 3H)::US10172859, Example 203::US10172859, Example 204::US10172859, Example 196::US9732094, Example 204::US11065253, Example 204	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954852	383542479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616511	Cc1nc(sc1C)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)14-7-15(21(23)25-9-14)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	CSNOKHOWFALBPK-UHFFFAOYSA-N	315774	(4,5-Dimethyl- thiazol-2-yl)-[6- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.90 (d, J = 2.4, 1H), 8.53 (d, J = 2.3, 1H),8.27 (dd, J = 9.1, 2.4, 1H), 7.06 (d, J = 4.9, 1H),6.99 (s, 1H), 6.08 (d, J = 4.9, 1H), 3.76-3.69(m, 8H), 2.30 (s, 3H), 2.21 (s, 3H)::US10172859, Example 203::US10172859, Example 204::US10172859, Example 196::US9732094, Example 204::US11065253, Example 204	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315774	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954852	383542479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616513	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2S/c1-13-14(2)32-23(28-13)21(30)18-9-15(11-25-22(18)24)20-17-4-3-16(10-19(17)26-12-27-20)29-5-7-31-8-6-29/h3-4,9-12,21,30H,5-8H2,1-2H3	JZLKXSPJLMDHOQ-UHFFFAOYSA-N	315772	US10172859, Example 205::US10172859, Example 206::(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.58-8.56 (m, 1H), 8.37 (dd, J = 9.0, 2.4,1H), 7.87 (d, J = 9.4, 1H), 7.57 (dd, J = 9.4, 2.6,1H), 7.22 (d, J = 2.5, 1H), 6.99 (d, J = 5.1, 1H),6.11 (d, J = 5.1, 1H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H), 2.30 (s, 3H), 2.19 (s, 3H)::US10172859, Example 194::US9732094, Example 206::US11065253, Example 206	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954971	383542477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616515	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2S/c1-13-14(2)32-23(28-13)21(30)18-9-15(11-25-22(18)24)20-17-4-3-16(10-19(17)26-12-27-20)29-5-7-31-8-6-29/h3-4,9-12,21,30H,5-8H2,1-2H3	JZLKXSPJLMDHOQ-UHFFFAOYSA-N	315772	US10172859, Example 205::US10172859, Example 206::(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.58-8.56 (m, 1H), 8.37 (dd, J = 9.0, 2.4,1H), 7.87 (d, J = 9.4, 1H), 7.57 (dd, J = 9.4, 2.6,1H), 7.22 (d, J = 2.5, 1H), 6.99 (d, J = 5.1, 1H),6.11 (d, J = 5.1, 1H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H), 2.30 (s, 3H), 2.19 (s, 3H)::US10172859, Example 194::US9732094, Example 206::US11065253, Example 206	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315772	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954971	383542477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616517	Cc1cc(F)c(cc1C(O)c1nccs1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-14-10-19(24)18(12-17(14)22(29)23-25-4-9-31-23)21-16-3-2-15(11-20(16)26-13-27-21)28-5-7-30-8-6-28/h2-4,9-13,22,29H,5-8H2,1H3	BIYBXRUQFCDOHJ-UHFFFAOYSA-N	315785	US10172859, Example 210::[4-Fluoro-2-methyl-5-(7-morpholinylquinazolin-4-yl)phenyl]thiazol-2-ylmethanol (EXAMPLE 207)::US10172859, Example 209::US10172859, Example 207::US9732094, Example 210::US11065253, Example 210	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696365	383542486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616519	OC(c1nccs1)c1ccc(F)c(c1)-c1nc(nc2cc(ccc12)N1CCOCC1)C#C	InChI=1S/C24H19FN4O2S/c1-2-21-27-20-14-16(29-8-10-31-11-9-29)4-5-17(20)22(28-21)18-13-15(3-6-19(18)25)23(30)24-26-7-12-32-24/h1,3-7,12-14,23,30H,8-11H2	MEFSRUHZMYIWLE-UHFFFAOYSA-N	315786	US10172859, Example 215::US10172859, Example 216::[3-(2-Ethynyl-7-morpholinylquinazolin-4-yl)-4-fluorophenyl]thiazol-2-ylmethanol (EXAMPLE 208)::US10172859, Example 208::US9732094, Example 216::US11065253, Example 216	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696405	383542487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616521	Cc1cc(F)c(cc1C(O)c1nccs1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-14-10-19(24)18(12-17(14)22(29)23-25-4-9-31-23)21-16-3-2-15(11-20(16)26-13-27-21)28-5-7-30-8-6-28/h2-4,9-13,22,29H,5-8H2,1H3	BIYBXRUQFCDOHJ-UHFFFAOYSA-N	315785	US10172859, Example 210::[4-Fluoro-2-methyl-5-(7-morpholinylquinazolin-4-yl)phenyl]thiazol-2-ylmethanol (EXAMPLE 207)::US10172859, Example 209::US10172859, Example 207::US9732094, Example 210::US11065253, Example 210	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696365	383542486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616523	Cc1cc(F)c(cc1C(O)c1nccs1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-14-10-19(24)18(12-17(14)22(29)23-25-4-9-31-23)21-16-3-2-15(11-20(16)26-13-27-21)28-5-7-30-8-6-28/h2-4,9-13,22,29H,5-8H2,1H3	BIYBXRUQFCDOHJ-UHFFFAOYSA-N	315785	US10172859, Example 210::[4-Fluoro-2-methyl-5-(7-morpholinylquinazolin-4-yl)phenyl]thiazol-2-ylmethanol (EXAMPLE 207)::US10172859, Example 209::US10172859, Example 207::US9732094, Example 210::US11065253, Example 210	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315785	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696365	383542486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616525	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H19FN4O2S/c23-18-4-1-14(21(28)22-24-5-10-30-22)11-17(18)20-16-3-2-15(12-19(16)25-13-26-20)27-6-8-29-9-7-27/h1-5,10-13,21,28H,6-9H2	XHIWYXBOVDWOHO-UHFFFAOYSA-N	315789	US10172859, Example 212::US10172859, Example 213::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2- ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.78-7.61 (m, 4H), 7.57-7.49 (m, 2H),7.46-7.37 (m, 1H), 7.23-7.17 (m, 1H), 6.95(s, 1H), 6.08 (s, 1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 211::US9732094, Example 213::US11065253, Example 213	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954919	383542488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616527	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H19FN4O2S/c23-18-4-1-14(21(28)22-24-5-10-30-22)11-17(18)20-16-3-2-15(12-19(16)25-13-26-20)27-6-8-29-9-7-27/h1-5,10-13,21,28H,6-9H2	XHIWYXBOVDWOHO-UHFFFAOYSA-N	315789	US10172859, Example 212::US10172859, Example 213::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2- ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.78-7.61 (m, 4H), 7.57-7.49 (m, 2H),7.46-7.37 (m, 1H), 7.23-7.17 (m, 1H), 6.95(s, 1H), 6.08 (s, 1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 211::US9732094, Example 213::US11065253, Example 213	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954919	383542488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616529	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H19FN4O2S/c23-18-4-1-14(21(28)22-24-5-10-30-22)11-17(18)20-16-3-2-15(12-19(16)25-13-26-20)27-6-8-29-9-7-27/h1-5,10-13,21,28H,6-9H2	XHIWYXBOVDWOHO-UHFFFAOYSA-N	315789	US10172859, Example 212::US10172859, Example 213::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2- ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.78-7.61 (m, 4H), 7.57-7.49 (m, 2H),7.46-7.37 (m, 1H), 7.23-7.17 (m, 1H), 6.95(s, 1H), 6.08 (s, 1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 211::US9732094, Example 213::US11065253, Example 213	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315789	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954919	383542488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616531	Cn1nccc1C(O)c1ccc(F)c(c1)-c1nc(Cl)nc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21ClFN5O2/c1-29-20(6-7-26-29)22(31)14-2-5-18(25)17(12-14)21-16-4-3-15(30-8-10-32-11-9-30)13-19(16)27-23(24)28-21/h2-7,12-13,22,31H,8-11H2,1H3	UIFRCTVMHZZAIO-UHFFFAOYSA-N	315792	US10172859, Example 214::[3-(2-Chloro-7- morpholin-4-yl- quinazolin-4-yl)- 4-fluoro-phenyl]- (2-methyl-2H- pyrazol-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 7.71-7.59 (m, 3H), 7.58-7.51 (m, 2H), 7.50-7.41(m, 1H), 7.31-7.26 (m, 1H), 7.18-7.12 (m,1H), 5.99 (s, 1H), 5.95-5.90 (m, 1H), 3.78 (s,3H), 3.78-3.73 (m, 4H), 3.52-3.45 (m, 4H)::US11065253, Example 214	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315792&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954992	383542489							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616533	OC(c1nccs1)c1ccc(F)c(c1)-c1nc(nc2cc(ccc12)N1CCOCC1)C#C	InChI=1S/C24H19FN4O2S/c1-2-21-27-20-14-16(29-8-10-31-11-9-29)4-5-17(20)22(28-21)18-13-15(3-6-19(18)25)23(30)24-26-7-12-32-24/h1,3-7,12-14,23,30H,8-11H2	MEFSRUHZMYIWLE-UHFFFAOYSA-N	315786	US10172859, Example 215::US10172859, Example 216::[3-(2-Ethynyl-7-morpholinylquinazolin-4-yl)-4-fluorophenyl]thiazol-2-ylmethanol (EXAMPLE 208)::US10172859, Example 208::US9732094, Example 216::US11065253, Example 216	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696405	383542487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616535	OC(c1nccs1)c1ccc(F)c(c1)-c1nc(nc2cc(ccc12)N1CCOCC1)C#C	InChI=1S/C24H19FN4O2S/c1-2-21-27-20-14-16(29-8-10-31-11-9-29)4-5-17(20)22(28-21)18-13-15(3-6-19(18)25)23(30)24-26-7-12-32-24/h1,3-7,12-14,23,30H,8-11H2	MEFSRUHZMYIWLE-UHFFFAOYSA-N	315786	US10172859, Example 215::US10172859, Example 216::[3-(2-Ethynyl-7-morpholinylquinazolin-4-yl)-4-fluorophenyl]thiazol-2-ylmethanol (EXAMPLE 208)::US10172859, Example 208::US9732094, Example 216::US11065253, Example 216	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315786	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696405	383542487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616537	OC(c1cccnc1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20F2N4O2/c25-20-12-21(26)19(24(31)15-2-1-5-27-13-15)11-18(20)23-17-4-3-16(10-22(17)28-14-29-23)30-6-8-32-9-7-30/h1-5,10-14,24,31H,6-9H2	YHVNTTRZSKTBOF-UHFFFAOYSA-N	315795	US10172859, Example 217::[2,4-Difluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]pyridin-3-ylmethanol ::US9732094, Example 217::US11065253, Example 217	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315795&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954959	383542490							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616539	OC(c1ccccn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20F2N4O2/c25-19-13-20(26)18(24(31)21-3-1-2-6-27-21)12-17(19)23-16-5-4-15(11-22(16)28-14-29-23)30-7-9-32-10-8-30/h1-6,11-14,24,31H,7-10H2	JMUJEVQDCVELNK-UHFFFAOYSA-N	315796	US10172859, Example 218::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridin-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.50-8.46 (m, 1H), 7.82 (td, J = 7.7, 1.8,1H), 7.68 (t, J = 8.1, 1H), 7.64-7.59 (m, 1H),7.57-7.50 (m, 2H), 7.43 (t, J = 10.1, 1H), 7.29-7.24 (m, 1H), 7.21-7.17 (m, 1H), 6.34 (d,J = 5.0, 1H), 6.02 (d, J = 5.0, 1H), 3.82-3.72 (m,4H), 3.48-3.41 (m, 4H).::US9732094, Example 218::US11065253, Example 218	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315796&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954763	383542491							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616541	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-30-22(32)5-4-20(29-30)24(33)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	NYVZJLKLJBXDKC-UHFFFAOYSA-N	315797	US10172859, Example 219::6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.85 (t, J = 8.1, 1H), 7.61-7.51 (m, 3H),7.47 (t, J = 10.1, 1H), 7.21 (d, J = 2.3, 1H), 6.94(d, J = 9.6, 1H), 6.56 (d, J = 4.8, 1H), 5.85 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.60 (s, 3H),3.48-3.42 (m, 4H)::US9732094, Example 219::US11065253, Example 219	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315797&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954888	383542492							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616543	Cn1nc(ccc1=O)C(O)c1ccc(F)c(c1F)-c1ncnc2cc(ccc12)N1CCOCC1 |(-2.67,-.39,;-2.67,1.15,;-1.33,1.93,;-1.33,3.47,;-2.67,4.23,;-4,3.47,;-4,1.93,;-5.33,1.16,;,4.23,;,5.78,;1.33,3.47,;2.67,4.23,;4,3.47,;4,1.93,;5.33,1.15,;2.67,1.15,;1.33,1.93,;,1.15,;2.67,-.38,;4,-1.15,;4,-2.69,;2.67,-3.47,;1.33,-2.69,;,-3.47,;-1.33,-2.69,;-1.33,-1.15,;,-.38,;1.33,-1.15,;-2.67,-3.47,;-4,-2.69,;-5.33,-3.47,;-5.33,-5,;-4,-5.78,;-2.67,-5,)|	InChI=1S/C24H21F2N5O3/c1-30-20(32)7-6-18(29-30)24(33)16-4-5-17(25)21(22(16)26)23-15-3-2-14(12-19(15)27-13-28-23)31-8-10-34-11-9-31/h2-7,12-13,24,33H,8-11H2,1H3	SGELBDISKAUAEL-UHFFFAOYSA-N	315798	US10172859, Example 220::6-{[2,4-Difluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.75 (d, J = 9.6, 1H), 7.67-7.61 (m, 1H),7.51 (qd, J = 9.4, 2.6, 2H), 7.32 (t, J = 8.8, 1H),7.20 (d, J = 2.3, 1H), 6.99 (d, J = 9.7, 1H), 6.64(d, J = 5.1, 1H), 6.02 (d, J = 5.1, 1H), 3.78 (t,J = 4.9, 4H), 3.57 (s, 3H), 3.45 (t, J = 4.9, 4H)::US9732094, Example 220::US11065253, Example 220	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315798&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954906	383542493							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616545	COc1ccc(cn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-33-23-5-2-15(13-28-23)25(32)19-11-18(20(26)12-21(19)27)24-17-4-3-16(10-22(17)29-14-30-24)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	CCKHVCHOSUZMRH-UHFFFAOYSA-N	315799	US10172859, Example 221::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridin-3-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.17 (d, J = 2.4, 1H), 7.84 (t, J = 8.2, 1H),7.63 (dd, J = 8.6, 2.5, 1H), 7.60-7.52 (m, 2H),7.44 (t, J = 10.2, 1H), 7.21 (d, J = 2.3, 1H), 6.79(d, J = 8.6, 1H), 6.22 (d, J = 4.0, 1H), 5.99 (d,J = 3.7, 1H), 3.83 (s, 3H), 3.80-3.76 (m, 4H),3.47-3.43 (m, 4H)::US9732094, Example 221::US11065253, Example 221	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315799&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954840	383542494							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616547	OC(c1ccc2ncnn2c1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-20-11-21(27)19(25(34)15-1-4-23-29-14-31-33(23)12-15)10-18(20)24-17-3-2-16(9-22(17)28-13-30-24)32-5-7-35-8-6-32/h1-4,9-14,25,34H,5-8H2	QAEAQPVUUPLITF-UHFFFAOYSA-N	315800	US10172859, Example 222::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[1,5-a]pyridin- 6-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.98-8.95 (m, 1H), 8.49 (s, 1H), 7.88 (t,J = 8.1, 1H), 7.83-7.80 (m, 1H), 7.62-7.56 (m,2H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.48 (t, J = 10.1,1H), 7.20 (d, J = 2.4, 1H), 6.52 (s, 1H), 6.17 (s,1H), 3.82-3.74 (m, 4H), 3.49-3.41 (m, 4H)::US9732094, Example 222::US11065253, Example 222	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315800&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955014	383542495							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616549	OC(c1cn2ccnc2cn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-11-20(27)18(25(34)22-13-33-4-3-28-23(33)12-29-22)10-17(19)24-16-2-1-15(9-21(16)30-14-31-24)32-5-7-35-8-6-32/h1-4,9-14,25,34H,5-8H2	FRGZDZJCSYUKHF-UHFFFAOYSA-N	315801	US10172859, Example 223::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-6-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s,1H), 9.06-9.02 (m, 1H), 8.83 (t, J = 1.3, 1H),8.25-8.22 (m, 1H), 7.86 (d, J = 1.0, 1H), 7.76 (t,J = 8.1, 1H), 7.63-7.56 (m, 2H), 7.52 (t, J = 10.1,1H), 7.24 (d, J = 2.1, 1H), 6.53 (d, J = 4.7, 1H),6.16 (d, J = 4.5, 1H), 3.87-3.80 (m, 4H), 3.54-3.46 (m, 4H)::US9732094, Example 223::US11065253, Example 223	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315801&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954896	383542496							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616551	COc1ccc(nc1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-33-16-3-5-22(28-13-16)25(32)19-11-18(20(26)12-21(19)27)24-17-4-2-15(10-23(17)29-14-30-24)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	QEZRHTYDAFPTCM-UHFFFAOYSA-N	315802	US10172859, Example 224::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyridin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.20-8.17 (m, 1H), 7.68 (t, J = 8.1, 1H),7.55-7.51 (m, 3H), 7.43-7.37 (m, 2H), 7.21-7.18 (m, 1H), 6.23 (d, J = 4.9, 1H), 5.98 (d,J = 4.6, 1H), 3.80 (s, 3H), 3.80-3.74 (m, 4H),::US9732094, Example 224::US11065253, Example 224	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315802&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954775	383542497							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616553	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 244::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 262::US10172859, Example 129::US9732094, Example 262::US11065253, Example 262	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616555	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 243::US10172859, Example 226::US10172859, Example 259::US10172859, Example 238::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)::US10172859, Example 78::US9732094, Example 259::US11065253, Example 259	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616557	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-20-3-2-18(29-30-20)23(32)14-9-15(17(25)10-16(14)24)21-22-19(27-12-28-21)8-13(11-26-22)31-4-6-34-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	NGZQOMGGFCGYBY-UHFFFAOYSA-N	315805	US10172859, Example 257::US10172859, Example 228::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate::US10172859, Example 227::US9732094, Example 257::US11065253, Example 257	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966394	383542498							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616559	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-20-3-2-18(29-30-20)23(32)14-9-15(17(25)10-16(14)24)21-22-19(27-12-28-21)8-13(11-26-22)31-4-6-34-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	NGZQOMGGFCGYBY-UHFFFAOYSA-N	315805	US10172859, Example 257::US10172859, Example 228::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate::US10172859, Example 227::US9732094, Example 257::US11065253, Example 257	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966394	383542498							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616561	CNC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC	InChI=1S/C26H24ClFN6O3/c1-29-25(35)22(24-26(36-2)31-6-5-30-24)17-12-18(20(28)13-19(17)27)23-16-4-3-15(11-21(16)32-14-33-23)34-7-9-37-10-8-34/h3-6,11-14,22H,7-10H2,1-2H3,(H,29,35)	NOVGLOQBGGWKSC-UHFFFAOYSA-N	315807	US10172859, Example 229::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxypyrazin-2- yl)-N-methyl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.26 (q, J = 4.5, 1H), 8.13 (d, J = 2.8, 1H), 8.11(d, J = 2.8, 1H), 7.73 (d, J = 9.6, 1H), 7.59 (dd,J = 9.4, 2.6, 1H), 7.56 (dd, J = 9.5, 2.3, 1H), 7.47 (d,J = 7.7, 1H), 7.20 (d, J = 2.2, 1H), 5.66 (s, 1H), 3.94(s, 3H), 3.80-3.71 (m, 4H), 3.48-3.42 (m, 4H),2.61 (d, J = 4.6, 3H).::US9732094, Example 229::US11065253, Example 229	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954808	383542499							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616563	CNC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C26H23ClFN5O2/c1-29-26(34)23(25-20(27)3-2-8-30-25)16-4-7-21(28)19(13-16)24-18-6-5-17(14-22(18)31-15-32-24)33-9-11-35-12-10-33/h2-8,13-15,23H,9-12H2,1H3,(H,29,34)	UUVNBMVWHDQRNZ-UHFFFAOYSA-N	315808	US10172859, Example 230::2-(3-Chloro-pyridin- 2-yl)-2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-N-methyl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.51 (dd, J = 4.7, 1.4, 1H), 8.03 (q, J = 4.4, 1H),7.92 (dd, J = 8.1, 1.5, 1H), 7.63 (dd, J = 9.4, 2.7, 1H),7.58-7.54 (m, 3H), 7.41-7.33 (m, 2H), 7.20 (d,J = 2.4, 1H), 5.52 (s, 1H), 3.85-3.71 (m, 4H), 3.51-3.40 (m, 4H), 2.60 (d, J = 4.6, 3H).::US9732094, Example 230	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315808&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711721	383542500							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616565	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-23-21(26-2-3-27-23)22(32)14-9-15(17(25)10-16(14)24)19-20-18(29-12-30-19)8-13(11-28-20)31-4-6-34-7-5-31/h2-3,8-12,22,32H,4-7H2,1H3	RRCYTFPMQJMLJV-UHFFFAOYSA-N	315809	US10172859, Example 232::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 247::US10172859, Example 231::US9732094, Example 247::US11065253, Example 247	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966396	383542501							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616567	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-23-21(26-2-3-27-23)22(32)14-9-15(17(25)10-16(14)24)19-20-18(29-12-30-19)8-13(11-28-20)31-4-6-34-7-5-31/h2-3,8-12,22,32H,4-7H2,1H3	RRCYTFPMQJMLJV-UHFFFAOYSA-N	315809	US10172859, Example 232::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 247::US10172859, Example 231::US9732094, Example 247::US11065253, Example 247	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966396	383542501							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616569	Cc1nccnc1[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cnc12)N1CCOCC1 |r|	InChI=1S/C23H21FN6O2/c1-14-20(26-5-4-25-14)23(31)15-2-3-18(24)17(10-15)21-22-19(28-13-29-21)11-16(12-27-22)30-6-8-32-9-7-30/h2-5,10-13,23,31H,6-9H2,1H3	JJEXYMGNEIIEPL-UHFFFAOYSA-N	315811	US10172859, Example 233::(S)-[4-Fluoro-3-(7- morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US9732094, Example 233::US11065253, Example 233	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315811&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954898	383542502							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616571	Cc1nccnc1[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cnc12)N1CCOCC1 |r|	InChI=1S/C23H21FN6O2/c1-14-20(26-5-4-25-14)23(31)15-2-3-18(24)17(10-15)21-22-19(28-13-29-21)11-16(12-27-22)30-6-8-32-9-7-30/h2-5,10-13,23,31H,6-9H2,1H3	JJEXYMGNEIIEPL-UHFFFAOYSA-N	315812	US10172859, Example 234::(R)-[4-Fluoro-3-(7- morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US9732094, Example 234::US11065253, Example 234	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315812&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696208	383542503							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616573	Fc1cc(Cl)c(Cc2ccc3nccn3n2)cc1-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O/c26-21-14-22(27)20(12-16(21)11-17-1-4-24-28-5-6-33(24)31-17)25-19-3-2-18(13-23(19)29-15-30-25)32-7-9-34-10-8-32/h1-6,12-15H,7-11H2	INTDVNQLZOTAHT-UHFFFAOYSA-N	315813	US10172859, Example 235::4-(4-Chloro-2-fluoro- 5-imidazo[1,2-b]- pyridazin-6-ylmethyl- phenyl)-7-morpholin- 4-ylquinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.22 (s, 1H), 8.07 (d, J = 9.4, 1H), 7.78-7.74(m, 2H), 7.74-7.71 (m, 1H), 7.60 (dd, J = 9.4, 3.1,1H), 7.54 (dd, J = 9.4, 2.5, 1H), 7.20 (d, J = 2.5, 1H),7.16 (d, J = 9.4, 1H), 4.42 (s, 2H), 3.80-3.75 (m,4H), 3.47-3.43 (m, 4H).::US9732094, Example 235::US11065253, Example 235	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315813&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696240	383542504							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616575	CNC(=O)C(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H23ClFN7O2/c1-30-27(37)25(22-4-5-24-31-6-7-36(24)34-22)18-13-19(21(29)14-20(18)28)26-17-3-2-16(12-23(17)32-15-33-26)35-8-10-38-11-9-35/h2-7,12-15,25H,8-11H2,1H3,(H,30,37)	XLTXMRIUYGBHCH-UHFFFAOYSA-N	315814	US10172859, Example 236::2-[2-Chloro-4-fluoro- 4-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-imidazo- [1,2-b]pyridazin-6-yl- N-methylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56 (q, J = 4.5, 1H), 8.26 (s, 1H), 8.10 (d,J = 9.5, 1H), 7.81 (d, J = 9.5, 1H), 7.77 (d, J = 1.2,1H), 7.74 (d, J = 7.6, 1H), 7.60 (dd, J = 9.4, 3.0, 1H),7.55 (dd, J = 9.4, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 7.12(d, J = 9.5, 1H), 5.62 (s, 1H), 3.81-3.75 (m, 4H),3.48-3.40 (m, 4H), 2.65 (d, J = 4.6, 3H).::US9732094, Example 236::US11065253, Example 236	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315814&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954752	383542505							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616577	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H21FN6O2/c1-14-20(26-5-4-25-14)23(31)15-2-3-18(24)17(10-15)21-22-19(28-13-29-21)11-16(12-27-22)30-6-8-32-9-7-30/h2-5,10-13,23,31H,6-9H2,1H3	JJEXYMGNEIIEPL-UHFFFAOYSA-N	315815	US10172859, Example 237::[4-Fluoro-3-(7-morpholin-4-ylpyrido[3,2-d}pyrimidin-4-yl)phenyl]-(3-methylpyrazin-2-yl)-methanol ::US9732094, Example 237::US11065253, Example 237	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315815&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696211	383542506							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616579	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 243::US10172859, Example 226::US10172859, Example 259::US10172859, Example 238::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)::US10172859, Example 78::US9732094, Example 259::US11065253, Example 259	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616581	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 244::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 262::US10172859, Example 129::US9732094, Example 262::US11065253, Example 262	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616583	Cc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O2/c1-13-20(27-3-2-26-13)23(32)15-9-16(18(25)10-17(15)24)21-22-19(29-12-30-21)8-14(11-28-22)31-4-6-33-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	BAUZLLBZQGLKDX-UHFFFAOYSA-N	315819	US10172859, Example 240::[2-Chloro-4-fluoro-5- (7-morphlin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.23 (s,1H), 9.06 (d, J = 2.9, 1H), 8.43 (d, J = 2.5, 1H), 8.33(d, J = 2.5, 1H), 8.05 (d, J = 7.5, 1H), 7.54 (d, J = 9.2,1H), 7.48 (d, J = 2.9, 1H), 6.65-6.27 (m, 1H), 6.25-6.22 (m, 1H), 3.82-3.77 (m, 4H), 3.58-3.52 (m,4H), 2.74 (s, 3H).::US9732094, Example 240::US11065253, Example 240	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315819&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966397	383542508							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616585	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 242::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 258::US10172859, Example 468::US10172859, Example 241::US9732094, Example 258::US11065253, Example 258	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616587	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 242::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 258::US10172859, Example 468::US10172859, Example 241::US9732094, Example 258::US11065253, Example 258	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616589	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 243::US10172859, Example 226::US10172859, Example 259::US10172859, Example 238::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)::US10172859, Example 78::US9732094, Example 259::US11065253, Example 259	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616591	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 244::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 262::US10172859, Example 129::US9732094, Example 262::US11065253, Example 262	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616593	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H20FN5O2S/c1-13-19(25-5-4-24-13)21(29)14-2-3-16(23)15(10-14)20-22-17(26-12-27-20)11-18(31-22)28-6-8-30-9-7-28/h2-5,10-12,21,29H,6-9H2,1H3	JVZGLRHIUDPKQN-UHFFFAOYSA-N	315824	[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 1)see racemate::US10172859, Example 265::US10172859, Example 246::US10172859, Example 245::US9732094, Example 265::US11065253, Example 265	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696361	383542510							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616595	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H20FN5O2S/c1-13-19(25-5-4-24-13)21(29)14-2-3-16(23)15(10-14)20-22-17(26-12-27-20)11-18(31-22)28-6-8-30-9-7-28/h2-5,10-12,21,29H,6-9H2,1H3	JVZGLRHIUDPKQN-UHFFFAOYSA-N	315824	[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 1)see racemate::US10172859, Example 265::US10172859, Example 246::US10172859, Example 245::US9732094, Example 265::US11065253, Example 265	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696361	383542510							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616597	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-23-21(26-2-3-27-23)22(32)14-9-15(17(25)10-16(14)24)19-20-18(29-12-30-19)8-13(11-28-20)31-4-6-34-7-5-31/h2-3,8-12,22,32H,4-7H2,1H3	RRCYTFPMQJMLJV-UHFFFAOYSA-N	315809	US10172859, Example 232::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 247::US10172859, Example 231::US9732094, Example 247::US11065253, Example 247	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966396	383542501							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616599	Cc1nccnc1[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1 |r|	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)17(10-15)23-21-19(26)11-16(12-20(21)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	GCFJFHHQAJXDCA-UHFFFAOYSA-N	315827	US10172859, Example 248::(R)-[4-Fluoro-3-(5- fluoro-7-morpholin-4- ylquinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US9732094, Example 248::US11065253, Example 248	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315827&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696390	383542511							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616601	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-24-22(28-2-3-29-24)23(33)14-10-15(17(26)11-16(14)25)21-20-18(27)8-13(9-19(20)30-12-31-21)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	OWOGJPGABWHWIU-UHFFFAOYSA-N	315828	US10172859, Example 266::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 250::US10172859, Example 249::US9732094, Example 266::US11065253, Example 266	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696440	383542512							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616603	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-24-22(28-2-3-29-24)23(33)14-10-15(17(26)11-16(14)25)21-20-18(27)8-13(9-19(20)30-12-31-21)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	OWOGJPGABWHWIU-UHFFFAOYSA-N	315828	US10172859, Example 266::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 250::US10172859, Example 249::US9732094, Example 266::US11065253, Example 266	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696440	383542512							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616605	Cc1nccnc1[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1 |r|	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)17(10-15)23-21-19(26)11-16(12-20(21)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	GCFJFHHQAJXDCA-UHFFFAOYSA-N	315830	US10172859, Example 251::(S)-[4-fluoro-3-(5- fluoro-7-morpholin-4- ylquinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US9732094, Example 251::US11065253, Example 251	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315830&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711725	383542513							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616607	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)14-2-3-17(25)16(10-14)21-20-18(26)11-15(12-19(20)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MBESFUDQRFVLFJ-UHFFFAOYSA-N	315831	US10172859, Example 253::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 267::US10172859, Example 252::US9732094, Example 267::US11065253, Example 267	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696418	383542514							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616609	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)14-2-3-17(25)16(10-14)21-20-18(26)11-15(12-19(20)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MBESFUDQRFVLFJ-UHFFFAOYSA-N	315831	US10172859, Example 253::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 267::US10172859, Example 252::US9732094, Example 267::US11065253, Example 267	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696418	383542514							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616611	CNC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C	InChI=1S/C26H24ClFN6O2/c1-15-24(31-6-5-30-15)23(26(35)29-2)18-12-19(21(28)13-20(18)27)25-17-4-3-16(11-22(17)32-14-33-25)34-7-9-36-10-8-34/h3-6,11-14,23H,7-10H2,1-2H3,(H,29,35)	ODLHJEBFKWXYOW-UHFFFAOYSA-N	315833	US10172859, Example 254::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-N-methyl-2- (3-methyl-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.41 (d, J = 2.6, 1H), 8.39 (d, J = 2.5, 1H), 8.30(q, J = 4.5, 1H), 7.74 (d, J = 9.5, 1H), 7.59 (dd,J = 9.4, 2.6, 1H), 7.55 (dd, J = 9.5, 2.4, 1H), 7.47 (d,J = 7.7, 1H), 7.20 (d, J = 2.3, 1H), 5.66 (s, 1H), 3.78(t, J = 5.8, 3.9, 4H), 3.46 (t, J = 4.9, 4H), 2.63 (d,J = 4.5, 3H), 2.52 (s, 3H).::US9732094, Example 254::US11065253, Example 254	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315833&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954895	383542515							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616613	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-5-4-19(29-30-21)24(32)14-2-3-17(25)16(10-14)23-22-18(26)11-15(12-20(22)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	OWXPXVCRAHRBLK-UHFFFAOYSA-N	315834	US10172859, Example 256::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 260::US10172859, Example 255::US9732094, Example 260::US11065253, Example 260	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696697	383542516							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616615	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-5-4-19(29-30-21)24(32)14-2-3-17(25)16(10-14)23-22-18(26)11-15(12-20(22)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	OWXPXVCRAHRBLK-UHFFFAOYSA-N	315834	US10172859, Example 256::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 260::US10172859, Example 255::US9732094, Example 260::US11065253, Example 260	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696697	383542516							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616617	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-20-3-2-18(29-30-20)23(32)14-9-15(17(25)10-16(14)24)21-22-19(27-12-28-21)8-13(11-26-22)31-4-6-34-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	NGZQOMGGFCGYBY-UHFFFAOYSA-N	315805	US10172859, Example 257::US10172859, Example 228::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate::US10172859, Example 227::US9732094, Example 257::US11065253, Example 257	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966394	383542498							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616619	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 242::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 258::US10172859, Example 468::US10172859, Example 241::US9732094, Example 258::US11065253, Example 258	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616621	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 243::US10172859, Example 226::US10172859, Example 259::US10172859, Example 238::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)::US10172859, Example 78::US9732094, Example 259::US11065253, Example 259	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616623	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-5-4-19(29-30-21)24(32)14-2-3-17(25)16(10-14)23-22-18(26)11-15(12-20(22)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	OWXPXVCRAHRBLK-UHFFFAOYSA-N	315834	US10172859, Example 256::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 260::US10172859, Example 255::US9732094, Example 260::US11065253, Example 260	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696697	383542516							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616625	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C25H21ClF2N6O3/c1-36-25-23(30-2-3-31-25)20(24(29)35)14-10-15(17(27)11-16(14)26)22-21-18(28)8-13(9-19(21)32-12-33-22)34-4-6-37-7-5-34/h2-3,8-12,20H,4-7H2,1H3,(H2,29,35)	ASBYXEDKVZWWLT-UHFFFAOYSA-N	315840	US10172859, Example 261::2-[2-Chloro-4-fluoro- 5-(5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (400 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.10 (d, J = 2.8, 1H), 8.07 (d, J = 2.8, 1H), 7.56(d, J = 7.7, 1H), 7.51 (d, J = 9.7, 1H), 7.41-6.85 (m,5H), 3.96 (s, 3H), 3.82-3.74 (m, 4H), 3.52-3.45(m, 4H).::US9732094, Example 261::US11065253, Example 261	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315840&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954964	383542517							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616627	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 244::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 262::US10172859, Example 129::US9732094, Example 262::US11065253, Example 262	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616629	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-21-3-2-19(30-31-21)24(33)14-10-15(17(26)11-16(14)25)23-22-18(27)8-13(9-20(22)28-12-29-23)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	IPOFTWPZUKXNTC-UHFFFAOYSA-N	315842	US10172859, Example 278::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazoin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 271::US10172859, Example 263::US9732094, Example 278::US11065253, Example 278	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696333	383542518							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616631	Cc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O2S/c1-12-19(26-3-2-25-12)21(30)13-8-14(16(24)9-15(13)23)20-22-17(27-11-28-20)10-18(32-22)29-4-6-31-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	IZJZSFQNGRBZAU-UHFFFAOYSA-N	315843	US10172859, Example 264::[2-Chloro-4-fluoro-5- (6-morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.93 (s,1H), 8.43 (d, J = 2.5, 1H), 8.33 (d, J = 2.4, 1H), 8.11(d, J = 7.9, 1H), 7.63 (d, J = 9.9, 1H), 6.56 (s, 1H),6.47 (d, J = 6.0, 1H), 6.23 (d, J = 4.6 1H), 3.79-3.71 (m, 4H), 3.48-3.39 (m, 4H), 2.73 (s, 3H).::US9732094, Example 264::US11065253, Example 264	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315843&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696430	383542519							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616633	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H20FN5O2S/c1-13-19(25-5-4-24-13)21(29)14-2-3-16(23)15(10-14)20-22-17(26-12-27-20)11-18(31-22)28-6-8-30-9-7-28/h2-5,10-12,21,29H,6-9H2,1H3	JVZGLRHIUDPKQN-UHFFFAOYSA-N	315824	[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 1)see racemate::US10172859, Example 265::US10172859, Example 246::US10172859, Example 245::US9732094, Example 265::US11065253, Example 265	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696361	383542510							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616635	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-24-22(28-2-3-29-24)23(33)14-10-15(17(26)11-16(14)25)21-20-18(27)8-13(9-19(20)30-12-31-21)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	OWOGJPGABWHWIU-UHFFFAOYSA-N	315828	US10172859, Example 266::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 250::US10172859, Example 249::US9732094, Example 266::US11065253, Example 266	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696440	383542512							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616637	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)14-2-3-17(25)16(10-14)21-20-18(26)11-15(12-19(20)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MBESFUDQRFVLFJ-UHFFFAOYSA-N	315831	US10172859, Example 253::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 267::US10172859, Example 252::US9732094, Example 267::US11065253, Example 267	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696418	383542514							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616639	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)17(10-15)23-21-19(26)11-16(12-20(21)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	GCFJFHHQAJXDCA-UHFFFAOYSA-N	315848	US10172859, Example 268::[4-Fluoro-3-(5-fluoro-7-morpholin-4-ylquinazolin-4-yl)phenyl]-(3-methylpyrazin-2-yl)methanol (268), [2-chloro-4-fluoro-5-(5-fluoro-7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol (278)::US9732094, Example 268::US11065253, Example 268	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315848&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696300	383542521							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616641	Cc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C23H20ClFN6O2S/c1-12-20(28-3-2-27-12)19(23(26)32)13-8-14(16(25)9-15(13)24)21-22-17(29-11-30-21)10-18(34-22)31-4-6-33-7-5-31/h2-3,8-11,19H,4-7H2,1H3,(H2,26,32)	YOTHGDNLEVBATQ-UHFFFAOYSA-N	315849	US10172859, Example 269::2-[2-Chloro-4-fluoro- 5-(6-morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 8.87 (s,1H), 8.43 (d, J = 2.6, 1H), 8.40 (d, J = 2.7 1H), 7.82-7.78 (m, 1H), 7.74 (d, J = 10.0, 1H), 7.55 (d,J = 1.78), 7.41-7.36 (m, 1H), 6.53 (s, 1H), 5.63(s, 1H), 3.79-3.73 (m, 3H), 3.43-3.38 (m, 4H),2.51 (s, 3H).::US9732094, Example 269::US11065253, Example 269	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315849&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954872	383542522							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616643	Cc1nccnc1C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C23H21FN6O2S/c1-13-20(27-5-4-26-13)19(23(25)31)14-2-3-16(24)15(10-14)21-22-17(28-12-29-21)11-18(33-22)30-6-8-32-9-7-30/h2-5,10-12,19H,6-9H2,1H3,(H2,25,31)	HFLHZJWDDGOHGW-UHFFFAOYSA-N	315850	US10172859, Example 270::2-[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-6) ppm = 8.88 (s,1H), 8.42-8.37 (m, 2H), 7.67 (dd, J = 7.1, 2.3, 1H),7.61-7.55 (m, 2H), 7.41-7.34 (m, 1H), 7.25-7.19 (m, 1H), 6.53 (s, 1H), 5.40 (s, 1H), 3.79-3.71 (m, 4H), 3.44-3.39 (m, 4H), 2.53 (s, 3H).::US9732094, Example 270::US11065253, Example 270	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315850&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954819	383542523							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616645	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-21-3-2-19(30-31-21)24(33)14-10-15(17(26)11-16(14)25)23-22-18(27)8-13(9-20(22)28-12-29-23)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	IPOFTWPZUKXNTC-UHFFFAOYSA-N	315842	US10172859, Example 278::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazoin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 271::US10172859, Example 263::US9732094, Example 278::US11065253, Example 278	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696333	383542518							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616647	COc1ccc(nn1)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3S/c1-33-18-3-2-16(29-30-18)20(23(26)32)12-8-13(15(25)9-14(12)24)21-22-17(27-11-28-21)10-19(35-22)31-4-6-34-7-5-31/h2-3,8-11,20H,4-7H2,1H3,(H2,26,32)	PCGFSZDYWRXXKO-UHFFFAOYSA-N	315852	US10172859, Example 272::2-[2-Chloro-4-fluoro- 5-(6-morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-2-(6- methoxy-pyridazin-3- yl)acetamide1H NMR (400 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.94 (s, 1H), 7.81 (d, J = 7.7, 1H), 7.74 (d,J = 10.0, 1H), 7.47 (d, J = 9.2, 1H), 7.40 (s, 1H),7.19 (d, J = 9.2, 1H), 6.53 (s, 1H), 5.65 (s, 1H),4.00 (s, 3H), 3.79-3.71 (m, 4H), 3.45-3.39 (m,4H).::US9732094, Example 272::US11065253, Example 272	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315852&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954930	383542524							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616649	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-21-3-2-19(30-31-21)24(33)14-10-15(17(26)11-16(14)25)23-22-18(27)8-13(9-20(22)28-12-29-23)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	IPOFTWPZUKXNTC-UHFFFAOYSA-N	315842	US10172859, Example 278::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazoin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate::US10172859, Example 271::US10172859, Example 263::US9732094, Example 278::US11065253, Example 278	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696333	383542518							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616651	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ncnc12	InChI=1S/C24H20FN7O2/c25-19-4-1-15(23(33)22-24-29-14-30-32(24)6-5-26-22)11-18(19)21-17-3-2-16(12-20(17)27-13-28-21)31-7-9-34-10-8-31/h1-6,11-14,23,33H,7-10H2	FVRXBVVATCNFQH-UHFFFAOYSA-N	315854	US10172859, Example 279::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[1,5-a]- pyrazin-8-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 9.03 (d, J = 4.5, 1H), 8.76 (s, 1H), 8.25 (d,J = 4.5, 1H), 7.84-7.76 (m, 2H), 7.59-7.51 (m,2H), 7.39 (dd, J = 9.9, 8.5, 1H), 7.20 (d, J = 2.1, 1H),6.48 (s, 1H), 3.82-3.75 (m, 4H), 3.51-3.43 (m,4H).::US9732094, Example 279::US11065253, Example 279	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315854	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315854&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954778	383542525							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616653	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ncnc12	InChI=1S/C25H21FN8O2/c26-19-4-1-15(21(24(27)35)23-25-31-14-32-34(25)6-5-28-23)11-18(19)22-17-3-2-16(12-20(17)29-13-30-22)33-7-9-36-10-8-33/h1-6,11-14,21H,7-10H2,(H2,27,35)	ZWRJZLXHRXIIDS-UHFFFAOYSA-N	315855	US10172859, Example 280::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[1,2,4]- triazolo[1,5-a]- pyrazin-8-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 9.02 (d, J = 4.5, 1H), 8.74 (s, 1H), 8.21 (d,J = 4.5, 1H), 7.79-7.75 (m, 1H), 7.74-7.69 (m,2H), 7.64 (dd, J = 9.4, 2.9, 1H), 7.56 (dd, J = 9.5,2.5, 1H), 7.45-7.40 (m, 1H), 7.31-7.27 (m, 1H),7.20 (d, J = 2.4, 1H), 5.89 (s, 1H), 3.81-3.74 (m,4H), 3.49-3.41 (m, 4H).::US9732094, Example 280::US11065253, Example 280	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315855	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315855&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711775	383542526							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616655	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(N3CCOCC3)c(F)cc12	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-19(29-30-22)24(32)14-2-3-17(25)15(10-14)23-16-11-18(26)21(12-20(16)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	DSOJNLMCRNUJKA-UHFFFAOYSA-N	315856	US10172859, Example 282::[4-Fluoro-3-(6-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.24 (s,1H), 7.74-7.63 (m, 3H), 7.48-7.39 (m, 2H),7.34 (dd, J = 13.6, 3.1, 1H), 7.21 (d, J = 9.2, 1H),6.53 (d, J = 4.3, 1H), 6.03 (d, J = 4.4, 1H), 4.00 (s,3H), 3.83-3.77 (m, 4H), 3.36-3.27 (m, 4H).::US9732094, Example 282::US11065253, Example 282	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315856	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315856&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954768	383542527							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616657	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(N3CCOCC3)c(F)cc12	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)16(10-15)23-17-11-19(26)21(12-20(17)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	RSNFZZXIZHWRLL-UHFFFAOYSA-N	315857	US10172859, Example 283::[4-Fluoro-3-(6-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.23 (s,1H), 8.46-8.41 (m, 2H), 7.66-7.58 (m, 2H),7.49-7.31 (m, 3H), 6.32 (d, J = 5.5, 1H), 6.10 (d,J = 5.5, 1H), 3.84-3.78 (m, 4H), 3.36-3.27 (m,4H), 2.57 (s, 3H).::US9732094, Example 283::US11065253, Example 283	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315857&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954979	383542528							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616659	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccsc12	InChI=1S/C26H21FN6O2S/c27-20-4-1-15(22(26(28)34)24-25-16(5-10-36-25)13-31-32-24)11-19(20)23-18-3-2-17(12-21(18)29-14-30-23)33-6-8-35-9-7-33/h1-5,10-14,22H,6-9H2,(H2,28,34)	HBIASEVIOCHSGV-UHFFFAOYSA-N	315858	US10172859, Example 284::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-thieno- [2,3-d}pyridazin-7-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.59 (s,1H), 9.09 (s, 1H), 8.24 (d, J = 5.3, 1H), 7.92 (s,1H), 7.73-7.65 (m, 3H), 7.57 (dd, J = 9.4, 3.1, 1H),7.50 (dd, J = 9.5, 2.5, 1H), 7.47-7.36 (m, 2H),7.19 (d, J = 2.5, 1H), 5.72 (s, 1H), 3.84-3.73 (m,4H), 3.46-3.41 (m, 4H), 9.09-9.09 (m, 0H).::US9732094, Example 284	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315858	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315858&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711746	383542529							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616661	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12	InChI=1S/C26H21FN6O2S/c27-20-4-1-15(23(26(28)34)25-18-5-10-36-22(18)13-31-32-25)11-19(20)24-17-3-2-16(12-21(17)29-14-30-24)33-6-8-35-9-7-33/h1-5,10-14,23H,6-9H2,(H2,28,34)	DQNFYRIXINNVDA-UHFFFAOYSA-N	315859	US10172859, Example 285::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-thieno- [2,3-d}pyridazin-4-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.83-9.79(m, 1H), 9.08 (s, 1H), 8.30 (d, J = 5.4, 1H), 7.81-7.75 (m, 2H), 7.75-7.68 (m, 2H), 7.56 (dd, J = 9.4,3.1, 1H), 7.49 (dd, J = 9.4, 2.6, 1H), 7.40 (dd,J = 9.8, 8.4, 1H), 7.32 (s, 1H), 7.19 (d, J = 2.5, 1H),5.90 (s, 1H), 3.81-3.74 (m, 4H), 3.47-3.40 (m,4H).::US9732094, Example 285::US11065253, Example 285	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315859	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315859&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711776	383542530							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616663	COc1nnc(Cl)cc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-18(12-21(25)29-30-24)23(32)14-2-5-19(26)17(10-14)22-16-4-3-15(11-20(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	PBEWANFAIGVJRA-UHFFFAOYSA-N	315582	US10172859, Example 286::(6-Chloro-5-methoxy- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.88 (d, J = 1.0, 1H), 7.63-7.58 (m, 2H), 7.55- 7.47 (m, 2H), 7.42-7.35 (m, 1H), 7.20 (d, J = 2.3, 1H), 6.46 (d, J = 4.3, 1H), 5.85-5.82 (m, 1H), 4.00 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 9::US9732094, Example 286::US11065253, Example 286	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315582	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315582&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954747	383542341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616665	CN1N=C(CCC1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1 |c:2|	InChI=1S/C24H23ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-3,10-13,24,33H,4-9H2,1H3	FCQKVWFWTHCJBD-UHFFFAOYSA-N	315861	US10172859, Example 288::6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-4,5- dihydro-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.84 (d, J = 7.8, 1H), 7.68 (d, J = 9.5, 1H), 7.57(dd, J = 9.4, 2.8, 1H), 7.54 (dd, J = 9.5, 2.4, 1H),7.21 (d, J = 2.3, 1H), 6.42 (s, 1H), 5.57 (s, 1H),3.81-3.75 (m, 4H), 3.47-3.43 (m, 4H), 3.16 (s,3H), 2.61-2.51 (m, 1H), 2.43-2.28 (m, 3H).::US9732094, Example 288::US11065253, Example 288	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315861	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315861&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954804	383542531							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616667	NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C25H20Cl2FN5O2/c26-18-2-1-5-30-24(18)22(25(29)34)16-11-17(20(28)12-19(16)27)23-15-4-3-14(10-21(15)31-13-32-23)33-6-8-35-9-7-33/h1-5,10-13,22H,6-9H2,(H2,29,34)	YFWBSWOQIFUXES-UHFFFAOYSA-N	315862	US10172859, Example 289::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-chloro- pyridin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.44 (dd, J = 4.7, 1.5, 1H), 7.95 (dd, J = 8.1,1.5, 1H), 7.76 (s, 1H), 7.72 (d, J = 9.6, 1H), 7.58(dd, J = 9.4, 2.9, 1H), 7.54 (dd, J = 9.5, 2.5, 1H),7.41 (d, J = 7.6, 1H), 7.35 (dd, J = 8.1, 4.7, 1H), 7.28(s, 1H), 7.19 (d, J = 2.4, 1H), 5.81 (s, 1H), 3.80-3.75 (m, 4H), 3.48-3.42 (m, 4H).::US9732094, Example 289::US11065253, Example 289	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315862	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315862&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954995	383542532							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616669	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nnc(Cl)c2ccsc12	InChI=1S/C26H20ClFN6O2S/c27-25-17-5-10-37-24(17)23(32-33-25)21(26(29)35)14-1-4-19(28)18(11-14)22-16-3-2-15(12-20(16)30-13-31-22)34-6-8-36-9-7-34/h1-5,10-13,21H,6-9H2,(H2,29,35)	YFPXALXVUKNUIN-UHFFFAOYSA-N	315863	US10172859, Example 290::2-(4-Chlorothieno- [2,3-d}pyridazin-7-yl)- 2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.41 (d, J = 5.4, 1H), 7.94 (s, 1H), 7.71-7.65(m, 3H), 7.56 (dd, J = 9.4, 3.1, 1H), 7.51 (dd,J = 9.4, 2.5, 1H), 7.48-7.40 (m, 2H), 7.20 (d,J = 2.4, 1H), 5.75 (s, 1H), 3.82-3.73 (m, 4H), 3.48-3.40 (m, 4H).::US9732094, Example 290::US11065253, Example 290	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315863&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954780	383542533							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616671	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nnc(Cl)c2sccc12	InChI=1S/C26H20ClFN6O2S/c27-25-24-17(5-10-37-24)23(32-33-25)21(26(29)35)14-1-4-19(28)18(11-14)22-16-3-2-15(12-20(16)30-13-31-22)34-6-8-36-9-7-34/h1-5,10-13,21H,6-9H2,(H2,29,35)	ZYLBIZICFDLWPM-UHFFFAOYSA-N	315864	US10172859, Example 291::2-(7-Chlorothieno- [2,3-d}pyridazin-4-yl)- 2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.43 (d, J = 5.4, 1H), 7.86 (d, J = 5.4, 1H), 7.77(s, 1H), 7.74-7.67 (m, 2H), 7.56 (dd, J = 9.4, 3.1,1H), 7.50 (dd, J = 9.5, 2.5, 1H), 7.44-7.35 (m, 2H),7.19 (d, J = 2.4, 1H), 5.92 (s, 1H), 3.81-3.74 (m,4H), 3.47-3.40 (m, 4H).::US9732094, Example 291::US11065253, Example 291	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315864	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315864&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711726	383542534							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616673	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(n1)C(N)=O	InChI=1S/C25H22FN7O3/c26-18-4-1-14(22(25(28)35)20-11-29-12-21(32-20)24(27)34)9-17(18)23-16-3-2-15(10-19(16)30-13-31-23)33-5-7-36-8-6-33/h1-4,9-13,22H,5-8H2,(H2,27,34)(H2,28,35)	XBPHXCUOKRHJAU-UHFFFAOYSA-N	315865	US10172859, Example 292::6-{Carbamoyl-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methyl}- pyrazine-2-carboxylic acid amide1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 9.06 (s, 1H), 8.90 (s, 1H), 8.08-8.01 (m,1H), 7.99-7.93 (m, 1H), 7.85-7.77 (m, 2H),7.77-7.71 (m, 1H), 7.59 (dd, J = 9.4, 3.6, 1H),7.52 (dd, J = 9.5, 2.5, 1H), 7.46-7.39 (m, 1H),7.38-7.32 (m, 1H), 7.20 (d, J = 2.5, 1H), 5.39 (s,1H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H).::US9732094, Example 292::US11065253, Example 292	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315865	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315865&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711808	383542535							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616675	NC(=O)C(c1cccnc1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN5O2/c26-20-12-21(27)19(11-18(20)23(25(28)33)15-2-1-5-29-13-15)24-17-4-3-16(10-22(17)30-14-31-24)32-6-8-34-9-7-32/h1-5,10-14,23H,6-9H2,(H2,28,33)	FJSRWVIDUQOPMH-UHFFFAOYSA-N	315866	US10172859, Example 293::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridin-3- ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.49 (s, 1H), 8.46 (d, J = 3.9, 1H), 7.94 (s,1H), 7.74 (d, J = 9.5, 1H), 7.67 (d, J = 7.7, 1H), 7.66-7.63 (m, 1H), 7.56 (dd, J = 9.4, 4.8, 1H), 7.53 (s,J = 9.5, 2.4, 1H), 7.37 (dd, J = 7.9, 4.8, 1H), 7.33 (s,1H), 7.20 (d, J = 2.3, 1H), 5.41 (s, 1H), 3.81-3.74(m, 4H), 3.49-3.42 (m, 4H).::US9732094, Example 293::US11065253, Example 293	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315866&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954991	383542536							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616677	NC(=O)C(c1cccnc1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N5O2/c26-20-12-21(27)19(11-18(20)23(25(28)33)15-2-1-5-29-13-15)24-17-4-3-16(10-22(17)30-14-31-24)32-6-8-34-9-7-32/h1-5,10-14,23H,6-9H2,(H2,28,33)	VMDULKVFFKUUBT-UHFFFAOYSA-N	315867	US10172859, Example 294::2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridin-3- ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.53 (d, J = 2.3, 1H), 8.48 (dd, J = 4.8, 1.6, 1H),7.89 (s, 1H), 7.72 (dt, J = 8.0, 2.0, 1H), 7.61 (t,J = 8.2, 1H), 7.59-7.48 (m, 3H), 7.38 (dd, J = 7.9,4.7, 1H), 7.32 (s, 1H), 7.19 (d, J = 2.3, 1H), 5.31(s, 1H), 3.82-3.73 (m, 4H), 3.47-3.42 (m, 4H).::US9732094, Example 294::US11065253, Example 294	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315867&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711804	383542537							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616679	NC(=O)C(c1cccnc1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN5O2/c26-21-6-3-16(23(25(27)32)17-2-1-7-28-14-17)12-20(21)24-19-5-4-18(13-22(19)29-15-30-24)31-8-10-33-11-9-31/h1-7,12-15,23H,8-11H2,(H2,27,32)	HARXJYPHARBMGT-UHFFFAOYSA-N	315868	US10172859, Example 295::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridin-3- ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.55 (s, 1H), 8.47 (s, 1H), 7.82 (s, 1H), 7.79(d, J = 8.0, 1H), 7.62-7.56 (m, 2H), 7.56-7.49 (m,2H), 7.45-7.35 (m, 2H), 7.25 (s, 1H), 7.20 (d,J = 2.0, 1H), 5.12 (s, 1H), 3.80-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US9732094, Example 295::US11065253, Example 295	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315868&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954838	383542538							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616681	Cc1cncc(n1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-12-26-13-22(29-15)24(31)16-2-5-20(25)19(10-16)23-18-4-3-17(11-21(18)27-14-28-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	ORSZUBJYTOFBKJ-UHFFFAOYSA-N	315869	US10172859, Example 296::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.66 (s, 1H), 8.43 (s, 1H), 7.68-7.63 (m,2H), 7.54-7.49 (m, 2H), 7.42-7.35 (m, 1H),7.21-7.18 (m, 1H), 6.40 (d, J = 4.3, 1H), 5.87 (d,J = 4.3, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m,4H), 2.46 (s, 3H).::US9732094, Example 296::US11065253, Example 296	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315869&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954831	383542539							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616683	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(Cl)c1	InChI=1S/C25H21ClFN5O2/c26-17-9-16(12-29-13-17)23(25(28)33)15-1-4-21(27)20(10-15)24-19-3-2-18(11-22(19)30-14-31-24)32-5-7-34-8-6-32/h1-4,9-14,23H,5-8H2,(H2,28,33)	IVXXOGNVDFQXBW-UHFFFAOYSA-N	315870	US10172859, Example 297::2-(5-Chloro-pyridin- 3-yl)-2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.54 (d, J = 2.4, 1H), 8.52 (d, J = 1.9, 1H), 7.90-7.87 (m, 1H), 7.85 (s, 1H), 7.61 (tt, J = 6.9, 2.3,2H), 7.53 (qd, J = 9.4, 2.8, 2H), 7.47-7.39 (m, 1H),7.33 (s, 1H), 7.20 (d, J = 2.3, 1H), 5.16 (s, 1H),3.82-3.73 (m, 4H), 3.48-3.40 (m, 4H).::US9732094, Example 297::US11065253, Example 297	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315870&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711747	383542540							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616685	NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccc2nncn12	InChI=1S/C26H21ClFN7O2/c27-19-12-20(28)18(11-17(19)24(26(29)36)22-2-1-3-23-33-32-14-35(22)23)25-16-5-4-15(10-21(16)30-13-31-25)34-6-8-37-9-7-34/h1-5,10-14,24H,6-9H2,(H2,29,36)	MUPNGTJETJQOSB-UHFFFAOYSA-N	315871	US10172859, Example 298::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.21 (d,J = 0.8, 1H), 9.08 (s, 1H), 8.13 (s, 1H), 7.88 (d,J = 9.5, 1H), 7.79 (d, J = 9.2, 1H), 7.73 (s, 1H), 7.57-7.48 (m, 3H), 7.38 (dd, J = 9.2, 6.9, 1H), 7.19 (d,J = 2.3, 1H), 6.57 (d, J = 6.9, 1H), 5.84 (s, 1H), 3.80-3.75 (m, 4H), 3.48-3.42 (m, 4H).::US9732094, Example 298	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315871	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954996	383542541							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616687	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C26H22FN7O2/c27-20-6-3-16(23(26(28)35)25-22-2-1-7-34(22)32-15-31-25)12-19(20)24-18-5-4-17(13-21(18)29-14-30-24)33-8-10-36-11-9-33/h1-7,12-15,23H,8-11H2,(H2,28,35)	ZMIMJRGRWXTILZ-UHFFFAOYSA-N	315872	US10172859, Example 299::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyrrolo- [2,1-f][1,2,4]triazin-4- ylacetamide::US9732094, Example 299::US11065253, Example 299	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315872&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711729	383542542							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616689	NC(=O)C(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20ClFN6O2/c25-18-12-19(26)17(11-16(18)22(24(27)33)20-2-1-5-30-31-20)23-15-4-3-14(10-21(15)28-13-29-23)32-6-8-34-9-7-32/h1-5,10-13,22H,6-9H2,(H2,27,33)	GVAJWRHXZHKFPU-UHFFFAOYSA-N	315873	US10172859, Example 300::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridazin- 3-ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd,J = 4.9, 1.6, 1H), 9.10 (s, 1H), 8.03 (s, 1H), 7.76(d, J = 9.6, 1H), 7.71 (d, J = 7.6, 1H), 7.65 (dd,J = 8.5, 4.9, 1H), 7.60 (dd, J = 9.4, 3.4, 1H), 7.53(dd, J = 5.6, 2.1, 1H), 7.52 (dd, J = 4.7, 2.0, 1H),7.43 (s, 1H), 7.20 (d, J = 2.5, 1H), 5.78 (s, 1H),3.78 (dd, J = 5.8, 4.0, 4H), 3.46 (dd, J = 6.0, 3.9, 4H).::US9732094, Example 300::US11065253, Example 300	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954908	383542543							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616691	Cc1cnc(C(C(N)=O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C26H24ClFN6O2/c1-14-12-30-24(15(2)33-14)23(26(29)35)18-10-19(21(28)11-20(18)27)25-17-4-3-16(9-22(17)31-13-32-25)34-5-7-36-8-6-34/h3-4,9-13,23H,5-8H2,1-2H3,(H2,29,35)	YREBEWXOGBLYAA-UHFFFAOYSA-N	315874	US10172859, Example 301::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3,5- dimethyl-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.25 (s, 1H), 7.75-7.69 (m, 2H), 7.58 (dd,J = 9.4, 3.0, 1H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.47 (d,J = 7.7, 1H), 7.28 (s, 1H), 7.19 (d, J = 2.4, 1H), 5.60(s, 1H), 3.81-3.74 (m, 4H), 3.49-3.42 (m, 4H),2.49 (s, 3H), 2.41 (s, 3H).::US9732094, Example 301::US11065253, Example 301	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315874&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954954	383542544							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616693	Nc1cncc(n1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN6O2/c24-18-4-1-14(23(31)20-11-26-12-21(25)29-20)9-17(18)22-16-3-2-15(10-19(16)27-13-28-22)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2,(H2,25,29)	NIRGTHULFDHQGA-UHFFFAOYSA-N	315875	US10172859, Example 302::(6-Amino-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.91 (s, 1H), 7.74 (s, 1H), 7.63-7.56 (m,2H), 7.54-7.51 (m, 2H), 7.39-7.34 (m, 1H),7.21-7.19 (m, 1H), 6.36 (s, 2H), 6.10 (d, J = 4.3,1H), 5.60 (d, J = 4.3, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US9732094, Example 302::US11065253, Example 302	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315875&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954786	383542545							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616695	Cc1nccnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-23(29-7-6-28-15)22(25(27)33)19-12-16(2-5-20(19)26)24-18-4-3-17(13-21(18)30-14-31-24)32-8-10-34-11-9-32/h2-7,12-14,22H,8-11H2,1H3,(H2,27,33)	HFSXUJIMPFGNPH-UHFFFAOYSA-N	315876	US10172859, Example 303::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.43-8.37 (m, 2H), 7.87 (d, J = 9.4, 1H), 7.80(s, 1H), 7.75-7.65 (m, 3H), 7.51 (dd, J = 9.5, 2.6,1H), 7.33 (s, 1H), 7.19 (d, J = 2.5, 1H), 5.71 (s,1H), 3.85-3.74 (m, 4H), 3.52-3.39 (m, 4H),2.55 (s, 3H).::US9732094, Example 303::US11065253, Example 303	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954878	383542546							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616697	COc1nccnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O3/c1-34-25-23(28-6-7-29-25)21(24(27)33)18-12-15(2-5-19(18)26)22-17-4-3-16(13-20(17)30-14-31-22)32-8-10-35-11-9-32/h2-7,12-14,21H,8-11H2,1H3,(H2,27,33)	PYCHWQUCZXHTRJ-UHFFFAOYSA-N	315877	US10172859, Example 304::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 8.12 (d, J = 2.8, 1H), 8.10 (d, J = 2.8, 1H), 7.89(d, J = 9.4, 1H), 7.79-7.75 (m, 1H), 7.73-7.69 (m,2H), 7.67 (d, J = 8.1, 1H), 7.52 (dd, J = 9.5, 2.6, 1H),7.27-7.23 (m, 1H), 7.20 (d, J = 2.6, 1H), 5.71 (s,1H), 3.95 (s, 3H), 3.81-3.75 (m, 4H), 3.49-3.41(m, 4H).::US9732094, Example 304::US11065253, Example 304	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315877&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954818	383542547							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616699	COc1nccnc1C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-34-25-23(28-6-7-29-25)21(24(27)33)15-2-5-19(26)18(12-15)22-17-4-3-16(13-20(17)30-14-31-22)32-8-10-35-11-9-32/h2-7,12-14,21H,8-11H2,1H3,(H2,27,33)	WTJREBFFELNABQ-UHFFFAOYSA-N	315878	US10172859, Example 305::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.13 (d, J = 2.8, 1H), 8.10 (d, J = 2.8, 1H), 7.63(dd, J = 9.4, 2.8, 1H), 7.61-7.52 (m, 4H), 7.41-7.35 (m, 1H), 7.20 (d, J = 2.4, 1H), 7.11 (s, 1H),5.34 (s, 1H), 3.93 (s, 3H), 3.82-3.74 (m, 4H),3.48-3.41 (m, 4H).::US9732094, Example 305::US11065253, Example 305	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315878&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954938	383542548							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616701	COc1ccc(nn1)C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O3/c1-35-22-5-4-20(31-32-22)23(25(28)34)16-11-17(19(27)12-18(16)26)24-15-3-2-14(10-21(15)29-13-30-24)33-6-8-36-9-7-33/h2-5,10-13,23H,6-9H2,1H3,(H2,28,34)	SVGLXBJVNLMNGP-UHFFFAOYSA-N	315879	US10172859, Example 306::2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxy-pyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.90 (s, 1H), 7.71 (t, J = 8.2, 1H), 7.61-7.49(m, 4H), 7.37 (s, 1H), 7.20 (d, J = 2.4, 1H), 7.18 (d,J = 9.2, 1H), 5.57 (s, 1H), 4.00 (s, 3H), 3.81-3.74(m, 4H), 3.49-3.41 (m, 4H).::US9732094, Example 306::US11065253, Example 306	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315879	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315879&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954932	383542549							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616703	COc1nnccc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-35-25-16(4-5-31-32-25)22(24(28)34)17-11-18(20(27)12-19(17)26)23-15-3-2-14(10-21(15)29-13-30-23)33-6-8-36-9-7-33/h2-5,10-13,22H,6-9H2,1H3,(H2,28,34)	MYBWUZUNIOXSID-UHFFFAOYSA-N	315880	US10172859, Example 307::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxypyridazin-4- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.80 (d, J = 4.7, 1H), 8.02 (s, 1H), 7.80 (d,J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H), 7.53 (dd,J = 9.5, 2.5, 1H), 7.46 (d, J = 7.5, 1H), 7.42 (s, 1H),7.20 (d, J = 2.4, 1H), 7.08 (dd, J = 4.7, 0.5, 1H), 5.46(s, 1H), 4.07 (s, 3H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H).::US9732094, Example 307::US11065253, Example 307	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315880	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315880&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954902	383542550							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616705	COc1ccc(nn1)C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-34-22-7-6-20(30-31-22)23(25(27)33)15-2-5-19(26)18(12-15)24-17-4-3-16(13-21(17)28-14-29-24)32-8-10-35-11-9-32/h2-7,12-14,23H,8-11H2,1H3,(H2,27,33)	ISTYTDDGDVSFKS-UHFFFAOYSA-N	315881	US10172859, Example 308::2-[4-Fluoro-3-(7- morpolin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxypyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.87 (s, 1H), 7.67 (d, J = 9.2, 1H), 7.64-7.57(m, 2H), 7.57-7.49 (m, 2H), 7.46-7.38 (m, 1H),7.31 (s, 1H), 7.20 (d, J = 2.2, 1H), 7.18 (d, J = 9.2,1H), 5.40 (s, 1H), 4.00 (s, 3H), 3.78 (dd, J = 5.8,3.9, 4H), 3.44 (dd, J = 5.8, 4.1, 4H).::US9732094, Example 308::US11065253, Example 308	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315881	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315881&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954945	383542551							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616707	NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C26H21ClFN7O2/c27-19-12-20(28)18(11-17(19)23(26(29)36)25-22-2-1-5-35(22)33-14-32-25)24-16-4-3-15(10-21(16)30-13-31-24)34-6-8-37-9-7-34/h1-5,10-14,23H,6-9H2,(H2,29,36)	LXBZRTFPUMGGNZ-UHFFFAOYSA-N	315882	US10172859, Example 309::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[3H- pyrrolo[2,1-f][1,2,4]- triazin-(4E)-ylidene]- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 13.76 (d,J = 3.9, 1H), 9.07 (s, 1H), 7.86 (d, J = 9.7, 1H), 7.84-7.76 (m, 2H), 7.56 (d, J = 7.8, 1H), 7.51 (dd,J = 9.5, 2.5, 1H), 7.32 (dd, J = 2.7, 1.7, 1H), 7.18 (d,J = 2.4, 1H), 6.99 (s, 1H), 6.37 (s, 1H), 6.26 (dd,J = 4.4, 2.7, 1H), 4.87 (dd, J = 4.4, 1.7, 1H), 3.81-3.74 (m, 4H), 3.49-3.42 (m, 4H).::US9732094, Example 309::US11065253, Example 309	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315882&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966399	383542552							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616709	COc1ccc(nn1)C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O3/c1-34-22-7-6-20(30-31-22)23(25(27)33)18-12-15(2-5-19(18)26)24-17-4-3-16(13-21(17)28-14-29-24)32-8-10-35-11-9-32/h2-7,12-14,23H,8-11H2,1H3,(H2,27,33)	JNCOXIXWPDKVLE-UHFFFAOYSA-N	315883	US10172859, Example 310::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxy-pyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.97 (s, 1H), 7.89-7.85 (m, 2H), 7.73 (dd,J = 8.2, 2.1, 1H), 7.70 (d, J = 8.2, 1H), 7.52 (dd,J = 9.5, 2.6, 1H), 7.46 (d, J = 9.2, 1H), 7.39 (s, 1H),7.21 (d, J = 2.5, 1H), 7.18 (d, J = 9.2, 1H), 5.72 (s,1H), 4.01 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.42(m, 4H).::US9732094, Example 310::US11065253, Example 310	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315883	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315883&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954980	383542553							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616711	Cn1nc(ccc1=O)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-32-22(34)5-4-20(31-32)23(25(28)35)16-11-17(19(27)12-18(16)26)24-15-3-2-14(10-21(15)29-13-30-24)33-6-8-36-9-7-33/h2-5,10-13,23H,6-9H2,1H3,(H2,28,35)	JMVHOQVMAZGVSV-UHFFFAOYSA-N	315884	US10172859, Example 311::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1-methyl- 6-oxo-1,6-dihydro- pyridazin-3-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.92 (s, 1H), 7.76 (d, J = 9.5, 1H), 7.68 (d,J = 7.5, 1H), 7.58 (dd, J = 9.4, 3.1, 1H), 7.54 (dd,J = 9.5, 2.5, 1H), 7.41 (s, 1H), 7.33 (d, J = 9.6, 1H),7.21 (d, J = 2.4, 1H), 6.90 (d, J = 9.6, 1H), 5.33 (s,1H), 3.81-3.75 (m, 4H), 3.59 (s, 3H), 3.49-3.42(m, 4H).::US9732094, Example 311::US11065253, Example 311	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315884	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315884&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954843	383542554							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616713	Cn1c(cccc1=O)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O3/c1-32-22(3-2-4-23(32)34)24(26(29)35)17-12-18(20(28)13-19(17)27)25-16-6-5-15(11-21(16)30-14-31-25)33-7-9-36-10-8-33/h2-6,11-14,24H,7-10H2,1H3,(H2,29,35)	HIJPXJUNOMZZGM-UHFFFAOYSA-N	315885	US10172859, Example 312::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1-methyl- 6-oxo-1,6-dihydro- pyridin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.04 (s, 1H), 7.83 (d, J = 9.4, 1H), 7.62-7.44(m, 3H), 7.42-7.27 (m, 2H), 7.19 (d, J = 2.4, 1H),6.36 (dd, J = 9.1, 1.3, 1H), 5.90 (dd, J = 7.1, 1.3, 1H),5.48 (s, 1H), 3.77 (dd, J = 5.8, 4.0, 4H), 3.52-3.42(m, 4H), 3.40 (s, 3H).::US9732094, Example 312::US11065253, Example 312	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315885&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954733	383542555							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616715	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C25H21ClFN5O2/c26-19-2-1-7-29-24(19)22(25(28)33)15-3-6-20(27)18(12-15)23-17-5-4-16(13-21(17)30-14-31-23)32-8-10-34-11-9-32/h1-7,12-14,22H,8-11H2,(H2,28,33)	ODLAGNXUZAQEJQ-UHFFFAOYSA-N	315886	US10172859, Example 313::2-(3-Chloro-pyridin- 2-yl)-2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.51 (dd, J = 4.7, 1.5, 1H), 7.93 (dd, J = 8.1,1.5, 1H), 7.64 (dd, J = 9.4, 2.9, 1H), 7.61-7.53 (m,4H), 7.39 (dd, J = 9.9, 8.7, 1H), 7.36 (dd, J = 8.1,4.7, 1H), 7.21 (d, J = 2.5, 1H), 7.17 (s, 1H), 5.53(s, 1H), 3.84-3.73 (m, 4H), 3.50-3.41 (m, 4H).::US9732094, Example 313::US11065253, Example 313	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315886	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315886&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711751	383542556							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616717	Cc1ncc(nc1C)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O2/c1-15-16(2)30-23(13-27-15)25(32)17-3-6-21(26)20(11-17)24-19-5-4-18(12-22(19)28-14-29-24)31-7-9-33-10-8-31/h3-6,11-14,25,32H,7-10H2,1-2H3	IEKSFLLJQVYYRD-UHFFFAOYSA-N	315887	US10172859, Example 314::(5,6-Dimethyl- pyrazin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-6) ppm = 9.09 (s,1H), 8.51 (s, 1H), 7.66-7.61 (m, 2H), 7.54-7.49(m, 2H), 7.40-7.35 (m, 1H), 7.21-7.19 (m, 1H),6.32 (d, J = 4.2, 1H), 5.84 (d, J = 4.0, 1H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H), 2.45 (s, 3H),2.44 (s, 3H).::US9732094, Example 314::US11065253, Example 314	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315887	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315887&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954958	383542557							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616719	NC(=O)C(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C24H20Cl2N6O2/c25-18-4-1-14(11-17(18)20(24(27)33)22-23(26)29-6-5-28-22)21-16-3-2-15(12-19(16)30-13-31-21)32-7-9-34-10-8-32/h1-6,11-13,20H,7-10H2,(H2,27,33)	LGURFCDOKAGGDY-UHFFFAOYSA-N	315888	US10172859, Example 315::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-chloro- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.60 (d, J = 2.5, 1H), 8.45 (d, J = 2.5, 1H), 7.97-7.91 (m, 1H), 7.88 (d, J = 9.5, 1H), 7.75 (dd,J = 8.3, 2.1, 1H), 7.71 (d, J = 8.2, 1H), 7.66 (d,J = 2.1, 1H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.47-7.42(m, 1H), 7.22-7.19 (m, 1H), 5.87 (s, 1H), 3.81-3.76 (m, 4H), 3.47-3.42 (m, 4H).::US9732094, Example 315::US11065253, Example 315	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315888	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315888&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954816	383542558							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616721	COc1nccnc1C(C(N)=O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-34-25-23(28-6-7-29-25)21(24(27)33)18-12-15(2-5-19(18)26)22-17-4-3-16(13-20(17)30-14-31-22)32-8-10-35-11-9-32/h2-7,12-14,21H,8-11H2,1H3,(H2,27,33)	WFFVFJGDUOBPBZ-UHFFFAOYSA-N	315889	US10172859, Example 316::2-[2-Fluoro-5-(7- morpholin-4-yl)- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.13 (d, J = 2.9, 2H), 7.94 (d, J = 9.4, 1H), 7.78-7.70 (m, 3H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.41 (dd,J = 9.6, 8.6, 1H), 7.23 (s, 1H), 7.19 (d, J = 2.5, 1H),5.59 (s, 1H), 3.95 (s, 3H), 3.82-3.74 (m, 4H),3.48-3.40 (m, 4H).::US11065253, Example 316	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315889&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954769	383542559							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616723	Cn1nc(ccc1=O)C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-31-22(33)7-6-20(30-31)23(25(27)34)15-2-5-19(26)18(12-15)24-17-4-3-16(13-21(17)28-14-29-24)32-8-10-35-11-9-32/h2-7,12-14,23H,8-11H2,1H3,(H2,27,34)	AJGVVTLBHUTRNF-UHFFFAOYSA-N	315890	US10172859, Example 317::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1-methyl- 6-oxo-1,6-dihydro- pyridazin-3-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.86 (s, 1H), 7.64-7.50 (m, 4H), 7.47 (d,J = 9.6, 1H), 7.44 (dd, J = 9.8, 8.5, 1H), 7.34 (s, 1H),7.20 (d, J = 2.2, 1H), 6.90 (d, J = 9.6, 1H), 5.05 (s,1H), 3.83-3.73 (m, 4H), 3.61 (s, 3H), 3.44 (t,J = 4.9, 4H).::US9732094, Example 317::US11065253, Example 317	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315890	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315890&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954966	383542560							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616725	Cc1cnc(C(C(N)=O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C26H25FN6O2/c1-15-13-29-24(16(2)32-15)23(26(28)34)17-3-6-21(27)20(11-17)25-19-5-4-18(12-22(19)30-14-31-25)33-7-9-35-10-8-33/h3-6,11-14,23H,7-10H2,1-2H3,(H2,28,34)	NRRQWZVQONPIET-UHFFFAOYSA-N	315893	US10172859, Example 318::2-(3,5-Dimethyl- pyrazin-2-yl)-2-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.29 (s, 1H), 7.60 (dd, J = 9.5, 2.9, 1H), 7.59-7.55 (m, 2H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.50 (s,1H), 7.42-7.33 (m, 1H), 7.20 (d, J = 2.5, 1H), 7.15(s, 1H), 5.35 (s, 1H), 3.78 (dd, J = 5.8, 4.0, 4H),3.44 (dd, J = 6.0, 3.9, 4H), 2.49 (s, 3H), 2.41 (s,3H).::US9732094, Example 318::US11065253, Example 318	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315893	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315893&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711771	383542563							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616727	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O3/c1-35-25-23(29-4-5-30-25)21(24(28)34)16-11-17(19(27)12-18(16)26)22-15-3-2-14(10-20(15)31-13-32-22)33-6-8-36-9-7-33/h2-5,10-13,21H,6-9H2,1H3,(H2,28,34)	RKXNBPNEHZAEBV-UHFFFAOYSA-N	315894	US10172859, Example 319::2-[2,4-Difluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-2-(3-methoxypyrazin-2-yl)-acetamide ::US9732094, Example 316::US11065253, Example 319	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315894	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315894&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696606	383542564							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616729	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-35-25-23(29-4-5-30-25)21(24(28)34)16-11-17(19(27)12-18(16)26)22-15-3-2-14(10-20(15)31-13-32-22)33-6-8-36-9-7-33/h2-5,10-13,21H,6-9H2,1H3,(H2,28,34)	YUXKXBCAYRFJNK-UHFFFAOYSA-N	315895	US10172859, Example 320::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.12 (d, J = 2.8, 1H), 8.09 (d, J = 2.8, 1H), 7.78(s, 1H), 7.72 (d, J = 9.6, 1H), 7.60 (dd, J = 9.4, 3.1,1H), 7.55 (dd, J = 9.5, 2.5, 1H), 7.51 (d, J = 7.6, 1H),7.26 (s, 1H), 7.20 (d, J = 2.4, 1H), 5.65 (s, 1H),3.95 (s, 3H), 3.86-3.66 (m, 4H), 3.56-3.37 (m,4H).::US9732094, Example 320::US11065253, Example 320	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315895	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315895&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954886	383542565							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616731	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(F)cncc1F	InChI=1S/C25H20F3N5O2/c26-18-4-1-14(22(25(29)34)23-19(27)11-30-12-20(23)28)9-17(18)24-16-3-2-15(10-21(16)31-13-32-24)33-5-7-35-8-6-33/h1-4,9-13,22H,5-8H2,(H2,29,34)	IJRREKAUYFBFNQ-UHFFFAOYSA-N	315897	US10172859, Example 321::2-(3,5-Difluoro- pyridin-4-yl)-2-[2- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.50 (s, 2H), 7.59 (s, 1H), 7.58-7.49 (m,4H), 7.46-7.37 (m, 2H), 7.20 (d, J = 2.2, 1H), 5.42(s, 1H), 3.87-3.64 (m, 4H), 3.59-3.40 (m, 4H).::US9732094, Example 321::US11065253, Example 321	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315897	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315897&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711728	383542567							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616733	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(F)c1Cl	InChI=1S/C25H20ClF2N5O2/c26-23-18(11-30-12-20(23)28)22(25(29)34)14-1-4-19(27)17(9-14)24-16-3-2-15(10-21(16)31-13-32-24)33-5-7-35-8-6-33/h1-4,9-13,22H,5-8H2,(H2,29,34)	OVKBRTLIPKHGGE-UHFFFAOYSA-N	315898	US10172859, Example 322::2-(4-Chloro-5-fluoro- pyridin-3-yl)-2-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (d,J = 2.3, 1H), 8.65 (s, 1H), 8.33 (s, 1H), 7.94 (s,1H), 7.61-7.50 (m, 4H), 7.44 (dt, J = 20.5, 9.0,2H), 7.20 (d, J = 2.1, 1H), 5.44 (s, 1H), 3.80-3.75(m, 4H), 3.47-3.42 (m, 4H).::US9732094, Example 322::US11065253, Example 322	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315898&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954801	383542568							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616735	NC(=O)C(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H21ClFN7O2/c27-19-13-20(28)18(12-17(19)24(26(29)36)21-3-4-23-30-5-6-35(23)33-21)25-16-2-1-15(11-22(16)31-14-32-25)34-7-9-37-10-8-34/h1-6,11-14,24H,7-10H2,(H2,29,36)	OJEWVMZBLXICGN-UHFFFAOYSA-N	315899	US10172859, Example 323::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-imidazo- [1,2-b]pyridazin-6-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (d,J = 10.0, 1H), 8.24 (s, 1H), 8.08 (d, J = 9.5, 1H),8.02 (s, 1H), 7.79 (d, J = 9.5, 1H), 7.76 (d, J = 1.2,1H), 7.72 (d, J = 7.6, 1H), 7.60 (dd, J = 9.5, 3.2, 1H),7.53 (dd, J = 9.5, 2.5, 1H), 7.47 (s, 1H), 7.22 (d,J = 2.5, 1H), 7.11 (d, J = 9.5, 1H), 5.61 (s, 1H), 3.81-3.74 (m, 4H), 3.49-3.42 (m, 4H).::US9732094, Example 323::US11065253, Example 323	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315899&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954761	383542569							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616737	Cc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O2/c1-14-23(30-5-4-29-14)22(25(28)34)17-11-18(20(27)12-19(17)26)24-16-3-2-15(10-21(16)31-13-32-24)33-6-8-35-9-7-33/h2-5,10-13,22H,6-9H2,1H3,(H2,28,34)	YYPSKFJTJFGDAL-UHFFFAOYSA-N	315900	US10172859, Example 324::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.40 (d, J = 2.5, 1H), 8.38 (d, J = 2.5, 1H), 7.80(s, 1H), 7.73 (d, J = 9.5, 1H), 7.59 (dd, J = 9.5, 3.0,1H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.48 (d, J = 7.6, 1H),7.34 (s, 1H), 7.19 (d, J = 2.4, 1H), 5.66 (s, 1H),3.78 (dd, J = 5.8, 4.0, 4H), 3.45 (dd, J = 5.9, 3.9, 4H),2.55 (s, 3H).::US9732094, Example 324::US11065253, Example 324	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315900&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954876	383542570							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616739	COc1ccc(nn1)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-35-22-5-4-20(31-32-22)23(25(28)34)16-11-17(19(27)12-18(16)26)24-15-3-2-14(10-21(15)29-13-30-24)33-6-8-36-9-7-33/h2-5,10-13,23H,6-9H2,1H3,(H2,28,34)	DYZAPEQQSGHKFC-UHFFFAOYSA-N	315901	US10172859, Example 325::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxypyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.96 (s, 1H), 7.75 (d, J = 9.5, 1H), 7.71 (d,J = 7.6, 1H), 7.63-7.51 (m, 2H), 7.47 (d, J = 9.21H), 7.39 (s, 1H), 7.21 (d, J = 2.4, 1H), 7.17 (d,J = 9.2, 1H), 5.67 (s, 1H), 4.00 (s, 3H), 3.82-3.74(m, 4H), 3.50-3.42 (m, 4H).::US9732094, Example 325	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315901&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954997	383542571							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616741	Cn1nc(ccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-29-22(31)7-6-20(28-29)24(32)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,32H,8-11H2,1H3	HTZWBDYETOMOMW-UHFFFAOYSA-N	315902	US10172859, Example 326::6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.66-7.60 (m, 2H), 7.55-7.49 (m, 2H),7.47 (d, J = 9.6, 1H), 7.44-7.39 (m, 1H), 7.21-7.19 (m, 1H), 6.93 (d, J = 9.6, 1H), 6.46 (d, J = 4.3,1H), 5.66 (d, J = 4.3, 1H), 3.80-3.75 (m, 4H), 3.62(s, 3H), 3.46-3.42 (m, 4H).::US9732094, Example 326::US11065253, Example 326	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315902&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954783	383542572							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616743	Cc1nccnc1C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O2/c1-15-23(29-7-6-28-15)22(25(27)33)16-2-5-20(26)19(12-16)24-18-4-3-17(13-21(18)30-14-31-24)32-8-10-34-11-9-32/h2-7,12-14,22H,8-11H2,1H3,(H2,27,33)	SXTFNSCSKUHTAF-UHFFFAOYSA-N	315903	US10172859, Example 327::2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.41 (d, J = 2.4, 1H), 8.38 (d, J = 2.6, 1H), 7.64-7.51 (m, 5H), 7.38 (dd, J = 10.6, 8.5, 1H), 7.21-7.16 (m, 2H), 5.41 (s, 1H), 3.83-3.74 (m, 4H),3.46-3.40 (m, 4H), 2.54 (s, 3H).::US9732094, Example 327::US11065253, Example 327	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315903&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954849	383542573							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616745	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccc2ccoc12	InChI=1S/C26H21FN4O3/c27-21-4-1-17(25(32)24-26-16(5-7-28-24)6-10-34-26)13-20(21)23-19-3-2-18(14-22(19)29-15-30-23)31-8-11-33-12-9-31/h1-7,10,13-15,25,32H,8-9,11-12H2	XGIZNDWBXPNXFQ-UHFFFAOYSA-N	315904	US10172859, Example 328::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-c]- pyridin-7-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.32 (d, J = 5.2, 1H), 8.21 (d, J = 2.2, 1H), 7.74-7.67 (m, 2H), 7.64 (d, J = 5.2, 1H), 7.52-7.49 (m,2H), 7.36 (dd, J = 9.9, 8.4, 1H), 7.22-7.16 (m, 1H),7.06 (d, J = 2.2, 1H), 6.32 (d, J = 5.0, 1H), 6.25 (d,J = 5.0, 1H), 3.80-3.75 (m, 4H), 3.46-3.41 (m,4H).::US9732094, Example 328::US11065253, Example 328	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315904	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315904&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966400	383542574							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616747	Cc1nccnc1C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O2/c1-14-23(30-5-4-29-14)22(25(28)34)17-11-18(20(27)12-19(17)26)24-16-3-2-15(10-21(16)31-13-32-24)33-6-8-35-9-7-33/h2-5,10-13,22H,6-9H2,1H3,(H2,28,34)	GFGSCOPSJYQYMM-UHFFFAOYSA-N	315905	US10172859, Example 329::2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.41 (d, J = 2.6, 1H), 8.39 (d, J = 2.7, 1H), 7.77-7.68 (m, 1H), 7.61 (dd, J = 9.4, 3.1, 1H), 7.59-7.47 (m, 3H), 7.32 (s, 1H), 7.19 (d, J = 2.5, 1H),5.57 (s, 1H), 3.84-3.74 (m, 4H), 3.48-3.41 (m,4H), 2.55 (s, 3H).::US9732094, Example 329::US11065253, Example 329	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315905	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315905&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954863	383542575							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616749	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc(O)c1Cl	InChI=1S/C23H19Cl2N5O3/c24-17-4-1-13(9-16(17)22(31)21-19(25)23(32)29-12-28-21)20-15-3-2-14(10-18(15)26-11-27-20)30-5-7-33-8-6-30/h1-4,9-12,22,31H,5-8H2,(H,28,29,32)	NFMQAKHWNHWLMS-UHFFFAOYSA-N	315906	US10172859, Example 330::5-Chloro-6-{[2- chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrimidin-4-ol1H NMR (500 MHz, DMSO-d6) ppm = 13.06 (s,1H), 9.09 (s, 1H), 8.22-8.14 (m, 2H), 7.97 (d,J = 9.4, 1H), 7.71 (dd, J = 8.2, 2.2, 1H), 7.62-7.56(m, 2H), 7.22 (d, J = 2.6, 1H), 6.46 (d, J = 5.5, 1H),6.31 (d, J = 5.5, 1H), 3.83-3.77 (m, 4H), 3.48-3.43 (m, 4H).::US9732094, Example 330::US11065253, Example 330	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137002407	383542576							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616751	Cc1nccnc1\C(C(O)=O)=C1\C=CC(=O)C(=C1)c1ncnc2cc(ccc12)N1CCOCC1 |c:13,17|	InChI=1S/C25H21N5O4/c1-15-23(27-7-6-26-15)22(25(32)33)16-2-5-21(31)19(12-16)24-18-4-3-17(13-20(18)28-14-29-24)30-8-10-34-11-9-30/h2-7,12-14H,8-11H2,1H3,(H,32,33)	VDDZZCZXKACKKC-UHFFFAOYSA-N	315907	US10172859, Example 331::(3-methyl-pyrazin-2- yl)-[3-(7-morpholin-4- ylquinazolin-4-yl)-4- oxocyclohexa-2,5- dien-(E)-ylidene]- acetic acid1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 8.70 (d, J = 2.5, 1H), 8.56 (d, J = 2.6, 1H), 8.01(dd, J = 8.8, 2.3, 1H), 7.84 (d, J = 2.3, 1H), 7.48 (d,J = 1.4, 2H), 7.38 (d, J = 8.8, 1H), 7.17-7.14 (m,1H), 3.81-3.74 (m, 4H), 3.45-3.39 (m, 4H),2.55 (s, 3H).::US9732094, Example 331::US11065253, Example 331	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315907	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315907&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954825	383542577							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616753	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccsc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(24(32)23-25-16(5-10-34-25)13-29-30-23)11-19(20)22-18-3-2-17(12-21(18)27-14-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	OBVAOTOESQVABX-UHFFFAOYSA-N	315908	US10172859, Example 332::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.56 (s,1H), 9.08 (s, 1H), 8.26 (d, J = 5.4, 1H), 7.79-7.72(m, 2H), 7.70 (d, J = 5.4, 1H), 7.51-7.44 (m, 2H),7.43-7.35 (m, 1H), 7.21-7.16 (m, 1H), 7.10 (d,J = 3.8, 1H), 6.38 (d, J = 3.9, 1H), 3.82-3.74 (m,4H), 3.47-3.40 (m, 4H).::US9732094, Example 332::US11065253, Example 332	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315908&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954809	383542578							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616755	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(25(32)24-18-5-10-34-22(18)13-29-30-24)11-19(20)23-17-3-2-16(12-21(17)27-14-28-23)31-6-8-33-9-7-31/h1-5,10-14,25,32H,6-9H2	AHYKWBDALRQZLR-UHFFFAOYSA-N	315909	US10172859, Example 333::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.84 (d,J = 0.6, 1H), 9.08 (s, 1H), 8.28 (d, J = 5.3, 1H), 7.89(dd, J = 5.4, 0.7, 1H), 7.75-7.67 (m, 2H), 7.49 (dd,J = 9.4, 2.4, 1H), 7.45 (dd, J = 9.4, 2.9, 1H), 7.42-7.34 (m, 1H), 7.19 (d, J = 2.3, 1H), 6.82 (s, 1H),6.42 (s, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).::US9732094, Example 333::US11065253, Example 333	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315909	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315909&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954762	383542579							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616757	Cc1cc(C(C(N)=O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)n(C)c(=O)c1	InChI=1S/C27H25ClFN5O3/c1-15-9-23(33(2)24(35)10-15)25(27(30)36)18-12-19(21(29)13-20(18)28)26-17-4-3-16(11-22(17)31-14-32-26)34-5-7-37-8-6-34/h3-4,9-14,25H,5-8H2,1-2H3,(H2,30,36)	LOAVXRSZRSGZNK-UHFFFAOYSA-N	315910	US10172859, Example 334::2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1,4- dimethyl-6-oxo-1,6- dihydropyridin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.10-7.99 (m, 1H), 7.85 (d, J = 9.4, 1H), 7.58-7.49 (m, 3H), 7.34 (d, J = 7.4, 1H), 7.24-7.17 (m,1H), 6.22-6.15 (m, 1H), 5.79-5.77 (m, 1H),5.47 (s, 1H), 3.82-3.75 (m, 4H), 3.46 (t, J = 5.0,4H), 3.36 (s, 3H), 2.05 (s, 3H).::US9732094, Example 334::US11065253, Example 334	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315910	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315910&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954850	383542580							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616759	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccoc12	InChI=1S/C25H20FN5O3/c26-20-4-1-15(24(32)23-25-16(5-8-34-25)13-29-30-23)11-19(20)22-18-3-2-17(12-21(18)27-14-28-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	PRQMAIDTXMROEL-UHFFFAOYSA-N	315911	US10172859, Example 335::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.59 (s,1H), 9.09 (s, 1H), 8.37 (d, J = 2.1, 1H), 7.82-7.70(m, 2H), 7.54-7.47 (m, 2H), 7.40 (dd, J = 9.8, 8.6,1H), 7.23-7.16 (m, 2H), 6.69 (d, J = 4.6, 1H), 6.40(d, J = 4.6, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).::US9732094, Example 335::US11065253, Example 335	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315911	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315911&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696509	383542581							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616761	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccoc12	InChI=1S/C25H19F2N5O3/c26-19-11-20(27)18(24(33)23-25-14(3-6-35-25)12-30-31-23)10-17(19)22-16-2-1-15(9-21(16)28-13-29-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JFAVIPWOVRTGDI-UHFFFAOYSA-N	315912	US10172859, Example 336::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.63 (s,1H), 9.14 (s, 1H), 8.41 (d, J = 2.1, 1H), 8.10 (t,J = 8.1, 1H), 7.63 (dd, J = 9.4, 3.0, 1H), 7.58 (dd,J = 9.4, 2.5, 1H), 7.45 (t, J = 10.1, 1H), 7.27-7.19(m, 2H), 6.82 (d, J = 5.3, 1H), 6.63 (d, J = 5.3, 1H),3.83-3.77 (m, 4H), 3.50-3.45 (m, 4H).::US9732094, Example 336::US11065253, Example 336	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315912	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315912&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954885	383542582							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616763	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1n[nH]c(=O)c2ccsc12	InChI=1S/C25H20FN5O3S/c26-19-4-1-14(23(32)22-24-17(5-10-35-24)25(33)30-29-22)11-18(19)21-16-3-2-15(12-20(16)27-13-28-21)31-6-8-34-9-7-31/h1-5,10-13,23,32H,6-9H2,(H,30,33)	RBXHRODWJWVHNN-UHFFFAOYSA-N	315913	US10172859, Example 337::7-[[4-Fluoro-3-(7- morpholino- quinazolin-4-yl)- phenyl]hydroxy- methyl]-5H-thieno- [2,3-d}pyridazin-4- one1H NMR (500 MHz, DMSO-d6) ppm = 12.73 (s,1H), 9.10 (s, 1H), 8.04 (d, J = 5.3, 1H), 7.74-7.63(m, 2H), 7.59 (d, J = 5.2, 1H), 7.53-7.45 (m, 2H),7.44-7.37 (m, 1H), 7.23-7.13 (m, 1H), 6.88 (s,1H), 5.94 (s, 1H), 3.82-3.71 (m, 4H), 3.46-3.41(m, 4H).::US9732094, Example 337::US11065253, Example 337	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315913	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315913&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106839	383542583							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616765	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1n[nH]c(=O)c2sccc12	InChI=1S/C25H20FN5O3S/c26-19-4-1-14(23(32)22-17-5-10-35-24(17)25(33)30-29-22)11-18(19)21-16-3-2-15(12-20(16)27-13-28-21)31-6-8-34-9-7-31/h1-5,10-13,23,32H,6-9H2,(H,30,33)	LNISVEWNDLWECN-UHFFFAOYSA-N	315914	US10172859, Example 338::4-[[4-Fluoro-3-(7- morpholino- quinazolin-4-yl)- phenyl]hydroxy- methyl]-6H- thieno[2,3-d}- pyridazin-7-one1H NMR (500 MHz, DMSO-d6) ppm = 12.82 (s,1H), 9.09 (s, 1H), 8.18 (d, J = 5.2, 1H), 7.70-7.64(m, 2H), 7.62 (d, J = 5.2, 1H), 7.50 (dd, J = 9.4, 2.4,1H), 7.47 (dd, J = 9.4, 2.8, 1H), 7.44-7.36 (m, 1H),7.19 (d, J = 2.3, 1H), 6.62 (s, 1H), 6.01 (s, 1H),3.81-3.73 (m, 4H), 3.48-3.40 (m, 4H).::US9732094, Example 338::US11065253, Example 338	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315914	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315914&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106840	383542584							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616767	Cc1cc(C(O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)n(C)c(=O)c1	InChI=1S/C26H24ClFN4O3/c1-15-9-23(31(2)24(33)10-15)26(34)18-12-19(21(28)13-20(18)27)25-17-4-3-16(11-22(17)29-14-30-25)32-5-7-35-8-6-32/h3-4,9-14,26,34H,5-8H2,1-2H3	IASHPBTWDNSSJF-UHFFFAOYSA-N	315915	US10172859, Example 339::6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1,4-dimethyl- 1H-pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s,1H), 7.79 (d, J = 9.5, 1H), 7.71 (d, J = 7.6, 1H), 7.60(dd, J = 9.4, 3.2, 1H), 7.54 (dd, J = 9.4, 2.5, 1H),7.22 (d, J = 2.4, 1H), 6.60 (d, J = 6.2, 1H), 6.27-6.15 (m, 1H), 6.05 (d, J = 6.2, 1H), 5.84-5.68 (m,1H), 3.81-3.75 (m, 4H), 3.52-3.43 (m, 7H),2.05 (s, 3H).::US9732094, Example 339::US11065253, Example 339	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315915	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315915&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954827	383542585							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616769	Cc1cc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)n(C)c(=O)c1	InChI=1S/C26H25FN4O3/c1-16-11-23(30(2)24(32)12-16)26(33)17-3-6-21(27)20(13-17)25-19-5-4-18(14-22(19)28-15-29-25)31-7-9-34-10-8-31/h3-6,11-15,26,33H,7-10H2,1-2H3	DGNYGAHGPZJGOK-UHFFFAOYSA-N	315916	US10172859, Example 340::6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1,4-dimethyl- 1H-pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.62-7.54 (m, 2H), 7.54-7.49 (m, 2H),7.49-7.41 (m, 1H), 7.22-7.18 (m, 1H), 6.50 (d,J = 5.1, 1H), 6.21-6.15 (m, 2H), 5.90 (d, J = 5.1,1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H),3.30 (s, 3H), 2.12 (s, 3H).::US9732094, Example 340::US11065253, Example 340	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315916	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315916&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954842	383542586							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616771	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12	InChI=1S/C25H19F2N5O2S/c26-19-11-20(27)18(25(33)24-16-3-8-35-22(16)12-30-31-24)10-17(19)23-15-2-1-14(9-21(15)28-13-29-23)32-4-6-34-7-5-32/h1-3,8-13,25,33H,4-7H2	CVCJPOLDSCPNQI-UHFFFAOYSA-N	315917	US10172859, Example 341::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.85 (d,J = 0.8, 1H), 9.12 (s, 1H), 8.33 (d, J = 5.3, 1H), 8.01(t, J = 8.1, 1H), 7.91 (dd, J = 5.4, 0.8, 1H), 7.66-7.50 (m, 2H), 7.43 (t, J = 10.1, 1H), 7.21 (d, J = 2.4,1H), 6.84 (s, 1H), 6.63 (s, 1H), 3.86-3.70 (m,4H), 3.54-3.40 (m, 4H).::US9732094, Example 341::US11065253, Example 341	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315917	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315917&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954803	383542587							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616773	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccsc12	InChI=1S/C25H19F2N5O2S/c26-19-11-20(27)18(24(33)23-25-14(3-8-35-25)12-30-31-23)10-17(19)22-16-2-1-15(9-21(16)28-13-29-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	DLKBPTITOLEWFS-UHFFFAOYSA-N	315918	US10172859, Example 342::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.57 (s,1H), 9.09 (s, 1H), 8.27 (d, J = 5.4, 1H), 7.86 (t,J = 8.0, 1H), 7.71 (d, J = 5.4, 1H), 7.61-7.42 (m,3H), 7.19 (d, J = 2.4, 1H), 7.16 (d, J = 4.8, 1H), 6.54(d, J = 4.8, 1H), 3.85-3.69 (m, 4H), 3.50-3.38 (m,4H).::US9732094, Example 342::US11065253, Example 342	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315918	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315918&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954739	383542588							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616775	OC(c1nnc2ccccn12)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21FN6O2/c26-20-7-4-16(24(33)25-30-29-22-3-1-2-8-32(22)25)13-19(20)23-18-6-5-17(14-21(18)27-15-28-23)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	WKLHRHOHIWMJCS-UHFFFAOYSA-N	315919	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol (Ena 2)see racemate::US10172859, Example 344::US10172859, Example 399::US10172859, Example 343::US9732094, Example 399::US11065253, Example 399	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954839	383542589							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616777	OC(c1nnc2ccccn12)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21FN6O2/c26-20-7-4-16(24(33)25-30-29-22-3-1-2-8-32(22)25)13-19(20)23-18-6-5-17(14-21(18)27-15-28-23)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	WKLHRHOHIWMJCS-UHFFFAOYSA-N	315919	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol (Ena 2)see racemate::US10172859, Example 344::US10172859, Example 399::US10172859, Example 343::US9732094, Example 399::US11065253, Example 399	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954839	383542589							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616779	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C25H21FN6O2/c26-20-6-3-16(25(33)24-22-2-1-7-32(22)30-15-29-24)12-19(20)23-18-5-4-17(13-21(18)27-14-28-23)31-8-10-34-11-9-31/h1-7,12-15,25,33H,8-11H2	GHAFGFMIKAKPNE-UHFFFAOYSA-N	315921	US10172859, Example 345::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[2,1-f]- [1,2,4]triazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.49 (s, 1H), 8.08 (dd, J = 2.6, 1.4, 1H), 7.84-7.76 (m, 2H), 7.53-7.45 (m, 2H), 7.42-7.36 (m,1H), 7.29 (dd, J = 4.6, 1.4, 1H), 7.19 (d, J = 2.0, 1H),7.02 (dd, J = 4.6, 2.6, 1H), 6.62 (s, 1H), 6.07 (s,1H), 3.80-3.74 (m, 4H), 3.46-3.41 (m, 4H).::US9732094, Example 345::US11065253, Example 345	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315921	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315921&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954857	383542590							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616781	Cn1cnc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-13-32-23-22(30-12-31-25(23)33)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	YUNSFHVJJPXAJL-UHFFFAOYSA-N	315922	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 421::US10172859, Example 347::US10172859, Example 346::US9732094, Example 421::US11065253, Example 421	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315922	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954880	383542591							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616783	Cn1cnc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-13-32-23-22(30-12-31-25(23)33)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	YUNSFHVJJPXAJL-UHFFFAOYSA-N	315922	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 421::US10172859, Example 347::US10172859, Example 346::US9732094, Example 421::US11065253, Example 421	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315922	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954880	383542591							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616785	NC(=O)C(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncn2cccc12	InChI=1S/C26H21F2N7O2/c27-19-12-20(28)18(11-17(19)23(26(29)36)25-22-2-1-5-35(22)14-32-33-25)24-16-4-3-15(10-21(16)30-13-31-24)34-6-8-37-9-7-34/h1-5,10-14,23H,6-9H2,(H2,29,36)	QFPCISYAPZHVQS-UHFFFAOYSA-N	315924	US10172859, Example 348::2-[2,4-Difluoro-5-(7- morphoin-4-yl- quinazolin-4-yl)- phenyl]-2-pyrrolo- [1,2-a]pyrazin-1-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.23-8.19 (m, 1H), 7.93 (s, 1H), 7.80 (t,J = 8.2, 1H), 7.77 (dd, J = 2.4, 1.4, 1H), 7.63 (dd,J = 9.4, 3.1, 1H), 7.55 (dd, J = 12.3, 2.8, 1H), 7.50(d, J = 10.0, 1H), 7.44 (d, J = 4.8, 1H), 7.33 (s, 1H),7.21 (d, J = 2.5, 1H), 6.94-6.89 (m, 2H), 5.75 (s,1H), 3.82-3.77 (m, 4H), 3.49-3.45 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315924	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315924&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			131997323	383542592							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616787	Cc1nccnc1Cc1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O/c1-16-22(27-7-6-26-16)13-17-2-5-21(25)20(12-17)24-19-4-3-18(14-23(19)28-15-29-24)30-8-10-31-11-9-30/h2-7,12,14-15H,8-11,13H2,1H3	KRHAYZCIDMXCEA-UHFFFAOYSA-N	315925	US10172859, Example 349::4-[2-Fluoro-5-(3- methyl-pyrazin-2- ylmethyl)phenyl]-7- morpholin-4-yl- quinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.43-8.36 (m, 2H), 7.56-7.49 (m, 2H),7.46 (dd, J = 7.8, 5.5, 2H), 7.39-7.33 (m, 1H),7.22-7.16 (m, 1H), 4.28 (s, 2H), 3.81-3.75 (m,4H), 3.46-3.41 (m, 4H), 2.53 (s, 3H).::US9732094, Example 349::US11065253, Example 349	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315925	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315925&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954794	383542593							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616789	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccc2nncn12	InChI=1S/C25H20F2N6O2/c26-19-12-20(27)18(25(34)22-2-1-3-23-31-30-14-33(22)23)11-17(19)24-16-5-4-15(10-21(16)28-13-29-24)32-6-8-35-9-7-32/h1-5,10-14,25,34H,6-9H2	FTUHFJIZLOZDGE-UHFFFAOYSA-N	315926	US10172859, Example 350::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.33 (s,1H), 9.13 (s, 1H), 7.94 (t, J = 8.1, 1H), 7.80 (d,J = 9.2, 1H), 7.61-7.50 (m, 3H), 7.42 (dd, J = 9.26.8, 1H), 7.22 (d, J = 2.4, 1H), 6.93 (d, J = 5.7, 1H),6.87 (d, J = 6.8, 1H), 6.49 (d, J = 5.6, 1H), 3.83-3.75 (m, 4H), 3.49-3.43 (m, 4H).::US9732094, Example 350	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315926	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315926&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954754	383542594							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616791	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cnnc12	InChI=1S/C24H20FN7O2/c25-19-4-1-15(23(33)22-24-30-29-14-32(24)6-5-26-22)11-18(19)21-17-3-2-16(12-20(17)27-13-28-21)31-7-9-34-10-8-31/h1-6,11-14,23,33H,7-10H2	LNWVZTZLLMULBA-UHFFFAOYSA-N	315927	US10172859, Example 351::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]- pyrazin-8-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.44 (s,1H), 9.09 (s, 1H), 8.52 (d, J = 4.7, 1H), 7.91 (d,J = 4.7, 1H), 7.85-7.78 (m, 2H), 7.53 (dd, J = 9.4,2.9, 1H), 7.50 (dd, J = 9.4, 2.4 1H), 7.41-7.35 (m,1H), 7.20 (d, J = 2.3, 1H), 6.51 (s, 1H), 6.43 (s,1H), 3.82-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US9732094, Example 351::US11065253, Example 351	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315927	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315927&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954874	383542595							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616793	COC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C	InChI=1S/C25H24FN5O2/c1-16-23(28-8-7-27-16)25(32-2)17-3-6-21(26)20(13-17)24-19-5-4-18(14-22(19)29-15-30-24)31-9-11-33-12-10-31/h3-8,13-15,25H,9-12H2,1-2H3	VJZQQSPYGNVLNF-UHFFFAOYSA-N	315928	US10172859, Example 353::4-{2-Fluoro-5- [methoxy-(3-methyl- pyrazin-2-yl)methyl]- phenyl}-7-morpholin- 4-ylquinazoline (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.53-8.42 (m, 2H), 7.69-7.58 (m, 2H),7.58-7.48 (m, 2H), 7.48-7.38 (m, 1H), 7.21 (d,J = 1.9, 1H), 5.80 (s, 1H), 3.81-3.70 (m, 4H), 3.48-3.39 (m, 4H), 3.36 (s, 3H), 2.59 (s, 3H).::US10172859, Example 352::US9732094, Example 353::US11065253, Example 353	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315928	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954815	383542596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616795	COC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C	InChI=1S/C25H24FN5O2/c1-16-23(28-8-7-27-16)25(32-2)17-3-6-21(26)20(13-17)24-19-5-4-18(14-22(19)29-15-30-24)31-9-11-33-12-10-31/h3-8,13-15,25H,9-12H2,1-2H3	VJZQQSPYGNVLNF-UHFFFAOYSA-N	315928	US10172859, Example 353::4-{2-Fluoro-5- [methoxy-(3-methyl- pyrazin-2-yl)methyl]- phenyl}-7-morpholin- 4-ylquinazoline (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.53-8.42 (m, 2H), 7.69-7.58 (m, 2H),7.58-7.48 (m, 2H), 7.48-7.38 (m, 1H), 7.21 (d,J = 1.9, 1H), 5.80 (s, 1H), 3.81-3.70 (m, 4H), 3.48-3.39 (m, 4H), 3.36 (s, 3H), 2.59 (s, 3H).::US10172859, Example 352::US9732094, Example 353::US11065253, Example 353	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315928	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954815	383542596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616797	Cc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C25H24FN5O2/c1-15-13-27-23(16(2)30-15)25(32)17-3-6-21(26)20(11-17)24-19-5-4-18(12-22(19)28-14-29-24)31-7-9-33-10-8-31/h3-6,11-14,25,32H,7-10H2,1-2H3	PCLBXBKEXTTXEW-UHFFFAOYSA-N	315930	US10172859, Example 354::(3,5-Dimethyl- pyrazin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.30 (s, 1H), 7.60-7.50 (m, 4H), 7.41-7.33(m, 1H), 7.23-7.17 (m, 1H), 6.20 (d, J = 5.4, 1H),6.04 (d, J = 5.2, 1H), 3.81-3.76 (m, 4H), 3.47-3.42 (m, 4H), 2.50 (s, 3H), 2.43 (s, 3H).::US9732094, Example 354::US11065253, Example 354	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315930	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315930&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954915	383542597							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616799	Cc1cnc(C(O)c2cc(c(F)cc2F)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C25H23F2N5O2/c1-14-12-28-23(15(2)31-14)25(33)19-10-18(20(26)11-21(19)27)24-17-4-3-16(9-22(17)29-13-30-24)32-5-7-34-8-6-32/h3-4,9-13,25,33H,5-8H2,1-2H3	IPICVMLCQXXLCH-UHFFFAOYSA-N	315931	US10172859, Example 355::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3,5- dimethyl-pyrazin-2- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 8.26 (s, 1H), 7.89 (t, J = 8.2, 1H), 7.61 (dd,J = 9.4, 3.2, 1H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.39 (t,J = 10.1, 1H), 7.21 (d, J = 2.4, 1H), 6.28 (d, J = 6.0,1H), 6.23 (d, J = 6.0, 1H), 3.82-3.75 (m, 4H), 3.49-3.41 (m, 4H), 2.62 (s, 3H), 2.43 (s, 3H).::US9732094, Example 355::US11065253, Example 355	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315931	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315931&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954871	383542598							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616801	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H22FN5O2/c27-21-6-3-17(26(33)25-23-2-1-8-32(23)9-7-28-25)14-20(21)24-19-5-4-18(15-22(19)29-16-30-24)31-10-12-34-13-11-31/h1-9,14-16,26,33H,10-13H2	KEDFGJHVFDJAQW-UHFFFAOYSA-N	315932	US10172859, Example 356::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.20 (dd, J = 4.8, 1.0, 1H), 7.79-7.72 (m, 3H),7.53-7.45 (m, 3H), 7.40-7.34 (m, 1H), 7.20 (d,J = 2.1, 1H), 7.02 (dt, J = 4.1, 1.2, 1H), 6.87 (dd,J = 4.1, 2.5, 1H), 6.33 (d, J = 4.9, 1H), 6.06 (d,J = 4.8, 1H), 3.82-3.76 (m, 4H), 3.48-3.42 (m,4H).::US9732094, Example 356::US11065253, Example 356	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315932	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315932&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954956	383542599							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616803	COc1ccc(nn1)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	VIBCJCNFUWTJBS-UHFFFAOYSA-N	315933	US10172859, Example 357::[2-Fluoro-4-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.00 (d, J = 7.1, 2.3, 1H), 7.89 (d, J = 9.4, 1H),7.80-7.71 (m, 2H), 7.55 (dd, J = 9.5, 2.6, 1H),7.38 (dd, J = 10.0, 8.4, 1H), 7.27-7.18 (m, 2H),6.57 (d, J = 4.8, 1H), 6.24 (d, J = 4.8, 1H), 4.01 (s,3H), 3.85-3.71 (m, 4H), 3.51-3.40 (m, 4H).::US9732094, Example 357::US11065253, Example 357	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315933	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315933&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954965	383542600							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616805	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H21F2N5O2/c27-20-14-21(28)19(26(34)25-23-2-1-6-33(23)7-5-29-25)13-18(20)24-17-4-3-16(12-22(17)30-15-31-24)32-8-10-35-11-9-32/h1-7,12-15,26,34H,8-11H2	WWULIMQUQVVHHC-UHFFFAOYSA-N	315934	US10172859, Example 358::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a] pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 8.25-8.19 (m, 1H), 7.94 (t, J = 8.2, 1H), 7.78(dd, J = 2.5, 1.3, 1H), 7.58 (dd, J = 9.3, 3.0, 1H),7.55 (dd, J = 9.4, 2.4, 1H), 7.47-7.39 (m, 2H),7.22 (d, J = 2.3, 1H), 6.97-6.93 (m, 1H), 6.91 (dd,J = 4.1, 2.5, 1H), 6.43 (d, J = 5.9, 1H), 6.30 (d,J = 5.9, 1H), 3.82-3.76 (m, 4H), 3.49-3.44 (m,4H).::US9732094, Example 358::US11065253, Example 358	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315934	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315934&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954760	383542601							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616807	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H21ClFN5O2/c27-20-14-21(28)19(13-18(20)26(34)25-23-2-1-6-33(23)7-5-29-25)24-17-4-3-16(12-22(17)30-15-31-24)32-8-10-35-11-9-32/h1-7,12-15,26,34H,8-11H2	OWORGYHATQJZBK-UHFFFAOYSA-N	315935	US10172859, Example 359::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 8.20 (dd, J = 4.7, 1.0, 1H), 7.97 (d, J = 7.8, 1H),7.76 (dd, J = 2.5, 1.3, 1H), 7.63 (d, J = 9.5, 1H), 7.60(dd, J = 9.4, 3.2, 1H), 7.55 (dd, J = 9.4, 2.6, 1H),7.40 (d, J = 4.8, 1H), 7.21 (d, J = 2.5, 1H), 7.00-6.95 (m, 1H), 6.91 (dd, J = 4.1, 2.5, 1H), 6.48 (d,J = 6.2, 1H), 6.36 (d, J = 6.1, 1H), 3.81-3.75 (m,4H), 3.48-3.43 (m, 4H).::US9732094, Example 359::US11065253, Example 359	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315935	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315935&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954837	383542602							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616809	Cn1c(nccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-29-21(31)6-7-26-24(29)23(32)15-2-5-19(25)18(12-15)22-17-4-3-16(13-20(17)27-14-28-22)30-8-10-33-11-9-30/h2-7,12-14,23,32H,8-11H2,1H3	VRBINPYXVFOIEZ-UHFFFAOYSA-N	315936	US10172859, Example 360::2-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-3-methyl-3H- pyrimidin-4-one1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.91 (d, J = 6.5, 1H), 7.67-7.60 (m, 2H), 7.60-7.50 (m, 2H), 7.44 (t, J = 9.5, 1H), 7.20 (d, J = 1.7,1H), 6.72 (s, 1H), 6.38 (d, J = 6.5, 1H), 6.00 (s,1H), 3.82-3.73 (m, 4H), 3.48 (s, 3H), 3.47-3.42(m, 4H).::US9732094, Example 360::US11065253, Example 360	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315936	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315936&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954770	383542603							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616811	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H22ClN5O2/c27-21-6-3-17(14-20(21)26(33)25-23-2-1-8-32(23)9-7-28-25)24-19-5-4-18(15-22(19)29-16-30-24)31-10-12-34-13-11-31/h1-9,14-16,26,33H,10-13H2	MAVRQQXHKQFAMV-UHFFFAOYSA-N	315937	US10172859, Example 361::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.22-8.19 (m, 1H), 8.14 (d, J = 2.2, 1H), 7.89(d, J = 9.4, 1H), 7.76 (dd, J = 2.5, 1.3, 1H), 7.70 (dd,J = 8.2, 2.2, 1H), 7.61 (d, J = 8.2, 1H), 7.53 (dd,J = 9.5, 2.6, 1H). 7.43 (d, J = 4.8, 1H), 7.21 (d,J = 2.6, 1H), 7.00-6.97 (m, 1H), 6.93-6.90 (m,1H), 6.45-6.40 (m, 2H), 3.81-3.76 (m, 4H),3.48-3.42 (m, 4H).::US9732094, Example 361::US11065253, Example 361	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315937	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315937&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954797	383542604							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616813	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C25H21ClN6O2/c26-20-6-3-16(12-19(20)25(33)24-22-2-1-7-32(22)30-15-29-24)23-18-5-4-17(13-21(18)27-14-28-23)31-8-10-34-11-9-31/h1-7,12-15,25,33H,8-11H2	VHMBWFZHXLMGJM-UHFFFAOYSA-N	315938	US10172859, Example 362::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[2,1-f]- [1,2,4]triazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.49 (s, 1H), 8.16 (d, J = 2.2, 1H), 8.12 (dd,J = 2.6, 1.4, 1H), 7.88 (d, J = 9.4, 1H), 7.74 (dd,J = 8.2, 2.2, 1H), 7.64 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.23-7.19 (m, 2H), 7.06 (dd,J = 4.6, 2.6, 1H), 6.80 (d, J = 5.7, 1H), 6.44 (d,J = 5.7, 1H), 3.81-3.76 (m, 4H), 3.48-3.43 (m,4H).::US9732094, Example 362::US11065253, Example 362	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315938	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315938&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954877	383542605							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616815	Cn1c(cccc1=O)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	NGKARPNDTRDPQL-UHFFFAOYSA-N	315939	US10172859, Example 364::US10172859, Example 400::6-{[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 363::US9732094, Example 400::US11065253, Example 400	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954744	383542606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616817	Cn1c(cccc1=O)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	NGKARPNDTRDPQL-UHFFFAOYSA-N	315939	US10172859, Example 364::US10172859, Example 400::6-{[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 363::US9732094, Example 400::US11065253, Example 400	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954744	383542606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616819	Cn1c(cccc1=O)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	PKBPQGNBNQFAKJ-UHFFFAOYSA-N	315941	6-{[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 366::US10172859, Example 401::US10172859, Example 365::US9732094, Example 401::US11065253, Example 401	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954788	383542607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616821	Cn1c(cccc1=O)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	PKBPQGNBNQFAKJ-UHFFFAOYSA-N	315941	6-{[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 366::US10172859, Example 401::US10172859, Example 365::US9732094, Example 401::US11065253, Example 401	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954788	383542607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616823	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(=O)[nH]n1	InChI=1S/C23H20FN5O3/c24-18-4-1-14(23(31)19-5-6-21(30)28-27-19)11-17(18)22-16-3-2-15(12-20(16)25-13-26-22)29-7-9-32-10-8-29/h1-6,11-13,23,31H,7-10H2,(H,28,30)	LILWOSWCHKKJRS-UHFFFAOYSA-N	315651	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2H- pyridazin-3-one (Ena 2)1H NMR (400 MHz, DMSO-d6) ppm = 12.86 (s, 1H), 9.10 (s, 1H), 7.64-7.58 (m, 2H), 7.55-7.50 (m, 2H), 7.48 (d, J = 9.8, 1H), 7.45-7.38 (m, 1H), 7.23-7.16 (m, 1H), 6.87 (d, J = 9.8, 1H), 6.44 (d, J = 4.3, 1H), 5.70-5.62 (m, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 367::US10172859, Example 76::US9732094, Example 76::US11065253, Example 76	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315651&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106837	383542390							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616825	Cn1c(nccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-21(32)4-5-27-24(30)23(33)16-11-17(19(26)12-18(16)25)22-15-3-2-14(10-20(15)28-13-29-22)31-6-8-34-9-7-31/h2-5,10-13,23,33H,6-9H2,1H3	SVHBTMUPWLWKHQ-UHFFFAOYSA-N	315944	US10172859, Example 368::2-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-3-methyl-3H- pyrimidin-4-one1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 7.88 (d, J = 7.7, 1H), 7.83 (d, J = 6.5, 1H), 7.70(d, J = 9.4, 1H), 7.63 (dd, J = 9.4, 3.2, 1H), 7.57 (dd,J = 9.5, 2.5, 1H), 7.23 (d, J = 2.4, 1H), 6.91 (d,J = 7.0, 1H), 6.39 (d, J = 6.5, 1H), 6.15 (d, J = 7.0,1H), 3.83-3.76 (m, 4H), 3.72 (s, 3H), 3.50-3.44(m, 4H).::US9732094, Example 368::US11065253, Example 368	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315944	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315944&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954793	383542608							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616827	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H21ClN6O2/c26-20-4-1-16(13-19(20)24(33)23-25-28-6-8-32(25)7-5-27-23)22-18-3-2-17(14-21(18)29-15-30-22)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	STWNBZFJDDCWDB-UHFFFAOYSA-N	315945	US10172859, Example 369::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.57 (d, J = 4.5, 1H), 8.27 (d, J = 2.2, 1H), 8.18(d, J = 1.1, 1H), 8.04 (d, J = 9.4, 1H), 7.88 (d, J = 1.1,1H), 7.83 (d, J = 4.5, 1H), 7.72 (dd, J = 8.2, 2.3, 1H),7.62-7.55 (m, 2H), 7.23 (d, J = 2.6, 1H), 6.87 (d,J = 5.8, 1H), 6.50 (d, J = 5.9, 1H), 3.83-3.78 (m,4H), 3.50-3.45 (m, 4H).::US9732094, Example 369::US11065253, Example 369	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315945	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315945&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954933	383542609							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616829	Cn1cnc2c(ncnc12)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-14-31-23-22(29-13-30-25(23)32)24(34)18-10-15(2-5-19(18)26)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	TVNNXSNDWDOGSD-UHFFFAOYSA-N	315946	US10172859, Example 370::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.91 (s, 1H), 8.58 (s, 1H), 8.28 (dd, J = 7.0,2.3, 1H), 8.05 (d, J = 9.4, 1H), 7.72 (ddd, J = 8.3,5.0, 2.4, 1H), 7.58 (dd, J = 9.5, 2.6, 1H), 7.30 (dd,J = 10.0, 8.5, 1H), 7.21 (d, J = 2.5, 1H), 6.66 (d,J = 5.5, 1H), 6.44 (d, J = 5.6, 1H), 3.85 (s, 3H), 3.82-3.78 (m, 4H), 3.49-3.45 (m, 4H).::US9732094, Example 370::US11065253, Example 370	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315946	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315946&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954833	383542610							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616831	Cn1cnc2c(ncnc12)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClN7O2/c1-32-14-31-23-22(29-13-30-25(23)32)24(34)18-10-15(2-5-19(18)26)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	SLTAVZNCQZTPAE-UHFFFAOYSA-N	315947	US10172859, Example 371::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.90 (s, 1H), 8.59 (s, 1H), 8.38 (d, J = 2.2,1H), 8.12 (d, J = 9.4, 1H), 7.70 (dd, J = 8.8, 2.3, 1H),7.60 (dd, J = 9.5, 2.6, 1H), 7.56 (d, J = 8.2, 1H), 7.23(d, J = 2.6, 1H), 6.71 (d, J = 5.4, 1H), 6.53 (d, J = 5.4,1H), 3.86 (s, 3H), 3.82-3.77 (m, 4H), 3.49-3.45(m, 4H).::US9732094, Example 371::US11065253, Example 371	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315947	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315947&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954955	383542611							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616833	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H21FN6O2/c26-20-4-1-16(13-19(20)24(33)23-25-28-6-8-32(25)7-5-27-23)22-18-3-2-17(14-21(18)29-15-30-22)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	SQAFIECUCNRFEB-UHFFFAOYSA-N	315948	US10172859, Example 372::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.58 (d, J = 4.5, 1H), 8.24-8.16 (m, 2H), 8.00(d, J = 9.4, 1H), 7.91-7.83 (m, 2H), 7.74 (ddd,J = 8.1, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6, 1H),7.33 (dd, J = 10.0, 8.5, 1H), 7.22 (d, J = 2.5, 1H),6.80 (d, J = 5.9, 1H), 6.39 (d, J = 6.0, 1H), 3.86-3.75 (m, 4H), 3.52-3.43 (m, 4H).::US9732094, Example 372::US11065253, Example 372	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315948	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315948&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954912	383542612							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616835	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccc2nncn12	InChI=1S/C25H21FN6O2/c26-20-7-4-16(12-19(20)25(33)22-2-1-3-23-30-29-15-32(22)23)24-18-6-5-17(13-21(18)27-14-28-24)31-8-10-34-11-9-31/h1-7,12-15,25,33H,8-11H2	GEQVWQSNVNSBLE-UHFFFAOYSA-N	315949	US10172859, Example 373::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.36-9.30(m, 1H), 9.07 (s, 1H), 8.03 (dd, J = 7.2, 2.3, 1H),7.86-7.76 (m, 3H), 7.52-7.38 (m, 3H), 7.21 (d,J = 2.6, 1H), 6.91 (d, J = 5.6, 1H), 6.87-6.80 (m,1H), 6.53 (d, J = 5.6, 1H), 3.83-3.74 (m, 4H), 3.48-3.40 (m, 4H).::US9732094, Example 373::US11065253, Example 373	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315949	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315949&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954924	383542613							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616837	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	AYUGGJOQLWWJHH-UHFFFAOYSA-N	315950	US10172859, Example 374::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 9.02 (s, 1H), 8.59 (d, J = 2.2, 1H), 8.20 (dd,J = 7.0, 2.3, 1H), 7.92 (d, J = 9.4, 1H), 7.77 (ddd,J = 8.4, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6, 1H),7.37 (dd, J = 10.0, 8.5, 1H), 7.27 (d, J = 2.3, 1H),7.22 (d, J = 2.5, 1H), 6.73 (d, J = 5.2, 1H), 6.48 (d,J = 5.1, 1H), 3.82-3.76 (m, 4H), 3.49-3.44 (m,4H).::US9732094, Example 374::US11065253, Example 374	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315950	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315950&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954748	383542614							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616839	Cn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)16-5-8-20(26)19(13-16)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	IVAQITIIINVXDO-UHFFFAOYSA-N	315666	US10172859, Example 375::6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.60-7.56 (m, 2H), 7.55-7.51 (m, 2H), 7.48- 7.43 (m, 1H), 7.40 (dd, J = 9.1, 6.9, 1H), 7.21-7.19 (m, 1H), 6.52 (d, J = 5.3, 1H), 6.36 (dd, J = 9.1, 1.4, 1H), 6.25 (dd, J = 7.0, 1.4, 1H), 5.94 (d, J = 5.1, 1H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.38 (s, 3H).::US10172859, Example 376::US10172859, Example 91::US9732094, Example 91::US11065253, Example 91	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315666&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292653	383542404							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616841	Cn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)16-5-8-20(26)19(13-16)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	IVAQITIIINVXDO-UHFFFAOYSA-N	315666	US10172859, Example 375::6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.60-7.56 (m, 2H), 7.55-7.51 (m, 2H), 7.48- 7.43 (m, 1H), 7.40 (dd, J = 9.1, 6.9, 1H), 7.21-7.19 (m, 1H), 6.52 (d, J = 5.3, 1H), 6.36 (dd, J = 9.1, 1.4, 1H), 6.25 (dd, J = 7.0, 1.4, 1H), 5.94 (d, J = 5.1, 1H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.38 (s, 3H).::US10172859, Example 376::US10172859, Example 91::US9732094, Example 91::US11065253, Example 91	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315666	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315666&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292653	383542404							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616843	Cc1cncnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-12-28-13-30-23(15)22(25(27)33)19-10-16(2-5-20(19)26)24-18-4-3-17(11-21(18)29-14-31-24)32-6-8-34-9-7-32/h2-5,10-14,22H,6-9H2,1H3,(H2,27,33)	XNDMXGNHPWCDKX-UHFFFAOYSA-N	315953	US10172859, Example 378::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(5-methyl- pyrimidin-4-yl)- acetamide (Ena 2)see racemate::US10172859, Example 407::US10172859, Example 377::US9732094, Example 407::US11065253, Example 407	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954832	383542615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616845	Cc1cncnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-12-28-13-30-23(15)22(25(27)33)19-10-16(2-5-20(19)26)24-18-4-3-17(11-21(18)29-14-31-24)32-6-8-34-9-7-32/h2-5,10-14,22H,6-9H2,1H3,(H2,27,33)	XNDMXGNHPWCDKX-UHFFFAOYSA-N	315953	US10172859, Example 378::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(5-methyl- pyrimidin-4-yl)- acetamide (Ena 2)see racemate::US10172859, Example 407::US10172859, Example 377::US9732094, Example 407::US11065253, Example 407	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954832	383542615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616847	OC(c1nnc2ccccn12)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(24(34)25-31-30-22-3-1-2-6-33(22)25)12-17(19)23-16-5-4-15(11-21(16)28-14-29-23)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	KVBITJQMDOZXFN-UHFFFAOYSA-N	315956	US10172859, Example 379::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 8.63 (dt, J = 7.1, 1.2, 1H), 8.02 (t, J = 8.1, 1H),7.81 (dt, J = 9.3, 1.1, 1H), 7.64 (dd, J = 9.4, 3.3, 1H),7.60-7.50 (m, 2H), 7.44 (ddd, J = 9.3, 6.6, 1.1,1H), 7.23 (d, J = 2.5, 1H), 7.06 (td, J = 6.8, 1.0, 1H),6.87 (d, J = 6.0, 1H), 6.69 (d, J = 6.0, 1H), 3.82-3.77 (m, 4H), 3.49-3.45 (m, 4H).::US9732094, Example 379::US11065253, Example 379	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315956	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315956&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954740	383542617							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616849	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-30-22(3-2-4-23(30)32)25(33)18-12-17(19(26)13-20(18)27)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	TYEQLJVPHLCAPI-UHFFFAOYSA-N	315957	US10172859, Example 436::6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 381::US10172859, Example 380::US9732094, Example 436::US11065253, Example 436	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954779	383542618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616851	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-30-22(3-2-4-23(30)32)25(33)18-12-17(19(26)13-20(18)27)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	TYEQLJVPHLCAPI-UHFFFAOYSA-N	315957	US10172859, Example 436::6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 381::US10172859, Example 380::US9732094, Example 436::US11065253, Example 436	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954779	383542618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616853	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-30-22(3-2-4-23(30)32)25(33)17-12-18(20(27)13-19(17)26)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	WYNSFINJUTXESJ-UHFFFAOYSA-N	315959	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 435::US10172859, Example 383::US10172859, Example 382::US9732094, Example 435::US11065253, Example 435	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696425	383542619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616855	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-30-22(3-2-4-23(30)32)25(33)17-12-18(20(27)13-19(17)26)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	WYNSFINJUTXESJ-UHFFFAOYSA-N	315959	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 435::US10172859, Example 383::US10172859, Example 382::US9732094, Example 435::US11065253, Example 435	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696425	383542619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616857	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3F)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21F2N7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	VGKMJMNCNMRSEO-UHFFFAOYSA-N	315961	US10172859, Example 386::US10172859, Example 431::(R)-[2,4-Difluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 384::US9732094, Example 431::US11065253, Example 431	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954829	383542620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616859	Cn1ncc2c(ncnc12)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClN7O2/c1-32-25-19(12-31-32)23(29-14-30-25)24(34)18-10-15(2-5-20(18)26)22-17-4-3-16(11-21(17)27-13-28-22)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	BSOZSTWDPAKLPX-UHFFFAOYSA-N	315962	US10172859, Example 385::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.92 (s, 1H), 8.44 (s, 1H), 7.95 (d, J = 2.2,1H), 7.80 (d, J = 9.4, 1H), 7.72 (dd, J = 8.2, 2.2, 1H),7.66 (d, J = 8.2, 1H), 7.50 (dd, J = 9.5, 2.6, 1H), 7.19(d, J = 2.5, 1H), 6.90 (d, J = 4.9, 1H), 6.49 (d, J = 4.9,1H), 4.05 (s, 3H), 3.82-3.76 (m, 4H), 3.47-3.41(m, 4H).::US9732094, Example 385	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315962	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315962&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954866	383542621							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616861	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3F)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21F2N7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	VGKMJMNCNMRSEO-UHFFFAOYSA-N	315961	US10172859, Example 386::US10172859, Example 431::(R)-[2,4-Difluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 384::US9732094, Example 431::US11065253, Example 431	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954829	383542620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616863	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2CNCCc12	InChI=1S/C26H24F2N6O2/c27-20-11-21(28)19(26(35)25-17-3-4-29-12-23(17)31-14-33-25)10-18(20)24-16-2-1-15(9-22(16)30-13-32-24)34-5-7-36-8-6-34/h1-2,9-11,13-14,26,29,35H,3-8,12H2	DGNNVCHHZJSLTB-UHFFFAOYSA-N	315964	US10172859, Example 387::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5,6,7,8- tetrahydropyrido- [3,4-d}pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.83 (s, 1H), 7.87 (t, J = 8.2, 1H), 7.60 (dd,J = 9.4, 3.0, 1H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.42 (t,J = 10.1, 1H), 7.21 (d, J = 2.4, 1H), 6.33 (d, J = 6.3,1H), 6.16 (d, J = 6.3, 1H), 3.86 (s, 2H), 3.82-3.75(m, 4H), 3.49-3.42 (m, 4H), 3.09-2.94 (m, 2H),2.94-2.72 (m, 2H).::US9732094, Example 387	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315964&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954790	383542622							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616865	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2CNCCc12	InChI=1S/C26H25FN6O2/c27-21-4-1-16(26(34)25-19-5-6-28-13-23(19)30-15-32-25)11-20(21)24-18-3-2-17(12-22(18)29-14-31-24)33-7-9-35-10-8-33/h1-4,11-12,14-15,26,28,34H,5-10,13H2	CCPJVMRJOCCOET-UHFFFAOYSA-N	315965	US10172859, Example 388::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5,6,7,8- tetrahydropyrido- [3,4-d}pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.88 (s, 1H), 7.64-7.56 (m, 2H), 7.55-7.50(m, 2H), 7.38 (dd, J = 10.5, 8.1, 1H), 7.23-7.16(m, 1H), 6.20 (d, J = 5.8, 1H), 5.96 (d, J = 5.8, 1H),3.83 (s, 2H), 3.81-3.72 (m, 4H), 3.49-3.39 (m,4H), 3.05-2.84 (m, 2H), 2.77-2.72 (m, 2H).::US9732094, Example 388	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315965&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966402	383542623							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616867	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncncc1F	InChI=1S/C23H19ClFN5O2/c24-18-4-1-14(9-17(18)23(31)22-19(25)11-26-12-28-22)21-16-3-2-15(10-20(16)27-13-29-21)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	LGZAMQCFFYGHBM-UHFFFAOYSA-N	315966	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-fluoro- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 412::US10172859, Example 390::US10172859, Example 389::US9732094, Example 412::US11065253, Example 412	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954820	383542624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616869	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncncc1F	InChI=1S/C23H19ClFN5O2/c24-18-4-1-14(9-17(18)23(31)22-19(25)11-26-12-28-22)21-16-3-2-15(10-20(16)27-13-29-21)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	LGZAMQCFFYGHBM-UHFFFAOYSA-N	315966	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-fluoro- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 412::US10172859, Example 390::US10172859, Example 389::US9732094, Example 412::US11065253, Example 412	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954820	383542624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616871	Cn1ncc2c(ncnc12)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-25-19(12-31-32)23(29-14-30-25)24(34)18-10-15(2-5-20(18)26)22-17-4-3-16(11-21(17)27-13-28-22)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	HTZLXCWYVJYAAH-UHFFFAOYSA-N	315968	US10172859, Example 391::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.90 (s, 1H), 8.49 (s, 1H), 7.93 (dd, J = 6.9,2.3, 1H), 7.81 (d, J = 9.4, 1H), 7.74 (ddd, J = 8.4,4.9, 2.3, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.40 (dd,J = 9.9, 8.5, 1H), 7.19 (d, J = 2.6, 1H), 6.88 (s, 1H),6.37 (s, 1H), 4.05 (s, 3H), 3.81-3.75 (m, 4H),3.51-3.42 (m, 4H).::US9732094, Example 391::US11065253, Example 391	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954845	383542625							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616873	Cc1cncnc1C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	JJQXPFGHPBRZAM-UHFFFAOYSA-N	315969	US10172859, Example 392::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.98 (s, 1H), 8.64 (s, 1H), 8.07 (dd, J = 7.1,2.3, 1H), 7.93 (d, J = 9.4, 1H), 7.74 (ddd, J = 8.3,5.0, 2.3, 1H), 7.57 (dd, J = 9.5, 2.6 1H), 7.35 (dd,J = 10.1, 8.4, 1H), 7.21 (d, J = 2.6, 1H), 6.38 (d,J = 6.0 1H), 6.25 (d, J = 6.0, 1H), 3.82-3.76 (m,4H), 3.51-3.43 (m, 4H), 2.41 (s, 3H).::US9732094, Example 392::US11065253, Example 392	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315969	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315969&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955005	383542626							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616875	Cc1nccnc1C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QBVSEWPWWHRRDD-UHFFFAOYSA-N	315970	US10172859, Example 393::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.45 (d, J = 2.5, 1H), 8.41 (d, J = 2.5, 1H), 8.09(dd, J = 7.1, 2.3, 1H), 7.94 (d, J = 9.4, 1H), 7.74(ddd, J = 7.9, 5.0, 2.3, 1H), 7.56 (dd, J = 9.5, 2.6,1H), 7.33 (dd, J = 10.1, 8.4, 1H), 7.21 (d, J = 2.5,1H), 6.35 (d, J = 5.8, 1H), 6.32 (d, J = 5.9, 1H), 3.83-3.76 (m, 4H), 3.45 (t, J = 4.9, 4H), 2.68 (s, 3H).::US9732094, Example 393::US11065253, Example 393	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315970&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954934	383542627							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616877	COc1nccnc1C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QDHRMZSLIZGZJU-UHFFFAOYSA-N	315971	US10172859, Example 394::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.19 (d, J = 2.7, 1H), 8.17 (d, J = 2.7, 1H), 8.07(dd, J = 8.3, 1H), 7.93 (d, J = 9.4, 1H), 7.73(ddd, J = 8.3, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6,1H), 7.33 (dd, J = 10.1, 8.4, 1H), 7.22 (d, J = 2.5,1H), 6.35 (d, J = 6.0, 1H), 6.21 (d, J = 6.0, 1H), 3.98(s, 3H), 3.82-3.76 (m, 4H), 3.46 (dd, J = 5.9, 3.9,4H).::US9732094, Example 394::US11065253, Example 394	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315971&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954851	383542628							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616879	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)24(34)23-25-29-4-6-33(25)5-3-28-23)22-16-2-1-15(11-21(16)30-14-31-22)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	SRSGLQYXZLUTFB-UHFFFAOYSA-N	315972	US10172859, Example 396::US10172859, Example 397::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol (Ena 2)see racemate::US10172859, Example 395::US9732094, Example 397::US11065253, Example 397	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954861	383542629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616881	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)24(34)23-25-29-4-6-33(25)5-3-28-23)22-16-2-1-15(11-21(16)30-14-31-22)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	SRSGLQYXZLUTFB-UHFFFAOYSA-N	315972	US10172859, Example 396::US10172859, Example 397::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol (Ena 2)see racemate::US10172859, Example 395::US9732094, Example 397::US11065253, Example 397	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954861	383542629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616883	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)24(34)23-25-29-4-6-33(25)5-3-28-23)22-16-2-1-15(11-21(16)30-14-31-22)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	SRSGLQYXZLUTFB-UHFFFAOYSA-N	315972	US10172859, Example 396::US10172859, Example 397::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol (Ena 2)see racemate::US10172859, Example 395::US9732094, Example 397::US11065253, Example 397	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954861	383542629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616885	CCn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H25FN4O3/c1-2-31-23(4-3-5-24(31)32)26(33)17-6-9-21(27)20(14-17)25-19-8-7-18(15-22(19)28-16-29-25)30-10-12-34-13-11-30/h3-9,14-16,26,33H,2,10-13H2,1H3	HPNZHZQMNZAMPI-UHFFFAOYSA-N	315975	US10172859, Example 398::1-Ethyl-6-{[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1H-pyridin-2- one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.63-7.56 (m, 2H), 7.54 (dd, J = 9.4, 2.5, 1H),7.52-7.43 (m, 2H), 7.41 (dd, J = 9.1, 6.9, 1H),7.20 (d, J = 2.4, 1H), 6.58 (d, J = 1H), 6.35 (dd,J = 9.1, 1.4, 1H), 6.31 (dd, J = 7.1, 1.4, 1H), 5.91 (d,J = 5.0, 1H), 4.05-3.88 (m, 2H), 3.81-3.74 (m,4H), 3.48-3.39 (m, 4H), 0.95 (t, J = 6.9, 3H).::US9732094, Example 398::US11065253, Example 398	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315975	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315975&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966403	383542630							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616887	OC(c1nnc2ccccn12)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21FN6O2/c26-20-7-4-16(24(33)25-30-29-22-3-1-2-8-32(22)25)13-19(20)23-18-6-5-17(14-21(18)27-15-28-23)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	WKLHRHOHIWMJCS-UHFFFAOYSA-N	315919	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol (Ena 2)see racemate::US10172859, Example 344::US10172859, Example 399::US10172859, Example 343::US9732094, Example 399::US11065253, Example 399	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315919	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954839	383542589							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616889	Cn1c(cccc1=O)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	NGKARPNDTRDPQL-UHFFFAOYSA-N	315939	US10172859, Example 364::US10172859, Example 400::6-{[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 363::US9732094, Example 400::US11065253, Example 400	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315939	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954744	383542606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616891	Cn1c(cccc1=O)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	PKBPQGNBNQFAKJ-UHFFFAOYSA-N	315941	6-{[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 366::US10172859, Example 401::US10172859, Example 365::US9732094, Example 401::US11065253, Example 401	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315941	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954788	383542607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616893	Cn1ncc2c(ncnc12)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN7O2/c1-33-25-18(11-32-33)23(30-13-31-25)24(35)16-9-17(20(27)10-19(16)26)22-15-3-2-14(8-21(15)28-12-29-22)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	BQKWVPQKBYQALO-UHFFFAOYSA-N	315979	US10172859, Example 402::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d]- pyrimdiin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.90 (s, 1H), 8.44 (s, 1H), 7.81 (d, J = 7.6,1H), 7.69 (d, J = 9.5, 1H), 7.56-7.48 (m, 2H), 7.22-7.16 (m, 1H), 6.92 (d, J = 5.0, 1H), 6.43 (d, J = 5.0,1H), 4.04 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.40(m, 4H).::US9732094, Example 402::US11065253, Example 402	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315979	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315979&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954753	383542631							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616895	Cn1ncc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-25-18(11-32-33)23(30-13-31-25)24(35)17-9-16(19(26)10-20(17)27)22-15-3-2-14(8-21(15)28-12-29-22)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	IGGXDPOYOQKHHJ-UHFFFAOYSA-N	315980	US10172859, Example 403::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.89 (s, 1H), 8.49 (s, 1H), 7.79 (t, J = 8.0,1H), 7.56-7.50 (m, 2H), 7.47 (t, J = 10.0, 1H),7.19 (s, 1H), 6.88 (s, 1H), 6.32 (s, 1H), 4.04 (s,3H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H).::US9732094, Example 403::US11065253, Example 403	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315980	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315980&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954928	383542632							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616897	Cn1ncc2c(ncnc12)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-25-19(12-31-32)23(29-14-30-25)24(34)15-2-5-20(26)18(10-15)22-17-4-3-16(11-21(17)27-13-28-22)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	HPWPZDRXPQVODT-UHFFFAOYSA-N	315981	US10172859, Example 404::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.91 (s, 1H), 8.53 (s, 1H), 7.79-7.72 (m,2H), 7.54-7.44 (m, 2H), 7.38 (dd, J = 9.8, 8.4, 1H),7.19 (d, J = 2.1, 1H), 6.79 (d, J = 4.0, 1H), 6.10 (d,J = 3.3, 1H), 4.03 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H).::US9732094, Example 404::US11065253, Example 404	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315981	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315981&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954741	383542633							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616899	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H20FN5O2S/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-10-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	BKVDUGPHOXFCIL-UHFFFAOYSA-N	315982	US10172859, Example 405::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 9.04 (s, 1H), 8.49 (d, J = 5.5, 1H), 7.91 (dd,J = 6.9, 2.3, 1H), 7.80 (d, J = 9.4, 1H), 7.79-7.74(m, 1H), 7.63 (d, J = 5.5, 1H), 7.49 (dd, J = 9.5, 2.6,1H), 7.43 (dd, J = 9.9, 8.5, 1H), 7.21-7.15 (m, 2H),6.38 (d, J = 2.1, 1H), 3.83-3.76 (m, 4H), 3.47-3.42 (m, 4H).::US9732094, Example 405::US11065253, Example 405	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315982&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954755	383542634							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616901	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(11-19(20)24(32)23-18-5-10-34-25(18)30-14-29-23)22-17-3-2-16(12-21(17)27-13-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	VAZNQKKOJUYTLR-UHFFFAOYSA-N	315983	US10172859, Example 406::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 9.03 (s, 1H), 8.48 (d, J = 5.6, 1H), 7.90 (dd,J = 6.9, 2.3, 1H), 7.79 (d, J = 9.4, 1H), 7.78-7.73(m, 1H), 7.62 (d, J = 5.6, 1H), 7.48 (dd, J = 9.5, 2.6,1H), 7.41 (dd, J = 9.9, 8.5, 1H), 7.18 (d, J = 2.6, 1H),7.16 (d, J = 4.7, 1H), 6.36 (d, J = 4.5, 1H), 3.82-3.74 (m, 4H), 3.48-3.40 (m, 4H).::US9732094, Example 406::US11065253, Example 406	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315983	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315983&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966404	383542635							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616903	Cc1cncnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-12-28-13-30-23(15)22(25(27)33)19-10-16(2-5-20(19)26)24-18-4-3-17(11-21(18)29-14-31-24)32-6-8-34-9-7-32/h2-5,10-14,22H,6-9H2,1H3,(H2,27,33)	XNDMXGNHPWCDKX-UHFFFAOYSA-N	315953	US10172859, Example 378::2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(5-methyl- pyrimidin-4-yl)- acetamide (Ena 2)see racemate::US10172859, Example 407::US10172859, Example 377::US9732094, Example 407::US11065253, Example 407	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315953	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954832	383542615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616905	COc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-21-12-26-13-28-23(21)24(31)18-10-15(2-5-19(18)25)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	OTIHBNMSAHVGDN-UHFFFAOYSA-N	315985	US10172859, Example 413::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 409::US10172859, Example 408::US9732094, Example 413::US11065253, Example 422	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954975	383542636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616907	COc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-21-12-26-13-28-23(21)24(31)18-10-15(2-5-19(18)25)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	OTIHBNMSAHVGDN-UHFFFAOYSA-N	315985	US10172859, Example 413::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 409::US10172859, Example 408::US9732094, Example 413::US11065253, Example 422	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954975	383542636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616909	COc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QZQZLQSAQQUISA-UHFFFAOYSA-N	315987	US10172859, Example 411::US10172859, Example 422::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 410::US9732094, Example 422::US11065253, Example 411	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954914	383542637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616911	COc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QZQZLQSAQQUISA-UHFFFAOYSA-N	315987	US10172859, Example 411::US10172859, Example 422::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 410::US9732094, Example 422::US11065253, Example 411	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954914	383542637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616913	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncncc1F	InChI=1S/C23H19ClFN5O2/c24-18-4-1-14(9-17(18)23(31)22-19(25)11-26-12-28-22)21-16-3-2-15(10-20(16)27-13-29-21)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	LGZAMQCFFYGHBM-UHFFFAOYSA-N	315966	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-fluoro- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 412::US10172859, Example 390::US10172859, Example 389::US9732094, Example 412::US11065253, Example 412	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954820	383542624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616915	COc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-21-12-26-13-28-23(21)24(31)18-10-15(2-5-19(18)25)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	OTIHBNMSAHVGDN-UHFFFAOYSA-N	315985	US10172859, Example 413::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 409::US10172859, Example 408::US9732094, Example 413::US11065253, Example 422	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315985	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954975	383542636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616917	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20ClN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	UUXRSDRUPOEDCD-UHFFFAOYSA-N	315991	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 432::US10172859, Example 415::US10172859, Example 414::US9732094, Example 432::US11065253, Example 432	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954873	383542638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616919	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20ClN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	UUXRSDRUPOEDCD-UHFFFAOYSA-N	315991	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 432::US10172859, Example 415::US10172859, Example 414::US9732094, Example 432::US11065253, Example 432	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954873	383542638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616921	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2occc12	InChI=1S/C25H20ClN5O3/c26-20-4-1-15(11-19(20)24(32)23-18-5-8-34-25(18)30-14-29-23)22-17-3-2-16(12-21(17)27-13-28-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	GYTMHNSZACGKTK-UHFFFAOYSA-N	315993	US10172859, Example 416::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.88 (s, 1H), 8.20 (d, J = 2.5, 1H), 8.03 (d,J = 2.2, 1H), 7.84 (d, J = 9.4, 1H), 7.72 (dd, J = 8.2,2.2, 1H), 7.65 (d, J = 8.3, 1H), 7.52 (dd, J = 9.4, 2.6,1H), 7.26 (d, J = 2.5, 1H), 7.20 (d, J = 2.5, 1H), 6.88-6.72 (m, 1H), 6.46 (s, 1H), 3.82-3.76 (m, 4H),3.48-3.42 (m, 4H).::US9732094, Example 416::US11065253, Example 416	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315993	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315993&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966405	383542639							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616923	Cc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WWJSWAADUXDPSA-UHFFFAOYSA-N	315994	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 418::US10172859, Example 419::US10172859, Example 417::US9732094, Example 419::US11065253, Example 419	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954968	383542640							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616925	Cc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WWJSWAADUXDPSA-UHFFFAOYSA-N	315994	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 418::US10172859, Example 419::US10172859, Example 417::US9732094, Example 419::US11065253, Example 419	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954968	383542640							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616927	Cc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WWJSWAADUXDPSA-UHFFFAOYSA-N	315994	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol (Ena 2)see racemate::US10172859, Example 418::US10172859, Example 419::US10172859, Example 417::US9732094, Example 419::US11065253, Example 419	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315994	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954968	383542640							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616929	Cn1cnc2c(ncnc12)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-14-31-23-22(29-13-30-25(23)32)24(34)15-2-5-19(26)18(10-15)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	KPHDWKKIMJUEFT-UHFFFAOYSA-N	315997	US10172859, Example 420::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.91 (s, 1H), 8.55 (s, 1H), 7.82-7.73 (m,2H), 7.56-7.47 (m, 2H), 7.40-7.31 (m, 1H),7.19 (d, J = 1.3, 1H), 6.43 (d, J = 3.0, 1H), 6.30 (d,J = 5.2, 1H), 3.83 (s, 3H), 3.81-3.75 (m, 4H), 3.47-3.40 (m, 4H).::US9732094, Example 420::US11065253, Example 420	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315997	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315997&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954901	383542641							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616931	Cn1cnc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-13-32-23-22(30-12-31-25(23)33)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	YUNSFHVJJPXAJL-UHFFFAOYSA-N	315922	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 421::US10172859, Example 347::US10172859, Example 346::US9732094, Example 421::US11065253, Example 421	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315922	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954880	383542591							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616933	COc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QZQZLQSAQQUISA-UHFFFAOYSA-N	315987	US10172859, Example 411::US10172859, Example 422::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 410::US9732094, Example 422::US11065253, Example 411	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315987	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954914	383542637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616935	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3Cl)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21ClFN7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)16-9-17(19(27)10-18(16)26)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	GOQCONHIZCNEEW-UHFFFAOYSA-N	316000	US10172859, Example 423::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 8.83 (s, 1H), 8.69 (s, 1H), 8.01 (d, J = 7.8,1H), 7.71-7.63 (m, 2H), 7.59 (dd, J = 9.4, 2.5, 1H),7.22 (d, J = 2.4, 1H), 6.87 (d, J = 6.3, 1H), 6.66 (d,J = 6.3, 1H), 4.25 (s, 3H), 3.84-3.73 (m, 4H), 3.52-3.42 (m, 4H).::US9732094, Example 423	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316000	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316000&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954792	383542642							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616937	CN1CCN(C1=O)c1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H26FN7O3/c1-33-8-9-35(27(33)37)26-24(29-6-7-30-26)25(36)17-2-5-21(28)20(14-17)23-19-4-3-18(15-22(19)31-16-32-23)34-10-12-38-13-11-34/h2-7,14-16,25,36H,8-13H2,1H3	YOWUVCMEWRRBJL-UHFFFAOYSA-N	316001	US10172859, Example 424::1-(3-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl)- 3-methyl- imidazolidin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.50 (d, J = 2.4, 1H), 8.43 (d, J = 2.4, 1H), 7.69-7.59 (m, 2H), 7.59-7.49 (m, 2H), 7.35 (t, J = 9.2,1H), 7.19 (d, J = 1.9, 1H), 6.23 (d, J = 4.4, 1H), 5.95(d, J = 5.3, 1H), 3.85 (t, J = 7.8, 2H), 3.82-3.73 (m,4H), 3.52-3.40 (m, 6H), 2.78 (s, 3H).::US9732094, Example 424::US11065253, Example 424	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316001	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966406	383542643							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616939	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1N1CCCC1=O	InChI=1S/C27H25FN6O3/c28-21-6-3-17(26(36)25-27(30-8-7-29-25)34-9-1-2-23(34)35)14-20(21)24-19-5-4-18(15-22(19)31-16-32-24)33-10-12-37-13-11-33/h3-8,14-16,26,36H,1-2,9-13H2	HAKJGZGJAFAOJJ-UHFFFAOYSA-N	316002	US10172859, Example 425::1-(3-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl)- pyrrolidin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.61 (d, J = 2.4, 1H), 8.52 (d, J = 2.4, 1H), 7.65-7.56 (m, 2H), 7.56-7.49 (m, 2H), 7.36 (t, J = 9.5,1H), 7.19 (s, 1H), 6.02 (s, 2H), 3.89-3.82 (m,1H), 3.81-3.74 (m, 4H), 3.74-3.64 (m, 1H),3.50-3.39 (m, 4H), 2.57-2.41 (m, 2H), 2.17-2.08 (m, 1H), 2.07-1.98 (m, 1H).::US9732094, Example 425::US11065253, Example 425	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316002	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316002&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954798	383542644							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616941	Cc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	KQRMNHUHQIGCCV-UHFFFAOYSA-N	316003	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 427::US10172859, Example 428::US10172859, Example 426::US9732094, Example 428::US11065253, Example 428	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954949	383542645							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616943	Cc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	KQRMNHUHQIGCCV-UHFFFAOYSA-N	316003	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 427::US10172859, Example 428::US10172859, Example 426::US9732094, Example 428::US11065253, Example 428	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954949	383542645							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616945	Cc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	KQRMNHUHQIGCCV-UHFFFAOYSA-N	316003	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 2)see racemate::US10172859, Example 427::US10172859, Example 428::US10172859, Example 426::US9732094, Example 428::US11065253, Example 428	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316003	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954949	383542645							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616947	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H19ClFN5O2S/c26-19-11-20(27)18(10-17(19)24(33)23-16-3-8-35-25(16)31-13-30-23)22-15-2-1-14(9-21(15)28-12-29-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	WSXQRVAJDUCHLW-UHFFFAOYSA-N	316006	US10172859, Example 429::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 9.05 (s, 1H), 8.46 (d, J = 5.6, 1H), 7.75 (d,J = 7.6, 1H), 7.72 (d, J = 9.6, 1H), 7.61 (d, J = 5.6,1H), 7.55-7.49 (m, 2H), 7.20 (d, J = 5.0, 1H), 7.19-7.17 (m, 1H), 6.42 (d, J = 5.1, 1H), 3.80-3.75 (m,4H), 3.46-3.42 (m, 4H).::US9732094, Example 429::US11065253, Example 429	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316006	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316006&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954864	383542646							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616949	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H20ClN5O2S/c26-20-4-1-15(11-19(20)24(32)23-18-5-10-34-25(18)30-14-29-23)22-17-3-2-16(12-21(17)27-13-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	HTXWHKWAFKZIOM-UHFFFAOYSA-N	316007	US10172859, Example 430::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 9.04 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.89 (d,J = 2.1, 1H), 7.76 (d, J = 9.4, 1H), 7.73 (dd, J = 8.2,2.2, 1H), 7.69 (d, J = 8.3, 1H), 7.62 (d, J = 5.5, 1H),7.47 (dd, J = 9.5, 2.6, 1H), 7.20-7.16 (m, 2H),6.47 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H).::US9732094, Example 430::US11065253, Example 430	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316007	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316007&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966407	383542647							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616951	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3F)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21F2N7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	VGKMJMNCNMRSEO-UHFFFAOYSA-N	315961	US10172859, Example 386::US10172859, Example 431::(R)-[2,4-Difluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 384::US9732094, Example 431::US11065253, Example 431	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315961	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954829	383542620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616953	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20ClN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	UUXRSDRUPOEDCD-UHFFFAOYSA-N	315991	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 432::US10172859, Example 415::US10172859, Example 414::US9732094, Example 432::US11065253, Example 432	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954873	383542638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616955	Cn1cnc2ncnc(C(O)c3ccc(F)c(c3)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H22FN7O2/c1-32-14-31-25-23(32)22(29-13-30-25)24(34)15-2-5-19(26)18(10-15)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	ZMFSOBGRZBTGEQ-UHFFFAOYSA-N	316010	US10172859, Example 433::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.90 (s, 1H), 8.60 (s, 1H), 7.68-7.60 (m,2H), 7.56 (dd, J = 9.4, 2.8, 1H), 7.52 (dd, J = 9.4,2.4, 1H), 7.44-7.38 (m, 1H), 7.19 (d, J = 2.3, 1H),6.84 (d, J = 5.5, 1H), 6.37 (d, J = 5.4, 1H), 4.04 (s,3H), 3.81-3.75 (m, 4H), 3.47-3.41 (m, 4H).::US9732094, Example 433::US11065253, Example 433	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316010	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316010&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954982	383542648							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616957	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2occc12	InChI=1S/C25H20FN5O3/c26-20-4-1-15(24(32)23-18-5-8-34-25(18)30-14-29-23)11-19(20)22-17-3-2-16(12-21(17)27-13-28-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	OLAPWLJTKZZIJG-UHFFFAOYSA-N	316011	US10172859, Example 434::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.89 (s, 1H), 8.18 (d, J = 2.5, 1H), 7.77-7.72(m, 2H), 7.54-7.47 (m, 2H), 7.40 (t, J = 9.5, 1H),7.36 (d, J = 2.5, 1H), 7.20 (d, J = 2.2, 1H), 6.71 (d,J = 4.2, 1H), 6.13 (d, J = 4.2, 1H), 3.81-3.76 (m,4H), 3.47-3.42 (m, 4H).::US9732094, Example 434	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316011	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316011&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696483	383542649							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616959	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-30-22(3-2-4-23(30)32)25(33)17-12-18(20(27)13-19(17)26)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	WYNSFINJUTXESJ-UHFFFAOYSA-N	315959	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 435::US10172859, Example 383::US10172859, Example 382::US9732094, Example 435::US11065253, Example 435	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315959	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696425	383542619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616961	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-30-22(3-2-4-23(30)32)25(33)18-12-17(19(26)13-20(18)27)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	TYEQLJVPHLCAPI-UHFFFAOYSA-N	315957	US10172859, Example 436::6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 381::US10172859, Example 380::US9732094, Example 436::US11065253, Example 436	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315957	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954779	383542618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616963	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(24(32)23-18-5-10-34-25(18)30-14-29-23)11-19(20)22-17-3-2-16(12-21(17)27-13-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	OPFDCXZLQFZOBI-UHFFFAOYSA-N	316014	US10172859, Example 437::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 9.08 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.78-7.73(m, 2H), 7.61 (d, J = 5.6, 1H), 7.54-7.46 (m, 2H),7.43-7.36 (m, 1H), 7.21-7.18 (m, 1H), 7.13 (d,J = 3.9, 1H), 6.12 (d, J = 3.9, 1H), 3.82-3.73 (m,4H), 3.48-3.40 (m, 4H).::US9732094, Example 437::US11065253, Example 437	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316014	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316014&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966408	383542650							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616965	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H20FN5O2S/c26-19-4-1-15(24(32)23-25-20(5-10-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	RGLFQGKKFJSQEU-UHFFFAOYSA-N	316015	US10172859, Example 438::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 9.07 (s, 1H), 8.46 (s, 1H), 8.45 (s, 1H), 7.78-7.73 (m, 2H), 7.60 (d, J = 5.5, 1H), 7.52-7.46 (m,2H), 7.41-7.36 (m, 1H), 7.20-7.18 (m, 1H),7.11 (d, J = 3.9, 1H), 6.12 (d, J = 3.9, 1H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H).::US9732094, Example 438::US11065253, Example 438	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316015	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316015&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966409	383542651							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616967	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H19F2N5O2S/c26-18-11-19(27)17(24(33)23-25-20(3-8-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	YGCAKHZAOVAPCB-UHFFFAOYSA-N	316016	US10172859, Example 439::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 9.05 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.76 (t,J = 8.0, 1H), 7.61 (d, J = 5.6, 1H), 7.54-7.46 (m,3H), 7.21-7.16 (m, 2H), 6.32 (d, J = 4.8, 1H), 3.80-3.74 (m, 4H), 3.46-3.41 (m, 4H).::US9732094, Example 439::US11065253, Example 439	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316016	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316016&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954767	383542652							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616969	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19ClFN5O3/c26-18-11-19(27)17(10-16(18)24(33)23-25-20(3-6-35-25)28-12-31-23)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	RSORSFFEQKYDEH-UHFFFAOYSA-N	316017	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 441::US10172859, Example 452::US10172859, Example 440::US9732094, Example 452::US11065253, Example 452	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954743	383542653							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616971	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19ClFN5O3/c26-18-11-19(27)17(10-16(18)24(33)23-25-20(3-6-35-25)28-12-31-23)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	RSORSFFEQKYDEH-UHFFFAOYSA-N	316017	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 441::US10172859, Example 452::US10172859, Example 440::US9732094, Example 452::US11065253, Example 452	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954743	383542653							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616973	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(24(32)23-25-20(5-8-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	ALDDQCBBKGTAJI-UHFFFAOYSA-N	316019	US10172859, Example 443::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 471::US10172859, Example 442::US9732094, Example 471::US11065253, Example 471	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954900	383542654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616975	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(24(32)23-25-20(5-8-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	ALDDQCBBKGTAJI-UHFFFAOYSA-N	316019	US10172859, Example 443::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 471::US10172859, Example 442::US9732094, Example 471::US11065253, Example 471	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954900	383542654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616977	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19F2N5O3/c26-18-11-19(27)17(24(33)23-25-20(3-6-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JBAPBICUWYTLAE-UHFFFAOYSA-N	316021	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 445::US10172859, Example 446::US10172859, Example 444::US9732094, Example 446::US11065253, Example 446	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954757	383542655							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616979	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19F2N5O3/c26-18-11-19(27)17(24(33)23-25-20(3-6-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JBAPBICUWYTLAE-UHFFFAOYSA-N	316021	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 445::US10172859, Example 446::US10172859, Example 444::US9732094, Example 446::US11065253, Example 446	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954757	383542655							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616981	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19F2N5O3/c26-18-11-19(27)17(24(33)23-25-20(3-6-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JBAPBICUWYTLAE-UHFFFAOYSA-N	316021	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 445::US10172859, Example 446::US10172859, Example 444::US9732094, Example 446::US11065253, Example 446	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316021	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954757	383542655							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616983	COc1cncnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-21-11-27-12-29-23(21)24(32)16-9-17(19(26)10-18(16)25)22-15-3-2-14(8-20(15)28-13-30-22)31-4-6-34-7-5-31/h2-3,8-13,24,32H,4-7H2,1H3	YEVSBZQJDDCQFS-UHFFFAOYSA-N	316024	US10172859, Example 447::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.14 (s,1H), 8.74 (s, 1H), 8.65 (s, 1H), 7.97 (d, J = 7.9,1H), 7.69-7.52 (m, 3H), 7.23 (d, J = 2.4, 1H), 6.43-6.32 (m, 2H), 4.01 (s, 3H), 3.80 (dd, J = 5.9, 3.9,4H), 3.47 (t, J = 4.9, 4H).::US9732094, Example 447::US11065253, Example 447	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316024	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316024&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954881	383542656							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616985	COc1cncnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-11-27-12-29-23(21)24(32)17-9-16(18(25)10-19(17)26)22-15-3-2-14(8-20(15)28-13-30-22)31-4-6-34-7-5-31/h2-3,8-13,24,32H,4-7H2,1H3	MYZXVIJFUGZRRE-UHFFFAOYSA-N	316025	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.77 (s, 1H), 8.62 (s, 1H), 7.86 (t, J = 8.2,1H), 7.66-7.50 (m, 2H), 7.41 (t, J = 10.1, 1H),7.21 (d, J = 2.1, 1H), 6.32 (d, J = 6.2, 1H), 6.25 (d,J = 6.3, 1H), 3.97 (s, 3H), 3.78 (t, J = 4.9, 4H), 3.45(t, J = 4.9, 4H).::US10172859, Example 448::US9732094, Example 448::US11065253, Example 448	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316025	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316025&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954903	383542657							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616987	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H19F4N5O3/c25-17-11-18(26)16(22(34)21-23(36-24(27)28)30-4-3-29-21)10-15(17)20-14-2-1-13(9-19(14)31-12-32-20)33-5-7-35-8-6-33/h1-4,9-12,22,24,34H,5-8H2	DZAPMQOMKQTQIL-UHFFFAOYSA-N	316027	US10172859, Example 450::US10172859, Example 451::(3-Difluoromethoxy- pyrazin-2-yl)-[2,4- difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol (Ena 2)see racemate::US10172859, Example 449::US9732094, Example 451	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954883	383542659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616989	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H19F4N5O3/c25-17-11-18(26)16(22(34)21-23(36-24(27)28)30-4-3-29-21)10-15(17)20-14-2-1-13(9-19(14)31-12-32-20)33-5-7-35-8-6-33/h1-4,9-12,22,24,34H,5-8H2	DZAPMQOMKQTQIL-UHFFFAOYSA-N	316027	US10172859, Example 450::US10172859, Example 451::(3-Difluoromethoxy- pyrazin-2-yl)-[2,4- difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol (Ena 2)see racemate::US10172859, Example 449::US9732094, Example 451	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954883	383542659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616991	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H19F4N5O3/c25-17-11-18(26)16(22(34)21-23(36-24(27)28)30-4-3-29-21)10-15(17)20-14-2-1-13(9-19(14)31-12-32-20)33-5-7-35-8-6-33/h1-4,9-12,22,24,34H,5-8H2	DZAPMQOMKQTQIL-UHFFFAOYSA-N	316027	US10172859, Example 450::US10172859, Example 451::(3-Difluoromethoxy- pyrazin-2-yl)-[2,4- difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol (Ena 2)see racemate::US10172859, Example 449::US9732094, Example 451	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316027	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954883	383542659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616993	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19ClFN5O3/c26-18-11-19(27)17(10-16(18)24(33)23-25-20(3-6-35-25)28-12-31-23)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	RSORSFFEQKYDEH-UHFFFAOYSA-N	316017	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 441::US10172859, Example 452::US10172859, Example 440::US9732094, Example 452::US11065253, Example 452	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316017	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954743	383542653							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616995	COc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316031	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 1)see racemate::US10172859, Example 454::US10172859, Example 467::US10172859, Example 453::US9732094, Example 467::US11065253, Example 467	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696480	383542660							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616997	COc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316031	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 1)see racemate::US10172859, Example 454::US10172859, Example 467::US10172859, Example 453::US9732094, Example 467::US11065253, Example 467	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696480	383542660							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
616999	COc1nccnc1[C@H](O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316033	(R)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 455::US11065253, Example 455	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316033	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316033&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			131997347	383542661							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617001	COc1nccnc1[C@@H](O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1 |r|	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316034	(S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 456::US11065253, Example 456	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316034	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316034&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			131997348	383542662							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617003	Cc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O2/c1-14-22(28-5-4-27-14)24(32)17-11-18(20(26)12-19(17)25)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	RUVXWPONRWXAMN-UHFFFAOYSA-N	316035	[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s,1H), 8.43 (d, J = 2.5, 1H), 8.36 (d, J = 2.5, 1H), 7.99(d, J = 7.8, 1H), 7.67-7.60 (m, 2H), 7.57 (dd,J = 9.4, 2.5, 1H), 7.22 (d, J = 2.4, 1H), 6.44 (d,J = 5.9, 1H), 6.25 (d, J = 5.6, 1H), 3.86-3.72 (m,4H), 3.52-3.42 (m, 4H), 2.74 (s, 3H).::US10172859, Example 457::US9732094, Example 457::US11065253, Example 457	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316035	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316035&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954904	383542663							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617005	COc1ccc(nn1)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QSHKWVVOMGJBJQ-UHFFFAOYSA-N	316036	US10172859, Example 459::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.07 (d, J = 2.2, 1H), 7.89 (d, J = 9.5, 1H), 7.73-7.67 (m, 2H), 7.63 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.24-7.19 (m, 2H), 6.59 (d,J = 4.8, 1H), 6.28 (d, J = 4.8, 1H), 4.00 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.41 (m, 4H).::US10172859, Example 460::US10172859, Example 458::US9732094, Example 460::US11065253, Example 460	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954970	383542664							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617007	COc1ccc(nn1)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QSHKWVVOMGJBJQ-UHFFFAOYSA-N	316036	US10172859, Example 459::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.07 (d, J = 2.2, 1H), 7.89 (d, J = 9.5, 1H), 7.73-7.67 (m, 2H), 7.63 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.24-7.19 (m, 2H), 6.59 (d,J = 4.8, 1H), 6.28 (d, J = 4.8, 1H), 4.00 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.41 (m, 4H).::US10172859, Example 460::US10172859, Example 458::US9732094, Example 460::US11065253, Example 460	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954970	383542664							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617009	COc1ccc(nn1)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QSHKWVVOMGJBJQ-UHFFFAOYSA-N	316036	US10172859, Example 459::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.07 (d, J = 2.2, 1H), 7.89 (d, J = 9.5, 1H), 7.73-7.67 (m, 2H), 7.63 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.24-7.19 (m, 2H), 6.59 (d,J = 4.8, 1H), 6.28 (d, J = 4.8, 1H), 4.00 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.41 (m, 4H).::US10172859, Example 460::US10172859, Example 458::US9732094, Example 460::US11065253, Example 460	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316036	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954970	383542664							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617011	Cn1cnc2ccnc(C(O)c3ccc(F)c(c3)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C26H23FN6O2/c1-32-15-31-21-6-7-28-24(25(21)32)26(34)16-2-5-20(27)19(12-16)23-18-4-3-17(13-22(18)29-14-30-23)33-8-10-35-11-9-33/h2-7,12-15,26,34H,8-11H2,1H3	NSLYODQLWMOYDK-UHFFFAOYSA-N	316039	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- 3H-imidazo[4,5-c]- pyridin-4-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.33 (s, 1H), 8.25 (d, J = 5.5, 1H), 7.62 (d,J = 5.5, 1H), 7.61-7.50 (m, 4H), 7.42-7.37 (m,1H), 7.19 (d, J = 2.3, 1H), 6.61 (d, J = 5.5, 1H), 6.43(d, J = 5.4, 1H), 4.01 (s, 3H), 3.80-3.74 (m, 4H),3.46-3.41 (m, 4H).::US10172859, Example 461::US9732094, Example 461::US11065253, Example 461	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954736	383542665							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617013	CCc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O2/c1-2-21-24(28-8-7-27-21)25(32)16-3-6-20(26)19(13-16)23-18-5-4-17(14-22(18)29-15-30-23)31-9-11-33-12-10-31/h3-8,13-15,25,32H,2,9-12H2,1H3	OHCNFGVQULWIRH-UHFFFAOYSA-N	316040	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-iodo- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.62 (d, J = 2.4, 1H), 8.37 (d, J = 2.4, 1H), 7.69-7.61 (m, 2H), 7.58-7.49 (m, 2H), 7.44-7.36 (m,1H), 7.22-7.17 (m, 1H), 6.33 (d, J = 5.7, 1H), 6.17(d, J = 5.7, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).::US10172859, Example 462::US9732094, Example 462	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316040	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316040&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966411	383542666							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617015	CCOc1cccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H25FN4O3/c1-2-34-23-4-3-9-28-25(23)26(32)17-5-8-21(27)20(14-17)24-19-7-6-18(15-22(19)29-16-30-24)31-10-12-33-13-11-31/h3-9,14-16,26,32H,2,10-13H2,1H3	UTBHMAUJPAIFTH-UHFFFAOYSA-N	316041	(3-Ethoxy-pyridin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.14 (dd, J = 4.7, 1.2, 1H), 7.63-7.55 (m, 2H),7.55-7.47 (m, 2H), 7.41 (dd, J = 8.3, 1.3, 1H),7.38-7.31 (m, 1H), 7.29 (dd, J = 8.3, 4.7, 1H),7.21-7.17 (m, 1H), 6.07 (d, J = 6.3, 1H), 5.79 (d,J = 6.6, 1H), 4.06 (q, J = 7.0, 2H), 3.81-3.75 (m,4H), 3.47-3.41 (m, 4H), 1.28 (t, J = 6.9, 3H).::US10172859, Example 463::US9732094, Example 463::US11065253, Example 463	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316041	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316041&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954738	383542667							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617017	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H20F3N5O3/c25-18-4-1-14(22(33)21-23(35-24(26)27)29-6-5-28-21)11-17(18)20-16-3-2-15(12-19(16)30-13-31-20)32-7-9-34-10-8-32/h1-6,11-13,22,24,33H,7-10H2	WUQGHORGFLTBFV-UHFFFAOYSA-N	316042	(3-Difluoromethoxy- pyrazin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.51 (d, J = 2.6, 1H), 8.28 (d, J = 2.6, 1H), 7.86-7.55 (m, 3H), 7.54-7.49 (m, 2H), 7.43-7.36 (m,1H), 7.22-7.17 (m, 1H), 6.30 (d, J = 5.6, 1H), 6.10(d, J = 4.9, 1H), 3.83-3.73 (m, 4H), 3.48-3.40 (m,4H).::US10172859, Example 464::US9732094, Example 464	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316042	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316042&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954927	383542668							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617019	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C24H20ClFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	IKPAUHLVUSUQBQ-UHFFFAOYSA-N	315616	US10172859, Example 465::US10172859, Example 466::(3-Chloro-pyridin-2-yl)- [4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.56 (dd, J = 4.6, 1.4, 1H), 7.92 (dd, J = 8.1, 1.4, 1H), 7.64-7.59 (m, 2H), 7.54-7.49 (m, 2H), 7.40- 7.34 (m, 2H), 7.22-7.17 (m, 1H), 6.21 (s, 1H), 6.18-6.09 (m, 1H), 3.81-3.73 (m, 4H), 3.48- 3.40 (m, 4H)::US10172859, Example 42::US9732094, Example 466::US11065253, Example 42	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292074	383542366							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617021	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C24H20ClFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	IKPAUHLVUSUQBQ-UHFFFAOYSA-N	315616	US10172859, Example 465::US10172859, Example 466::(3-Chloro-pyridin-2-yl)- [4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.56 (dd, J = 4.6, 1.4, 1H), 7.92 (dd, J = 8.1, 1.4, 1H), 7.64-7.59 (m, 2H), 7.54-7.49 (m, 2H), 7.40- 7.34 (m, 2H), 7.22-7.17 (m, 1H), 6.21 (s, 1H), 6.18-6.09 (m, 1H), 3.81-3.73 (m, 4H), 3.48- 3.40 (m, 4H)::US10172859, Example 42::US9732094, Example 466::US11065253, Example 42	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315616	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292074	383542366							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617023	COc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316031	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 1)see racemate::US10172859, Example 454::US10172859, Example 467::US10172859, Example 453::US9732094, Example 467::US11065253, Example 467	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316031	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696480	383542660							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617025	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 242::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate::US10172859, Example 258::US10172859, Example 468::US10172859, Example 241::US9732094, Example 258::US11065253, Example 258	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617027	OC(c1cccnn1)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClN5O2/c24-19-6-3-15(12-18(19)23(30)20-2-1-7-27-28-20)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	NKTVIVGVBABPLJ-UHFFFAOYSA-N	316047	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridazin-3-yl- methanol (Ena 2)see racemate::US10172859, Example 479::US10172859, Example 470::US10172859, Example 469::US9732094, Example 479::US11065253, Example 479	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954953	383542669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617029	OC(c1cccnn1)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClN5O2/c24-19-6-3-15(12-18(19)23(30)20-2-1-7-27-28-20)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	NKTVIVGVBABPLJ-UHFFFAOYSA-N	316047	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridazin-3-yl- methanol (Ena 2)see racemate::US10172859, Example 479::US10172859, Example 470::US10172859, Example 469::US9732094, Example 479::US11065253, Example 479	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954953	383542669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617031	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(24(32)23-25-20(5-8-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	ALDDQCBBKGTAJI-UHFFFAOYSA-N	316019	US10172859, Example 443::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate::US10172859, Example 471::US10172859, Example 442::US9732094, Example 471::US11065253, Example 471	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316019	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954900	383542654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617033	Cc1cccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O2/c1-16-3-2-8-27-23(16)25(31)17-4-7-21(26)20(13-17)24-19-6-5-18(14-22(19)28-15-29-24)30-9-11-32-12-10-30/h2-8,13-15,25,31H,9-12H2,1H3	GBYLJBVPBPYLRC-UHFFFAOYSA-N	316050	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyridin-2-yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.43-8.39 (m, 1H), 7.63-7.57 (m, 1H),7.56-7.49 (m, 4H), 7.39-7.32 (m, 1H), 7.28-7.23 (m, 1H), 7.21-7.17 (m, 1H), 6.09 (s, 1H),6.01 (s, 1H), 3.82-3.73 (m, 4H), 3.48-3.40 (m,4H), 2.28 (s, 3H).::US10172859, Example 472::US9732094, Example 472	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316050	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316050&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954737	383542670							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617035	COc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Br)c1	InChI=1S/C25H22BrFN4O3/c1-33-17-12-20(26)24(28-13-17)25(32)15-2-5-21(27)19(10-15)23-18-4-3-16(11-22(18)29-14-30-23)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	ZLJHQDMTGQKOCX-UHFFFAOYSA-N	316051	(3-bromo-5-methoxy- pyridin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.31 (d, J = 2.6, 1H), 7.70 (d, J = 2.6, 1H), 7.62-7.56 (m, 2H), 7.54-7.50 (m, 2H), 7.39-7.33 (m,1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.01(d, J = 6.1, 1H), 3.84 (s, 3H), 3.80-3.75 (m, 4H),3.46-3.41 (m, 4H).::US10172859, Example 473::US9732094, Example 473::US11065253, Example 473	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316051	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316051&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954989	383542671							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617037	OC(c1cn2ccsc2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H19F2N5O2S/c25-18-11-19(26)17(23(32)21-12-31-5-8-34-24(31)29-21)10-16(18)22-15-2-1-14(9-20(15)27-13-28-22)30-3-6-33-7-4-30/h1-2,5,8-13,23,32H,3-4,6-7H2	IHQLBTUWFJZXJZ-UHFFFAOYSA-N	316052	[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [2,1-b]thiazol-6-yl- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.85 (d, J = 4.5, 1H), 7.71-7.68 (m, 1H), 7.62-7.55 (m, 1H), 7.54-7.51 (m, 2H), 7.26 (t, J = 9.1,1H), 7.21-7.17 (m, 2H), 6.18-6.13 (m, 2H),3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 474::US9732094, Example 474::US11065253, Example 474	Potassium voltage-gated channel subfamily H member 2	Human	 12500								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966412	383542672							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617039	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1OC(F)(F)F	InChI=1S/C25H20F4N4O3/c26-19-6-3-15(24(34)23-21(2-1-7-30-23)36-25(27,28)29)12-18(19)22-17-5-4-16(13-20(17)31-14-32-22)33-8-10-35-11-9-33/h1-7,12-14,24,34H,8-11H2	OBAUKTZXPTWSGG-UHFFFAOYSA-N	316053	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-trifluoro- methoxypyridin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.61 (dd, J = 4.6, 1.3, 1H), 7.87 (dp, J = 8.4,1.6, 1H), 7.69-7.57 (m, 2H), 7.57-7.46 (m, 3H),7.40 (dd, J = 9.9, 8.4, 1H), 7.21 (d, J = 1.9, 1H), 6.26(d, J = 5.9, 1H), 6.13 (d, J = 5.9, 1H), 3.89-3.65 (m,4H), 3.54-3.38 (m, 4H).::US10172859, Example 475::US9732094, Example 475::US11065253, Example 475	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316053	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316053&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954867	383542673							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617041	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C(F)(F)F	InChI=1S/C24H19F4N5O2/c25-18-4-1-14(22(34)21-23(24(26,27)28)30-6-5-29-21)11-17(18)20-16-3-2-15(12-19(16)31-13-32-20)33-7-9-35-10-8-33/h1-6,11-13,22,34H,7-10H2	SRYGCCCAHLEYHR-UHFFFAOYSA-N	316055	[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-trifluoro- methylpyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 9.00 (d, J = 2.3, 1H), 8.77 (d, J = 2.3, 1H), 7.66(dd, J = 6.9, 2.3, 1H), 7.63-7.59 (m, 1H), 7.56-7.50 (m, 2H), 7.43-7.37 (m, 1H), 7.21-7.18 (m,1H), 6.54 (d, J = 5.7, 1H), 6.21 (d, J = 4.3, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H).::US10172859, Example 476::US9732094, Example 476::US11065253, Example 476	Potassium voltage-gated channel subfamily H member 2	Human	>25000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316055	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316055&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954911	383542675							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617043	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Br	InChI=1S/C24H20BrFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	AOTYAPLNLRAVPH-UHFFFAOYSA-N	316056	(3-bromo-pyridin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.60 (dd, J = 4.6, 1.4, 1H), 8.08 (dd, J = 8.1,1.5, 1H), 7.65-7.59 (m, 2H), 7.54-7.50 (m, 2H),7.41-7.34 (m, 1H), 7.29 (dd, J = 8.1, 4.6, 1H),7.21-7.18 (m, 1H), 6.20 (d, J = 6.3, 1H), 6.12 (d,J = 6.3, 1H), 3.82-3.74 (m, 4H), 3.49-3.40 (m,4H).::US10172859, Example 478::US9732094, Example 478::US11065253, Example 478	Potassium voltage-gated channel subfamily H member 2	Human	<10000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316056	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316056&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954893	383542676							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
617045	OC(c1cccnn1)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClN5O2/c24-19-6-3-15(12-18(19)23(30)20-2-1-7-27-28-20)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	NKTVIVGVBABPLJ-UHFFFAOYSA-N	316047	[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridazin-3-yl- methanol (Ena 2)see racemate::US10172859, Example 479::US10172859, Example 470::US10172859, Example 469::US9732094, Example 479::US11065253, Example 479	Potassium voltage-gated channel subfamily H member 2	Human	 20000								US Patent		10.7270/Q23B626S		aid1796519	US10172859	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	1/8/2019	4/30/2019	Merck Patent	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316047	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954953	383542669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625154	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1	InChI=1S/C13H15Br2N5O2/c1-2-19-9-7-8(14)10(15)12(20(21)22)11(9)17-13(19)18-5-3-16-4-6-18/h7,16H,2-6H2,1H3	UNUPAGHCXHMCOJ-UHFFFAOYSA-N	319752	US10174013, Example 1A::US10174013, Example 1X::US10174013, Example 1Y	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1600							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			76286822	384223040							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625155	CCn1c(nc2c(C#N)c(Br)c(Br)cc12)N1CCN(CC1)C(=O)OC(C)(C)C	InChI=1S/C19H23Br2N5O2/c1-5-26-14-10-13(20)15(21)12(11-22)16(14)23-17(26)24-6-8-25(9-7-24)18(27)28-19(2,3)4/h10H,5-9H2,1-4H3	ZCNZEMWIUOVGDU-UHFFFAOYSA-N	319753	US10174013, Example 8A	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 770							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319753&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240556	384223041							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625156	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNC(=O)C1	InChI=1S/C13H13Br2N5O3/c1-2-19-8-5-7(14)10(15)12(20(22)23)11(8)17-13(19)18-4-3-16-9(21)6-18/h5H,2-4,6H2,1H3,(H,16,21)	SAYBIVBDZZTHFR-UHFFFAOYSA-N	319755	US10174013, Example 22A::US10174013, Example 22AB::US10174013, Example 22J::US10174013, Example 22L::US10174013, Example 22R	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 850							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319755&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240547	384223043							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625157	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNC(=O)C1	InChI=1S/C13H13Br2N5O3/c1-2-19-8-5-7(14)10(15)12(20(22)23)11(8)17-13(19)18-4-3-16-9(21)6-18/h5H,2-4,6H2,1H3,(H,16,21)	SAYBIVBDZZTHFR-UHFFFAOYSA-N	319755	US10174013, Example 22A::US10174013, Example 22AB::US10174013, Example 22J::US10174013, Example 22L::US10174013, Example 22R	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1780							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319755&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240547	384223043							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625158	CCCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1	InChI=1S/C14H17Br2N5O2/c1-2-5-20-10-8-9(15)11(16)13(21(22)23)12(10)18-14(20)19-6-3-17-4-7-19/h8,17H,2-7H2,1H3	SFJBMBUPQJTMMK-UHFFFAOYSA-N	319757	US10174013, Example 1M	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 520							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319757&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118524609	384223044							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625159	CC(C)Cn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1	InChI=1S/C15H19Br2N5O2/c1-9(2)8-21-11-7-10(16)12(17)14(22(23)24)13(11)19-15(21)20-5-3-18-4-6-20/h7,9,18H,3-6,8H2,1-2H3	YGNQUIKHDDXWIE-UHFFFAOYSA-N	319758	US10174013, Example 1N	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1280							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319758	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319758&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118524561	384223045							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625160	CC(C)(C)OC(=O)N1CCN(CC1)c1nc2c(c(Br)c(Br)cc2[nH]1)[N+]([O-])=O	InChI=1S/C16H19Br2N5O4/c1-16(2,3)27-15(24)22-6-4-21(5-7-22)14-19-10-8-9(17)11(18)13(23(25)26)12(10)20-14/h8H,4-7H2,1-3H3,(H,19,20)	RXGDDWPITVSKDR-UHFFFAOYSA-N	319759	US10174013, Example 2A::US10174013, Example 2C::US10174013, Example 2D	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3060							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90239675	384223046							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625161	CCCn1c(NCCCN)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C13H17Br2N5O2/c1-2-6-19-9-7-8(14)10(15)12(20(21)22)11(9)18-13(19)17-5-3-4-16/h7H,2-6,16H2,1H3,(H,17,18)	CHRYBQVWWPSGLL-UHFFFAOYSA-N	319760	US10174013, Example 1P	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1880							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319760&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144695	384223047							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625162	CC(C)(C)OC(=O)N1CCN(CC1)c1nc2c(c(Br)c(Br)cc2[nH]1)[N+]([O-])=O	InChI=1S/C16H19Br2N5O4/c1-16(2,3)27-15(24)22-6-4-21(5-7-22)14-19-10-8-9(17)11(18)13(23(25)26)12(10)20-14/h8H,4-7H2,1-3H3,(H,19,20)	RXGDDWPITVSKDR-UHFFFAOYSA-N	319759	US10174013, Example 2A::US10174013, Example 2C::US10174013, Example 2D	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2500							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90239675	384223046							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625163	CC(C)(C)OC(=O)N1CCN(CC1)c1nc2c(c(Br)c(Br)cc2[nH]1)[N+]([O-])=O	InChI=1S/C16H19Br2N5O4/c1-16(2,3)27-15(24)22-6-4-21(5-7-22)14-19-10-8-9(17)11(18)13(23(25)26)12(10)20-14/h8H,4-7H2,1-3H3,(H,19,20)	RXGDDWPITVSKDR-UHFFFAOYSA-N	319759	US10174013, Example 2A::US10174013, Example 2C::US10174013, Example 2D	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1600							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90239675	384223046							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625164	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1	InChI=1S/C13H15Br2N5O2/c1-2-19-9-7-8(14)10(15)12(20(21)22)11(9)17-13(19)18-5-3-16-4-6-18/h7,16H,2-6H2,1H3	UNUPAGHCXHMCOJ-UHFFFAOYSA-N	319752	US10174013, Example 1A::US10174013, Example 1X::US10174013, Example 1Y	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20420							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			76286822	384223040							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625165	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1	InChI=1S/C13H15Br2N5O2/c1-2-19-9-7-8(14)10(15)12(20(21)22)11(9)17-13(19)18-5-3-16-4-6-18/h7,16H,2-6H2,1H3	UNUPAGHCXHMCOJ-UHFFFAOYSA-N	319752	US10174013, Example 1A::US10174013, Example 1X::US10174013, Example 1Y	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16910							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319752&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			76286822	384223040							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625166	CCn1c(N[C@H]2CCCNC2)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C14H17Br2N5O2/c1-2-20-10-6-9(15)11(16)13(21(22)23)12(10)19-14(20)18-8-4-3-5-17-7-8/h6,8,17H,2-5,7H2,1H3,(H,18,19)/t8-/m0/s1	ZTJRWUVASWTOND-QMMMGPOBSA-N	319765	US10174013, Example 1AA	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2270							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319765	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319765&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144671	384223048							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625167	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNC(=O)C1	InChI=1S/C13H13Br2N5O3/c1-2-19-8-5-7(14)10(15)12(20(22)23)11(8)17-13(19)18-4-3-16-9(21)6-18/h5H,2-4,6H2,1H3,(H,16,21)	SAYBIVBDZZTHFR-UHFFFAOYSA-N	319755	US10174013, Example 22A::US10174013, Example 22AB::US10174013, Example 22J::US10174013, Example 22L::US10174013, Example 22R	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10090							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319755&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240547	384223043							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625168	NCCCNc1nc2c(c(Br)c(Br)cc2n1CC1CC1)[N+]([O-])=O	InChI=1S/C14H17Br2N5O2/c15-9-6-10-12(13(11(9)16)21(22)23)19-14(18-5-1-4-17)20(10)7-8-2-3-8/h6,8H,1-5,7,17H2,(H,18,19)	NLMNTGGEBQRLSF-UHFFFAOYSA-N	319767	US10174013, Example 1AB	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8930							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319767	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319767&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144631	384223049							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625169	CC(C)Cn1c(NC2CCCNCC2)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C17H23Br2N5O2/c1-10(2)9-23-13-8-12(18)14(19)16(24(25)26)15(13)22-17(23)21-11-4-3-6-20-7-5-11/h8,10-11,20H,3-7,9H2,1-2H3,(H,21,22)	ZTNVTLNODJVQHW-UHFFFAOYSA-N	319768	US10174013, Example 1AC	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1860							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319768	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319768&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528921	384223050							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625170	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1C	InChI=1S/C14H17Br2N5O2/c1-3-19-10-6-9(15)11(16)13(21(22)23)12(10)18-14(19)20-5-4-17-7-8(20)2/h6,8,17H,3-5,7H2,1-2H3	YUODAIKJHMEFDT-UHFFFAOYSA-N	319769	US10174013, Example 1AD	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1420							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319769&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528922	384223051							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625171	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCCCC(N)C1	InChI=1S/C15H19Br2N5O2/c1-2-21-11-7-10(16)12(17)14(22(23)24)13(11)19-15(21)20-6-4-3-5-9(18)8-20/h7,9H,2-6,8,18H2,1H3	CMFKAXYSXVSHIC-UHFFFAOYSA-N	319770	US10174013, Example 1AE	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 400							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528923	384223052							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625172	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCC[C@H](N)C1	InChI=1S/C14H17Br2N5O2/c1-2-20-10-6-9(15)11(16)13(21(22)23)12(10)18-14(20)19-5-3-4-8(17)7-19/h6,8H,2-5,7,17H2,1H3/t8-/m0/s1	MXLWHOOWSHGVEG-QMMMGPOBSA-N	319771	US10174013, Example 1AH	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4990							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319771	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319771&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			76286823	384223053							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625173	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCC[C@@H](N)C1	InChI=1S/C14H17Br2N5O2/c1-2-20-10-6-9(15)11(16)13(21(22)23)12(10)18-14(20)19-5-3-4-8(17)7-19/h6,8H,2-5,7,17H2,1H3/t8-/m1/s1	MXLWHOOWSHGVEG-MRVPVSSYSA-N	319772	US10174013, Example 1AI	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 440							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144711	384223054							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625174	CCn1c(NCCN)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C11H13Br2N5O2/c1-2-17-7-5-6(12)8(13)10(18(19)20)9(7)16-11(17)15-4-3-14/h5H,2-4,14H2,1H3,(H,15,16)	INYOGFGRCSKRGD-UHFFFAOYSA-N	319773	US10174013, Example 1AL	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2420							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144679	384223055							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625175	CCn1c(NCC2CCCN2)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C14H17Br2N5O2/c1-2-20-10-6-9(15)11(16)13(21(22)23)12(10)19-14(20)18-7-8-4-3-5-17-8/h6,8,17H,2-5,7H2,1H3,(H,18,19)	XCVVTLOSGICGTJ-UHFFFAOYSA-N	319774	US10174013, Example 1AM	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1460							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528926	384223056							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625176	CC(C)n1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCC[C@H](N)C1	InChI=1S/C15H19Br2N5O2/c1-8(2)21-11-6-10(16)12(17)14(22(23)24)13(11)19-15(21)20-5-3-4-9(18)7-20/h6,8-9H,3-5,7,18H2,1-2H3/t9-/m0/s1	VGSFXLOOCLYWJD-VIFPVBQESA-N	319775	US10174013, Example 1AP	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1820							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319775&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90242359	384223057							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625177	CC(C)n1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCOC(CN)C1	InChI=1S/C15H19Br2N5O3/c1-8(2)21-11-5-10(16)12(17)14(22(23)24)13(11)19-15(21)20-3-4-25-9(6-18)7-20/h5,8-9H,3-4,6-7,18H2,1-2H3	OMZJMALNALEQAD-UHFFFAOYSA-N	319776	US10174013, Example 1AQ	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1860							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319776&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528927	384223058							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625178	CC(C)n1c(NCC2CNCCO2)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C15H19Br2N5O3/c1-8(2)21-11-5-10(16)12(17)14(22(23)24)13(11)20-15(21)19-7-9-6-18-3-4-25-9/h5,8-9,18H,3-4,6-7H2,1-2H3,(H,19,20)	HGZIMTNVCYVDSN-UHFFFAOYSA-N	319777	US10174013, Example 1AR	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4170							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319777&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528928	384223059							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625179	CC(C)n1c(N[C@@H]2CCCNC2)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C15H19Br2N5O2/c1-8(2)21-11-6-10(16)12(17)14(22(23)24)13(11)20-15(21)19-9-4-3-5-18-7-9/h6,8-9,18H,3-5,7H2,1-2H3,(H,19,20)/t9-/m1/s1	KUCDREDVAAYLKN-SECBINFHSA-N	319778	US10174013, Example 1AS	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5770							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319778&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144735	384223060							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625180	CC(C)n1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNC[C@H]1C	InChI=1S/C15H19Br2N5O2/c1-8(2)21-11-6-10(16)12(17)14(22(23)24)13(11)19-15(21)20-5-4-18-7-9(20)3/h6,8-9,18H,4-5,7H2,1-3H3/t9-/m1/s1	RQEZRSGZDBMWMH-SECBINFHSA-N	319779	US10174013, Example 1AX	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1230							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319779&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135144713	384223061							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625181	CC(C)n1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CC[C@@H](N)C1	InChI=1S/C14H17Br2N5O2/c1-7(2)20-10-5-9(15)11(16)13(21(22)23)12(10)18-14(20)19-4-3-8(17)6-19/h5,7-8H,3-4,6,17H2,1-2H3/t8-/m1/s1	MQNJTZVRRKMREH-MRVPVSSYSA-N	319780	US10174013, Example 1AY	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3880							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319780&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118524593	384223062							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625182	CC(C)n1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CC[C@H](N)C1	InChI=1S/C14H17Br2N5O2/c1-7(2)20-10-5-9(15)11(16)13(21(22)23)12(10)18-14(20)19-4-3-8(17)6-19/h5,7-8H,3-4,6,17H2,1-2H3/t8-/m0/s1	MQNJTZVRRKMREH-QMMMGPOBSA-N	319781	US10174013, Example 1AZ	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1880							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319781	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319781&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90242456	384223063							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625183	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNC(=O)C1	InChI=1S/C13H13Br2N5O3/c1-2-19-8-5-7(14)10(15)12(20(22)23)11(8)17-13(19)18-4-3-16-9(21)6-18/h5H,2-4,6H2,1H3,(H,16,21)	SAYBIVBDZZTHFR-UHFFFAOYSA-N	319755	US10174013, Example 22A::US10174013, Example 22AB::US10174013, Example 22J::US10174013, Example 22L::US10174013, Example 22R	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11910							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319755&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240547	384223043							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625184	CC(C)n1c(nc2c(C#N)c(Br)c(Br)cc12)N1CC[C@@H](N)C1	InChI=1S/C15H17Br2N5/c1-8(2)22-12-5-11(16)13(17)10(6-18)14(12)20-15(22)21-4-3-9(19)7-21/h5,8-9H,3-4,7,19H2,1-2H3/t9-/m1/s1	XYXXTYQXZFVRCG-SECBINFHSA-N	319783	US10174013, Example 1BI	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5170							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319783	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319783&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240991	384223064							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625185	CC(C)n1c(N[C@H]2CCNC2)nc2c(c(Br)c(Br)cc12)[N+]([O-])=O	InChI=1S/C14H17Br2N5O2/c1-7(2)20-10-5-9(15)11(16)13(21(22)23)12(10)19-14(20)18-8-3-4-17-6-8/h5,7-8,17H,3-4,6H2,1-2H3,(H,18,19)/t8-/m0/s1	HXCPFYLZMOSGDW-QMMMGPOBSA-N	319784	US10174013, Example 1BD	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4340							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319784&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90242290	384223065							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625186	CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNC(=O)C1	InChI=1S/C13H13Br2N5O3/c1-2-19-8-5-7(14)10(15)12(20(22)23)11(8)17-13(19)18-4-3-16-9(21)6-18/h5H,2-4,6H2,1H3,(H,16,21)	SAYBIVBDZZTHFR-UHFFFAOYSA-N	319755	US10174013, Example 22A::US10174013, Example 22AB::US10174013, Example 22J::US10174013, Example 22L::US10174013, Example 22R	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2020							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319755&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			90240547	384223043							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
625187	CC(C)n1c(nc2c(C#N)c(Br)c(Br)cc12)N1CCOC(CN)C1	InChI=1S/C16H19Br2N5O/c1-9(2)23-13-5-12(17)14(18)11(7-20)15(13)21-16(23)22-3-4-24-10(6-19)8-22/h5,9-10H,3-4,6,8,19H2,1-2H3	CKDGYIZZEFNIIK-UHFFFAOYSA-N	319786	US10174013, Example 1BM	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 740							US Patent		10.7270/Q2QR5069		aid1796640	US10174013	Czardybon, W; Brzozka, K; Galezowski, M; Windak, R; Milik, M; Zawadzka, M; Guzik, P; Wincza, E; Prokop, M; Wiklik, K; Sabiniarz, A; Cholody, WM; Horvath, R; Rzymski, T	1/8/2019	5/15/2019	Selvita S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=319786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=319786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118528939	384223066							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659318	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(F)cncc1F	InChI=1S/C24H19F3N4O2/c25-18-4-1-14(24(32)22-19(26)11-28-12-20(22)27)9-17(18)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	UTPQVJZOHIQDGB-UHFFFAOYSA-N	315505	(3,5-Difluoro-pyridin-4- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.50 (s, 2H), 7.65-7.60 (m, 2H), 7.55-7.48 (m, 2H), 7.45-7.40 (m, 1H), 7.20 (d, J = 2.1, 1H), 6.62 (d, J = 4.6, 1H), 6.23 (d, J = 4.6, 1H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US10172859, Example 1::US11065253, Example 1::US9732094, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315505&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696291	383542264							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659320	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(F)c1Cl	InChI=1S/C24H19ClF2N4O2/c25-22-18(11-28-12-20(22)27)24(32)14-1-4-19(26)17(9-14)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	KJBYMUZTLUOOTH-UHFFFAOYSA-N	315511	(4-Chloro-5-fluoro- pyridin-3-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.70 (s, 1H), 8.66 (s, 1H), 7.64-7.59 (m, 2H), 7.55- 7.48 (m, 2H), 7.44-7.39 (m, 1H), 7.20 (d, J = 2.2, 1H), 6.56 (d, J = 4.4, 1H), 6.12 (d, J = 4.5, 1H), 3.81- 3.74 (m, 4H), 3.47-3.40 (m, 4H)::US10172859, Example 2::US11065253, Example 2::US9732094, Example 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315511&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86294562	383542270							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659322	COc1ccnnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-21-4-5-29-30-23(21)24(32)16-11-17(19(26)12-18(16)25)22-15-3-2-14(10-20(15)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	LMRHWYRLOVDZKO-UHFFFAOYSA-N	315513	US10172859, Example 3::US11065253, Example 3::US9732094, Example 3::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (4-methoxy-pyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H), 8.96 (d, J = 6.0, 1H), 8.04-8.01 (m, 1H), 7.65- 7.60 (m, 2H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.32 (d, J = 6.0, 1H), 7.22 (d, J = 2.5, 1H), 6.46 (d, J = 6.2, 1H), 6.39 (d, J = 6.3, 1H), 3.96 (s, 3H), 3.81-3.75 (m, 4H), 3.50-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315513&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954887	383542272							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659324	COc1nnccc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-16(4-5-29-30-24)23(32)17-11-18(20(26)12-19(17)25)22-15-3-2-14(10-21(15)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	NYDMCEVKGDKDIY-UHFFFAOYSA-N	315576	US10172859, Example 4::US11065253, Example 4::US9732094, Example 4::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s, 1H), 8.88 (d, J = 4.7, 1H), 7.71 (d, J = 9.5, 1H), 7.59 (dd, J = 4.7, 0.9, 1H), 7.54 (d, J = 7.6, 1H), 7.52-7.50 (m, 2H), 7.21-7.17 (m, 1H), 6.46 (d, J = 5.1, 1H), 6.15 (d, J = 5.2, 1H), 4.01 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315576&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966363	383542335							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659326	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncc[nH]c1=O			315577	3-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-1H- pyrazin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.69-7.59 (m, 2H), 7.56-7.50 (m, 2H), 7.39- 7.28 (m, 3H), 7.20 (d, J = 2.1, 1H), 6.00 (s, 1H), 5.87-5.75 (m, 1H), 3.81-3.74 (m, 4H), 3.44 (t, J = 5.0, 4H)::US10172859, Example 5::US11065253, Example 5::US9732094, Example 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315577&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106835	383542336							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659328	COc1nnc(Cl)cc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20Cl2FN5O3/c1-34-24-17(10-21(26)30-31-24)23(33)15-9-16(19(27)11-18(15)25)22-14-3-2-13(8-20(14)28-12-29-22)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	ZGAJFLBXEVLQHV-UHFFFAOYSA-N	315579	US10172859, Example 6::US11065253, Example 6::US9732094, Example 6::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-chloro-5-methoxy- pyridazin-3-yl) methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s, 1H), 7.75 (d, J = 1.0, 1H), 7.72 (d, J = 9.5, 1H), 7.56 (d, J = 7.6, 1H), 7.51 (dd, J = 9.5, 2.5, 1H), 7.47 (dd, J = 9.4, 2.9, 1H), 7.19 (d, J = 2.4, 1H), 6.59 (d, J = 5.0, 1H), 6.13-6.10 (m, 1H), 3.98 (s, 3H), 3.80-3.74 (m, 4H), 3.48-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315579&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966366	383542338							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659330	COc1cc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Cl)nn1	InChI=1S/C24H21ClFN5O3/c1-33-21-12-18(24(25)30-29-21)23(32)14-2-5-19(26)17(10-14)22-16-4-3-15(11-20(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	KSMYOVIQSVHQKI-UHFFFAOYSA-N	315580	(3-Chloro-6-methoxy- pyridazin-4-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.62-7.57 (m, 2H), 7.55-7.47 (m, 3H), 7.43- 7.39 (m, 1H), 7.20 (d, J = 2.4, 1H), 6.58 (d, J = 4.5, 1H), 5.88 (d, J = 4.4, 1H), 4.04 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US10172859, Example 7::US11065253, Example 7::US9732094, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315580&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86294560	383542339							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659332	COc1cc(Cl)nnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20Cl2FN5O3/c1-34-20-11-21(26)30-31-23(20)24(33)15-9-16(18(27)10-17(15)25)22-14-3-2-13(8-19(14)28-12-29-22)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	URDZKJLOZSFJOE-UHFFFAOYSA-N	315581	US10172859, Example 8::US11065253, Example 8::US9732094, Example 8::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-chloro-4-methoxy- pyridazin-3-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H), 8.01-7.99 (m, 1H), 7.65-7.59 (m, 3H), 7.56 (dd, J = 9.5, 2.5, 1H), 7.22 (d, J = 2.5, 1H), 6.52 (d, J = 6.2, 1H), 6.39 (d, J = 6.2, 1H), 4.02 (s, 3H), 3.80-3.76 (m, 4H), 3.48-3.44 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315581&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954988	383542340							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659334	COc1nnc(Cl)cc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-18(12-21(25)29-30-24)23(32)14-2-5-19(26)17(10-14)22-16-4-3-15(11-20(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	PBEWANFAIGVJRA-UHFFFAOYSA-N	315582	(6-Chloro-5-methoxy- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.88 (d, J = 1.0, 1H), 7.63-7.58 (m, 2H), 7.55- 7.47 (m, 2H), 7.42-7.35 (m, 1H), 7.20 (d, J = 2.3, 1H), 6.46 (d, J = 4.3, 1H), 5.85-5.82 (m, 1H), 4.00 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 286::US10172859, Example 9::US11065253, Example 286::US9732094, Example 286	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315582&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954747	383542341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659336	COc1cc(Cl)nnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-20-12-21(25)29-30-23(20)24(32)14-2-5-18(26)17(10-14)22-16-4-3-15(11-19(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	LAPIHKKQBZORLI-UHFFFAOYSA-N	315583	(6-Chloro-4-methoxy- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.64-7.60 (m, 2H), 7.53-7.51 (m, 3H), 7.40- 7.35 (m, 1H), 7.21-7.19 (m, 1H), 6.29 (d, J = 5.3, 1H), 6.18 (d, J = 4.3, 1H), 3.93 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)::US10172859, Example 10::US11065253, Example 10::US9732094, Example 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315583&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86294564	383542342							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659338	COc1nnccc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-18(6-7-28-29-24)23(31)15-2-5-20(25)19(12-15)22-17-4-3-16(13-21(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	SLGPVTYHXWXXSC-UHFFFAOYSA-N	315584	US10172859, Example 11::US10172859, Example 12::US10172859, Example 19::US11065253, Example 19::US9732094, Example 19::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966365	383542343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659340	COc1nnccc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-18(6-7-28-29-24)23(31)15-2-5-20(25)19(12-15)22-17-4-3-16(13-21(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	SLGPVTYHXWXXSC-UHFFFAOYSA-N	315584	US10172859, Example 11::US10172859, Example 12::US10172859, Example 19::US11065253, Example 19::US9732094, Example 19::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966365	383542343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659342	CC(C)(C)Oc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H28FN5O3/c1-27(2,3)36-26-24(29-8-9-30-26)25(34)17-4-7-21(28)20(14-17)23-19-6-5-18(15-22(19)31-16-32-23)33-10-12-35-13-11-33/h4-9,14-16,25,34H,10-13H2,1-3H3	IHJXGTTTXOYFEL-UHFFFAOYSA-N	315586	(3-tert-Butoxy-pyrazin- 2-yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.14 (d, J = 2.7, 1H), 8.08 (d, J = 2.7, 1H), 7.63- 7.56 (m, 2H), 7.54-7.47 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 5.97 (d, J = 6.0, 1H), 5.91 (d, J = 6.1, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m, 4H), 1.47 (s, 9H)::US10172859, Example 13::US11065253, Example 13::US9732094, Example 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315586&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954800	383542344							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659344	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1N1CCCC1	InChI=1S/C27H27FN6O2/c28-22-6-3-18(26(35)25-27(30-8-7-29-25)34-9-1-2-10-34)15-21(22)24-20-5-4-19(16-23(20)31-17-32-24)33-11-13-36-14-12-33/h3-8,15-17,26,35H,1-2,9-14H2	GPLAQASQYVIJRV-UHFFFAOYSA-N	315587	US10172859, Example 14::US11065253, Example 14::US9732094, Example 14::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-pyrrolidin-1-yl- pyrazin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.99 (d, J = 2.4, 1H), 7.80 (d, J = 2.5, 1H), 7.58- 7.52 (m, 4H), 7.38-7.32 (m, 1H), 7.21-7.17 (m, 1H), 6.18-6.13 (m, 1H), 6.09-6.01 (m, 1H), 3.78 (t, J = 4.9, 4H), 3.68-3.56 (m, 4H), 3.44 (t, J = 4.9, 4H), 1.96-1.81 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315587&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954734	383542345							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659346	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)15-2-5-19(25)18(12-15)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QHNQVNYRYQEKGM-UHFFFAOYSA-N	315588	US10172859, Example 15::US10172859, Example 16::US10172859, Example 38::US11065253, Example 38::US9732094, Example 38::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methoxy-pyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292071	383542346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659348	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)15-2-5-19(25)18(12-15)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QHNQVNYRYQEKGM-UHFFFAOYSA-N	315588	US10172859, Example 15::US10172859, Example 16::US10172859, Example 38::US11065253, Example 38::US9732094, Example 38::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methoxy-pyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292071	383542346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659350	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(Cl)cncc1Cl	InChI=1S/C24H19Cl2FN4O2/c25-18-11-28-12-19(26)22(18)24(32)14-1-4-20(27)17(9-14)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	JUJIBZUQPZFDCW-UHFFFAOYSA-N	315591	(3,5-Dichloro-pyridin-4- yl)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.62 (s, 2H), 7.58-7.48 (m, 4H), 7.43-7.37 (m, 1H), 7.19 (d, J = 2.2, 1H), 6.70-6.65 (m, 1H), 6.52 (d, J = 4.7, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H)::US10172859, Example 17::US11065253, Example 17::US9732094, Example 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315591&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954735	383542348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659352	COc1ccnnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-21-6-7-28-29-23(21)24(31)15-2-5-19(25)18(12-15)22-17-4-3-16(13-20(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	CYGVNIZYJOHEKW-UHFFFAOYSA-N	315592	US10172859, Example 18::US11065253, Example 18::US9732094, Example 18::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (4-methoxy-pyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11-9.08 (m, 1H), 8.99-8.95 (m, 1H), 7.65-7.59 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.34 (m, 1H), 7.27 (d, J = 5.9, 1H), 7.22-7.18 (m, 1H), 6.24-6.18 (m, 2H), 3.88 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315592&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954974	383542349							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659354	COc1nnccc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-18(6-7-28-29-24)23(31)15-2-5-20(25)19(12-15)22-17-4-3-16(13-21(17)26-14-27-22)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	SLGPVTYHXWXXSC-UHFFFAOYSA-N	315584	US10172859, Example 11::US10172859, Example 12::US10172859, Example 19::US11065253, Example 19::US9732094, Example 19::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyridazin-3- yl)methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315584&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966365	383542343							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659356	OC(c1ccc2nccn2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(25(34)21-3-4-23-28-5-6-33(23)31-21)12-17(19)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SBDSJWIXIDMXMK-UHFFFAOYSA-N	315594	US10172859, Example 20::US10172859, Example 21::US10172859, Example 51::US11065253, Example 51::US9732094, Example 51::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- itnidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696725	383542350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659358	OC(c1ccc2nccn2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(25(34)21-3-4-23-28-5-6-33(23)31-21)12-17(19)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SBDSJWIXIDMXMK-UHFFFAOYSA-N	315594	US10172859, Example 20::US10172859, Example 21::US10172859, Example 51::US11065253, Example 51::US9732094, Example 51::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- itnidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696725	383542350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659360	COc1cnc(Cl)c(c1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-33-17-12-20(25(26)28-13-17)24(32)15-2-5-21(27)19(10-15)23-18-4-3-16(11-22(18)29-14-30-23)31-6-8-34-9-7-31/h2-5,10-14,24,32H,6-9H2,1H3	WXRISZAPVAJOEF-UHFFFAOYSA-N	315596	(2-Chloro-5-methoxy- pyridin-3-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.28 (d, J = 2.6, 1H), 7.62-7.55 (m, 3H), 7.55- 7.49 (m, 2H), 7.41-7.32 (m, 1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.03 (d, J = 6.1, 1H), 3.85 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US10172859, Example 22::US11065253, Example 22::US9732094, Example 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315596&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291666	383542351							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659362	OC(c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C21H17ClFN5O2S/c22-21-18(24-3-4-25-21)19(29)12-1-2-14(23)13(9-12)17-20-15(26-11-27-17)10-16(31-20)28-5-7-30-8-6-28/h1-4,9-11,19,29H,5-8H2	SDVPZFAXJNURBD-UHFFFAOYSA-N	315597	(3-Chloro-pyrazin-2-yl)- [4-fluoro-3-(6- morpholin-4-yl-thieno- [3,2-d}pyrimidin-4-yl)- phenyl]methanol (Ena 1)identical to enantiomer (24)::US10172859, Example 23::US10172859, Example 24::US10172859, Example 37::US11065253, Example 37::US9732094, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292070	383542352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659364	OC(c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C21H17ClFN5O2S/c22-21-18(24-3-4-25-21)19(29)12-1-2-14(23)13(9-12)17-20-15(26-11-27-17)10-16(31-20)28-5-7-30-8-6-28/h1-4,9-11,19,29H,5-8H2	SDVPZFAXJNURBD-UHFFFAOYSA-N	315597	(3-Chloro-pyrazin-2-yl)- [4-fluoro-3-(6- morpholin-4-yl-thieno- [3,2-d}pyrimidin-4-yl)- phenyl]methanol (Ena 1)identical to enantiomer (24)::US10172859, Example 23::US10172859, Example 24::US10172859, Example 37::US11065253, Example 37::US9732094, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292070	383542352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659366	COc1ncc(Cl)nc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(30-20(25)12-27-24)23(32)14-2-5-18(26)17(10-14)21-16-4-3-15(11-19(16)28-13-29-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YRICZHMWIWNYIX-UHFFFAOYSA-N	315599	(6-Chloro-3-methoxy- pyrazin-2-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.30 (s, 1H), 7.65-7.60 (m, 2H), 7.57-7.51 (m, 2H), 7.43-7.36 (m, 1H), 7.22-7.19 (m, 1H), 6.18 (s, 1H), 6.06-6.02 (m, 1H), 3.94 (s, 3H), 3.81- 3.75 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 25::US11065253, Example 25::US9732094, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315599&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291869	383542353							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659368	COc1cnc(Cl)c(n1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-20-12-27-24(25)22(30-20)23(32)14-2-5-18(26)17(10-14)21-16-4-3-15(11-19(16)28-13-29-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MFNKUHDJBOVSQS-UHFFFAOYSA-N	315600	(3-Chloro-6-methoxy- pyrazin-2-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.11 (s, 1H), 7.73-7.68 (m, 2H), 7.54-7.50 (m, 2H), 7.44-7.38 (m, 1H), 7.21-7.19 (m, 1H), 6.31 (d, J = 5.7, 1H), 6.11 (d, J = 5.8, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 26::US11065253, Example 26::US9732094, Example 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315600&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291868	383542354							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659370	O[C@H](c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H19ClFN5O2/c24-23-21(26-5-6-27-23)22(31)14-1-4-18(25)17(11-14)20-16-3-2-15(12-19(16)28-13-29-20)30-7-9-32-10-8-30/h1-6,11-13,22,31H,7-10H2/t22-/m1/s1	SOXWGEFOMMQSBW-JOCHJYFZSA-N	335518	(R)-(3-Chloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol::US11065253, Example 27::US9732094, Example 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335518&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291668	384987677							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659372	O[C@@H](c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H19ClFN5O2/c24-23-21(26-5-6-27-23)22(31)14-1-4-18(25)17(11-14)20-16-3-2-15(12-19(16)28-13-29-20)30-7-9-32-10-8-30/h1-6,11-13,22,31H,7-10H2/t22-/m0/s1	SOXWGEFOMMQSBW-QFIPXVFZSA-N	335519	(S)-(3-Chloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol::US11065253, Example 28::US9732094, Example 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335519&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954846	384987678							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659374	OC(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-12-19(25)17(11-16(18)23(31)20-2-1-5-28-29-20)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	ZYGYHTYPQAHIIL-UHFFFAOYSA-N	315603	US10172859, Example 29::US10172859, Example 30::US10172859, Example 47::US11065253, Example 47::US9732094, Example 47::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.7, 1H), 9.11 (s, 1H), 7.88 (d, J = 7.7, 1H), 7.80 (dd, J = 8.6, 1.7, 1H), 7.72-7.66 (m, 2H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (d, J = 5.0, 1H), 6.32 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292263	383542356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659376	OC(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-12-19(25)17(11-16(18)23(31)20-2-1-5-28-29-20)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	ZYGYHTYPQAHIIL-UHFFFAOYSA-N	315603	US10172859, Example 29::US10172859, Example 30::US10172859, Example 47::US11065253, Example 47::US9732094, Example 47::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.7, 1H), 9.11 (s, 1H), 7.88 (d, J = 7.7, 1H), 7.80 (dd, J = 8.6, 1.7, 1H), 7.72-7.66 (m, 2H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (d, J = 5.0, 1H), 6.32 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292263	383542356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659378	COc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Cl)c1	InChI=1S/C25H22ClFN4O3/c1-33-17-12-20(26)24(28-13-17)25(32)15-2-5-21(27)19(10-15)23-18-4-3-16(11-22(18)29-14-30-23)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	WUHDWUZGBYYHTQ-UHFFFAOYSA-N	315605	(3-Chloro-5-methoxy- pyridin-2-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.28 (d, J = 2.6, 1H), 7.62-7.55 (m, 3H), 7 55- 7.49 (m, 2H), 7.41-7.32 (m, 1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.03 (d, J = 6.1, 1H), 3.85 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US10172859, Example 31::US11065253, Example 31::US9732094, Example 31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315605&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291873	383542357							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659380	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC1COC1	InChI=1S/C26H24FN5O4/c27-21-4-1-16(25(33)24-26(29-6-5-28-24)36-18-13-35-14-18)11-20(21)23-19-3-2-17(12-22(19)30-15-31-23)32-7-9-34-10-8-32/h1-6,11-12,15,18,25,33H,7-10,13-14H2	GEZJANXQGHIRIL-UHFFFAOYSA-N	315606	US10172859, Example 32::US11065253, Example 32::US9732094, Example 32::[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- [3-(oxetan-3-yloxy)- pyrazin-2-yl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.24 (d, J = 2.7, 1H), 8.09 (d, J = 2.8, 1H), 7.71- 7.64 (m, 2H), 7.54-7.51 (m, 2H), 7.42-7.36 (m, 1H), 7.22-7.19 (m, 1H), 6.15-6.11 (m, 2H), 5.63- 5.58 (m, 1H), 4.88-4.83 (m, 2H), 4.58-4.52 (m, 2H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315606&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954854	383542358							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659382	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cnccn1	InChI=1S/C23H20FN5O2/c24-19-4-1-15(23(30)21-13-25-5-6-26-21)11-18(19)22-17-3-2-16(12-20(17)27-14-28-22)29-7-9-31-10-8-29/h1-6,11-14,23,30H,7-10H2	ASBXJSXOJUIGQQ-UHFFFAOYSA-N	315607	US10172859, Example 33::US11065253, Example 33::US9732094, Example 33::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyrazin-2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.89 (d, J = 1.5, 1H), 8.59-8.53 (m, 2H), 7.71- 7.65 (m, 2H), 7.57-7.50 (m, 2H), 7.44-7.37 (m, 1H), 7.21-7.19 (m, 1H), 5.94 (s, 1H), 3.81-3.75 (m, 4H), 3.49-3.44 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315607&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954758	383542359							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659384	OC(c1cnccn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-11-19(25)17(10-16(18)23(31)21-12-26-3-4-27-21)22-15-2-1-14(9-20(15)28-13-29-22)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	VXJBPIDEFGKNNZ-UHFFFAOYSA-N	315608	US10172859, Example 34::US11065253, Example 34::US9732094, Example 34::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyrazin-2-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.86 (d, J = 1.3, 1H), 8.58-8.55 (m, 2H), 7.88 (d, J = 7.7, 1H), 7.66 (d, J = 9.5, 1H), 7.60-7.52 (m, 2H), 7.21 (d, J = 2.3, 1H), 6.62 (d, J = 4.9, 1H), 6.19 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.49-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315608&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954905	383542360							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659386	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nc(Cl)cnc1Cl	InChI=1S/C23H18Cl2FN5O2/c24-19-11-27-23(25)21(30-19)22(32)13-1-4-17(26)16(9-13)20-15-3-2-14(10-18(15)28-12-29-20)31-5-7-33-8-6-31/h1-4,9-12,22,32H,5-8H2	XHOQZGNYQBPNLL-UHFFFAOYSA-N	315609	(3,6-Dichloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.63 (s, 1H), 7.68-7.64 (m, 2H), 7.55-7.51 (m, 2H), 7.45-7.40 (m, 1H), 7.20 (d, J = 2.1, 1H), 6.51 (d, J = 5.5, 1H), 6.18 (d, J = 5.5, 1H), 3.81-3.75 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 35::US11065253, Example 35::US9732094, Example 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315609&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291872	383542361							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659388	OC(c1ccnnc1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-19-11-20(25)18(10-17(19)23(31)14-3-4-28-29-12-14)22-16-2-1-15(9-21(16)26-13-27-22)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	USXKUTZDUWEZBD-UHFFFAOYSA-N	315610	US10172859, Example 36::US11065253, Example 36::US9732094, Example 36::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-4-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.27-9.25 (m, 1H), 9.19 (dd, J = 5.3, 1.2, 1H), 9.11 (s, 1H), 7.89 (d, J = 7.6, 1H), 7.72 (d, J = 9.5, 1H), 7.62- 7.56 (m, 2H), 7.53 (dd, J = 9.4, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.72 (s, 1H), 6.13 (s, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315610&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86291871	383542362							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659390	OC(c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C21H17ClFN5O2S/c22-21-18(24-3-4-25-21)19(29)12-1-2-14(23)13(9-12)17-20-15(26-11-27-17)10-16(31-20)28-5-7-30-8-6-28/h1-4,9-11,19,29H,5-8H2	SDVPZFAXJNURBD-UHFFFAOYSA-N	315597	(3-Chloro-pyrazin-2-yl)- [4-fluoro-3-(6- morpholin-4-yl-thieno- [3,2-d}pyrimidin-4-yl)- phenyl]methanol (Ena 1)identical to enantiomer (24)::US10172859, Example 23::US10172859, Example 24::US10172859, Example 37::US11065253, Example 37::US9732094, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292070	383542352							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659392	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)15-2-5-19(25)18(12-15)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QHNQVNYRYQEKGM-UHFFFAOYSA-N	315588	US10172859, Example 15::US10172859, Example 16::US10172859, Example 38::US11065253, Example 38::US9732094, Example 38::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methoxy-pyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292071	383542346							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659394	OC(c1ccn2nccc2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-4-6-33-23(31-21)3-5-30-33)24-16-2-1-15(11-22(16)28-14-29-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	DRBCELNQNRVAMX-UHFFFAOYSA-N	315613	US10172859, Example 39::US11065253, Example 39::US9732094, Example 39::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyrazolo[1,5-a]- pyrimidin-5-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 9.08 (dd, J = 7.2, 0.9, 1H), 8.19 (d, J = 2.4, 1H), 7.87 (d, J = 7.7, 1H), 7.69 (d, J = 9.5, 1H), 7.58 (dd, J = 9.4, 3.2, 1H), 7.52 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.5, 1H), 7.17 (d, J = 7.3, 1H), 6.71 (d, J = 5.0, 1H), 6.67 (dd, J = 2.3, 0.9, 1H), 6.11 (d, J = 4.8, 1H), 3.82- 3.74 (m, 4H), 3.49-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315613&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292072	383542363							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659396	COc1nnc(C(O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)c2ccncc12	InChI=1S/C27H22ClFN6O3/c1-37-27-20-13-30-5-4-16(20)25(33-34-27)26(36)18-11-19(22(29)12-21(18)28)24-17-3-2-15(10-23(17)31-14-32-24)35-6-8-38-9-7-35/h2-5,10-14,26,36H,6-9H2,1H3	OYABTHYQTFVSLR-UHFFFAOYSA-N	315614	US10172859, Example 40::US11065253, Example 40::US9732094, Example 40::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (4-methoxypyrido- [3,4-d}pyridazin-1-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.97 (s, 1H), 9.15 (s, 1H), 9.11 (d, J = 5.5, 1H), 8.10-8.02 (m, 2H), 7.73-7.62 (m, 2H), 7.57 (dd, J = 9.5, 2.5, 1H), 7.23 (d, J = 2.4, 1H), 6.95-6.87 (m, 2H), 4.18 (s, 3H), 3.84-3.74 (m, 4H), 3.52-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315614&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954879	383542364							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659398	OC(c1ccc(Cl)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H18Cl2FN5O2/c24-17-11-18(26)16(10-15(17)23(32)19-3-4-21(25)30-29-19)22-14-2-1-13(9-20(14)27-12-28-22)31-5-7-33-8-6-31/h1-4,9-12,23,32H,5-8H2	SXLLMNZBCYWXBH-UHFFFAOYSA-N	315615	US10172859, Example 41::US11065253, Example 41::US9732094, Example 41::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-chloro-pyridazin-3- yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 7.92-7.90 (m, 2H), 7.90-7.87 (m, 1H), 7.69 (d, J = 9.5, 1H), 7.58 (dd, J = 9.4, 3.2, 1H), 7.53 (dd, J = 9.5, 2.4, 1H), 7.20 (d, J = 2.3, 1H), 6.86 (d, J = 5.0, 1H), 6.32 (d, J = 4.5, 1H), 3.81-3.74 (m, 4H), 3.48- 3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315615&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292073	383542365							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659400	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C24H20ClFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	IKPAUHLVUSUQBQ-UHFFFAOYSA-N	315616	(3-Chloro-pyridin-2-yl)- [4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.56 (dd, J = 4.6, 1.4, 1H), 7.92 (dd, J = 8.1, 1.4, 1H), 7.64-7.59 (m, 2H), 7.54-7.49 (m, 2H), 7.40- 7.34 (m, 2H), 7.22-7.17 (m, 1H), 6.21 (s, 1H), 6.18-6.09 (m, 1H), 3.81-3.73 (m, 4H), 3.48- 3.40 (m, 4H)::US10172859, Example 42::US10172859, Example 465::US10172859, Example 466::US11065253, Example 42::US9732094, Example 466	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292074	383542366							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659402	CNC(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-28-25(35)21-5-4-20(31-32-21)24(34)16-11-17(19(27)12-18(16)26)23-15-3-2-14(10-22(15)29-13-30-23)33-6-8-36-9-7-33/h2-5,10-13,24,34H,6-9H2,1H3,(H,28,35)	GHVIVLAZMTUKIH-UHFFFAOYSA-N	315617	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid methylamide1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (q, J = 4.7, 1H), 9.11 (s, 1H), 8.19 (d, J = 8.7, 1H), 7.99 (d, J = 8.7, 1H), 7.87 (d, J = 7.7, 1H), 7.69 (d, J = 9.5, 1H), 7.58-7.51 (m, 2H), 7.22-7.19 (m, 1H), 6.84 (s, 1H), 6.42 (s, 1H), 3.80-3.76 (m, 4H), 3.47- 3.42 (m, 4H), 2.85 (d, J = 4.7, 3H)::US10172859, Example 43::US11065253, Example 43::US9732094, Example 43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315617&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954990	383542367							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659404	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	TYZMCDRHMQABIJ-UHFFFAOYSA-N	315618	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- methyl-2H-pyridazin-3- one (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 7.93 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.61- 7.52 (m, 2H), 7.48 (d, J = 9.6, 1H), 7.21 (d, J = 2.4, 1H), 6.93 (d, J = 9.6, 1H), 6.60 (d, J = 4.8, 1H), 5.89 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.59 (s, 3H), 3.48-3.43 (m, 4H)::US10172859, Example 44::US10172859, Example 45::US10172859, Example 59::US11065253, Example 59::US9732094, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954795	383542368							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659406	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	TYZMCDRHMQABIJ-UHFFFAOYSA-N	315618	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- methyl-2H-pyridazin-3- one (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 7.93 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.61- 7.52 (m, 2H), 7.48 (d, J = 9.6, 1H), 7.21 (d, J = 2.4, 1H), 6.93 (d, J = 9.6, 1H), 6.60 (d, J = 4.8, 1H), 5.89 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.59 (s, 3H), 3.48-3.43 (m, 4H)::US10172859, Example 44::US10172859, Example 45::US10172859, Example 59::US11065253, Example 59::US9732094, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954795	383542368							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659408	Cc1cnnc(c1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O2/c1-14-8-22(30-29-12-14)24(32)17-10-18(20(26)11-19(17)25)23-16-3-2-15(9-21(16)27-13-28-23)31-4-6-33-7-5-31/h2-3,8-13,24,32H,4-7H2,1H3	IWIZEUGGMFCIBN-UHFFFAOYSA-N	315620	US10172859, Example 46::US11065253, Example 46::US9732094, Example 46::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 9.00 (d, J = 2.0, 1H), 7.87 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H), 7.63-7.61 (m, 1H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.65 (d, J = 4.9, 1H), 6.28 (d, J = 4.9, 1H), 3.80- 3.75 (m, 4H), 3.48-3.42 (m, 4H), 2.32 (s, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315620&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954944	383542369							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659410	OC(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19ClFN5O2/c24-18-12-19(25)17(11-16(18)23(31)20-2-1-5-28-29-20)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	ZYGYHTYPQAHIIL-UHFFFAOYSA-N	315603	US10172859, Example 29::US10172859, Example 30::US10172859, Example 47::US11065253, Example 47::US9732094, Example 47::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.7, 1H), 9.11 (s, 1H), 7.88 (d, J = 7.7, 1H), 7.80 (dd, J = 8.6, 1.7, 1H), 7.72-7.66 (m, 2H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (d, J = 5.0, 1H), 6.32 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292263	383542356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659412	OC(c1cccnn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19F2N5O2/c24-18-12-19(25)17(23(31)20-2-1-5-28-29-20)11-16(18)22-15-4-3-14(10-21(15)26-13-27-22)30-6-8-32-9-7-30/h1-5,10-13,23,31H,6-9H2	DMVVLKYGVRDAES-UHFFFAOYSA-N	315622	US10172859, Example 48::US11065253, Example 48::US9732094, Example 48::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd, J = 4.9, 1.6, 1H), 9.10 (s, 1H), 7.86 (dd, J = 8.5, 1.6, 1H), 7.81 (t, J = 8.1, 1H), 7.72 (dd, J = 8.5, 4.9, 1H), 7.58-7.51 (m, 2H), 7.46 (t, J = 10.1, 1H), 7.20 (d, J = 2.3, 1H), 6.66 (d, J = 4.9, 1H), 6.26 (d, J = 4.9, 1H), 3.81-3.75 (m, 4H), 3.45 (t, J = 4.9, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315622&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954875	383542370							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659414	OC(c1ccc(Cl)nn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H18ClF2N5O2/c24-21-4-3-19(29-30-21)23(32)16-10-15(17(25)11-18(16)26)22-14-2-1-13(9-20(14)27-12-28-22)31-5-7-33-8-6-31/h1-4,9-12,23,32H,5-8H2	RYTVQFQGZIKYTM-UHFFFAOYSA-N	315623	(6-Chloro-pyridazin-3- yl)-[2,4-difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.98-7.91 (m, 2H), 7.82 (t, J = 8.1, 1H), 7.58-7.51 (m, 2H), 7.47 (t, J = 10.1, 1H), 7.20 (d, J = 2.3, 1H), 6.78 (d, J = 4.9, 1H) 6.26 (d, J = 4.6, 1H), 3.82- 3.74 (m, 4H), 3.48-3.41 (m, 4H).::US10172859, Example 49::US11065253, Example 49::US9732094, Example 49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315623&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954910	383542371							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659416	CN(C)C(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H24ClFN6O3/c1-33(2)26(36)22-6-5-21(31-32-22)25(35)17-12-18(20(28)13-19(17)27)24-16-4-3-15(11-23(16)29-14-30-24)34-7-9-37-10-8-34/h3-6,11-14,25,35H,7-10H2,1-2H3	YUXWTDZVOLHXGC-UHFFFAOYSA-N	315624	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid dimethylamide1H NMR (500 MHz, chloroform-d) ppm = 9.15 (s, 1H), 7.85 (d, J = 8.7, 1H), 7.79 (d, J = 7.4, 1H), 7.65 (d, J = 8.7, 1H), 7.56 (dd, J = 9.3, 3.3, 1H), 7.36 (d, J = 9.0, 1H), 7.27 (d, J = 2.5, 1H), 7.22 (d, J = 2.5, 1H), 6.54 (s, 1H), 4.99 (s, 1H), 3.92-3.87 (m, 4H), 3.46-3.42 (m, 4H), 3.22 (s, 3H), 3.19 (s, 3H)::US10172859, Example 50::US11065253, Example 50::US9732094, Example 50	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315624&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954844	383542372							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659418	OC(c1ccc2nccn2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(25(34)21-3-4-23-28-5-6-33(23)31-21)12-17(19)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SBDSJWIXIDMXMK-UHFFFAOYSA-N	315594	US10172859, Example 20::US10172859, Example 21::US10172859, Example 51::US11065253, Example 51::US9732094, Example 51::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- itnidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696725	383542350							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659420	COc1cnc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-13-26-21(12-27-22)24(31)15-2-5-19(25)18(10-15)23-17-4-3-16(11-20(17)28-14-29-23)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WYEVURVICOACEU-UHFFFAOYSA-N	315626	US10172859, Example 52::US10172859, Example 53::US10172859, Example 60::US11065253, Example 60::US9732094, Example 60::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyrazin-2- yl)methanol (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.39-8.38 (m, 1H), 8.23 (d, J = 1.3, 1H), 7.66- 7.61 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 6.30 (d, J = 4.4, 1H), 5.88 (d, J = 4.4, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954847	383542373							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659422	COc1cnc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-13-26-21(12-27-22)24(31)15-2-5-19(25)18(10-15)23-17-4-3-16(11-20(17)28-14-29-23)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WYEVURVICOACEU-UHFFFAOYSA-N	315626	US10172859, Example 52::US10172859, Example 53::US10172859, Example 60::US11065253, Example 60::US9732094, Example 60::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyrazin-2- yl)methanol (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.39-8.38 (m, 1H), 8.23 (d, J = 1.3, 1H), 7.66- 7.61 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 6.30 (d, J = 4.4, 1H), 5.88 (d, J = 4.4, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954847	383542373							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659424	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H19ClFN5O2/c24-23-21(26-5-6-27-23)22(31)14-1-4-18(25)17(11-14)20-16-3-2-15(12-19(16)28-13-29-20)30-7-9-32-10-8-30/h1-6,11-13,22,31H,7-10H2	SOXWGEFOMMQSBW-UHFFFAOYSA-N	315601	(R)-(3-Chloro-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanolsee racemate::US10172859, Example 27::US10172859, Example 28::US10172859, Example 54::US11065253, Example 54::US9732094, Example 54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315601&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292264	383542355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659426	OC(c1ccc(nn1)C(O)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H19ClFN5O4/c25-17-11-18(26)16(10-15(17)23(32)19-3-4-20(24(33)34)30-29-19)22-14-2-1-13(9-21(14)27-12-28-22)31-5-7-35-8-6-31/h1-4,9-12,23,32H,5-8H2,(H,33,34)	FJAFQWYEJWQJQW-UHFFFAOYSA-N	315630	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid1H NMR (500 MHz, DMSO-d6) ppm = 13.30 (s, 1H), 9.11 (s, 1H), 8.21 (d, J = 8.7, 1H), 7.99 (d, J = 8.7, 1H), 7.87 (d, J = 7.6, 1H), 7.71 (d, J = 9.5, 1H), 7.55 (qd, J = 9.4, 2.7, 2H), 7.20 (d, J = 2.3, 1H), 7.08-6.66 (m, 1H), 6.42 (s, 1H), 3.80-3.75 (m, 4H), 3.49-3.44 (m, 4H)::US10172859, Example 55::US11065253, Example 55::US9732094, Example 55	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315630&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954856	383542375							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659428	OC(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23-28-5-6-33(23)31-21)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SWCDCNCTKFKWOI-UHFFFAOYSA-N	315631	US10172859, Example 56::US10172859, Example 57::US10172859, Example 63::US11065253, Example 63::US9732094, Example 63::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- imidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954834	383542376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659430	OC(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23-28-5-6-33(23)31-21)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SWCDCNCTKFKWOI-UHFFFAOYSA-N	315631	US10172859, Example 56::US10172859, Example 57::US10172859, Example 63::US11065253, Example 63::US9732094, Example 63::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- imidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954834	383542376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659432	COC(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN5O4/c1-35-25(34)21-5-4-20(30-31-21)24(33)16-11-17(19(27)12-18(16)26)23-15-3-2-14(10-22(15)28-13-29-23)32-6-8-36-9-7-32/h2-5,10-13,24,33H,6-9H2,1H3	VYOFGBFGFQHJOU-UHFFFAOYSA-N	315633	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid methyl ester1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.23 (d, J = 8.7, 1H), 8.01 (d, J = 8.7, 1H), 7.86 (d, J = 7.6, 1H), 7.70 (d, J = 9.5, 1H), 7.55 (qd, J = 9.4, 2.8, 2H), 7.20 (d, J = 2.4, 1H), 6.94-6.81 (m, 1H), 6.42 (s, 1H), 3.94 (s, 3H), 3.81-3.75 (m, 4H), 3.48-3.42 (m, 4H)::US10172859, Example 58::US11065253, Example 58::US9732094, Example 58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315633&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954925	383542377							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659434	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	TYZMCDRHMQABIJ-UHFFFAOYSA-N	315618	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- methyl-2H-pyridazin-3- one (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H), 7.93 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.61- 7.52 (m, 2H), 7.48 (d, J = 9.6, 1H), 7.21 (d, J = 2.4, 1H), 6.93 (d, J = 9.6, 1H), 6.60 (d, J = 4.8, 1H), 5.89 (d, J = 4.8, 1H), 3.80-3.75 (m, 4H), 3.59 (s, 3H), 3.48-3.43 (m, 4H)::US10172859, Example 44::US10172859, Example 45::US10172859, Example 59::US11065253, Example 59::US9732094, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954795	383542368							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659436	COc1cnc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-13-26-21(12-27-22)24(31)15-2-5-19(25)18(10-15)23-17-4-3-16(11-20(17)28-14-29-23)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WYEVURVICOACEU-UHFFFAOYSA-N	315626	US10172859, Example 52::US10172859, Example 53::US10172859, Example 60::US11065253, Example 60::US9732094, Example 60::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxy-pyrazin-2- yl)methanol (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.39-8.38 (m, 1H), 8.23 (d, J = 1.3, 1H), 7.66- 7.61 (m, 2H), 7.55-7.50 (m, 2H), 7.40-7.35 (m, 1H), 7.21-7.18 (m, 1H), 6.30 (d, J = 4.4, 1H), 5.88 (d, J = 4.4, 1H), 3.89 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954847	383542373							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659438	COc1cnc(cn1)C(O)c1ccc(OC)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25N5O4/c1-32-22-6-3-16(25(31)21-13-27-23(33-2)14-26-21)11-19(22)24-18-5-4-17(12-20(18)28-15-29-24)30-7-9-34-10-8-30/h3-6,11-15,25,31H,7-10H2,1-2H3	LLNFCLAEHDOZRS-UHFFFAOYSA-N	315636	US10172859, Example 61::US11065253, Example 61::US9732094, Example 61::[4-methoxy-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrazin-2- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.04 (s, 1H), 8.36-8.35 (m, 1H), 8.20 (d, J = 1.4, 1H), 7.53 (dd, J = 8.6, 2.3, 1H), 7.44 (dd, J = 9.4, 2.5, 1H), 7.38 (d, J = 9.4, 1H), 7.35 (d, J = 2.2, 1H), 7.17 (d, J = 8.6, 1H), 7.14 (d, J = 2.5, 1H), 6.13 (d, J = 4.4, 1H), 5.79 (d, J = 4.4, 1H), 3.88 (s, 3H), 3.79-3.75 (m, 4H), 3.66 (s, 3H), 3.43-3.38 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315636&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954789	383542378							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659440	NC(=O)c1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20ClFN6O3/c25-17-11-18(26)16(10-15(17)23(33)19-3-4-20(24(27)34)31-30-19)22-14-2-1-13(9-21(14)28-12-29-22)32-5-7-35-8-6-32/h1-4,9-12,23,33H,5-8H2,(H2,27,34)	VTXAYUFQWFXKTM-UHFFFAOYSA-N	315637	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}- pyridazine-3-carboxylic acid amide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.49 (s, 1H), 8.20 (d, J = 8.7, 1H), 8.00 (d, J = 8.7, 1H), 7.91-7.85 (m, 2H), 7.69 (d, J = 9.5, 1H), 7.59- 7.51 (m, 2H), 7.21 (d, J = 2.2, 1H), 6.84 (d, J = 5.0, 1H), 6.42 (d, J = 5.0, 1H), 3.80-3.75 (m, 4H), 3.48- 3.42 (m, 4H)::US10172859, Example 62::US11065253, Example 62::US9732094, Example 62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315637&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954890	383542379							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659442	OC(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23-28-5-6-33(23)31-21)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-35-10-8-32/h1-6,11-14,25,34H,7-10H2	SWCDCNCTKFKWOI-UHFFFAOYSA-N	315631	US10172859, Example 56::US10172859, Example 57::US10172859, Example 63::US11065253, Example 63::US9732094, Example 63::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- imidazo[1,2-b]pyridazin- 6-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954834	383542376							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659444	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C23H18Cl2FN5O2/c24-17-11-18(26)16(10-15(17)22(32)21-23(25)28-4-3-27-21)20-14-2-1-13(9-19(14)29-12-30-20)31-5-7-33-8-6-31/h1-4,9-12,22,32H,5-8H2	GLHIUOUYQQLZHP-UHFFFAOYSA-N	315639	US10172859, Example 64::US11065253, Example 64::US9732094, Example 64::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-chloropyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s, 1H), 8.61 (d, J = 2.4, 1H), 8.49 (d, J = 2.4, 1H), 8.00 (d, J = 7.7, 1H), 7.66 (d, J = 9.5, 1H), 7.64-7.55 (m, 2H), 7.22 (d, J = 2.4, 1H), 6.70 (d, J = 6.0, 1H), 6.42 (d, J = 6.0, 1H), 3.81-3.76 (m, 4H), 3.49-3.44 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315639&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292265	383542380							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659446	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccnn1	InChI=1S/C23H20FN5O2/c24-19-6-3-15(23(30)20-2-1-7-27-28-20)12-18(19)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	HOROSAWYDAWQIJ-UHFFFAOYSA-N	315640	US10172859, Example 65::US11065253, Example 65::US9732094, Example 65::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- pyridazin-3-yl methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (dd, J = 4.9, 1.7, 1H), 9.09 (s, 1H), 7.83 (dd, J = 8.6, 1.7, 1H), 7.72-7.65 (m, 3H), 7.52-7.49 (m, 2H), 7.42- 7.37 (m, 1H), 7.21-7.18 (m, 1H), 6.56 (d, J = 4.3, 1H), 6.12-6.09 (m, 1H), 3.80-3.75 (m, 4H), 3.46- 3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315640&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954922	383542381							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659448	COc1cnc(nc1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-17-12-26-24(27-13-17)23(31)15-2-5-20(25)19(10-15)22-18-4-3-16(11-21(18)28-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,23,31H,6-9H2,1H3	FPGGVKYDWGTPRN-UHFFFAOYSA-N	315641	US10172859, Example 66::US10172859, Example 67::US10172859, Example 69::US11065253, Example 69::US9732094, Example 69::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrirnidin-2- yl)methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.53 (s, 2H), 7.70-7.63 (m, 2H), 7.52 (s, 2H), 7.40-7.32 (m, 1H), 7.22-7.15 (m, 1H), 6.06 (d, J = 5.5, 1H), 5.86 (d, J = 5.5, 1H), 3.89 (s, 3H), 3.79- 3.76 (m, 4H), 3.45-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954782	383542382							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659450	COc1cnc(nc1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-17-12-26-24(27-13-17)23(31)15-2-5-20(25)19(10-15)22-18-4-3-16(11-21(18)28-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,23,31H,6-9H2,1H3	FPGGVKYDWGTPRN-UHFFFAOYSA-N	315641	US10172859, Example 66::US10172859, Example 67::US10172859, Example 69::US11065253, Example 69::US9732094, Example 69::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrirnidin-2- yl)methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.53 (s, 2H), 7.70-7.63 (m, 2H), 7.52 (s, 2H), 7.40-7.32 (m, 1H), 7.22-7.15 (m, 1H), 6.06 (d, J = 5.5, 1H), 5.86 (d, J = 5.5, 1H), 3.89 (s, 3H), 3.79- 3.76 (m, 4H), 3.45-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954782	383542382							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659452	CN(C)c1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25FN6O2/c1-31(2)23-8-7-21(29-30-23)25(33)16-3-6-20(26)19(13-16)24-18-5-4-17(14-22(18)27-15-28-24)32-9-11-34-12-10-32/h3-8,13-15,25,33H,9-12H2,1-2H3	LGTMOEJLQNXZRF-UHFFFAOYSA-N	315643	(6-Dimethylamino- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.65-7.56 (m, 2H), 7.55-7.48 (m, 2H), 7.43- 7.34 (m, 2H), 7.24-7.17 (m, 1H), 7.07 (d, J = 9.4, 1H), 6.27 (d, J = 4.4, 1H), 5.93 (d, J = 4.4, 1H), 3.81- 3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.06 (s, 6H)::US10172859, Example 68::US11065253, Example 68::US9732094, Example 68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315643&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954889	383542383							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659454	COc1cnc(nc1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-17-12-26-24(27-13-17)23(31)15-2-5-20(25)19(10-15)22-18-4-3-16(11-21(18)28-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,23,31H,6-9H2,1H3	FPGGVKYDWGTPRN-UHFFFAOYSA-N	315641	US10172859, Example 66::US10172859, Example 67::US10172859, Example 69::US11065253, Example 69::US9732094, Example 69::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methoxypyrirnidin-2- yl)methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.53 (s, 2H), 7.70-7.63 (m, 2H), 7.52 (s, 2H), 7.40-7.32 (m, 1H), 7.22-7.15 (m, 1H), 6.06 (d, J = 5.5, 1H), 5.86 (d, J = 5.5, 1H), 3.89 (s, 3H), 3.79- 3.76 (m, 4H), 3.45-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954782	383542382							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659456	Cc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-2-7-21(29-28-15)24(31)16-3-6-20(25)19(12-16)23-18-5-4-17(13-22(18)26-14-27-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	SCZCGSZBCLOCQY-UHFFFAOYSA-N	315645	US10172859, Example 70::US11065253, Example 70::US9732094, Example 70::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.72-7.61 (m, 3H), 7.58-7.47 (m, 3H), 7.43- 7.33 (m, 1H), 7.22-7.16 (m, 1H), 6.50 (d, J = 4.0, 1H), 6.07 (d, J = 3.8, 1H), 3.77 (t, J = 5.9, 3.9, 4H), 3.44 (t, J = 4.9, 4H), 2.58 (s, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315645&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954787	383542384							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659458	COc1ccc(nn1)[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3/t24-/m1/s1	IDTQOMSFKJPUNB-XMMPIXPASA-N	315646	(R)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.70 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H), 7.53- 7.50 (m, 2H), 7.42-7.37 (m, 1H), 7.22-7.19 (m, 2H), 6.48 (d, J = 4.4, 1H), 6.02 (d, J = 4.4, 1 H), 4.00 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H)::US10172859, Example 71::US11065253, Example 71::US9732094, Example 71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315646&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711812	383542385							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659460	COc1ccc(nn1)[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3/t24-/m0/s1	IDTQOMSFKJPUNB-DEOSSOPVSA-N	315647	(S)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.69 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H), 7.53- 7.50 (m, 2H), 7.41-7.37 (m, 1H), 7.21-7.19 (m, 2H), 6.48 (d, J = 4.4, 1H), 6.02 (d, J = 4.4, 1H), 4.00 (s, 3H), 3.79-3.76 (m, 4H), 3.46-3.42 (m, 4H)::US10172859, Example 72::US11065253, Example 72::US9732094, Example 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315647&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954951	383542386							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659462	COC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(OC)nn1	InChI=1S/C25H24FN5O3/c1-32-23-8-7-21(29-30-23)25(33-2)16-3-6-20(26)19(13-16)24-18-5-4-17(14-22(18)27-15-28-24)31-9-11-34-12-10-31/h3-8,13-15,25H,9-12H2,1-2H3	UDKXIJIDLGKASD-UHFFFAOYSA-N	315648	4-{2-Fluoro-5-[methoxy- (6-methoxy-pyridazin-3- yl)methyl]phenyl}-7- morpholin-4-yl- quinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.69 (d, J = 9.1, 1H), 7.65-7.61 (m, 2H), 7.54- 7.48 (m, 2H), 7.45-7.40 (m, 1H), 7.23 (d, J = 9.2, 1H), 7.21-7.19 (m, 1H), 5.71 (s, 1H), 4.01 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.36 (s, 3H)::US10172859, Example 73::US11065253, Example 73::US9732094, Example 73	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315648&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954802	383542387							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659464	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	IDTQOMSFKJPUNB-UHFFFAOYSA-N	315649	US10172859, Example 74::US11065253, Example 256::US9732094, Example 74::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (6-methoxypyridazin-3- yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 7.69 (d, J = 9.2, 1H), 7.67-7.61 (m, 2H), 7.54- 7.48 (m, 2H), 7.42-7.36 (m, 1H), 7.22-7.17 (m, 2H), 6.51-6.45 (m, 1H), 6.04-6.00 (m, 1H), 4.00 (s, 3H), 3.80-3.74 (m, 4H), 3.47-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315649&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292267	383542388							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659466	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1C2CCC1COC2)c1ccc(=O)[nH]n1			315650	6-({4-Fluoro-3-[7-(3- oxa-8-aza-bicyclo- [3.2.1]oct-8-yl)- quinazolin-4-yl]phenyl}- hydroxymethyl)-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 12.88- 12.84 (m, 1H), 9.04 (s, 1H), 7.63-7.57 (m, 2H), 7.50-7.45 (m, 2H), 7.44-7.38 (m, 2H), 7.14 (d, J = 2.4, 1H), 6.87 (dd, J = 9.8, 2.2, 1H), 6.42 (d, J = 4.4, 1H), 5.68-5.64 (m, 1H), 4.55-4.46 (m, 2H), 3.69 (d, J = 10.9, 2H), 3.54 (d, J = 10.4, 2H), 2.09-1.94 (m, 4H)::US10172859, Example 75::US11065253, Example 75::US9732094, Example 75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315650&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106836	383542389							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659468	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(=O)[nH]n1			315651	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2H- pyridazin-3-one (Ena 2)1H NMR (400 MHz, DMSO-d6) ppm = 12.86 (s, 1H), 9.10 (s, 1H), 7.64-7.58 (m, 2H), 7.55-7.50 (m, 2H), 7.48 (d, J = 9.8, 1H), 7.45-7.38 (m, 1H), 7.23-7.16 (m, 1H), 6.87 (d, J = 9.8, 1H), 6.44 (d, J = 4.3, 1H), 5.70-5.62 (m, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 367::US10172859, Example 76::US11065253, Example 76::US9732094, Example 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315651&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106837	383542390							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659470	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(F)cncc1Cl	InChI=1S/C24H19ClF2N4O2/c25-18-11-28-12-20(27)22(18)24(32)14-1-4-19(26)17(9-14)23-16-3-2-15(10-21(16)29-13-30-23)31-5-7-33-8-6-31/h1-4,9-13,24,32H,5-8H2	UOGVCLMTQITAPC-UHFFFAOYSA-N	315652	(3-Chloro-5-fluoro- pyridin-4-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.58-8.53 (m, 2H), 7.65-7.56 (m, 2H), 7.56- 7.47 (m, 2H), 7.46-7.38 (m, 1H), 7.23-7.17 (m, 1H), 6.65 (d, J = 4.7, 1H), 6.33 (d, J = 4.7, 1H), 3.80- 3.75 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 77::US11065253, Example 77::US9732094, Example 77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315652&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292266	383542391							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659472	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 226::US10172859, Example 238::US10172859, Example 243::US10172859, Example 259::US10172859, Example 78::US11065253, Example 259::US9732094, Example 259::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659474	CCOc1cnnc(c1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O3/c1-2-34-18-13-23(30-29-14-18)25(32)16-3-6-21(26)20(11-16)24-19-5-4-17(12-22(19)27-15-28-24)31-7-9-33-10-8-31/h3-6,11-15,25,32H,2,7-10H2,1H3	IQAJYGPAYOWOTI-UHFFFAOYSA-N	315654	(5-Ethoxypyridazin-3- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.84 (d, J = 2.9, 1H), 7.72-7.66 (m, 2H), 7.52-7.49 (m, 2H), 7.41-7.36 (m, 1H), 7.30 (d, J = 2.9, 1H), 7.21-7.18 (m, 1H), 6.52 (d, J = 4.5, 1H), 6.04 (d, J = 4.5, 1H), 4.26-4.16 (m, 2H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 1.34 (t, J = 6.9, 3H).::US10172859, Example 79::US11065253, Example 79::US9732094, Example 79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315654&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954937	383542393							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659476	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1C(F)(F)F	InChI=1S/C25H20F4N4O2/c26-20-6-3-15(24(34)23-19(25(27,28)29)2-1-7-30-23)12-18(20)22-17-5-4-16(13-21(17)31-14-32-22)33-8-10-35-11-9-33/h1-7,12-14,24,34H,8-11H2	SJVDCFJVJFVWBU-UHFFFAOYSA-N	315655	US10172859, Example 80::US11065253, Example 80::US9732094, Example 80::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-trifluoro- methylpyridin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.90-8.85 (m, 1H), 8.20 (dd, J = 8.1, 1.6, 1H), 7.63 (dd, J = 6.9, 2.3, 1H), 7.60-7.51 (m, 4H), 7.38 (dd, J = 9.9, 8.6, 1H), 7.21-7.18 (m, 1H), 6.32 (d, J = 6.3, 1H), 6.12 (d, J = 6.0, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315655&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955010	383542394							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659478	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1OC(F)F	InChI=1S/C25H21F3N4O3/c26-19-6-3-15(24(33)23-21(35-25(27)28)2-1-7-29-23)12-18(19)22-17-5-4-16(13-20(17)30-14-31-22)32-8-10-34-11-9-32/h1-7,12-14,24-25,33H,8-11H2	LBUXFIGKVFCKLV-UHFFFAOYSA-N	315656	(3-Difluoromethoxy- pyridin-2-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.46 (dd, J = 4.6, 1.3, 1H), 7.67-7.64 (m, 1H), 7.62- 7.57 (m, 2H), 7.54-7.49 (m, 2H), 7.42 (dd, J = 8.3, 4.6, 1H), 7.40-7.10 (m, 3H), 6.14-6.07 (m, 2H), 3.81-3.75 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 81::US11065253, Example 81::US9732094, Example 81	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315656&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292452	383542395							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659480	Cc1nccnc1[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3/t24-/m0/s1	PCPCDRDQIBENHU-DEOSSOPVSA-N	315657	(S)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 8.44 (s, 2H), 7.64-7.51 (m, 4H), 7.44-7.35 (m, 1H), 7.20 (s, 1H), 6.31 (d, J = 5.5, 1H), 6.09 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.56 (s, 3H).::US10172859, Example 82::US11065253, Example 82::US9732094, Example 82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315657&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966367	383542396							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659482	Cc1nccnc1[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3/t24-/m1/s1	PCPCDRDQIBENHU-XMMPIXPASA-N	315658	(R)-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.49 (m, 4H), 7.43-7.34 (m, 1H), 7.19 (s, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.82-3.73 (m, 4H), 3.48-3.40 (m, 4H), 2.55 (s, 3H).::US10172859, Example 83::US11065253, Example 83::US9732094, Example 83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315658&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292453	383542397							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659484	Cc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)18-11-17(19(25)12-20(18)26)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	KEMOASSFPWYYBE-UHFFFAOYSA-N	315660	US10172859, Example 85::US10172859, Example 86::US11065253, Example 86::US9732094, Example 86::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl) methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315660&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292454	383542399							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659486	Cc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)18-11-17(19(25)12-20(18)26)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	KEMOASSFPWYYBE-UHFFFAOYSA-N	315660	US10172859, Example 85::US10172859, Example 86::US11065253, Example 86::US9732094, Example 86::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl) methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315660&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292454	383542399							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659488	Cc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)18-11-17(19(25)12-20(18)26)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	KEMOASSFPWYYBE-UHFFFAOYSA-N	315660	US10172859, Example 85::US10172859, Example 86::US11065253, Example 86::US9732094, Example 86::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl) methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315660&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292454	383542399							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659490	COc1cncnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-21-12-26-13-28-23(21)24(31)15-2-5-19(25)18(10-15)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	PYONFGNQOKWYAY-UHFFFAOYSA-N	315662	US10172859, Example 87::US11065253, Example 87::US9732094, Example 87::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 8.82 (s, 1H), 8.58 (s, 1H), 7.67-7.61 (m, 2H), 7.55-7.52 (m, 2H), 7.41-7.34 (m, 1H), 7.23- 7.19 (m, 1H), 6.13 (d, J = 6.1, 1H), 6.07 (d, J = 6.2, 1H), 3.95 (s, 3H), 3.83-3.76 (m, 4H), 3.49-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315662&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292457	383542400							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659492	Cc1cnc(C)c(n1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23F2N5O2/c1-14-12-28-15(2)23(31-14)25(33)19-10-18(20(26)11-21(19)27)24-17-4-3-16(9-22(17)29-13-30-24)32-5-7-34-8-6-32/h3-4,9-13,25,33H,5-8H2,1-2H3	CNLAIWPYPBGUKK-UHFFFAOYSA-N	315663	US10172859, Example 88::US11065253, Example 88::US9732094, Example 88::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3,6-dimethyl- pyrazin-2-yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.13 (s, 1H), 8.35 (s, 1H), 7.88 (t, J = 8.2, 1H), 7.61 (dd, J = 9.4, 3.0, 1H), 7.56 (dd, J = 9.5, 2.5, 1H), 7.42 (t, J = 10.2, 1H), 7.23 (d, J = 2.4, 1H), 6.31 (d, J = 5.9, 1H), 6.22 (d, J = 5.6, 1H), 3.85-3.75 (m, 4H), 3.51-3.43 (m, 4H), 2.58 (s, 3H), 2.40 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315663&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292456	383542401							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659494	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H20ClN5O2S/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-10-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	SZNBSUDBRGPGNX-UHFFFAOYSA-N	315664	US10172859, Example 89::US11065253, Example 89::US9732094, Example 89::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s, 1H), 9.04 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.89 (d, J = 2.1, 1H), 7.76 (d, J = 9.4, 1H), 7.73 (dd, J = 8.2, 2.2, 1H), 7.69 (d, J = 8.2, 1H), 7.62 (d, J = 5.6, 1H), 7.47 (dd, J = 9.5, 2.6, 1H), 7.20-7.16 (m, 2H), 6.47 (d, J = 4.9, 1H), 3.81-3.74 (m, 4H), 3.47-3.39 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315664&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292652	383542402							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659496	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H19F2N5O2S/c26-19-11-20(27)18(24(33)23-16-3-8-35-25(16)31-13-30-23)10-17(19)22-15-2-1-14(9-21(15)28-12-29-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	CTTOCNUUBHCIRF-UHFFFAOYSA-N	315665	US10172859, Example 90::US11065253, Example 90::US9732094, Example 90::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s, 1H), 9.05 (s,1H), 8.47 (d, J = 5.6, 1H), 7.76 (t, J = 8.0, 1H), 7.61 (d, J = 5.6, 1H), 7.55-7.46 (m, 3H), 7.20- 7.17 (m, 2H), 6.32 (d, J = 4.7, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315665&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696337	383542403							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659498	Cn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)16-5-8-20(26)19(13-16)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	IVAQITIIINVXDO-UHFFFAOYSA-N	315666	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.60-7.56 (m, 2H), 7.55-7.51 (m, 2H), 7.48- 7.43 (m, 1H), 7.40 (dd, J = 9.1, 6.9, 1H), 7.21-7.19 (m, 1H), 6.52 (d, J = 5.3, 1H), 6.36 (dd, J = 9.1, 1.4, 1H), 6.25 (dd, J = 7.0, 1.4, 1H), 5.94 (d, J = 5.1, 1H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.38 (s, 3H).::US10172859, Example 375::US10172859, Example 376::US10172859, Example 91::US11065253, Example 91::US9732094, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315666&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292653	383542404							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659500	OC(c1ccc(=O)[nH]n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1			315667	3-[[2-Chloro-4-fluoro-5- (7-morpholino- quinazolin-4-yl)phenyl]- hydroxymethyl]-1H- pyridazin-6-one1H NMR (400 MHz, DMSO-d6) ppm = 12.89 (d,J = 2.4, 1H), 9.12 (s, 1H), 7.92 (d, J = 7.7, 1H), 7.68(d, J = 9.5, 1H), 7.59-7.55 (m, 2H), 7.53 (d, J = 9.8,1H), 7.21 (d, J = 2.2, 1H), 6.90 (dd, J = 9.8, 2.3, 1H),6.61 (d, J = 5.1, 1H), 5.89 (d, J = 5.1, 1H), 3.81-3.76(m, 4H), 3.48-3.44 (m, 4H)::US10172859, Example 92::US11065253, Example 92::US9732094, Example 92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315667&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106838	383542405							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659502	CCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-2-32-23(33)6-5-21(30-32)25(34)17-12-18(20(27)13-19(17)26)24-16-4-3-15(11-22(16)28-14-29-24)31-7-9-35-10-8-31/h3-6,11-14,25,34H,2,7-10H2,1H3	ROTFCYSSIJCDLR-UHFFFAOYSA-N	315668	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-ethyl- 2H-pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.59-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.08-3.95 (m, 2H), 3.81-3.74 (m, 4H),3.49-3.41 (m, 4H), 1.20 (t, J = 7.2, 3H)::US10172859, Example 93::US10172859, Example 96::US10172859, Example 97::US11065253, Example 97::US9732094, Example 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292656	383542406							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659504	NCCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24ClFN6O3/c26-19-13-20(27)18(12-17(19)25(35)21-3-4-23(34)33(31-21)6-5-28)24-16-2-1-15(11-22(16)29-14-30-24)32-7-9-36-10-8-32/h1-4,11-14,25,35H,5-10,28H2	JVKNZLYEUFZUIQ-UHFFFAOYSA-N	315669	2-(2-Amino-ethyl)-6-{[2- Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.60-7.52(m, 2H), 7.48 (d, J = 9.7, 1H), 7.21 (d, J = 2.2, 1H),6.94 (d, J = 9.6, 1H), 6.72-6.57 (m, 1H), 5.91 (s,1H), 4.10-3.96 (m, 2H), 3.82-3.73 (m, 4H), 3.48-3.43 (m, 4H), 2.88 (t, J = 6.6, 2H)::US10172859, Example 94::US11065253, Example 94::US9732094, Example 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315669&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954771	383542407							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659506	OC(c1ccc(=O)n(n1)C1CC1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O3/c27-20-13-21(28)19(12-18(20)26(35)22-5-6-24(34)33(31-22)15-1-2-15)25-17-4-3-16(11-23(17)29-14-30-25)32-7-9-36-10-8-32/h3-6,11-15,26,35H,1-2,7-10H2	SFQDWLSJUWKEID-UHFFFAOYSA-N	315670	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2- cyclopropyl-2H- pyridazin-3-one1H NMR (400 MHz, Methylenchlorid-d2) ppm = 9.04(s, 1H), 7.71 (d, J = 7.6, 1H), 7.49 (dd, J = 9.3, 3.5,1H), 7.26-7.20 (m, 2H), 7.18-7.14 (m, 2H), 6.74(d, J = 9.6, 1H), 5.97 (s, 1H), 4.03-3.94 (m, 1H),3.82-3.74 (m, 4H), 3.39-3.31 (m, 4H), 0.98-0.82(m, 4H)::US10172859, Example 95::US11065253, Example 95::US9732094, Example 95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315670&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954967	383542408							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659508	CCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-2-32-23(33)6-5-21(30-32)25(34)17-12-18(20(27)13-19(17)26)24-16-4-3-15(11-22(16)28-14-29-24)31-7-9-35-10-8-31/h3-6,11-14,25,34H,2,7-10H2,1H3	ROTFCYSSIJCDLR-UHFFFAOYSA-N	315668	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-ethyl- 2H-pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.59-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.08-3.95 (m, 2H), 3.81-3.74 (m, 4H),3.49-3.41 (m, 4H), 1.20 (t, J = 7.2, 3H)::US10172859, Example 93::US10172859, Example 96::US10172859, Example 97::US11065253, Example 97::US9732094, Example 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292656	383542406							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659510	CCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-2-32-23(33)6-5-21(30-32)25(34)17-12-18(20(27)13-19(17)26)24-16-4-3-15(11-22(16)28-14-29-24)31-7-9-35-10-8-31/h3-6,11-14,25,34H,2,7-10H2,1H3	ROTFCYSSIJCDLR-UHFFFAOYSA-N	315668	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-ethyl- 2H-pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.59-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.08-3.95 (m, 2H), 3.81-3.74 (m, 4H),3.49-3.41 (m, 4H), 1.20 (t, J = 7.2, 3H)::US10172859, Example 93::US10172859, Example 96::US10172859, Example 97::US11065253, Example 97::US9732094, Example 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292656	383542406							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659512	NC(=O)Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O4/c26-18-11-19(27)17(10-16(18)25(36)20-3-4-23(35)33(31-20)12-22(28)34)24-15-2-1-14(9-21(15)29-13-30-24)32-5-7-37-8-6-32/h1-4,9-11,13,25,36H,5-8,12H2,(H2,28,34)	BXOINBJDZSONOX-UHFFFAOYSA-N	315673	2-(3-{[2-Chloro-4- fluoro-5-(7-morpholin- 4-ylquinazolin-4-yl)- phenyl]hydroxymethyl}- 6-oxo-6H-pyridazin-1- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s, 1H),7.93 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H), 7.58 (dd,J = 9.4, 3.0, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.51-7.44 (m, 2H), 7.21 (d, J = 2.4, 1H), 7.15 (s, 1H),6.94 (d, J = 9.6, 1H), 6.62 (d, J = 4.8, 1H), 5.89 (d,J = 4.8, 1H), 4.61-4.51 (m, 2H), 3.81-3.75 (m, 4H),3.48-3.42 (m, 4H)::US10172859, Example 98::US11065253, Example 98::US9732094, Example 98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315673&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954848	383542409							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659514	OCCn1nc(ccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O4/c26-19-13-20(27)18(12-17(19)25(35)21-3-4-23(34)32(30-21)5-8-33)24-16-2-1-15(11-22(16)28-14-29-24)31-6-9-36-10-7-31/h1-4,11-14,25,33,35H,5-10H2	HPUBJROQDSYMAY-UHFFFAOYSA-N	315674	6-{[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2-(2- hydroxy-ethyl)-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s, 1H),7.94 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H), 7.60-7.52(m, 2H), 7.46 (d, J = 9.6, 1H), 7.22 (d, J = 2.3, 1H),6.92 (d, J = 9.6, 1H), 6.61 (d, J = 4.8, 1H), 5.90 (d,J = 4.8, 1H), 4.75 (t, J = 5.8, 1H), 4.11-4.00 (m, 2H),3.82-3.74 (m, 4H), 3.65 (q, J = 6.2, 2H), 3.49-3.42::US10172859, Example 99::US11065253, Example 99::US9732094, Example 99	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315674&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954862	383542410							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659516	OC(c1ccc(OC2COC2)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O4/c27-20-11-21(28)19(10-18(20)26(34)22-3-4-24(32-31-22)37-16-12-36-13-16)25-17-2-1-15(9-23(17)29-14-30-25)33-5-7-35-8-6-33/h1-4,9-11,14,16,26,34H,5-8,12-13H2	SRYMLVUNMNZEHF-UHFFFAOYSA-N	315675	US10172859, Example 100::US11065253, Example 100::US9732094, Example 100::[2-Chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-[6-(oxetan-3-yloxy)pyridazin-3-yl]methanol 	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315675&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292655	383542411							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659518	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::US11065253, Example 104::US9732094, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659520	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::US11065253, Example 104::US9732094, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659522	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::US11065253, Example 104::US9732094, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659524	CC(Oc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)C#N	InChI=1S/C26H22ClFN6O3/c1-15(13-29)37-24-5-4-22(32-33-24)26(35)18-11-19(21(28)12-20(18)27)25-17-3-2-16(10-23(17)30-14-31-25)34-6-8-36-9-7-34/h2-5,10-12,14-15,26,35H,6-9H2,1H3	JEOIEFCSPPXNAG-UHFFFAOYSA-N	315676	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (d,J = 2.7, 1H), 7.93 (dd, J = 11.2, 7.7, 1H), 7.84 (dd,J = 16.3, 9.2, 1H), 7.70-7.65 (m, 1H), 7.63-7.57 (m, 1H), 7.57-7.51 (m, 1H), 7.38 (dd,J = 9.1, 3.5, 1H), 7.21 (d, J = 2.4, 1H), 6.71 (dd,J = 10.3, 5.0, 1H), 6.28 (dd, J = 9.5, 5.0, 1H), 5.95-5.87 (m, 1H), 3.81-3.74 (m, 4H), 3.48-3.42(m, 4H), 1.76-1.70 (m, 3H)::US10172859, Example 101::US10172859, Example 102::US10172859, Example 103::US10172859, Example 104::US11065253, Example 104::US9732094, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86293039	383542412							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659526	OCCOc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O4/c26-20-4-1-16(24(33)23-25(35-12-9-32)28-6-5-27-23)13-19(20)22-18-3-2-17(14-21(18)29-15-30-22)31-7-10-34-11-8-31/h1-6,13-15,24,32-33H,7-12H2	KVAPMCUPBPNTHD-UHFFFAOYSA-N	315680	2-(3-{[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl- oxy)ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.19 (d, J = 2.8, 1H), 8.12 (d, J = 2.8, 1H),7.70-7.64 (m, 2H), 7.54-7.51 (m, 2H), 7.38-7.33 (m, 1H), 7.21-7.19 (m, 1H), 6.14 (d,J = 5.9, 1H), 6.00 (d, J = 6.0, 1H), 4.86 (t, J = 5.7,1H), 4.34-4.30 (m, 2H), 3.80-3.75 (m, 4H),3.74-3.69 (m, 2H), 3.46-3.42 (m, 4H)::US10172859, Example 105::US11065253, Example 105::US9732094, Example 105	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315680&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954969	383542413							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659528	OCCNc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25FN6O3/c26-20-4-1-16(24(34)23-25(29-7-10-33)28-6-5-27-23)13-19(20)22-18-3-2-17(14-21(18)30-15-31-22)32-8-11-35-12-9-32/h1-6,13-15,24,33-34H,7-12H2,(H,28,29)	YVVAIAKPXYKXCT-UHFFFAOYSA-N	315681	2-(3-{[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl- amino)ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.91 (d, J = 2.7, 1H), 7.67 (d, J = 2.8, 1H),7.63-7.58 (m, 2H), 7.55-7.49 (m, 2H), 7.41-7.35 (m, 1H), 7.20 (d, J = 2.0, 1H), 6.82-6.75(m, 2H), 5.91 (d, J = 4.2, 1H), 4.74 (t, J = 5.1, 1H),3.82-3.73 (m, 4H), 3.60-3.45 (m, 8H)::US10172859, Example 106::US11065253, Example 106::US9732094, Example 106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315681&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954909	383542414							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659530	OC(c1ccc(OCCC#N)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H22ClFN6O3/c27-20-14-21(28)19(13-18(20)26(35)22-4-5-24(33-32-22)37-9-1-6-29)25-17-3-2-16(12-23(17)30-15-31-25)34-7-10-36-11-8-34/h2-5,12-15,26,35H,1,7-11H2	ZOBQEXZTIUCXDW-UHFFFAOYSA-N	315682	3-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)propionitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.95 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H),7.59 (dd, J = 9.4, 3.2, 1H), 7.55-7.49 (m, 2H),7.21 (d, J = 2.4, 1H), 6.99 (d, J = 9.6, 1H), 6.67(d, J = 4.9, 1H), 5.92 (d, J = 4.9, 1H), 4.31-4.17(m, 2H), 3.81-3.75 (m, 4H), 3.49-3.42 (m,4H), 2.99-2.88 (m, 2H)::US10172859, Example 107::US11065253, Example 107::US9732094, Example 107	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315682&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955015	383542415							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659532	CSc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O2S/c1-34-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	QGUGXNKWEKXBMQ-UHFFFAOYSA-N	315683	US10172859, Example 108::US11065253, Example 108::US9732094, Example 108::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methyl- sulfanylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.90 (d, J = 7.7, 1H), 7.68 (d, J = 9.5, 1H),7.66-7.60 (m, 2H), 7.60-7.56 (m, 1H), 7.54(dd, J = 9.4, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.68(s, 1H), 6.25 (s, 1H), 3.80-3.76 (m, 4H), 3.47-3.43 (m, 4H), 2.61 (s, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315683&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292847	383542416							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659534	COc1cc(C)c(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-14-9-22(34-2)30-31-23(14)25(33)17-11-18(20(27)12-19(17)26)24-16-4-3-15(10-21(16)28-13-29-24)32-5-7-35-8-6-32/h3-4,9-13,25,33H,5-8H2,1-2H3	USOUBBMUUGTPON-UHFFFAOYSA-N	315684	US10172859, Example 109::US11065253, Example 109::US9732094, Example 109::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- 4-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 7.99 (d, J = 7.8, 1H), 7.67-7.61 (m, 2H),7.57 (dd, J = 9.4, 2.6, 1H), 7.23 (d, J = 2.5, 1H),7.10 (d, J = 1.1, 1H), 6.42 (d, J = 6.4, 1H), 6.25(d, J = 6.3, 1H), 3.96 (s, 3H), 3.82-3.75 (m,4H), 3.50-3.42 (m, 4H), 2.49-2.46 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315684&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954913	383542417							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659536	COc1nnc(cc1C)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-14-9-22(30-31-25(14)34-2)24(33)17-11-18(20(27)12-19(17)26)23-16-4-3-15(10-21(16)28-13-29-23)32-5-7-35-8-6-32/h3-4,9-13,24,33H,5-8H2,1-2H3	ZTLYNAMLFWWNRW-UHFFFAOYSA-N	315685	US10172859, Example 110::US11065253, Example 110::US9732094, Example 110::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- 5-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.8, 1H), 7.66 (d, J = 9.6, 1H),7.59 (dd, J = 9.4, 3.3, 1H), 7.56-7.52 (m, 2H),7.21 (d, J = 2.4, 1H), 6.54 (d, J = 4.9, 1H), 6.18(d, J = 4.9, 1H), 4.02 (s, 3H), 3.80-3.75 (m,4H), 3.48-3.43 (m, 4H), 2.17 (d, J = 1.0, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315685&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954772	383542418							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659538	NC(=O)COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O4/c26-18-11-19(27)17(10-16(18)25(35)20-3-4-23(32-31-20)37-12-22(28)34)24-15-2-1-14(9-21(15)29-13-30-24)33-5-7-36-8-6-33/h1-4,9-11,13,25,35H,5-8,12H2,(H2,28,34)	SDAGDBFBEANYBV-UHFFFAOYSA-N	315686	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yloxy)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.92 (d, J = 7.7, 1H), 7.74 (d, J = 9.1, 1H),7.66 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H),7.57-7.49 (m, 2H), 7.27 (d, J = 9.1, 1H), 7.23-7.16 (m, 2H), 6.63 (d, J = 5.0, 1H), 6.23 (d,J = 5.0, 1H), 4.81 (s, 2H), 3.81-3.75 (m, 4H),3.49-3.43 (m, 4H)::US10172859, Example 111::US11065253, Example 111::US9732094, Example 111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315686&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954830	383542419							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659540	COCCOc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H25ClFN5O4/c1-35-10-11-37-24-5-4-22(31-32-24)26(34)18-13-19(21(28)14-20(18)27)25-17-3-2-16(12-23(17)29-15-30-25)33-6-8-36-9-7-33/h2-5,12-15,26,34H,6-11H2,1H3	VEXMWYKCSKRUDC-UHFFFAOYSA-N	315687	US10172859, Example 112::US11065253, Example 112::US9732094, Example 112::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-[6-(2- methoxyethoxy)- pyridazin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H),7.54 (dd, J = 9.5, 2.5, 1H), 7.25-7.19 (m, 2H),6.61 (d, J = 5.0, 1H), 6.23 (d, J = 5.0, 1H), 4.54-4.50 (m, 2H), 3.80-3.75 (m, 4H), 3.71-3.67(m, 2H), 3.48-3.43 (m, 4H), 3.29 (s, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315687&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955001	383542420							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659542	OC(c1ccc(OCC(O)=O)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN5O5/c26-18-11-19(27)17(10-16(18)25(35)20-3-4-22(31-30-20)37-12-23(33)34)24-15-2-1-14(9-21(15)28-13-29-24)32-5-7-36-8-6-32/h1-4,9-11,13,25,35H,5-8,12H2,(H,33,34)	JNGCYUIWAFFJPM-UHFFFAOYSA-N	315688	(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetic acid1H NMR (500 MHz, DMSO-d6) ppm = 12.91 (s,1H), 9.12 (s, 1H), 7.92 (d, J = 7.7, 1H), 7.75 (d,J = 9.1, 1H), 7.66 (d, J = 9.5, 1H), 7.59 (dd, J = 9.4,3.3, 1H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.31 (d,J = 9.1, 1H), 7.21 (d, J = 2.4, 1H), 6.66 (s, 1H),6.23 (s, 1H), 4.97 (s, 2H), 3.81-3.75 (m, 4H),3.48-3.43 (m, 4H)::US10172859, Example 113::US11065253, Example 113::US9732094, Example 113	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315688&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954993	383542421							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659544	COC(=O)COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O5/c1-36-24(34)13-38-23-5-4-21(31-32-23)26(35)17-11-18(20(28)12-19(17)27)25-16-3-2-15(10-22(16)29-14-30-25)33-6-8-37-9-7-33/h2-5,10-12,14,26,35H,6-9,13H2,1H3	GLBIKYWGGXTOCO-UHFFFAOYSA-N	315690	(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetic acid methyl ester1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.92 (d, J = 7.7, 1H), 7.77 (d, J = 9.1, 1H),7.67 (d, J = 9.5, 1H), 7.59 (dd, J = 9.3, 3.2, 1H),7.57-7.51 (m, 1H), 7.35 (d, J = 9.1, 1H), 7.23-7.19 (m, 1H), 6.62 (s, 1H), 6.23 (s, 1H), 5.07(s, 2H), 3.81-3.75 (m, 4H), 3.67 (s, 3H), 3.49-3.44 (m, 4H)::US10172859, Example 114::US11065253, Example 114::US9732094, Example 114	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315690&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954756	383542423							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659546	OC(c1ccc(OCC(F)(F)F)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClF4N5O3/c26-18-11-19(27)17(10-16(18)24(36)20-3-4-22(34-33-20)38-12-25(28,29)30)23-15-2-1-14(9-21(15)31-13-32-23)35-5-7-37-8-6-35/h1-4,9-11,13,24,36H,5-8,12H2	XBIFOHKQPCJZBA-UHFFFAOYSA-N	315691	US10172859, Example 115::US11065253, Example 115::US9732094, Example 115::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-[6-(2,2,2- trifluoroethoxy)- pyridazin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.91 (d, J = 7.7, 1H), 7.81 (d, J = 9.2, 1H),7.66 (d, J = 9.5, 1H), 7.60-7.52 (m, 2H), 7.41(d, J = 9.1, 1H), 7.20 (d, J = 2.3, 1H), 6.72 (d,J = 5.0, 1H), 6.26 (d, J = 4.5, 1H), 5.22-5.08 (m,2H), 3.80-3.75 (m, 4H), 3.47-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315691&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954817	383542424							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659548	OCCOc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O4/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23(31-30-21)36-10-7-33)24-16-2-1-15(11-22(16)28-14-29-24)32-5-8-35-9-6-32/h1-4,11-14,25,33-34H,5-10H2	HJYNFJSAPISPIC-UHFFFAOYSA-N	315692	2-(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.71-7.64 (m, 2H),7.61-7.51 (m, 2H), 7.23-7.17 (m, 2H), 6.60(d, J = 5.0, 1H), 6.22 (d, J = 5.0, 1H), 4.84 (t,J = 5.5, 1H), 4.44-4.39 (m, 2H), 3.81-3.76 (m,4H), 3.74 (q, J = 5.4, 2H), 3.48-3.43 (m, 4H)::US10172859, Example 116::US11065253, Example 116::US9732094, Example 116	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315692&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954855	383542425							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659550	Nc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN6O2/c24-17-11-18(25)16(10-15(17)22(32)21-23(26)28-4-3-27-21)20-14-2-1-13(9-19(14)29-12-30-20)31-5-7-33-8-6-31/h1-4,9-12,22,32H,5-8H2,(H2,26,28)	NLBRAVXIOQVDEK-UHFFFAOYSA-N	315693	(3-Amino-pyrazin-2- yl)-[2-chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.14 (s,1H), 7.91 (d, J = 7.8, 1H), 7.87 (d, J = 2.7, 1H),7.67-7.55 (m, 4H), 7.21 (d, J = 2.5, 1H), 6.41(s, 3H), 6.09 (s, 1H), 3.81-3.75 (m, 4H), 3.50-3.45 (m, 4H)::US10172859, Example 117::US11065253, Example 117::US9732094, Example 117	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315693&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954853	383542426							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659552	OC(c1ccc(nn1)C#N)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H18ClFN6O2/c25-19-11-20(26)18(10-17(19)24(33)21-4-1-14(12-27)30-31-21)23-16-3-2-15(9-22(16)28-13-29-23)32-5-7-34-8-6-32/h1-4,9-11,13,24,33H,5-8H2	PBJNYJLKFRLXQN-UHFFFAOYSA-N	315694	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazine- 3-carbonitrile1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.36 (d, J = 8.7, 1H), 8.13 (d, J = 8.7, 1H),7.86 (d, J = 7.6, 1H), 7.71 (d, J = 9.5, 1H), 7.55(qd, J = 9.4, 2.7, 2H), 7.21 (d, J = 2.3, 1H), 6.96(d, J = 4.9, 1H), 6.43 (d, J = 4.9, 1H), 3.80-3.76(m, 4H), 3.48-3.43 (m, 4H)::US10172859, Example 118::US11065253, Example 118::US9732094, Example 118	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315694&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954940	383542427							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659554	OC(c1ccc(OCC#N)nn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O3/c26-19-13-20(27)18(12-17(19)25(34)21-3-4-23(32-31-21)36-8-5-28)24-16-2-1-15(11-22(16)29-14-30-24)33-6-9-35-10-7-33/h1-4,11-14,25,34H,6-10H2	VMNGDZCHPAYWBU-UHFFFAOYSA-N	315695	(6-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyridazin-3- yl-oxy)acetonitrile1H NMR (400 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.93 (d, J = 7.7, 1H), 7.85 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.60 (dd, J = 9.4, 3.3, 1H),7.54 (dd, J = 9.4, 2.5, 1H), 7.40 (d, J = 9.1, 1H),7.21 (d, J = 2.4, 1H), 6.72 (d, J = 5.0, 1H), 6.28(d, J = 4.8, 1H), 5.38 (s, 2H), 3.81-3.75 (m,::US10172859, Example 119::US11065253, Example 119::US9732094, Example 119	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315695&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292848	383542428							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659556	COc1ccc(cc1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23F2N3O3/c1-33-18-5-2-16(3-6-18)26(32)21-13-20(22(27)14-23(21)28)25-19-7-4-17(12-24(19)29-15-30-25)31-8-10-34-11-9-31/h2-7,12-15,26,32H,8-11H2,1H3	IZHMEJPZUSRPSC-UHFFFAOYSA-N	315696	US10172859, Example 120::US11065253, Example 120::US9732094, Example 120::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- methoxyphenyl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.61-7.47 (m, 3H), 7.36-7.30 (m, 2H),7.27 (t, J = 9.1, 1H), 7.20 (d, J = 2.3, 1H), 6.93-6.87 (m, 2H), 6.18 (d, J = 4.6, 1H), 6.14 (d,J = 4.6, 1H), 3.81-3.75 (m, 4H), 3.73 (s, 3H),3.48-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315696&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696345	383542429							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659558	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(OC(F)F)nn1	InChI=1S/C24H20F3N5O3/c25-18-4-1-14(23(33)19-5-6-21(31-30-19)35-24(26)27)11-17(18)22-16-3-2-15(12-20(16)28-13-29-22)32-7-9-34-10-8-32/h1-6,11-13,23-24,33H,7-10H2	RFKLNHCZEVTKQI-UHFFFAOYSA-N	315697	(6-Difluoro- methoxy- pyridazin-3-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.96 (d, J = 9.1, 1H), 7.73-7.63 (m, 2H),7.57-7.47 (m, 3H), 7.46-7.31 (m, 1H), 7.22-7.16 (m, 1H), 6.63 (d, J = 4.4, 1H), 6.10 (d,J = 4.4, 1H), 3.81-3.75 (m, 4H), 3.47-3.41(m, 4H)::US10172859, Example 121::US11065253, Example 121::US9732094, Example 121	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315697&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696306	383542430							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659560	COc1ccc(nn1)C(O)(C#C)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H21ClFN5O3/c1-3-26(34,23-6-7-24(35-2)32-31-23)19-13-18(21(28)14-20(19)27)25-17-5-4-16(12-22(17)29-15-30-25)33-8-10-36-11-9-33/h1,4-7,12-15,34H,8-11H2,2H3	JGPODTAIHNTKRI-UHFFFAOYSA-N	315698	1-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-(6- methoxy- pyridazin-3-yl)- prop-2-yn-1-ol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.28 (d, J = 7.7, 1H), 7.96 (d, J = 9.2, 1H),7.69-7.63 (m, 2H), 7.59 (dd, J = 9.5, 2.5, 1H),7.50 (s, 1H), 7.30 (d, J = 9.2, 1H), 7.23 (d,J = 2.5, 1H), 4.02 (s, 3H), 3.94 (s, 1H), 3.81-3.76 (m, 4H), 3.50-3.44 (m, 4H)::US10172859, Example 122::US11065253, Example 122::US9732094, Example 122	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315698&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696299	383542431							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659562	COc1ccc(nn1)C(O)(C(F)F)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClF3N5O3/c1-36-22-5-4-21(32-33-22)25(35,24(28)29)17-11-16(19(27)12-18(17)26)23-15-3-2-14(10-20(15)30-13-31-23)34-6-8-37-9-7-34/h2-5,10-13,24,35H,6-9H2,1H3	BKJXFQFDFKAFDJ-UHFFFAOYSA-N	315699	1-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2,2- difluoro-1-(6- methoxy- pyridazin-3-yl)- ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.15 (s,1H), 8.17 (d, J = 7.7, 1H), 7.67-7.61 (m, 3H),7.57 (dd, J = 9.5, 2.5, 1H), 7.32 (s, 1H), 7.26(d, 1H), 7.25-7.22 (m, 1H), 7.22-6.96 (m,2H), 4.05 (s, 3H), 3.81-3.75 (m, 4H), 3.50-3.45 (m, 4H).::US10172859, Example 123::US11065253, Example 123::US9732094, Example 123	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315699&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954917	383542432							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659564	COc1ccc(C(O)c2cc(c(F)cc2F)-c2ncnc3cc(ccc23)N2CCOCC2)c(F)c1	InChI=1S/C26H22F3N3O3/c1-34-16-3-5-17(21(27)11-16)26(33)20-12-19(22(28)13-23(20)29)25-18-4-2-15(10-24(18)30-14-31-25)32-6-8-35-9-7-32/h2-5,10-14,26,33H,6-9H2,1H3	DRCQLIDBEVYMKC-UHFFFAOYSA-N	315700	US10172859, Example 124::US11065253, Example 124::US9732094, Example 124::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(2-fluoro- 4-methoxy- phenyl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.70 (t, J = 8.8, 1H), 7.62-7.44 (m, 3H),7.25 (t, J = 9.2, 1H), 7.20 (d, J = 2.4, 1H), 6.82(dd, J = 8.6, 2.5, 1H), 6.74 (dd, J = 12.6, 2.5,1H), 6.34 (d, J = 4.6, 1H), 6.28 (d, J = 4.6, 1H),3.82-3.71 (m, 7H), 3.49-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315700&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966369	383542433							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659566	COc1ccc(nn1)C(C)(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClFN5O3/c1-25(33,22-5-6-23(34-2)31-30-22)18-12-17(20(27)13-19(18)26)24-16-4-3-15(11-21(16)28-14-29-24)32-7-9-35-10-8-32/h3-6,11-14,33H,7-10H2,1-2H3	UAARYCWPHSSNIM-UHFFFAOYSA-N	315701	1-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-(6- methoxy- pyridazin-3-yl)- ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.15 (s,1H), 8.20 (d, J = 7.9, 1H), 7.67 (dd, J = 9.4, 3.4,1H), 7.60-7.54 (m, 3H), 7.23 (d, J = 2.5, 1H),7.18 (d, J = 9.2, 1H), 6.39 (s, 1H), 4.03 (s, 3H),3.82-3.75 (m, 4H), 3.49-3.45 (m, 4H), 2.02(s, 3H)::US10172859, Example 125::US11065253, Example 125::US9732094, Example 125	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315701&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954946	383542434							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659568	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c1-31-18-3-2-16(27-28-18)21(30)12-8-13(15(24)9-14(12)23)20-22-17(25-11-26-20)10-19(33-22)29-4-6-32-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	PIPPQGLJMKVPBT-UHFFFAOYSA-N	315702	US10172859, Example 126::US10172859, Example 127::US10172859, Example 128::US11065253, Example 128::US9732094, Example 128::[2-Chloro-4-fluoro- 5-(6-morpholin-4- ylthieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 8.90 (s,1H), 8.00 (d, J = 7.9, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 10.0, 1H), 7.22 (d, J = 9.2, 1H), 6.62(d, J = 4.9, 1H), 6.54 (s, 1H), 6.22 (d, J = 4.9,1H), 3.99 (s, 3H), 3.77-3.72 (m, 4H), 3.45-3.39 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315702&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966370	383542435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659570	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c1-31-18-3-2-16(27-28-18)21(30)12-8-13(15(24)9-14(12)23)20-22-17(25-11-26-20)10-19(33-22)29-4-6-32-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	PIPPQGLJMKVPBT-UHFFFAOYSA-N	315702	US10172859, Example 126::US10172859, Example 127::US10172859, Example 128::US11065253, Example 128::US9732094, Example 128::[2-Chloro-4-fluoro- 5-(6-morpholin-4- ylthieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 8.90 (s,1H), 8.00 (d, J = 7.9, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 10.0, 1H), 7.22 (d, J = 9.2, 1H), 6.62(d, J = 4.9, 1H), 6.54 (s, 1H), 6.22 (d, J = 4.9,1H), 3.99 (s, 3H), 3.77-3.72 (m, 4H), 3.45-3.39 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315702&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966370	383542435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659572	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c1-31-18-3-2-16(27-28-18)21(30)12-8-13(15(24)9-14(12)23)20-22-17(25-11-26-20)10-19(33-22)29-4-6-32-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	PIPPQGLJMKVPBT-UHFFFAOYSA-N	315702	US10172859, Example 126::US10172859, Example 127::US10172859, Example 128::US11065253, Example 128::US9732094, Example 128::[2-Chloro-4-fluoro- 5-(6-morpholin-4- ylthieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)1H NMR (500 MHz, DMSO-d6) ppm = 8.90 (s,1H), 8.00 (d, J = 7.9, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 10.0, 1H), 7.22 (d, J = 9.2, 1H), 6.62(d, J = 4.9, 1H), 6.54 (s, 1H), 6.22 (d, J = 4.9,1H), 3.99 (s, 3H), 3.77-3.72 (m, 4H), 3.45-3.39 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315702&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966370	383542435							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659574	COc1ccc(nn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-20(29-30-22)24(32)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	FWMURCSQJAVESQ-UHFFFAOYSA-N	315707	US10172859, Example 130::US10172859, Example 131::US11065253, Example 131::US9732094, Example 131::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315707&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954810	383542438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659576	COc1ccc(nn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-20(29-30-22)24(32)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	FWMURCSQJAVESQ-UHFFFAOYSA-N	315707	US10172859, Example 130::US10172859, Example 131::US11065253, Example 131::US9732094, Example 131::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315707&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954810	383542438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659578	COc1ccc(nn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-20(29-30-22)24(32)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	FWMURCSQJAVESQ-UHFFFAOYSA-N	315707	US10172859, Example 130::US10172859, Example 131::US11065253, Example 131::US9732094, Example 131::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315707&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954810	383542438							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659580	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1nc(Cl)nc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20Cl2FN5O3/c1-34-21-5-4-19(30-31-21)23(33)15-11-16(18(27)12-17(15)25)22-14-3-2-13(32-6-8-35-9-7-32)10-20(14)28-24(26)29-22/h2-5,10-12,23,33H,6-9H2,1H3	ULPNOVCLDUJYMN-UHFFFAOYSA-N	315711	US10172859, Example 132::US11065253, Example 132::US9732094, Example 132::[2-Chloro-5-(2- chloro-7- morpholin-4-yl- quinazolin-4-yl)-4- fluorophenyl]-(6- methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 7.94 (d,J = 7.7, 1H), 7.72-7.65 (m, 2H), 7.63-7.49(m, 2H), 7.21 (d, J = 9.1, 1H), 7.15 (d, J = 2.4,1H), 6.22 (s, 1H), 4.00 (s, 3H), 3.79-3.73(m, 4H), 3.53-3.47 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315711&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966371	383542441							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659582	CN(C)CCOc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H29FN6O3/c1-33(2)9-14-37-25-8-7-23(31-32-25)27(35)18-3-6-22(28)21(15-18)26-20-5-4-19(16-24(20)29-17-30-26)34-10-12-36-13-11-34/h3-8,15-17,27,35H,9-14H2,1-2H3	XHNGNRHWZGKQQA-UHFFFAOYSA-N	315712	US10172859, Example 133::US11065253, Example 133::US9732094, Example 133::[6-(2-Dimethyl- amino-ethoxy)- pyridazin-3-yl]-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.69 (d, J = 9.2, 1H), 7.67-7.61 (m, 2H),7.55-7.47 (m, 2H), 7.44-7.36 (m, 1H), 7.24-7.15 (m, 2H), 6.49 (d, J = 4.0, 1H), 6.04-5.98 (m, 1H), 4.56-4.41 (m, 2H), 3.80-3.74(m, 4H), 3.47-3.41 (m, 4H), 2.64 (t, J = 5.8,2H), 2.19 (s, 6H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315712&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954921	383542442							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659584	CCOc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O3/c1-2-34-23-8-7-21(29-30-23)25(32)16-3-6-20(26)19(13-16)24-18-5-4-17(14-22(18)27-15-28-24)31-9-11-33-12-10-31/h3-8,13-15,25,32H,2,9-12H2,1H3	LEDWCZDSFAXZKY-UHFFFAOYSA-N	315713	(6-Ethoxy- pyridazin-3-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.68 (d, J = 9.2, 1H), 7.66-7.61 (m, 2H),7.53-7.50 (m, 2H), 7.43-7.35 (m, 1H), 7.21-7.19 (m, 1H), 7.17 (d, J = 9.1, 1H), 6.47 (d,J = 4.4, 1H), 6.01 (d, J = 4.3, 1H), 4.52-4.38(m, 2H), 3.82-3.73 (m, 4H), 3.46-3.41 (m,4H), 1.36 (t, J = 7.0, 3H)::US10172859, Example 134::US11065253, Example 134::US9732094, Example 134	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315713&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954942	383542443							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659586	COc1ccc(nn1)[C@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m1/s1	MOWXJLUYGFNTAL-XMMPIXPASA-N	315714	(R)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.67 (d, J = 9.5, 1H), 7.62-7.51 (m, 2H), 7.24-7.18 (m, 2H), 6.61 (d, J = 4.8, 1H), 6.23 (d,J = 4.8, 1H), 4.00 (s, 3H), 3.81-3.75 (m, 4H),3.48-3.42 (m, 4H)::US10172859, Example 135::US11065253, Example 135::US9732094, Example 135	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315714&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955008	383542444							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659588	COc1ccc(nn1)[C@@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m0/s1	MOWXJLUYGFNTAL-DEOSSOPVSA-N	315715	(S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91 (d, J = 7.7, 1H), 7.69 (d, J = 9.2, 1H),7.66 (d, J = 9.5, 1H), 7.61-7.52 (m, 2H), 7.24-7.19 (m, 2H), 6.61 (d, J = 5.0, 1H), 6.23 (d,J = 4.9, 1H), 4.00 (s, 3H), 3.81-3.75 (m, 4H),3.48-3.43 (m, 4H)::US10172859, Example 136::US11065253, Example 136::US9732094, Example 136	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315715&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	1IX	7Z88,7Z87,7OTY	86292849	383542445							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659590	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 129::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::US10172859, Example 244::US10172859, Example 262::US11065253, Example 262::US9732094, Example 262::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	1IX	7Z88,7Z87,7OTY	117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659592	CC(O)(c1nccs1)c1cncc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H21N5O2S/c1-22(28,21-24-4-9-30-21)16-10-15(12-23-13-16)20-18-3-2-17(11-19(18)25-14-26-20)27-5-7-29-8-6-27/h2-4,9-14,28H,5-8H2,1H3	WZGXFUTUWYUZBK-UHFFFAOYSA-N	315717	1-[5-(7-Morpholin-4-ylquinazolin-4-yl)pyridin-3-yl]-1-thiazol-2-ylethanol (EXAMPLE 138)::US10172859, Example 138::US10172859, Example 151::US10172859, Example 152::US11065253, Example 152::US9732094, Example 152	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315717&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696290	383542446							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659594	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)C1=CCOCC1	InChI=1S/C23H18FN3O2S/c24-19-4-2-16(22(28)23-25-7-10-30-23)11-18(19)21-17-3-1-15(12-20(17)26-13-27-21)14-5-8-29-9-6-14/h1-5,7,10-13,22,28H,6,8-9H2	PNOUMLBQVUAYPF-UHFFFAOYSA-N	315718	US10172859, Example 139::US11065253, Example 139::US9732094, Example 139::{3-[7-(3,6-Dihydro-2H-pyran-4-yl)quinazolin-4-yl]-4-fluorophenyl}thiazol-2-ylmethanol 	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315718&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696701	383542447							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659596	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-16-2-1-13(20(28)21-23-3-8-30-21)9-14(16)19-15-11-24-18(10-17(15)25-12-26-19)27-4-6-29-7-5-27/h1-3,8-12,20,28H,4-7H2	XCXKEQWXYBNSEE-UHFFFAOYSA-N	315719	US10172859, Example 140::US11065253, Example 140::US9732094, Example 140::[4-Fluoro-3-(7-morpholin-4-ylpyrido[4,3-d}pyrimidin-4-yl)phenyl]thiazol-2-ylmethanol 	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315719&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696258	383542448							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659598	OCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H19ClFN5O3S/c23-16-6-17(24)14(5-13(16)21(31)22-28-12(9-30)10-33-22)20-15-8-25-19(7-18(15)26-11-27-20)29-1-3-32-4-2-29/h5-8,10-11,21,30-31H,1-4,9H2	ZUENLBQQNMTFPU-UHFFFAOYSA-N	315720	US10172859, Example 141::US11065253, Example 141::US9732094, Example 141::[2-Chloro-4-fluoro-5-(7-morpholin-4-ylpyrido[4,3-d}pyrimidin-4-yl)phenyl]-(4-hydroxymethylthiazol-2-yl)methanol 	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315720&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696307	383542449							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659600	OCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN4O3S/c24-18-9-19(25)17(8-16(18)22(31)23-28-13(10-30)11-33-23)21-15-2-1-14(7-20(15)26-12-27-21)29-3-5-32-6-4-29/h1-2,7-9,11-12,22,30-31H,3-6,10H2	FTJCWHDAYCNQKH-UHFFFAOYSA-N	315721	US10172859, Example 142::US11065253, Example 142::US9732094, Example 142::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- hydroxymethyl- thiazol-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.75-7.69 (m, 2H), 7.59-7.49 (m, 2H),7.36 (t, J = 1.1, 1H), 7.23-7.17 (m, 1H), 7.00(d, J = 5.1, 1H), 6.27 (d, J = 5.0, 1H), 5.24 (t,J = 5.7, 1H), 4.52-4.45 (m, 2H), 3.81-3.74 (m,4H), 3.49-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315721&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954746	383542450							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659602	CNCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23ClFN5O2S/c1-27-11-14-12-34-24(30-14)23(32)17-9-18(20(26)10-19(17)25)22-16-3-2-15(8-21(16)28-13-29-22)31-4-6-33-7-5-31/h2-3,8-10,12-13,23,27,32H,4-7,11H2,1H3	RAMIQEMCKWWMBT-UHFFFAOYSA-N	315722	US10172859, Example 143::US11065253, Example 143::US9732094, Example 143::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- methylaminomethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.26 (s, 1H), 7.76-7.69 (m, 2H), 7.58-7.50 (m, 2H), 7.48-7.43 (m, 1H), 7.24-7.16(m, 1H), 6.97 (s, 1H), 6.28 (s, 1H), 3.80 (s,2H), 3.79-3.74 (m, 4H), 3.48-3.42 (m, 4H),2.33 (s, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315722&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696327	383542451							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659604	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C20H17FN4O2S2/c21-14-2-1-12(18(26)20-22-3-8-28-20)9-13(14)17-19-15(23-11-24-17)10-16(29-19)25-4-6-27-7-5-25/h1-3,8-11,18,26H,4-7H2	AIDFNPQAXSJWSH-UHFFFAOYSA-N	315723	US10172859, Example 144::US10172859, Example 145::US10172859, Example 146::US11065253, Example 146::US9732094, Example 146::[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]thiazol-2- yl-methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.76 (dd, J = 7.0, 2.3, 1H), 7.73 (d, J = 3.2,1H), 7.69-7.64 (m, 2H), 7.43-7.38 (m, 1H),6.96 (d, J = 4.6, 1H), 6.53 (s, 1H), 6.07 (d,J = 4.6, 1H), 3.77-3.71 (m, 4H), 3.44-3.38 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315723&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696438	383542452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659606	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C20H17FN4O2S2/c21-14-2-1-12(18(26)20-22-3-8-28-20)9-13(14)17-19-15(23-11-24-17)10-16(29-19)25-4-6-27-7-5-25/h1-3,8-11,18,26H,4-7H2	AIDFNPQAXSJWSH-UHFFFAOYSA-N	315723	US10172859, Example 144::US10172859, Example 145::US10172859, Example 146::US11065253, Example 146::US9732094, Example 146::[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]thiazol-2- yl-methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.76 (dd, J = 7.0, 2.3, 1H), 7.73 (d, J = 3.2,1H), 7.69-7.64 (m, 2H), 7.43-7.38 (m, 1H),6.96 (d, J = 4.6, 1H), 6.53 (s, 1H), 6.07 (d,J = 4.6, 1H), 3.77-3.71 (m, 4H), 3.44-3.38 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315723&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696438	383542452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659608	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C20H17FN4O2S2/c21-14-2-1-12(18(26)20-22-3-8-28-20)9-13(14)17-19-15(23-11-24-17)10-16(29-19)25-4-6-27-7-5-25/h1-3,8-11,18,26H,4-7H2	AIDFNPQAXSJWSH-UHFFFAOYSA-N	315723	US10172859, Example 144::US10172859, Example 145::US10172859, Example 146::US11065253, Example 146::US9732094, Example 146::[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]thiazol-2- yl-methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.76 (dd, J = 7.0, 2.3, 1H), 7.73 (d, J = 3.2,1H), 7.69-7.64 (m, 2H), 7.43-7.38 (m, 1H),6.96 (d, J = 4.6, 1H), 6.53 (s, 1H), 6.07 (d,J = 4.6, 1H), 3.77-3.71 (m, 4H), 3.44-3.38 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315723&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696438	383542452							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659610	OC(c1ccc(s1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccs1	InChI=1S/C20H18N4O2S2/c25-19(20-21-5-10-27-20)17-4-3-16(28-17)18-14-2-1-13(11-15(14)22-12-23-18)24-6-8-26-9-7-24/h1-5,10-12,19,25H,6-9H2	VURHFAWQGNOLNC-UHFFFAOYSA-N	315726	US10172859, Example 147::US10172859, Example 160::US10172859, Example 161::US11065253, Example 161::US9732094, Example 147::[5-(7-Morpholin-4- ylquinazolin-4-yl)- thiophen-2-yl]- thiazol-2-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 8.93 (s,1H), 8.34 (d, J = 9.5, 1H), 7.83 (d, J = 3.9, 1H),7.79 (d, J = 3.2, 1H), 7.71 (d, J = 3.2, 1H), 7.56(dd, J = 9.5, 2.7, 1H), 7.32 (d, J = 4.8, 1H), 7.26-7.24 (m, 1H), 7.16 (d, J = 2.6, 1H), 6.31-6.29(m, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315726&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954835	383542453							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659612	OC(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H20N4O2S/c27-21(22-23-6-11-29-22)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)24-14-25-20)26-7-9-28-10-8-26/h1-6,11-14,21,27H,7-10H2	ICUMGURWJXOHLQ-UHFFFAOYSA-N	315727	US10172859, Example 148::US10172859, Example 149::US10172859, Example 150::US11065253, Example 150::US9732094, Example 150::[3-(7-Morpholin-4- ylquinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.86 (d, J = 9.4, 1H), 7.83-7.81 (m, 1H),7.74 (d, J = 3.2, 1H), 7.68-7.64 (m, 3H), 7.59-7.55 (m, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.20(d, J = 2.6, 1H), 6.93 (d, J = 4.5, 1H), 6.10 (d,J = 4.0, 1H), 3.80-3.76 (m, 4H), 3.46-3.42 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315727&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954926	383542454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659614	OC(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H20N4O2S/c27-21(22-23-6-11-29-22)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)24-14-25-20)26-7-9-28-10-8-26/h1-6,11-14,21,27H,7-10H2	ICUMGURWJXOHLQ-UHFFFAOYSA-N	315727	US10172859, Example 148::US10172859, Example 149::US10172859, Example 150::US11065253, Example 150::US9732094, Example 150::[3-(7-Morpholin-4- ylquinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.86 (d, J = 9.4, 1H), 7.83-7.81 (m, 1H),7.74 (d, J = 3.2, 1H), 7.68-7.64 (m, 3H), 7.59-7.55 (m, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.20(d, J = 2.6, 1H), 6.93 (d, J = 4.5, 1H), 6.10 (d,J = 4.0, 1H), 3.80-3.76 (m, 4H), 3.46-3.42 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315727&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954926	383542454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659616	OC(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H20N4O2S/c27-21(22-23-6-11-29-22)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)24-14-25-20)26-7-9-28-10-8-26/h1-6,11-14,21,27H,7-10H2	ICUMGURWJXOHLQ-UHFFFAOYSA-N	315727	US10172859, Example 148::US10172859, Example 149::US10172859, Example 150::US11065253, Example 150::US9732094, Example 150::[3-(7-Morpholin-4- ylquinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.86 (d, J = 9.4, 1H), 7.83-7.81 (m, 1H),7.74 (d, J = 3.2, 1H), 7.68-7.64 (m, 3H), 7.59-7.55 (m, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.20(d, J = 2.6, 1H), 6.93 (d, J = 4.5, 1H), 6.10 (d,J = 4.0, 1H), 3.80-3.76 (m, 4H), 3.46-3.42 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315727&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954926	383542454							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659618	CC(O)(c1nccs1)c1cncc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H21N5O2S/c1-22(28,21-24-4-9-30-21)16-10-15(12-23-13-16)20-18-3-2-17(11-19(18)25-14-26-20)27-5-7-29-8-6-27/h2-4,9-14,28H,5-8H2,1H3	WZGXFUTUWYUZBK-UHFFFAOYSA-N	315717	1-[5-(7-Morpholin-4-ylquinazolin-4-yl)pyridin-3-yl]-1-thiazol-2-ylethanol (EXAMPLE 138)::US10172859, Example 138::US10172859, Example 151::US10172859, Example 152::US11065253, Example 152::US9732094, Example 152	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315717&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696290	383542446							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659620	CC(O)(c1nccs1)c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22N4O2S/c1-23(28,22-24-7-12-30-22)17-4-2-3-16(13-17)21-19-6-5-18(14-20(19)25-15-26-21)27-8-10-29-11-9-27/h2-7,12-15,28H,8-11H2,1H3	BFPJNIQERRPKOK-UHFFFAOYSA-N	315733	1-[3-(7-Morpholin- 4-ylquinazolin-4-yl)- phenyl]-1-thiazol-2- ylethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.96-7.93 (m, 1H), 7.83 (d, J = 9.4, 1H),7.79-7.76 (m, 1H), 7.74 (d, J = 3.2, 1H), 7.63-7.61 (m, 1H), 7.60 (d, J = 3.3, 1H), 7.55 (d,J = 7.7, 1H), 7.53-7.50 (m, 1H), 7.20 (d, J = 2.6,1H), 6.82 (s, 1H), 3.81-3.75 (m, 4H), 3.47-3.42 (m, 4H), 1.98 (s, 3H)::US10172859, Example 154::US11065253, Example 154::US9732094, Example 154	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315733&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711769	383542456							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659622	OC(c1nccs1)(c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1)C(F)(F)F	InChI=1S/C23H19F3N4O2S/c24-23(25,26)22(31,21-27-6-11-33-21)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)28-14-29-20)30-7-9-32-10-8-30/h1-6,11-14,31H,7-10H2	QOLLQIBBKMYYHN-UHFFFAOYSA-N	315738	2,2,2-Trifluoro-1-[3- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-thiazol-2- ylethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.54 (s, 1H), 8.15-8.13 (m, 1H), 7.98-7.95 (m, 1H), 7.94 (d, J = 3.3, 1H), 7.87 (d,J = 3.2, 1H), 7.83-7.79 (m, 2H), 7.67 (t, J = 7.8,1H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.21 (d, J = 2.6,1H), 3.80-3.76 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 159::US10172859, Example 172::US10172859, Example 173::US11065253, Example 173::US9732094, Example 173	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315738&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711794	383542459							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659624	CC(O)(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-23(29,22-25-6-11-31-22)15-2-5-19(24)18(12-15)21-17-4-3-16(13-20(17)26-14-27-21)28-7-9-30-10-8-28/h2-6,11-14,29H,7-10H2,1H3	WUOHIOVTQJRGGL-UHFFFAOYSA-N	315742	1-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-thiazol- 2-ylethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.82-7.75 (m, 2H), 7.73 (d, J = 3.2, 1H),7.61 (d, J = 3.2, 1H), 7.53-7.50 (m, 2H), 7.41-7.36 (m, 1H), 7.20 (d, J = 1.9, 1H), 6.90 (s, 1H),3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H), 1.95(s, 3H)::US10172859, Example 163::US11065253, Example 163::US9732094, Example 163	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315742&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711799	383542461							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659628	OC(c1nccs1)c1cc(F)c(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H18F2N4O2S/c23-17-10-13(21(29)22-25-3-8-31-22)9-16(19(17)24)20-15-2-1-14(11-18(15)26-12-27-20)28-4-6-30-7-5-28/h1-3,8-12,21,29H,4-7H2	YYXOQNNOPYQUJY-UHFFFAOYSA-N	315750	US10172859, Example 171::US10172859, Example 178::US10172859, Example 179::US11065253, Example 179::US9732094, Example 179::[3,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.75 (d, J = 3.2, 1H), 7.72-7.66 (m, 2H),7.61-7.57 (m, 1H), 7.56-7.49 (m, 2H), 7.21(d, J = 2.4, 1H), 7.10 (d, J = 4.8, 1H), 6.10 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954936	383542465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659631	OC(c1nccs1)(c1cccc(c1)-c1ncnc2cc(ccc12)N1CCOCC1)C(F)(F)F	InChI=1S/C23H19F3N4O2S/c24-23(25,26)22(31,21-27-6-11-33-21)16-3-1-2-15(12-16)20-18-5-4-17(13-19(18)28-14-29-20)30-7-9-32-10-8-30/h1-6,11-14,31H,7-10H2	QOLLQIBBKMYYHN-UHFFFAOYSA-N	315738	2,2,2-Trifluoro-1-[3- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-1-thiazol-2- ylethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.54 (s, 1H), 8.15-8.13 (m, 1H), 7.98-7.95 (m, 1H), 7.94 (d, J = 3.3, 1H), 7.87 (d,J = 3.2, 1H), 7.83-7.79 (m, 2H), 7.67 (t, J = 7.8,1H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.21 (d, J = 2.6,1H), 3.80-3.76 (m, 4H), 3.47-3.43 (m, 4H)::US10172859, Example 159::US10172859, Example 172::US10172859, Example 173::US11065253, Example 173::US9732094, Example 173	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315738&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711794	383542459							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659634	COC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-29-22(23-25-6-11-31-23)15-2-5-19(24)18(12-15)21-17-4-3-16(13-20(17)26-14-27-21)28-7-9-30-10-8-28/h2-6,11-14,22H,7-10H2,1H3	KITWWWFLDQOYEC-UHFFFAOYSA-N	315754	4-[2-Fluoro-5- (methoxy-thiazol-2- ylmethyl)phenyl]-7- morpholin-4-yl- quinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.78 (d, J = 3.2, 1H), 7.73 (d, J = 3.2, 1H),7.67-7.62 (m, 2H), 7.54-7.52 (m, 2H), 7.49-7.44 (m, 1H), 7.21-7.19 (m, 1H), 5.84 (s, 1H),3.80-3.75 (m, 4H), 3.46-3.43 (m, 4H), 3.43(s, 3H)::US10172859, Example 175::US10172859, Example 176::US10172859, Example 177::US11065253, Example 177::US9732094, Example 177	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315754&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954858	383542467							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659636	OC(c1nccs1)c1cc(F)c(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H18F2N4O2S/c23-17-10-13(21(29)22-25-3-8-31-22)9-16(19(17)24)20-15-2-1-14(11-18(15)26-12-27-20)28-4-6-30-7-5-28/h1-3,8-12,21,29H,4-7H2	YYXOQNNOPYQUJY-UHFFFAOYSA-N	315750	US10172859, Example 171::US10172859, Example 178::US10172859, Example 179::US11065253, Example 179::US9732094, Example 179::[3,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.75 (d, J = 3.2, 1H), 7.72-7.66 (m, 2H),7.61-7.57 (m, 1H), 7.56-7.49 (m, 2H), 7.21(d, J = 2.4, 1H), 7.10 (d, J = 4.8, 1H), 6.10 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954936	383542465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659638	OC(c1nccs1)c1cc(F)c(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H18F2N4O2S/c23-17-10-13(21(29)22-25-3-8-31-22)9-16(19(17)24)20-15-2-1-14(11-18(15)26-12-27-20)28-4-6-30-7-5-28/h1-3,8-12,21,29H,4-7H2	YYXOQNNOPYQUJY-UHFFFAOYSA-N	315750	US10172859, Example 171::US10172859, Example 178::US10172859, Example 179::US11065253, Example 179::US9732094, Example 179::[3,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.75 (d, J = 3.2, 1H), 7.72-7.66 (m, 2H),7.61-7.57 (m, 1H), 7.56-7.49 (m, 2H), 7.21(d, J = 2.4, 1H), 7.10 (d, J = 4.8, 1H), 6.10 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.48-3.43 (m,4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315750&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954936	383542465							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659640	OC(c1nccs1)c1cnc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-20-16(9-13(11-24-20)19(28)21-23-3-8-30-21)18-15-2-1-14(10-17(15)25-12-26-18)27-4-6-29-7-5-27/h1-3,8-12,19,28H,4-7H2	HORBNTVKYAVYTP-UHFFFAOYSA-N	315759	US10172859, Example 180::US10172859, Example 188::US10172859, Example 189::US11065253, Example 189::US9732094, Example 189::[6-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]thiazol- 2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56-8.52 (m, 1H), 8.21 (dd, J = 9.0, 2.3,1H), 7.77 (d, J = 3.2, 1H), 7.69 (d, J = 3.2, 1H),7.59-7.52 (m, 2H), 7.23-7.20 (m, 1H), 7.18(d, J = 4.7, 1H), 6.23 (d, J = 4.5, 1H), 3.82-3.73(m, 4H), 3.50-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954807	383542468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659642	Cc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN4O2S/c1-13-11-32-23(28-13)22(30)16-9-17(19(25)10-18(16)24)21-15-3-2-14(8-20(15)26-12-27-21)29-4-6-31-7-5-29/h2-3,8-12,22,30H,4-7H2,1H3	ZNMXTDAANBXETP-UHFFFAOYSA-N	315760	US10172859, Example 181::US11065253, Example 181::US9732094, Example 181::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4-methyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.73 (dd, J = 10.5, 8.6, 2H), 7.57-7.51 (m,2H), 7.22-7.18 (m, 2H), 6.97 (s, 1H), 6.26 (s,1H), 3.80-3.74 (m, 4H), 3.49-3.41 (m, 4H),2.30 (d, J = 1.0, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315760&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954774	383542469							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659645	OCc1csc(n1)[C@@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN4O3S/c24-18-9-19(25)17(8-16(18)22(31)23-28-13(10-30)11-33-23)21-15-2-1-14(7-20(15)26-12-27-21)29-3-5-32-6-4-29/h1-2,7-9,11-12,22,30-31H,3-6,10H2/t22-/m0/s1	FTJCWHDAYCNQKH-QFIPXVFZSA-N	315764	(S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- hydroxymethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.73 (dd, J = 8.6, 4.8, 2H), 7.58-7.50 (m,2H), 7.39-7.34 (m, 1H), 7.22-7.18 (m, 1H),7.02 (d, J = 5.0, 1H), 6.27 (d, J = 5.0, 1H), 5.27(t, J = 5.7, 1H), 4.51-4.47 (m, 2H), 3.80-3.74(m, 4H), 3.48-3.40 (m, 4H)::US10172859, Example 185::US11065253, Example 185::US9732094, Example 185	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315764	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315764&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954745	383542471							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659647	OCc1csc(n1)[C@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClFN4O3S/c24-18-9-19(25)17(8-16(18)22(31)23-28-13(10-30)11-33-23)21-15-2-1-14(7-20(15)26-12-27-21)29-3-5-32-6-4-29/h1-2,7-9,11-12,22,30-31H,3-6,10H2/t22-/m1/s1	FTJCWHDAYCNQKH-JOCHJYFZSA-N	315765	(R)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4- hydroxymethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.73 (dd, J = 8.6, 4.5, 2H), 7.57-7.52 (m,2H), 7.38-7.35 (m, 1H), 7.22-7.19 (m, 1H),7.03 (d, J = 5.0, 1H), 6.27 (d, J = 5.0, 1H), 5.27(t, J = 5.7, 1H), 4.50-4.46 (m, 2H), 3.80-3.74(m, 4H), 3.48-3.42 (m, 4H)::US10172859, Example 186::US11065253, Example 186::US9732094, Example 186	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315765	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315765&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954897	383542472							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659649	OCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1C2CCC1COC2	InChI=1S/C25H22ClFN4O3S/c26-20-7-21(27)19(6-18(20)24(33)25-30-13(8-32)11-35-25)23-17-4-3-14(5-22(17)28-12-29-23)31-15-1-2-16(31)10-34-9-15/h3-7,11-12,15-16,24,32-33H,1-2,8-10H2	VSYCUCYLHGGKPK-UHFFFAOYSA-N	315766	US10172859, Example 187::US11065253, Example 187::US9732094, Example 187::{2-Chloro-4-fluoro- 5-[7-(3-oxa-8-aza- bicyclo[3.2.1]oct-8- yl)quinazolin-4-yl]- phenyl}-(4-hydroxy- methylthiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.03 (s,1H), 7.71 (t, J = 8.5, 2H), 7.50 (dd, J = 9.3, 3.2,1H), 7.40 (dd, J = 9.4, 2.5, 1H), 7.37-7.35 (m,1H), 7.13 (d, J = 2.4, 1H), 7.01 (d, J = 5.1, 1H),6.27 (d, J = 5.0, 1H), 5.26 (t, J = 5.7, 1H), 4.52-4.50 (m, 2H), 4.50-4.47 (m, 2H), 3.69 (d,J = 10.9, 2H), 3.57-3.50 (m, 2H), 2.09-1.94(m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315766&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954749	383542473							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659651	OC(c1nccs1)c1cnc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-20-16(9-13(11-24-20)19(28)21-23-3-8-30-21)18-15-2-1-14(10-17(15)25-12-26-18)27-4-6-29-7-5-27/h1-3,8-12,19,28H,4-7H2	HORBNTVKYAVYTP-UHFFFAOYSA-N	315759	US10172859, Example 180::US10172859, Example 188::US10172859, Example 189::US11065253, Example 189::US9732094, Example 189::[6-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]thiazol- 2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56-8.52 (m, 1H), 8.21 (dd, J = 9.0, 2.3,1H), 7.77 (d, J = 3.2, 1H), 7.69 (d, J = 3.2, 1H),7.59-7.52 (m, 2H), 7.23-7.20 (m, 1H), 7.18(d, J = 4.7, 1H), 6.23 (d, J = 4.5, 1H), 3.82-3.73(m, 4H), 3.50-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954807	383542468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659653	OC(c1nccs1)c1cnc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C21H18FN5O2S/c22-20-16(9-13(11-24-20)19(28)21-23-3-8-30-21)18-15-2-1-14(10-17(15)25-12-26-18)27-4-6-29-7-5-27/h1-3,8-12,19,28H,4-7H2	HORBNTVKYAVYTP-UHFFFAOYSA-N	315759	US10172859, Example 180::US10172859, Example 188::US10172859, Example 189::US11065253, Example 189::US9732094, Example 189::[6-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]thiazol- 2-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56-8.52 (m, 1H), 8.21 (dd, J = 9.0, 2.3,1H), 7.77 (d, J = 3.2, 1H), 7.69 (d, J = 3.2, 1H),7.59-7.52 (m, 2H), 7.23-7.20 (m, 1H), 7.18(d, J = 4.7, 1H), 6.23 (d, J = 4.5, 1H), 3.82-3.73(m, 4H), 3.50-3.42 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315759&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954807	383542468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659655	CCNCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25ClFN5O2S/c1-2-28-12-15-13-35-25(31-15)24(33)18-10-19(21(27)11-20(18)26)23-17-4-3-16(9-22(17)29-14-30-23)32-5-7-34-8-6-32/h3-4,9-11,13-14,24,28,33H,2,5-8,12H2,1H3	QYNNKWUEYHNEOA-UHFFFAOYSA-N	315769	US10172859, Example 190::US11065253, Example 190::US9732094, Example 190::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4-ethyl- aminomethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.25 (s, 1H), 7.73 (d, J = 1.6, 1H), 7.71 (s,1H), 7.58-7.49 (m, 2H), 7.44-7.40 (m, 1H),7.23-7.18 (m, 1H), 7.05 (s, 1H), 6.27 (s, 1H),3.80-3.76 (m, 6H), 3.48-3.40 (m, 4H), 2.60(q, J = 7.1, 2H), 1.01 (t, J = 7.1, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315769&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954972	383542474							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659657	CCNCc1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H25ClFN5O2S/c1-2-28-12-15-13-35-25(31-15)24(33)18-10-19(21(27)11-20(18)26)23-17-4-3-16(9-22(17)29-14-30-23)32-5-7-34-8-6-32/h3-4,9-11,13-14,24,28,33H,2,5-8,12H2,1H3	QYNNKWUEYHNEOA-UHFFFAOYSA-N	315769	US10172859, Example 190::US11065253, Example 190::US9732094, Example 190::[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(4-ethyl- aminomethyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.25 (s, 1H), 7.73 (d, J = 1.6, 1H), 7.71 (s,1H), 7.58-7.49 (m, 2H), 7.44-7.40 (m, 1H),7.23-7.18 (m, 1H), 7.05 (s, 1H), 6.27 (s, 1H),3.80-3.76 (m, 6H), 3.48-3.40 (m, 4H), 2.60(q, J = 7.1, 2H), 1.01 (t, J = 7.1, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315769&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954972	383542474							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659659	Cn1cc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2/c1-28-13-16(12-27-28)23(30)15-2-5-20(24)19(10-15)22-18-4-3-17(11-21(18)25-14-26-22)29-6-8-31-9-7-29/h2-5,10-14,23,30H,6-9H2,1H3	DLENRIORLMKFNS-UHFFFAOYSA-N	315770	US10172859, Example 191::US11065253, Example 191::US9732094, Example 191::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazol-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.68-7.33 (m, 6H), 7.31-7.15 (m, 2H),5.76 (s, 2H), 3.90-3.64 (m, 7H), 3.51-3.39(m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315770&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954823	383542475							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659661	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)15-7-14(9-25-21(15)23)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	FWJBVJNPRGKVFD-UHFFFAOYSA-N	315771	(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.14 (s,1H), 9.09 (s, 1H), 8.67-8.65 (m, 1H), 8.46(dd, J = 9.0, 2.4, 1H), 7.03-6.99 (m, 2H), 6.11(d, J = 5.2, 1H), 3.77-3.68 (m, 8H), 2.31 (s,3H), 2.19 (s, 3H)::US10172859, Example 192::US11065253, Example 192::US9732094, Example 192	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315771	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315771&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955003	383542476							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659663	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2S/c1-13-14(2)32-23(28-13)21(30)18-9-15(11-25-22(18)24)20-17-4-3-16(10-19(17)26-12-27-20)29-5-7-31-8-6-29/h3-4,9-12,21,30H,5-8H2,1-2H3	JZLKXSPJLMDHOQ-UHFFFAOYSA-N	315772	(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.58-8.56 (m, 1H), 8.37 (dd, J = 9.0, 2.4,1H), 7.87 (d, J = 9.4, 1H), 7.57 (dd, J = 9.4, 2.6,1H), 7.22 (d, J = 2.5, 1H), 6.99 (d, J = 5.1, 1H),6.11 (d, J = 5.1, 1H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H), 2.30 (s, 3H), 2.19 (s, 3H)::US10172859, Example 194::US10172859, Example 205::US10172859, Example 206::US11065253, Example 206::US9732094, Example 206	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954971	383542477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659665	Cc1csc(n1)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C21H19FN6O2S/c1-12-10-31-21(27-12)19(29)13-6-14(20(22)24-8-13)18-15-9-23-17(7-16(15)25-11-26-18)28-2-4-30-5-3-28/h6-11,19,29H,2-5H2,1H3	NVCSVGUFUPGXIG-UHFFFAOYSA-N	315773	US10172859, Example 195::US11065253, Example 195::US9732094, Example 195::[6-Fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]-(4- methyl-thiazol-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.17 (s,1H), 8.90 (d, J = 2.5, 1H), 8.57-8.53 (m, 1H),8.29 (dd, J = 9.1, 2.4, 1H), 7.24-7.21 (m, 1H),7.10 (d, J = 4.9, 1H), 7.00 (s, 1H), 6.16 (d,J = 4.9, 1H), 3.79-3.67 (m, 8H), 2.33 (d, J = 1.0,3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315773&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966380	383542478							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659667	Cc1nc(sc1C)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)14-7-15(21(23)25-9-14)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	CSNOKHOWFALBPK-UHFFFAOYSA-N	315774	(4,5-Dimethyl- thiazol-2-yl)-[6- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.90 (d, J = 2.4, 1H), 8.53 (d, J = 2.3, 1H),8.27 (dd, J = 9.1, 2.4, 1H), 7.06 (d, J = 4.9, 1H),6.99 (s, 1H), 6.08 (d, J = 4.9, 1H), 3.76-3.69(m, 8H), 2.30 (s, 3H), 2.21 (s, 3H)::US10172859, Example 196::US10172859, Example 203::US10172859, Example 204::US11065253, Example 204::US9732094, Example 204	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954852	383542479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659669	CC(C)n1cc(cn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H26FN5O2/c1-16(2)31-14-18(13-29-31)25(32)17-3-6-22(26)21(11-17)24-20-5-4-19(12-23(20)27-15-28-24)30-7-9-33-10-8-30/h3-6,11-16,25,32H,7-10H2,1-2H3	RWAYQUVHYMUCJE-UHFFFAOYSA-N	315775	US10172859, Example 197::US11065253, Example 197::US9732094, Example 197::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1- isopropyl-1H- pyrazol-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.64-7.60 (m, 1H), 7.60-7.57 (m, 2H),7.56-7.50 (m, 2H), 7.41-7.35 (m, 1H), 7.28(s, 1H), 7.20 (d, J = 2.2, 1H), 5.76 (s, 2H), 4.42(h, J = 6.6, 1H), 3.80-3.76 (m, 4H), 3.46-3.42(m, 4H), 1.36 (d, J = 6.7, 6H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315775&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954976	383542480							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659671	CC(C)(C)n1cc(cn1)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H27FN6O2/c1-25(2,3)32-14-17(13-30-32)23(33)20-10-16(12-27-24(20)26)22-19-5-4-18(11-21(19)28-15-29-22)31-6-8-34-9-7-31/h4-5,10-15,23,33H,6-9H2,1-3H3	GJESUBAPEJHPIP-UHFFFAOYSA-N	315776	(1-tert-Butyl-1H- pyrazol-4-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.54-8.49 (m, 1H), 8.46 (dd, J = 9.4, 2.6,1H), 7.89 (d, J = 9.4, 1H), 7.73 (s, 1H), 7.57(dd, J = 9.5, 2.6, 1H), 7.36 (s, 1H), 7.23 (d,J = 2.5, 1H), 6.02 (d, J = 4.8, 1H), 5.95 (d, J =4.6, 1H), 3.82-3.75 (m, 4H), 3.50-3.42 (m, 4H),1.48 (s, 9H)::US10172859, Example 198::US11065253, Example 198::US9732094, Example 198	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315776&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954781	383542481							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659673	FC(F)OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H19F3N4O2S/c24-18-4-1-14(21(32-23(25)26)22-27-5-10-33-22)11-17(18)20-16-3-2-15(12-19(16)28-13-29-20)30-6-8-31-9-7-30/h1-5,10-13,21,23H,6-9H2	OALIVDXCYALUSU-UHFFFAOYSA-N	315777	4-[5-(Difluoro- methoxy-thiazol-2- ylmethyl)-2-fluoro- phenyl]-7- morpholin-4-yl- quinazoline1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.85 (d, J = 3.2, 1H), 7.81 (d, J = 3.2, 1H),7.73-7.71 (m, 2H), 7.55-7.52 (m, 2H), 7.52-7.48 (m, 1H), 7.22-6.82 (m, 3H), 3.80-3.75(m, 4H), 3.48-3.42 (m, 4H)::US10172859, Example 199::US11065253, Example 199::US9732094, Example 199	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315777&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954812	383542482							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659675	Cc1nc(sc1CO)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23FN4O3S/c1-14-21(12-30)33-24(28-14)23(31)15-2-5-19(25)18(10-15)22-17-4-3-16(11-20(17)26-13-27-22)29-6-8-32-9-7-29/h2-5,10-11,13,23,30-31H,6-9,12H2,1H3	ZYEYIBTVJPAKBV-UHFFFAOYSA-N	315778	US10172859, Example 200::US11065253, Example 200::US9732094, Example 200::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-hydroxy- methyl-4-methyl- thiazol-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.70-7.63 (m, 2H), 7.55-7.50 (m, 2H),7.44-7.39 (m, 1H), 7.22-7.19 (m, 1H), 6.81(d, J = 4.5, 1H), 5.95 (d, J = 4.3, 1H), 5.35 (t,J = 5.6, 1H), 4.54 (d, J = 5.4, 2H), 3.80-3.75 (m,4H), 3.47-3.42 (m, 4H), 2.22 (s, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315778&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966381	383542483							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659677	CC(O)c1csc(n1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClFN4O3S/c1-13(31)21-11-34-24(29-21)23(32)16-9-17(19(26)10-18(16)25)22-15-3-2-14(8-20(15)27-12-28-22)30-4-6-33-7-5-30/h2-3,8-13,23,31-32H,4-7H2,1H3	ASWGTDOVISOWCF-UHFFFAOYSA-N	315779	1-(2-{[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}thiazol-4-yl)- ethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11-9.09 (m, 1H), 7.75-7.70 (m, 2H), 7.55-7.52(m, 2H), 7.34-7.32 (m, 1H), 7.21-7.19 (m,1H), 7.00-6.96 (m, 1H), 6.28-6.25 (m, 1H),5.26-5.18 (m, 1H), 4.77-4.70 (m, 1H), 3.79-3.75 (m, 4H), 3.47-3.43 (m, 4H), 1.36-1.30(m, 3H)::US10172859, Example 201::US11065253, Example 201::US9732094, Example 201	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315779&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954894	383542484							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659679	CCn1cc(cn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23ClFN5O2/c1-2-31-13-15(12-29-31)24(32)18-10-19(21(26)11-20(18)25)23-17-4-3-16(9-22(17)27-14-28-23)30-5-7-33-8-6-30/h3-4,9-14,24,32H,2,5-8H2,1H3	QQVCKAJSGSGZCZ-UHFFFAOYSA-N	315780	US10172859, Example 202::US11065253, Example 202::US9732094, Example 202::[2-Chloro-4-fluoro- 5-(7-morpholin-4- ylquinazolin-4-yl)- phenyl]-(1-ethyl- 1H-pyrazol-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.91-7.88 (m, 1H), 7.64 (d, J = 9.6, 1H),7.59 (dd, J = 9.4, 3.2, 1H), 7.57-7.52 (m, 2H),7.29 (s, 1H), 7.22-7.20 (m, 1H), 5.98 (d,J = 4.8, 1H, 5.93 (d, J = 4.8, 1H), 4.08-4.02 (m,2H), 3.80-3.76 (m, 4H), 3.48-3.43 (m, 4H),1.34-1.28 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315780&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966382	383542485							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659681	Cc1nc(sc1C)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)14-7-15(21(23)25-9-14)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	CSNOKHOWFALBPK-UHFFFAOYSA-N	315774	(4,5-Dimethyl- thiazol-2-yl)-[6- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.90 (d, J = 2.4, 1H), 8.53 (d, J = 2.3, 1H),8.27 (dd, J = 9.1, 2.4, 1H), 7.06 (d, J = 4.9, 1H),6.99 (s, 1H), 6.08 (d, J = 4.9, 1H), 3.76-3.69(m, 8H), 2.30 (s, 3H), 2.21 (s, 3H)::US10172859, Example 196::US10172859, Example 203::US10172859, Example 204::US11065253, Example 204::US9732094, Example 204	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954852	383542479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659683	Cc1nc(sc1C)C(O)c1cnc(F)c(c1)-c1ncnc2cc(ncc12)N1CCOCC1	InChI=1S/C22H21FN6O2S/c1-12-13(2)32-22(28-12)20(30)14-7-15(21(23)25-9-14)19-16-10-24-18(8-17(16)26-11-27-19)29-3-5-31-6-4-29/h7-11,20,30H,3-6H2,1-2H3	CSNOKHOWFALBPK-UHFFFAOYSA-N	315774	(4,5-Dimethyl- thiazol-2-yl)-[6- fluoro-5-(7- morpholin-4-yl- pyrido[4,3-d}- pyrimidin-4-yl)- pyridin-3-yl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.16 (s,1H), 8.90 (d, J = 2.4, 1H), 8.53 (d, J = 2.3, 1H),8.27 (dd, J = 9.1, 2.4, 1H), 7.06 (d, J = 4.9, 1H),6.99 (s, 1H), 6.08 (d, J = 4.9, 1H), 3.76-3.69(m, 8H), 2.30 (s, 3H), 2.21 (s, 3H)::US10172859, Example 196::US10172859, Example 203::US10172859, Example 204::US11065253, Example 204::US9732094, Example 204	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315774&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954852	383542479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659685	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2S/c1-13-14(2)32-23(28-13)21(30)18-9-15(11-25-22(18)24)20-17-4-3-16(10-19(17)26-12-27-20)29-5-7-31-8-6-29/h3-4,9-12,21,30H,5-8H2,1-2H3	JZLKXSPJLMDHOQ-UHFFFAOYSA-N	315772	(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.58-8.56 (m, 1H), 8.37 (dd, J = 9.0, 2.4,1H), 7.87 (d, J = 9.4, 1H), 7.57 (dd, J = 9.4, 2.6,1H), 7.22 (d, J = 2.5, 1H), 6.99 (d, J = 5.1, 1H),6.11 (d, J = 5.1, 1H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H), 2.30 (s, 3H), 2.19 (s, 3H)::US10172859, Example 194::US10172859, Example 205::US10172859, Example 206::US11065253, Example 206::US9732094, Example 206	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954971	383542477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659687	Cc1nc(sc1C)C(O)c1cc(cnc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H22FN5O2S/c1-13-14(2)32-23(28-13)21(30)18-9-15(11-25-22(18)24)20-17-4-3-16(10-19(17)26-12-27-20)29-5-7-31-8-6-29/h3-4,9-12,21,30H,5-8H2,1-2H3	JZLKXSPJLMDHOQ-UHFFFAOYSA-N	315772	(4,5-Dimethyl- thiazol-2-yl)-[2- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- pyridin-3-yl]- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.58-8.56 (m, 1H), 8.37 (dd, J = 9.0, 2.4,1H), 7.87 (d, J = 9.4, 1H), 7.57 (dd, J = 9.4, 2.6,1H), 7.22 (d, J = 2.5, 1H), 6.99 (d, J = 5.1, 1H),6.11 (d, J = 5.1, 1H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H), 2.30 (s, 3H), 2.19 (s, 3H)::US10172859, Example 194::US10172859, Example 205::US10172859, Example 206::US11065253, Example 206::US9732094, Example 206	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315772&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954971	383542477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659689	Cc1cc(F)c(cc1C(O)c1nccs1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-14-10-19(24)18(12-17(14)22(29)23-25-4-9-31-23)21-16-3-2-15(11-20(16)26-13-27-21)28-5-7-30-8-6-28/h2-4,9-13,22,29H,5-8H2,1H3	BIYBXRUQFCDOHJ-UHFFFAOYSA-N	315785	US10172859, Example 207::US10172859, Example 209::US10172859, Example 210::US11065253, Example 210::US9732094, Example 210::[4-Fluoro-2-methyl-5-(7-morpholinylquinazolin-4-yl)phenyl]thiazol-2-ylmethanol (EXAMPLE 207)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696365	383542486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659691	OC(c1nccs1)c1ccc(F)c(c1)-c1nc(nc2cc(ccc12)N1CCOCC1)C#C	InChI=1S/C24H19FN4O2S/c1-2-21-27-20-14-16(29-8-10-31-11-9-29)4-5-17(20)22(28-21)18-13-15(3-6-19(18)25)23(30)24-26-7-12-32-24/h1,3-7,12-14,23,30H,8-11H2	MEFSRUHZMYIWLE-UHFFFAOYSA-N	315786	US10172859, Example 208::US10172859, Example 215::US10172859, Example 216::US11065253, Example 216::US9732094, Example 216::[3-(2-Ethynyl-7-morpholinylquinazolin-4-yl)-4-fluorophenyl]thiazol-2-ylmethanol (EXAMPLE 208)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696405	383542487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659693	Cc1cc(F)c(cc1C(O)c1nccs1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-14-10-19(24)18(12-17(14)22(29)23-25-4-9-31-23)21-16-3-2-15(11-20(16)26-13-27-21)28-5-7-30-8-6-28/h2-4,9-13,22,29H,5-8H2,1H3	BIYBXRUQFCDOHJ-UHFFFAOYSA-N	315785	US10172859, Example 207::US10172859, Example 209::US10172859, Example 210::US11065253, Example 210::US9732094, Example 210::[4-Fluoro-2-methyl-5-(7-morpholinylquinazolin-4-yl)phenyl]thiazol-2-ylmethanol (EXAMPLE 207)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696365	383542486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659695	Cc1cc(F)c(cc1C(O)c1nccs1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN4O2S/c1-14-10-19(24)18(12-17(14)22(29)23-25-4-9-31-23)21-16-3-2-15(11-20(16)26-13-27-21)28-5-7-30-8-6-28/h2-4,9-13,22,29H,5-8H2,1H3	BIYBXRUQFCDOHJ-UHFFFAOYSA-N	315785	US10172859, Example 207::US10172859, Example 209::US10172859, Example 210::US11065253, Example 210::US9732094, Example 210::[4-Fluoro-2-methyl-5-(7-morpholinylquinazolin-4-yl)phenyl]thiazol-2-ylmethanol (EXAMPLE 207)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315785&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696365	383542486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659697	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H19FN4O2S/c23-18-4-1-14(21(28)22-24-5-10-30-22)11-17(18)20-16-3-2-15(12-19(16)25-13-26-20)27-6-8-29-9-7-27/h1-5,10-13,21,28H,6-9H2	XHIWYXBOVDWOHO-UHFFFAOYSA-N	315789	US10172859, Example 211::US10172859, Example 212::US10172859, Example 213::US11065253, Example 213::US9732094, Example 213::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2- ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.78-7.61 (m, 4H), 7.57-7.49 (m, 2H),7.46-7.37 (m, 1H), 7.23-7.17 (m, 1H), 6.95(s, 1H), 6.08 (s, 1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954919	383542488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659699	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H19FN4O2S/c23-18-4-1-14(21(28)22-24-5-10-30-22)11-17(18)20-16-3-2-15(12-19(16)25-13-26-20)27-6-8-29-9-7-27/h1-5,10-13,21,28H,6-9H2	XHIWYXBOVDWOHO-UHFFFAOYSA-N	315789	US10172859, Example 211::US10172859, Example 212::US10172859, Example 213::US11065253, Example 213::US9732094, Example 213::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2- ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.78-7.61 (m, 4H), 7.57-7.49 (m, 2H),7.46-7.37 (m, 1H), 7.23-7.17 (m, 1H), 6.95(s, 1H), 6.08 (s, 1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954919	383542488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659701	OC(c1nccs1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C22H19FN4O2S/c23-18-4-1-14(21(28)22-24-5-10-30-22)11-17(18)20-16-3-2-15(12-19(16)25-13-26-20)27-6-8-29-9-7-27/h1-5,10-13,21,28H,6-9H2	XHIWYXBOVDWOHO-UHFFFAOYSA-N	315789	US10172859, Example 211::US10172859, Example 212::US10172859, Example 213::US11065253, Example 213::US9732094, Example 213::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thiazol-2- ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.78-7.61 (m, 4H), 7.57-7.49 (m, 2H),7.46-7.37 (m, 1H), 7.23-7.17 (m, 1H), 6.95(s, 1H), 6.08 (s, 1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315789&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954919	383542488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659703	Cn1ccnc1C(O)c1ccc(F)c(c1)-c1nc(Cl)nc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21ClFN5O2/c1-29-7-6-26-22(29)21(31)14-2-5-18(25)17(12-14)20-16-4-3-15(30-8-10-32-11-9-30)13-19(16)27-23(24)28-20/h2-7,12-13,21,31H,8-11H2,1H3	TUVXYPBPBLPGEE-UHFFFAOYSA-N	335690	US9732094, Example 214::[3-(2-Chloro-7- morpholin-4-yl- quinazolin-4-yl)- 4-fluoro-phenyl]- (2-methyl-2H- pyrazol-3-yl)- methanol	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335690&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966383	384987849							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659705	OC(c1nccs1)c1ccc(F)c(c1)-c1nc(nc2cc(ccc12)N1CCOCC1)C#C	InChI=1S/C24H19FN4O2S/c1-2-21-27-20-14-16(29-8-10-31-11-9-29)4-5-17(20)22(28-21)18-13-15(3-6-19(18)25)23(30)24-26-7-12-32-24/h1,3-7,12-14,23,30H,8-11H2	MEFSRUHZMYIWLE-UHFFFAOYSA-N	315786	US10172859, Example 208::US10172859, Example 215::US10172859, Example 216::US11065253, Example 216::US9732094, Example 216::[3-(2-Ethynyl-7-morpholinylquinazolin-4-yl)-4-fluorophenyl]thiazol-2-ylmethanol (EXAMPLE 208)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696405	383542487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659707	OC(c1nccs1)c1ccc(F)c(c1)-c1nc(nc2cc(ccc12)N1CCOCC1)C#C	InChI=1S/C24H19FN4O2S/c1-2-21-27-20-14-16(29-8-10-31-11-9-29)4-5-17(20)22(28-21)18-13-15(3-6-19(18)25)23(30)24-26-7-12-32-24/h1,3-7,12-14,23,30H,8-11H2	MEFSRUHZMYIWLE-UHFFFAOYSA-N	315786	US10172859, Example 208::US10172859, Example 215::US10172859, Example 216::US11065253, Example 216::US9732094, Example 216::[3-(2-Ethynyl-7-morpholinylquinazolin-4-yl)-4-fluorophenyl]thiazol-2-ylmethanol (EXAMPLE 208)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315786&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696405	383542487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659709	OC(c1cccnc1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20F2N4O2/c25-20-12-21(26)19(24(31)15-2-1-5-27-13-15)11-18(20)23-17-4-3-16(10-22(17)28-14-29-23)30-6-8-32-9-7-30/h1-5,10-14,24,31H,6-9H2	YHVNTTRZSKTBOF-UHFFFAOYSA-N	315795	US10172859, Example 217::US11065253, Example 217::US9732094, Example 217::[2,4-Difluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]pyridin-3-ylmethanol 	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315795&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954959	383542490							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659711	OC(c1ccccn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20F2N4O2/c25-19-13-20(26)18(24(31)21-3-1-2-6-27-21)12-17(19)23-16-5-4-15(11-22(16)28-14-29-23)30-7-9-32-10-8-30/h1-6,11-14,24,31H,7-10H2	JMUJEVQDCVELNK-UHFFFAOYSA-N	315796	US10172859, Example 218::US11065253, Example 218::US9732094, Example 218::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridin-2-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.50-8.46 (m, 1H), 7.82 (td, J = 7.7, 1.8,1H), 7.68 (t, J = 8.1, 1H), 7.64-7.59 (m, 1H),7.57-7.50 (m, 2H), 7.43 (t, J = 10.1, 1H), 7.29-7.24 (m, 1H), 7.21-7.17 (m, 1H), 6.34 (d,J = 5.0, 1H), 6.02 (d, J = 5.0, 1H), 3.82-3.72 (m,4H), 3.48-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315796&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954763	383542491							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659713	Cn1nc(ccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-30-22(32)5-4-20(29-30)24(33)17-11-16(18(25)12-19(17)26)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,33H,6-9H2,1H3	NYVZJLKLJBXDKC-UHFFFAOYSA-N	315797	6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.85 (t, J = 8.1, 1H), 7.61-7.51 (m, 3H),7.47 (t, J = 10.1, 1H), 7.21 (d, J = 2.3, 1H), 6.94(d, J = 9.6, 1H), 6.56 (d, J = 4.8, 1H), 5.85 (d,J = 4.8, 1H), 3.81-3.75 (m, 4H), 3.60 (s, 3H),3.48-3.42 (m, 4H)::US10172859, Example 219::US11065253, Example 219::US9732094, Example 219	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315797&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954888	383542492							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659715	Cn1nc(ccc1=O)C(O)c1ccc(F)c(c1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-30-20(32)7-6-18(29-30)24(33)16-4-5-17(25)21(22(16)26)23-15-3-2-14(12-19(15)27-13-28-23)31-8-10-34-11-9-31/h2-7,12-13,24,33H,8-11H2,1H3	SGELBDISKAUAEL-UHFFFAOYSA-N	315798	6-{[2,4-Difluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.75 (d, J = 9.6, 1H), 7.67-7.61 (m, 1H),7.51 (qd, J = 9.4, 2.6, 2H), 7.32 (t, J = 8.8, 1H),7.20 (d, J = 2.3, 1H), 6.99 (d, J = 9.7, 1H), 6.64(d, J = 5.1, 1H), 6.02 (d, J = 5.1, 1H), 3.78 (t,J = 4.9, 4H), 3.57 (s, 3H), 3.45 (t, J = 4.9, 4H)::US10172859, Example 220::US11065253, Example 220::US9732094, Example 220	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315798&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954906	383542493							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659717	COc1ccc(cn1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-33-23-5-2-15(13-28-23)25(32)19-11-18(20(26)12-21(19)27)24-17-4-3-16(10-22(17)29-14-30-24)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	CCKHVCHOSUZMRH-UHFFFAOYSA-N	315799	US10172859, Example 221::US11065253, Example 221::US9732094, Example 221::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridin-3-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.17 (d, J = 2.4, 1H), 7.84 (t, J = 8.2, 1H),7.63 (dd, J = 8.6, 2.5, 1H), 7.60-7.52 (m, 2H),7.44 (t, J = 10.2, 1H), 7.21 (d, J = 2.3, 1H), 6.79(d, J = 8.6, 1H), 6.22 (d, J = 4.0, 1H), 5.99 (d,J = 3.7, 1H), 3.83 (s, 3H), 3.80-3.76 (m, 4H),3.47-3.43 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315799&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954840	383542494							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659719	OC(c1ccc2ncnn2c1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-20-11-21(27)19(25(34)15-1-4-23-29-14-31-33(23)12-15)10-18(20)24-17-3-2-16(9-22(17)28-13-30-24)32-5-7-35-8-6-32/h1-4,9-14,25,34H,5-8H2	QAEAQPVUUPLITF-UHFFFAOYSA-N	315800	US10172859, Example 222::US11065253, Example 222::US9732094, Example 222::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[1,5-a]pyridin- 6-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.98-8.95 (m, 1H), 8.49 (s, 1H), 7.88 (t,J = 8.1, 1H), 7.83-7.80 (m, 1H), 7.62-7.56 (m,2H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.48 (t, J = 10.1,1H), 7.20 (d, J = 2.4, 1H), 6.52 (s, 1H), 6.17 (s,1H), 3.82-3.74 (m, 4H), 3.49-3.41 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315800&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955014	383542495							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659721	OC(c1cn2ccnc2cn1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-11-20(27)18(25(34)22-13-33-4-3-28-23(33)12-29-22)10-17(19)24-16-2-1-15(9-21(16)30-14-31-24)32-5-7-35-8-6-32/h1-4,9-14,25,34H,5-8H2	FRGZDZJCSYUKHF-UHFFFAOYSA-N	315801	US10172859, Example 223::US11065253, Example 223::US9732094, Example 223::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-6-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s,1H), 9.06-9.02 (m, 1H), 8.83 (t, J = 1.3, 1H),8.25-8.22 (m, 1H), 7.86 (d, J = 1.0, 1H), 7.76 (t,J = 8.1, 1H), 7.63-7.56 (m, 2H), 7.52 (t, J = 10.1,1H), 7.24 (d, J = 2.1, 1H), 6.53 (d, J = 4.7, 1H),6.16 (d, J = 4.5, 1H), 3.87-3.80 (m, 4H), 3.54-3.46 (m, 4H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315801&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954896	383542496							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659723	COc1ccc(nc1)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-33-16-3-5-22(28-13-16)25(32)19-11-18(20(26)12-21(19)27)24-17-4-2-15(10-23(17)29-14-30-24)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	QEZRHTYDAFPTCM-UHFFFAOYSA-N	315802	US10172859, Example 224::US11065253, Example 224::US9732094, Example 224::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyridin-2-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.20-8.17 (m, 1H), 7.68 (t, J = 8.1, 1H),7.55-7.51 (m, 3H), 7.43-7.37 (m, 2H), 7.21-7.18 (m, 1H), 6.23 (d, J = 4.9, 1H), 5.98 (d,J = 4.6, 1H), 3.80 (s, 3H), 3.80-3.74 (m, 4H),	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315802&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954775	383542497							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659725	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 129::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::US10172859, Example 244::US10172859, Example 262::US11065253, Example 262::US9732094, Example 262::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	1IX	7Z88,7Z87,7OTY	117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659727	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 226::US10172859, Example 238::US10172859, Example 243::US10172859, Example 259::US10172859, Example 78::US11065253, Example 259::US9732094, Example 259::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659729	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-20-3-2-18(29-30-20)23(32)14-9-15(17(25)10-16(14)24)21-22-19(27-12-28-21)8-13(11-26-22)31-4-6-34-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	NGZQOMGGFCGYBY-UHFFFAOYSA-N	315805	US10172859, Example 227::US10172859, Example 228::US10172859, Example 257::US11065253, Example 257::US9732094, Example 257::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966394	383542498							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659731	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-20-3-2-18(29-30-20)23(32)14-9-15(17(25)10-16(14)24)21-22-19(27-12-28-21)8-13(11-26-22)31-4-6-34-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	NGZQOMGGFCGYBY-UHFFFAOYSA-N	315805	US10172859, Example 227::US10172859, Example 228::US10172859, Example 257::US11065253, Example 257::US9732094, Example 257::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966394	383542498							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659733	CNC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC	InChI=1S/C26H24ClFN6O3/c1-29-25(35)22(24-26(36-2)31-6-5-30-24)17-12-18(20(28)13-19(17)27)23-16-4-3-15(11-21(16)32-14-33-23)34-7-9-37-10-8-34/h3-6,11-14,22H,7-10H2,1-2H3,(H,29,35)	NOVGLOQBGGWKSC-UHFFFAOYSA-N	315807	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxypyrazin-2- yl)-N-methyl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.26 (q, J = 4.5, 1H), 8.13 (d, J = 2.8, 1H), 8.11(d, J = 2.8, 1H), 7.73 (d, J = 9.6, 1H), 7.59 (dd,J = 9.4, 2.6, 1H), 7.56 (dd, J = 9.5, 2.3, 1H), 7.47 (d,J = 7.7, 1H), 7.20 (d, J = 2.2, 1H), 5.66 (s, 1H), 3.94(s, 3H), 3.80-3.71 (m, 4H), 3.48-3.42 (m, 4H),2.61 (d, J = 4.6, 3H).::US10172859, Example 229::US11065253, Example 229::US9732094, Example 229	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954808	383542499							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659735	CNC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C26H23ClFN5O2/c1-29-26(34)23(25-20(27)3-2-8-30-25)16-4-7-21(28)19(13-16)24-18-6-5-17(14-22(18)31-15-32-24)33-9-11-35-12-10-33/h2-8,13-15,23H,9-12H2,1H3,(H,29,34)	UUVNBMVWHDQRNZ-UHFFFAOYSA-N	315808	2-(3-Chloro-pyridin- 2-yl)-2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-N-methyl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.51 (dd, J = 4.7, 1.4, 1H), 8.03 (q, J = 4.4, 1H),7.92 (dd, J = 8.1, 1.5, 1H), 7.63 (dd, J = 9.4, 2.7, 1H),7.58-7.54 (m, 3H), 7.41-7.33 (m, 2H), 7.20 (d,J = 2.4, 1H), 5.52 (s, 1H), 3.85-3.71 (m, 4H), 3.51-3.40 (m, 4H), 2.60 (d, J = 4.6, 3H).::US10172859, Example 230::US9732094, Example 230	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315808&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711721	383542500							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659737	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-23-21(26-2-3-27-23)22(32)14-9-15(17(25)10-16(14)24)19-20-18(29-12-30-19)8-13(11-28-20)31-4-6-34-7-5-31/h2-3,8-12,22,32H,4-7H2,1H3	RRCYTFPMQJMLJV-UHFFFAOYSA-N	315809	US10172859, Example 231::US10172859, Example 232::US10172859, Example 247::US11065253, Example 247::US9732094, Example 247::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966396	383542501							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659739	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-23-21(26-2-3-27-23)22(32)14-9-15(17(25)10-16(14)24)19-20-18(29-12-30-19)8-13(11-28-20)31-4-6-34-7-5-31/h2-3,8-12,22,32H,4-7H2,1H3	RRCYTFPMQJMLJV-UHFFFAOYSA-N	315809	US10172859, Example 231::US10172859, Example 232::US10172859, Example 247::US11065253, Example 247::US9732094, Example 247::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966396	383542501							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659741	Cc1nccnc1[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H21FN6O2/c1-14-20(26-5-4-25-14)23(31)15-2-3-18(24)17(10-15)21-22-19(28-13-29-21)11-16(12-27-22)30-6-8-32-9-7-30/h2-5,10-13,23,31H,6-9H2,1H3/t23-/m0/s1	JJEXYMGNEIIEPL-QHCPKHFHSA-N	315811	(S)-[4-Fluoro-3-(7- morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 233::US11065253, Example 233::US9732094, Example 233	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315811&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954898	383542502							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659743	Cc1nccnc1[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H21FN6O2/c1-14-20(26-5-4-25-14)23(31)15-2-3-18(24)17(10-15)21-22-19(28-13-29-21)11-16(12-27-22)30-6-8-32-9-7-30/h2-5,10-13,23,31H,6-9H2,1H3/t23-/m1/s1	JJEXYMGNEIIEPL-HSZRJFAPSA-N	315812	(R)-[4-Fluoro-3-(7- morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 234::US11065253, Example 234::US9732094, Example 234	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315812&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696208	383542503							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659745	Fc1cc(Cl)c(Cc2ccc3nccn3n2)cc1-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20ClFN6O/c26-21-14-22(27)20(12-16(21)11-17-1-4-24-28-5-6-33(24)31-17)25-19-3-2-18(13-23(19)29-15-30-25)32-7-9-34-10-8-32/h1-6,12-15H,7-11H2	INTDVNQLZOTAHT-UHFFFAOYSA-N	315813	4-(4-Chloro-2-fluoro- 5-imidazo[1,2-b]- pyridazin-6-ylmethyl- phenyl)-7-morpholin- 4-ylquinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.22 (s, 1H), 8.07 (d, J = 9.4, 1H), 7.78-7.74(m, 2H), 7.74-7.71 (m, 1H), 7.60 (dd, J = 9.4, 3.1,1H), 7.54 (dd, J = 9.4, 2.5, 1H), 7.20 (d, J = 2.5, 1H),7.16 (d, J = 9.4, 1H), 4.42 (s, 2H), 3.80-3.75 (m,4H), 3.47-3.43 (m, 4H).::US10172859, Example 235::US11065253, Example 235::US9732094, Example 235	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315813&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696240	383542504							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659747	CNC(=O)C(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H23ClFN7O2/c1-30-27(37)25(22-4-5-24-31-6-7-36(24)34-22)18-13-19(21(29)14-20(18)28)26-17-3-2-16(12-23(17)32-15-33-26)35-8-10-38-11-9-35/h2-7,12-15,25H,8-11H2,1H3,(H,30,37)	XLTXMRIUYGBHCH-UHFFFAOYSA-N	315814	2-[2-Chloro-4-fluoro- 4-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-imidazo- [1,2-b]pyridazin-6-yl- N-methylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.56 (q, J = 4.5, 1H), 8.26 (s, 1H), 8.10 (d,J = 9.5, 1H), 7.81 (d, J = 9.5, 1H), 7.77 (d, J = 1.2,1H), 7.74 (d, J = 7.6, 1H), 7.60 (dd, J = 9.4, 3.0, 1H),7.55 (dd, J = 9.4, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 7.12(d, J = 9.5, 1H), 5.62 (s, 1H), 3.81-3.75 (m, 4H),3.48-3.40 (m, 4H), 2.65 (d, J = 4.6, 3H).::US10172859, Example 236::US11065253, Example 236::US9732094, Example 236	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315814&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954752	383542505							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659749	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H21FN6O2/c1-14-20(26-5-4-25-14)23(31)15-2-3-18(24)17(10-15)21-22-19(28-13-29-21)11-16(12-27-22)30-6-8-32-9-7-30/h2-5,10-13,23,31H,6-9H2,1H3	JJEXYMGNEIIEPL-UHFFFAOYSA-N	315815	US10172859, Example 237::US11065253, Example 237::US9732094, Example 237::[4-Fluoro-3-(7-morpholin-4-ylpyrido[3,2-d}pyrimidin-4-yl)phenyl]-(3-methylpyrazin-2-yl)-methanol 	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315815&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696211	383542506							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659751	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 226::US10172859, Example 238::US10172859, Example 243::US10172859, Example 259::US10172859, Example 78::US11065253, Example 259::US9732094, Example 259::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659753	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 129::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::US10172859, Example 244::US10172859, Example 262::US11065253, Example 262::US9732094, Example 262::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	1IX	7Z88,7Z87,7OTY	117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659755	Cc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O2/c1-13-20(27-3-2-26-13)23(32)15-9-16(18(25)10-17(15)24)21-22-19(29-12-30-21)8-14(11-28-22)31-4-6-33-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	BAUZLLBZQGLKDX-UHFFFAOYSA-N	315819	US10172859, Example 240::US11065253, Example 240::US9732094, Example 240::[2-Chloro-4-fluoro-5- (7-morphlin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.23 (s,1H), 9.06 (d, J = 2.9, 1H), 8.43 (d, J = 2.5, 1H), 8.33(d, J = 2.5, 1H), 8.05 (d, J = 7.5, 1H), 7.54 (d, J = 9.2,1H), 7.48 (d, J = 2.9, 1H), 6.65-6.27 (m, 1H), 6.25-6.22 (m, 1H), 3.82-3.77 (m, 4H), 3.58-3.52 (m,4H), 2.74 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315819&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966397	383542508							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659757	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 241::US10172859, Example 242::US10172859, Example 258::US10172859, Example 468::US11065253, Example 258::US9732094, Example 258::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659759	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 241::US10172859, Example 242::US10172859, Example 258::US10172859, Example 468::US11065253, Example 258::US9732094, Example 258::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659761	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 226::US10172859, Example 238::US10172859, Example 243::US10172859, Example 259::US10172859, Example 78::US11065253, Example 259::US9732094, Example 259::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659763	COc1ccc(cc1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN3O3/c1-33-18-5-2-16(3-6-18)26(32)20-13-21(23(28)14-22(20)27)25-19-7-4-17(12-24(19)29-15-30-25)31-8-10-34-11-9-31/h2-7,12-15,26,32H,8-11H2,1H3	AOEZOUPTUFFZPT-UHFFFAOYSA-N	335721	US9732094, Example 244::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(6- methoxypyridazin-3- yl)methanol (Ena 1)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335721&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138752682	384987879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659765	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H20FN5O2S/c1-13-19(25-5-4-24-13)21(29)14-2-3-16(23)15(10-14)20-22-17(26-12-27-20)11-18(31-22)28-6-8-30-9-7-28/h2-5,10-12,21,29H,6-9H2,1H3	JVZGLRHIUDPKQN-UHFFFAOYSA-N	315824	US10172859, Example 245::US10172859, Example 246::US10172859, Example 265::US11065253, Example 265::US9732094, Example 265::[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696361	383542510							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659767	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H20FN5O2S/c1-13-19(25-5-4-24-13)21(29)14-2-3-16(23)15(10-14)20-22-17(26-12-27-20)11-18(31-22)28-6-8-30-9-7-28/h2-5,10-12,21,29H,6-9H2,1H3	JVZGLRHIUDPKQN-UHFFFAOYSA-N	315824	US10172859, Example 245::US10172859, Example 246::US10172859, Example 265::US11065253, Example 265::US9732094, Example 265::[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696361	383542510							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659769	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-23-21(26-2-3-27-23)22(32)14-9-15(17(25)10-16(14)24)19-20-18(29-12-30-19)8-13(11-28-20)31-4-6-34-7-5-31/h2-3,8-12,22,32H,4-7H2,1H3	RRCYTFPMQJMLJV-UHFFFAOYSA-N	315809	US10172859, Example 231::US10172859, Example 232::US10172859, Example 247::US11065253, Example 247::US9732094, Example 247::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966396	383542501							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659771	Cc1nccnc1[C@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)17(10-15)23-21-19(26)11-16(12-20(21)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m1/s1	GCFJFHHQAJXDCA-XMMPIXPASA-N	315827	(R)-[4-Fluoro-3-(5- fluoro-7-morpholin-4- ylquinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 248::US11065253, Example 248::US9732094, Example 248	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315827&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696390	383542511							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659773	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-24-22(28-2-3-29-24)23(33)14-10-15(17(26)11-16(14)25)21-20-18(27)8-13(9-19(20)30-12-31-21)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	OWOGJPGABWHWIU-UHFFFAOYSA-N	315828	US10172859, Example 249::US10172859, Example 250::US10172859, Example 266::US11065253, Example 266::US9732094, Example 266::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696440	383542512							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659775	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-24-22(28-2-3-29-24)23(33)14-10-15(17(26)11-16(14)25)21-20-18(27)8-13(9-19(20)30-12-31-21)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	OWOGJPGABWHWIU-UHFFFAOYSA-N	315828	US10172859, Example 249::US10172859, Example 250::US10172859, Example 266::US11065253, Example 266::US9732094, Example 266::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696440	383542512							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659777	Cc1nccnc1[C@@H](O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)17(10-15)23-21-19(26)11-16(12-20(21)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m0/s1	GCFJFHHQAJXDCA-DEOSSOPVSA-N	315830	(S)-[4-fluoro-3-(5- fluoro-7-morpholin-4- ylquinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 251::US11065253, Example 251::US9732094, Example 251	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315830&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711725	383542513							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659779	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)14-2-3-17(25)16(10-14)21-20-18(26)11-15(12-19(20)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MBESFUDQRFVLFJ-UHFFFAOYSA-N	315831	US10172859, Example 252::US10172859, Example 253::US10172859, Example 267::US11065253, Example 267::US9732094, Example 267::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696418	383542514							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659781	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)14-2-3-17(25)16(10-14)21-20-18(26)11-15(12-19(20)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MBESFUDQRFVLFJ-UHFFFAOYSA-N	315831	US10172859, Example 252::US10172859, Example 253::US10172859, Example 267::US11065253, Example 267::US9732094, Example 267::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696418	383542514							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659783	CNC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C	InChI=1S/C26H24ClFN6O2/c1-15-24(31-6-5-30-15)23(26(35)29-2)18-12-19(21(28)13-20(18)27)25-17-4-3-16(11-22(17)32-14-33-25)34-7-9-36-10-8-34/h3-6,11-14,23H,7-10H2,1-2H3,(H,29,35)	ODLHJEBFKWXYOW-UHFFFAOYSA-N	315833	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-N-methyl-2- (3-methyl-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.41 (d, J = 2.6, 1H), 8.39 (d, J = 2.5, 1H), 8.30(q, J = 4.5, 1H), 7.74 (d, J = 9.5, 1H), 7.59 (dd,J = 9.4, 2.6, 1H), 7.55 (dd, J = 9.5, 2.4, 1H), 7.47 (d,J = 7.7, 1H), 7.20 (d, J = 2.3, 1H), 5.66 (s, 1H), 3.78(t, J = 5.8, 3.9, 4H), 3.46 (t, J = 4.9, 4H), 2.63 (d,J = 4.5, 3H), 2.52 (s, 3H).::US10172859, Example 254::US11065253, Example 254::US9732094, Example 254	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315833&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954895	383542515							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659785	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-5-4-19(29-30-21)24(32)14-2-3-17(25)16(10-14)23-22-18(26)11-15(12-20(22)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	OWXPXVCRAHRBLK-UHFFFAOYSA-N	315834	US10172859, Example 255::US10172859, Example 256::US10172859, Example 260::US11065253, Example 260::US9732094, Example 260::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696697	383542516							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659787	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-5-4-19(29-30-21)24(32)14-2-3-17(25)16(10-14)23-22-18(26)11-15(12-20(22)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	OWXPXVCRAHRBLK-UHFFFAOYSA-N	315834	US10172859, Example 255::US10172859, Example 256::US10172859, Example 260::US11065253, Example 260::US9732094, Example 260::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696697	383542516							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659789	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cnc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3/c1-33-20-3-2-18(29-30-20)23(32)14-9-15(17(25)10-16(14)24)21-22-19(27-12-28-21)8-13(11-26-22)31-4-6-34-7-5-31/h2-3,8-12,23,32H,4-7H2,1H3	NGZQOMGGFCGYBY-UHFFFAOYSA-N	315805	US10172859, Example 227::US10172859, Example 228::US10172859, Example 257::US11065253, Example 257::US9732094, Example 257::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- pyrido[3,2-d}- pyrimidin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966394	383542498							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659791	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 241::US10172859, Example 242::US10172859, Example 258::US10172859, Example 468::US11065253, Example 258::US9732094, Example 258::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659793	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)16-2-5-20(25)19(12-16)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	PCPCDRDQIBENHU-UHFFFAOYSA-N	315653	US10172859, Example 226::US10172859, Example 238::US10172859, Example 243::US10172859, Example 259::US10172859, Example 78::US11065253, Example 259::US9732094, Example 259::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (3-methylpyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.43 (s, 2H), 7.63-7.55 (m, 2H), 7.55-7.50 (m, 2H), 7.42-7.34 (m, 1H), 7.22-7.17 (m, 1H), 6.28 (d, J = 5.5, 1H), 6.08 (d, J = 5.4, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H), 2.58-2.53 (m, 3H)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315653&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292268	383542392							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659795	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-5-4-19(29-30-21)24(32)14-2-3-17(25)16(10-14)23-22-18(26)11-15(12-20(22)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	OWXPXVCRAHRBLK-UHFFFAOYSA-N	315834	US10172859, Example 255::US10172859, Example 256::US10172859, Example 260::US11065253, Example 260::US9732094, Example 260::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696697	383542516							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659797	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C25H21ClF2N6O3/c1-36-25-23(30-2-3-31-25)20(24(29)35)14-10-15(17(27)11-16(14)26)22-21-18(28)8-13(9-19(21)32-12-33-22)34-4-6-37-7-5-34/h2-3,8-12,20H,4-7H2,1H3,(H2,29,35)	ASBYXEDKVZWWLT-UHFFFAOYSA-N	315840	2-[2-Chloro-4-fluoro- 5-(5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (400 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.10 (d, J = 2.8, 1H), 8.07 (d, J = 2.8, 1H), 7.56(d, J = 7.7, 1H), 7.51 (d, J = 9.7, 1H), 7.41-6.85 (m,5H), 3.96 (s, 3H), 3.82-3.74 (m, 4H), 3.52-3.45(m, 4H).::US10172859, Example 261::US11065253, Example 261::US9732094, Example 261	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315840&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954964	383542517							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659799	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	MOWXJLUYGFNTAL-UHFFFAOYSA-N	315705	US10172859, Example 129::US10172859, Example 137::US10172859, Example 225::US10172859, Example 239::US10172859, Example 244::US10172859, Example 262::US11065253, Example 262::US9732094, Example 262::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6- methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	1IX	7Z88,7Z87,7OTY	117696445	383542436							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659801	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-21-3-2-19(30-31-21)24(33)14-10-15(17(26)11-16(14)25)23-22-18(27)8-13(9-20(22)28-12-29-23)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	IPOFTWPZUKXNTC-UHFFFAOYSA-N	315842	US10172859, Example 263::US10172859, Example 271::US10172859, Example 278::US11065253, Example 278::US9732094, Example 278::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazoin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696333	383542518							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659803	Cc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H19ClFN5O2S/c1-12-19(26-3-2-25-12)21(30)13-8-14(16(24)9-15(13)23)20-22-17(27-11-28-20)10-18(32-22)29-4-6-31-7-5-29/h2-3,8-11,21,30H,4-7H2,1H3	IZJZSFQNGRBZAU-UHFFFAOYSA-N	315843	US10172859, Example 264::US11065253, Example 264::US9732094, Example 264::[2-Chloro-4-fluoro-5- (6-morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 8.93 (s,1H), 8.43 (d, J = 2.5, 1H), 8.33 (d, J = 2.4, 1H), 8.11(d, J = 7.9, 1H), 7.63 (d, J = 9.9, 1H), 6.56 (s, 1H),6.47 (d, J = 6.0, 1H), 6.23 (d, J = 4.6 1H), 3.79-3.71 (m, 4H), 3.48-3.39 (m, 4H), 2.73 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315843&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696430	383542519							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659805	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C22H20FN5O2S/c1-13-19(25-5-4-24-13)21(29)14-2-3-16(23)15(10-14)20-22-17(26-12-27-20)11-18(31-22)28-6-8-30-9-7-28/h2-5,10-12,21,29H,6-9H2,1H3	JVZGLRHIUDPKQN-UHFFFAOYSA-N	315824	US10172859, Example 245::US10172859, Example 246::US10172859, Example 265::US11065253, Example 265::US9732094, Example 265::[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696361	383542510							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659807	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-24-22(28-2-3-29-24)23(33)14-10-15(17(26)11-16(14)25)21-20-18(27)8-13(9-19(20)30-12-31-21)32-4-6-35-7-5-32/h2-3,8-12,23,33H,4-7H2,1H3	OWOGJPGABWHWIU-UHFFFAOYSA-N	315828	US10172859, Example 249::US10172859, Example 250::US10172859, Example 266::US11065253, Example 266::US9732094, Example 266::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696440	383542512							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659809	COc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)14-2-3-17(25)16(10-14)21-20-18(26)11-15(12-19(20)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	MBESFUDQRFVLFJ-UHFFFAOYSA-N	315831	US10172859, Example 252::US10172859, Example 253::US10172859, Example 267::US11065253, Example 267::US9732094, Example 267::[4-Fluoro-3-(5-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696418	383542514							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659811	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)17(10-15)23-21-19(26)11-16(12-20(21)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	GCFJFHHQAJXDCA-UHFFFAOYSA-N	315848	US10172859, Example 268::US11065253, Example 268::US9732094, Example 268::[4-Fluoro-3-(5-fluoro-7-morpholin-4-ylquinazolin-4-yl)phenyl]-(3-methylpyrazin-2-yl)methanol (268), [2-chloro-4-fluoro-5-(5-fluoro-7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol (278)	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315848&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696300	383542521							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659813	Cc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C23H20ClFN6O2S/c1-12-20(28-3-2-27-12)19(23(26)32)13-8-14(16(25)9-15(13)24)21-22-17(29-11-30-21)10-18(34-22)31-4-6-33-7-5-31/h2-3,8-11,19H,4-7H2,1H3,(H2,26,32)	YOTHGDNLEVBATQ-UHFFFAOYSA-N	315849	2-[2-Chloro-4-fluoro- 5-(6-morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 8.87 (s,1H), 8.43 (d, J = 2.6, 1H), 8.40 (d, J = 2.7 1H), 7.82-7.78 (m, 1H), 7.74 (d, J = 10.0, 1H), 7.55 (d,J = 1.78), 7.41-7.36 (m, 1H), 6.53 (s, 1H), 5.63(s, 1H), 3.79-3.73 (m, 3H), 3.43-3.38 (m, 4H),2.51 (s, 3H).::US10172859, Example 269::US11065253, Example 269::US9732094, Example 269	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315849&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954872	383542522							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659815	Cc1nccnc1C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C23H21FN6O2S/c1-13-20(27-5-4-26-13)19(23(25)31)14-2-3-16(24)15(10-14)21-22-17(28-12-29-21)11-18(33-22)30-6-8-32-9-7-30/h2-5,10-12,19H,6-9H2,1H3,(H2,25,31)	HFLHZJWDDGOHGW-UHFFFAOYSA-N	315850	2-[4-Fluoro-3-(6- morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-6) ppm = 8.88 (s,1H), 8.42-8.37 (m, 2H), 7.67 (dd, J = 7.1, 2.3, 1H),7.61-7.55 (m, 2H), 7.41-7.34 (m, 1H), 7.25-7.19 (m, 1H), 6.53 (s, 1H), 5.40 (s, 1H), 3.79-3.71 (m, 4H), 3.44-3.39 (m, 4H), 2.53 (s, 3H).::US10172859, Example 270::US11065253, Example 270::US9732094, Example 270	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315850&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954819	383542523							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659817	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-21-3-2-19(30-31-21)24(33)14-10-15(17(26)11-16(14)25)23-22-18(27)8-13(9-20(22)28-12-29-23)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	IPOFTWPZUKXNTC-UHFFFAOYSA-N	315842	US10172859, Example 263::US10172859, Example 271::US10172859, Example 278::US11065253, Example 278::US9732094, Example 278::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazoin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696333	383542518							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659819	COc1ccc(nn1)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(sc12)N1CCOCC1	InChI=1S/C23H20ClFN6O3S/c1-33-18-3-2-16(29-30-18)20(23(26)32)12-8-13(15(25)9-14(12)24)21-22-17(27-11-28-21)10-19(35-22)31-4-6-34-7-5-31/h2-3,8-11,20H,4-7H2,1H3,(H2,26,32)	PCGFSZDYWRXXKO-UHFFFAOYSA-N	315852	2-[2-Chloro-4-fluoro- 5-(6-morpholin-4-yl- thieno[3,2-d}- pyrimidin-4-yl)- phenyl]-2-(6- methoxy-pyridazin-3- yl)acetamide1H NMR (400 MHz, DMSO-d6) ppm = 8.89 (s,1H), 7.94 (s, 1H), 7.81 (d, J = 7.7, 1H), 7.74 (d,J = 10.0, 1H), 7.47 (d, J = 9.2, 1H), 7.40 (s, 1H),7.19 (d, J = 9.2, 1H), 6.53 (s, 1H), 5.65 (s, 1H),4.00 (s, 3H), 3.79-3.71 (m, 4H), 3.45-3.39 (m,4H).::US10172859, Example 272::US11065253, Example 272::US9732094, Example 272	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315852&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954930	383542524							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659821	COc1ccc(nn1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(cc(F)c12)N1CCOCC1	InChI=1S/C24H20ClF2N5O3/c1-34-21-3-2-19(30-31-21)24(33)14-10-15(17(26)11-16(14)25)23-22-18(27)8-13(9-20(22)28-12-29-23)32-4-6-35-7-5-32/h2-3,8-12,24,33H,4-7H2,1H3	IPOFTWPZUKXNTC-UHFFFAOYSA-N	315842	US10172859, Example 263::US10172859, Example 271::US10172859, Example 278::US11065253, Example 278::US9732094, Example 278::[2-Chloro-4-fluoro-5- (5-fluoro-7- morpholin-4-yl- quinazoin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696333	383542518							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659823	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ncnc12	InChI=1S/C24H20FN7O2/c25-19-4-1-15(23(33)22-24-29-14-30-32(24)6-5-26-22)11-18(19)21-17-3-2-16(12-20(17)27-13-28-21)31-7-9-34-10-8-31/h1-6,11-14,23,33H,7-10H2	FVRXBVVATCNFQH-UHFFFAOYSA-N	315854	US10172859, Example 279::US11065253, Example 279::US9732094, Example 279::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[1,5-a]- pyrazin-8-ylmethanol1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 9.03 (d, J = 4.5, 1H), 8.76 (s, 1H), 8.25 (d,J = 4.5, 1H), 7.84-7.76 (m, 2H), 7.59-7.51 (m,2H), 7.39 (dd, J = 9.9, 8.5, 1H), 7.20 (d, J = 2.1, 1H),6.48 (s, 1H), 3.82-3.75 (m, 4H), 3.51-3.43 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315854	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315854&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954778	383542525							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659825	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ncnc12	InChI=1S/C25H21FN8O2/c26-19-4-1-15(21(24(27)35)23-25-31-14-32-34(25)6-5-28-23)11-18(19)22-17-3-2-16(12-20(17)29-13-30-22)33-7-9-36-10-8-33/h1-6,11-14,21H,7-10H2,(H2,27,35)	ZWRJZLXHRXIIDS-UHFFFAOYSA-N	315855	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[1,2,4]- triazolo[1,5-a]- pyrazin-8-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 9.02 (d, J = 4.5, 1H), 8.74 (s, 1H), 8.21 (d,J = 4.5, 1H), 7.79-7.75 (m, 1H), 7.74-7.69 (m,2H), 7.64 (dd, J = 9.4, 2.9, 1H), 7.56 (dd, J = 9.5,2.5, 1H), 7.45-7.40 (m, 1H), 7.31-7.27 (m, 1H),7.20 (d, J = 2.4, 1H), 5.89 (s, 1H), 3.81-3.74 (m,4H), 3.49-3.41 (m, 4H).::US10172859, Example 280::US11065253, Example 280::US9732094, Example 280	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315855&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711775	383542526							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659827	COc1ccc(nn1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(N3CCOCC3)c(F)cc12	InChI=1S/C24H21F2N5O3/c1-33-22-5-4-19(29-30-22)24(32)14-2-3-17(25)15(10-14)23-16-11-18(26)21(12-20(16)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	DSOJNLMCRNUJKA-UHFFFAOYSA-N	315856	US10172859, Example 282::US11065253, Example 282::US9732094, Example 282::[4-Fluoro-3-(6-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.24 (s,1H), 7.74-7.63 (m, 3H), 7.48-7.39 (m, 2H),7.34 (dd, J = 13.6, 3.1, 1H), 7.21 (d, J = 9.2, 1H),6.53 (d, J = 4.3, 1H), 6.03 (d, J = 4.4, 1H), 4.00 (s,3H), 3.83-3.77 (m, 4H), 3.36-3.27 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315856	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315856&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954768	383542527							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659829	Cc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(N3CCOCC3)c(F)cc12	InChI=1S/C24H21F2N5O2/c1-14-22(28-5-4-27-14)24(32)15-2-3-18(25)16(10-15)23-17-11-19(26)21(12-20(17)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	RSNFZZXIZHWRLL-UHFFFAOYSA-N	315857	US10172859, Example 283::US11065253, Example 283::US9732094, Example 283::[4-Fluoro-3-(6-fluoro- 7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.23 (s,1H), 8.46-8.41 (m, 2H), 7.66-7.58 (m, 2H),7.49-7.31 (m, 3H), 6.32 (d, J = 5.5, 1H), 6.10 (d,J = 5.5, 1H), 3.84-3.78 (m, 4H), 3.36-3.27 (m,4H), 2.57 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315857	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315857&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954979	383542528							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659831	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccsc12	InChI=1S/C26H21FN6O2S/c27-20-4-1-15(22(26(28)34)24-25-16(5-10-36-25)13-31-32-24)11-19(20)23-18-3-2-17(12-21(18)29-14-30-23)33-6-8-35-9-7-33/h1-5,10-14,22H,6-9H2,(H2,28,34)	HBIASEVIOCHSGV-UHFFFAOYSA-N	315858	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-thieno- [2,3-d}pyridazin-7-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.59 (s,1H), 9.09 (s, 1H), 8.24 (d, J = 5.3, 1H), 7.92 (s,1H), 7.73-7.65 (m, 3H), 7.57 (dd, J = 9.4, 3.1, 1H),7.50 (dd, J = 9.5, 2.5, 1H), 7.47-7.36 (m, 2H),7.19 (d, J = 2.5, 1H), 5.72 (s, 1H), 3.84-3.73 (m,4H), 3.46-3.41 (m, 4H), 9.09-9.09 (m, 0H).::US10172859, Example 284::US9732094, Example 284	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315858&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711746	383542529							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659833	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12	InChI=1S/C26H21FN6O2S/c27-20-4-1-15(23(26(28)34)25-18-5-10-36-22(18)13-31-32-25)11-19(20)24-17-3-2-16(12-21(17)29-14-30-24)33-6-8-35-9-7-33/h1-5,10-14,23H,6-9H2,(H2,28,34)	DQNFYRIXINNVDA-UHFFFAOYSA-N	315859	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-thieno- [2,3-d}pyridazin-4-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.83-9.79(m, 1H), 9.08 (s, 1H), 8.30 (d, J = 5.4, 1H), 7.81-7.75 (m, 2H), 7.75-7.68 (m, 2H), 7.56 (dd, J = 9.4,3.1, 1H), 7.49 (dd, J = 9.4, 2.6, 1H), 7.40 (dd,J = 9.8, 8.4, 1H), 7.32 (s, 1H), 7.19 (d, J = 2.5, 1H),5.90 (s, 1H), 3.81-3.74 (m, 4H), 3.47-3.40 (m,4H).::US10172859, Example 285::US11065253, Example 285::US9732094, Example 285	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315859&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711776	383542530							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659835	COc1nnc(Cl)cc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-18(12-21(25)29-30-24)23(32)14-2-5-19(26)17(10-14)22-16-4-3-15(11-20(16)27-13-28-22)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	PBEWANFAIGVJRA-UHFFFAOYSA-N	315582	(6-Chloro-5-methoxy- pyridazin-3-yl)-[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.88 (d, J = 1.0, 1H), 7.63-7.58 (m, 2H), 7.55- 7.47 (m, 2H), 7.42-7.35 (m, 1H), 7.20 (d, J = 2.3, 1H), 6.46 (d, J = 4.3, 1H), 5.85-5.82 (m, 1H), 4.00 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H)::US10172859, Example 286::US10172859, Example 9::US11065253, Example 286::US9732094, Example 286	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315582&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954747	383542341							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659837	CN1N=C(CCC1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H23ClFN5O3/c1-30-22(32)5-4-20(29-30)24(33)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-3,10-13,24,33H,4-9H2,1H3	FCQKVWFWTHCJBD-UHFFFAOYSA-N	315861	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-4,5- dihydro-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 7.84 (d, J = 7.8, 1H), 7.68 (d, J = 9.5, 1H), 7.57(dd, J = 9.4, 2.8, 1H), 7.54 (dd, J = 9.5, 2.4, 1H),7.21 (d, J = 2.3, 1H), 6.42 (s, 1H), 5.57 (s, 1H),3.81-3.75 (m, 4H), 3.47-3.43 (m, 4H), 3.16 (s,3H), 2.61-2.51 (m, 1H), 2.43-2.28 (m, 3H).::US10172859, Example 288::US11065253, Example 288::US9732094, Example 288	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315861&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954804	383542531							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659839	NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C25H20Cl2FN5O2/c26-18-2-1-5-30-24(18)22(25(29)34)16-11-17(20(28)12-19(16)27)23-15-4-3-14(10-21(15)31-13-32-23)33-6-8-35-9-7-33/h1-5,10-13,22H,6-9H2,(H2,29,34)	YFWBSWOQIFUXES-UHFFFAOYSA-N	315862	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-chloro- pyridin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.44 (dd, J = 4.7, 1.5, 1H), 7.95 (dd, J = 8.1,1.5, 1H), 7.76 (s, 1H), 7.72 (d, J = 9.6, 1H), 7.58(dd, J = 9.4, 2.9, 1H), 7.54 (dd, J = 9.5, 2.5, 1H),7.41 (d, J = 7.6, 1H), 7.35 (dd, J = 8.1, 4.7, 1H), 7.28(s, 1H), 7.19 (d, J = 2.4, 1H), 5.81 (s, 1H), 3.80-3.75 (m, 4H), 3.48-3.42 (m, 4H).::US10172859, Example 289::US11065253, Example 289::US9732094, Example 289	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315862&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954995	383542532							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659841	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nnc(Cl)c2ccsc12	InChI=1S/C26H20ClFN6O2S/c27-25-17-5-10-37-24(17)23(32-33-25)21(26(29)35)14-1-4-19(28)18(11-14)22-16-3-2-15(12-20(16)30-13-31-22)34-6-8-36-9-7-34/h1-5,10-13,21H,6-9H2,(H2,29,35)	YFPXALXVUKNUIN-UHFFFAOYSA-N	315863	2-(4-Chlorothieno- [2,3-d}pyridazin-7-yl)- 2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.41 (d, J = 5.4, 1H), 7.94 (s, 1H), 7.71-7.65(m, 3H), 7.56 (dd, J = 9.4, 3.1, 1H), 7.51 (dd,J = 9.4, 2.5, 1H), 7.48-7.40 (m, 2H), 7.20 (d,J = 2.4, 1H), 5.75 (s, 1H), 3.82-3.73 (m, 4H), 3.48-3.40 (m, 4H).::US10172859, Example 290::US11065253, Example 290::US9732094, Example 290	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315863&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954780	383542533							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659843	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nnc(Cl)c2sccc12	InChI=1S/C26H20ClFN6O2S/c27-25-24-17(5-10-37-24)23(32-33-25)21(26(29)35)14-1-4-19(28)18(11-14)22-16-3-2-15(12-20(16)30-13-31-22)34-6-8-36-9-7-34/h1-5,10-13,21H,6-9H2,(H2,29,35)	ZYLBIZICFDLWPM-UHFFFAOYSA-N	315864	2-(7-Chlorothieno- [2,3-d}pyridazin-4-yl)- 2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.43 (d, J = 5.4, 1H), 7.86 (d, J = 5.4, 1H), 7.77(s, 1H), 7.74-7.67 (m, 2H), 7.56 (dd, J = 9.4, 3.1,1H), 7.50 (dd, J = 9.5, 2.5, 1H), 7.44-7.35 (m, 2H),7.19 (d, J = 2.4, 1H), 5.92 (s, 1H), 3.81-3.74 (m,4H), 3.47-3.40 (m, 4H).::US10172859, Example 291::US11065253, Example 291::US9732094, Example 291	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315864&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711726	383542534							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659845	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(n1)C(N)=O	InChI=1S/C25H22FN7O3/c26-18-4-1-14(22(25(28)35)20-11-29-12-21(32-20)24(27)34)9-17(18)23-16-3-2-15(10-19(16)30-13-31-23)33-5-7-36-8-6-33/h1-4,9-13,22H,5-8H2,(H2,27,34)(H2,28,35)	XBPHXCUOKRHJAU-UHFFFAOYSA-N	315865	6-{Carbamoyl-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methyl}- pyrazine-2-carboxylic acid amide1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 9.06 (s, 1H), 8.90 (s, 1H), 8.08-8.01 (m,1H), 7.99-7.93 (m, 1H), 7.85-7.77 (m, 2H),7.77-7.71 (m, 1H), 7.59 (dd, J = 9.4, 3.6, 1H),7.52 (dd, J = 9.5, 2.5, 1H), 7.46-7.39 (m, 1H),7.38-7.32 (m, 1H), 7.20 (d, J = 2.5, 1H), 5.39 (s,1H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H).::US10172859, Example 292::US11065253, Example 292::US9732094, Example 292	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315865&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711808	383542535							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659847	NC(=O)C(c1cccnc1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN5O2/c26-20-12-21(27)19(11-18(20)23(25(28)33)15-2-1-5-29-13-15)24-17-4-3-16(10-22(17)30-14-31-24)32-6-8-34-9-7-32/h1-5,10-14,23H,6-9H2,(H2,28,33)	FJSRWVIDUQOPMH-UHFFFAOYSA-N	315866	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridin-3- ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.49 (s, 1H), 8.46 (d, J = 3.9, 1H), 7.94 (s,1H), 7.74 (d, J = 9.5, 1H), 7.67 (d, J = 7.7, 1H), 7.66-7.63 (m, 1H), 7.56 (dd, J = 9.4, 4.8, 1H), 7.53 (s,J = 9.5, 2.4, 1H), 7.37 (dd, J = 7.9, 4.8, 1H), 7.33 (s,1H), 7.20 (d, J = 2.3, 1H), 5.41 (s, 1H), 3.81-3.74(m, 4H), 3.49-3.42 (m, 4H).::US10172859, Example 293::US11065253, Example 293::US9732094, Example 293	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315866&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954991	383542536							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659849	NC(=O)C(c1cccnc1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N5O2/c26-20-12-21(27)19(11-18(20)23(25(28)33)15-2-1-5-29-13-15)24-17-4-3-16(10-22(17)30-14-31-24)32-6-8-34-9-7-32/h1-5,10-14,23H,6-9H2,(H2,28,33)	VMDULKVFFKUUBT-UHFFFAOYSA-N	315867	2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridin-3- ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.53 (d, J = 2.3, 1H), 8.48 (dd, J = 4.8, 1.6, 1H),7.89 (s, 1H), 7.72 (dt, J = 8.0, 2.0, 1H), 7.61 (t,J = 8.2, 1H), 7.59-7.48 (m, 3H), 7.38 (dd, J = 7.9,4.7, 1H), 7.32 (s, 1H), 7.19 (d, J = 2.3, 1H), 5.31(s, 1H), 3.82-3.73 (m, 4H), 3.47-3.42 (m, 4H).::US10172859, Example 294::US11065253, Example 294::US9732094, Example 294	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315867&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711804	383542537							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659851	NC(=O)C(c1cccnc1)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN5O2/c26-21-6-3-16(23(25(27)32)17-2-1-7-28-14-17)12-20(21)24-19-5-4-18(13-22(19)29-15-30-24)31-8-10-33-11-9-31/h1-7,12-15,23H,8-11H2,(H2,27,32)	HARXJYPHARBMGT-UHFFFAOYSA-N	315868	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridin-3- ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.55 (s, 1H), 8.47 (s, 1H), 7.82 (s, 1H), 7.79(d, J = 8.0, 1H), 7.62-7.56 (m, 2H), 7.56-7.49 (m,2H), 7.45-7.35 (m, 2H), 7.25 (s, 1H), 7.20 (d,J = 2.0, 1H), 5.12 (s, 1H), 3.80-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 295::US11065253, Example 295::US9732094, Example 295	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315868&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954838	383542538							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659853	Cc1cncc(n1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-12-26-13-22(29-15)24(31)16-2-5-20(25)19(10-16)23-18-4-3-17(11-21(18)27-14-28-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	ORSZUBJYTOFBKJ-UHFFFAOYSA-N	315869	US10172859, Example 296::US11065253, Example 296::US9732094, Example 296::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.66 (s, 1H), 8.43 (s, 1H), 7.68-7.63 (m,2H), 7.54-7.49 (m, 2H), 7.42-7.35 (m, 1H),7.21-7.18 (m, 1H), 6.40 (d, J = 4.3, 1H), 5.87 (d,J = 4.3, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m,4H), 2.46 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315869&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954831	383542539							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659855	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(Cl)c1	InChI=1S/C25H21ClFN5O2/c26-17-9-16(12-29-13-17)23(25(28)33)15-1-4-21(27)20(10-15)24-19-3-2-18(11-22(19)30-14-31-24)32-5-7-34-8-6-32/h1-4,9-14,23H,5-8H2,(H2,28,33)	IVXXOGNVDFQXBW-UHFFFAOYSA-N	315870	2-(5-Chloro-pyridin- 3-yl)-2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.54 (d, J = 2.4, 1H), 8.52 (d, J = 1.9, 1H), 7.90-7.87 (m, 1H), 7.85 (s, 1H), 7.61 (tt, J = 6.9, 2.3,2H), 7.53 (qd, J = 9.4, 2.8, 2H), 7.47-7.39 (m, 1H),7.33 (s, 1H), 7.20 (d, J = 2.3, 1H), 5.16 (s, 1H),3.82-3.73 (m, 4H), 3.48-3.40 (m, 4H).::US10172859, Example 297::US11065253, Example 297::US9732094, Example 297	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315870&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711747	383542540							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659857	NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccc2nncn12	InChI=1S/C26H21ClFN7O2/c27-19-12-20(28)18(11-17(19)24(26(29)36)22-2-1-3-23-33-32-14-35(22)23)25-16-5-4-15(10-21(16)30-13-31-25)34-6-8-37-9-7-34/h1-5,10-14,24H,6-9H2,(H2,29,36)	MUPNGTJETJQOSB-UHFFFAOYSA-N	315871	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.21 (d,J = 0.8, 1H), 9.08 (s, 1H), 8.13 (s, 1H), 7.88 (d,J = 9.5, 1H), 7.79 (d, J = 9.2, 1H), 7.73 (s, 1H), 7.57-7.48 (m, 3H), 7.38 (dd, J = 9.2, 6.9, 1H), 7.19 (d,J = 2.3, 1H), 6.57 (d, J = 6.9, 1H), 5.84 (s, 1H), 3.80-3.75 (m, 4H), 3.48-3.42 (m, 4H).::US10172859, Example 298::US9732094, Example 298	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954996	383542541							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659859	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C26H22FN7O2/c27-20-6-3-16(23(26(28)35)25-22-2-1-7-34(22)32-15-31-25)12-19(20)24-18-5-4-17(13-21(18)29-14-30-24)33-8-10-36-11-9-33/h1-7,12-15,23H,8-11H2,(H2,28,35)	ZMIMJRGRWXTILZ-UHFFFAOYSA-N	315872	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyrrolo- [2,1-f][1,2,4]triazin-4- ylacetamide::US10172859, Example 299::US11065253, Example 299::US9732094, Example 299	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315872&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711729	383542542							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659861	NC(=O)C(c1cccnn1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H20ClFN6O2/c25-18-12-19(26)17(11-16(18)22(24(27)33)20-2-1-5-30-31-20)23-15-4-3-14(10-21(15)28-13-29-23)32-6-8-34-9-7-32/h1-5,10-13,22H,6-9H2,(H2,27,33)	GVAJWRHXZHKFPU-UHFFFAOYSA-N	315873	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyridazin- 3-ylacetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (dd,J = 4.9, 1.6, 1H), 9.10 (s, 1H), 8.03 (s, 1H), 7.76(d, J = 9.6, 1H), 7.71 (d, J = 7.6, 1H), 7.65 (dd,J = 8.5, 4.9, 1H), 7.60 (dd, J = 9.4, 3.4, 1H), 7.53(dd, J = 5.6, 2.1, 1H), 7.52 (dd, J = 4.7, 2.0, 1H),7.43 (s, 1H), 7.20 (d, J = 2.5, 1H), 5.78 (s, 1H),3.78 (dd, J = 5.8, 4.0, 4H), 3.46 (dd, J = 6.0, 3.9, 4H).::US10172859, Example 300::US11065253, Example 300::US9732094, Example 300	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954908	383542543							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659863	Cc1cnc(C(C(N)=O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C26H24ClFN6O2/c1-14-12-30-24(15(2)33-14)23(26(29)35)18-10-19(21(28)11-20(18)27)25-17-4-3-16(9-22(17)31-13-32-25)34-5-7-36-8-6-34/h3-4,9-13,23H,5-8H2,1-2H3,(H2,29,35)	YREBEWXOGBLYAA-UHFFFAOYSA-N	315874	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3,5- dimethyl-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.25 (s, 1H), 7.75-7.69 (m, 2H), 7.58 (dd,J = 9.4, 3.0, 1H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.47 (d,J = 7.7, 1H), 7.28 (s, 1H), 7.19 (d, J = 2.4, 1H), 5.60(s, 1H), 3.81-3.74 (m, 4H), 3.49-3.42 (m, 4H),2.49 (s, 3H), 2.41 (s, 3H).::US10172859, Example 301::US11065253, Example 301::US9732094, Example 301	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315874&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954954	383542544							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659865	Nc1cncc(n1)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H21FN6O2/c24-18-4-1-14(23(31)20-11-26-12-21(25)29-20)9-17(18)22-16-3-2-15(10-19(16)27-13-28-22)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2,(H2,25,29)	NIRGTHULFDHQGA-UHFFFAOYSA-N	315875	(6-Amino-pyrazin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.91 (s, 1H), 7.74 (s, 1H), 7.63-7.56 (m,2H), 7.54-7.51 (m, 2H), 7.39-7.34 (m, 1H),7.21-7.19 (m, 1H), 6.36 (s, 2H), 6.10 (d, J = 4.3,1H), 5.60 (d, J = 4.3, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H).::US10172859, Example 302::US11065253, Example 302::US9732094, Example 302	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315875&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954786	383542545							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659867	Cc1nccnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-23(29-7-6-28-15)22(25(27)33)19-12-16(2-5-20(19)26)24-18-4-3-17(13-21(18)30-14-31-24)32-8-10-34-11-9-32/h2-7,12-14,22H,8-11H2,1H3,(H2,27,33)	HFSXUJIMPFGNPH-UHFFFAOYSA-N	315876	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.43-8.37 (m, 2H), 7.87 (d, J = 9.4, 1H), 7.80(s, 1H), 7.75-7.65 (m, 3H), 7.51 (dd, J = 9.5, 2.6,1H), 7.33 (s, 1H), 7.19 (d, J = 2.5, 1H), 5.71 (s,1H), 3.85-3.74 (m, 4H), 3.52-3.39 (m, 4H),2.55 (s, 3H).::US10172859, Example 303::US11065253, Example 303::US9732094, Example 303	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954878	383542546							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659869	COc1nccnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O3/c1-34-25-23(28-6-7-29-25)21(24(27)33)18-12-15(2-5-19(18)26)22-17-4-3-16(13-20(17)30-14-31-22)32-8-10-35-11-9-32/h2-7,12-14,21H,8-11H2,1H3,(H2,27,33)	PYCHWQUCZXHTRJ-UHFFFAOYSA-N	315877	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 8.12 (d, J = 2.8, 1H), 8.10 (d, J = 2.8, 1H), 7.89(d, J = 9.4, 1H), 7.79-7.75 (m, 1H), 7.73-7.69 (m,2H), 7.67 (d, J = 8.1, 1H), 7.52 (dd, J = 9.5, 2.6, 1H),7.27-7.23 (m, 1H), 7.20 (d, J = 2.6, 1H), 5.71 (s,1H), 3.95 (s, 3H), 3.81-3.75 (m, 4H), 3.49-3.41(m, 4H).::US10172859, Example 304::US11065253, Example 304::US9732094, Example 304	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315877&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954818	383542547							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659871	COc1nccnc1C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-34-25-23(28-6-7-29-25)21(24(27)33)15-2-5-19(26)18(12-15)22-17-4-3-16(13-20(17)30-14-31-22)32-8-10-35-11-9-32/h2-7,12-14,21H,8-11H2,1H3,(H2,27,33)	WTJREBFFELNABQ-UHFFFAOYSA-N	315878	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.13 (d, J = 2.8, 1H), 8.10 (d, J = 2.8, 1H), 7.63(dd, J = 9.4, 2.8, 1H), 7.61-7.52 (m, 4H), 7.41-7.35 (m, 1H), 7.20 (d, J = 2.4, 1H), 7.11 (s, 1H),5.34 (s, 1H), 3.93 (s, 3H), 3.82-3.74 (m, 4H),3.48-3.41 (m, 4H).::US10172859, Example 305::US11065253, Example 305::US9732094, Example 305	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315878&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954938	383542548							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659873	COc1ccc(nn1)C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O3/c1-35-22-5-4-20(31-32-22)23(25(28)34)16-11-17(19(27)12-18(16)26)24-15-3-2-14(10-21(15)29-13-30-24)33-6-8-36-9-7-33/h2-5,10-13,23H,6-9H2,1H3,(H2,28,34)	SVGLXBJVNLMNGP-UHFFFAOYSA-N	315879	2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxy-pyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.90 (s, 1H), 7.71 (t, J = 8.2, 1H), 7.61-7.49(m, 4H), 7.37 (s, 1H), 7.20 (d, J = 2.4, 1H), 7.18 (d,J = 9.2, 1H), 5.57 (s, 1H), 4.00 (s, 3H), 3.81-3.74(m, 4H), 3.49-3.41 (m, 4H).::US10172859, Example 306::US11065253, Example 306::US9732094, Example 306	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315879&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954932	383542549							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659875	COc1nnccc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-35-25-16(4-5-31-32-25)22(24(28)34)17-11-18(20(27)12-19(17)26)23-15-3-2-14(10-21(15)29-13-30-23)33-6-8-36-9-7-33/h2-5,10-13,22H,6-9H2,1H3,(H2,28,34)	MYBWUZUNIOXSID-UHFFFAOYSA-N	315880	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxypyridazin-4- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.80 (d, J = 4.7, 1H), 8.02 (s, 1H), 7.80 (d,J = 9.5, 1H), 7.59 (dd, J = 9.4, 3.3, 1H), 7.53 (dd,J = 9.5, 2.5, 1H), 7.46 (d, J = 7.5, 1H), 7.42 (s, 1H),7.20 (d, J = 2.4, 1H), 7.08 (dd, J = 4.7, 0.5, 1H), 5.46(s, 1H), 4.07 (s, 3H), 3.80-3.76 (m, 4H), 3.49-3.43 (m, 4H).::US10172859, Example 307::US11065253, Example 307::US9732094, Example 307	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315880&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954902	383542550							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659877	COc1ccc(nn1)C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-34-22-7-6-20(30-31-22)23(25(27)33)15-2-5-19(26)18(12-15)24-17-4-3-16(13-21(17)28-14-29-24)32-8-10-35-11-9-32/h2-7,12-14,23H,8-11H2,1H3,(H2,27,33)	ISTYTDDGDVSFKS-UHFFFAOYSA-N	315881	2-[4-Fluoro-3-(7- morpolin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxypyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.87 (s, 1H), 7.67 (d, J = 9.2, 1H), 7.64-7.57(m, 2H), 7.57-7.49 (m, 2H), 7.46-7.38 (m, 1H),7.31 (s, 1H), 7.20 (d, J = 2.2, 1H), 7.18 (d, J = 9.2,1H), 5.40 (s, 1H), 4.00 (s, 3H), 3.78 (dd, J = 5.8,3.9, 4H), 3.44 (dd, J = 5.8, 4.1, 4H).::US10172859, Example 308::US11065253, Example 308::US9732094, Example 308	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315881&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954945	383542551							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659879	NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C26H21ClFN7O2/c27-19-12-20(28)18(11-17(19)23(26(29)36)25-22-2-1-5-35(22)33-14-32-25)24-16-4-3-15(10-21(16)30-13-31-24)34-6-8-37-9-7-34/h1-5,10-14,23H,6-9H2,(H2,29,36)	LXBZRTFPUMGGNZ-UHFFFAOYSA-N	315882	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[3H- pyrrolo[2,1-f][1,2,4]- triazin-(4E)-ylidene]- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 13.76 (d,J = 3.9, 1H), 9.07 (s, 1H), 7.86 (d, J = 9.7, 1H), 7.84-7.76 (m, 2H), 7.56 (d, J = 7.8, 1H), 7.51 (dd,J = 9.5, 2.5, 1H), 7.32 (dd, J = 2.7, 1.7, 1H), 7.18 (d,J = 2.4, 1H), 6.99 (s, 1H), 6.37 (s, 1H), 6.26 (dd,J = 4.4, 2.7, 1H), 4.87 (dd, J = 4.4, 1.7, 1H), 3.81-3.74 (m, 4H), 3.49-3.42 (m, 4H).::US10172859, Example 309::US11065253, Example 309::US9732094, Example 309	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315882&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966399	383542552							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659881	COc1ccc(nn1)C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O3/c1-34-22-7-6-20(30-31-22)23(25(27)33)18-12-15(2-5-19(18)26)24-17-4-3-16(13-21(17)28-14-29-24)32-8-10-35-11-9-32/h2-7,12-14,23H,8-11H2,1H3,(H2,27,33)	JNCOXIXWPDKVLE-UHFFFAOYSA-N	315883	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxy-pyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 7.97 (s, 1H), 7.89-7.85 (m, 2H), 7.73 (dd,J = 8.2, 2.1, 1H), 7.70 (d, J = 8.2, 1H), 7.52 (dd,J = 9.5, 2.6, 1H), 7.46 (d, J = 9.2, 1H), 7.39 (s, 1H),7.21 (d, J = 2.5, 1H), 7.18 (d, J = 9.2, 1H), 5.72 (s,1H), 4.01 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.42(m, 4H).::US10172859, Example 310::US11065253, Example 310::US9732094, Example 310	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315883&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954980	383542553							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659883	Cn1nc(ccc1=O)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-32-22(34)5-4-20(31-32)23(25(28)35)16-11-17(19(27)12-18(16)26)24-15-3-2-14(10-21(15)29-13-30-24)33-6-8-36-9-7-33/h2-5,10-13,23H,6-9H2,1H3,(H2,28,35)	JMVHOQVMAZGVSV-UHFFFAOYSA-N	315884	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1-methyl- 6-oxo-1,6-dihydro- pyridazin-3-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.92 (s, 1H), 7.76 (d, J = 9.5, 1H), 7.68 (d,J = 7.5, 1H), 7.58 (dd, J = 9.4, 3.1, 1H), 7.54 (dd,J = 9.5, 2.5, 1H), 7.41 (s, 1H), 7.33 (d, J = 9.6, 1H),7.21 (d, J = 2.4, 1H), 6.90 (d, J = 9.6, 1H), 5.33 (s,1H), 3.81-3.75 (m, 4H), 3.59 (s, 3H), 3.49-3.42(m, 4H).::US10172859, Example 311::US11065253, Example 311::US9732094, Example 311	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315884&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954843	383542554							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659885	Cn1c(cccc1=O)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H23ClFN5O3/c1-32-22(3-2-4-23(32)34)24(26(29)35)17-12-18(20(28)13-19(17)27)25-16-6-5-15(11-21(16)30-14-31-25)33-7-9-36-10-8-33/h2-6,11-14,24H,7-10H2,1H3,(H2,29,35)	HIJPXJUNOMZZGM-UHFFFAOYSA-N	315885	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1-methyl- 6-oxo-1,6-dihydro- pyridin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.04 (s, 1H), 7.83 (d, J = 9.4, 1H), 7.62-7.44(m, 3H), 7.42-7.27 (m, 2H), 7.19 (d, J = 2.4, 1H),6.36 (dd, J = 9.1, 1.3, 1H), 5.90 (dd, J = 7.1, 1.3, 1H),5.48 (s, 1H), 3.77 (dd, J = 5.8, 4.0, 4H), 3.52-3.42(m, 4H), 3.40 (s, 3H).::US10172859, Example 312::US11065253, Example 312::US9732094, Example 312	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315885&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954733	383542555							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659887	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C25H21ClFN5O2/c26-19-2-1-7-29-24(19)22(25(28)33)15-3-6-20(27)18(12-15)23-17-5-4-16(13-21(17)30-14-31-23)32-8-10-34-11-9-32/h1-7,12-14,22H,8-11H2,(H2,28,33)	ODLAGNXUZAQEJQ-UHFFFAOYSA-N	315886	2-(3-Chloro-pyridin- 2-yl)-2-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.51 (dd, J = 4.7, 1.5, 1H), 7.93 (dd, J = 8.1,1.5, 1H), 7.64 (dd, J = 9.4, 2.9, 1H), 7.61-7.53 (m,4H), 7.39 (dd, J = 9.9, 8.7, 1H), 7.36 (dd, J = 8.1,4.7, 1H), 7.21 (d, J = 2.5, 1H), 7.17 (s, 1H), 5.53(s, 1H), 3.84-3.73 (m, 4H), 3.50-3.41 (m, 4H).::US10172859, Example 313::US11065253, Example 313::US9732094, Example 313	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315886&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711751	383542556							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659889	Cc1ncc(nc1C)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O2/c1-15-16(2)30-23(13-27-15)25(32)17-3-6-21(26)20(11-17)24-19-5-4-18(12-22(19)28-14-29-24)31-7-9-33-10-8-31/h3-6,11-14,25,32H,7-10H2,1-2H3	IEKSFLLJQVYYRD-UHFFFAOYSA-N	315887	(5,6-Dimethyl- pyrazin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-6) ppm = 9.09 (s,1H), 8.51 (s, 1H), 7.66-7.61 (m, 2H), 7.54-7.49(m, 2H), 7.40-7.35 (m, 1H), 7.21-7.19 (m, 1H),6.32 (d, J = 4.2, 1H), 5.84 (d, J = 4.0, 1H), 3.80-3.75 (m, 4H), 3.46-3.42 (m, 4H), 2.45 (s, 3H),2.44 (s, 3H).::US10172859, Example 314::US11065253, Example 314::US9732094, Example 314	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315887&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954958	383542557							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659891	NC(=O)C(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1Cl	InChI=1S/C24H20Cl2N6O2/c25-18-4-1-14(11-17(18)20(24(27)33)22-23(26)29-6-5-28-22)21-16-3-2-15(12-19(16)30-13-31-21)32-7-9-34-10-8-32/h1-6,11-13,20H,7-10H2,(H2,27,33)	LGURFCDOKAGGDY-UHFFFAOYSA-N	315888	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-chloro- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.60 (d, J = 2.5, 1H), 8.45 (d, J = 2.5, 1H), 7.97-7.91 (m, 1H), 7.88 (d, J = 9.5, 1H), 7.75 (dd,J = 8.3, 2.1, 1H), 7.71 (d, J = 8.2, 1H), 7.66 (d,J = 2.1, 1H), 7.53 (dd, J = 9.5, 2.6, 1H), 7.47-7.42(m, 1H), 7.22-7.19 (m, 1H), 5.87 (s, 1H), 3.81-3.76 (m, 4H), 3.47-3.42 (m, 4H).::US10172859, Example 315::US11065253, Example 315::US9732094, Example 315	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315888&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954816	383542558							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659893	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O3/c1-35-25-23(29-4-5-30-25)21(24(28)34)16-11-17(19(27)12-18(16)26)22-15-3-2-14(10-20(15)31-13-32-22)33-6-8-36-9-7-33/h2-5,10-13,21H,6-9H2,1H3,(H2,28,34)	RKXNBPNEHZAEBV-UHFFFAOYSA-N	315894	2-[2,4-Difluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-2-(3-methoxypyrazin-2-yl)-acetamide ::US10172859, Example 319::US11065253, Example 319::US9732094, Example 316	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315894	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315894&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696606	383542564							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659895	Cn1nc(ccc1=O)C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O3/c1-31-22(33)7-6-20(30-31)23(25(27)34)15-2-5-19(26)18(12-15)24-17-4-3-16(13-21(17)28-14-29-24)32-8-10-35-11-9-32/h2-7,12-14,23H,8-11H2,1H3,(H2,27,34)	AJGVVTLBHUTRNF-UHFFFAOYSA-N	315890	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1-methyl- 6-oxo-1,6-dihydro- pyridazin-3-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.86 (s, 1H), 7.64-7.50 (m, 4H), 7.47 (d,J = 9.6, 1H), 7.44 (dd, J = 9.8, 8.5, 1H), 7.34 (s, 1H),7.20 (d, J = 2.2, 1H), 6.90 (d, J = 9.6, 1H), 5.05 (s,1H), 3.83-3.73 (m, 4H), 3.61 (s, 3H), 3.44 (t,J = 4.9, 4H).::US10172859, Example 317::US11065253, Example 317::US9732094, Example 317	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315890&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954966	383542560							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659897	Cc1cnc(C(C(N)=O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C26H25FN6O2/c1-15-13-29-24(16(2)32-15)23(26(28)34)17-3-6-21(27)20(11-17)25-19-5-4-18(12-22(19)30-14-31-25)33-7-9-35-10-8-33/h3-6,11-14,23H,7-10H2,1-2H3,(H2,28,34)	NRRQWZVQONPIET-UHFFFAOYSA-N	315893	2-(3,5-Dimethyl- pyrazin-2-yl)-2-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.29 (s, 1H), 7.60 (dd, J = 9.5, 2.9, 1H), 7.59-7.55 (m, 2H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.50 (s,1H), 7.42-7.33 (m, 1H), 7.20 (d, J = 2.5, 1H), 7.15(s, 1H), 5.35 (s, 1H), 3.78 (dd, J = 5.8, 4.0, 4H),3.44 (dd, J = 6.0, 3.9, 4H), 2.49 (s, 3H), 2.41 (s,3H).::US10172859, Example 318::US11065253, Example 318::US9732094, Example 318	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315893	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315893&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711771	383542563							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659899	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O3/c1-35-25-23(29-4-5-30-25)21(24(28)34)16-11-17(19(27)12-18(16)26)22-15-3-2-14(10-20(15)31-13-32-22)33-6-8-36-9-7-33/h2-5,10-13,21H,6-9H2,1H3,(H2,28,34)	RKXNBPNEHZAEBV-UHFFFAOYSA-N	315894	2-[2,4-Difluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-2-(3-methoxypyrazin-2-yl)-acetamide ::US10172859, Example 319::US11065253, Example 319::US9732094, Example 316	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315894	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315894&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696606	383542564							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659901	COc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-35-25-23(29-4-5-30-25)21(24(28)34)16-11-17(19(27)12-18(16)26)22-15-3-2-14(10-20(15)31-13-32-22)33-6-8-36-9-7-33/h2-5,10-13,21H,6-9H2,1H3,(H2,28,34)	YUXKXBCAYRFJNK-UHFFFAOYSA-N	315895	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3- methoxy-pyrazin-2- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.12 (d, J = 2.8, 1H), 8.09 (d, J = 2.8, 1H), 7.78(s, 1H), 7.72 (d, J = 9.6, 1H), 7.60 (dd, J = 9.4, 3.1,1H), 7.55 (dd, J = 9.5, 2.5, 1H), 7.51 (d, J = 7.6, 1H),7.26 (s, 1H), 7.20 (d, J = 2.4, 1H), 5.65 (s, 1H),3.95 (s, 3H), 3.86-3.66 (m, 4H), 3.56-3.37 (m,4H).::US10172859, Example 320::US11065253, Example 320::US9732094, Example 320	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315895	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315895&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954886	383542565							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659903	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1c(F)cncc1F	InChI=1S/C25H20F3N5O2/c26-18-4-1-14(22(25(29)34)23-19(27)11-30-12-20(23)28)9-17(18)24-16-3-2-15(10-21(16)31-13-32-24)33-5-7-35-8-6-33/h1-4,9-13,22H,5-8H2,(H2,29,34)	IJRREKAUYFBFNQ-UHFFFAOYSA-N	315897	2-(3,5-Difluoro- pyridin-4-yl)-2-[2- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.50 (s, 2H), 7.59 (s, 1H), 7.58-7.49 (m,4H), 7.46-7.37 (m, 2H), 7.20 (d, J = 2.2, 1H), 5.42(s, 1H), 3.87-3.64 (m, 4H), 3.59-3.40 (m, 4H).::US10172859, Example 321::US11065253, Example 321::US9732094, Example 321	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315897&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711728	383542567							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659905	NC(=O)C(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc(F)c1Cl	InChI=1S/C25H20ClF2N5O2/c26-23-18(11-30-12-20(23)28)22(25(29)34)14-1-4-19(27)17(9-14)24-16-3-2-15(10-21(16)31-13-32-24)33-5-7-35-8-6-33/h1-4,9-13,22H,5-8H2,(H2,29,34)	OVKBRTLIPKHGGE-UHFFFAOYSA-N	315898	2-(4-Chloro-5-fluoro- pyridin-3-yl)-2-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (d,J = 2.3, 1H), 8.65 (s, 1H), 8.33 (s, 1H), 7.94 (s,1H), 7.61-7.50 (m, 4H), 7.44 (dt, J = 20.5, 9.0,2H), 7.20 (d, J = 2.1, 1H), 5.44 (s, 1H), 3.80-3.75(m, 4H), 3.47-3.42 (m, 4H).::US10172859, Example 322::US11065253, Example 322::US9732094, Example 322	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315898	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315898&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954801	383542568							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659907	NC(=O)C(c1ccc2nccn2n1)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H21ClFN7O2/c27-19-13-20(28)18(12-17(19)24(26(29)36)21-3-4-23-30-5-6-35(23)33-21)25-16-2-1-15(11-22(16)31-14-32-25)34-7-9-37-10-8-34/h1-6,11-14,24H,7-10H2,(H2,29,36)	OJEWVMZBLXICGN-UHFFFAOYSA-N	315899	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-imidazo- [1,2-b]pyridazin-6-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (d,J = 10.0, 1H), 8.24 (s, 1H), 8.08 (d, J = 9.5, 1H),8.02 (s, 1H), 7.79 (d, J = 9.5, 1H), 7.76 (d, J = 1.2,1H), 7.72 (d, J = 7.6, 1H), 7.60 (dd, J = 9.5, 3.2, 1H),7.53 (dd, J = 9.5, 2.5, 1H), 7.47 (s, 1H), 7.22 (d,J = 2.5, 1H), 7.11 (d, J = 9.5, 1H), 5.61 (s, 1H), 3.81-3.74 (m, 4H), 3.49-3.42 (m, 4H).::US10172859, Example 323::US11065253, Example 323::US9732094, Example 323	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315899	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315899&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954761	383542569							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659909	Cc1nccnc1C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O2/c1-14-23(30-5-4-29-14)22(25(28)34)17-11-18(20(27)12-19(17)26)24-16-3-2-15(10-21(16)31-13-32-24)33-6-8-35-9-7-33/h2-5,10-13,22H,6-9H2,1H3,(H2,28,34)	YYPSKFJTJFGDAL-UHFFFAOYSA-N	315900	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.40 (d, J = 2.5, 1H), 8.38 (d, J = 2.5, 1H), 7.80(s, 1H), 7.73 (d, J = 9.5, 1H), 7.59 (dd, J = 9.5, 3.0,1H), 7.54 (dd, J = 9.5, 2.5, 1H), 7.48 (d, J = 7.6, 1H),7.34 (s, 1H), 7.19 (d, J = 2.4, 1H), 5.66 (s, 1H),3.78 (dd, J = 5.8, 4.0, 4H), 3.45 (dd, J = 5.9, 3.9, 4H),2.55 (s, 3H).::US10172859, Example 324::US11065253, Example 324::US9732094, Example 324	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315900	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315900&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954876	383542570							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659911	COc1ccc(nn1)C(C(N)=O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN6O3/c1-35-22-5-4-20(31-32-22)23(25(28)34)16-11-17(19(27)12-18(16)26)24-15-3-2-14(10-21(15)29-13-30-24)33-6-8-36-9-7-33/h2-5,10-13,23H,6-9H2,1H3,(H2,28,34)	DYZAPEQQSGHKFC-UHFFFAOYSA-N	315901	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(6- methoxypyridazin-3- yl)acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 7.96 (s, 1H), 7.75 (d, J = 9.5, 1H), 7.71 (d,J = 7.6, 1H), 7.63-7.51 (m, 2H), 7.47 (d, J = 9.21H), 7.39 (s, 1H), 7.21 (d, J = 2.4, 1H), 7.17 (d,J = 9.2, 1H), 5.67 (s, 1H), 4.00 (s, 3H), 3.82-3.74(m, 4H), 3.50-3.42 (m, 4H).::US10172859, Example 325::US9732094, Example 325	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315901	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315901&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954997	383542571							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659913	Cn1nc(ccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-29-22(31)7-6-20(28-29)24(32)15-2-5-19(25)18(12-15)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,32H,8-11H2,1H3	HTZWBDYETOMOMW-UHFFFAOYSA-N	315902	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-2-methyl-2H- pyridazin-3-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.66-7.60 (m, 2H), 7.55-7.49 (m, 2H),7.47 (d, J = 9.6, 1H), 7.44-7.39 (m, 1H), 7.21-7.19 (m, 1H), 6.93 (d, J = 9.6, 1H), 6.46 (d, J = 4.3,1H), 5.66 (d, J = 4.3, 1H), 3.80-3.75 (m, 4H), 3.62(s, 3H), 3.46-3.42 (m, 4H).::US10172859, Example 326::US11065253, Example 326::US9732094, Example 326	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315902	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315902&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954783	383542572							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659915	Cc1nccnc1C(C(N)=O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN6O2/c1-15-23(29-7-6-28-15)22(25(27)33)16-2-5-20(26)19(12-16)24-18-4-3-17(13-21(18)30-14-31-24)32-8-10-34-11-9-32/h2-7,12-14,22H,8-11H2,1H3,(H2,27,33)	SXTFNSCSKUHTAF-UHFFFAOYSA-N	315903	2-[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.41 (d, J = 2.4, 1H), 8.38 (d, J = 2.6, 1H), 7.64-7.51 (m, 5H), 7.38 (dd, J = 10.6, 8.5, 1H), 7.21-7.16 (m, 2H), 5.41 (s, 1H), 3.83-3.74 (m, 4H),3.46-3.40 (m, 4H), 2.54 (s, 3H).::US10172859, Example 327::US11065253, Example 327::US9732094, Example 327	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315903&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954849	383542573							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659917	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccc2ccoc12	InChI=1S/C26H21FN4O3/c27-21-4-1-17(25(32)24-26-16(5-7-28-24)6-10-34-26)13-20(21)23-19-3-2-18(14-22(19)29-15-30-23)31-8-11-33-12-9-31/h1-7,10,13-15,25,32H,8-9,11-12H2	XGIZNDWBXPNXFQ-UHFFFAOYSA-N	315904	US10172859, Example 328::US11065253, Example 328::US9732094, Example 328::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-c]- pyridin-7-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.32 (d, J = 5.2, 1H), 8.21 (d, J = 2.2, 1H), 7.74-7.67 (m, 2H), 7.64 (d, J = 5.2, 1H), 7.52-7.49 (m,2H), 7.36 (dd, J = 9.9, 8.4, 1H), 7.22-7.16 (m, 1H),7.06 (d, J = 2.2, 1H), 6.32 (d, J = 5.0, 1H), 6.25 (d,J = 5.0, 1H), 3.80-3.75 (m, 4H), 3.46-3.41 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315904&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966400	383542574							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659919	Cc1nccnc1C(C(N)=O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N6O2/c1-14-23(30-5-4-29-14)22(25(28)34)17-11-18(20(27)12-19(17)26)24-16-3-2-15(10-21(16)31-13-32-24)33-6-8-35-9-7-33/h2-5,10-13,22H,6-9H2,1H3,(H2,28,34)	GFGSCOPSJYQYMM-UHFFFAOYSA-N	315905	2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(3-methyl- pyrazin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.41 (d, J = 2.6, 1H), 8.39 (d, J = 2.7, 1H), 7.77-7.68 (m, 1H), 7.61 (dd, J = 9.4, 3.1, 1H), 7.59-7.47 (m, 3H), 7.32 (s, 1H), 7.19 (d, J = 2.5, 1H),5.57 (s, 1H), 3.84-3.74 (m, 4H), 3.48-3.41 (m,4H), 2.55 (s, 3H).::US10172859, Example 329::US11065253, Example 329::US9732094, Example 329	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315905&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954863	383542575							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659921	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc(O)c1Cl	InChI=1S/C23H19Cl2N5O3/c24-17-4-1-13(9-16(17)22(31)21-19(25)23(32)29-12-28-21)20-15-3-2-14(10-18(15)26-11-27-20)30-5-7-33-8-6-30/h1-4,9-12,22,31H,5-8H2,(H,28,29,32)	NFMQAKHWNHWLMS-UHFFFAOYSA-N	315906	5-Chloro-6-{[2- chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrimidin-4-ol1H NMR (500 MHz, DMSO-d6) ppm = 13.06 (s,1H), 9.09 (s, 1H), 8.22-8.14 (m, 2H), 7.97 (d,J = 9.4, 1H), 7.71 (dd, J = 8.2, 2.2, 1H), 7.62-7.56(m, 2H), 7.22 (d, J = 2.6, 1H), 6.46 (d, J = 5.5, 1H),6.31 (d, J = 5.5, 1H), 3.83-3.77 (m, 4H), 3.48-3.43 (m, 4H).::US10172859, Example 330::US11065253, Example 330::US9732094, Example 330	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137002407	383542576							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659923	Cc1nccnc1\C(C(O)=O)=C1\C=CC(=O)C(=C1)c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21N5O4/c1-15-23(27-7-6-26-15)22(25(32)33)16-2-5-21(31)19(12-16)24-18-4-3-17(13-20(18)28-14-29-24)30-8-10-34-11-9-30/h2-7,12-14H,8-11H2,1H3,(H,32,33)/b22-16+	VDDZZCZXKACKKC-CJLVFECKSA-N	315907	(3-methyl-pyrazin-2- yl)-[3-(7-morpholin-4- ylquinazolin-4-yl)-4- oxocyclohexa-2,5- dien-(E)-ylidene]- acetic acid1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 8.70 (d, J = 2.5, 1H), 8.56 (d, J = 2.6, 1H), 8.01(dd, J = 8.8, 2.3, 1H), 7.84 (d, J = 2.3, 1H), 7.48 (d,J = 1.4, 2H), 7.38 (d, J = 8.8, 1H), 7.17-7.14 (m,1H), 3.81-3.74 (m, 4H), 3.45-3.39 (m, 4H),2.55 (s, 3H).::US10172859, Example 331::US11065253, Example 331::US9732094, Example 331	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315907	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315907&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954825	383542577							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659925	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccsc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(24(32)23-25-16(5-10-34-25)13-29-30-23)11-19(20)22-18-3-2-17(12-21(18)27-14-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	OBVAOTOESQVABX-UHFFFAOYSA-N	315908	US10172859, Example 332::US11065253, Example 332::US9732094, Example 332::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.56 (s,1H), 9.08 (s, 1H), 8.26 (d, J = 5.4, 1H), 7.79-7.72(m, 2H), 7.70 (d, J = 5.4, 1H), 7.51-7.44 (m, 2H),7.43-7.35 (m, 1H), 7.21-7.16 (m, 1H), 7.10 (d,J = 3.8, 1H), 6.38 (d, J = 3.9, 1H), 3.82-3.74 (m,4H), 3.47-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315908	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315908&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954809	383542578							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659927	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(25(32)24-18-5-10-34-22(18)13-29-30-24)11-19(20)23-17-3-2-16(12-21(17)27-14-28-23)31-6-8-33-9-7-31/h1-5,10-14,25,32H,6-9H2	AHYKWBDALRQZLR-UHFFFAOYSA-N	315909	US10172859, Example 333::US11065253, Example 333::US9732094, Example 333::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.84 (d,J = 0.6, 1H), 9.08 (s, 1H), 8.28 (d, J = 5.3, 1H), 7.89(dd, J = 5.4, 0.7, 1H), 7.75-7.67 (m, 2H), 7.49 (dd,J = 9.4, 2.4, 1H), 7.45 (dd, J = 9.4, 2.9, 1H), 7.42-7.34 (m, 1H), 7.19 (d, J = 2.3, 1H), 6.82 (s, 1H),6.42 (s, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315909&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954762	383542579							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659929	Cc1cc(C(C(N)=O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)n(C)c(=O)c1	InChI=1S/C27H25ClFN5O3/c1-15-9-23(33(2)24(35)10-15)25(27(30)36)18-12-19(21(29)13-20(18)28)26-17-4-3-16(11-22(17)31-14-32-26)34-5-7-37-8-6-34/h3-4,9-14,25H,5-8H2,1-2H3,(H2,30,36)	LOAVXRSZRSGZNK-UHFFFAOYSA-N	315910	2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(1,4- dimethyl-6-oxo-1,6- dihydropyridin-2-yl)- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.10-7.99 (m, 1H), 7.85 (d, J = 9.4, 1H), 7.58-7.49 (m, 3H), 7.34 (d, J = 7.4, 1H), 7.24-7.17 (m,1H), 6.22-6.15 (m, 1H), 5.79-5.77 (m, 1H),5.47 (s, 1H), 3.82-3.75 (m, 4H), 3.46 (t, J = 5.0,4H), 3.36 (s, 3H), 2.05 (s, 3H).::US10172859, Example 334::US11065253, Example 334::US9732094, Example 334	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315910&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954850	383542580							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659931	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccoc12	InChI=1S/C25H20FN5O3/c26-20-4-1-15(24(32)23-25-16(5-8-34-25)13-29-30-23)11-19(20)22-18-3-2-17(12-21(18)27-14-28-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	PRQMAIDTXMROEL-UHFFFAOYSA-N	315911	US10172859, Example 335::US11065253, Example 335::US9732094, Example 335::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.59 (s,1H), 9.09 (s, 1H), 8.37 (d, J = 2.1, 1H), 7.82-7.70(m, 2H), 7.54-7.47 (m, 2H), 7.40 (dd, J = 9.8, 8.6,1H), 7.23-7.16 (m, 2H), 6.69 (d, J = 4.6, 1H), 6.40(d, J = 4.6, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315911&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696509	383542581							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659933	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccoc12	InChI=1S/C25H19F2N5O3/c26-19-11-20(27)18(24(33)23-25-14(3-6-35-25)12-30-31-23)10-17(19)22-16-2-1-15(9-21(16)28-13-29-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JFAVIPWOVRTGDI-UHFFFAOYSA-N	315912	US10172859, Example 336::US11065253, Example 336::US9732094, Example 336::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.63 (s,1H), 9.14 (s, 1H), 8.41 (d, J = 2.1, 1H), 8.10 (t,J = 8.1, 1H), 7.63 (dd, J = 9.4, 3.0, 1H), 7.58 (dd,J = 9.4, 2.5, 1H), 7.45 (t, J = 10.1, 1H), 7.27-7.19(m, 2H), 6.82 (d, J = 5.3, 1H), 6.63 (d, J = 5.3, 1H),3.83-3.77 (m, 4H), 3.50-3.45 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315912&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954885	383542582							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659935	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1n[nH]c(=O)c2ccsc12			315913	7-[[4-Fluoro-3-(7- morpholino- quinazolin-4-yl)- phenyl]hydroxy- methyl]-5H-thieno- [2,3-d}pyridazin-4- one1H NMR (500 MHz, DMSO-d6) ppm = 12.73 (s,1H), 9.10 (s, 1H), 8.04 (d, J = 5.3, 1H), 7.74-7.63(m, 2H), 7.59 (d, J = 5.2, 1H), 7.53-7.45 (m, 2H),7.44-7.37 (m, 1H), 7.23-7.13 (m, 1H), 6.88 (s,1H), 5.94 (s, 1H), 3.82-3.71 (m, 4H), 3.46-3.41(m, 4H).::US10172859, Example 337::US11065253, Example 337::US9732094, Example 337	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315913&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106839	383542583							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659937	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1n[nH]c(=O)c2sccc12			315914	4-[[4-Fluoro-3-(7- morpholino- quinazolin-4-yl)- phenyl]hydroxy- methyl]-6H- thieno[2,3-d}- pyridazin-7-one1H NMR (500 MHz, DMSO-d6) ppm = 12.82 (s,1H), 9.09 (s, 1H), 8.18 (d, J = 5.2, 1H), 7.70-7.64(m, 2H), 7.62 (d, J = 5.2, 1H), 7.50 (dd, J = 9.4, 2.4,1H), 7.47 (dd, J = 9.4, 2.8, 1H), 7.44-7.36 (m, 1H),7.19 (d, J = 2.3, 1H), 6.62 (s, 1H), 6.01 (s, 1H),3.81-3.73 (m, 4H), 3.48-3.40 (m, 4H).::US10172859, Example 338::US11065253, Example 338::US9732094, Example 338	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315914&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106840	383542584							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659939	Cc1cc(C(O)c2cc(c(F)cc2Cl)-c2ncnc3cc(ccc23)N2CCOCC2)n(C)c(=O)c1	InChI=1S/C26H24ClFN4O3/c1-15-9-23(31(2)24(33)10-15)26(34)18-12-19(21(28)13-20(18)27)25-17-4-3-16(11-22(17)29-14-30-25)32-5-7-35-8-6-32/h3-4,9-14,26,34H,5-8H2,1-2H3	IASHPBTWDNSSJF-UHFFFAOYSA-N	315915	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1,4-dimethyl- 1H-pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s,1H), 7.79 (d, J = 9.5, 1H), 7.71 (d, J = 7.6, 1H), 7.60(dd, J = 9.4, 3.2, 1H), 7.54 (dd, J = 9.4, 2.5, 1H),7.22 (d, J = 2.4, 1H), 6.60 (d, J = 6.2, 1H), 6.27-6.15 (m, 1H), 6.05 (d, J = 6.2, 1H), 5.84-5.68 (m,1H), 3.81-3.75 (m, 4H), 3.52-3.43 (m, 7H),2.05 (s, 3H).::US10172859, Example 339::US11065253, Example 339::US9732094, Example 339	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315915&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954827	383542585							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659941	Cc1cc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)n(C)c(=O)c1	InChI=1S/C26H25FN4O3/c1-16-11-23(30(2)24(32)12-16)26(33)17-3-6-21(27)20(13-17)25-19-5-4-18(14-22(19)28-15-29-25)31-7-9-34-10-8-31/h3-6,11-15,26,33H,7-10H2,1-2H3	DGNYGAHGPZJGOK-UHFFFAOYSA-N	315916	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1,4-dimethyl- 1H-pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.62-7.54 (m, 2H), 7.54-7.49 (m, 2H),7.49-7.41 (m, 1H), 7.22-7.18 (m, 1H), 6.50 (d,J = 5.1, 1H), 6.21-6.15 (m, 2H), 5.90 (d, J = 5.1,1H), 3.81-3.74 (m, 4H), 3.48-3.41 (m, 4H),3.30 (s, 3H), 2.12 (s, 3H).::US10172859, Example 340::US11065253, Example 340::US9732094, Example 340	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315916	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315916&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954842	383542586							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659943	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12	InChI=1S/C25H19F2N5O2S/c26-19-11-20(27)18(25(33)24-16-3-8-35-22(16)12-30-31-24)10-17(19)23-15-2-1-14(9-21(15)28-13-29-23)32-4-6-34-7-5-32/h1-3,8-13,25,33H,4-7H2	CVCJPOLDSCPNQI-UHFFFAOYSA-N	315917	US10172859, Example 341::US11065253, Example 341::US9732094, Example 341::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.85 (d,J = 0.8, 1H), 9.12 (s, 1H), 8.33 (d, J = 5.3, 1H), 8.01(t, J = 8.1, 1H), 7.91 (dd, J = 5.4, 0.8, 1H), 7.66-7.50 (m, 2H), 7.43 (t, J = 10.1, 1H), 7.21 (d, J = 2.4,1H), 6.84 (s, 1H), 6.63 (s, 1H), 3.86-3.70 (m,4H), 3.54-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315917&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954803	383542587							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659945	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccsc12	InChI=1S/C25H19F2N5O2S/c26-19-11-20(27)18(24(33)23-25-14(3-8-35-25)12-30-31-23)10-17(19)22-16-2-1-15(9-21(16)28-13-29-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	DLKBPTITOLEWFS-UHFFFAOYSA-N	315918	US10172859, Example 342::US11065253, Example 342::US9732094, Example 342::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.57 (s,1H), 9.09 (s, 1H), 8.27 (d, J = 5.4, 1H), 7.86 (t,J = 8.0, 1H), 7.71 (d, J = 5.4, 1H), 7.61-7.42 (m,3H), 7.19 (d, J = 2.4, 1H), 7.16 (d, J = 4.8, 1H), 6.54(d, J = 4.8, 1H), 3.85-3.69 (m, 4H), 3.50-3.38 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315918	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315918&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954739	383542588							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659947	OC(c1nnc2ccccn12)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21FN6O2/c26-20-7-4-16(24(33)25-30-29-22-3-1-2-8-32(22)25)13-19(20)23-18-6-5-17(14-21(18)27-15-28-23)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	WKLHRHOHIWMJCS-UHFFFAOYSA-N	315919	US10172859, Example 343::US10172859, Example 344::US10172859, Example 399::US11065253, Example 399::US9732094, Example 399::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954839	383542589							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659949	OC(c1nnc2ccccn12)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21FN6O2/c26-20-7-4-16(24(33)25-30-29-22-3-1-2-8-32(22)25)13-19(20)23-18-6-5-17(14-21(18)27-15-28-23)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	WKLHRHOHIWMJCS-UHFFFAOYSA-N	315919	US10172859, Example 343::US10172859, Example 344::US10172859, Example 399::US11065253, Example 399::US9732094, Example 399::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954839	383542589							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659951	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C25H21FN6O2/c26-20-6-3-16(25(33)24-22-2-1-7-32(22)30-15-29-24)12-19(20)23-18-5-4-17(13-21(18)27-14-28-23)31-8-10-34-11-9-31/h1-7,12-15,25,33H,8-11H2	GHAFGFMIKAKPNE-UHFFFAOYSA-N	315921	US10172859, Example 345::US11065253, Example 345::US9732094, Example 345::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[2,1-f]- [1,2,4]triazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.49 (s, 1H), 8.08 (dd, J = 2.6, 1.4, 1H), 7.84-7.76 (m, 2H), 7.53-7.45 (m, 2H), 7.42-7.36 (m,1H), 7.29 (dd, J = 4.6, 1.4, 1H), 7.19 (d, J = 2.0, 1H),7.02 (dd, J = 4.6, 2.6, 1H), 6.62 (s, 1H), 6.07 (s,1H), 3.80-3.74 (m, 4H), 3.46-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315921&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954857	383542590							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659953	Cn1cnc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-13-32-23-22(30-12-31-25(23)33)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	YUNSFHVJJPXAJL-UHFFFAOYSA-N	315922	US10172859, Example 346::US10172859, Example 347::US10172859, Example 421::US11065253, Example 421::US9732094, Example 421::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954880	383542591							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659955	Cn1cnc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-13-32-23-22(30-12-31-25(23)33)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	YUNSFHVJJPXAJL-UHFFFAOYSA-N	315922	US10172859, Example 346::US10172859, Example 347::US10172859, Example 421::US11065253, Example 421::US9732094, Example 421::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954880	383542591							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659957	NC(=O)C(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C27H22F2N6O2/c28-20-14-21(29)19(13-18(20)24(27(30)36)26-23-2-1-6-35(23)7-5-31-26)25-17-4-3-16(12-22(17)32-15-33-25)34-8-10-37-11-9-34/h1-7,12-15,24H,8-11H2,(H2,30,36)	LUQVTTRAGKZSBB-UHFFFAOYSA-N	335818	2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyrrolo- [1,2-a]pyrazin-1-yl- acetamide::US11065253, Example 348::US9732094, Example 348	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335818&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117711818	384987975							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659959	Cc1nccnc1Cc1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O/c1-16-22(27-7-6-26-16)13-17-2-5-21(25)20(12-17)24-19-4-3-18(14-23(19)28-15-29-24)30-8-10-31-11-9-30/h2-7,12,14-15H,8-11,13H2,1H3	KRHAYZCIDMXCEA-UHFFFAOYSA-N	315925	4-[2-Fluoro-5-(3- methyl-pyrazin-2- ylmethyl)phenyl]-7- morpholin-4-yl- quinazoline1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.43-8.36 (m, 2H), 7.56-7.49 (m, 2H),7.46 (dd, J = 7.8, 5.5, 2H), 7.39-7.33 (m, 1H),7.22-7.16 (m, 1H), 4.28 (s, 2H), 3.81-3.75 (m,4H), 3.46-3.41 (m, 4H), 2.53 (s, 3H).::US10172859, Example 349::US11065253, Example 349::US9732094, Example 349	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315925&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954794	383542593							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659961	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccc2nncn12	InChI=1S/C25H20F2N6O2/c26-19-12-20(27)18(25(34)22-2-1-3-23-31-30-14-33(22)23)11-17(19)24-16-5-4-15(10-21(16)28-13-29-24)32-6-8-35-9-7-32/h1-5,10-14,25,34H,6-9H2	FTUHFJIZLOZDGE-UHFFFAOYSA-N	315926	US10172859, Example 350::US9732094, Example 350::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.33 (s,1H), 9.13 (s, 1H), 7.94 (t, J = 8.1, 1H), 7.80 (d,J = 9.2, 1H), 7.61-7.50 (m, 3H), 7.42 (dd, J = 9.26.8, 1H), 7.22 (d, J = 2.4, 1H), 6.93 (d, J = 5.7, 1H),6.87 (d, J = 6.8, 1H), 6.49 (d, J = 5.6, 1H), 3.83-3.75 (m, 4H), 3.49-3.43 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315926&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954754	383542594							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659963	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cnnc12	InChI=1S/C24H20FN7O2/c25-19-4-1-15(23(33)22-24-30-29-14-32(24)6-5-26-22)11-18(19)21-17-3-2-16(12-20(17)27-13-28-21)31-7-9-34-10-8-31/h1-6,11-14,23,33H,7-10H2	LNWVZTZLLMULBA-UHFFFAOYSA-N	315927	US10172859, Example 351::US11065253, Example 351::US9732094, Example 351::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]- pyrazin-8-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.44 (s,1H), 9.09 (s, 1H), 8.52 (d, J = 4.7, 1H), 7.91 (d,J = 4.7, 1H), 7.85-7.78 (m, 2H), 7.53 (dd, J = 9.4,2.9, 1H), 7.50 (dd, J = 9.4, 2.4 1H), 7.41-7.35 (m,1H), 7.20 (d, J = 2.3, 1H), 6.51 (s, 1H), 6.43 (s,1H), 3.82-3.74 (m, 4H), 3.47-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315927&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954874	383542595							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659965	COC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C	InChI=1S/C25H24FN5O2/c1-16-23(28-8-7-27-16)25(32-2)17-3-6-21(26)20(13-17)24-19-5-4-18(14-22(19)29-15-30-24)31-9-11-33-12-10-31/h3-8,13-15,25H,9-12H2,1-2H3	VJZQQSPYGNVLNF-UHFFFAOYSA-N	315928	4-{2-Fluoro-5- [methoxy-(3-methyl- pyrazin-2-yl)methyl]- phenyl}-7-morpholin- 4-ylquinazoline (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.53-8.42 (m, 2H), 7.69-7.58 (m, 2H),7.58-7.48 (m, 2H), 7.48-7.38 (m, 1H), 7.21 (d,J = 1.9, 1H), 5.80 (s, 1H), 3.81-3.70 (m, 4H), 3.48-3.39 (m, 4H), 3.36 (s, 3H), 2.59 (s, 3H).::US10172859, Example 352::US10172859, Example 353::US11065253, Example 353::US9732094, Example 353	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954815	383542596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659967	COC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C	InChI=1S/C25H24FN5O2/c1-16-23(28-8-7-27-16)25(32-2)17-3-6-21(26)20(13-17)24-19-5-4-18(14-22(19)29-15-30-24)31-9-11-33-12-10-31/h3-8,13-15,25H,9-12H2,1-2H3	VJZQQSPYGNVLNF-UHFFFAOYSA-N	315928	4-{2-Fluoro-5- [methoxy-(3-methyl- pyrazin-2-yl)methyl]- phenyl}-7-morpholin- 4-ylquinazoline (Ena 1)1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.53-8.42 (m, 2H), 7.69-7.58 (m, 2H),7.58-7.48 (m, 2H), 7.48-7.38 (m, 1H), 7.21 (d,J = 1.9, 1H), 5.80 (s, 1H), 3.81-3.70 (m, 4H), 3.48-3.39 (m, 4H), 3.36 (s, 3H), 2.59 (s, 3H).::US10172859, Example 352::US10172859, Example 353::US11065253, Example 353::US9732094, Example 353	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315928&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954815	383542596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659969	Cc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C25H24FN5O2/c1-15-13-27-23(16(2)30-15)25(32)17-3-6-21(26)20(11-17)24-19-5-4-18(12-22(19)28-14-29-24)31-7-9-33-10-8-31/h3-6,11-14,25,32H,7-10H2,1-2H3	PCLBXBKEXTTXEW-UHFFFAOYSA-N	315930	(3,5-Dimethyl- pyrazin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.30 (s, 1H), 7.60-7.50 (m, 4H), 7.41-7.33(m, 1H), 7.23-7.17 (m, 1H), 6.20 (d, J = 5.4, 1H),6.04 (d, J = 5.2, 1H), 3.81-3.76 (m, 4H), 3.47-3.42 (m, 4H), 2.50 (s, 3H), 2.43 (s, 3H).::US10172859, Example 354::US11065253, Example 354::US9732094, Example 354	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315930&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954915	383542597							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659971	Cc1cnc(C(O)c2cc(c(F)cc2F)-c2ncnc3cc(ccc23)N2CCOCC2)c(C)n1	InChI=1S/C25H23F2N5O2/c1-14-12-28-23(15(2)31-14)25(33)19-10-18(20(26)11-21(19)27)24-17-4-3-16(9-22(17)29-13-30-24)32-5-7-34-8-6-32/h3-4,9-13,25,33H,5-8H2,1-2H3	IPICVMLCQXXLCH-UHFFFAOYSA-N	315931	US10172859, Example 355::US11065253, Example 355::US9732094, Example 355::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3,5- dimethyl-pyrazin-2- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 8.26 (s, 1H), 7.89 (t, J = 8.2, 1H), 7.61 (dd,J = 9.4, 3.2, 1H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.39 (t,J = 10.1, 1H), 7.21 (d, J = 2.4, 1H), 6.28 (d, J = 6.0,1H), 6.23 (d, J = 6.0, 1H), 3.82-3.75 (m, 4H), 3.49-3.41 (m, 4H), 2.62 (s, 3H), 2.43 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315931&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954871	383542598							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659973	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H22FN5O2/c27-21-6-3-17(26(33)25-23-2-1-8-32(23)9-7-28-25)14-20(21)24-19-5-4-18(15-22(19)29-16-30-24)31-10-12-34-13-11-31/h1-9,14-16,26,33H,10-13H2	KEDFGJHVFDJAQW-UHFFFAOYSA-N	315932	US10172859, Example 356::US11065253, Example 356::US9732094, Example 356::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.20 (dd, J = 4.8, 1.0, 1H), 7.79-7.72 (m, 3H),7.53-7.45 (m, 3H), 7.40-7.34 (m, 1H), 7.20 (d,J = 2.1, 1H), 7.02 (dt, J = 4.1, 1.2, 1H), 6.87 (dd,J = 4.1, 2.5, 1H), 6.33 (d, J = 4.9, 1H), 6.06 (d,J = 4.8, 1H), 3.82-3.76 (m, 4H), 3.48-3.42 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315932&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954956	383542599							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659975	COc1ccc(nn1)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	VIBCJCNFUWTJBS-UHFFFAOYSA-N	315933	US10172859, Example 357::US11065253, Example 357::US9732094, Example 357::[2-Fluoro-4-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.00 (d, J = 7.1, 2.3, 1H), 7.89 (d, J = 9.4, 1H),7.80-7.71 (m, 2H), 7.55 (dd, J = 9.5, 2.6, 1H),7.38 (dd, J = 10.0, 8.4, 1H), 7.27-7.18 (m, 2H),6.57 (d, J = 4.8, 1H), 6.24 (d, J = 4.8, 1H), 4.01 (s,3H), 3.85-3.71 (m, 4H), 3.51-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315933&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954965	383542600							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659977	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H21F2N5O2/c27-20-14-21(28)19(26(34)25-23-2-1-6-33(23)7-5-29-25)13-18(20)24-17-4-3-16(12-22(17)30-15-31-24)32-8-10-35-11-9-32/h1-7,12-15,26,34H,8-11H2	WWULIMQUQVVHHC-UHFFFAOYSA-N	315934	US10172859, Example 358::US11065253, Example 358::US9732094, Example 358::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a] pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 8.25-8.19 (m, 1H), 7.94 (t, J = 8.2, 1H), 7.78(dd, J = 2.5, 1.3, 1H), 7.58 (dd, J = 9.3, 3.0, 1H),7.55 (dd, J = 9.4, 2.4, 1H), 7.47-7.39 (m, 2H),7.22 (d, J = 2.3, 1H), 6.97-6.93 (m, 1H), 6.91 (dd,J = 4.1, 2.5, 1H), 6.43 (d, J = 5.9, 1H), 6.30 (d,J = 5.9, 1H), 3.82-3.76 (m, 4H), 3.49-3.44 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315934&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954760	383542601							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659979	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H21ClFN5O2/c27-20-14-21(28)19(13-18(20)26(34)25-23-2-1-6-33(23)7-5-29-25)24-17-4-3-16(12-22(17)30-15-31-24)32-8-10-35-11-9-32/h1-7,12-15,26,34H,8-11H2	OWORGYHATQJZBK-UHFFFAOYSA-N	315935	US10172859, Example 359::US11065253, Example 359::US9732094, Example 359::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.12 (s,1H), 8.20 (dd, J = 4.7, 1.0, 1H), 7.97 (d, J = 7.8, 1H),7.76 (dd, J = 2.5, 1.3, 1H), 7.63 (d, J = 9.5, 1H), 7.60(dd, J = 9.4, 3.2, 1H), 7.55 (dd, J = 9.4, 2.6, 1H),7.40 (d, J = 4.8, 1H), 7.21 (d, J = 2.5, 1H), 7.00-6.95 (m, 1H), 6.91 (dd, J = 4.1, 2.5, 1H), 6.48 (d,J = 6.2, 1H), 6.36 (d, J = 6.1, 1H), 3.81-3.75 (m,4H), 3.48-3.43 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315935&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954837	383542602							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659981	Cn1c(nccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-29-21(31)6-7-26-24(29)23(32)15-2-5-19(25)18(12-15)22-17-4-3-16(13-20(17)27-14-28-22)30-8-10-33-11-9-30/h2-7,12-14,23,32H,8-11H2,1H3	VRBINPYXVFOIEZ-UHFFFAOYSA-N	315936	2-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-3-methyl-3H- pyrimidin-4-one1H NMR (400 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.91 (d, J = 6.5, 1H), 7.67-7.60 (m, 2H), 7.60-7.50 (m, 2H), 7.44 (t, J = 9.5, 1H), 7.20 (d, J = 1.7,1H), 6.72 (s, 1H), 6.38 (d, J = 6.5, 1H), 6.00 (s,1H), 3.82-3.73 (m, 4H), 3.48 (s, 3H), 3.47-3.42(m, 4H).::US10172859, Example 360::US11065253, Example 360::US9732094, Example 360	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315936&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954770	383542603							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659983	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12	InChI=1S/C26H22ClN5O2/c27-21-6-3-17(14-20(21)26(33)25-23-2-1-8-32(23)9-7-28-25)24-19-5-4-18(15-22(19)29-16-30-24)31-10-12-34-13-11-31/h1-9,14-16,26,33H,10-13H2	MAVRQQXHKQFAMV-UHFFFAOYSA-N	315937	US10172859, Example 361::US11065253, Example 361::US9732094, Example 361::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.22-8.19 (m, 1H), 8.14 (d, J = 2.2, 1H), 7.89(d, J = 9.4, 1H), 7.76 (dd, J = 2.5, 1.3, 1H), 7.70 (dd,J = 8.2, 2.2, 1H), 7.61 (d, J = 8.2, 1H), 7.53 (dd,J = 9.5, 2.6, 1H). 7.43 (d, J = 4.8, 1H), 7.21 (d,J = 2.6, 1H), 7.00-6.97 (m, 1H), 6.93-6.90 (m,1H), 6.45-6.40 (m, 2H), 3.81-3.76 (m, 4H),3.48-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315937&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954797	383542604							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659985	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnn2cccc12	InChI=1S/C25H21ClN6O2/c26-20-6-3-16(12-19(20)25(33)24-22-2-1-7-32(22)30-15-29-24)23-18-5-4-17(13-21(18)27-14-28-23)31-8-10-34-11-9-31/h1-7,12-15,25,33H,8-11H2	VHMBWFZHXLMGJM-UHFFFAOYSA-N	315938	US10172859, Example 362::US11065253, Example 362::US9732094, Example 362::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[2,1-f]- [1,2,4]triazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.49 (s, 1H), 8.16 (d, J = 2.2, 1H), 8.12 (dd,J = 2.6, 1.4, 1H), 7.88 (d, J = 9.4, 1H), 7.74 (dd,J = 8.2, 2.2, 1H), 7.64 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.23-7.19 (m, 2H), 7.06 (dd,J = 4.6, 2.6, 1H), 6.80 (d, J = 5.7, 1H), 6.44 (d,J = 5.7, 1H), 3.81-3.76 (m, 4H), 3.48-3.43 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315938&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954877	383542605							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659987	Cn1c(cccc1=O)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	NGKARPNDTRDPQL-UHFFFAOYSA-N	315939	6-{[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 363::US10172859, Example 364::US10172859, Example 400::US11065253, Example 400::US9732094, Example 400	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954744	383542606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659989	Cn1c(cccc1=O)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	NGKARPNDTRDPQL-UHFFFAOYSA-N	315939	6-{[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 363::US10172859, Example 364::US10172859, Example 400::US11065253, Example 400::US9732094, Example 400	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954744	383542606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659991	Cn1c(cccc1=O)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	PKBPQGNBNQFAKJ-UHFFFAOYSA-N	315941	6-{[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 365::US10172859, Example 366::US10172859, Example 401::US11065253, Example 401::US9732094, Example 401	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954788	383542607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659993	Cn1c(cccc1=O)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	PKBPQGNBNQFAKJ-UHFFFAOYSA-N	315941	6-{[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 365::US10172859, Example 366::US10172859, Example 401::US11065253, Example 401::US9732094, Example 401	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954788	383542607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659995	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ccc(=O)[nH]n1			315651	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- hydroxymethyl}-2H- pyridazin-3-one (Ena 2)1H NMR (400 MHz, DMSO-d6) ppm = 12.86 (s, 1H), 9.10 (s, 1H), 7.64-7.58 (m, 2H), 7.55-7.50 (m, 2H), 7.48 (d, J = 9.8, 1H), 7.45-7.38 (m, 1H), 7.23-7.16 (m, 1H), 6.87 (d, J = 9.8, 1H), 6.44 (d, J = 4.3, 1H), 5.70-5.62 (m, 1H), 3.81-3.74 (m, 4H), 3.47-3.41 (m, 4H)::US10172859, Example 367::US10172859, Example 76::US11065253, Example 76::US9732094, Example 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315651&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138106837	383542390							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659997	Cn1c(nccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-30-21(32)4-5-27-24(30)23(33)16-11-17(19(26)12-18(16)25)22-15-3-2-14(10-20(15)28-13-29-22)31-6-8-34-9-7-31/h2-5,10-13,23,33H,6-9H2,1H3	SVHBTMUPWLWKHQ-UHFFFAOYSA-N	315944	2-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-3-methyl-3H- pyrimidin-4-one1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 7.88 (d, J = 7.7, 1H), 7.83 (d, J = 6.5, 1H), 7.70(d, J = 9.4, 1H), 7.63 (dd, J = 9.4, 3.2, 1H), 7.57 (dd,J = 9.5, 2.5, 1H), 7.23 (d, J = 2.4, 1H), 6.91 (d,J = 7.0, 1H), 6.39 (d, J = 6.5, 1H), 6.15 (d, J = 7.0,1H), 3.83-3.76 (m, 4H), 3.72 (s, 3H), 3.50-3.44(m, 4H).::US10172859, Example 368::US11065253, Example 368::US9732094, Example 368	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315944&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954793	383542608							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
659999	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H21ClN6O2/c26-20-4-1-16(13-19(20)24(33)23-25-28-6-8-32(25)7-5-27-23)22-18-3-2-17(14-21(18)29-15-30-22)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	STWNBZFJDDCWDB-UHFFFAOYSA-N	315945	US10172859, Example 369::US11065253, Example 369::US9732094, Example 369::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.57 (d, J = 4.5, 1H), 8.27 (d, J = 2.2, 1H), 8.18(d, J = 1.1, 1H), 8.04 (d, J = 9.4, 1H), 7.88 (d, J = 1.1,1H), 7.83 (d, J = 4.5, 1H), 7.72 (dd, J = 8.2, 2.3, 1H),7.62-7.55 (m, 2H), 7.23 (d, J = 2.6, 1H), 6.87 (d,J = 5.8, 1H), 6.50 (d, J = 5.9, 1H), 3.83-3.78 (m,4H), 3.50-3.45 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315945&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954933	383542609							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660001	Cn1cnc2c(ncnc12)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-14-31-23-22(29-13-30-25(23)32)24(34)18-10-15(2-5-19(18)26)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	TVNNXSNDWDOGSD-UHFFFAOYSA-N	315946	US10172859, Example 370::US11065253, Example 370::US9732094, Example 370::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.91 (s, 1H), 8.58 (s, 1H), 8.28 (dd, J = 7.0,2.3, 1H), 8.05 (d, J = 9.4, 1H), 7.72 (ddd, J = 8.3,5.0, 2.4, 1H), 7.58 (dd, J = 9.5, 2.6, 1H), 7.30 (dd,J = 10.0, 8.5, 1H), 7.21 (d, J = 2.5, 1H), 6.66 (d,J = 5.5, 1H), 6.44 (d, J = 5.6, 1H), 3.85 (s, 3H), 3.82-3.78 (m, 4H), 3.49-3.45 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315946&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954833	383542610							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660003	Cn1cnc2c(ncnc12)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClN7O2/c1-32-14-31-23-22(29-13-30-25(23)32)24(34)18-10-15(2-5-19(18)26)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	SLTAVZNCQZTPAE-UHFFFAOYSA-N	315947	US10172859, Example 371::US11065253, Example 371::US9732094, Example 371::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.90 (s, 1H), 8.59 (s, 1H), 8.38 (d, J = 2.2,1H), 8.12 (d, J = 9.4, 1H), 7.70 (dd, J = 8.8, 2.3, 1H),7.60 (dd, J = 9.5, 2.6, 1H), 7.56 (d, J = 8.2, 1H), 7.23(d, J = 2.6, 1H), 6.71 (d, J = 5.4, 1H), 6.53 (d, J = 5.4,1H), 3.86 (s, 3H), 3.82-3.77 (m, 4H), 3.49-3.45(m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315947&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954955	383542611							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660005	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H21FN6O2/c26-20-4-1-16(13-19(20)24(33)23-25-28-6-8-32(25)7-5-27-23)22-18-3-2-17(14-21(18)29-15-30-22)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	SQAFIECUCNRFEB-UHFFFAOYSA-N	315948	US10172859, Example 372::US11065253, Example 372::US9732094, Example 372::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.58 (d, J = 4.5, 1H), 8.24-8.16 (m, 2H), 8.00(d, J = 9.4, 1H), 7.91-7.83 (m, 2H), 7.74 (ddd,J = 8.1, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6, 1H),7.33 (dd, J = 10.0, 8.5, 1H), 7.22 (d, J = 2.5, 1H),6.80 (d, J = 5.9, 1H), 6.39 (d, J = 6.0, 1H), 3.86-3.75 (m, 4H), 3.52-3.43 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315948&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954912	383542612							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660007	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1cccc2nncn12	InChI=1S/C25H21FN6O2/c26-20-7-4-16(12-19(20)25(33)22-2-1-3-23-30-29-15-32(22)23)24-18-6-5-17(13-21(18)27-14-28-24)31-8-10-34-11-9-31/h1-7,12-15,25,33H,8-11H2	GEQVWQSNVNSBLE-UHFFFAOYSA-N	315949	US10172859, Example 373::US11065253, Example 373::US9732094, Example 373::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.36-9.30(m, 1H), 9.07 (s, 1H), 8.03 (dd, J = 7.2, 2.3, 1H),7.86-7.76 (m, 3H), 7.52-7.38 (m, 3H), 7.21 (d,J = 2.6, 1H), 6.91 (d, J = 5.6, 1H), 6.87-6.80 (m,1H), 6.53 (d, J = 5.6, 1H), 3.83-3.74 (m, 4H), 3.48-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315949	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315949&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954924	383542613							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660009	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	AYUGGJOQLWWJHH-UHFFFAOYSA-N	315950	US10172859, Example 374::US11065253, Example 374::US9732094, Example 374::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 9.02 (s, 1H), 8.59 (d, J = 2.2, 1H), 8.20 (dd,J = 7.0, 2.3, 1H), 7.92 (d, J = 9.4, 1H), 7.77 (ddd,J = 8.4, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6, 1H),7.37 (dd, J = 10.0, 8.5, 1H), 7.27 (d, J = 2.3, 1H),7.22 (d, J = 2.5, 1H), 6.73 (d, J = 5.2, 1H), 6.48 (d,J = 5.1, 1H), 3.82-3.76 (m, 4H), 3.49-3.44 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315950	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315950&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954748	383542614							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660011	Cn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)16-5-8-20(26)19(13-16)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	IVAQITIIINVXDO-UHFFFAOYSA-N	315666	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.60-7.56 (m, 2H), 7.55-7.51 (m, 2H), 7.48- 7.43 (m, 1H), 7.40 (dd, J = 9.1, 6.9, 1H), 7.21-7.19 (m, 1H), 6.52 (d, J = 5.3, 1H), 6.36 (dd, J = 9.1, 1.4, 1H), 6.25 (dd, J = 7.0, 1.4, 1H), 5.94 (d, J = 5.1, 1H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.38 (s, 3H).::US10172859, Example 375::US10172859, Example 376::US10172859, Example 91::US11065253, Example 91::US9732094, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315666&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292653	383542404							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660013	Cn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)16-5-8-20(26)19(13-16)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	IVAQITIIINVXDO-UHFFFAOYSA-N	315666	6-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s, 1H), 7.60-7.56 (m, 2H), 7.55-7.51 (m, 2H), 7.48- 7.43 (m, 1H), 7.40 (dd, J = 9.1, 6.9, 1H), 7.21-7.19 (m, 1H), 6.52 (d, J = 5.3, 1H), 6.36 (dd, J = 9.1, 1.4, 1H), 6.25 (dd, J = 7.0, 1.4, 1H), 5.94 (d, J = 5.1, 1H), 3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H), 3.38 (s, 3H).::US10172859, Example 375::US10172859, Example 376::US10172859, Example 91::US11065253, Example 91::US9732094, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315666&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292653	383542404							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660015	Cc1cncnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-12-28-13-30-23(15)22(25(27)33)19-10-16(2-5-20(19)26)24-18-4-3-17(11-21(18)29-14-31-24)32-6-8-34-9-7-32/h2-5,10-14,22H,6-9H2,1H3,(H2,27,33)	XNDMXGNHPWCDKX-UHFFFAOYSA-N	315953	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(5-methyl- pyrimidin-4-yl)- acetamide (Ena 2)see racemate::US10172859, Example 377::US10172859, Example 378::US10172859, Example 407::US11065253, Example 407::US9732094, Example 407	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954832	383542615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660017	Cc1cncnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-12-28-13-30-23(15)22(25(27)33)19-10-16(2-5-20(19)26)24-18-4-3-17(11-21(18)29-14-31-24)32-6-8-34-9-7-32/h2-5,10-14,22H,6-9H2,1H3,(H2,27,33)	XNDMXGNHPWCDKX-UHFFFAOYSA-N	315953	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(5-methyl- pyrimidin-4-yl)- acetamide (Ena 2)see racemate::US10172859, Example 377::US10172859, Example 378::US10172859, Example 407::US11065253, Example 407::US9732094, Example 407	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954832	383542615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660019	OC(c1nnc2ccccn12)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H20F2N6O2/c26-19-13-20(27)18(24(34)25-31-30-22-3-1-2-6-33(22)25)12-17(19)23-16-5-4-15(11-21(16)28-14-29-23)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	KVBITJQMDOZXFN-UHFFFAOYSA-N	315956	US10172859, Example 379::US11065253, Example 379::US9732094, Example 379::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 8.63 (dt, J = 7.1, 1.2, 1H), 8.02 (t, J = 8.1, 1H),7.81 (dt, J = 9.3, 1.1, 1H), 7.64 (dd, J = 9.4, 3.3, 1H),7.60-7.50 (m, 2H), 7.44 (ddd, J = 9.3, 6.6, 1.1,1H), 7.23 (d, J = 2.5, 1H), 7.06 (td, J = 6.8, 1.0, 1H),6.87 (d, J = 6.0, 1H), 6.69 (d, J = 6.0, 1H), 3.82-3.77 (m, 4H), 3.49-3.45 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315956&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954740	383542617							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660021	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-30-22(3-2-4-23(30)32)25(33)18-12-17(19(26)13-20(18)27)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	TYEQLJVPHLCAPI-UHFFFAOYSA-N	315957	6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 380::US10172859, Example 381::US10172859, Example 436::US11065253, Example 436::US9732094, Example 436	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954779	383542618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660023	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-30-22(3-2-4-23(30)32)25(33)18-12-17(19(26)13-20(18)27)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	TYEQLJVPHLCAPI-UHFFFAOYSA-N	315957	6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 380::US10172859, Example 381::US10172859, Example 436::US11065253, Example 436::US9732094, Example 436	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954779	383542618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660025	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-30-22(3-2-4-23(30)32)25(33)17-12-18(20(27)13-19(17)26)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	WYNSFINJUTXESJ-UHFFFAOYSA-N	315959	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 382::US10172859, Example 383::US10172859, Example 435::US11065253, Example 435::US9732094, Example 435	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696425	383542619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660027	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-30-22(3-2-4-23(30)32)25(33)17-12-18(20(27)13-19(17)26)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	WYNSFINJUTXESJ-UHFFFAOYSA-N	315959	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 382::US10172859, Example 383::US10172859, Example 435::US11065253, Example 435::US9732094, Example 435	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696425	383542619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660029	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3F)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21F2N7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	VGKMJMNCNMRSEO-UHFFFAOYSA-N	315961	(R)-[2,4-Difluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 384::US10172859, Example 386::US10172859, Example 431::US11065253, Example 431::US9732094, Example 431	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954829	383542620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660031	Cn1ncc2c(ncnc12)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClN7O2/c1-32-25-19(12-31-32)23(29-14-30-25)24(34)18-10-15(2-5-20(18)26)22-17-4-3-16(11-21(17)27-13-28-22)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	BSOZSTWDPAKLPX-UHFFFAOYSA-N	315962	US10172859, Example 385::US9732094, Example 385::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.92 (s, 1H), 8.44 (s, 1H), 7.95 (d, J = 2.2,1H), 7.80 (d, J = 9.4, 1H), 7.72 (dd, J = 8.2, 2.2, 1H),7.66 (d, J = 8.2, 1H), 7.50 (dd, J = 9.5, 2.6, 1H), 7.19(d, J = 2.5, 1H), 6.90 (d, J = 4.9, 1H), 6.49 (d, J = 4.9,1H), 4.05 (s, 3H), 3.82-3.76 (m, 4H), 3.47-3.41(m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315962&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954866	383542621							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660033	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3F)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21F2N7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	VGKMJMNCNMRSEO-UHFFFAOYSA-N	315961	(R)-[2,4-Difluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 384::US10172859, Example 386::US10172859, Example 431::US11065253, Example 431::US9732094, Example 431	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954829	383542620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660035	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2CNCCc12	InChI=1S/C26H24F2N6O2/c27-20-11-21(28)19(26(35)25-17-3-4-29-12-23(17)31-14-33-25)10-18(20)24-16-2-1-15(9-22(16)30-13-32-24)34-5-7-36-8-6-34/h1-2,9-11,13-14,26,29,35H,3-8,12H2	DGNNVCHHZJSLTB-UHFFFAOYSA-N	315964	US10172859, Example 387::US9732094, Example 387::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5,6,7,8- tetrahydropyrido- [3,4-d}pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.83 (s, 1H), 7.87 (t, J = 8.2, 1H), 7.60 (dd,J = 9.4, 3.0, 1H), 7.56 (dd, J = 9.4, 2.5, 1H), 7.42 (t,J = 10.1, 1H), 7.21 (d, J = 2.4, 1H), 6.33 (d, J = 6.3,1H), 6.16 (d, J = 6.3, 1H), 3.86 (s, 2H), 3.82-3.75(m, 4H), 3.49-3.42 (m, 4H), 3.09-2.94 (m, 2H),2.94-2.72 (m, 2H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315964&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954790	383542622							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660037	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2CNCCc12	InChI=1S/C26H25FN6O2/c27-21-4-1-16(26(34)25-19-5-6-28-13-23(19)30-15-32-25)11-20(21)24-18-3-2-17(12-22(18)29-14-31-24)33-7-9-35-10-8-33/h1-4,11-12,14-15,26,28,34H,5-10,13H2	CCPJVMRJOCCOET-UHFFFAOYSA-N	315965	US10172859, Example 388::US9732094, Example 388::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5,6,7,8- tetrahydropyrido- [3,4-d}pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.88 (s, 1H), 7.64-7.56 (m, 2H), 7.55-7.50(m, 2H), 7.38 (dd, J = 10.5, 8.1, 1H), 7.23-7.16(m, 1H), 6.20 (d, J = 5.8, 1H), 5.96 (d, J = 5.8, 1H),3.83 (s, 2H), 3.81-3.72 (m, 4H), 3.49-3.39 (m,4H), 3.05-2.84 (m, 2H), 2.77-2.72 (m, 2H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315965&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966402	383542623							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660039	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncncc1F	InChI=1S/C23H19ClFN5O2/c24-18-4-1-14(9-17(18)23(31)22-19(25)11-26-12-28-22)21-16-3-2-15(10-20(16)27-13-29-21)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	LGZAMQCFFYGHBM-UHFFFAOYSA-N	315966	US10172859, Example 389::US10172859, Example 390::US10172859, Example 412::US11065253, Example 412::US9732094, Example 412::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-fluoro- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954820	383542624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660041	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncncc1F	InChI=1S/C23H19ClFN5O2/c24-18-4-1-14(9-17(18)23(31)22-19(25)11-26-12-28-22)21-16-3-2-15(10-20(16)27-13-29-21)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	LGZAMQCFFYGHBM-UHFFFAOYSA-N	315966	US10172859, Example 389::US10172859, Example 390::US10172859, Example 412::US11065253, Example 412::US9732094, Example 412::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-fluoro- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954820	383542624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660043	Cn1ncc2c(ncnc12)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-25-19(12-31-32)23(29-14-30-25)24(34)18-10-15(2-5-20(18)26)22-17-4-3-16(11-21(17)27-13-28-22)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	HTZLXCWYVJYAAH-UHFFFAOYSA-N	315968	US10172859, Example 391::US11065253, Example 391::US9732094, Example 391::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.05 (s,1H), 8.90 (s, 1H), 8.49 (s, 1H), 7.93 (dd, J = 6.9,2.3, 1H), 7.81 (d, J = 9.4, 1H), 7.74 (ddd, J = 8.4,4.9, 2.3, 1H), 7.52 (dd, J = 9.5, 2.6, 1H), 7.40 (dd,J = 9.9, 8.5, 1H), 7.19 (d, J = 2.6, 1H), 6.88 (s, 1H),6.37 (s, 1H), 4.05 (s, 3H), 3.81-3.75 (m, 4H),3.51-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954845	383542625							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660045	Cc1cncnc1C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	JJQXPFGHPBRZAM-UHFFFAOYSA-N	315969	US10172859, Example 392::US11065253, Example 392::US9732094, Example 392::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.98 (s, 1H), 8.64 (s, 1H), 8.07 (dd, J = 7.1,2.3, 1H), 7.93 (d, J = 9.4, 1H), 7.74 (ddd, J = 8.3,5.0, 2.3, 1H), 7.57 (dd, J = 9.5, 2.6 1H), 7.35 (dd,J = 10.1, 8.4, 1H), 7.21 (d, J = 2.6, 1H), 6.38 (d,J = 6.0 1H), 6.25 (d, J = 6.0, 1H), 3.82-3.76 (m,4H), 3.51-3.43 (m, 4H), 2.41 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315969&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955005	383542626							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660047	Cc1nccnc1C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QBVSEWPWWHRRDD-UHFFFAOYSA-N	315970	US10172859, Example 393::US11065253, Example 393::US9732094, Example 393::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.45 (d, J = 2.5, 1H), 8.41 (d, J = 2.5, 1H), 8.09(dd, J = 7.1, 2.3, 1H), 7.94 (d, J = 9.4, 1H), 7.74(ddd, J = 7.9, 5.0, 2.3, 1H), 7.56 (dd, J = 9.5, 2.6,1H), 7.33 (dd, J = 10.1, 8.4, 1H), 7.21 (d, J = 2.5,1H), 6.35 (d, J = 5.8, 1H), 6.32 (d, J = 5.9, 1H), 3.83-3.76 (m, 4H), 3.45 (t, J = 4.9, 4H), 2.68 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315970&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954934	383542627							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660049	COc1nccnc1C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22FN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QDHRMZSLIZGZJU-UHFFFAOYSA-N	315971	US10172859, Example 394::US11065253, Example 394::US9732094, Example 394::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.19 (d, J = 2.7, 1H), 8.17 (d, J = 2.7, 1H), 8.07(dd, J = 8.3, 1H), 7.93 (d, J = 9.4, 1H), 7.73(ddd, J = 8.3, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6,1H), 7.33 (dd, J = 10.1, 8.4, 1H), 7.22 (d, J = 2.5,1H), 6.35 (d, J = 6.0, 1H), 6.21 (d, J = 6.0, 1H), 3.98(s, 3H), 3.82-3.76 (m, 4H), 3.46 (dd, J = 5.9, 3.9,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315971&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954851	383542628							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660051	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)24(34)23-25-29-4-6-33(25)5-3-28-23)22-16-2-1-15(11-21(16)30-14-31-22)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	SRSGLQYXZLUTFB-UHFFFAOYSA-N	315972	US10172859, Example 395::US10172859, Example 396::US10172859, Example 397::US11065253, Example 397::US9732094, Example 397::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954861	383542629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660053	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)24(34)23-25-29-4-6-33(25)5-3-28-23)22-16-2-1-15(11-21(16)30-14-31-22)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	SRSGLQYXZLUTFB-UHFFFAOYSA-N	315972	US10172859, Example 395::US10172859, Example 396::US10172859, Example 397::US11065253, Example 397::US9732094, Example 397::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954861	383542629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660055	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2ccnc12	InChI=1S/C25H20ClFN6O2/c26-19-13-20(27)18(12-17(19)24(34)23-25-29-4-6-33(25)5-3-28-23)22-16-2-1-15(11-21(16)30-14-31-22)32-7-9-35-10-8-32/h1-6,11-14,24,34H,7-10H2	SRSGLQYXZLUTFB-UHFFFAOYSA-N	315972	US10172859, Example 395::US10172859, Example 396::US10172859, Example 397::US11065253, Example 397::US9732094, Example 397::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [1,2-a]pyrazin-8-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954861	383542629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660057	CCn1c(cccc1=O)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H25FN4O3/c1-2-31-23(4-3-5-24(31)32)26(33)17-6-9-21(27)20(14-17)25-19-8-7-18(15-22(19)28-16-29-25)30-10-12-34-13-11-30/h3-9,14-16,26,33H,2,10-13H2,1H3	HPNZHZQMNZAMPI-UHFFFAOYSA-N	315975	1-Ethyl-6-{[4-fluoro- 3-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1H-pyridin-2- one1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 7.63-7.56 (m, 2H), 7.54 (dd, J = 9.4, 2.5, 1H),7.52-7.43 (m, 2H), 7.41 (dd, J = 9.1, 6.9, 1H),7.20 (d, J = 2.4, 1H), 6.58 (d, J = 1H), 6.35 (dd,J = 9.1, 1.4, 1H), 6.31 (dd, J = 7.1, 1.4, 1H), 5.91 (d,J = 5.0, 1H), 4.05-3.88 (m, 2H), 3.81-3.74 (m,4H), 3.48-3.39 (m, 4H), 0.95 (t, J = 6.9, 3H).::US10172859, Example 398::US11065253, Example 398::US9732094, Example 398	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315975&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966403	383542630							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660059	OC(c1nnc2ccccn12)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21FN6O2/c26-20-7-4-16(24(33)25-30-29-22-3-1-2-8-32(22)25)13-19(20)23-18-6-5-17(14-21(18)27-15-28-23)31-9-11-34-12-10-31/h1-8,13-15,24,33H,9-12H2	WKLHRHOHIWMJCS-UHFFFAOYSA-N	315919	US10172859, Example 343::US10172859, Example 344::US10172859, Example 399::US11065253, Example 399::US9732094, Example 399::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-[1,2,4]- triazolo[4,3-a]pyridin- 3-ylmethanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315919&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954839	383542589							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660061	Cn1c(cccc1=O)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	NGKARPNDTRDPQL-UHFFFAOYSA-N	315939	6-{[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 363::US10172859, Example 364::US10172859, Example 400::US11065253, Example 400::US9732094, Example 400	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315939&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954744	383542606							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660063	Cn1c(cccc1=O)C(O)c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O3/c1-29-22(3-2-4-23(29)31)25(32)19-13-16(5-8-20(19)26)24-18-7-6-17(14-21(18)27-15-28-24)30-9-11-33-12-10-30/h2-8,13-15,25,32H,9-12H2,1H3	PKBPQGNBNQFAKJ-UHFFFAOYSA-N	315941	6-{[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 365::US10172859, Example 366::US10172859, Example 401::US11065253, Example 401::US9732094, Example 401	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315941&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954788	383542607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660065	Cn1ncc2c(ncnc12)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21ClFN7O2/c1-33-25-18(11-32-33)23(30-13-31-25)24(35)16-9-17(20(27)10-19(16)26)22-15-3-2-14(8-21(15)28-12-29-22)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	BQKWVPQKBYQALO-UHFFFAOYSA-N	315979	US10172859, Example 402::US11065253, Example 402::US9732094, Example 402::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d]- pyrimdiin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.90 (s, 1H), 8.44 (s, 1H), 7.81 (d, J = 7.6,1H), 7.69 (d, J = 9.5, 1H), 7.56-7.48 (m, 2H), 7.22-7.16 (m, 1H), 6.92 (d, J = 5.0, 1H), 6.43 (d, J = 5.0,1H), 4.04 (s, 3H), 3.81-3.74 (m, 4H), 3.48-3.40(m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315979&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954753	383542631							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660067	Cn1ncc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-25-18(11-32-33)23(30-13-31-25)24(35)17-9-16(19(26)10-20(17)27)22-15-3-2-14(8-21(15)28-12-29-22)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	IGGXDPOYOQKHHJ-UHFFFAOYSA-N	315980	US10172859, Example 403::US11065253, Example 403::US9732094, Example 403::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.89 (s, 1H), 8.49 (s, 1H), 7.79 (t, J = 8.0,1H), 7.56-7.50 (m, 2H), 7.47 (t, J = 10.0, 1H),7.19 (s, 1H), 6.88 (s, 1H), 6.32 (s, 1H), 4.04 (s,3H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315980&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954928	383542632							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660069	Cn1ncc2c(ncnc12)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-25-19(12-31-32)23(29-14-30-25)24(34)15-2-5-20(26)18(10-15)22-17-4-3-16(11-21(17)27-13-28-22)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	HPWPZDRXPQVODT-UHFFFAOYSA-N	315981	US10172859, Example 404::US11065253, Example 404::US9732094, Example 404::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(1-methyl- 1H-pyrazolo[3,4-d}- pyrimidin-4-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.91 (s, 1H), 8.53 (s, 1H), 7.79-7.72 (m,2H), 7.54-7.44 (m, 2H), 7.38 (dd, J = 9.8, 8.4, 1H),7.19 (d, J = 2.1, 1H), 6.79 (d, J = 4.0, 1H), 6.10 (d,J = 3.3, 1H), 4.03 (s, 3H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315981&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954741	383542633							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660071	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H20FN5O2S/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-10-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	BKVDUGPHOXFCIL-UHFFFAOYSA-N	315982	US10172859, Example 405::US11065253, Example 405::US9732094, Example 405::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 9.04 (s, 1H), 8.49 (d, J = 5.5, 1H), 7.91 (dd,J = 6.9, 2.3, 1H), 7.80 (d, J = 9.4, 1H), 7.79-7.74(m, 1H), 7.63 (d, J = 5.5, 1H), 7.49 (dd, J = 9.5, 2.6,1H), 7.43 (dd, J = 9.9, 8.5, 1H), 7.21-7.15 (m, 2H),6.38 (d, J = 2.1, 1H), 3.83-3.76 (m, 4H), 3.47-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315982	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315982&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954755	383542634							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660073	OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(11-19(20)24(32)23-18-5-10-34-25(18)30-14-29-23)22-17-3-2-16(12-21(17)27-13-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	VAZNQKKOJUYTLR-UHFFFAOYSA-N	315983	US10172859, Example 406::US11065253, Example 406::US9732094, Example 406::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 9.03 (s, 1H), 8.48 (d, J = 5.6, 1H), 7.90 (dd,J = 6.9, 2.3, 1H), 7.79 (d, J = 9.4, 1H), 7.78-7.73(m, 1H), 7.62 (d, J = 5.6, 1H), 7.48 (dd, J = 9.5, 2.6,1H), 7.41 (dd, J = 9.9, 8.5, 1H), 7.18 (d, J = 2.6, 1H),7.16 (d, J = 4.7, 1H), 6.36 (d, J = 4.5, 1H), 3.82-3.74 (m, 4H), 3.48-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315983&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966404	383542635							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660075	Cc1cncnc1C(C(N)=O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23ClN6O2/c1-15-12-28-13-30-23(15)22(25(27)33)19-10-16(2-5-20(19)26)24-18-4-3-17(11-21(18)29-14-31-24)32-6-8-34-9-7-32/h2-5,10-14,22H,6-9H2,1H3,(H2,27,33)	XNDMXGNHPWCDKX-UHFFFAOYSA-N	315953	2-[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-(5-methyl- pyrimidin-4-yl)- acetamide (Ena 2)see racemate::US10172859, Example 377::US10172859, Example 378::US10172859, Example 407::US11065253, Example 407::US9732094, Example 407	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315953&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954832	383542615							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660077	COc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-21-12-26-13-28-23(21)24(31)18-10-15(2-5-19(18)25)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	OTIHBNMSAHVGDN-UHFFFAOYSA-N	315985	US10172859, Example 408::US10172859, Example 409::US10172859, Example 413::US11065253, Example 422::US9732094, Example 413::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954975	383542636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660079	COc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-21-12-26-13-28-23(21)24(31)18-10-15(2-5-19(18)25)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	OTIHBNMSAHVGDN-UHFFFAOYSA-N	315985	US10172859, Example 408::US10172859, Example 409::US10172859, Example 413::US11065253, Example 422::US9732094, Example 413::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954975	383542636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660081	COc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QZQZLQSAQQUISA-UHFFFAOYSA-N	315987	US10172859, Example 410::US10172859, Example 411::US10172859, Example 422::US11065253, Example 411::US9732094, Example 422::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954914	383542637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660083	COc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QZQZLQSAQQUISA-UHFFFAOYSA-N	315987	US10172859, Example 410::US10172859, Example 411::US10172859, Example 422::US11065253, Example 411::US9732094, Example 422::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954914	383542637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660085	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncncc1F	InChI=1S/C23H19ClFN5O2/c24-18-4-1-14(9-17(18)23(31)22-19(25)11-26-12-28-22)21-16-3-2-15(10-20(16)27-13-29-21)30-5-7-32-8-6-30/h1-4,9-13,23,31H,5-8H2	LGZAMQCFFYGHBM-UHFFFAOYSA-N	315966	US10172859, Example 389::US10172859, Example 390::US10172859, Example 412::US11065253, Example 412::US9732094, Example 412::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-fluoro- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954820	383542624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660087	COc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-21-12-26-13-28-23(21)24(31)18-10-15(2-5-19(18)25)22-17-4-3-16(11-20(17)27-14-29-22)30-6-8-33-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	OTIHBNMSAHVGDN-UHFFFAOYSA-N	315985	US10172859, Example 408::US10172859, Example 409::US10172859, Example 413::US11065253, Example 422::US9732094, Example 413::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315985&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954975	383542636							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660089	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20ClN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	UUXRSDRUPOEDCD-UHFFFAOYSA-N	315991	US10172859, Example 414::US10172859, Example 415::US10172859, Example 432::US11065253, Example 432::US9732094, Example 432::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954873	383542638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660091	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20ClN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	UUXRSDRUPOEDCD-UHFFFAOYSA-N	315991	US10172859, Example 414::US10172859, Example 415::US10172859, Example 432::US11065253, Example 432::US9732094, Example 432::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954873	383542638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660093	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2occc12	InChI=1S/C25H20ClN5O3/c26-20-4-1-15(11-19(20)24(32)23-18-5-8-34-25(18)30-14-29-23)22-17-3-2-16(12-21(17)27-13-28-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	GYTMHNSZACGKTK-UHFFFAOYSA-N	315993	US10172859, Example 416::US11065253, Example 416::US9732094, Example 416::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 8.88 (s, 1H), 8.20 (d, J = 2.5, 1H), 8.03 (d,J = 2.2, 1H), 7.84 (d, J = 9.4, 1H), 7.72 (dd, J = 8.2,2.2, 1H), 7.65 (d, J = 8.3, 1H), 7.52 (dd, J = 9.4, 2.6,1H), 7.26 (d, J = 2.5, 1H), 7.20 (d, J = 2.5, 1H), 6.88-6.72 (m, 1H), 6.46 (s, 1H), 3.82-3.76 (m, 4H),3.48-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315993&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966405	383542639							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660095	Cc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WWJSWAADUXDPSA-UHFFFAOYSA-N	315994	US10172859, Example 417::US10172859, Example 418::US10172859, Example 419::US11065253, Example 419::US9732094, Example 419::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954968	383542640							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660097	Cc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WWJSWAADUXDPSA-UHFFFAOYSA-N	315994	US10172859, Example 417::US10172859, Example 418::US10172859, Example 419::US11065253, Example 419::US9732094, Example 419::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954968	383542640							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660099	Cc1cncnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-12-26-13-28-22(15)24(31)19-10-16(2-5-20(19)25)23-18-4-3-17(11-21(18)27-14-29-23)30-6-8-32-9-7-30/h2-5,10-14,24,31H,6-9H2,1H3	WWJSWAADUXDPSA-UHFFFAOYSA-N	315994	US10172859, Example 417::US10172859, Example 418::US10172859, Example 419::US11065253, Example 419::US9732094, Example 419::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methyl- pyrimidin-4-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315994&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954968	383542640							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660101	Cn1cnc2c(ncnc12)C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22FN7O2/c1-32-14-31-23-22(29-13-30-25(23)32)24(34)15-2-5-19(26)18(10-15)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	KPHDWKKIMJUEFT-UHFFFAOYSA-N	315997	US10172859, Example 420::US11065253, Example 420::US9732094, Example 420::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.91 (s, 1H), 8.55 (s, 1H), 7.82-7.73 (m,2H), 7.56-7.47 (m, 2H), 7.40-7.31 (m, 1H),7.19 (d, J = 1.3, 1H), 6.43 (d, J = 3.0, 1H), 6.30 (d,J = 5.2, 1H), 3.83 (s, 3H), 3.81-3.75 (m, 4H), 3.47-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315997&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954901	383542641							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660103	Cn1cnc2c(ncnc12)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H21F2N7O2/c1-33-13-32-23-22(30-12-31-25(23)33)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	YUNSFHVJJPXAJL-UHFFFAOYSA-N	315922	US10172859, Example 346::US10172859, Example 347::US10172859, Example 421::US11065253, Example 421::US9732094, Example 421::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(9-methyl- 9H-purin-6-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315922&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954880	383542591							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660105	COc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-24-22(26-6-7-27-24)23(31)18-12-15(2-5-19(18)25)21-17-4-3-16(13-20(17)28-14-29-21)30-8-10-33-11-9-30/h2-7,12-14,23,31H,8-11H2,1H3	QZQZLQSAQQUISA-UHFFFAOYSA-N	315987	US10172859, Example 410::US10172859, Example 411::US10172859, Example 422::US11065253, Example 411::US9732094, Example 422::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315987&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954914	383542637							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660107	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3Cl)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21ClFN7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)16-9-17(19(27)10-18(16)26)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	GOQCONHIZCNEEW-UHFFFAOYSA-N	316000	US10172859, Example 423::US9732094, Example 423::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.14 (s,1H), 8.83 (s, 1H), 8.69 (s, 1H), 8.01 (d, J = 7.8,1H), 7.71-7.63 (m, 2H), 7.59 (dd, J = 9.4, 2.5, 1H),7.22 (d, J = 2.4, 1H), 6.87 (d, J = 6.3, 1H), 6.66 (d,J = 6.3, 1H), 4.25 (s, 3H), 3.84-3.73 (m, 4H), 3.52-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316000&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954792	383542642							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660109	CN1CCN(C1=O)c1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C27H26FN7O3/c1-33-8-9-35(27(33)37)26-24(29-6-7-30-26)25(36)17-2-5-21(28)20(14-17)23-19-4-3-18(15-22(19)31-16-32-23)34-10-12-38-13-11-34/h2-7,14-16,25,36H,8-13H2,1H3	YOWUVCMEWRRBJL-UHFFFAOYSA-N	316001	1-(3-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl)- 3-methyl- imidazolidin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.50 (d, J = 2.4, 1H), 8.43 (d, J = 2.4, 1H), 7.69-7.59 (m, 2H), 7.59-7.49 (m, 2H), 7.35 (t, J = 9.2,1H), 7.19 (d, J = 1.9, 1H), 6.23 (d, J = 4.4, 1H), 5.95(d, J = 5.3, 1H), 3.85 (t, J = 7.8, 2H), 3.82-3.73 (m,4H), 3.52-3.40 (m, 6H), 2.78 (s, 3H).::US10172859, Example 424::US11065253, Example 424::US9732094, Example 424	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316001&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966406	383542643							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660111	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1N1CCCC1=O	InChI=1S/C27H25FN6O3/c28-21-6-3-17(26(36)25-27(30-8-7-29-25)34-9-1-2-23(34)35)14-20(21)24-19-5-4-18(15-22(19)31-16-32-24)33-10-12-37-13-11-33/h3-8,14-16,26,36H,1-2,9-13H2	HAKJGZGJAFAOJJ-UHFFFAOYSA-N	316002	1-(3-{[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}pyrazin-2-yl)- pyrrolidin-2-one1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.61 (d, J = 2.4, 1H), 8.52 (d, J = 2.4, 1H), 7.65-7.56 (m, 2H), 7.56-7.49 (m, 2H), 7.36 (t, J = 9.5,1H), 7.19 (s, 1H), 6.02 (s, 2H), 3.89-3.82 (m,1H), 3.81-3.74 (m, 4H), 3.74-3.64 (m, 1H),3.50-3.39 (m, 4H), 2.57-2.41 (m, 2H), 2.17-2.08 (m, 1H), 2.07-1.98 (m, 1H).::US10172859, Example 425::US11065253, Example 425::US9732094, Example 425	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316002&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954798	383542644							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660113	Cc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	KQRMNHUHQIGCCV-UHFFFAOYSA-N	316003	US10172859, Example 426::US10172859, Example 427::US10172859, Example 428::US11065253, Example 428::US9732094, Example 428::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954949	383542645							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660115	Cc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	KQRMNHUHQIGCCV-UHFFFAOYSA-N	316003	US10172859, Example 426::US10172859, Example 427::US10172859, Example 428::US11065253, Example 428::US9732094, Example 428::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954949	383542645							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660117	Cc1nccnc1C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O2/c1-15-22(27-7-6-26-15)24(31)19-12-16(2-5-20(19)25)23-18-4-3-17(13-21(18)28-14-29-23)30-8-10-32-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	KQRMNHUHQIGCCV-UHFFFAOYSA-N	316003	US10172859, Example 426::US10172859, Example 427::US10172859, Example 428::US11065253, Example 428::US9732094, Example 428::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316003&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954949	383542645							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660119	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H19ClFN5O2S/c26-19-11-20(27)18(10-17(19)24(33)23-16-3-8-35-25(16)31-13-30-23)22-15-2-1-14(9-21(15)28-12-29-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	WSXQRVAJDUCHLW-UHFFFAOYSA-N	316006	US10172859, Example 429::US11065253, Example 429::US9732094, Example 429::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 9.05 (s, 1H), 8.46 (d, J = 5.6, 1H), 7.75 (d,J = 7.6, 1H), 7.72 (d, J = 9.6, 1H), 7.61 (d, J = 5.6,1H), 7.55-7.49 (m, 2H), 7.20 (d, J = 5.0, 1H), 7.19-7.17 (m, 1H), 6.42 (d, J = 5.1, 1H), 3.80-3.75 (m,4H), 3.46-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316006&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954864	383542646							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660121	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H20ClN5O2S/c26-20-4-1-15(11-19(20)24(32)23-18-5-10-34-25(18)30-14-29-23)22-17-3-2-16(12-21(17)27-13-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	HTXWHKWAFKZIOM-UHFFFAOYSA-N	316007	US10172859, Example 430::US11065253, Example 430::US9732094, Example 430::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.06 (s,1H), 9.04 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.89 (d,J = 2.1, 1H), 7.76 (d, J = 9.4, 1H), 7.73 (dd, J = 8.2,2.2, 1H), 7.69 (d, J = 8.3, 1H), 7.62 (d, J = 5.5, 1H),7.47 (dd, J = 9.5, 2.6, 1H), 7.20-7.16 (m, 2H),6.47 (d, J = 4.9, 1H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316007&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966407	383542647							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660123	Cn1cnc2ncnc(C(O)c3cc(c(F)cc3F)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H21F2N7O2/c1-33-13-32-25-23(33)22(30-12-31-25)24(35)17-9-16(18(26)10-19(17)27)21-15-3-2-14(8-20(15)28-11-29-21)34-4-6-36-7-5-34/h2-3,8-13,24,35H,4-7H2,1H3	VGKMJMNCNMRSEO-UHFFFAOYSA-N	315961	(R)-[2,4-Difluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol (Ena 2)see racemate::US10172859, Example 384::US10172859, Example 386::US10172859, Example 431::US11065253, Example 431::US9732094, Example 431	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315961&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954829	383542620							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660125	OC(c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20ClN5O3/c26-19-4-1-15(11-18(19)24(32)23-25-20(5-8-34-25)27-13-30-23)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	UUXRSDRUPOEDCD-UHFFFAOYSA-N	315991	US10172859, Example 414::US10172859, Example 415::US10172859, Example 432::US11065253, Example 432::US9732094, Example 432::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954873	383542638							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660127	Cn1cnc2ncnc(C(O)c3ccc(F)c(c3)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C25H22FN7O2/c1-32-14-31-25-23(32)22(29-13-30-25)24(34)15-2-5-19(26)18(10-15)21-17-4-3-16(11-20(17)27-12-28-21)33-6-8-35-9-7-33/h2-5,10-14,24,34H,6-9H2,1H3	ZMFSOBGRZBTGEQ-UHFFFAOYSA-N	316010	US10172859, Example 433::US11065253, Example 433::US9732094, Example 433::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(7-methyl- 7H-purin-6-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.90 (s, 1H), 8.60 (s, 1H), 7.68-7.60 (m,2H), 7.56 (dd, J = 9.4, 2.8, 1H), 7.52 (dd, J = 9.4,2.4, 1H), 7.44-7.38 (m, 1H), 7.19 (d, J = 2.3, 1H),6.84 (d, J = 5.5, 1H), 6.37 (d, J = 5.4, 1H), 4.04 (s,3H), 3.81-3.75 (m, 4H), 3.47-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316010&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954982	383542648							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660129	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2occc12	InChI=1S/C25H20FN5O3/c26-20-4-1-15(24(32)23-18-5-8-34-25(18)30-14-29-23)11-19(20)22-17-3-2-16(12-21(17)27-13-28-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	OLAPWLJTKZZIJG-UHFFFAOYSA-N	316011	US10172859, Example 434::US9732094, Example 434::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.89 (s, 1H), 8.18 (d, J = 2.5, 1H), 7.77-7.72(m, 2H), 7.54-7.47 (m, 2H), 7.40 (t, J = 9.5, 1H),7.36 (d, J = 2.5, 1H), 7.20 (d, J = 2.2, 1H), 6.71 (d,J = 4.2, 1H), 6.13 (d, J = 4.2, 1H), 3.81-3.76 (m,4H), 3.47-3.42 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316011&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696483	383542649							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660131	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22ClFN4O3/c1-30-22(3-2-4-23(30)32)25(33)17-12-18(20(27)13-19(17)26)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	WYNSFINJUTXESJ-UHFFFAOYSA-N	315959	6-{[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 382::US10172859, Example 383::US10172859, Example 435::US11065253, Example 435::US9732094, Example 435	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315959&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696425	383542619							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660133	Cn1c(cccc1=O)C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H22F2N4O3/c1-30-22(3-2-4-23(30)32)25(33)18-12-17(19(26)13-20(18)27)24-16-6-5-15(11-21(16)28-14-29-24)31-7-9-34-10-8-31/h2-6,11-14,25,33H,7-10H2,1H3	TYEQLJVPHLCAPI-UHFFFAOYSA-N	315957	6-{[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]hydroxy- methyl}-1-methyl-1H- pyridin-2-one (Ena 2)see racemate::US10172859, Example 380::US10172859, Example 381::US10172859, Example 436::US11065253, Example 436::US9732094, Example 436	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315957&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954779	383542618							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660135	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2sccc12	InChI=1S/C25H20FN5O2S/c26-20-4-1-15(24(32)23-18-5-10-34-25(18)30-14-29-23)11-19(20)22-17-3-2-16(12-21(17)27-13-28-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	OPFDCXZLQFZOBI-UHFFFAOYSA-N	316014	US10172859, Example 437::US11065253, Example 437::US9732094, Example 437::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyrimidin-4-yl- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 9.08 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.78-7.73(m, 2H), 7.61 (d, J = 5.6, 1H), 7.54-7.46 (m, 2H),7.43-7.36 (m, 1H), 7.21-7.18 (m, 1H), 7.13 (d,J = 3.9, 1H), 6.12 (d, J = 3.9, 1H), 3.82-3.73 (m,4H), 3.48-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316014&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966408	383542650							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660137	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H20FN5O2S/c26-19-4-1-15(24(32)23-25-20(5-10-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-8-33-9-7-31/h1-5,10-14,24,32H,6-9H2	RGLFQGKKFJSQEU-UHFFFAOYSA-N	316015	US10172859, Example 438::US11065253, Example 438::US9732094, Example 438::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 9.07 (s, 1H), 8.46 (s, 1H), 8.45 (s, 1H), 7.78-7.73 (m, 2H), 7.60 (d, J = 5.5, 1H), 7.52-7.46 (m,2H), 7.41-7.36 (m, 1H), 7.20-7.18 (m, 1H),7.11 (d, J = 3.9, 1H), 6.12 (d, J = 3.9, 1H), 3.80-3.75 (m, 4H), 3.46-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316015&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966409	383542651							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660139	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccsc12	InChI=1S/C25H19F2N5O2S/c26-18-11-19(27)17(24(33)23-25-20(3-8-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-6-34-7-5-32/h1-3,8-13,24,33H,4-7H2	YGCAKHZAOVAPCB-UHFFFAOYSA-N	316016	US10172859, Example 439::US11065253, Example 439::US9732094, Example 439::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.07 (s,1H), 9.05 (s, 1H), 8.47 (d, J = 5.6, 1H), 7.76 (t,J = 8.0, 1H), 7.61 (d, J = 5.6, 1H), 7.54-7.46 (m,3H), 7.21-7.16 (m, 2H), 6.32 (d, J = 4.8, 1H), 3.80-3.74 (m, 4H), 3.46-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316016&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954767	383542652							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660141	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19ClFN5O3/c26-18-11-19(27)17(10-16(18)24(33)23-25-20(3-6-35-25)28-12-31-23)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	RSORSFFEQKYDEH-UHFFFAOYSA-N	316017	US10172859, Example 440::US10172859, Example 441::US10172859, Example 452::US11065253, Example 452::US9732094, Example 452::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954743	383542653							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660143	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19ClFN5O3/c26-18-11-19(27)17(10-16(18)24(33)23-25-20(3-6-35-25)28-12-31-23)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	RSORSFFEQKYDEH-UHFFFAOYSA-N	316017	US10172859, Example 440::US10172859, Example 441::US10172859, Example 452::US11065253, Example 452::US9732094, Example 452::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954743	383542653							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660145	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(24(32)23-25-20(5-8-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	ALDDQCBBKGTAJI-UHFFFAOYSA-N	316019	US10172859, Example 442::US10172859, Example 443::US10172859, Example 471::US11065253, Example 471::US9732094, Example 471::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954900	383542654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660147	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(24(32)23-25-20(5-8-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	ALDDQCBBKGTAJI-UHFFFAOYSA-N	316019	US10172859, Example 442::US10172859, Example 443::US10172859, Example 471::US11065253, Example 471::US9732094, Example 471::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954900	383542654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660149	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19F2N5O3/c26-18-11-19(27)17(24(33)23-25-20(3-6-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JBAPBICUWYTLAE-UHFFFAOYSA-N	316021	US10172859, Example 444::US10172859, Example 445::US10172859, Example 446::US11065253, Example 446::US9732094, Example 446::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954757	383542655							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660151	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19F2N5O3/c26-18-11-19(27)17(24(33)23-25-20(3-6-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JBAPBICUWYTLAE-UHFFFAOYSA-N	316021	US10172859, Example 444::US10172859, Example 445::US10172859, Example 446::US11065253, Example 446::US9732094, Example 446::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954757	383542655							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660153	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19F2N5O3/c26-18-11-19(27)17(24(33)23-25-20(3-6-35-25)28-12-31-23)10-16(18)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	JBAPBICUWYTLAE-UHFFFAOYSA-N	316021	US10172859, Example 444::US10172859, Example 445::US10172859, Example 446::US11065253, Example 446::US9732094, Example 446::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316021&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954757	383542655							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660155	COc1cncnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-21-11-27-12-29-23(21)24(32)16-9-17(19(26)10-18(16)25)22-15-3-2-14(8-20(15)28-13-30-22)31-4-6-34-7-5-31/h2-3,8-13,24,32H,4-7H2,1H3	YEVSBZQJDDCQFS-UHFFFAOYSA-N	316024	US10172859, Example 447::US11065253, Example 447::US9732094, Example 447::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.14 (s,1H), 8.74 (s, 1H), 8.65 (s, 1H), 7.97 (d, J = 7.9,1H), 7.69-7.52 (m, 3H), 7.23 (d, J = 2.4, 1H), 6.43-6.32 (m, 2H), 4.01 (s, 3H), 3.80 (dd, J = 5.9, 3.9,4H), 3.47 (t, J = 4.9, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316024&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954881	383542656							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660157	COc1cncnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-21-11-27-12-29-23(21)24(32)17-9-16(18(25)10-19(17)26)22-15-3-2-14(8-20(15)28-13-30-22)31-4-6-34-7-5-31/h2-3,8-13,24,32H,4-7H2,1H3	MYZXVIJFUGZRRE-UHFFFAOYSA-N	316025	US10172859, Example 448::US11065253, Example 448::US9732094, Example 448::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(5-methoxy- pyrimidin-4-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.77 (s, 1H), 8.62 (s, 1H), 7.86 (t, J = 8.2,1H), 7.66-7.50 (m, 2H), 7.41 (t, J = 10.1, 1H),7.21 (d, J = 2.1, 1H), 6.32 (d, J = 6.2, 1H), 6.25 (d,J = 6.3, 1H), 3.97 (s, 3H), 3.78 (t, J = 4.9, 4H), 3.45(t, J = 4.9, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316025&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954903	383542657							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660159	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H19F4N5O3/c25-17-11-18(26)16(22(34)21-23(36-24(27)28)30-4-3-29-21)10-15(17)20-14-2-1-13(9-19(14)31-12-32-20)33-5-7-35-8-6-33/h1-4,9-12,22,24,34H,5-8H2	DZAPMQOMKQTQIL-UHFFFAOYSA-N	316027	(3-Difluoromethoxy- pyrazin-2-yl)-[2,4- difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol (Ena 2)see racemate::US10172859, Example 449::US10172859, Example 450::US10172859, Example 451::US9732094, Example 451	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954883	383542659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660161	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H19F4N5O3/c25-17-11-18(26)16(22(34)21-23(36-24(27)28)30-4-3-29-21)10-15(17)20-14-2-1-13(9-19(14)31-12-32-20)33-5-7-35-8-6-33/h1-4,9-12,22,24,34H,5-8H2	DZAPMQOMKQTQIL-UHFFFAOYSA-N	316027	(3-Difluoromethoxy- pyrazin-2-yl)-[2,4- difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol (Ena 2)see racemate::US10172859, Example 449::US10172859, Example 450::US10172859, Example 451::US9732094, Example 451	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954883	383542659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660163	OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H19F4N5O3/c25-17-11-18(26)16(22(34)21-23(36-24(27)28)30-4-3-29-21)10-15(17)20-14-2-1-13(9-19(14)31-12-32-20)33-5-7-35-8-6-33/h1-4,9-12,22,24,34H,5-8H2	DZAPMQOMKQTQIL-UHFFFAOYSA-N	316027	(3-Difluoromethoxy- pyrazin-2-yl)-[2,4- difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol (Ena 2)see racemate::US10172859, Example 449::US10172859, Example 450::US10172859, Example 451::US9732094, Example 451	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316027&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954883	383542659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660165	OC(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H19ClFN5O3/c26-18-11-19(27)17(10-16(18)24(33)23-25-20(3-6-35-25)28-12-31-23)22-15-2-1-14(9-21(15)29-13-30-22)32-4-7-34-8-5-32/h1-3,6,9-13,24,33H,4-5,7-8H2	RSORSFFEQKYDEH-UHFFFAOYSA-N	316017	US10172859, Example 440::US10172859, Example 441::US10172859, Example 452::US11065253, Example 452::US9732094, Example 452::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316017&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954743	383542653							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660167	COc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316031	US10172859, Example 453::US10172859, Example 454::US10172859, Example 467::US11065253, Example 467::US9732094, Example 467::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696480	383542660							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660169	COc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316031	US10172859, Example 453::US10172859, Example 454::US10172859, Example 467::US11065253, Example 467::US9732094, Example 467::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696480	383542660							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660171	COc1nccnc1[C@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3/t23-/m1/s1	YNJIBQSLMOPTQF-HSZRJFAPSA-N	335947	(R)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol::US9732094, Example 455	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335947&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954784	384988104							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660173	COc1nccnc1[C@@H](O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3/t23-/m0/s1	YNJIBQSLMOPTQF-QHCPKHFHSA-N	335948	(S)-(2-Chloro-4- fluoro-5-(7- morprholin-4-yl- quinazolin-4-yl)- pnenyl]-(3-methoxy- pyrazin-2-yl)- methanol::US9732094, Example 456	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=335948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=335948&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118955009	384988105							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660175	Cc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O2/c1-14-22(28-5-4-27-14)24(32)17-11-18(20(26)12-19(17)25)23-16-3-2-15(10-21(16)29-13-30-23)31-6-8-33-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3	RUVXWPONRWXAMN-UHFFFAOYSA-N	316035	US10172859, Example 457::US11065253, Example 457::US9732094, Example 457::[2-Chloro-4-fluoro-5- (7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.13 (s,1H), 8.43 (d, J = 2.5, 1H), 8.36 (d, J = 2.5, 1H), 7.99(d, J = 7.8, 1H), 7.67-7.60 (m, 2H), 7.57 (dd,J = 9.4, 2.5, 1H), 7.22 (d, J = 2.4, 1H), 6.44 (d,J = 5.9, 1H), 6.25 (d, J = 5.6, 1H), 3.86-3.72 (m,4H), 3.52-3.42 (m, 4H), 2.74 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316035&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954904	383542663							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660177	COc1ccc(nn1)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QSHKWVVOMGJBJQ-UHFFFAOYSA-N	316036	US10172859, Example 458::US10172859, Example 459::US10172859, Example 460::US11065253, Example 460::US9732094, Example 460::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.07 (d, J = 2.2, 1H), 7.89 (d, J = 9.5, 1H), 7.73-7.67 (m, 2H), 7.63 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.24-7.19 (m, 2H), 6.59 (d,J = 4.8, 1H), 6.28 (d, J = 4.8, 1H), 4.00 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954970	383542664							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660179	COc1ccc(nn1)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QSHKWVVOMGJBJQ-UHFFFAOYSA-N	316036	US10172859, Example 458::US10172859, Example 459::US10172859, Example 460::US11065253, Example 460::US9732094, Example 460::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.07 (d, J = 2.2, 1H), 7.89 (d, J = 9.5, 1H), 7.73-7.67 (m, 2H), 7.63 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.24-7.19 (m, 2H), 6.59 (d,J = 4.8, 1H), 6.28 (d, J = 4.8, 1H), 4.00 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954970	383542664							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660181	COc1ccc(nn1)C(O)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H22ClN5O3/c1-32-22-7-6-20(28-29-22)24(31)18-12-15(2-5-19(18)25)23-17-4-3-16(13-21(17)26-14-27-23)30-8-10-33-11-9-30/h2-7,12-14,24,31H,8-11H2,1H3	QSHKWVVOMGJBJQ-UHFFFAOYSA-N	316036	US10172859, Example 458::US10172859, Example 459::US10172859, Example 460::US11065253, Example 460::US9732094, Example 460::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(6-methoxy- pyridazin-3-yl)- methanol (Ena 1)1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.07 (d, J = 2.2, 1H), 7.89 (d, J = 9.5, 1H), 7.73-7.67 (m, 2H), 7.63 (d, J = 8.2, 1H), 7.54 (dd,J = 9.5, 2.6, 1H), 7.24-7.19 (m, 2H), 6.59 (d,J = 4.8, 1H), 6.28 (d, J = 4.8, 1H), 4.00 (s, 3H), 3.82-3.75 (m, 4H), 3.48-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316036&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954970	383542664							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660183	Cn1cnc2ccnc(C(O)c3ccc(F)c(c3)-c3ncnc4cc(ccc34)N3CCOCC3)c12	InChI=1S/C26H23FN6O2/c1-32-15-31-21-6-7-28-24(25(21)32)26(34)16-2-5-20(27)19(12-16)23-18-4-3-17(13-22(18)29-14-30-23)33-8-10-35-11-9-33/h2-7,12-15,26,34H,8-11H2,1H3	NSLYODQLWMOYDK-UHFFFAOYSA-N	316039	US10172859, Example 461::US11065253, Example 461::US9732094, Example 461::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- 3H-imidazo[4,5-c]- pyridin-4-yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.33 (s, 1H), 8.25 (d, J = 5.5, 1H), 7.62 (d,J = 5.5, 1H), 7.61-7.50 (m, 4H), 7.42-7.37 (m,1H), 7.19 (d, J = 2.3, 1H), 6.61 (d, J = 5.5, 1H), 6.43(d, J = 5.4, 1H), 4.01 (s, 3H), 3.80-3.74 (m, 4H),3.46-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954736	383542665							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660185	CCc1nccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H24FN5O2/c1-2-21-24(28-8-7-27-21)25(32)16-3-6-20(26)19(13-16)23-18-5-4-17(14-22(18)29-15-30-23)31-9-11-33-12-10-31/h3-8,13-15,25,32H,2,9-12H2,1H3	OHCNFGVQULWIRH-UHFFFAOYSA-N	316040	US10172859, Example 462::US9732094, Example 462::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-iodo- pyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.62 (d, J = 2.4, 1H), 8.37 (d, J = 2.4, 1H), 7.69-7.61 (m, 2H), 7.58-7.49 (m, 2H), 7.44-7.36 (m,1H), 7.22-7.17 (m, 1H), 6.33 (d, J = 5.7, 1H), 6.17(d, J = 5.7, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316040&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966411	383542666							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660187	CCOc1cccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C26H25FN4O3/c1-2-34-23-4-3-9-28-25(23)26(32)17-5-8-21(27)20(14-17)24-19-7-6-18(15-22(19)29-16-30-24)31-10-12-33-13-11-31/h3-9,14-16,26,32H,2,10-13H2,1H3	UTBHMAUJPAIFTH-UHFFFAOYSA-N	316041	(3-Ethoxy-pyridin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.14 (dd, J = 4.7, 1.2, 1H), 7.63-7.55 (m, 2H),7.55-7.47 (m, 2H), 7.41 (dd, J = 8.3, 1.3, 1H),7.38-7.31 (m, 1H), 7.29 (dd, J = 8.3, 4.7, 1H),7.21-7.17 (m, 1H), 6.07 (d, J = 6.3, 1H), 5.79 (d,J = 6.6, 1H), 4.06 (q, J = 7.0, 2H), 3.81-3.75 (m,4H), 3.47-3.41 (m, 4H), 1.28 (t, J = 6.9, 3H).::US10172859, Example 463::US11065253, Example 463::US9732094, Example 463	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316041&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954738	383542667							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660189	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1OC(F)F	InChI=1S/C24H20F3N5O3/c25-18-4-1-14(22(33)21-23(35-24(26)27)29-6-5-28-21)11-17(18)20-16-3-2-15(12-19(16)30-13-31-20)32-7-9-34-10-8-32/h1-6,11-13,22,24,33H,7-10H2	WUQGHORGFLTBFV-UHFFFAOYSA-N	316042	(3-Difluoromethoxy- pyrazin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.51 (d, J = 2.6, 1H), 8.28 (d, J = 2.6, 1H), 7.86-7.55 (m, 3H), 7.54-7.49 (m, 2H), 7.43-7.36 (m,1H), 7.22-7.17 (m, 1H), 6.30 (d, J = 5.6, 1H), 6.10(d, J = 4.9, 1H), 3.83-3.73 (m, 4H), 3.48-3.40 (m,4H).::US10172859, Example 464::US9732094, Example 464	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316042&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954927	383542668							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660191	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C24H20ClFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	IKPAUHLVUSUQBQ-UHFFFAOYSA-N	315616	(3-Chloro-pyridin-2-yl)- [4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.56 (dd, J = 4.6, 1.4, 1H), 7.92 (dd, J = 8.1, 1.4, 1H), 7.64-7.59 (m, 2H), 7.54-7.49 (m, 2H), 7.40- 7.34 (m, 2H), 7.22-7.17 (m, 1H), 6.21 (s, 1H), 6.18-6.09 (m, 1H), 3.81-3.73 (m, 4H), 3.48- 3.40 (m, 4H)::US10172859, Example 42::US10172859, Example 465::US10172859, Example 466::US11065253, Example 42::US9732094, Example 466	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292074	383542366							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660193	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Cl	InChI=1S/C24H20ClFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	IKPAUHLVUSUQBQ-UHFFFAOYSA-N	315616	(3-Chloro-pyridin-2-yl)- [4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.56 (dd, J = 4.6, 1.4, 1H), 7.92 (dd, J = 8.1, 1.4, 1H), 7.64-7.59 (m, 2H), 7.54-7.49 (m, 2H), 7.40- 7.34 (m, 2H), 7.22-7.17 (m, 1H), 6.21 (s, 1H), 6.18-6.09 (m, 1H), 3.81-3.73 (m, 4H), 3.48- 3.40 (m, 4H)::US10172859, Example 42::US10172859, Example 465::US10172859, Example 466::US11065253, Example 42::US9732094, Example 466	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315616&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86292074	383542366							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660195	COc1nccnc1C(O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21F2N5O3/c1-33-24-22(27-4-5-28-24)23(32)17-11-16(18(25)12-19(17)26)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	BWGYCECICQRZBD-UHFFFAOYSA-N	316031	US10172859, Example 453::US10172859, Example 454::US10172859, Example 467::US11065253, Example 467::US9732094, Example 467::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanol (Ena 1)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316031&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117696480	383542660							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660197	COc1nccnc1C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H21ClFN5O3/c1-33-24-22(27-4-5-28-24)23(32)16-11-17(19(26)12-18(16)25)21-15-3-2-14(10-20(15)29-13-30-21)31-6-8-34-9-7-31/h2-5,10-13,23,32H,6-9H2,1H3	YNJIBQSLMOPTQF-UHFFFAOYSA-N	315820	US10172859, Example 241::US10172859, Example 242::US10172859, Example 258::US10172859, Example 468::US11065253, Example 258::US9732094, Example 258::[2-Chloro-4-fluoro-5- [7-(2,2,3,3,5,5,6,6- octadeuteriomorpholin- 4-yl)quinazolin-4- yl]phenyl]-(3- methoxypyrazin-2- yl)methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=315820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=315820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954785	383542509							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660199	OC(c1cccnn1)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClN5O2/c24-19-6-3-15(12-18(19)23(30)20-2-1-7-27-28-20)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	NKTVIVGVBABPLJ-UHFFFAOYSA-N	316047	US10172859, Example 469::US10172859, Example 470::US10172859, Example 479::US11065253, Example 479::US9732094, Example 479::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridazin-3-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954953	383542669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660201	OC(c1cccnn1)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClN5O2/c24-19-6-3-15(12-18(19)23(30)20-2-1-7-27-28-20)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	NKTVIVGVBABPLJ-UHFFFAOYSA-N	316047	US10172859, Example 469::US10172859, Example 470::US10172859, Example 479::US11065253, Example 479::US9732094, Example 479::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridazin-3-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954953	383542669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660203	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12	InChI=1S/C25H20FN5O3/c26-19-4-1-15(24(32)23-25-20(5-8-34-25)27-13-30-23)11-18(19)22-17-3-2-16(12-21(17)28-14-29-22)31-6-9-33-10-7-31/h1-5,8,11-14,24,32H,6-7,9-10H2	ALDDQCBBKGTAJI-UHFFFAOYSA-N	316019	US10172859, Example 442::US10172859, Example 443::US10172859, Example 471::US11065253, Example 471::US9732094, Example 471::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316019&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954900	383542654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660205	Cc1cccnc1C(O)c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C25H23FN4O2/c1-16-3-2-8-27-23(16)25(31)17-4-7-21(26)20(13-17)24-19-6-5-18(14-22(19)28-15-29-24)30-9-11-32-12-10-30/h2-8,13-15,25,31H,9-12H2,1H3	GBYLJBVPBPYLRC-UHFFFAOYSA-N	316050	US10172859, Example 472::US9732094, Example 472::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methyl- pyridin-2-yl)methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.08 (s,1H), 8.43-8.39 (m, 1H), 7.63-7.57 (m, 1H),7.56-7.49 (m, 4H), 7.39-7.32 (m, 1H), 7.28-7.23 (m, 1H), 7.21-7.17 (m, 1H), 6.09 (s, 1H),6.01 (s, 1H), 3.82-3.73 (m, 4H), 3.48-3.40 (m,4H), 2.28 (s, 3H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316050&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954737	383542670							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660207	COc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Br)c1	InChI=1S/C25H22BrFN4O3/c1-33-17-12-20(26)24(28-13-17)25(32)15-2-5-21(27)19(10-15)23-18-4-3-16(11-22(18)29-14-30-23)31-6-8-34-9-7-31/h2-5,10-14,25,32H,6-9H2,1H3	ZLJHQDMTGQKOCX-UHFFFAOYSA-N	316051	(3-bromo-5-methoxy- pyridin-2-yl)-[4- fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.31 (d, J = 2.6, 1H), 7.70 (d, J = 2.6, 1H), 7.62-7.56 (m, 2H), 7.54-7.50 (m, 2H), 7.39-7.33 (m,1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.01(d, J = 6.1, 1H), 3.84 (s, 3H), 3.80-3.75 (m, 4H),3.46-3.41 (m, 4H).::US10172859, Example 473::US11065253, Example 473::US9732094, Example 473	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316051&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954989	383542671							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660209	OC(c1cn2ccsc2n1)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C24H19F2N5O2S/c25-18-11-19(26)17(23(32)21-12-31-5-8-34-24(31)29-21)10-16(18)22-15-2-1-14(9-20(15)27-13-28-22)30-3-6-33-7-4-30/h1-2,5,8-13,23,32H,3-4,6-7H2	IHQLBTUWFJZXJZ-UHFFFAOYSA-N	316052	US10172859, Example 474::US11065253, Example 474::US9732094, Example 474::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]imidazo- [2,1-b]thiazol-6-yl- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 7.85 (d, J = 4.5, 1H), 7.71-7.68 (m, 1H), 7.62-7.55 (m, 1H), 7.54-7.51 (m, 2H), 7.26 (t, J = 9.1,1H), 7.21-7.17 (m, 2H), 6.18-6.13 (m, 2H),3.80-3.75 (m, 4H), 3.47-3.41 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 12500								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118966412	383542672							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660211	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1OC(F)(F)F	InChI=1S/C25H20F4N4O3/c26-19-6-3-15(24(34)23-21(2-1-7-30-23)36-25(27,28)29)12-18(19)22-17-5-4-16(13-20(17)31-14-32-22)33-8-10-35-11-9-33/h1-7,12-14,24,34H,8-11H2	OBAUKTZXPTWSGG-UHFFFAOYSA-N	316053	US10172859, Example 475::US11065253, Example 475::US9732094, Example 475::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-trifluoro- methoxypyridin-2-yl)- methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.11 (s,1H), 8.61 (dd, J = 4.6, 1.3, 1H), 7.87 (dp, J = 8.4,1.6, 1H), 7.69-7.57 (m, 2H), 7.57-7.46 (m, 3H),7.40 (dd, J = 9.9, 8.4, 1H), 7.21 (d, J = 1.9, 1H), 6.26(d, J = 5.9, 1H), 6.13 (d, J = 5.9, 1H), 3.89-3.65 (m,4H), 3.54-3.38 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316053&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954867	383542673							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660213	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccnc1C(F)(F)F	InChI=1S/C24H19F4N5O2/c25-18-4-1-14(22(34)21-23(24(26,27)28)30-6-5-29-21)11-17(18)20-16-3-2-15(12-19(16)31-13-32-20)33-7-9-35-10-8-33/h1-6,11-13,22,34H,7-10H2	SRYGCCCAHLEYHR-UHFFFAOYSA-N	316055	US10172859, Example 476::US11065253, Example 476::US9732094, Example 476::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-trifluoro- methylpyrazin-2-yl)- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 9.00 (d, J = 2.3, 1H), 8.77 (d, J = 2.3, 1H), 7.66(dd, J = 6.9, 2.3, 1H), 7.63-7.59 (m, 1H), 7.56-7.50 (m, 2H), 7.43-7.37 (m, 1H), 7.21-7.18 (m,1H), 6.54 (d, J = 5.7, 1H), 6.21 (d, J = 4.3, 1H), 3.81-3.74 (m, 4H), 3.48-3.40 (m, 4H).	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>25000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316055&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954911	383542675							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660215	OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncccc1Br	InChI=1S/C24H20BrFN4O2/c25-19-2-1-7-27-23(19)24(31)15-3-6-20(26)18(12-15)22-17-5-4-16(13-21(17)28-14-29-22)30-8-10-32-11-9-30/h1-7,12-14,24,31H,8-11H2	AOTYAPLNLRAVPH-UHFFFAOYSA-N	316056	(3-bromo-pyridin-2- yl)-[4-fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]methanol1H NMR (400 MHz, DMSO-d6) ppm = 9.09 (s,1H), 8.60 (dd, J = 4.6, 1.4, 1H), 8.08 (dd, J = 8.1,1.5, 1H), 7.65-7.59 (m, 2H), 7.54-7.50 (m, 2H),7.41-7.34 (m, 1H), 7.29 (dd, J = 8.1, 4.6, 1H),7.21-7.18 (m, 1H), 6.20 (d, J = 6.3, 1H), 6.12 (d,J = 6.3, 1H), 3.82-3.74 (m, 4H), 3.49-3.40 (m,4H).::US10172859, Example 478::US11065253, Example 478::US9732094, Example 478	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	<10000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316056&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954893	383542676							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
660217	OC(c1cccnn1)c1cc(ccc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1	InChI=1S/C23H20ClN5O2/c24-19-6-3-15(12-18(19)23(30)20-2-1-7-27-28-20)22-17-5-4-16(13-21(17)25-14-26-22)29-8-10-31-11-9-29/h1-7,12-14,23,30H,8-11H2	NKTVIVGVBABPLJ-UHFFFAOYSA-N	316047	US10172859, Example 469::US10172859, Example 470::US10172859, Example 479::US11065253, Example 479::US9732094, Example 479::[2-Chloro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyridazin-3-yl- methanol (Ena 2)see racemate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 20000								US Patent		10.7270/Q2J67K1S		aid1796994	US9732094	Fuchss, T; Emde, U; Buchstaller, H; Mederski, W	8/15/2017	6/23/2019	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=316047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=316047&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118954953	383542669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	1UJL,2L0W,2L4R,2N7G,4HQA,5VA1,5VA2,5VA3,6SYG,7CN0,7CN1	Potassium voltage-gated channel subfamily H member 2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Potassium voltage-gated channel subfamily H member 2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
707130	Cc1nsc(n1)-c1nnc2CN(CCn12)C(=O)c1ccc(F)cc1	InChI=1S/C15H13FN6OS/c1-9-17-14(24-20-9)13-19-18-12-8-21(6-7-22(12)13)15(23)10-2-4-11(16)5-3-10/h2-5H,6-8H2,1H3	UHNVQJPBRBMNNN-UHFFFAOYSA-N	50112183	CHEMBL3608684::US10214533, Compound 1::US9969738, 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 50000							US Patent		10.7270/Q21J9D35		aid1797718	US10214533	Hoveyda, H; Dutheuil, G; Fraser, G	2/26/2019	10/20/2019	Ogeda	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112183	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112183&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			81689815	319493542		CHEMBL3608684					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
707131	Cc1nsc(n1)-c1nnc2CN(CCn12)C(=O)c1ccc(Cl)cc1	InChI=1S/C15H13ClN6OS/c1-9-17-14(24-20-9)13-19-18-12-8-21(6-7-22(12)13)15(23)10-2-4-11(16)5-3-10/h2-5H,6-8H2,1H3	UXOOGKCYBVVXAO-UHFFFAOYSA-N	357792	US10214533, Compound 2::(4-chlorophenyl)(3-(3- methyl-1,2,4-thiadiazol-5- yl)-5,6-dihydro- [1,2,4]triazolo[4,3- a]pyrazin-7(8H)- yl)methanone::US9969738, 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 35000							US Patent		10.7270/Q21J9D35		aid1797718	US10214533	Hoveyda, H; Dutheuil, G; Fraser, G	2/26/2019	10/20/2019	Ogeda	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=357792	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=357792&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86300058	386397340							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714783	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)COC1)c1cccc(OCCNCCCF)c1 |r|	InChI=1S/C27H33F2N3O2/c1-19-14-23-22-8-2-3-9-24(22)31-25(23)26(32(19)16-27(29)17-33-18-27)20-6-4-7-21(15-20)34-13-12-30-11-5-10-28/h2-4,6-9,15,19,26,30-31H,5,10-14,16-18H2,1H3	AFLLEYDANXDWBB-UHFFFAOYSA-N	361409	3-Fluoro-N-(2-(3-((1R,3R)-2-((3-fluorooxetan-3-yl)methyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenoxy)ethyl)propan-1-amine::US10221173, Example 1::US10590132, Example 1::US11046689, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361409	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361409&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277187	386400795							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714784	COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H32F3N3O2/c1-17-14-20-19-6-3-4-7-22(19)31-25(20)26(32(17)16-24(28)29)21-15-18(8-9-23(21)33-2)34-13-12-30-11-5-10-27/h3-4,6-9,15,17,24,26,30-31H,5,10-14,16H2,1-2H3	HLEVNGBZPKFBLQ-UHFFFAOYSA-N	361414	N-(2-(3-((1R,3R)-2-(2,2-difluoroethyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-4-methoxyphenoxy)ethyl)-3-fluoropropan-1-amine::US10221173, Example 6::US10590132, Example 6::US11046689, Example 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361414	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361414&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277092	386400800							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714785	COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H31F4N3O2/c1-17-14-20-19-6-3-4-7-22(19)32-24(20)25(33(17)16-26(28,29)30)21-15-18(8-9-23(21)34-2)35-13-12-31-11-5-10-27/h3-4,6-9,15,17,25,31-32H,5,10-14,16H2,1-2H3	ORXOIENTRQRMKN-UHFFFAOYSA-N	361415	3-Fluoro-N-(2-(4-methoxy-3-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenoxy)ethyl)propan-1-amine::US10221173, Example 7::US10590132, Example 7::US11046689, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361415	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361415&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277033	386400801							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714786	COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C27H34F3N3O3/c1-18-14-21-20-6-3-4-7-23(20)32-25(21)26(33(18)16-27(29,30)17-34)22-15-19(8-9-24(22)35-2)36-13-12-31-11-5-10-28/h3-4,6-9,15,18,26,31-32,34H,5,10-14,16-17H2,1-2H3	AQBZHJBCKSTPQK-UHFFFAOYSA-N	361416	2,2-Difluoro-3-((1R,3R)-1-(5-(2-((3-fluoropropyl)amino)ethoxy)-2-methoxyphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)propan-1-ol::US10221173, Example 8::US10590132, Example 8::US11046689, Example 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361416&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135276982	386400802							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714787	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C25H27F6N3O/c1-15-13-17-16-5-2-3-6-19(16)33-23(17)24(34(15)14-25(29,30)31)21-18(27)7-8-20(22(21)28)35-12-11-32-10-4-9-26/h2-3,5-8,15,24,32-33H,4,9-14H2,1H3	IURRISDHEMQJRJ-UHFFFAOYSA-N	361417	Preparation of N-(2-(2,4-difluoro-3-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenoxy)ethyl)-3-fluoropropan-1-amine::US10221173, Example 9::US10590132, Example 9::US11046689, Example 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361417	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361417&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277098	386400803							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714788	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1F |r|	InChI=1S/C25H28F5N3O/c1-16-13-19-18-5-2-3-6-22(18)32-23(19)24(33(16)15-25(28,29)30)20-14-17(7-8-21(20)27)34-12-11-31-10-4-9-26/h2-3,5-8,14,16,24,31-32H,4,9-13,15H2,1H3	SLTNEYDLIVCLGL-UHFFFAOYSA-N	361418	Preparation of 3-fluoro-N-(2-(4-fluoro-3-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenoxy)ethyl)propan-1-amine::US10221173, Example 10::US10590132, Example 10::US11046689, Example 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361418	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361418&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277085	386400804							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714789	COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H30F5N3O2/c1-16-14-18-17-6-3-4-7-19(17)33-24(18)25(34(16)15-26(29,30)31)22-20(35-2)8-9-21(23(22)28)36-13-12-32-11-5-10-27/h3-4,6-9,16,25,32-33H,5,10-15H2,1-2H3	HDRIOVZPSXLMEK-UHFFFAOYSA-N	361419	Preparation of 3-fluoro-N-(2-(2-fluoro-4-methoxy-3-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenoxy)ethyl)propan-1-amine::US10221173, Example 11::US10590132, Example 82::US11046689, Example 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361419	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361419&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277004	386400805							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714790	COc1cnc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C25H30F4N4O2/c1-16-12-18-17-6-3-4-7-20(17)32-23(18)24(33(16)15-25(27,28)29)19-13-22(31-14-21(19)34-2)35-11-10-30-9-5-8-26/h3-4,6-7,13-14,16,24,30,32H,5,8-12,15H2,1-2H3	CGWBNWSADUPPAJ-UHFFFAOYSA-N	361420	Preparation of 3-fluoro-N-(2-((5-methoxy-4-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pyridin-2-yl)oxy)ethyl)propan-1-amine::US10221173, Example 12::US10590132, Example 12::US11046689, Example 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361420	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361420&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135276978	386400806							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714791	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)COC1)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C27H31F4N3O2/c1-17-13-19-18-5-2-3-6-21(18)33-25(19)26(34(17)14-27(31)15-35-16-27)23-20(29)7-8-22(24(23)30)36-12-11-32-10-4-9-28/h2-3,5-8,17,26,32-33H,4,9-16H2,1H3	XTDQQPAIIZAWPS-UHFFFAOYSA-N	361421	Preparation of N-(2-(2,4-difluoro-3-((1R,3R)-2-((3-fluorooxetan-3-yl)methyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenoxy)ethyl)-3-fluoropropan-1-amine::US10221173, Example 13::US10590132, Example 13::US11046689, Example 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361421	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361421&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277007	386400807							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714792	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C26H30F5N3O2/c1-16-13-18-17-5-2-3-6-20(17)33-24(18)25(34(16)14-26(30,31)15-35)22-19(28)7-8-21(23(22)29)36-12-11-32-10-4-9-27/h2-3,5-8,16,25,32-33,35H,4,9-15H2,1H3	MULLTNVDYCQIAT-UHFFFAOYSA-N	361422	3-((1R,3R)-1-(2,6-difluoro-3-(2-((3-fluoropropyl)amino)ethoxy)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol::US10221173, Example 14::US10590132, Example 14::US11046689, Example 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361422	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361422&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277137	386400808							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714793	C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C26H29F6N3O2/c1-15-11-18-17-12-16(28)3-5-20(17)34-24(18)25(35(15)13-26(31,32)14-36)22-19(29)4-6-21(23(22)30)37-10-9-33-8-2-7-27/h3-6,12,15,25,33-34,36H,2,7-11,13-14H2,1H3	WEBMNFBVPLSXNC-UHFFFAOYSA-N	361423	3-((1R,3R)-1-(2,6-difluoro-3-(2-((3-fluoropropyl)amino)ethoxy)phenyl)-6-fluoro-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol::US10221173, Example 15::US10590132, Example 15::US11046689, Example 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361423	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361423&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263188	386400809							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714794	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1C |r|	InChI=1S/C26H31F4N3O/c1-17-8-9-19(34-13-12-31-11-5-10-27)15-21(17)25-24-22(20-6-3-4-7-23(20)32-24)14-18(2)33(25)16-26(28,29)30/h3-4,6-9,15,18,25,31-32H,5,10-14,16H2,1-2H3	GDFODPGZJWMOLV-UHFFFAOYSA-N	361425	3-fluoro-N-(2- (4-methyl-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 17::US10590132, Example 17::US11046689, Example 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361425	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361425&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277198	386400811							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714795	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(C)cc(OCCNCCCF)c1 |r|	InChI=1S/C26H31F4N3O/c1-17-12-19(15-20(13-17)34-11-10-31-9-5-8-27)25-24-22(21-6-3-4-7-23(21)32-24)14-18(2)33(25)16-26(28,29)30/h3-4,6-7,12-13,15,18,25,31-32H,5,8-11,14,16H2,1-2H3	HUUWWYUNNNZAAI-UHFFFAOYSA-N	361426	3-fluoro-N-(2- (3-methyl-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 18::US10590132, Example 18::US11046689, Example 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361426&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277197	386400812							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714796	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cccc(OCCNCCCF)c1C |r|	InChI=1S/C26H31F4N3O/c1-17-15-21-20-7-3-4-9-22(20)32-24(21)25(33(17)16-26(28,29)30)19-8-5-10-23(18(19)2)34-14-13-31-12-6-11-27/h3-5,7-10,17,25,31-32H,6,11-16H2,1-2H3	GRTREOMLNXYRCK-UHFFFAOYSA-N	361428	3-fluoro-N-(2- (2-methyl-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 20::US10590132, Example 20::US11046689, Example 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361428	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361428&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343516	386400814							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714797	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1Cl |r|	InChI=1S/C25H28ClF4N3O/c1-16-13-19-18-5-2-3-6-22(18)32-23(19)24(33(16)15-25(28,29)30)20-14-17(7-8-21(20)26)34-12-11-31-10-4-9-27/h2-3,5-8,14,16,24,31-32H,4,9-13,15H2,1H3	YMHAKHHOKBUDNZ-UHFFFAOYSA-N	361430	N-(2-(4- chloro-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 22::US10590132, Example 22::US11046689, Example 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361430&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277211	386400816							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714798	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1C#N |r|	InChI=1S/C26H28F4N4O/c1-17-13-22-20-5-2-3-6-23(20)33-24(22)25(34(17)16-26(28,29)30)21-14-19(8-7-18(21)15-31)35-12-11-32-10-4-9-27/h2-3,5-8,14,17,25,32-33H,4,9-13,16H2,1H3	XPZBVPYCFOTFST-UHFFFAOYSA-N	361431	4-(2-((3- fluoropropyl) amino)ethoxy)- 2-((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)benzonitrile::US10221173, Example 23::US10590132, Example 23::US11046689, Example 23	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361431&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277068	386400817							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714799	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cccc(OCCNCCCF)c1F |r|	InChI=1S/C25H28F5N3O/c1-16-14-19-17-6-2-3-8-20(17)32-23(19)24(33(16)15-25(28,29)30)18-7-4-9-21(22(18)27)34-13-12-31-11-5-10-26/h2-4,6-9,16,24,31-32H,5,10-15H2,1H3	BPPHZYQGDXOLKS-UHFFFAOYSA-N	361432	3-fluoro-N-(2- (2-fluoro-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 24::US10590132, Example 24::US11046689, Example 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361432&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343569	386400818							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714800	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cccc(OCCNCCCF)c1Cl |r|	InChI=1S/C25H28ClF4N3O/c1-16-14-19-17-6-2-3-8-20(17)32-23(19)24(33(16)15-25(28,29)30)18-7-4-9-21(22(18)26)34-13-12-31-11-5-10-27/h2-4,6-9,16,24,31-32H,5,10-15H2,1H3	QJEINMSDKUUKPD-UHFFFAOYSA-N	361433	N-(2-(2- chloro-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 25::US10590132, Example 25::US11046689, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361433	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361433&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277070	386400819							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714801	COc1ccc(OCCNCCCF)c(C)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C27H33F4N3O2/c1-17-15-20-19-7-4-5-8-21(19)33-25(20)26(34(17)16-27(29,30)31)24-18(2)22(9-10-23(24)35-3)36-14-13-32-12-6-11-28/h4-5,7-10,17,26,32-33H,6,11-16H2,1-3H3	XTISMUCMNDPXNU-UHFFFAOYSA-N	361434	3-fluoro-N-(2- (4-methoxy-2- methyl-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 26::US10590132, Example 26::US11046689, Example 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361434	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361434&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343526	386400820							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714802	COc1c(F)cc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H30F5N3O2/c1-16-12-19-18-6-3-4-7-22(18)33-23(19)24(34(16)15-26(29,30)31)20-13-17(14-21(28)25(20)35-2)36-11-10-32-9-5-8-27/h3-4,6-7,13-14,16,24,32-33H,5,8-12,15H2,1-2H3	UKXDASKXRNNVRK-UHFFFAOYSA-N	361435	3-fluoro-N-(2- (3-fluoro-4- methoxy-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 27::US10590132, Example 27::US11046689, Example 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361435	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361435&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277116	386400821							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714803	COc1cc(F)c(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H30F5N3O2/c1-16-12-18-17-6-3-4-7-21(17)33-24(18)25(34(16)15-26(29,30)31)19-13-23(20(28)14-22(19)35-2)36-11-10-32-9-5-8-27/h3-4,6-7,13-14,16,25,32-33H,5,8-12,15H2,1-2H3	AYEKDICMTFVKOQ-UHFFFAOYSA-N	361436	3-fluoro-N-(2- (2-fluoro-4- methoxy-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 28::US10590132, Example 28::US11046689, Example 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361436	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361436&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277166	386400822							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714804	COc1c(F)cc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H29F6N3O2/c1-15-12-17-16-6-3-4-7-19(16)34-23(17)24(35(15)14-26(30,31)32)21-22(29)20(13-18(28)25(21)36-2)37-11-10-33-9-5-8-27/h3-4,6-7,13,15,24,33-34H,5,8-12,14H2,1-2H3	IWVPIRCUNQVONB-UHFFFAOYSA-N	361437	N-(2-(2,5- difluoro-4- methoxy-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 29::US10590132, Example 29::US11046689, Example 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361437	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361437&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277164	386400823							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714805	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)cc(F)c1F |r|	InChI=1S/C25H27F6N3O/c1-15-11-18-17-5-2-3-6-21(17)33-23(18)24(34(15)14-25(29,30)31)19-12-16(13-20(27)22(19)28)35-10-9-32-8-4-7-26/h2-3,5-6,12-13,15,24,32-33H,4,7-11,14H2,1H3	HBQZYLKZANANNP-UHFFFAOYSA-N	361438	N-(2-(3,4- difluoro-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 30::US10590132, Example 30::US11046689, Example 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361438	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361438&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277165	386400824							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714806	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(F)cc(OCCNCCCF)c1F |r|	InChI=1S/C25H27F6N3O/c1-15-11-18-17-5-2-3-6-20(17)33-23(18)24(34(15)14-25(29,30)31)19-12-16(27)13-21(22(19)28)35-10-9-32-8-4-7-26/h2-3,5-6,12-13,15,24,32-33H,4,7-11,14H2,1H3	BLNIJBCDTYVWCH-UHFFFAOYSA-N	361439	N-(2-(2,5- difluoro-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 31::US10590132, Example 31::US11046689, Example 31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361439	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361439&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343797	386400825							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714807	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)c(F)cc(OCCNCCCF)c1F |r|	InChI=1S/C25H26F7N3O/c1-14-11-16-15-5-2-3-6-18(15)34-23(16)24(35(14)13-25(30,31)32)20-21(28)17(27)12-19(22(20)29)36-10-9-33-8-4-7-26/h2-3,5-6,12,14,24,33-34H,4,7-11,13H2,1H3	IRQIJKRXGXGNRK-UHFFFAOYSA-N	361440	3-fluoro-N-(2- (2,4,5- trifluoro-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 32::US10590132, Example 32::US11046689, Example 32	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361440	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361440&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343481	386400826							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714808	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)ccc(OCCNCCCF)c1C |r|	InChI=1S/C26H30F5N3O/c1-16-14-19-18-6-3-4-7-21(18)33-24(19)25(34(16)15-26(29,30)31)23-17(2)22(9-8-20(23)28)35-13-12-32-11-5-10-27/h3-4,6-9,16,25,32-33H,5,10-15H2,1-2H3	MLFYCSZCDRJXFS-UHFFFAOYSA-N	361441	3-fluoro-N-(2- (4-fluoro-2- methyl-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 33::US10590132, Example 33::US11046689, Example 33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361441	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361441&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277105	386400827							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714809	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cccc(OCCNCCCF)n1 |r|	InChI=1S/C24H28F4N4O/c1-16-14-18-17-6-2-3-7-19(17)31-22(18)23(32(16)15-24(26,27)28)20-8-4-9-21(30-20)33-13-12-29-11-5-10-25/h2-4,6-9,16,23,29,31H,5,10-15H2,1H3	PZYPIKZGEWFIHB-UHFFFAOYSA-N	361442	3-fluoro-N-(2- ((6-((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl) propan-1-amine::US10221173, Example 34::US10590132, Example 34::US11046689, Example 34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361442	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361442&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277104	386400828							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714810	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccn1 |r|	InChI=1S/C24H28F4N4O/c1-16-13-19-18-5-2-3-6-20(18)31-22(19)23(32(16)15-24(26,27)28)21-14-17(7-10-30-21)33-12-11-29-9-4-8-25/h2-3,5-7,10,14,16,23,29,31H,4,8-9,11-13,15H2,1H3	DJOJMGVIZNWNIP-UHFFFAOYSA-N	361443	3-fluoro-N-(2- ((2-((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)oxy)ethyl) propan-1-amine::US10221173, Example 35::US10590132, Example 35::US11046689, Example 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361443	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361443&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277168	386400829							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714811	COc1ncc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C25H30F4N4O2/c1-16-12-19-18-6-3-4-7-21(18)32-22(19)23(33(16)15-25(27,28)29)20-13-17(14-31-24(20)34-2)35-11-10-30-9-5-8-26/h3-4,6-7,13-14,16,23,30,32H,5,8-12,15H2,1-2H3	LPYNBSIKESUTGC-UHFFFAOYSA-N	361444	3-fluoro-N-(2- ((6-methoxy-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-3- yl)oxy)ethyl) propan-1-amine::US10221173, Example 36::US10590132, Example 36::US11046689, Example 36	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361444&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277167	386400830							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714812	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)cnc1C |r|	InChI=1S/C25H30F4N4O/c1-16-12-21-19-6-3-4-7-22(19)32-23(21)24(33(16)15-25(27,28)29)20-13-18(14-31-17(20)2)34-11-10-30-9-5-8-26/h3-4,6-7,13-14,16,24,30,32H,5,8-12,15H2,1-2H3	NUGZEPKLLMSKCR-UHFFFAOYSA-N	361445	3-fluoro-N-(2- ((6-methyl-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-3- yl)oxy)ethyl) propan-1-amine::US10221173, Example 37::US10590132, Example 37::US11046689, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3500							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361445&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343482	386400831							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714813	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cncc(OCCNCCCF)c1C |r|	InChI=1S/C25H30F4N4O/c1-16-12-19-18-6-3-4-7-21(18)32-23(19)24(33(16)15-25(27,28)29)20-13-31-14-22(17(20)2)34-11-10-30-9-5-8-26/h3-4,6-7,13-14,16,24,30,32H,5,8-12,15H2,1-2H3	ZUPWETAMZUYNQX-UHFFFAOYSA-N	361446	3-fluoro-N-(2- ((4-methyl-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-3- yl)oxy)ethyl) propan-1-amine::US10221173, Example 38::US10590132, Example 38::US11046689, Example 38	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361446	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361446&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343730	386400832							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714814	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ncc1F |r|	InChI=1S/C24H27F5N4O/c1-15-11-17-16-5-2-3-6-20(16)32-22(17)23(33(15)14-24(27,28)29)18-12-21(31-13-19(18)26)34-10-9-30-8-4-7-25/h2-3,5-6,12-13,15,23,30,32H,4,7-11,14H2,1H3	AHJHVDUYHAGZRS-UHFFFAOYSA-N	361447	3-fluoroN-(2- ((5-fluoro-4- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl) propan-1-amine::US10221173, Example 39::US10590132, Example 39::US11046689, Example 39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361447	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361447&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277210	386400833							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714815	COc1ccc(NCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H32F4N4O/c1-17-14-20-19-6-3-4-7-22(19)33-24(20)25(34(17)16-26(28,29)30)21-15-18(8-9-23(21)35-2)32-13-12-31-11-5-10-27/h3-4,6-9,15,17,25,31-33H,5,10-14,16H2,1-2H3	TUAOOZUFWRCNSA-UHFFFAOYSA-N	361448	N1-(3- fluoropropyl)- N2-(4- methoxy-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenyl) ethane-1,2- diamine::US10221173, Example 40::US10590132, Example 40::US11046689, Example 40	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361448&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277155	386400834							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714816	COc1ncc(NCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C25H31F4N5O/c1-16-12-19-18-6-3-4-7-21(18)33-22(19)23(34(16)15-25(27,28)29)20-13-17(14-32-24(20)35-2)31-11-10-30-9-5-8-26/h3-4,6-7,13-14,16,23,30-31,33H,5,8-12,15H2,1-2H3	LUYUYCNQIRCBNT-UHFFFAOYSA-N	361449	N1-(3- fluoropropyl)- N2-(6- methoxy-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-3- yl)ethane-1,2- diamine::US10221173, Example 41::US10590132, Example 41::US11046689, Example 41	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361449	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361449&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277158	386400835							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714817	COc1cnc(NCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C25H31F4N5O/c1-16-12-18-17-6-3-4-7-20(17)33-23(18)24(34(16)15-25(27,28)29)19-13-22(32-14-21(19)35-2)31-11-10-30-9-5-8-26/h3-4,6-7,13-14,16,24,30,33H,5,8-12,15H2,1-2H3,(H,31,32)	ZDPAZDLUXFSIMM-UHFFFAOYSA-N	361450	N1-( 3- fluoropropyl)- N2-(5- methoxy-4- (1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)ethane-1,2- diamine::US10221173, Example 42::US10590132, Example 42::US11046689, Example 42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361450	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361450&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277150	386400836							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714818	COc1ccc(NCCNCCCF)nc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C25H31F4N5O/c1-16-14-18-17-6-3-4-7-19(17)32-22(18)24(34(16)15-25(27,28)29)23-20(35-2)8-9-21(33-23)31-13-12-30-11-5-10-26/h3-4,6-9,16,24,30,32H,5,10-15H2,1-2H3,(H,31,33)	XRHYTDKIDXNPOV-UHFFFAOYSA-N	361451	N1-(3- fluoropropyl)- N2-(5- methoxy-6- ((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)ethane-1,2- diamine::US10221173, Example 43::US10590132, Example 43::US11046689, Example 43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361451	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361451&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277149	386400837							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714819	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1cc(OCCNCCCF)ccc1Cl |r|	InChI=1S/C26H31ClF3N3O2/c1-17-13-20-19-5-2-3-6-23(19)32-24(20)25(33(17)15-26(29,30)16-34)21-14-18(7-8-22(21)27)35-12-11-31-10-4-9-28/h2-3,5-8,14,17,25,31-32,34H,4,9-13,15-16H2,1H3	SDKAQMVPMOVEBU-UHFFFAOYSA-N	361452	3-((1R,3R)-1- (2-chloro-5-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan- 1-ol::US10221173, Example 44::US10590132, Example 44::US11046689, Example 44	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361452	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361452&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277062	386400838							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714820	Cc1c(ccc(c1[C@@H]2c3c(c4ccccc4[nH]3)C[C@H](N2CC(CO)(F)F)C)F)OCCNCCCF	InChI=1S/C27H33F4N3O2/c1-17-14-20-19-6-3-4-7-22(19)33-25(20)26(34(17)15-27(30,31)16-35)24-18(2)23(9-8-21(24)29)36-13-12-32-11-5-10-28/h3-4,6-9,17,26,32-33,35H,5,10-16H2,1-2H3	AJSOGGXGYQZCBL-UHFFFAOYSA-N	361453	2,2-difluoro-3- ((1R,3R)-1-(6- fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy)- 2- methylphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 45::US10590132, Example 45::US11046689, Example 45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1500							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361453	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361453&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	H09	7QVJ	135277061	386400839							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714821	COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccc(F)cc21 |r|	InChI=1S/C27H33F4N3O3/c1-17-12-21-20-13-18(29)4-6-23(20)33-25(21)26(34(17)15-27(30,31)16-35)22-14-19(5-7-24(22)36-2)37-11-10-32-9-3-8-28/h4-7,13-14,17,26,32-33,35H,3,8-12,15-16H2,1-2H3	UYAMZNPPYFCASE-UHFFFAOYSA-N	361454	2,2-difluoro-3- ((1R,3R)-6- fluoro-1-(5-(2- ((3- fluoropropyl) amino)ethoxy)- 2- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 46::US10590132, Example 46::US11046689, Example 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361454	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361454&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343539	386400840							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714822	COc1ccc(O[C@H](C)CNCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H36F3N3O3/c1-18-13-22-21-7-4-5-8-24(21)33-26(22)27(34(18)16-28(30,31)17-35)23-14-20(9-10-25(23)36-3)37-19(2)15-32-12-6-11-29/h4-5,7-10,14,18-19,27,32-33,35H,6,11-13,15-17H2,1-3H3	CJXIOPIGXQHWQR-UHFFFAOYSA-N	361455	2,2-difluoro-3- ((1R,3R)-1-(5- (((R)-1-((3- fluoropropyl) amino)propan- 2-yl)oxy)-2- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 47::US10590132, Example 47::US11046689, Example 47	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361455	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361455&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343812	386400841							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714823	COc1ccc(O[C@@H](C)CNCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H36F3N3O3/c1-18-13-22-21-7-4-5-8-24(21)33-26(22)27(34(18)16-28(30,31)17-35)23-14-20(9-10-25(23)36-3)37-19(2)15-32-12-6-11-29/h4-5,7-10,14,18-19,27,32-33,35H,6,11-13,15-17H2,1-3H3	CJXIOPIGXQHWQR-UHFFFAOYSA-N	361456	2,2-difluoro-3- ((1R,3R)-1-(5- (((S)-1-((3- fluoropropyl) amino)propan- 2-yl)oxy)-2- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 48::US10590132, Example 48::US11046689, Example 48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361456	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361456&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277065	386400842							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714824	COc1ccc(OC[C@H](C)NCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H36F3N3O3/c1-18(32-12-6-11-29)15-37-20-9-10-25(36-3)23(14-20)27-26-22(21-7-4-5-8-24(21)33-26)13-19(2)34(27)16-28(30,31)17-35/h4-5,7-10,14,18-19,27,32-33,35H,6,11-13,15-17H2,1-3H3	DLSUONXFKGICCB-UHFFFAOYSA-N	361457	2,2-difluoro-3- ((1R,3R)-1-(5- ((S)-2-((3- fluoropropyl) amino)propoxy)- 2- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 49::US10590132, Example 49::US11046689, Example 49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361457	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361457&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343693	386400843							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714825	COc1ccc(OC[C@@H](C)NCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H36F3N3O3/c1-18(32-12-6-11-29)15-37-20-9-10-25(36-3)23(14-20)27-26-22(21-7-4-5-8-24(21)33-26)13-19(2)34(27)16-28(30,31)17-35/h4-5,7-10,14,18-19,27,32-33,35H,6,11-13,15-17H2,1-3H3	DLSUONXFKGICCB-UHFFFAOYSA-N	361458	2,2-difIuoro-3- ((1R,3R)-1-(5- ((S)-2-((3- fluoropropyl) amino)propoxy)- 2- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 50::US10590132, Example 50::US11046689, Example 50	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361458	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361458&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343767	386400844							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714826	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)F)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C25H28F5N3O/c1-15-13-17-16-5-2-3-6-19(16)32-24(17)25(33(15)14-21(28)29)22-18(27)7-8-20(23(22)30)34-12-11-31-10-4-9-26/h2-3,5-8,15,21,25,31-32H,4,9-14H2,1H3	AMFAUXJCRFTZMC-UHFFFAOYSA-N	361459	N-(2-(3- ((1R,3R)-2- (2,2- difluoroethyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 2,4- difluorophenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 51::US10590132, Example 51::US11046689, Example 51	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361459	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361459&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277144	386400845							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714827	COc1ccc(OCCNCCCF)cc1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H35F2N3O2/c1-19-16-22-21-6-3-4-7-24(21)32-26(22)27(33(19)18-28(30)10-11-28)23-17-20(8-9-25(23)34-2)35-15-14-31-13-5-12-29/h3-4,6-9,17,19,27,31-32H,5,10-16,18H2,1-2H3	AZAHWWKMQDSNOA-UHFFFAOYSA-N	361460	3-fluoro-N-(2- (3-((1R,3R)-2- ((1- fluorocyclopropyl) methyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 4- methoxyphenoxy) ethyl)propan- 1-amine::US10221173, Example 52::US10590132, Example 52::US11046689, Example 52	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5500							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361460	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361460&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263139	386400846							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714828	COc1ccc(OCCNCCCF)cc1[C@H]1N(C[C@H](C)C(O)=O)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H36FN3O4/c1-18(28(33)34)17-32-19(2)15-22-21-7-4-5-8-24(21)31-26(22)27(32)23-16-20(9-10-25(23)35-3)36-14-13-30-12-6-11-29/h4-5,7-10,16,18-19,27,30-31H,6,11-15,17H2,1-3H3,(H,33,34)	QKMLVXYNPFRPDX-UHFFFAOYSA-N	361461	(S)-3-((1R,3R)- 1-(5-(2-((3- fluoropropyl) amino)ethoxy)- 2- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 53::US10590132, Example 53::US11046689, Example 53	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361461	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361461&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277060	386400847							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714829	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(Cl)ccc(OCCNCCCF)c1F)C(O)=O |r|	InChI=1S/C27H32ClF2N3O3/c1-16(27(34)35)15-33-17(2)14-19-18-6-3-4-7-21(18)32-25(19)26(33)23-20(28)8-9-22(24(23)30)36-13-12-31-11-5-10-29/h3-4,6-9,16-17,26,31-32H,5,10-15H2,1-2H3,(H,34,35)	FYNCLYVDXSJMEF-UHFFFAOYSA-N	361462	(S)-3-((1R,3R)- 1-(6-chloro-2- fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 54::US10590132, Example 54::US11046689, Example 54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361462	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361462&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277063	386400848							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714830	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C)C(O)=O |r|	InChI=1S/C28H35F2N3O3/c1-17(28(34)35)16-33-18(2)15-21-20-7-4-5-8-23(20)32-26(21)27(33)25-19(3)24(10-9-22(25)30)36-14-13-31-12-6-11-29/h4-5,7-10,17-18,27,31-32H,6,11-16H2,1-3H3,(H,34,35)	KNSMOAXIFSMQRE-UHFFFAOYSA-N	361463	(S)-3-((1R,3R)-1-(6-fluoro-3-(2-((3-fluoropropyl)amino)ethoxy)-2-methylphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 55::US10590132, Example 55::US11046689, Example 55	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361463	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361463&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277020	386400849							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714831	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccc(F)cc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C)C(O)=O |r|	InChI=1S/C28H34F3N3O3/c1-16(28(35)36)15-34-17(2)13-21-20-14-19(30)5-7-23(20)33-26(21)27(34)25-18(3)24(8-6-22(25)31)37-12-11-32-10-4-9-29/h5-8,14,16-17,27,32-33H,4,9-13,15H2,1-3H3,(H,35,36)	JOFYCYZGTXIWEJ-UHFFFAOYSA-N	361465	(S)-3-((1R,3R)-6-fluoro-1-(6-fluoro-3-(2-((3-fluoropropyl)amino)ethoxy)-2-methylphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 57::US10590132, Example 57::US11046689, Example 57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361465	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361465&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277021	386400851							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714832	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1F)C(O)=O |r|	InChI=1S/C27H32F3N3O3/c1-16(27(34)35)15-33-17(2)14-19-18-6-3-4-7-21(18)32-25(19)26(33)23-20(29)8-9-22(24(23)30)36-13-12-31-11-5-10-28/h3-4,6-9,16-17,26,31-32H,5,10-15H2,1-2H3,(H,34,35)	IBQHPNIHSLVBKS-UHFFFAOYSA-N	361466	(S)-3-((1R,3R)- 1-(2,6- difluoro-3-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropano ic acid::US10221173, Example 58::US10590132, Example 58::US11046689, Example 58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361466	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361466&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343757	386400852							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714833	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccc(F)cc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1F)C(O)=O |r|	InChI=1S/C27H31F4N3O3/c1-15(27(35)36)14-34-16(2)12-19-18-13-17(29)4-6-21(18)33-25(19)26(34)23-20(30)5-7-22(24(23)31)37-11-10-32-9-3-8-28/h4-7,13,15-16,26,32-33H,3,8-12,14H2,1-2H3,(H,35,36)	UKHODDNBDQAQSM-UHFFFAOYSA-N	361467	(S)-3-((1R,3R)- 1-(2,6- difluoro-3-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-6- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 59::US10590132, Example 59::US11046689, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361467&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343700	386400853							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714834	C[C@@H]1Cc2c([nH]c3c(F)cccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C26H29F6N3O2/c1-15-12-17-16-4-2-5-19(29)23(16)34-24(17)25(35(15)13-26(31,32)14-36)21-18(28)6-7-20(22(21)30)37-11-10-33-9-3-8-27/h2,4-7,15,25,33-34,36H,3,8-14H2,1H3	YAFFSXHTUKRGED-UHFFFAOYSA-N	361468	3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropyl) amino)ethoxy) phenyl)-8- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 60::US10590132, Example 60::US11046689, Example 60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361468&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343794	386400854							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714835	C[C@@H]1Cc2c([nH]c3cc(F)ccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C26H29F6N3O2/c1-15-11-18-17-4-3-16(28)12-20(17)34-24(18)25(35(15)13-26(31,32)14-36)22-19(29)5-6-21(23(22)30)37-10-9-33-8-2-7-27/h3-6,12,15,25,33-34,36H,2,7-11,13-14H2,1H3	BRWPTTNZERDDAD-UHFFFAOYSA-N	361469	3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropyl) amino)ethoxy) phenyl)-7- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 61::US10590132, Example 61::US11046689, Example 61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361469&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263177	386400855							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714836	C[C@@H]1Cc2c([nH]c3cccc(F)c23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C26H29F6N3O2/c1-15-12-16-21-17(28)4-2-5-19(21)34-24(16)25(35(15)13-26(31,32)14-36)22-18(29)6-7-20(23(22)30)37-11-10-33-9-3-8-27/h2,4-7,15,25,33-34,36H,3,8-14H2,1H3	BPNUJHRNCIAXDS-UHFFFAOYSA-N	361470	3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropyl) amino)ethoxy) phenyl)-5- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 62::US10590132, Example 62::US11046689, Example 62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361470&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263124	386400856							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714837	C[C@@H]1Cc2c([nH]c3ccc(C)cc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C27H32F5N3O2/c1-16-4-6-21-18(12-16)19-13-17(2)35(14-27(31,32)15-36)26(25(19)34-21)23-20(29)5-7-22(24(23)30)37-11-10-33-9-3-8-28/h4-7,12,17,26,33-34,36H,3,8-11,13-15H2,1-2H3	FMJXKYQMUWYLBL-UHFFFAOYSA-N	361471	3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropyl) amino)ethoxy) phenyl)-3,6- dimethyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 63::US10590132, Example 63::US11046689, Example 63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361471&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343785	386400857							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714838	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1F |r|	InChI=1S/C25H29F5N4O2/c1-15-11-17-16-5-2-3-6-19(16)33-22(17)23(34(15)13-25(29,30)14-35)20-18(27)12-32-24(21(20)28)36-10-9-31-8-4-7-26/h2-3,5-6,12,15,23,31,33,35H,4,7-11,13-14H2,1H3	IMBVMXSLGHMNGP-UHFFFAOYSA-N	361472	3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 64::US10590132, Example 64::US11046689, Example 64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361472&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263216	386400858							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714839	C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1F |r|	InChI=1S/C25H28F6N4O2/c1-14-9-17-16-10-15(27)3-4-19(16)34-22(17)23(35(14)12-25(30,31)13-36)20-18(28)11-33-24(21(20)29)37-8-7-32-6-2-5-26/h3-4,10-11,14,23,32,34,36H,2,5-9,12-13H2,1H3	DHEZHAYVEMRCBF-UHFFFAOYSA-N	361473	3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)-6- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 65::US10590132, Example 65::US11046689, Example 65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361473&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343680	386400859							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714840	C[C@@H]1Cc2c([nH]c3ccc(C)cc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1F |r|	InChI=1S/C26H31F5N4O2/c1-15-4-5-20-17(10-15)18-11-16(2)35(13-26(30,31)14-36)24(23(18)34-20)21-19(28)12-33-25(22(21)29)37-9-8-32-7-3-6-27/h4-5,10,12,16,24,32,34,36H,3,6-9,11,13-14H2,1-2H3	OTBYGSVELWVBBB-UHFFFAOYSA-N	361474	3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)- 3,6-dimethyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 66::US10590132, Example 66::US11046689, Example 66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361474	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361474&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135267369	386400860							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714841	C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCN(C)CCCF)c1F |r|	InChI=1S/C26H30F6N4O2/c1-15-10-18-17-11-16(28)4-5-20(17)34-23(18)24(36(15)13-26(31,32)14-37)21-19(29)12-33-25(22(21)30)38-9-8-35(2)7-3-6-27/h4-5,11-12,15,24,34,37H,3,6-10,13-14H2,1-2H3	PWLJEUUITTYQFX-UHFFFAOYSA-N	361475	3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropyl) (methyl)amino) ethoxy)pyridin- 4-yl)-6- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 67::US10590132, Example 67::US11046689, Example 67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361475&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343733	386400861							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714842	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1cccc(OCCNCCCF)c1C(F)F |r|	InChI=1S/C27H32F5N3O2/c1-17-14-20-18-6-2-3-8-21(18)34-24(20)25(35(17)15-27(31,32)16-36)19-7-4-9-22(23(19)26(29)30)37-13-12-33-11-5-10-28/h2-4,6-9,17,25-26,33-34,36H,5,10-16H2,1H3	VHRKLEWIWPJKHZ-UHFFFAOYSA-N	361476	3-((1R,3R)-1- (2- (difluoromethyl)- 3-(2-((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan-1- ol::US10221173, Example 68::US10590132, Example 68::US11046689, Example 68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361476&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263485	386400862							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714843	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cccc(OCCNCCCF)c1C#N |r|	InChI=1S/C26H28F4N4O/c1-17-14-20-18-6-2-3-8-22(18)33-24(20)25(34(17)16-26(28,29)30)19-7-4-9-23(21(19)15-31)35-13-12-32-11-5-10-27/h2-4,6-9,17,25,32-33H,5,10-14,16H2,1H3	ULJTYTLJECJHEC-UHFFFAOYSA-N	361477	2-(2-((3- fluoropropyl) amino)ethoxy)- 6-((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)benzonitrile::US10221173, Example 69::US10590132, Example 69::US11046689, Example 69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361477&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343557	386400863							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714844	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1CO |r|	InChI=1S/C26H31F4N3O2/c1-17-13-22-20-5-2-3-6-23(20)32-24(22)25(33(17)16-26(28,29)30)21-14-19(8-7-18(21)15-34)35-12-11-31-10-4-9-27/h2-3,5-8,14,17,25,31-32,34H,4,9-13,15-16H2,1H3	BZZLWUMRMDWPKU-UHFFFAOYSA-N	361478	(4-(2-((3- fluoropropyl) amino)ethoxy)- 2-((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenyl) methanol::US10221173, Example 70::US10590132, Example 70::US11046689, Example 70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361478&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277036	386400864							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714845	COCc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C27H33F4N3O2/c1-18-14-23-21-6-3-4-7-24(21)33-25(23)26(34(18)17-27(29,30)31)22-15-20(9-8-19(22)16-35-2)36-13-12-32-11-5-10-28/h3-4,6-9,15,18,26,32-33H,5,10-14,16-17H2,1-2H3	HYOZMZHBMIBFGM-UHFFFAOYSA-N	361479	3-fluoro-N-(2- (4- (methoxymethyl)- 3-((1R,3R)- 3-methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 71::US10590132, Example 71::US11046689, Example 71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361479&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277157	386400865							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714846	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(F)cc(OCCNCCCF)c1 |r|	InChI=1S/C25H28F5N3O/c1-16-11-21-20-5-2-3-6-22(20)32-23(21)24(33(16)15-25(28,29)30)17-12-18(27)14-19(13-17)34-10-9-31-8-4-7-26/h2-3,5-6,12-14,16,24,31-32H,4,7-11,15H2,1H3	KSZIELZVRSLDCC-UHFFFAOYSA-N	361481	3-fluoro-N-(2- (3-fluoro-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 73::US10590132, Example 73::US11046689, Example 73	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361481&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277123	386400867							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714847	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1ccc(F)c(OCCNCCCF)c1 |r|	InChI=1S/C25H28F5N3O/c1-16-13-19-18-5-2-3-6-21(18)32-23(19)24(33(16)15-25(28,29)30)17-7-8-20(27)22(14-17)34-12-11-31-10-4-9-26/h2-3,5-8,14,16,24,31-32H,4,9-13,15H2,1H3	IYDSJLZRONWCJO-UHFFFAOYSA-N	361482	3-fluoro-N-(2- (2-fluoro-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 74::US10590132, Example 74::US11046689, Example 74	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361482&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343791	386400868							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714848	C[C@@H]1Cc2c([nH]c3ccccc23)[C@](C)(N1CC(F)(F)F)c1cccc(OCCNCCCF)c1 |r|	InChI=1S/C26H31F4N3O/c1-18-15-22-21-9-3-4-10-23(21)32-24(22)25(2,33(18)17-26(28,29)30)19-7-5-8-20(16-19)34-14-13-31-12-6-11-27/h3-5,7-10,16,18,31-32H,6,11-15,17H2,1-2H3	HDRWLCNLGWCVEP-UHFFFAOYSA-N	361483	N-(2-(3- ((1R,3R)-1,3- dimethyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 75::US10590132, Example 75::US11046689, Example 75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7700							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361483&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277143	386400869							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714849	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)CC1)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C27H31F4N3O/c1-17-15-19-18-5-2-3-6-21(18)33-25(19)26(34(17)16-27(31)9-10-27)23-20(29)7-8-22(24(23)30)35-14-13-32-12-4-11-28/h2-3,5-8,17,26,32-33H,4,9-16H2,1H3	NKDVESFPKPIDIQ-UHFFFAOYSA-N	361484	N-(2-(2,4- difluoro-3- ((1R,3R)-2-((1- fluorocyclopropyl) methyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 76::US10590132, Example 76::US11046689, Example 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361484&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343672	386400870							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714850	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(CC1)S(C)(=O)=O)c1c(F)ccc(OCCNCCCF)c1F |r|	InChI=1S/C28H34F3N3O3S/c1-18-16-20-19-6-3-4-7-22(19)33-26(20)27(34(18)17-28(10-11-28)38(2,35)36)24-21(30)8-9-23(25(24)31)37-15-14-32-13-5-12-29/h3-4,6-9,18,27,32-33H,5,10-17H2,1-2H3	YJEVVRPFVPWHRW-UHFFFAOYSA-N	361485	N-(2-(2,4- difluoro-3- ((1R,3R)-3- methyl-2-((1- (methylsulfonyl) cyclopropyl) methyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 77::US10590132, Example 77::US11046689, Example 77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361485&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277124	386400871							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714851	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(C)ccc(OCCNCCCF)c1C |r|	InChI=1S/C27H33F4N3O/c1-17-9-10-23(35-14-13-32-12-6-11-28)19(3)24(17)26-25-21(20-7-4-5-8-22(20)33-25)15-18(2)34(26)16-27(29,30)31/h4-5,7-10,18,26,32-33H,6,11-16H2,1-3H3	WCXZZJFDRDQAHJ-UHFFFAOYSA-N	361487	N-(2-(2,4- dimethyl-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 79::US10590132, Example 79::US11046689, Example 79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361487&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277093	386400873							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714852	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(C)ccc(OCCNCCCF)c1F |r|	InChI=1S/C26H30F5N3O/c1-16-8-9-21(35-13-12-32-11-5-10-27)23(28)22(16)25-24-19(18-6-3-4-7-20(18)33-24)14-17(2)34(25)15-26(29,30)31/h3-4,6-9,17,25,32-33H,5,10-15H2,1-2H3	VDHHNYKYQYVKKQ-UHFFFAOYSA-N	361488	3-fluoro-N-(2- (2-fluoro-4- methyl-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan-1- amine::US10221173, Example 80::US10590132, Example 80::US11046689, Example 80	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361488	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361488&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343663	386400874							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714853	COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C27H33F4N3O3/c1-17-14-19-18-6-3-4-7-20(18)33-25(19)26(34(17)15-27(30,31)16-35)23-21(36-2)8-9-22(24(23)29)37-13-12-32-11-5-10-28/h3-4,6-9,17,26,32-33,35H,5,10-16H2,1-2H3	AAUZPIUROATGLA-UHFFFAOYSA-N	361489	2,2-difluoro-3- ((1R,3R)-1-(2- fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy)- 6- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 81::US10590132, Example 81::US11046689, Example 81	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361489&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277095	386400875							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714854	COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H31F4N3O2/c1-16-14-18-17-6-3-4-7-19(17)32-25(18)26(33(16)15-22(28)29)23-20(34-2)8-9-21(24(23)30)35-13-12-31-11-5-10-27/h3-4,6-9,16,22,26,31-32H,5,10-15H2,1-2H3	OEZKRGIKZGSIQO-UHFFFAOYSA-N	361490	N-(2-(3- ((1R,3R)-2- (2,2- difluoroethyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 2-fluoro-4- methoxyphenoxy) ethyl)-3- fluoropropan- 1-amine::US10221173, Example 82::US11046689, Example 82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361490&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343758	386400876							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714855	COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H34F3N3O2/c1-18-16-20-19-6-3-4-7-21(19)33-26(20)27(34(18)17-28(31)10-11-28)24-22(35-2)8-9-23(25(24)30)36-15-14-32-13-5-12-29/h3-4,6-9,18,27,32-33H,5,10-17H2,1-2H3	OASZVQVLTRULBW-UHFFFAOYSA-N	361491	3-fluoro-N-(2- (2-fluoro-3- ((1R,3R)-2-((1- fluorocyclopropyl) methyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 4- methoxyphenoxy) ethyl)propan- 1-amine::US10221173, Example 83::US10590132, Example 83::US11046689, Example 83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361491&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277209	386400877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714856	COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC2(F)COC2)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C28H34F3N3O3/c1-18-14-20-19-6-3-4-7-21(19)33-26(20)27(34(18)15-28(31)16-36-17-28)24-22(35-2)8-9-23(25(24)30)37-13-12-32-11-5-10-29/h3-4,6-9,18,27,32-33H,5,10-17H2,1-2H3	FOIDHVYAXXYCBP-UHFFFAOYSA-N	361492	3-fluoro-N-(2- (2-fluoro-3- ((1R,3R)-2-((3- fluorooxetan- 3-yl)methyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 4- methoxyphenoxy) ethyl)propan- 1-amine::US10221173, Example 84::US10590132, Example 84::US11046689, Example 84	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361492&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343534	386400878							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714857	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1Cl |r|	InChI=1S/C26H30ClF4N3O2/c1-16-13-18-17-5-2-3-6-20(17)33-24(18)25(34(16)14-26(30,31)15-35)22-19(29)7-8-21(23(22)27)36-12-11-32-10-4-9-28/h2-3,5-8,16,25,32-33,35H,4,9-15H2,1H3	VIFIJKQSOSJVSI-UHFFFAOYSA-N	361493	3-((1R,3R)-1- (2-chloro-6- fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan- 1-ol::US10221173, Example 85::US10590132, Example 85::US11046689, Example 85	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361493	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361493&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263219	386400879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714858	COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccc(F)cc21 |r|	InChI=1S/C27H32F5N3O3/c1-16-12-19-18-13-17(29)4-5-20(18)34-25(19)26(35(16)14-27(31,32)15-36)23-21(37-2)6-7-22(24(23)30)38-11-10-33-9-3-8-28/h4-7,13,16,26,33-34,36H,3,8-12,14-15H2,1-2H3	ZCTQCBWQMVTHFN-UHFFFAOYSA-N	361494	2,2-difluoro-3- ((1R,3R)-6- fluoro-1-(2- fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy)- 6- methoxyphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 86::US10590132, Example 86::US11046689, Example 86	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361494&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343774	386400880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714859	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CCC#N)c1c(F)ccc(OCCNCCCF)c1C |r|	InChI=1S/C27H32F2N4O/c1-18-17-21-20-7-3-4-8-23(20)32-26(21)27(33(18)15-6-12-30)25-19(2)24(10-9-22(25)29)34-16-14-31-13-5-11-28/h3-4,7-10,18,27,31-32H,5-6,11,13-17H2,1-2H3	HXLFGYCGZKJHCO-UHFFFAOYSA-N	361495	3-((1R,3R)-1- (6-fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy)- 2- methylphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propanenitrile::US10221173, Example 87::US10590132, Example 87::US11046689, Example 87	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2400							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361495&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343614	386400881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714860	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)ccc(NCCNCCCF)c1F |r|	InChI=1S/C25H28F6N4/c1-15-13-17-16-5-2-3-6-19(16)34-23(17)24(35(15)14-25(29,30)31)21-18(27)7-8-20(22(21)28)33-12-11-32-10-4-9-26/h2-3,5-8,15,24,32-34H,4,9-14H2,1H3	RGTKJDJBFAYXID-UHFFFAOYSA-N	361496	N1-(2,4- difluoro-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenyl)-N2- (3- fluoropropyl)et hane-1,2- diamine::US10221173, Example 88::US10590132, Example 88::US11046689, Example 88	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361496&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277058	386400882							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714861	C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(NCCNCCCF)c1F |r|	InChI=1S/C26H30F6N4O/c1-15-11-18-17-12-16(28)3-5-20(17)35-24(18)25(36(15)13-26(31,32)14-37)22-19(29)4-6-21(23(22)30)34-10-9-33-8-2-7-27/h3-6,12,15,25,33-35,37H,2,7-11,13-14H2,1H3	OBXCEMCJDFYPCO-UHFFFAOYSA-N	361497	3-((1R,3R)-1- (2,6-difluoro- 3-((2-((3- fluoropropyl) amino)ethyl) amino)phenyl)-6- fluoro-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan- 1-ol::US10221173, Example 89::US10590132, Example 89::US11046689, Example 89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361497	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361497&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343541	386400883							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714862	COc1ccc(NCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H31F5N4O/c1-16-14-18-17-6-3-4-7-19(17)34-24(18)25(35(16)15-26(29,30)31)22-21(36-2)9-8-20(23(22)28)33-13-12-32-11-5-10-27/h3-4,6-9,16,25,32-34H,5,10-15H2,1-2H3	QVJHGBKZCZUPLJ-UHFFFAOYSA-N	361498	N1-(2-fluoro- 4-methoxy-3- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenyl)-N2- (3- fluoropropyl) ethane-1,2- diamine::US10221173, Example 90::US10590132, Example 90::US11046689, Example 90	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361498&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277072	386400884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714863	COc1cc(F)c(NCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C26H31F5N4O/c1-16-12-18-17-6-3-4-7-21(17)34-24(18)25(35(16)15-26(29,30)31)19-13-22(20(28)14-23(19)36-2)33-11-10-32-9-5-8-27/h3-4,6-7,13-14,16,25,32-34H,5,8-12,15H2,1-2H3	QFUPEQWFGZHTBD-UHFFFAOYSA-N	361499	N1-(2-fluoro- 4-methoxy-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenyl)-N2- (3- fluoropropyl) ethane-1,2- diamine::US10221173, Example 91::US10590132, Example 91::US11046689, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361499&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277079	386400885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714864	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1nccc(OCCNCCCF)c1F |r|	InChI=1S/C24H27F5N4O/c1-15-13-17-16-5-2-3-6-18(16)32-21(17)23(33(15)14-24(27,28)29)22-20(26)19(7-10-31-22)34-12-11-30-9-4-8-25/h2-3,5-7,10,15,23,30,32H,4,8-9,11-14H2,1H3	DEAASBVHFNAUFE-UHFFFAOYSA-N	361500	3-fluoro-N-(2- ((3-fluoro-2- ((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)oxy)ethyl) propan-1-amine::US10221173, Example 92::US10590132, Example 92::US11046689, Example 92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361500&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343566	386400886							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714865	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1nccc(OCCNCCCF)c1Cl |r|	InChI=1S/C24H27ClF4N4O/c1-15-13-17-16-5-2-3-6-18(16)32-21(17)23(33(15)14-24(27,28)29)22-20(25)19(7-10-31-22)34-12-11-30-9-4-8-26/h2-3,5-7,10,15,23,30,32H,4,8-9,11-14H2,1H3	YHADIJUTOZILKY-UHFFFAOYSA-N	361501	N-(2-((3- chloro-2- ((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)oxy)ethyl)- 3- fluoropropan- 1-amine::US10221173, Example 93::US10590132, Example 93::US11046689, Example 93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6600							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361501&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277076	386400887							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714866	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1nccc(NCCNCCCF)c1F |r|	InChI=1S/C24H28F5N5/c1-15-13-17-16-5-2-3-6-18(16)33-21(17)23(34(15)14-24(27,28)29)22-20(26)19(7-10-32-22)31-12-11-30-9-4-8-25/h2-3,5-7,10,15,23,30,33H,4,8-9,11-14H2,1H3,(H,31,32)	IDCGZCFISKMCSA-UHFFFAOYSA-N	361502	N1-(3-fluoro- 2-((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)-N2-(3- fluoropropyl) ethane-1,2- diamine::US10221173, Example 94::US10590132, Example 94::US11046689, Example 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361502	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361502&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343734	386400888							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714867	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1nccc(NCCNCCCF)c1C |r|	InChI=1S/C25H31F4N5/c1-16-14-19-18-6-3-4-7-21(18)33-23(19)24(34(16)15-25(27,28)29)22-17(2)20(8-11-32-22)31-13-12-30-10-5-9-26/h3-4,6-8,11,16,24,30,33H,5,9-10,12-15H2,1-2H3,(H,31,32)	BBPLJPNQLSLHBR-UHFFFAOYSA-N	361503	N1-(3- fluoropropyl)- N2-(3-methyl- 2-((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)ethane-1,2- diamine::US10221173, Example 95::US10590132, Example 95::US11046689, Example 95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361503	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361503&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277118	386400889							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714868	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1nccc(OCCNCCCF)c1C |r|	InChI=1S/C26H33F3N4O2/c1-17-14-20-19-6-3-4-7-21(19)32-24(20)25(33(17)15-26(28,29)16-34)23-18(2)22(8-11-31-23)35-13-12-30-10-5-9-27/h3-4,6-8,11,17,25,30,32,34H,5,9-10,12-16H2,1-2H3	AECNYUDGYFTMJZ-UHFFFAOYSA-N	361504	2,2-difluoro-3- ((1S,3R)-1-(4- (2-((3- fluoropropyl) amino)ethoxy)- 3- methylpyridin- 2-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 96::US10590132, Example 96::US11046689, Example 96	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361504&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263455	386400890							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714869	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1nccc(OCCNCCCF)c1F |r|	InChI=1S/C25H30F4N4O2/c1-16-13-18-17-5-2-3-6-19(17)32-22(18)24(33(16)14-25(28,29)15-34)23-21(27)20(7-10-31-23)35-12-11-30-9-4-8-26/h2-3,5-7,10,16,24,30,32,34H,4,8-9,11-15H2,1H3	NJZWTUKRSGIMHG-UHFFFAOYSA-N	361505	2,2-difluoro-3- ((1S,3R)-1-(3- fluoro-4-(2- ((3- fluoropropyl) amino)ethoxy) pyridin-2-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 97::US10590132, Example 97::US11046689, Example 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 18000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361505&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343748	386400891							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714870	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)F)c1nccc(OCCNCCCF)c1F |r|	InChI=1S/C24H28F4N4O/c1-15-13-17-16-5-2-3-6-18(16)31-22(17)24(32(15)14-20(26)27)23-21(28)19(7-10-30-23)33-12-11-29-9-4-8-25/h2-3,5-7,10,15,20,24,29,31H,4,8-9,11-14H2,1H3	CENZPFDOVSYKKI-UHFFFAOYSA-N	361506	N-(2-((2- ((1S,3R)-2- (2,2- difluoroethyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 3- fluoropyridin- 4- yl)oxy)ethyl)- 3- fluoropropan-1-amine::US10221173, Example 98::US10590132, Example 98::US11046689, Example 98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>32000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361506&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277080	386400892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714871	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)CC1)c1nccc(OCCNCCCF)c1F |r|	InChI=1S/C26H31F3N4O/c1-17-15-19-18-5-2-3-6-20(18)32-23(19)25(33(17)16-26(29)8-9-26)24-22(28)21(7-12-31-24)34-14-13-30-11-4-10-27/h2-3,5-7,12,17,25,30,32H,4,8-11,13-16H2,1H3	HNDBRZGKFVDIIO-UHFFFAOYSA-N	361507	3-fluoro-N-(2- ((3-fluoro-2- ((1S,3R)-2-((1- fluorocyclopropyl) methyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)oxy)ethyl) propan-1-amine::US10221173, Example 99::US10590132, Example 99::US11046689, Example 99	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361507	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361507&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343576	386400893							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714872	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)COC1)c1nccc(OCCNCCCF)c1F |r|	InChI=1S/C26H31F3N4O2/c1-17-13-19-18-5-2-3-6-20(18)32-23(19)25(33(17)14-26(29)15-34-16-26)24-22(28)21(7-10-31-24)35-12-11-30-9-4-8-27/h2-3,5-7,10,17,25,30,32H,4,8-9,11-16H2,1H3	DJLIOXKSBVOKTM-UHFFFAOYSA-N	361508	3-fluoro-N-(2- ((3-fluoro-2- ((1S,3R)-2-((3- fluorooxetan- 3-yl)methyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-4- yl)oxy)ethyl) propan-1-amine::US10221173, Example 100::US10590132, Example 100::US11046689, Example 100	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 19000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361508&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277213	386400894							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714873	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cncc(OCCNCCCF)c1 |r|	InChI=1S/C24H28F4N4O/c1-16-11-20-19-5-2-3-6-21(19)31-22(20)23(32(16)15-24(26,27)28)17-12-18(14-30-13-17)33-10-9-29-8-4-7-25/h2-3,5-6,12-14,16,23,29,31H,4,7-11,15H2,1H3	UCIXEZCTTRFZIE-UHFFFAOYSA-N	361509	3-fluoro-N-(2- ((5-((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-3- yl)oxy)ethyl) propan-1-amine::US10221173, Example 101::US10590132, Example 101::US11046689, Example 101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361509&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277057	386400895							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714874	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1ccnc(OCCNCCCF)c1 |r|	InChI=1S/C24H28F4N4O/c1-16-13-19-18-5-2-3-6-20(18)31-22(19)23(32(16)15-24(26,27)28)17-7-10-30-21(14-17)33-12-11-29-9-4-8-25/h2-3,5-7,10,14,16,23,29,31H,4,8-9,11-13,15H2,1H3	RDIAWWAMKAXZHA-UHFFFAOYSA-N	361510	3-fluoro-N-(2- ((4-((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl) propan-1-amine::US10221173, Example 102::US10590132, Example 102::US11046689, Example 102	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7200							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361510&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343564	386400896							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714875	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1ccnc(OCCNCCCF)c1C |r|	InChI=1S/C26H33F3N4O2/c1-17-14-21-20-6-3-4-7-22(20)32-23(21)24(33(17)15-26(28,29)16-34)19-8-11-31-25(18(19)2)35-13-12-30-10-5-9-27/h3-4,6-8,11,17,24,30,32,34H,5,9-10,12-16H2,1-2H3	SQVCHASDGKDJNV-UHFFFAOYSA-N	361511	2,2-difluoro-3- ((1R,3R)-1-(2- (2-((3- fluoropropyl) amino)ethoxy)- 3- methylpyridin- 4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 103::US10590132, Example 103::US11046689, Example 103	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361511	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361511&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277207	386400897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714876	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1ccnc(OCCNCCCF)c1Cl |r|	InChI=1S/C25H30ClF3N4O2/c1-16-13-19-17-5-2-3-6-20(17)32-22(19)23(33(16)14-25(28,29)15-34)18-7-10-31-24(21(18)26)35-12-11-30-9-4-8-27/h2-3,5-7,10,16,23,30,32,34H,4,8-9,11-15H2,1H3	JAXCPQCVOJTKRR-UHFFFAOYSA-N	361512	3-((1R,3R)-1- (3-chloro-2-(2- ((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan- 1-ol::US10221173, Example 104::US10590132, Example 104::US11046689, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361512&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263162	386400898							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714877	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1nc(OCCNCCCF)ccc1C |r|	InChI=1S/C25H30F4N4O/c1-16-8-9-21(34-13-12-30-11-5-10-26)32-22(16)24-23-19(18-6-3-4-7-20(18)31-23)14-17(2)33(24)15-25(27,28)29/h3-4,6-9,17,24,30-31H,5,10-15H2,1-2H3	GPAKPVKYBBRSFQ-UHFFFAOYSA-N	361513	3-fluoro-N-(2- ((5-methyl-6- ((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl) propan-1-amine::US10221173, Example 105::US10590132, Example 105::US11046689, Example 105	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3500							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361513&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277206	386400899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714878	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1ccnc(OCCNCCCF)c1C |r|	InChI=1S/C25H30F4N4O/c1-16-14-20-19-6-3-4-7-21(19)32-22(20)23(33(16)15-25(27,28)29)18-8-11-31-24(17(18)2)34-13-12-30-10-5-9-26/h3-4,6-8,11,16,23,30,32H,5,9-10,12-15H2,1-2H3	QKFUYFJFULHFGA-UHFFFAOYSA-N	361514	3-fluoro-N-(2- ((3-methyl-4- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl) propan-1-amine::US10221173, Example 106::US10590132, Example 106::US11046689, Example 106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361514&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343754	386400900							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714879	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)cnc(OCCNCCCF)c1F |r|	InChI=1S/C24H26F6N4O/c1-14-11-16-15-5-2-3-6-18(15)33-21(16)22(34(14)13-24(28,29)30)19-17(26)12-32-23(20(19)27)35-10-9-31-8-4-7-25/h2-3,5-6,12,14,22,31,33H,4,7-11,13H2,1H3	FGJFWVZUSZMTOU-UHFFFAOYSA-N	361515	N-(2-((3,5- difluoro-4- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl)- 3- fluoropropan- 1-amine::US10221173, Example 107::US10590132, Example 107::US11046689, Example 107	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361515&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277071	386400901							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714880	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)CC1)c1c(F)cnc(OCCNCCCF)c1F |r|	InChI=1S/C26H30F4N4O/c1-16-13-18-17-5-2-3-6-20(17)33-23(18)24(34(16)15-26(30)7-8-26)21-19(28)14-32-25(22(21)29)35-12-11-31-10-4-9-27/h2-3,5-6,14,16,24,31,33H,4,7-13,15H2,1H3	CISZCLKQAXVPAL-UHFFFAOYSA-N	361516	N-(2-((3,5- difluoro-4- ((1R,3R)-2-((1- fluorocyclopropyl) methyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl)- 3- fluoropropan- 1-amine::US10221173, Example 108::US10590132, Example 108::US11046689, Example 108	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361516&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343789	386400902							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714881	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1C |r|	InChI=1S/C26H32F4N4O2/c1-16-12-19-18-6-3-4-7-21(18)33-23(19)24(34(16)14-26(29,30)15-35)22-17(2)25(32-13-20(22)28)36-11-10-31-9-5-8-27/h3-4,6-7,13,16,24,31,33,35H,5,8-12,14-15H2,1-2H3	SXZDGPTXQLHTHB-UHFFFAOYSA-N	361518	2,2-difluoro-3- ((1R,3R)-1-(5- fluoro-2-(2- ((3- fluoropropyl) amino)ethoxy)- 3- methylpyridin- 4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 110::US10590132, Example 110::US11046689, Example 110	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2800							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361518&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277074	386400904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714882	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1Cl |r|	InChI=1S/C25H29ClF4N4O2/c1-15-11-17-16-5-2-3-6-19(16)33-22(17)23(34(15)13-25(29,30)14-35)20-18(28)12-32-24(21(20)26)36-10-9-31-8-4-7-27/h2-3,5-6,12,15,23,31,33,35H,4,7-11,13-14H2,1H3	NXEDZKAQYWQSQZ-UHFFFAOYSA-N	361519	3-((1R,3R)-1- (3-chloro-5- fluoro-2-(2- ((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- difluoropropan- 1-ol::US10221173, Example 111::US10590132, Example 111::US11046689, Example 111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5100							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361519&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263168	386400905							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714883	COc1nnc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r|	InChI=1S/C24H29F4N5O2/c1-15-12-17-16-6-3-4-7-19(16)30-21(17)22(33(15)14-24(26,27)28)18-13-20(31-32-23(18)34-2)35-11-10-29-9-5-8-25/h3-4,6-7,13,15,22,29-30H,5,8-12,14H2,1-2H3	ZYVTYEUBKQMHOG-UHFFFAOYSA-N	361520	3-fluoro-N-(2- ((6-methoxy-5- ((1R,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridazin-3- yl)oxy)ethyl) propan-1-amine::US10221173, Example 112::US10590132, Example 112::US11046689, Example 112	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 19000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361520	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361520&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277051	386400906							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714884	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1ncnc(OCCNCCCF)c1C |r|	InChI=1S/C24H29F4N5O/c1-15-12-18-17-6-3-4-7-19(17)32-21(18)22(33(15)13-24(26,27)28)20-16(2)23(31-14-30-20)34-11-10-29-9-5-8-25/h3-4,6-7,14-15,22,29,32H,5,8-13H2,1-2H3	IELFPOQNITXXKS-UHFFFAOYSA-N	361522	3-fluoro-N-(2- ((5-methyl-6- ((1S,3R)-3- methyl-2- (2,2,2- trifluoroethyl)- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyrimidin- 4- yl)oxy)ethyl) propan-1-amine::US10221173, Example 114::US10590132, Example 114::US11046689, Example 114	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5900							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361522	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361522&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277052	386400908							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714885	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1ncnc(OCCNCCCF)c1C |r|	InChI=1S/C25H32F3N5O2/c1-16-12-19-18-6-3-4-7-20(18)32-22(19)23(33(16)13-25(27,28)14-34)21-17(2)24(31-15-30-21)35-11-10-29-9-5-8-26/h3-4,6-7,15-16,23,29,32,34H,5,8-14H2,1-2H3	FYGHYLSMAUZDLK-UHFFFAOYSA-N	361523	2,2-difluoro-3- ((1S,3R)-1-(6- (2-((3- fluoropropyl) amino)ethoxy)- 5- methylpyrimidin- 4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10221173, Example 115::US10590132, Example 115::US11046689, Example 115	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361523&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263508	386400909							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714886	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C)C(O)=O |r|	InChI=1S/C28H35F2N3O3/c1-17(28(34)35)16-33-18(2)15-21-20-7-4-5-8-23(20)32-26(21)27(33)25-19(3)24(10-9-22(25)30)36-14-13-31-12-6-11-29/h4-5,7-10,17-18,27,31-32H,6,11-16H2,1-3H3,(H,34,35)	KNSMOAXIFSMQRE-UHFFFAOYSA-N	361525	(R)-3-((1R,3R)-1-(6-fluoro-3-(2-((3-fluoropropyl)amino)ethoxy)-2-methylphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 117::US10590132, Example 117::US11046689, Example 117	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361525&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343822	386400911							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714887	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(C)(C)C(O)=O)c1c(F)ccc(OCCNCCCF)c1C |r|	InChI=1S/C29H37F2N3O3/c1-18-16-21-20-8-5-6-9-23(20)33-26(21)27(34(18)17-29(3,4)28(35)36)25-19(2)24(11-10-22(25)31)37-15-14-32-13-7-12-30/h5-6,8-11,18,27,32-33H,7,12-17H2,1-4H3,(H,35,36)	USIFNCZDZPSPJZ-UHFFFAOYSA-N	361527	3-((1R,3R)-1- (6-fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy)- 2- methylphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2,2- dimethyl- propanoic acid::US10221173, Example 119::US10590132, Example 119::US11046689, Example 119	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361527&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135263488	386400913							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714888	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccc(F)cc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C)C(O)=O |r|	InChI=1S/C28H34F3N3O3/c1-16(28(35)36)15-34-17(2)13-21-20-14-19(30)5-7-23(20)33-26(21)27(34)25-18(3)24(8-6-22(25)31)37-12-11-32-10-4-9-29/h5-8,14,16-17,27,32-33H,4,9-13,15H2,1-3H3,(H,35,36)	JOFYCYZGTXIWEJ-UHFFFAOYSA-N	361529	(R)-3-((1R,3R)-6-fluoro-1-(6-fluoro-3-(2-((3-fluoropropyl)amino)ethoxy)-2-methylphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 121::US10590132, Example 121::US11046689, Example 121	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361529&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277023	386400915							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714889	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCC(F)F)c1C)C(O)=O |r|	InChI=1S/C28H34F3N3O3/c1-16(28(35)36)15-34-17(2)14-20-19-6-4-5-7-22(19)33-26(20)27(34)25-18(3)23(9-8-21(25)29)37-13-12-32-11-10-24(30)31/h4-9,16-17,24,27,32-33H,10-15H2,1-3H3,(H,35,36)	BTJWAAQFFCCLEV-UHFFFAOYSA-N	361531	(R)-3- ((1R,3R)-1-(3- (2-((3,3- difluoropropyl) amino)ethoxy)- 6-fluoro-2- methylphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 123::US10590132, Example 123::US11046689, Example 123	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361531&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277113	386400917							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714890	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C(F)F)C(O)=O |r|	InChI=1S/C28H33F4N3O3/c1-16(28(36)37)15-35-17(2)14-19-18-6-3-4-7-21(18)34-25(19)26(35)23-20(30)8-9-22(24(23)27(31)32)38-13-12-33-11-5-10-29/h3-4,6-9,16-17,26-27,33-34H,5,10-15H2,1-2H3,(H,36,37)	SHBYLUMKVZHSKT-UHFFFAOYSA-N	361533	(S)-3-((1R,3R)- 1-(2- (difluoromethyl)- 6-fluoro-3- (2-((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 125::US10590132, Example 125::US11046689, Example 125	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361533&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343755	386400919							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714891	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCNCCCF)c1C)C(O)=O |r|	InChI=1S/C27H34F2N4O3/c1-16(27(34)35)15-33-17(2)13-20-19-7-4-5-8-22(19)32-24(20)25(33)23-18(3)26(31-14-21(23)29)36-12-11-30-10-6-9-28/h4-5,7-8,14,16-17,25,30,32H,6,9-13,15H2,1-3H3,(H,34,35)	JMHAEPDWKOSCPH-UHFFFAOYSA-N	361534	(S)-3-((1R,3R)-1-(5-fluoro-2-(2-((3-fluoropropyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 126::US10590132, Example 126::US11046689, Example 126	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361534&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343806	386400920							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714892	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(Cl)ccc(OCCNCCCF)c1Cl)C(O)=O |r|	InChI=1S/C27H32Cl2FN3O3/c1-16(27(34)35)15-33-17(2)14-19-18-6-3-4-7-21(18)32-25(19)26(33)23-20(28)8-9-22(24(23)29)36-13-12-31-11-5-10-30/h3-4,6-9,16-17,26,31-32H,5,10-15H2,1-2H3,(H,34,35)	BVXHNEYXSTUIFZ-UHFFFAOYSA-N	361536	(S)-3-((1R,3R)- 1-(2,6- dichloro-3-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 128::US10590132, Example 128::US11046689, Example 128	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361536&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277067	386400922							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714893	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1ccnc(OCCNCCCF)c1C)C(O)=O |r|	InChI=1S/C27H35FN4O3/c1-17(27(33)34)16-32-18(2)15-22-21-7-4-5-8-23(21)31-24(22)25(32)20-9-12-30-26(19(20)3)35-14-13-29-11-6-10-28/h4-5,7-9,12,17-18,25,29,31H,6,10-11,13-16H2,1-3H3,(H,33,34)	CLEHWPAJGUZRJR-UHFFFAOYSA-N	361540	(S)-3-((1R,3R)- 1-(2-(2-((3- fluoropropyl) amino)ethoxy)- 3- methylpyridin- 4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 132::US10590132, Example 132::US11046689, Example 132	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361540	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361540&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343786	386400925							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714894	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCNCCCF)c1Cl)C(O)=O |r|	InChI=1S/C26H31ClF2N4O3/c1-15(26(34)35)14-33-16(2)12-18-17-6-3-4-7-20(17)32-23(18)24(33)21-19(29)13-31-25(22(21)27)36-11-10-30-9-5-8-28/h3-4,6-7,13,15-16,24,30,32H,5,8-12,14H2,1-2H3,(H,34,35)	HJOWIZWEMFJVRX-UHFFFAOYSA-N	361541	(S)-3-((1R,3R)- 1-(3-chloro-5- fluoro-2-(2- ((3- fluoropropyl) amino)ethoxy) pyridin-4-yl)-3- methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 133::US10590132, Example 133::US11046689, Example 133	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361541	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361541&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343727	386400926							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714895	C[C@@H](CN1[C@@H](Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C)C(F)F)C(O)=O |r|	InChI=1S/C28H33F4N3O3/c1-16(28(36)37)15-35-22(27(31)32)14-19-18-6-3-4-7-21(18)34-25(19)26(35)24-17(2)23(9-8-20(24)30)38-13-12-33-11-5-10-29/h3-4,6-9,16,22,26-27,33-34H,5,10-15H2,1-2H3,(H,36,37)	WHTFAERDNGSMFX-UHFFFAOYSA-N	361545	(S)-3-((1R,3S)- 3- (difluoromethyl)- 1-(6-fluoro- 3-(2-((3- fluoropropyl) amino)ethoxy)- 2- methylphenyl)- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 137::US10590132, Example 137::US11046689, Example 137	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361545	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361545&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343593	386400930							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714896	C[C@@H](CN1[C@@H](Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1Cl)C(F)F)C(O)=O |r|	InChI=1S/C27H30ClF4N3O3/c1-15(27(36)37)14-35-20(26(31)32)13-17-16-5-2-3-6-19(16)34-24(17)25(35)22-18(30)7-8-21(23(22)28)38-12-11-33-10-4-9-29/h2-3,5-8,15,20,25-26,33-34H,4,9-14H2,1H3,(H,36,37)	JKJKFIRFFROVTG-UHFFFAOYSA-N	361546	(S)-3-((1R,3S)- 1-(2-chloro-6- fluoro-3-(2- ((3- fluoropropyl) amino)ethoxy) phenyl)-3- (difluoromethyl)- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 138::US10590132, Example 138::US11046689, Example 138	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361546&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343735	386400931							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714897	C[C@@H](CN1[C@@H](Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCNCCCF)c1C)C(F)(F)F)C(O)=O |r|	InChI=1S/C28H32F5N3O3/c1-16(27(37)38)15-36-23(28(31,32)33)14-19-18-6-3-4-7-21(18)35-25(19)26(36)24-17(2)22(9-8-20(24)30)39-13-12-34-11-5-10-29/h3-4,6-9,16,23,26,34-35H,5,10-15H2,1-2H3,(H,37,38)	WJDRCCIYQLMRTE-UHFFFAOYSA-N	361548	(S)-3-((1R,3S)- 1-(6-fluoro-3- (2-((3- fluoropropyl) amino)ethoxy)- 2- methylphenyl)- 3- (trifluoromethyl)- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 140::US10590132, Example 140::US11046689, Example 140	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361548&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343544	386400933							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714898	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCN(C)CCCF)c1C)C(O)=O |r|	InChI=1S/C29H37F2N3O3/c1-18(29(35)36)17-34-19(2)16-22-21-8-5-6-9-24(21)32-27(22)28(34)26-20(3)25(11-10-23(26)31)37-15-14-33(4)13-7-12-30/h5-6,8-11,18-19,28,32H,7,12-17H2,1-4H3,(H,35,36)	OUWDZJIZWQEYKX-UHFFFAOYSA-N	361551	(S)-3-((1R,3R)-1-(6-fluoro-3-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-2-methylphenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 150::US10221173, Example 143::US10590132, Example 143::US11046689, Example 150	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361551&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343702	386400936							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714899	C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCN(C)CCCF)c1C)C(O)=O |r|	InChI=1S/C28H36F2N4O3/c1-17(28(35)36)16-34-18(2)14-21-20-8-5-6-9-23(20)32-25(21)26(34)24-19(3)27(31-15-22(24)30)37-13-12-33(4)11-7-10-29/h5-6,8-9,15,17-18,26,32H,7,10-14,16H2,1-4H3,(H,35,36)	WXZYOKABAPSHMB-UHFFFAOYSA-N	361553	(S)-3-((1R,3R)-1-(5-fluoro-2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 145::US10590132, Example 145::US11046689, Example 145	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361553&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343819	386400938							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714900	C[C@@H](CN1[C@@H](Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCN(C)CCCF)c1C)C(F)(F)F)C(O)=O |r|	InChI=1S/C29H34F5N3O3/c1-17(28(38)39)16-37-24(29(32,33)34)15-20-19-7-4-5-8-22(19)35-26(20)27(37)25-18(2)23(10-9-21(25)31)40-14-13-36(3)12-6-11-30/h4-5,7-10,17,24,27,35H,6,11-16H2,1-3H3,(H,38,39)	JFIIYWRSZXNVNN-UHFFFAOYSA-N	361557	(S)-3-((1R,3S)- 1-(6-fluoro-3- (2-((3- fluoropropyl) (methyl)amino) ethoxy)-2- methylphenyl)- 3- (trifluoromethyl)- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 149::US10590132, Example 149::US11046689, Example 149	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361557&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343778	386400942							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714901	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCN(C)CCCF)c1C)C(O)=O |r|	InChI=1S/C29H37F2N3O3/c1-18(29(35)36)17-34-19(2)16-22-21-8-5-6-9-24(21)32-27(22)28(34)26-20(3)25(11-10-23(26)31)37-15-14-33(4)13-7-12-30/h5-6,8-11,18-19,28,32H,7,12-17H2,1-4H3,(H,35,36)	OUWDZJIZWQEYKX-UHFFFAOYSA-N	361559	(R)-3- ((1R,3R)-1-(6- fluoro-3-(2- ((3- fluoropropyl) (methyl)amino) ethoxy)-2- methylphenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 151::US11046689, Example 151	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361559	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361559&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277081	386400943							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714902	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCN(C)CCCF)c1C)C(O)=O |r|	InChI=1S/C28H36F2N4O3/c1-17(28(35)36)16-34-18(2)14-21-20-8-5-6-9-23(20)32-25(21)26(34)24-19(3)27(31-15-22(24)30)37-13-12-33(4)11-7-10-29/h5-6,8-9,15,17-18,26,32H,7,10-14,16H2,1-4H3,(H,35,36)	WXZYOKABAPSHMB-UHFFFAOYSA-N	361560	US10221173, Example 153::(R)-3-((1R,3R)-1-(5-fluoro-2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 152::US10590132, Example 152::US11046689, Example 152	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361560	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361560&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135343705	386400944							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714903	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)COC1)c1c(F)ccc(OCCN(C)CCCF)c1F |r|	InChI=1S/C28H33F4N3O2/c1-18-14-20-19-6-3-4-7-22(19)33-26(20)27(35(18)15-28(32)16-36-17-28)24-21(30)8-9-23(25(24)31)37-13-12-34(2)11-5-10-29/h3-4,6-9,18,27,33H,5,10-17H2,1-2H3	OJGOUNHODAIUMQ-UHFFFAOYSA-N	361562	N-(2-(2,4- difluoro-3- ((1R,3R)-2-((3- fluorooxetan- 3-yl)methyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)-3-fluoro-N- methylpropan- 1-amine::US10221173, Example 154::US10590132, Example 154::US11046689, Example 154	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4300							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361562	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361562&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277083	386400945							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714904	C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CCC(O)=O)c1c(F)cnc(OCCN(C)CCCF)c1C |r|	InChI=1S/C27H33F3N4O3/c1-16-13-20-19-14-18(29)5-6-22(19)32-25(20)26(34(16)10-7-23(35)36)24-17(2)27(31-15-21(24)30)37-12-11-33(3)9-4-8-28/h5-6,14-16,26,32H,4,7-13H2,1-3H3,(H,35,36)	IFPIYUWYLHTNBQ-UHFFFAOYSA-N	361564	Preparation of 3-((1R,3R)-6-fluoro-1-(5-fluoro-2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)propanoic acid::US10221173, Example 156::US10590132, Example 156::US11046689, Example 156	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361564&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277037	386400947							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714905	C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CCC(O)=O)c1c(F)cnc(OCCN(C)CCCF)c1C |r|	InChI=1S/C27H34F2N4O3/c1-17-15-20-19-7-4-5-8-22(19)31-25(20)26(33(17)12-9-23(34)35)24-18(2)27(30-16-21(24)29)36-14-13-32(3)11-6-10-28/h4-5,7-8,16-17,26,31H,6,9-15H2,1-3H3,(H,34,35)	PORUFPRURWGFMV-UHFFFAOYSA-N	361565	Preparation of 3-((1R,3R)-1-(5-fluoro-2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)propanoic acid::US10221173, Example 157::US10590132, Example 157::US11046689, Example 157	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361565	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361565&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277009	386400948							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714906	CC(CC(O)=O)N1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCN(C)CCCF)c1C |r|	InChI=1S/C28H36F2N4O3/c1-17-14-21-20-8-5-6-9-23(20)32-26(21)27(34(17)18(2)15-24(35)36)25-19(3)28(31-16-22(25)30)37-13-12-33(4)11-7-10-29/h5-6,8-9,16-18,27,32H,7,10-15H2,1-4H3,(H,35,36)	NJVNBIIYSTWWOU-UHFFFAOYSA-N	361566	Preparation of 3-((1R,3R)-1-(5-fluoro-2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)butanoic acid::US10221173, Example 159::US10221173, Example 158::US10590132, Example 159::US11046689, Example 159	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361566&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277047	386400949							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714907	CC(CC(O)=O)N1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCN(C)CCCF)c1C |r|	InChI=1S/C28H36F2N4O3/c1-17-14-21-20-8-5-6-9-23(20)32-26(21)27(34(17)18(2)15-24(35)36)25-19(3)28(31-16-22(25)30)37-13-12-33(4)11-7-10-29/h5-6,8-9,16-18,27,32H,7,10-15H2,1-4H3,(H,35,36)	NJVNBIIYSTWWOU-UHFFFAOYSA-N	361566	Preparation of 3-((1R,3R)-1-(5-fluoro-2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)butanoic acid::US10221173, Example 159::US10221173, Example 158::US10590132, Example 159::US11046689, Example 159	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361566&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277047	386400949							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714908	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1ccnc(OCCN(C)CCCF)c1C)C(O)=O |r|	InChI=1S/C28H37FN4O3/c1-18(28(34)35)17-33-19(2)16-23-22-8-5-6-9-24(22)31-25(23)26(33)21-10-12-30-27(20(21)3)36-15-14-32(4)13-7-11-29/h5-6,8-10,12,18-19,26,31H,7,11,13-17H2,1-4H3,(H,34,35)	UYQMGGVHIFKJLM-UHFFFAOYSA-N	361569	Preparation of (R)-3-((1R,3R)-1-(2-(2-((3-fluoropropyl)(methyl)amino)ethoxy)-3-methylpyridin-4-yl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 161::US10590132, Example 161::US11046689, Example 161	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361569	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361569&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135277182	386400951							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
714909	C[C@H](CN1[C@H](C)Cc2c([nH]c3ccc(F)cc23)[C@H]1c1c(F)ccc(OCCNCCC(F)F)c1C)C(O)=O |r|	InChI=1S/C28H33F4N3O3/c1-15(28(36)37)14-35-16(2)12-20-19-13-18(29)4-6-22(19)34-26(20)27(35)25-17(3)23(7-5-21(25)30)38-11-10-33-9-8-24(31)32/h4-7,13,15-16,24,27,33-34H,8-12,14H2,1-3H3,(H,36,37)	SMUDZEUPOGINMX-UHFFFAOYSA-N	361570	Preparation of (R)-3-((1R,3R)-1-(3-(2-((3,3-difluoropropyl)amino)ethoxy)-6-fluoro-2-methylphenyl)-6-fluoro-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2-methylpropanoic acid::US10221173, Example 162::US10590132, Example 162::US11046689, Example 162	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>40000							US Patent		10.7270/Q2HD7XZS		aid1797835	US10221173	Nissink, JW; Scott, JS; Moss, TA; Hughes, SJ; Barlaam, BC; Yang, B	3/5/2019	10/27/2019	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361570	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361570&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			135276991	386400952							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715393	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US9968610, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715395	FC(F)(F)c1ccc(CCN2CCC(Nc3ncnc4[nH]ncc34)C(F)(F)C2)cc1	InChI=1S/C19H19F5N6/c20-18(21)10-30(7-5-12-1-3-13(4-2-12)19(22,23)24)8-6-15(18)28-16-14-9-27-29-17(14)26-11-25-16/h1-4,9,11,15H,5-8,10H2,(H2,25,26,27,28,29)	JZWSSGCJYKYCCT-UHFFFAOYSA-N	361982	US10221182, Compound E2-1.5::US10221182, Compound E1-1.5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9800							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361982&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122445221	386401348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715397	FC(F)(F)c1ccc(CCN2CCC(Nc3ncnc4[nH]ncc34)C(F)(F)C2)cc1	InChI=1S/C19H19F5N6/c20-18(21)10-30(7-5-12-1-3-13(4-2-12)19(22,23)24)8-6-15(18)28-16-14-9-27-29-17(14)26-11-25-16/h1-4,9,11,15H,5-8,10H2,(H2,25,26,27,28,29)	JZWSSGCJYKYCCT-UHFFFAOYSA-N	361982	US10221182, Compound E2-1.5::US10221182, Compound E1-1.5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7600							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361982	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361982&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122445221	386401348							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715399	FC1(F)CN(CCc2ccccc2)CCC1Nc1ncnc2[nH]ncc12	InChI=1S/C18H20F2N6/c19-18(20)11-26(8-6-13-4-2-1-3-5-13)9-7-15(18)24-16-14-10-23-25-17(14)22-12-21-16/h1-5,10,12,15H,6-9,11H2,(H2,21,22,23,24,25)	WHBAEJDKYDGMTF-UHFFFAOYSA-N	361984	US10221182, Compound E1-1.12::US10221182, Compound C-1.1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 71000							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361984	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361984&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122445252	386401349							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715407	Fc1ccc(CCN2CCC(Nc3ncnc4[nH]ncc34)C(F)(F)C2)cc1	InChI=1S/C18H19F3N6/c19-13-3-1-12(2-4-13)5-7-27-8-6-15(18(20,21)10-27)25-16-14-9-24-26-17(14)23-11-22-16/h1-4,9,11,15H,5-8,10H2,(H2,22,23,24,25,26)	HRAWCZZERIVUGM-UHFFFAOYSA-N	361991	US10221182, Compound C-1.2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16300							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361991	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361991&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122445231	386401355							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715409	Cc1ccc(CCN2CCC(Nc3ncnc4[nH]ncc34)C(F)(F)C2)cc1	InChI=1S/C19H22F2N6/c1-13-2-4-14(5-3-13)6-8-27-9-7-16(19(20,21)11-27)25-17-15-10-24-26-18(15)23-12-22-17/h2-5,10,12,16H,6-9,11H2,1H3,(H2,22,23,24,25,26)	UUWRLGUXZAUHPY-UHFFFAOYSA-N	361992	US10221182, Compound E2-1.4::US10221182, Compound E1-1.4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21900							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361992&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122445179	386401356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715411	Cc1ccc(CCN2CCC(Nc3ncnc4[nH]ncc34)C(F)(F)C2)cc1	InChI=1S/C19H22F2N6/c1-13-2-4-14(5-3-13)6-8-27-9-7-16(19(20,21)11-27)25-17-15-10-24-26-18(15)23-12-22-17/h2-5,10,12,16H,6-9,11H2,1H3,(H2,22,23,24,25,26)	UUWRLGUXZAUHPY-UHFFFAOYSA-N	361992	US10221182, Compound E2-1.4::US10221182, Compound E1-1.4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15500							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361992	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361992&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122445179	386401356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
715418	FC(F)c1ccc(CCN2CCC(Nc3ncnc4[nH]ncc34)C(F)(F)C2)cc1	InChI=1S/C19H20F4N6/c20-16(21)13-3-1-12(2-4-13)5-7-29-8-6-15(19(22,23)10-29)27-17-14-9-26-28-18(14)25-11-24-17/h1-4,9,11,15-16H,5-8,10H2,(H2,24,25,26,27,28)	SMYMUFLLNCPUGB-UHFFFAOYSA-N	361999	US10221182, Compound E2-1.6::US10221182, Compound E1-1.6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3500							US Patent		10.7270/Q2VQ34ZZ		aid1797863	US10221182	Shapiro, G	3/5/2019	10/27/2019	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=361999	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=361999&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			122482224	386401362							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750082	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H21F3N2O2/c21-14-2-1-3-15(10-14)27-19-12-17(23)16(22)11-18(19)25-7-4-20(5-8-25)13-24-6-9-26-20/h1-3,10-12,24H,4-9,13H2	GQORDSCTOHJVGL-UHFFFAOYSA-N	375623	US9908897, Example 1::US9908897, Example 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375623	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375623&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960479	404344654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750092	Fc1cccc(Oc2ccccc2N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H23FN2O2/c21-16-4-3-5-17(14-16)25-19-7-2-1-6-18(19)23-11-8-20(9-12-23)15-22-10-13-24-20/h1-7,14,22H,8-13,15H2	AENFZRBXHCJOOC-UHFFFAOYSA-N	375626	US9908897, Example 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1585							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375626	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375626&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960445	404344656							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750096	N#Cc1ccc(Oc2ccccc2)c(c1)N1CCC2(CC1)CNCCO2	InChI=1S/C21H23N3O2/c22-15-17-6-7-20(26-18-4-2-1-3-5-18)19(14-17)24-11-8-21(9-12-24)16-23-10-13-25-21/h1-7,14,23H,8-13,16H2	SUAONMDAKPJEMZ-UHFFFAOYSA-N	375627	US9908897, Example 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 631							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375627	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375627&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960491	404344657							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750103	Fc1cccc(Oc2cccc(c2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H23FN2O2/c21-16-3-1-5-18(13-16)25-19-6-2-4-17(14-19)23-10-7-20(8-11-23)15-22-9-12-24-20/h1-6,13-14,22H,7-12,15H2	IMNSKYRLCRDJKU-UHFFFAOYSA-N	375629	US9908897, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1585							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375629	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375629&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960465	404344659							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750107	Fc1cccc(Oc2cc(F)cc(c2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H22F2N2O2/c21-15-2-1-3-18(11-15)26-19-12-16(22)10-17(13-19)24-7-4-20(5-8-24)14-23-6-9-25-20/h1-3,10-13,23H,4-9,14H2	OZUKNWTZRJTZAM-UHFFFAOYSA-N	375631	US9908897, Example 8::US9908897, Example 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 501							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960428	404344661							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750114	Fc1cccc(Oc2ccc(F)c(c2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H22F2N2O2/c21-15-2-1-3-16(12-15)26-17-4-5-18(22)19(13-17)24-9-6-20(7-10-24)14-23-8-11-25-20/h1-5,12-13,23H,6-11,14H2	XPDRLYDNKSWESD-UHFFFAOYSA-N	375633	US9908897, Example 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2512							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375633	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375633&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960391	404344662							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750118	Fc1cccc(Oc2cc(ccc2F)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H22F2N2O2/c21-15-2-1-3-17(12-15)26-19-13-16(4-5-18(19)22)24-9-6-20(7-10-24)14-23-8-11-25-20/h1-5,12-13,23H,6-11,14H2	AUZMCSDTNJIOIN-UHFFFAOYSA-N	375634	US9908897, Example 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 316							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375634	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375634&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960477	404344663							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750125	Fc1cccc(Oc2cc(F)c(F)c(c2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H21F3N2O2/c21-14-2-1-3-15(10-14)27-16-11-17(22)19(23)18(12-16)25-7-4-20(5-8-25)13-24-6-9-26-20/h1-3,10-12,24H,4-9,13H2	NDUZYNZHAAONON-UHFFFAOYSA-N	375636	US9908897, Example 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2512							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375636&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960511	404344665							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750132	Fc1c(Oc2ccccc2)cccc1N1CCC2(CC1)CNCCO2	InChI=1S/C20H23FN2O2/c21-19-17(7-4-8-18(19)25-16-5-2-1-3-6-16)23-12-9-20(10-13-23)15-22-11-14-24-20/h1-8,22H,9-15H2	UQJOXFKJBZTQRN-UHFFFAOYSA-N	375639	US9908897, Example 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3981							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375639	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375639&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960586	404344668							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750136	Fc1cccc(Oc2cccc(N3CCC4(CC3)CNCCO4)c2F)c1	InChI=1S/C20H22F2N2O2/c21-15-3-1-4-16(13-15)26-18-6-2-5-17(19(18)22)24-10-7-20(8-11-24)14-23-9-12-25-20/h1-6,13,23H,7-12,14H2	IFKASTTVCISIPF-UHFFFAOYSA-N	375640	US9908897, Example 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3981							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375640	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375640&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960372	404344669							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750140	Fc1cccc(Oc2cc(F)cc(N3CCC4(CC3)CNCCO4)c2F)c1	InChI=1S/C20H21F3N2O2/c21-14-2-1-3-16(10-14)27-18-12-15(22)11-17(19(18)23)25-7-4-20(5-8-25)13-24-6-9-26-20/h1-3,10-12,24H,4-9,13H2	UPTRBXKTOJZNAB-UHFFFAOYSA-N	375641	US9908897, Example 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3981							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375641	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375641&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960480	404344670							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750147	N#Cc1cc(Oc2ccccc2)cc(c1)N1CCC2(CC1)CNCCO2	InChI=1S/C21H23N3O2/c22-15-17-12-18(14-20(13-17)26-19-4-2-1-3-5-19)24-9-6-21(7-10-24)16-23-8-11-25-21/h1-5,12-14,23H,6-11,16H2	NNDGBQCSFXUKBN-UHFFFAOYSA-N	375644	US9908897, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 794							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375644	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375644&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960430	404344673							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750169	Fc1cccc(Oc2cc(cc(n2)N2CCC3(CC2)CNCCO3)C(F)(F)F)c1	InChI=1S/C20H21F4N3O2/c21-15-2-1-3-16(12-15)29-18-11-14(20(22,23)24)10-17(26-18)27-7-4-19(5-8-27)13-25-6-9-28-19/h1-3,10-12,25H,4-9,13H2	AQKXRQBPFRGBIM-UHFFFAOYSA-N	375651	US9908897, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1259							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375651	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375651&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960379	404344680							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750182	Fc1cccc(Oc2cncc(n2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C18H21FN4O2/c19-14-2-1-3-15(10-14)25-17-12-21-11-16(22-17)23-7-4-18(5-8-23)13-20-6-9-24-18/h1-3,10-12,20H,4-9,13H2	SOMCZPYVBBJNGE-UHFFFAOYSA-N	375657	US9908897, Example 41	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1259							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375657	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375657&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960468	404344686							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750186	Fc1cccc(Oc2ccnc(n2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C18H21FN4O2/c19-14-2-1-3-15(12-14)25-16-4-7-21-17(22-16)23-9-5-18(6-10-23)13-20-8-11-24-18/h1-4,7,12,20H,5-6,8-11,13H2	TYLUAGXHVPXCPL-UHFFFAOYSA-N	375658	US9908897, Example 42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 398							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375658	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375658&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960462	404344687							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750190	Cc1cc(Oc2ccccc2)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C19H24N4O2/c1-15-13-17(25-16-5-3-2-4-6-16)22-18(21-15)23-10-7-19(8-11-23)14-20-9-12-24-19/h2-6,13,20H,7-12,14H2,1H3	NLLQBYDAGGXFCP-UHFFFAOYSA-N	375659	US9908897, Example 43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375659	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375659&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960378	404344688							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750194	Cc1cc(Oc2cccc(F)c2)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C19H23FN4O2/c1-14-11-17(26-16-4-2-3-15(20)12-16)23-18(22-14)24-8-5-19(6-9-24)13-21-7-10-25-19/h2-4,11-12,21H,5-10,13H2,1H3	AMRJKHDSDIXQIV-UHFFFAOYSA-N	375660	US9908897, Example 44	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375660	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375660&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960402	404344689							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750198	Cc1cccc(Oc2cc(C)nc(n2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H26N4O2/c1-15-4-3-5-17(12-15)26-18-13-16(2)22-19(23-18)24-9-6-20(7-10-24)14-21-8-11-25-20/h3-5,12-13,21H,6-11,14H2,1-2H3	GCNZXETZIBQOCG-UHFFFAOYSA-N	375661	US9908897, Example 45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375661	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375661&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960543	404344690							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750202	Cc1cc(Oc2cccc(c2)C#N)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C20H23N5O2/c1-15-11-18(27-17-4-2-3-16(12-17)13-21)24-19(23-15)25-8-5-20(6-9-25)14-22-7-10-26-20/h2-4,11-12,22H,5-10,14H2,1H3	OSYDLANVDZCPRE-UHFFFAOYSA-N	375662	US9908897, Example 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 251							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375662&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960489	404344691							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750209	Cc1cc(Oc2cccc(c2)C(F)(F)F)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C20H23F3N4O2/c1-14-11-17(29-16-4-2-3-15(12-16)20(21,22)23)26-18(25-14)27-8-5-19(6-9-27)13-24-7-10-28-19/h2-4,11-12,24H,5-10,13H2,1H3	GFSLVODSBSASAE-UHFFFAOYSA-N	375664	US9908897, Example 48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2512							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375664	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375664&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960452	404344693							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750213	COc1cccc(Oc2cc(C)nc(n2)N2CCC3(CC2)CNCCO3)c1	InChI=1S/C20H26N4O3/c1-15-12-18(27-17-5-3-4-16(13-17)25-2)23-19(22-15)24-9-6-20(7-10-24)14-21-8-11-26-20/h3-5,12-13,21H,6-11,14H2,1-2H3	WIPVJHVRGPHILG-UHFFFAOYSA-N	375668	US9908897, Example 49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3162							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960493	404344696							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750232	FC(F)(F)c1cc(Oc2ccccc2)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C19H21F3N4O2/c20-19(21,22)15-12-16(28-14-4-2-1-3-5-14)25-17(24-15)26-9-6-18(7-10-26)13-23-8-11-27-18/h1-5,12,23H,6-11,13H2	WGUWYPRRZSZZLF-UHFFFAOYSA-N	375674	US9908897, Example 55	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375674	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375674&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960376	404344702							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750239	Fc1ccccc1Oc1cc(nc(n1)N1CCC2(CC1)CNCCO2)C(F)(F)F	InChI=1S/C19H20F4N4O2/c20-13-3-1-2-4-14(13)29-16-11-15(19(21,22)23)25-17(26-16)27-8-5-18(6-9-27)12-24-7-10-28-18/h1-4,11,24H,5-10,12H2	FXQQYKFRGWXMDW-UHFFFAOYSA-N	375676	US9908897, Example 57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375676	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375676&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960544	404344704							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750246	FC(F)(F)c1cc(Oc2cccc(c2)C#N)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C20H20F3N5O2/c21-20(22,23)16-11-17(30-15-3-1-2-14(10-15)12-24)27-18(26-16)28-7-4-19(5-8-28)13-25-6-9-29-19/h1-3,10-11,25H,4-9,13H2	LVTITHFSOZBRMM-UHFFFAOYSA-N	375680	US9908897, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 100							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375680	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375680&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960506	404344708							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750256	Fc1cccc(Oc2cc(nc(n2)N2CCC3(CC2)CNCCO3)C#N)c1	InChI=1S/C19H20FN5O2/c20-14-2-1-3-16(10-14)27-17-11-15(12-21)23-18(24-17)25-7-4-19(5-8-25)13-22-6-9-26-19/h1-3,10-11,22H,4-9,13H2	FRYWDPTWXKMFIV-UHFFFAOYSA-N	375683	US9908897, Example 62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 316							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375683	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375683&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960388	404344711							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750266	Fc1cccc(Oc2cc(nc(n2)N2CCC3(CC2)CNCCO3)C2CC2)c1	InChI=1S/C21H25FN4O2/c22-16-2-1-3-17(12-16)28-19-13-18(15-4-5-15)24-20(25-19)26-9-6-21(7-10-26)14-23-8-11-27-21/h1-3,12-13,15,23H,4-11,14H2	CLTNRKNBPJLOCT-UHFFFAOYSA-N	375686	US9908897, Example 65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375686	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375686&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960385	404344714							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750270	COc1cc(Oc2cccc(F)c2)nc(n1)N1CCC2(CC1)CNCCO2	InChI=1S/C19H23FN4O3/c1-25-16-12-17(27-15-4-2-3-14(20)11-15)23-18(22-16)24-8-5-19(6-9-24)13-21-7-10-26-19/h2-4,11-12,21H,5-10,13H2,1H3	LCJBANUDMYBFLQ-UHFFFAOYSA-N	375687	US9908897, Example 66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375687	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375687&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960396	404344715							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750277	Fc1cccc(Oc2cc(nc(n2)N2CCC3(CC2)CNC(=O)CO3)C(F)(F)F)c1	InChI=1S/C19H18F4N4O3/c20-12-2-1-3-13(8-12)30-16-9-14(19(21,22)23)25-17(26-16)27-6-4-18(5-7-27)11-24-15(28)10-29-18/h1-3,8-9H,4-7,10-11H2,(H,24,28)	JZANIIBHVHLPQJ-UHFFFAOYSA-N	375689	US9908897, Example 68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375689	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375689&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960615	404344717							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750284	Fc1cccc(Oc2cc(nc(n2)N2CCC3(CC2)CNCC(F)(F)O3)C(F)(F)F)c1	InChI=1S/C19H18F6N4O2/c20-12-2-1-3-13(8-12)30-15-9-14(19(23,24)25)27-16(28-15)29-6-4-17(5-7-29)10-26-11-18(21,22)31-17/h1-3,8-9,26H,4-7,10-11H2	RYIWMFCNGOZYFZ-UHFFFAOYSA-N	375691	US9908897, Example 70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375691	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375691&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960547	404344719							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750288	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(CC2)CNCCS3(=O)=O)c1	InChI=1S/C20H21F3N2O3S/c21-14-2-1-3-15(10-14)28-19-12-17(23)16(22)11-18(19)25-7-4-20(5-8-25)13-24-6-9-29(20,26)27/h1-3,10-12,24H,4-9,13H2	UWTVKQZJBXVLFQ-UHFFFAOYSA-N	375692	US9908897, Example 71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7943							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375692	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375692&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960528	404344720							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750292	Fc1cccc(Oc2cc(nc(n2)N2CCC3(CC2)CNCCS3(=O)=O)C(F)(F)F)c1	InChI=1S/C19H20F4N4O3S/c20-13-2-1-3-14(10-13)30-16-11-15(19(21,22)23)25-17(26-16)27-7-4-18(5-8-27)12-24-6-9-31(18,28)29/h1-3,10-11,24H,4-9,12H2	IVASDCSVTRNREB-UHFFFAOYSA-N	375693	US9908897, Example 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3162							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375693	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375693&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960526	404344721							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750314	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(CCCNC3)CC2)c1	InChI=1S/C21H23F3N2O/c22-15-3-1-4-16(11-15)27-20-13-18(24)17(23)12-19(20)26-9-6-21(7-10-26)5-2-8-25-14-21/h1,3-4,11-13,25H,2,5-10,14H2	BRHOSLMTYNSPCU-UHFFFAOYSA-N	375701	US9908897, Example 79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 794							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375701	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375701&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960449	404344729							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750324	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(CCNCC3)CC2)c1	InChI=1S/C21H23F3N2O/c22-15-2-1-3-16(12-15)27-20-14-18(24)17(23)13-19(20)26-10-6-21(7-11-26)4-8-25-9-5-21/h1-3,12-14,25H,4-11H2	TVKDOMFQEAUPSL-UHFFFAOYSA-N	375704	US9908897, Example 82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375704	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375704&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960597	404344732							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750328	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(C2)CNCCO3)c1	InChI=1S/C19H19F3N2O2/c20-13-2-1-3-14(8-13)26-18-10-16(22)15(21)9-17(18)24-6-4-19(12-24)11-23-5-7-25-19/h1-3,8-10,23H,4-7,11-12H2	GRAFMJZTCPAZBX-UHFFFAOYSA-N	375705	US9908897, Example 83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 631							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375705	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375705&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960476	404344733							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750332	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(C2)CCCNC3)c1	InChI=1S/C20H21F3N2O/c21-14-3-1-4-15(9-14)26-19-11-17(23)16(22)10-18(19)25-8-6-20(13-25)5-2-7-24-12-20/h1,3-4,9-11,24H,2,5-8,12-13H2	UDALZSDRQUNHRU-UHFFFAOYSA-N	375706	US9908897, Example 84	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 251							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375706	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375706&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960569	404344734							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750342	Fc1cccc(Oc2cc(nc(n2)N2CCC3(C2)CNCCC32OCCO2)C(F)(F)F)c1	InChI=1S/C21H22F4N4O3/c22-14-2-1-3-15(10-14)32-17-11-16(21(23,24)25)27-18(28-17)29-7-5-19(13-29)12-26-6-4-20(19)30-8-9-31-20/h1-3,10-11,26H,4-9,12-13H2	WFLWDHGEOJNXCT-UHFFFAOYSA-N	375709	US9908897, Example 87	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375709	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375709&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			130398615	404344737							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750349	Fc1cccc(Oc2cc(nc(n2)N2CCC3(CNC(=O)O3)CC2)C(F)(F)F)c1	InChI=1S/C18H16F4N4O3/c19-11-2-1-3-12(8-11)28-14-9-13(18(20,21)22)24-15(25-14)26-6-4-17(5-7-26)10-23-16(27)29-17/h1-3,8-9H,4-7,10H2,(H,23,27)	MUMVFZQOXPRNRA-UHFFFAOYSA-N	375713	US9908897, Example 89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375713	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375713&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960425	404344741							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750353	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(C2)CCNCC3)c1	InChI=1S/C20H21F3N2O/c21-14-2-1-3-15(10-14)26-19-12-17(23)16(22)11-18(19)25-9-6-20(13-25)4-7-24-8-5-20/h1-3,10-12,24H,4-9,13H2	RVNWULIOIKDRNY-UHFFFAOYSA-N	375714	US9908897, Example 90	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 794							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375714	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375714&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960421	404344742							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750357	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(CCNC3)CC2)c1	InChI=1S/C20H21F3N2O/c21-14-2-1-3-15(10-14)26-19-12-17(23)16(22)11-18(19)25-8-5-20(6-9-25)4-7-24-13-20/h1-3,10-12,24H,4-9,13H2	XZGDMJHTSNODSG-UHFFFAOYSA-N	375715	US9908897, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1259							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375715	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375715&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960541	404344743							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750361	Fc1cccc(Oc2cc(F)cc(c2)N2CCC3(CCNC3)CC2)c1	InChI=1S/C20H22F2N2O/c21-15-2-1-3-18(11-15)25-19-12-16(22)10-17(13-19)24-8-5-20(6-9-24)4-7-23-14-20/h1-3,10-13,23H,4-9,14H2	MHZZVGCHJXSMAS-UHFFFAOYSA-N	375716	US9908897, Example 92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 631							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375716	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375716&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118960353	404344744							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750365	Fc1cccc(Oc2cc(F)c(F)cc2N2CCC3(C2)CCNCC32OCCO2)c1	InChI=1S/C22H23F3N2O3/c23-15-2-1-3-16(10-15)30-20-12-18(25)17(24)11-19(20)27-7-5-21(14-27)4-6-26-13-22(21)28-8-9-29-22/h1-3,10-12,26H,4-9,13-14H2	PQAOCWPDIGYQJX-UHFFFAOYSA-N	375717	US9908897, Example 93::US9908897, Example 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375717	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375717&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118974370	404344745							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
750372	Fc1cccc(Oc2cc(nc(n2)N2CCC3(C2)CCNCC32OCCO2)C(F)(F)F)c1	InChI=1S/C21H22F4N4O3/c22-14-2-1-3-15(10-14)32-17-11-16(21(23,24)25)27-18(28-17)29-7-5-19(13-29)4-6-26-12-20(19)30-8-9-31-20/h1-3,10-11,26H,4-9,12-13H2	YFYTXCHIKLXUIM-UHFFFAOYSA-N	375719	US9908897, Example 95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2512							US Patent		10.7270/Q2P55QTW		aid1798317	US9908897	Cremonesi, S; Luker, T; Semeraro, T; Micheli, F	3/6/2018	1/27/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=375719	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=375719&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118974663	404344746							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753435	CN(C)CC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C19H22F4N4O2/c1-26(2)12-18(28)6-8-27(9-7-18)17-24-15(19(21,22)23)11-16(25-17)29-14-5-3-4-13(20)10-14/h3-5,10-11,28H,6-9,12H2,1-2H3	CNNSTIWPQJEDBI-UHFFFAOYSA-N	376871	4-[(dimethylamino)methyl]-1-[4-(3-fluorophenoxy)-6(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol (E1)::US9920053, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 251							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376871	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958624	404345874							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753439	OC1(CN2CCCC2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C21H24F4N4O2/c22-15-4-3-5-16(12-15)31-18-13-17(21(23,24)25)26-19(27-18)29-10-6-20(30,7-11-29)14-28-8-1-2-9-28/h3-5,12-13,30H,1-2,6-11,14H2	GRYXYXQISNGOHR-UHFFFAOYSA-N	376872	1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-(pyrrolidin-1-ylmethyl)piperidin-4-ol (E2)::US9920053, Example 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 200							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376872&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958585	404345875							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753443	OC1(CNC2CC2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C20H22F4N4O2/c21-13-2-1-3-15(10-13)30-17-11-16(20(22,23)24)26-18(27-17)28-8-6-19(29,7-9-28)12-25-14-4-5-14/h1-3,10-11,14,25,29H,4-9,12H2	PSJGFAIPMGIRNZ-UHFFFAOYSA-N	376873	4-[(cyclopropylamino)methyl]-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol (E3)::US9920053, Example 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958528	404345876							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753447	CN(CC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F)C1CC1	InChI=1S/C21H24F4N4O2/c1-28(15-5-6-15)13-20(30)7-9-29(10-8-20)19-26-17(21(23,24)25)12-18(27-19)31-16-4-2-3-14(22)11-16/h2-4,11-12,15,30H,5-10,13H2,1H3	LUNVJLGVMLVBOP-UHFFFAOYSA-N	376874	4-{[cyclopropyl(methyl)amino]methyl}-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol (E4)::US9920053, Example 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 794							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376874&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958715	404345877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753451	CNCC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C18H20F4N4O2/c1-23-11-17(27)5-7-26(8-6-17)16-24-14(18(20,21)22)10-15(25-16)28-13-4-2-3-12(19)9-13/h2-4,9-10,23,27H,5-8,11H2,1H3	ZLISGDJBRPIOSW-UHFFFAOYSA-N	376875	1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-[(methylamino)methyl]piperidin-4-ol (E5)::US9920053, Example 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376875&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958439	404345878							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753455	OC1(CN2CCC(F)(F)C2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C21H22F6N4O2/c22-14-2-1-3-15(10-14)33-17-11-16(21(25,26)27)28-18(29-17)31-8-4-19(32,5-9-31)12-30-7-6-20(23,24)13-30/h1-3,10-11,32H,4-9,12-13H2	LQDWXHHCAMQVNK-UHFFFAOYSA-N	376876	4-[(3,3-difluoropyrrolidin-1-yl)methyl]-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol (E6)::US9920053, Example 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10000							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958743	404345879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753459	OC1(CN2CCCNCC2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C22H27F4N5O2/c23-16-3-1-4-17(13-16)33-19-14-18(22(24,25)26)28-20(29-19)31-10-5-21(32,6-11-31)15-30-9-2-7-27-8-12-30/h1,3-4,13-14,27,32H,2,5-12,15H2	MYMJLIYEKOEEJB-UHFFFAOYSA-N	376877	4-(1,4-diazepan-1-ylmethyl)-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol hydrochloride (E7)::US9920053, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1585							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376877&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958406	404345880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753463	CC1CCC(C)N1CC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C23H28F4N4O2/c1-15-6-7-16(2)31(15)14-22(32)8-10-30(11-9-22)21-28-19(23(25,26)27)13-20(29-21)33-18-5-3-4-17(24)12-18/h3-5,12-13,15-16,32H,6-11,14H2,1-2H3	YUGLAKINIYKKIY-UHFFFAOYSA-N	376878	4-[(2,5-dimethylpyrrolidin-1-yl)methyl]-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol (E8)::US9920053, Example 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 158							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376878&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958698	404345881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753473	NCC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C17H18F4N4O2/c18-11-2-1-3-12(8-11)27-14-9-13(17(19,20)21)23-15(24-14)25-6-4-16(26,10-22)5-7-25/h1-3,8-9,26H,4-7,10,22H2	HYEMQFSXSZXWCD-UHFFFAOYSA-N	376881	4-(aminomethyl)-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol (E11)::US9920053, Example 12::US9920053, Example 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1585							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376881	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376881&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958207	404345884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753480	NCC1(F)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C17H17F5N4O/c18-11-2-1-3-12(8-11)27-14-9-13(17(20,21)22)24-15(25-14)26-6-4-16(19,10-23)5-7-26/h1-3,8-9H,4-7,10,23H2	IVAWEHPZJGWCPZ-UHFFFAOYSA-N	376883	{4-fluoro-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl}methanamine (E13)::US9920053, Example 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3981							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376883	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376883&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958612	404345885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753496	NCC1(O)CCN(CC1)c1cc(Oc2cccc(F)c2)cc(F)c1F	InChI=1S/C18H19F3N2O2/c19-12-2-1-3-13(8-12)25-14-9-15(20)17(21)16(10-14)23-6-4-18(24,11-22)5-7-23/h1-3,8-10,24H,4-7,11,22H2	XFWSYJVLQVKQDN-UHFFFAOYSA-N	376888	4-(aminomethyl)-1-[2,3-difluoro-5-(3-fluorophenoxy)phenyl]piperidin-4-ol (E18)::US9920053, Example 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376888	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376888&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958158	404345890							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753500	NCC1(O)CCN(CC1)c1cc(F)c(F)c(Oc2cccc(F)c2)c1	InChI=1S/C18H19F3N2O2/c19-12-2-1-3-14(8-12)25-16-10-13(9-15(20)17(16)21)23-6-4-18(24,11-22)5-7-23/h1-3,8-10,24H,4-7,11,22H2	RZKJUZNVAKAQIB-UHFFFAOYSA-N	376889	4-(aminomethyl)-1-[3,4-difluoro-5-(3-fluorophenoxy)phenyl]piperidin-4-ol (E19)::US9920053, Example 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 794							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376889&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958617	404345891							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753507	CC(C)C(=O)NCC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C21H24F4N4O3/c1-13(2)18(30)26-12-20(31)6-8-29(9-7-20)19-27-16(21(23,24)25)11-17(28-19)32-15-5-3-4-14(22)10-15/h3-5,10-11,13,31H,6-9,12H2,1-2H3,(H,26,30)	GPJXMLFNJCHMAK-UHFFFAOYSA-N	376891	N-({1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-hydroxypiperidin-4-yl}methyl)-2-methylpropanamide (E21)::US9920053, Example 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10000							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376891	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376891&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958555	404345893							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753520	OC1(CNC(=O)C2CNC2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C21H23F4N5O3/c22-14-2-1-3-15(8-14)33-17-9-16(21(23,24)25)28-19(29-17)30-6-4-20(32,5-7-30)12-27-18(31)13-10-26-11-13/h1-3,8-9,13,26,32H,4-7,10-12H2,(H,27,31)	BDYJSRVPCMSGOT-UHFFFAOYSA-N	376895	N-({1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-hydroxypiperidin-4-yl}methyl)azetidine-3-carboxamide (E25)::US9920053, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<10000							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376895	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376895&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958694	404345897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753524	OC1(CNC(=O)c2ccccc2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C24H22F4N4O3/c25-17-7-4-8-18(13-17)35-20-14-19(24(26,27)28)30-22(31-20)32-11-9-23(34,10-12-32)15-29-21(33)16-5-2-1-3-6-16/h1-8,13-14,34H,9-12,15H2,(H,29,33)	KNENTTYNZCIRQS-UHFFFAOYSA-N	376896	N-({1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-hydroxypiperidin-4-yl}methyl)benzamide (E26)::US9920053, Example 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3162							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376896	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376896&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958611	404345898							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753528	OC1(CNC(=O)c2cn[nH]c2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C21H20F4N6O3/c22-14-2-1-3-15(8-14)34-17-9-16(21(23,24)25)29-19(30-17)31-6-4-20(33,5-7-31)12-26-18(32)13-10-27-28-11-13/h1-3,8-11,33H,4-7,12H2,(H,26,32)(H,27,28)	AUYRMMWRSKKNRI-UHFFFAOYSA-N	376897	N-({1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-hydroxypiperidin-4-yl}methyl)-1H-pyrazole-4-carboxamide (E27)::US9920053, Example 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5012							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376897	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376897&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958737	404345899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753532	OC1(CNC(=O)c2cnccn2)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C22H20F4N6O3/c23-14-2-1-3-15(10-14)35-18-11-17(22(24,25)26)30-20(31-18)32-8-4-21(34,5-9-32)13-29-19(33)16-12-27-6-7-28-16/h1-3,6-7,10-12,34H,4-5,8-9,13H2,(H,29,33)	GECVFCYHTYLHEA-UHFFFAOYSA-N	376898	N-({1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-hydroxypiperidin-4-yl}methyl)pyrazine-2-carboxamide (E28)::US9920053, Example 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3162							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376898&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958446	404345900							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753536	NCC(=O)NCC1(O)CCN(CC1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C19H21F4N5O3/c20-12-2-1-3-13(8-12)31-16-9-14(19(21,22)23)26-17(27-16)28-6-4-18(30,5-7-28)11-25-15(29)10-24/h1-3,8-9,30H,4-7,10-11,24H2,(H,25,29)	ZOFRLWVABVATNM-UHFFFAOYSA-N	376899	2-amino-N-({1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-4-hydroxypiperidin-4-yl}methyl)acetamide (E29)::US9920053, Example 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3981							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376899&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958475	404345901							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753543	O[C@]1(CNC2CC2)CCN(C1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F |r|	InChI=1S/C19H20F4N4O2/c20-12-2-1-3-14(8-12)29-16-9-15(19(21,22)23)25-17(26-16)27-7-6-18(28,11-27)10-24-13-4-5-13/h1-3,8-9,13,24,28H,4-7,10-11H2	PBLWXFOIRNATKO-UHFFFAOYSA-N	376901	(3S or 3R)-3-[(cyclopropylamino)methyl]-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]pyrrolidin-3-ol (E31) and (3R or 3S)-3-[(cyclopropylamino)methyl]-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]pyrrolidin-3-ol (E32)::US9920053, Example 31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1995							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376901&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118974256	404345903							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753547	NCC1(O)CCN(C1)c1nc(Oc2cccc(F)c2)cc(n1)C(F)(F)F	InChI=1S/C16H16F4N4O2/c17-10-2-1-3-11(6-10)26-13-7-12(16(18,19)20)22-14(23-13)24-5-4-15(25,8-21)9-24/h1-3,6-7,25H,4-5,8-9,21H2	WYASFUKPHAHHLE-UHFFFAOYSA-N	376902	3-(aminomethyl)-1-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]pyrrolidin-3-ol (E33)::US9920053, Example 33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1585							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376902&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958401	404345904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753557	Fc1cccc(Oc2cc(nc(n2)N2CCc3nc[nH]c3C2)C(F)(F)F)c1	InChI=1S/C17H13F4N5O/c18-10-2-1-3-11(6-10)27-15-7-14(17(19,20)21)24-16(25-15)26-5-4-12-13(8-26)23-9-22-12/h1-3,6-7,9H,4-5,8H2,(H,22,23)	YRSBMPKJFDYYFO-UHFFFAOYSA-N	376905	4-(3-fluorophenoxy)-2-{3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-6-(trifluoromethyl)pyrimidine (E36)::US9920053, Example 36	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2512							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376905	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376905&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958546	404345907							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
753561	Fc1cccc(Oc2cc(nc(n2)N2CCC3NCCCC3C2)C(F)(F)F)c1	InChI=1S/C19H20F4N4O/c20-13-4-1-5-14(9-13)28-17-10-16(19(21,22)23)25-18(26-17)27-8-6-15-12(11-27)3-2-7-24-15/h1,4-5,9-10,12,15,24H,2-3,6-8,11H2	SKEFXGBGLIGVDP-UHFFFAOYSA-N	376906	6-[4-(3-fluorophenoxy)-6-(trifluoromethyl)pyrimidin-2-yl]-decahydro-1,6-naphthyridine hydrochloride (E39)::US9920053, Example 39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 631							US Patent		10.7270/Q2M90C0V		aid1798356	US9920053	Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L; Luker, T; Leslie, C	3/20/2018	2/4/2020	Chronos Therapeutics	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=376906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=376906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118958421	404345908							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
775502	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US9968610, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2ZW1P6M		aid1798745	US10294230	Shapiro, G	5/21/2019	3/10/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
775504	Cc1ccc(COC(=O)N2CC[C@H](CNc3nccn4cnnc34)C(F)(F)C2)cc1 |r|	InChI=1S/C20H22F2N6O2/c1-14-2-4-15(5-3-14)11-30-19(29)27-8-6-16(20(21,22)12-27)10-24-17-18-26-25-13-28(18)9-7-23-17/h2-5,7,9,13,16H,6,8,10-12H2,1H3,(H,23,24)	VUFCSTHNGFATSK-UHFFFAOYSA-N	388294	US10294230, Compound E1-1.2::US10584127, Compound E1-1.2::US11136328, Compound E1-1.2::US11752155, Compound E1-1.2B'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 40000							US Patent		10.7270/Q2ZW1P6M		aid1798745	US10294230	Shapiro, G	5/21/2019	3/10/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388294&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			124107498	404857356							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
775509	Cc1ccc(COC(=O)N2CC[C@@H](CNc3ncc4cn[nH]c4n3)C(F)(F)C2)cc1 |r|	InChI=1S/C20H22F2N6O2/c1-13-2-4-14(5-3-13)11-30-19(29)28-7-6-16(20(21,22)12-28)10-24-18-23-8-15-9-25-27-17(15)26-18/h2-5,8-9,16H,6-7,10-12H2,1H3,(H2,23,24,25,26,27)	YCJDFVJNRWEUDF-UHFFFAOYSA-N	388298	US10294230, Compound E1-8.2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6800							US Patent		10.7270/Q2ZW1P6M		aid1798745	US10294230	Shapiro, G	5/21/2019	3/10/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388298	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388298&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			145996474	404857360							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
775513	Cc1ccc(COC(=O)N2CC[C@H](CNc3ncccn3)C(F)(F)C2)cc1 |r|	InChI=1S/C19H22F2N4O2/c1-14-3-5-15(6-4-14)12-27-18(26)25-10-7-16(19(20,21)13-25)11-24-17-22-8-2-9-23-17/h2-6,8-9,16H,7,10-13H2,1H3,(H,22,23,24)	DTERKQCKRBDMMH-UHFFFAOYSA-N	388301	US10294230, Compound E1-22.2::US10584127, Compound E1-22.2::US11136328, Compound E1-22.2::US11752155, Compound E1-22.2B'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2ZW1P6M		aid1798745	US10294230	Shapiro, G	5/21/2019	3/10/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388301	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388301&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			124107516	404857363							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
775996	CNC[C@@H]([C@H](OCC(=O)NC)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C23H26N2O2/c1-24-15-21(20-13-12-17-8-6-7-11-19(17)14-20)23(27-16-22(26)25-2)18-9-4-3-5-10-18/h3-14,21,23-24H,15-16H2,1-2H3,(H,25,26)	UCAUHLPHMUPKJI-UHFFFAOYSA-N	388467	US9944618, Compound ID No. 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388467	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388467&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675454	404957113							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776001	CNCC(Cc1ccccc1CO)c1ccc2ccccc2c1	InChI=1S/C21H23NO/c1-22-14-21(13-18-8-4-5-9-20(18)15-23)19-11-10-16-6-2-3-7-17(16)12-19/h2-12,21-23H,13-15H2,1H3	BUZAYDYQPINNKR-UHFFFAOYSA-N	388468	US9944618, Compound ID No. 90::US9944618, Compound ID No. 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388468&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288291	404957114							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776006	CNC[C@@H]([C@H](OCC(N)=O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C22H24N2O2/c1-24-14-20(19-12-11-16-7-5-6-10-18(16)13-19)22(26-15-21(23)25)17-8-3-2-4-9-17/h2-13,20,22,24H,14-15H2,1H3,(H2,23,25)	WLEFUQDCECJVNK-UHFFFAOYSA-N	388469	US9944618, Compound ID No. 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388469&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			81689699	404957115							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776012	CN1CO[C@@H]([C@H](C1)c1ccc2ccccc2c1)c1ccccc1 |r|	InChI=1S/C21H21NO/c1-22-14-20(21(23-15-22)17-8-3-2-4-9-17)19-12-11-16-7-5-6-10-18(16)13-19/h2-13,20-21H,14-15H2,1H3	JQCWMOSUIVYTTK-UHFFFAOYSA-N	388470	US9944618, Compound ID No. 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388470	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388470&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44156242	404957116							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776018	CNC[C@@H](Cc1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H21N/c1-21-15-20(13-16-7-3-2-4-8-16)19-12-11-17-9-5-6-10-18(17)14-19/h2-12,14,20-21H,13,15H2,1H3	OXFLDCMTABTCAE-UHFFFAOYSA-N	388471	US9944618, Compound ID No. 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6500							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388471	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388471&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			68735781	404957117							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776024	CCNC(=O)CO[C@@H]([C@H](CNC)c1ccc2ccccc2c1)c1ccccc1 |r|	InChI=1S/C24H28N2O2/c1-3-26-23(27)17-28-24(19-10-5-4-6-11-19)22(16-25-2)21-14-13-18-9-7-8-12-20(18)15-21/h4-15,22,24-25H,3,16-17H2,1-2H3,(H,26,27)	XOZXKGSJBABZIV-UHFFFAOYSA-N	388472	US9944618, Compound ID No. 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388472	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388472&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288292	404957118							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776029	CNC[C@@H]([C@@H](O)c1ccncc1Cl)c1ccc2ccccc2c1 |r|	InChI=1S/C19H19ClN2O/c1-21-11-17(19(23)16-8-9-22-12-18(16)20)15-7-6-13-4-2-3-5-14(13)10-15/h2-10,12,17,19,21,23H,11H2,1H3	SFVRYZSALZWGIG-UHFFFAOYSA-N	388473	US9944618, Compound ID No. 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388473	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388473&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288293	404957119							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776038	CNC[C@@H]([C@H](F)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20FN/c1-22-14-19(20(21)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-20,22H,14H2,1H3	MUJUHKBLFFBHAD-UHFFFAOYSA-N	388475	US9944618, Compound ID No. 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9500							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388475	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388475&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44156360	404957121							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776044	CNC[C@@H]([C@H](O)c1ccccc1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H17Cl2NO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	RAPMQRUFYZBKQI-UHFFFAOYSA-N	388476	US9944618, Compound ID No. 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388476	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388476&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288294	404957122							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776050	CNC[C@@H]([C@@H](F)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20FN/c1-22-14-19(20(21)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-20,22H,14H2,1H3	MUJUHKBLFFBHAD-UHFFFAOYSA-N	388477	US9944618, Compound ID No. 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388477	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388477&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44137267	404957123							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776056	CNC[C@@H]([C@H](O)c1ccncc1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H20N2O/c1-20-13-18(19(22)15-8-10-21-11-9-15)17-7-6-14-4-2-3-5-16(14)12-17/h2-12,18-20,22H,13H2,1H3	ZCQPZBAAOWWMGM-UHFFFAOYSA-N	388478	US9944618, Compound ID No. 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8400							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388478	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388478&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288295	404957124							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776062	CNC[C@@H]([C@H](OCC(=O)NC1CC1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C25H28N2O2/c1-26-16-23(21-12-11-18-7-5-6-10-20(18)15-21)25(19-8-3-2-4-9-19)29-17-24(28)27-22-13-14-22/h2-12,15,22-23,25-26H,13-14,16-17H2,1H3,(H,27,28)	UXMMZUYNKQSOKI-UHFFFAOYSA-N	388479	US9944618, Compound ID No. 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 19000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388479	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388479&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675468	404957125							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776068	CNC[C@@H]([C@H](OCC(=O)NCCO)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C24H28N2O3/c1-25-16-22(21-12-11-18-7-5-6-10-20(18)15-21)24(19-8-3-2-4-9-19)29-17-23(28)26-13-14-27/h2-12,15,22,24-25,27H,13-14,16-17H2,1H3,(H,26,28)	CZSNCUMOYBWBAT-UHFFFAOYSA-N	388480	US9944618, Compound ID No. 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388480	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388480&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288362	404957126					C04080		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776074	CNC[C@@H]([C@H](O)c1ccccc1F)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20FNO/c1-22-13-18(20(23)17-8-4-5-9-19(17)21)16-11-10-14-6-2-3-7-15(14)12-16/h2-12,18,20,22-23H,13H2,1H3	SIHJLDGXFAZQND-UHFFFAOYSA-N	388481	US9944618, Compound ID No. 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388481	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388481&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288363	404957127							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776080	CNCC([C@H](O)c1ccccc1)c1ccc(Br)c(Cl)c1 |r|	InChI=1S/C16H17BrClNO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	YYXLUZNBTYTCJI-UHFFFAOYSA-N	388482	US9944618, Compound ID No. 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388482	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388482&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134420021	404957128							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776086	CNCC(Cc1ccccc1F)c1ccc2ccccc2c1	InChI=1S/C20H20FN/c1-22-14-19(13-18-8-4-5-9-20(18)21)17-11-10-15-6-2-3-7-16(15)12-17/h2-12,19,22H,13-14H2,1H3	DZNPDBNQTFEIMC-UHFFFAOYSA-N	388483	US9944618, Compound ID No. 36::US9944618, Compound ID No. 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7900							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388483&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288522	404957129							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776092	CNC[C@@H]([C@H](OCc1cc(C)on1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C25H26N2O2/c1-18-14-23(27-29-18)17-28-25(20-9-4-3-5-10-20)24(16-26-2)22-13-12-19-8-6-7-11-21(19)15-22/h3-15,24-26H,16-17H2,1-2H3	BIAPMBIBJRGUDT-UHFFFAOYSA-N	388484	US9944618, Compound ID No. 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4600							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388484	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388484&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288364	404957130							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776097	CNC[C@@H]([C@H](OCC(=O)N1CC[C@H](O)C1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C26H30N2O3/c1-27-16-24(22-12-11-19-7-5-6-10-21(19)15-22)26(20-8-3-2-4-9-20)31-18-25(30)28-14-13-23(29)17-28/h2-12,15,23-24,26-27,29H,13-14,16-18H2,1H3	SDXIHKSUCKYXFP-UHFFFAOYSA-N	388485	US9944618, Compound ID No. 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388485	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388485&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288365	404957131							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776103	CNC[C@@H]([C@H](OCc1cc(C)no1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C25H26N2O2/c1-18-14-23(29-27-18)17-28-25(20-9-4-3-5-10-20)24(16-26-2)22-13-12-19-8-6-7-11-21(19)15-22/h3-15,24-26H,16-17H2,1-2H3	CEMMWBPYOOIVQO-UHFFFAOYSA-N	388486	US9944618, Compound ID No. 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4700							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388486	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388486&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288366	404957132							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776107	CNC[C@@H]([C@@H](O)c1ccccc1)c1ccc(Br)c(Cl)c1 |r|	InChI=1S/C16H17BrClNO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	YYXLUZNBTYTCJI-UHFFFAOYSA-N	388487	US9944618, Compound ID No. 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388487	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388487&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288367	404957133							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776113	CNC[C@@H]([C@H](OCc1noc(C)n1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C24H25N3O2/c1-17-26-23(27-29-17)16-28-24(19-9-4-3-5-10-19)22(15-25-2)21-13-12-18-8-6-7-11-20(18)14-21/h3-14,22,24-25H,15-16H2,1-2H3	TZAVKSRQDZRHCW-UHFFFAOYSA-N	388488	US9944618, Compound ID No. 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388488	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388488&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288368	404957134							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776119	CNC[C@@H]([C@H](OCC(=O)N1CCOCC1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C26H30N2O3/c1-27-18-24(23-12-11-20-7-5-6-10-22(20)17-23)26(21-8-3-2-4-9-21)31-19-25(29)28-13-15-30-16-14-28/h2-12,17,24,26-27H,13-16,18-19H2,1H3	RLWDFQXBVPUYFD-UHFFFAOYSA-N	388489	US9944618, Compound ID No. 23	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388489	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388489&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288440	404957135							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776125	CNC[C@@H]([C@H](O)c1cccc(N)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H18Cl2N2O/c1-20-9-13(10-5-6-14(17)15(18)8-10)16(21)11-3-2-4-12(19)7-11/h2-8,13,16,20-21H,9,19H2,1H3	BQCHSJJIVZNPPW-UHFFFAOYSA-N	388490	US9944618, Compound ID No. 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388490	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388490&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675525	404957136							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776131	CNCC([C@H](CO)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-22-14-20(21(15-23)17-8-3-2-4-9-17)19-12-11-16-7-5-6-10-18(16)13-19/h2-13,20-23H,14-15H2,1H3	CUSKZMGSNSWKJU-UHFFFAOYSA-N	388491	US9944618, Compound ID No. 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388491	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388491&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288442	404957137							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776136	CNC[C@@H]([C@H](O)c1ccc(Cl)nc1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H19ClN2O/c1-21-12-17(19(23)16-8-9-18(20)22-11-16)15-7-6-13-4-2-3-5-14(13)10-15/h2-11,17,19,21,23H,12H2,1H3	XTWPREAANUBKMC-UHFFFAOYSA-N	388492	US9944618, Compound ID No. 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7500							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388492	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388492&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675699	404957138							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776145	CNC[C@@H]([C@H](O)c1ccccc1C)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-15-7-3-6-10-19(15)21(23)20(14-22-2)18-12-11-16-8-4-5-9-17(16)13-18/h3-13,20-23H,14H2,1-2H3	BWFVXYOMRCPBMK-UHFFFAOYSA-N	388494	US9944618, Compound ID No. 56::US9944618, Compound ID No. 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388494&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288443	404957140							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776151	CCCNC(=O)CO[C@@H]([C@H](CNC)c1ccc2ccccc2c1)c1ccccc1 |r|	InChI=1S/C25H30N2O2/c1-3-15-27-24(28)18-29-25(20-10-5-4-6-11-20)23(17-26-2)22-14-13-19-9-7-8-12-21(19)16-22/h4-14,16,23,25-26H,3,15,17-18H2,1-2H3,(H,27,28)	IIMALBJVIZZYSR-UHFFFAOYSA-N	388495	US9944618, Compound ID No. 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388495	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388495&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288444	404957141							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776156	CNC[C@@H]([C@H](OCC(=O)N1CCC1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C25H28N2O2/c1-26-17-23(22-13-12-19-8-5-6-11-21(19)16-22)25(20-9-3-2-4-10-20)29-18-24(28)27-14-7-15-27/h2-6,8-13,16,23,25-26H,7,14-15,17-18H2,1H3	JIZLZTXHTCSSNE-UHFFFAOYSA-N	388496	US9944618, Compound ID No. 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 29000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388496	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388496&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288445	404957142							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776163	CNC[C@@H]([C@H](OCCO)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C22H25NO2/c1-23-16-21(20-12-11-17-7-5-6-10-19(17)15-20)22(25-14-13-24)18-8-3-2-4-9-18/h2-12,15,21-24H,13-14,16H2,1H3	BYONOHOEJBSVPL-UHFFFAOYSA-N	388498	US9944618, Compound ID No. 32	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 22000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388498&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288519	404957144							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776169	CNC[C@@H]([C@H](OCC(=O)N(C)C)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C24H28N2O2/c1-25-16-22(21-14-13-18-9-7-8-12-20(18)15-21)24(19-10-5-4-6-11-19)28-17-23(27)26(2)3/h4-15,22,24-25H,16-17H2,1-3H3	HJIWZBXNUUWREM-UHFFFAOYSA-N	388499	US9944618, Compound ID No. 33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388499	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388499&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288520	404957145							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776174	CNC[C@@H]([C@H](OCC(=O)N1CC[C@@H](O)C1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C26H30N2O3/c1-27-16-24(22-12-11-19-7-5-6-10-21(19)15-22)26(20-8-3-2-4-9-20)31-18-25(30)28-14-13-23(29)17-28/h2-12,15,23-24,26-27,29H,13-14,16-18H2,1H3	SDXIHKSUCKYXFP-UHFFFAOYSA-N	388500	US9944618, Compound ID No. 34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388500	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388500&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675596	404957146							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776180	CCOC(=O)CO[C@@H]([C@H](CNC)c1ccc2ccccc2c1)c1ccccc1 |r|	InChI=1S/C24H27NO3/c1-3-27-23(26)17-28-24(19-10-5-4-6-11-19)22(16-25-2)21-14-13-18-9-7-8-12-20(18)15-21/h4-15,22,24-25H,3,16-17H2,1-2H3	MZOKOQXAFVJKHQ-UHFFFAOYSA-N	388501	US9944618, Compound ID No. 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388501	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388501&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288521	404957147							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776185	CNCC(Cc1ccccc1F)c1ccc2ccccc2c1	InChI=1S/C20H20FN/c1-22-14-19(13-18-8-4-5-9-20(18)21)17-11-10-15-6-2-3-7-16(15)12-17/h2-12,19,22H,13-14H2,1H3	DZNPDBNQTFEIMC-UHFFFAOYSA-N	388483	US9944618, Compound ID No. 36::US9944618, Compound ID No. 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6200							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388483	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388483&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288522	404957129							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776194	CNCC(C(OC)c1ccccc1)c1ccc2ccccc2c1	InChI=1S/C21H23NO/c1-22-15-20(21(23-2)17-9-4-3-5-10-17)19-13-12-16-8-6-7-11-18(16)14-19/h3-14,20-22H,15H2,1-2H3	NEWPRFWUSPHJOT-UHFFFAOYSA-N	388504	US9944618, Compound ID No. 38	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388504	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388504&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44156113	404957149							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776200	CNCC(Cc1ccccc1C)c1ccc2ccccc2c1	InChI=1S/C21H23N/c1-16-7-3-4-9-18(16)13-21(15-22-2)20-12-11-17-8-5-6-10-19(17)14-20/h3-12,14,21-22H,13,15H2,1-2H3	GIXNEGGWWYHJGX-UHFFFAOYSA-N	388505	US9944618, Compound ID No. 134::US9944618, Compound ID No. 39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8200							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388505&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675480	404957150							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776206	CNCC(Cc1cccs1)c1ccc2ccccc2c1	InChI=1S/C18H19NS/c1-19-13-17(12-18-7-4-10-20-18)16-9-8-14-5-2-3-6-15(14)11-16/h2-11,17,19H,12-13H2,1H3	APFLBUWSTCFNIE-UHFFFAOYSA-N	388506	US9944618, Compound ID No. 40	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388506	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388506&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288525	404957151							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776217	C[C@](CN)(Cc1cccnc1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H20N2/c1-19(14-20,12-15-5-4-10-21-13-15)18-9-8-16-6-2-3-7-17(16)11-18/h2-11,13H,12,14,20H2,1H3	ZZLLQFDJKBAKCE-UHFFFAOYSA-N	388508	US9944618, Compound ID No. 42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 27000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388508	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388508&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675585	404957152							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776223	CNC[C@@H]([C@H](O)c1ccccc1)c1ccc(Br)c(Cl)c1 |r|	InChI=1S/C16H17BrClNO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	YYXLUZNBTYTCJI-UHFFFAOYSA-N	388509	US9944618, Compound ID No. 43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388509	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388509&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288600	404957153							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776229	CNC[C@@H](Cc1ccc(C)s1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H21NS/c1-14-7-10-19(21-14)12-18(13-20-2)17-9-8-15-5-3-4-6-16(15)11-17/h3-11,18,20H,12-13H2,1-2H3	ZTPBYUKSIHXSEW-UHFFFAOYSA-N	388510	US9944618, Compound ID No. 44	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3300							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388510	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388510&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288601	404957154							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776238	CNC[C@@H]([C@H](OC)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-22-15-20(21(23-2)17-9-4-3-5-10-17)19-13-12-16-8-6-7-11-18(16)14-19/h3-14,20-22H,15H2,1-2H3	NEWPRFWUSPHJOT-UHFFFAOYSA-N	388512	US9944618, Compound ID No. 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388512	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388512&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			68769963	404957156							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776244	CNC[C@@H]([C@H](O)c1cccs1)c1ccc2ccccc2c1 |r|	InChI=1S/C18H19NOS/c1-19-12-16(18(20)17-7-4-10-21-17)15-9-8-13-5-2-3-6-14(13)11-15/h2-11,16,18-20H,12H2,1H3	PKZICZJQJAOMKU-UHFFFAOYSA-N	388513	US9944618, Compound ID No. 47	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388513	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388513&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288599	404957157							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776250	CNCC(Cc1cccnc1)c1ccc2ccccc2c1	InChI=1S/C19H20N2/c1-20-14-19(11-15-5-4-10-21-13-15)18-9-8-16-6-2-3-7-17(16)12-18/h2-10,12-13,19-20H,11,14H2,1H3	ZBKRQGWGLHOYPX-UHFFFAOYSA-N	388514	US9944618, Compound ID No. 74::US9944618, Compound ID No. 48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388514&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288755	404957158							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776256	CNC[C@H]([C@@H](O)c1cccnc1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H20N2O/c1-20-13-18(19(22)17-7-4-10-21-12-17)16-9-8-14-5-2-3-6-15(14)11-16/h2-12,18-20,22H,13H2,1H3	QPWOFDKUJWRZFQ-UHFFFAOYSA-N	388515	US9944618, Compound ID No. 103::US9944618, Compound ID No. 49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388515	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388515&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287813	404957159							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776262	CNC[C@@H]([C@H](OCC(=O)N1CCCC1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C26H30N2O2/c1-27-18-24(23-14-13-20-9-5-6-12-22(20)17-23)26(21-10-3-2-4-11-21)30-19-25(29)28-15-7-8-16-28/h2-6,9-14,17,24,26-27H,7-8,15-16,18-19H2,1H3	SJBYDAUUDYGQIX-UHFFFAOYSA-N	388516	US9944618, Compound ID No. 50	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388516	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388516&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288602	404957160							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776270	CNCC(Cc1ccccc1O)c1ccc2ccccc2c1	InChI=1S/C20H21NO/c1-21-14-19(13-18-8-4-5-9-20(18)22)17-11-10-15-6-2-3-7-16(15)12-17/h2-12,19,21-22H,13-14H2,1H3	UUDREXTXTFFTKD-UHFFFAOYSA-N	388518	US9944618, Compound ID No. 69::US9944618, Compound ID No. 52	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388518&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288681	404957162							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776276	CNCC([C@H](O)c1ccccc1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H17Cl2NO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	RAPMQRUFYZBKQI-UHFFFAOYSA-N	388519	US9944618, Compound ID No. 53	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388519	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388519&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134420018	404957163							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776290	CNC[C@@H]([C@H](O)c1ccccc1C)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-15-7-3-6-10-19(15)21(23)20(14-22-2)18-12-11-16-8-4-5-9-17(16)13-18/h3-13,20-23H,14H2,1-2H3	BWFVXYOMRCPBMK-UHFFFAOYSA-N	388494	US9944618, Compound ID No. 56::US9944618, Compound ID No. 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 22000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388494	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388494&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288443	404957140							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776296	CNCC(Cc1ccccc1OC)c1ccc2ccccc2c1	InChI=1S/C21H23NO/c1-22-15-20(14-19-9-5-6-10-21(19)23-2)18-12-11-16-7-3-4-8-17(16)13-18/h3-13,20,22H,14-15H2,1-2H3	MRAZBVXMLFFLEZ-UHFFFAOYSA-N	388523	US9944618, Compound ID No. 132::US9944618, Compound ID No. 57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4700							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388523&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117604895	404957166							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776302	CNC[C@@H]([C@H](O)c1ccc(Cl)s1)c1ccc2ccccc2c1 |r|	InChI=1S/C18H18ClNOS/c1-20-11-15(18(21)16-8-9-17(19)22-16)14-7-6-12-4-2-3-5-13(12)10-14/h2-10,15,18,20-21H,11H2,1H3	MRMFTZLAVBPMMZ-UHFFFAOYSA-N	388524	US9944618, Compound ID No. 58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388524	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388524&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134419957	404957167							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776308	CNC[C@@H](Cc1cccnc1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C15H16Cl2N2/c1-18-10-13(7-11-3-2-6-19-9-11)12-4-5-14(16)15(17)8-12/h2-6,8-9,13,18H,7,10H2,1H3	OOCQXYIWPXQLSE-UHFFFAOYSA-N	388525	US9944618, Compound ID No. 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388525	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388525&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288605	404957168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776314	CNC[C@@H]([C@@H](O)c1ccccc1F)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20FNO/c1-22-13-18(20(23)17-8-4-5-9-19(17)21)16-11-10-14-6-2-3-7-15(14)12-16/h2-12,18,20,22-23H,13H2,1H3	SIHJLDGXFAZQND-UHFFFAOYSA-N	388526	US9944618, Compound ID No. 60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 28000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388526	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388526&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288606	404957169							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776320	CNC[C@@H]([C@@H](Cl)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20ClN/c1-22-14-19(20(21)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-20,22H,14H2,1H3	LZILTVHXOJJKON-UHFFFAOYSA-N	388527	US9944618, Compound ID No. 61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388527	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388527&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44156484	404957170							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776326	CNC[C@@H]([C@H](O)c1cccnc1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H20N2O/c1-20-13-18(19(22)17-7-4-10-21-12-17)16-9-8-14-5-2-3-6-15(14)11-16/h2-12,18-20,22H,13H2,1H3	QPWOFDKUJWRZFQ-UHFFFAOYSA-N	388528	US9944618, Compound ID No. 62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388528	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388528&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288675	404957171							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776332	CNC[C@@H]([C@@H](O)c1cccc(N)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H18Cl2N2O/c1-20-9-13(10-5-6-14(17)15(18)8-10)16(21)11-3-2-4-12(19)7-11/h2-8,13,16,20-21H,9,19H2,1H3	BQCHSJJIVZNPPW-UHFFFAOYSA-N	388529	US9944618, Compound ID No. 63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388529	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388529&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288676	404957172							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776338	C1CO[C@H]([C@@H](CN1)c1ccc2ccccc2c1)c1ccccc1 |r|	InChI=1S/C21H21NO/c1-2-7-17(8-3-1)21-20(15-22-12-13-23-21)19-11-10-16-6-4-5-9-18(16)14-19/h1-11,14,20-22H,12-13,15H2	STZQQINBQFSEJJ-UHFFFAOYSA-N	388530	US9944618, Compound ID No. 64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388530	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388530&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675691	404957173							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776343	CNC[C@@H]([C@@H](O)c1ccccc1[N+]([O-])=O)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H16Cl2N2O3/c1-19-9-12(10-6-7-13(17)14(18)8-10)16(21)11-4-2-3-5-15(11)20(22)23/h2-8,12,16,19,21H,9H2,1H3	MHQWTMHITCVCBY-UHFFFAOYSA-N	388531	US9944618, Compound ID No. 65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 19000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388531	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388531&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288677	404957174							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776349	CNCC(CCc1ccccc1)[C@H](O)c1ccccc1 |r|	InChI=1S/C18H23NO/c1-19-14-17(13-12-15-8-4-2-5-9-15)18(20)16-10-6-3-7-11-16/h2-11,17-20H,12-14H2,1H3	MOEHGFZIHNMYIW-UHFFFAOYSA-N	388532	US9944618, Compound ID No. 66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388532	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388532&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			146011491	404957175							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776355	CNC[C@@H]([C@H](OCc1nc(C)no1)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C24H25N3O2/c1-17-26-23(29-27-17)16-28-24(19-9-4-3-5-10-19)22(15-25-2)21-13-12-18-8-6-7-11-20(18)14-21/h3-14,22,24-25H,15-16H2,1-2H3	ABXMAAVUSZPZAU-UHFFFAOYSA-N	388533	US9944618, Compound ID No. 67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388533	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388533&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288679	404957176							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776364	CNCC(Cc1ccccc1O)c1ccc2ccccc2c1	InChI=1S/C20H21NO/c1-21-14-19(13-18-8-4-5-9-20(18)22)17-11-10-15-6-2-3-7-16(15)12-17/h2-12,19,21-22H,13-14H2,1H3	UUDREXTXTFFTKD-UHFFFAOYSA-N	388518	US9944618, Compound ID No. 69::US9944618, Compound ID No. 52	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9500							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388518	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388518&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288681	404957162							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776370	CNC[C@@H]([C@@H](O)c1ccccc1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H17Cl2NO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	RAPMQRUFYZBKQI-UHFFFAOYSA-N	388536	US9944618, Compound ID No. 70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 31000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388536	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388536&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675459	404957178							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776379	CNC[C@H]([C@H](O)c1ccccn1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H20N2O/c1-20-13-17(19(22)18-8-4-5-11-21-18)16-10-9-14-6-2-3-7-15(14)12-16/h2-12,17,19-20,22H,13H2,1H3	WWCABWLHQIWGCT-UHFFFAOYSA-N	388538	US9944618, Compound ID No. 99::US9944618, Compound ID No. 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388538&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288753	404957180							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776385	CNCC([C@H](O)c1ccccc1)c1ccc(F)c(Cl)c1 |r|	InChI=1S/C16H17ClFNO/c1-19-10-13(12-7-8-15(18)14(17)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	VQTDVJQKOKTVJM-UHFFFAOYSA-N	388539	US9944618, Compound ID No. 73	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 31000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388539	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388539&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118689233	404957181							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776391	CNCC(Cc1cccnc1)c1ccc2ccccc2c1	InChI=1S/C19H20N2/c1-20-14-19(11-15-5-4-10-21-13-15)18-9-8-16-6-2-3-7-17(16)12-18/h2-10,12-13,19-20H,11,14H2,1H3	ZBKRQGWGLHOYPX-UHFFFAOYSA-N	388514	US9944618, Compound ID No. 74::US9944618, Compound ID No. 48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388514	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388514&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288755	404957158							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776402	CNC[C@@H]([C@H](O)c1cccc(Br)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H16BrCl2NO/c1-20-9-13(10-5-6-14(18)15(19)8-10)16(21)11-3-2-4-12(17)7-11/h2-8,13,16,20-21H,9H2,1H3	NGXVLKNIKQVIQZ-UHFFFAOYSA-N	388542	US9944618, Compound ID No. 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388542	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388542&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675622	404957183							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776408	CN1CCO[C@@H]([C@H](C1)c1ccc2ccccc2c1)c1ccccc1 |r|	InChI=1S/C22H23NO/c1-23-13-14-24-22(18-8-3-2-4-9-18)21(16-23)20-12-11-17-7-5-6-10-19(17)15-20/h2-12,15,21-22H,13-14,16H2,1H3	ZHTDXMSHUPCRLP-UHFFFAOYSA-N	388543	US9944618, Compound ID No. 77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388543	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388543&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675492	404957184							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776413	CNC[C@H]([C@@H](O)c1ccccc1F)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20FNO/c1-22-13-18(20(23)17-8-4-5-9-19(17)21)16-11-10-14-6-2-3-7-15(14)12-16/h2-12,18,20,22-23H,13H2,1H3	SIHJLDGXFAZQND-UHFFFAOYSA-N	388544	US9944618, Compound ID No. 78	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388544	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388544&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288759	404957185							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776422	CNCC(Cc1cccnc1)c1ccc(Cl)c(Cl)c1	InChI=1S/C15H16Cl2N2/c1-18-10-13(7-11-3-2-6-19-9-11)12-4-5-14(16)15(17)8-12/h2-6,8-9,13,18H,7,10H2,1H3	OOCQXYIWPXQLSE-UHFFFAOYSA-N	388546	US9944618, Compound ID No. 80	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388546&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287681	404957187							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776431	CN(C)C[C@@H]([C@H](N)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C21H24N2/c1-23(2)15-20(21(22)17-9-4-3-5-10-17)19-13-12-16-8-6-7-11-18(16)14-19/h3-14,20-21H,15,22H2,1-2H3	UOYWGKDKOJANLM-UHFFFAOYSA-N	388548	US9944618, Compound ID No. 82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 19000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388548&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			68766103	404957189							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776437	CN(C)C[C@@H]([C@H](O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-22(2)15-20(21(23)17-9-4-3-5-10-17)19-13-12-16-8-6-7-11-18(16)14-19/h3-14,20-21,23H,15H2,1-2H3	NJZNJPXRRCEVDH-UHFFFAOYSA-N	388549	US9944618, Compound ID No. 83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4300							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388549	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388549&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			9974625	404957190							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776444	CNCC(C[C@H](O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-22-15-20(14-21(23)17-8-3-2-4-9-17)19-12-11-16-7-5-6-10-18(16)13-19/h2-13,20-23H,14-15H2,1H3	REWQWXUBFBJFJZ-UHFFFAOYSA-N	388551	US9944618, Compound ID No. 85	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388551	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388551&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134420059	404957192							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776450	CN(C)CC(C)(C(O)c1ccccc1)c1ccc2ccccc2c1	InChI=1S/C22H25NO/c1-22(16-23(2)3,21(24)18-10-5-4-6-11-18)20-14-13-17-9-7-8-12-19(17)15-20/h4-15,21,24H,16H2,1-3H3	WVMRNJPSSWNSQF-UHFFFAOYSA-N	388552	US9944618, Compound ID No. 86	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 850							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388552	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388552&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287683	404957193							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776456	CNC[C@@H]([C@H](N)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H22N2/c1-22-14-19(20(21)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-20,22H,14,21H2,1H3	FGDBXOANGGQWML-UHFFFAOYSA-N	388553	US9944618, Compound ID No. 87	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388553	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388553&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44156486	404957194							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776462	NC[C@H]([C@@H](O)c1ccccc1)c1ccc2ccccc2c1	InChI=1S/C19H19NO/c20-13-18(19(21)15-7-2-1-3-8-15)17-11-10-14-6-4-5-9-16(14)12-17/h1-12,18-19,21H,13,20H2	KLPCBCDMRUJYFL-UHFFFAOYSA-N	50069448	(1R,2R)-3-Amino-2-naphthalen-2-yl-1-phenyl-propan-1-ol; hydrochloride::CHEMBL539564::US9944618, Compound ID No. 88	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 23000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069448	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069448&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			10107559	103963509		CHEMBL539564					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776468	CN(C)C[C@@H]([C@H](OCCO)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C23H27NO2/c1-24(2)17-22(21-13-12-18-8-6-7-11-20(18)16-21)23(26-15-14-25)19-9-4-3-5-10-19/h3-13,16,22-23,25H,14-15,17H2,1-2H3	BFGINKQURNHWAV-UHFFFAOYSA-N	388555	US9944618, Compound ID No. 89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6600							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388555&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287684	404957196							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776474	CNCC(Cc1ccccc1CO)c1ccc2ccccc2c1	InChI=1S/C21H23NO/c1-22-14-21(13-18-8-4-5-9-20(18)15-23)19-11-10-16-6-2-3-7-17(16)12-19/h2-12,21-23H,13-15H2,1H3	BUZAYDYQPINNKR-UHFFFAOYSA-N	388468	US9944618, Compound ID No. 90::US9944618, Compound ID No. 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388468	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388468&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288291	404957114							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776479	NCC([C@@H](O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H19NO/c20-13-18(19(21)15-7-2-1-3-8-15)17-11-10-14-6-4-5-9-16(14)12-17/h1-12,18-19,21H,13,20H2	KLPCBCDMRUJYFL-UHFFFAOYSA-N	388557	US9944618, Compound ID No. 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 31000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388557	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388557&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			69454235	404957197							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776483	CNC[C@@H]([C@H](O)c1cncc(OC)c1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H22N2O2/c1-21-13-19(20(23)17-10-18(24-2)12-22-11-17)16-8-7-14-5-3-4-6-15(14)9-16/h3-12,19-21,23H,13H2,1-2H3	ZYQBVZPSYAIUDW-UHFFFAOYSA-N	388558	US9944618, Compound ID No. 92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388558	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388558&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287685	404957198							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776489	CNC[C@H](C[C@H](O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C21H23NO/c1-22-15-20(14-21(23)17-8-3-2-4-9-17)19-12-11-16-7-5-6-10-18(16)13-19/h2-13,20-23H,14-15H2,1H3	REWQWXUBFBJFJZ-UHFFFAOYSA-N	388559	US9944618, Compound ID No. 93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388559	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388559&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675439	404957199							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776494	CNC[C@@H]([C@@H](O)c1cccc(NC(C)=O)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C18H20Cl2N2O2/c1-11(23)22-14-5-3-4-13(8-14)18(24)15(10-21-2)12-6-7-16(19)17(20)9-12/h3-9,15,18,21,24H,10H2,1-2H3,(H,22,23)	YVLHQFZWDLUAGE-UHFFFAOYSA-N	388560	US9944618, Compound ID No. 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388560	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388560&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287746	404957200							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776500	NC[C@@H]([C@@H](O)c1ccncc1Cl)c1ccc2ccccc2c1 |r|	InChI=1S/C18H17ClN2O/c19-17-11-21-8-7-15(17)18(22)16(10-20)14-6-5-12-3-1-2-4-13(12)9-14/h1-9,11,16,18,22H,10,20H2	MHFVKTJHLKVXQQ-UHFFFAOYSA-N	388561	US9944618, Compound ID No. 95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388561	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388561&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287747	404957201							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776506	CNC[C@H]([C@H](O)c1ccccc1F)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20FNO/c1-22-13-18(20(23)17-8-4-5-9-19(17)21)16-11-10-14-6-2-3-7-15(14)12-16/h2-12,18,20,22-23H,13H2,1H3	SIHJLDGXFAZQND-UHFFFAOYSA-N	388562	US9944618, Compound ID No. 96	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388562	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388562&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675641	404957202							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776512	CNC[C@@H]([C@@H](O)c1ccccc1SC)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C17H19Cl2NOS/c1-20-10-13(11-7-8-14(18)15(19)9-11)17(21)12-5-3-4-6-16(12)22-2/h3-9,13,17,20-21H,10H2,1-2H3	HZSJACIMFDUAAV-UHFFFAOYSA-N	388563	US9944618, Compound ID No. 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388563	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388563&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287749	404957203							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776518	CNC[C@H]([C@H](O)c1cccc(NC(C)=O)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C18H20Cl2N2O2/c1-11(23)22-14-5-3-4-13(8-14)18(24)15(10-21-2)12-6-7-16(19)17(20)9-12/h3-9,15,18,21,24H,10H2,1-2H3,(H,22,23)	YVLHQFZWDLUAGE-UHFFFAOYSA-N	388564	US9944618, Compound ID No. 98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388564	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388564&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675620	404957204							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776524	CNC[C@H]([C@H](O)c1ccccn1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H20N2O/c1-20-13-17(19(22)18-8-4-5-11-21-18)16-10-9-14-6-2-3-7-15(14)12-16/h2-12,17,19-20,22H,13H2,1H3	WWCABWLHQIWGCT-UHFFFAOYSA-N	388538	US9944618, Compound ID No. 99::US9944618, Compound ID No. 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 33000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388538	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388538&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86288753	404957180							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776530	CNC[C@@H]([C@@H](O)c1ccccc1-c1cccs1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C20H19Cl2NOS/c1-23-12-16(13-8-9-17(21)18(22)11-13)20(24)15-6-3-2-5-14(15)19-7-4-10-25-19/h2-11,16,20,23-24H,12H2,1H3	DTANZUXBNYHQGY-UHFFFAOYSA-N	388566	US9944618, Compound ID No. 100	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388566	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388566&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287751	404957205							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776581	CNC[C@H]([C@@H](O)c1ccccc1)c1ccc(Br)c(Cl)c1 |r|	InChI=1S/C16H17BrClNO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	YYXLUZNBTYTCJI-UHFFFAOYSA-N	388576	US9944618, Compound ID No. 110	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388576	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388576&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287819	404957214							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776597	CNC[C@H]([C@@H](O)c1ccccc1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H17Cl2NO/c1-19-10-13(12-7-8-14(17)15(18)9-12)16(20)11-5-3-2-4-6-11/h2-9,13,16,19-20H,10H2,1H3	RAPMQRUFYZBKQI-UHFFFAOYSA-N	388579	US9944618, Compound ID No. 114	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388579	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388579&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675546	404957217							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776616	NC[C@H](C(O)c1ccncc1Cl)c1ccc2ccccc2c1 |r|	InChI=1S/C18H17ClN2O/c19-17-11-21-8-7-15(17)18(22)16(10-20)14-6-5-12-3-1-2-4-13(12)9-14/h1-9,11,16,18,22H,10,20H2	MHFVKTJHLKVXQQ-UHFFFAOYSA-N	388583	US9944618, Compound ID No. 118	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 24000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388583	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388583&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118689236	404957221							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776679	CNCC(Cc1ccccc1OC)c1ccc2ccccc2c1	InChI=1S/C21H23NO/c1-22-15-20(14-19-9-5-6-10-21(19)23-2)18-12-11-16-7-3-4-8-17(16)13-18/h3-13,20,22H,14-15H2,1-2H3	MRAZBVXMLFFLEZ-UHFFFAOYSA-N	388523	US9944618, Compound ID No. 132::US9944618, Compound ID No. 57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4700							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388523	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388523&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117604895	404957166							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776688	CNCC(Cc1ccccc1C)c1ccc2ccccc2c1	InChI=1S/C21H23N/c1-16-7-3-4-9-18(16)13-21(15-22-2)20-12-11-17-8-5-6-10-19(17)14-20/h3-12,14,21-22H,13,15H2,1-2H3	GIXNEGGWWYHJGX-UHFFFAOYSA-N	388505	US9944618, Compound ID No. 134::US9944618, Compound ID No. 39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6200							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388505	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388505&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675480	404957150							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776694	CN(C)C[C@@H]([C@H](O)c1cccs1)c1ccc2ccccc2c1 |r|	InChI=1S/C19H21NOS/c1-20(2)13-17(19(21)18-8-5-11-22-18)16-10-9-14-6-3-4-7-15(14)12-16/h3-12,17,19,21H,13H2,1-2H3	JJMQUHWUNDSOBS-UHFFFAOYSA-N	388599	US9944618, Compound ID No. 135	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388599	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388599&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118689239	404957235							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776700	CNC[C@@H]([C@H](OC)c1ccc2OCOc2c1)c1ccc2ccccc2c1 |r|	InChI=1S/C22H23NO3/c1-23-13-19(17-8-7-15-5-3-4-6-16(15)11-17)22(24-2)18-9-10-20-21(12-18)26-14-25-20/h3-12,19,22-23H,13-14H2,1-2H3	BZMNAEZFJDLGAL-UHFFFAOYSA-N	388600	US9944618, Compound ID No. 136	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388600&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118689240	404957236							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776706	NCC(Cc1ccccc1F)c1ccc2ccccc2c1	InChI=1S/C19H18FN/c20-19-8-4-3-7-17(19)12-18(13-21)16-10-9-14-5-1-2-6-15(14)11-16/h1-11,18H,12-13,21H2	VIVXWRRXKKDPKC-UHFFFAOYSA-N	388601	US9944618, Compound ID No. 137	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388601	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388601&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675572	404957237							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776717	CNCC(Cc1ccc(C)s1)c1ccc2ccccc2c1	InChI=1S/C19H21NS/c1-14-7-10-19(21-14)12-18(13-20-2)17-9-8-15-5-3-4-6-16(15)11-17/h3-11,18,20H,12-13H2,1-2H3	ZTPBYUKSIHXSEW-UHFFFAOYSA-N	388603	US9944618, Compound ID No. 139	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388603	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388603&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			117605014	404957239							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776723	CNC[C@H](Cc1ccccc1O)c1ccc2ccccc2c1 |r|	InChI=1S/C20H21NO/c1-21-14-19(13-18-8-4-5-9-20(18)22)17-11-10-15-6-2-3-7-16(15)12-17/h2-12,19,21-22H,13-14H2,1H3	UUDREXTXTFFTKD-UHFFFAOYSA-N	388604	US9944618, Compound ID No. 140	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388604&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675581	404957240							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776739	CNC[C@@H]([C@H](O)c1ccc2OCCOc2c1)c1ccc2ccccc2c1 |r|	InChI=1S/C22H23NO3/c1-23-14-19(17-7-6-15-4-2-3-5-16(15)12-17)22(24)18-8-9-20-21(13-18)26-11-10-25-20/h2-9,12-13,19,22-24H,10-11,14H2,1H3	SKNYTQXZSKBQCN-UHFFFAOYSA-N	388607	US9944618, Compound ID No. 143	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388607	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388607&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675624	404957243							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776745	CNC[C@H]([C@@H](O)c1cccs1)c1ccc2ccccc2c1 |r|	InChI=1S/C18H19NOS/c1-19-12-16(18(20)17-7-4-10-21-17)15-9-8-13-5-2-3-6-14(13)11-15/h2-11,16,18-20H,12H2,1H3	PKZICZJQJAOMKU-UHFFFAOYSA-N	388608	US9944618, Compound ID No. 144	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388608&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675509	404957244							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776751	CNC[C@H]([C@@H](O)c1ccc2OCCOc2c1)c1ccc2ccccc2c1 |r|	InChI=1S/C22H23NO3/c1-23-14-19(17-7-6-15-4-2-3-5-16(15)12-17)22(24)18-8-9-20-21(13-18)26-11-10-25-20/h2-9,12-13,19,22-24H,10-11,14H2,1H3	SKNYTQXZSKBQCN-UHFFFAOYSA-N	388609	US9944618, Compound ID No. 145	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388609	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388609&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			134420033	404957245							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776757	CNC[C@@H]([C@H](Cl)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H20ClN/c1-22-14-19(20(21)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-20,22H,14H2,1H3	LZILTVHXOJJKON-UHFFFAOYSA-N	388610	US9944618, Compound ID No. 146	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388610	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388610&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44156359	404957246							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776775	CNC[C@@H]([C@H](O)c1cccc(I)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H16Cl2INO/c1-20-9-13(10-5-6-14(17)15(18)8-10)16(21)11-3-2-4-12(19)7-11/h2-8,13,16,20-21H,9H2,1H3	YMLQTIHIVWNNAV-UHFFFAOYSA-N	388615	US9944618, Compound ID No. 151	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388615	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388615&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675711	404957250							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776786	CNC[C@H]([C@@H](O)c1ccsc1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C14H15Cl2NOS/c1-17-7-11(14(18)10-4-5-19-8-10)9-2-3-12(15)13(16)6-9/h2-6,8,11,14,17-18H,7H2,1H3	OBLQTDRIHYWTHA-UHFFFAOYSA-N	388572	US9944618, Compound ID No. 153::US9944618, Compound ID No. 106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1600							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388572	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388572&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			86287816	404957210							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776792	CNC[C@H]([C@@H](O)c1cccc(SC)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C17H19Cl2NOS/c1-20-10-14(11-6-7-15(18)16(19)9-11)17(21)12-4-3-5-13(8-12)22-2/h3-9,14,17,20-21H,10H2,1-2H3	YDSDFUFLGLKXSJ-UHFFFAOYSA-N	388585	US9944618, Compound ID No. 154::US9944618, Compound ID No. 120	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2200							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388585	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388585&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675579	404957223							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776803	CNC[C@@H]([C@H](O)c1ccccc1SC)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C17H19Cl2NOS/c1-20-10-13(11-7-8-14(18)15(19)9-11)17(21)12-5-3-4-6-16(12)22-2/h3-9,13,17,20-21H,10H2,1-2H3	HZSJACIMFDUAAV-UHFFFAOYSA-N	388620	US9944618, Compound ID No. 156	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388620	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388620&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675540	404957253							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776814	CCc1ccccc1[C@@H](O)[C@H](CNC)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C18H21Cl2NO/c1-3-12-6-4-5-7-14(12)18(22)15(11-21-2)13-8-9-16(19)17(20)10-13/h4-10,15,18,21-22H,3,11H2,1-2H3	JATLLLBZJVYCFM-UHFFFAOYSA-N	388622	US9944618, Compound ID No. 158	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4400							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388622	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388622&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675523	404957255							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776825	CNC[C@@H]([C@H](O)c1ccccc1OC)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C17H19Cl2NO2/c1-20-10-13(11-7-8-14(18)15(19)9-11)17(21)12-5-3-4-6-16(12)22-2/h3-9,13,17,20-21H,10H2,1-2H3	UXTWRXZFUNWDBN-UHFFFAOYSA-N	388624	US9944618, Compound ID No. 160	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388624	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388624&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675705	404957257							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776846	CNC[C@@H]([C@H](O)c1ccccc1I)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H16Cl2INO/c1-20-9-12(10-6-7-13(17)14(18)8-10)16(21)11-4-2-3-5-15(11)19/h2-8,12,16,20-21H,9H2,1H3	NHDSYXZEDKBTPN-UHFFFAOYSA-N	388628	US9944618, Compound ID No. 164	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4100							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388628	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388628&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675566	404957261							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776852	CNC[C@@H]([C@@H](O)c1cccc(I)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H16Cl2INO/c1-20-9-13(10-5-6-14(17)15(18)8-10)16(21)11-3-2-4-12(19)7-11/h2-8,13,16,20-21H,9H2,1H3	YMLQTIHIVWNNAV-UHFFFAOYSA-N	388629	US9944618, Compound ID No. 165	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388629	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388629&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675628	404957262							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776863	CNC[C@@H]([C@H](O)c1cccc(OC)n1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C16H18Cl2N2O2/c1-19-9-11(10-6-7-12(17)13(18)8-10)16(21)14-4-3-5-15(20-14)22-2/h3-8,11,16,19,21H,9H2,1-2H3	HWZPXVTVANPWNG-UHFFFAOYSA-N	388631	US9944618, Compound ID No. 167	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388631	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388631&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675720	404957264							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776889	CNC[C@H]([C@@H](OC)c1cccc(NS(=O)(=O)C(F)(F)F)c1)c1ccc(Cl)c(Cl)c1 |r|	InChI=1S/C18H19Cl2F3N2O3S/c1-24-10-14(11-6-7-15(19)16(20)9-11)17(28-2)12-4-3-5-13(8-12)25-29(26,27)18(21,22)23/h3-9,14,17,24-25H,10H2,1-2H3	BXBUTKPGTGJGTQ-UHFFFAOYSA-N	388636	US9944618, Compound ID No. 172	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4700							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388636	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388636&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118675684	404957269							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776895	CNC[C@@H]([C@H](O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H21NO/c1-21-14-19(20(22)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-22H,14H2,1H3	RSZGIFQDUIROGN-UHFFFAOYSA-N	388637	US9944618, Compound ID No. 173::AZD1858 MCJ001- SS	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8800							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388637&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			20631904	404957270							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776899	CNCCCN1c2ccccc2CCc3c1cccc3	InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	HCYAFALTSJYZDH-UHFFFAOYSA-N	35229	Desmethylimipramine::3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine::monodemethylimipramine::Desipramin::5-(gamma-methylaminopropyl)iminodibenzyl::norimipramine::CHEMBL72::DESIPRAMINE HYDROCHLORIDE::demethylimipramine::N-(3-methylaminopropyl)iminobibenzyl::DMI::Desipramine::US9944618, Compound ID No. 174	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35229	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35229&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	DSM	2QB4,2QJU,7Q19,7Q2N,7Q2O,7Q2P,8HFI,8WGR	2995	85753308		CHEMBL72	DB01151		C06943		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776903	c1ccc(cc1)CCCN2CCN(CC2)CCOC(c3ccc(cc3)F)c4ccc(cc4)F	InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	NAUWTFJOPJWYOT-UHFFFAOYSA-N	22165	Vanoxerine::CHEMBL542933::GBR-12909::CHEMBL543876::CHEMBL281594::1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::GBR 12909::NCGC00015300::US9944618, Compound ID No. 175	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 470							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22165	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22165&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	A1D5S	8Y2F,9JKM,9KDH	3455	49845980		CHEMBL153260CHEMBL281594CHEMBL543876CHEMBL542933					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776907	CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1	InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3	SNPPWIUOZRMYNY-UHFFFAOYSA-N	50048392	BUPROPION HYDROCHLORIDE::CHEMBL894::2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::US9944618, Compound ID No. 176	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 69000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048392	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048392&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			444	103978858		CHEMBL894	DB01156		C06860		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776917	Clc1ccc(cc1Cl)[C@@]12C[C@@H]1CNC2 |r|	InChI=1S/C11H11Cl2N/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11/h1-3,8,14H,4-6H2	BSMNRYCSBFHEMQ-UHFFFAOYSA-N	50386812	DOV 21947::DOV-21947::EB-1010::AMITIFADINE HYDROCHLORIDE::US9944618, Compound ID No. 179	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386812&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11658655	160865895							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776923	CNC[C@H]([C@H](O)c1ccccc1)c1ccc2ccccc2c1 |r|	InChI=1S/C20H21NO/c1-21-14-19(20(22)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-22H,14H2,1H3	RSZGIFQDUIROGN-UHFFFAOYSA-N	388644	US9944618, Compound ID No. 180::PRC-200 isomer	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32000							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=388644	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=388644&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			20631902	404957277							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
776930	c1cc(ccc1[C@@H]2CCNC[C@H]2COc3ccc4c(c3)OCO4)F	InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2	AHOUBRCZNHFOSL-UHFFFAOYSA-N	22416	PAROXETINE::CHEMBL490::(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::[3H]Paroxetine::US09969700, Paroxetine::US9944618, Compound ID No. 182	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5400							US Patent		10.7270/Q26D5WBR		aid1798757	US9944618	Richelson, E; Fauq, AH; Carlier, P; Monceaux, CJ	4/17/2018	3/12/2020	Mayo Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22416	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22416&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	8PR	3V5W,4JLT,4L9I,4MM4,5I6X,6AWN,6DZW,6F6I,6VRH,7OIH	43815	49846231		CHEMBL490	DB00715		C07415		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786582	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US9968610, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786583	FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ccc12)c1ccc(Cl)cn1	InChI=1S/C18H19ClF2N6/c19-12-1-2-15(23-9-12)18(20,21)10-27-7-4-13(5-8-27)26-17-14-3-6-22-16(14)24-11-25-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,22,24,25,26)	QOTIEMUIZUBYME-UHFFFAOYSA-N	287587	US9567341, Compound C-3::US9968610, Compound C-3::US10420768, Compound C-3::US11752155, Compound C-3A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7000							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287587&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938577	378171154							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786584	Cc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H22F2N6/c1-13-2-3-16(23-10-13)19(20,21)11-27-8-5-14(6-9-27)26-18-15-4-7-22-17(15)24-12-25-18/h2-4,7,10,12,14H,5-6,8-9,11H2,1H3,(H2,22,24,25,26)	RYFZFQVKNZTNST-UHFFFAOYSA-N	287588	US9567341, Compound C-4::US9968610, Compound C-4::US10420768, Compound C-4::US11752155, Compound C-4A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11400							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938581	378171155							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786585	FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H19F5N6/c20-18(21,15-2-1-12(9-26-15)19(22,23)24)10-30-7-4-13(5-8-30)29-17-14-3-6-25-16(14)27-11-28-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,25,27,28,29)	NTMXMRKJKVFRLP-UHFFFAOYSA-N	287589	US9567341, Compound C-5::US9968610, Compound C-5::US10420768, Compound C-5::US11752155, Compound C-5A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9500							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287589&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559717	378171156							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786586	Cc1cnc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C18H21F2N7/c1-12-8-23-15(9-22-12)18(19,20)10-27-6-3-13(4-7-27)26-17-14-2-5-21-16(14)24-11-25-17/h2,5,8-9,11,13H,3-4,6-7,10H2,1H3,(H2,21,24,25,26)	OLLWXMDGFDGOBR-UHFFFAOYSA-N	287594	US9567341, Compound C-230::US9968610, Compound C-230::US10420768, Compound C-230::US11752155, Compound C-230A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13800							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938588	378171161							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786587	FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-2-15(26-9-12)19(22,23)24)10-30-7-4-13(5-8-30)29-17-14-3-6-25-16(14)27-11-28-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,25,27,28,29)	CSLAFKNTMSZKMA-UHFFFAOYSA-N	287596	US9567341, Compound C-127::US9968610, Compound C-127::US10420768, Compound C-127::US11752155, Compound C-127A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6000							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287596&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938509	378171163							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786588	Cc1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H22F2N6/c1-13-2-3-14(10-23-13)19(20,21)11-27-8-5-15(6-9-27)26-18-16-4-7-22-17(16)24-12-25-18/h2-4,7,10,12,15H,5-6,8-9,11H2,1H3,(H2,22,24,25,26)	WFXULSHSKBXRPA-UHFFFAOYSA-N	287597	US9567341, Compound C-128::US9968610, Compound C-128::US10420768, Compound C-128::US11752155, Compound C-128A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 28000							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938568	378171164							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
786589	Fc1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H20F3N5/c20-14-3-1-13(2-4-14)19(21,22)11-27-9-6-15(7-10-27)26-18-16-5-8-23-17(16)24-12-25-18/h1-5,8,12,15H,6-7,9-11H2,(H2,23,24,25,26)	ZPTGKQWXVKFGAF-UHFFFAOYSA-N	287604	US9567341, Compound C-175::US9968610, Compound C-175::US10420768, Compound C-175::US11752155, Compound C-175A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2JD505V		aid1798955	US9968610	Shapiro, G	5/15/2018	4/6/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287604&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938512	378171171							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792949	Cc1nc(C)n(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C13H13ClN6/c1-9-15-10(2)19(17-9)7-12-8-20(18-16-12)13-5-3-11(14)4-6-13/h3-6,8H,7H2,1-2H3	AQLRWJVRJUSCJS-UHFFFAOYSA-N	396794	US9981950, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396794&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71970823	405266862							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792950	CCCc1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C14H15ClN6/c1-2-3-14-16-10-17-21(14)9-12-8-20(19-18-12)13-6-4-11(15)5-7-13/h4-8,10H,2-3,9H2,1H3	IWNKFQATMQELSV-UHFFFAOYSA-N	396795	US9981950, Example 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396795&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870145	405266863							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792951	CCCc1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C14H15ClN6/c1-2-3-14-16-10-20(18-14)8-12-9-21(19-17-12)13-6-4-11(15)5-7-13/h4-7,9-10H,2-3,8H2,1H3	RZCIDOWEQOSVFU-UHFFFAOYSA-N	396796	US9981950, Example 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396796&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870129	405266864							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792952	CC(C)c1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C14H15ClN6/c1-10(2)14-16-9-20(18-14)7-12-8-21(19-17-12)13-5-3-11(15)4-6-13/h3-6,8-10H,7H2,1-2H3	PWVKLWNAGDSQLN-UHFFFAOYSA-N	396797	US9981950, Example 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396797&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870132	405266865							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792953	CCc1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C13H13ClN6/c1-2-13-15-9-16-20(13)8-11-7-19(18-17-11)12-5-3-10(14)4-6-12/h3-7,9H,2,8H2,1H3	VKYQAXYBRHJTAL-UHFFFAOYSA-N	396798	US9981950, Example 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396798&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870177	405266866							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792954	CCc1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C13H13ClN6/c1-2-13-15-9-19(17-13)7-11-8-20(18-16-11)12-5-3-10(14)4-6-12/h3-6,8-9H,2,7H2,1H3	HRQZQCFVMLFYSB-UHFFFAOYSA-N	396799	US9981950, Example 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396799&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870068	405266867							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792955	CC(C)c1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C14H15ClN6/c1-10(2)14-16-9-17-21(14)8-12-7-20(19-18-12)13-5-3-11(15)4-6-13/h3-7,9-10H,8H2,1-2H3	DSHSWXIKZMKFMX-UHFFFAOYSA-N	396800	US9981950, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396800&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870062	405266868							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792956	Cc1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H11ClN6/c1-9-14-8-15-18(9)6-11-7-19(17-16-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	AMYCLBLRVRIJGO-UHFFFAOYSA-N	396801	US9981950, Example 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 14300							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396801&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870157	405266869							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792957	Cc1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C12H11ClN6/c1-9-14-8-18(16-9)6-11-7-19(17-15-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	TXAHJZVCNFFEJR-UHFFFAOYSA-N	396802	US9981950, Example 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396802&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870118	405266870							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792958	Clc1ccc(cc1)-n1cc(Cn2nc(nc2C2CC2)C2CC2)nn1	InChI=1S/C17H17ClN6/c18-13-5-7-15(8-6-13)23-9-14(20-22-23)10-24-17(12-3-4-12)19-16(21-24)11-1-2-11/h5-9,11-12H,1-4,10H2	LVBHPJLNQRYDTB-UHFFFAOYSA-N	396803	US9981950, Example 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396803&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870111	405266871							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792959	Clc1ccc(cc1)-n1cc(Cn2ncnc2C2CCC2)nn1	InChI=1S/C15H15ClN6/c16-12-4-6-14(7-5-12)21-8-13(19-20-21)9-22-15(17-10-18-22)11-2-1-3-11/h4-8,10-11H,1-3,9H2	QKBPERVPIARHRO-UHFFFAOYSA-N	396804	US9981950, Example 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396804&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870078	405266872							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792960	Clc1ccc(cc1)-n1cc(Cn2cnc(n2)C2CCC2)nn1	InChI=1S/C15H15ClN6/c16-12-4-6-14(7-5-12)22-9-13(18-20-22)8-21-10-17-15(19-21)11-2-1-3-11/h4-7,9-11H,1-3,8H2	CWHJIHOWGGKGEA-UHFFFAOYSA-N	396805	US9981950, Example 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870140	405266873							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792961	Clc1ccc(cc1)-n1cc(Cn2cnc(n2)C2CC2)nn1	InChI=1S/C14H13ClN6/c15-11-3-5-13(6-4-11)21-8-12(17-19-21)7-20-9-16-14(18-20)10-1-2-10/h3-6,8-10H,1-2,7H2	FYLLXYYSVQPAKZ-UHFFFAOYSA-N	396806	US9981950, Example 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396806&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870149	405266874							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792962	Clc1ccc(cc1)-n1cc(Cn2ncnc2C2CCCC2)nn1	InChI=1S/C16H17ClN6/c17-13-5-7-15(8-6-13)22-9-14(20-21-22)10-23-16(18-11-19-23)12-3-1-2-4-12/h5-9,11-12H,1-4,10H2	FDBRNTUVWGVIAY-UHFFFAOYSA-N	396807	US9981950, Example 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12500							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870152	405266875							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792963	Clc1ccc(cc1)-n1cc(Cn2cnc(n2)C2CCCC2)nn1	InChI=1S/C16H17ClN6/c17-13-5-7-15(8-6-13)23-10-14(19-21-23)9-22-11-18-16(20-22)12-3-1-2-4-12/h5-8,10-12H,1-4,9H2	AQRMSNKJMMOWNY-UHFFFAOYSA-N	396808	US9981950, Example 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396808&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870148	405266876							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792964	Clc1ccc(cc1)-n1cc(Cn2ncnc2C2CC2)nn1	InChI=1S/C14H13ClN6/c15-11-3-5-13(6-4-11)20-7-12(18-19-20)8-21-14(10-1-2-10)16-9-17-21/h3-7,9-10H,1-2,8H2	OETSVHHBHCIQTP-UHFFFAOYSA-N	396809	US9981950, Example 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870124	405266877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792965	FC(F)(F)c1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C12H8ClF3N6/c13-8-1-3-10(4-2-8)22-6-9(18-20-22)5-21-7-17-11(19-21)12(14,15)16/h1-4,6-7H,5H2	CAIRHTFTLPIFQU-UHFFFAOYSA-N	396810	US9981950, Example 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396810&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870076	405266878							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792966	CCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C15H16ClN5/c1-2-3-15-17-8-9-20(15)10-13-11-21(19-18-13)14-6-4-12(16)5-7-14/h4-9,11H,2-3,10H2,1H3	AYJDATHUPMMOSP-UHFFFAOYSA-N	396811	US9981950, Example 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46.6							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396811&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870063	405266879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792967	CC(C)(C)c1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C15H17ClN6/c1-15(2,3)14-17-10-18-22(14)9-12-8-21(20-19-12)13-6-4-11(16)5-7-13/h4-8,10H,9H2,1-3H3	NNARYJXWYNWMSY-UHFFFAOYSA-N	396812	US9981950, Example 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396812&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870133	405266880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792968	CC(C)(C)c1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C15H17ClN6/c1-15(2,3)14-17-10-21(19-14)8-12-9-22(20-18-12)13-6-4-11(16)5-7-13/h4-7,9-10H,8H2,1-3H3	WTTBNWBKWZDRPV-UHFFFAOYSA-N	396813	US9981950, Example 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396813&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870151	405266881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792969	Cc1nc(C2CCC2)n(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C16H17ClN6/c1-11-18-16(12-3-2-4-12)23(20-11)10-14-9-22(21-19-14)15-7-5-13(17)6-8-15/h5-9,12H,2-4,10H2,1H3	KTERBHGAOPMQME-UHFFFAOYSA-N	396814	US9981950, Example 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396814&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870178	405266882							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792970	Cc1nc(nn1Cc1cn(nn1)-c1ccc(Cl)cc1)C1CCC1	InChI=1S/C16H17ClN6/c1-11-18-16(12-3-2-4-12)20-22(11)9-14-10-23(21-19-14)15-7-5-13(17)6-8-15/h5-8,10,12H,2-4,9H2,1H3	BGVIDOSBQYMVSL-UHFFFAOYSA-N	396815	US9981950, Example 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396815&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870154	405266883							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792971	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C15H16ClN5/c1-11(2)15-17-7-8-20(15)9-13-10-21(19-18-13)14-5-3-12(16)4-6-14/h3-8,10-11H,9H2,1-2H3	NRWRQBPXPZXDGL-UHFFFAOYSA-N	396816	US9981950, Example 23	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 77.4							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396816&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870080	405266884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792972	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C13H12ClN5/c1-10-15-6-7-18(10)8-12-9-19(17-16-12)13-4-2-11(14)3-5-13/h2-7,9H,8H2,1H3	OCWFBNMIXTWOIS-UHFFFAOYSA-N	396817	US9981950, Example 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 38.4							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396817&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870164	405266885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792973	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C14H14ClN5/c1-2-14-16-7-8-19(14)9-12-10-20(18-17-12)13-5-3-11(15)4-6-13/h3-8,10H,2,9H2,1H3	UHCWOUZOICIRGT-UHFFFAOYSA-N	396818	US9981950, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25.8							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396818&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870095	405266886							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792974	Clc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H9Cl2N5/c13-9-1-3-11(4-2-9)19-8-10(16-17-19)7-18-6-5-15-12(18)14/h1-6,8H,7H2	IVDHBJSENGBWTH-UHFFFAOYSA-N	396819	US9981950, Example 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9930							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396819&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870174	405266887							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792975	CCCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C16H18ClN5/c1-2-3-4-16-18-9-10-21(16)11-14-12-22(20-19-14)15-7-5-13(17)6-8-15/h5-10,12H,2-4,11H2,1H3	CEAOOXKEMXDLAB-UHFFFAOYSA-N	396820	US9981950, Example 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 38.9							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870108	405266888							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792976	OCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C13H12ClN5O/c14-10-1-3-12(4-2-10)19-8-11(16-17-19)7-18-6-5-15-13(18)9-20/h1-6,8,20H,7,9H2	MVPGLWBEKNSVHN-UHFFFAOYSA-N	396821	US9981950, Example 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 573							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396821&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870158	405266889							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792977	Clc1ccc(cc1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H14ClN5/c16-12-3-5-14(6-4-12)21-10-13(18-19-21)9-20-8-7-17-15(20)11-1-2-11/h3-8,10-11H,1-2,9H2	UCXUHYULIWVCHH-UHFFFAOYSA-N	396822	US9981950, Example 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 95.8							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396822&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870091	405266890							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792978	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C16H18ClN5/c1-16(2,3)15-18-8-9-21(15)10-13-11-22(20-19-13)14-6-4-12(17)5-7-14/h4-9,11H,10H2,1-3H3	KHTCVPAURHYMJW-UHFFFAOYSA-N	396823	US9981950, Example 30::2-tert-butyl-1H- imidazole 4-(2-tert-Butyl-imidazol-1-ylmethyl)-1-(4-chloro- phenyl)-1H-[1,2,3]triazole	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7200							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396823&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870163	405266891							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792979	Cc1nncn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H11ClN6/c1-9-15-14-8-18(9)6-11-7-19(17-16-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	LMZPNUTXBLCHOF-UHFFFAOYSA-N	396824	US9981950, Example 31::2-methyl-1H- imidazole 1-(4-Chloro-phenyl)-4-(3-methyl-[1,2,4]triazol-4- ylmethyl)-1H-[1,2,3]triazole	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870102	405266892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792980	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C13H11Cl2N5/c1-9-16-4-5-19(9)7-10-8-20(18-17-10)11-2-3-12(14)13(15)6-11/h2-6,8H,7H2,1H3	ZZKGILMYXMDXEH-UHFFFAOYSA-N	396825	US9981950, Example 32	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.92							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396825&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870084	405266893							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792981	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C14H13Cl2N5/c1-2-14-17-5-6-20(14)8-10-9-21(19-18-10)11-3-4-12(15)13(16)7-11/h3-7,9H,2,8H2,1H3	ACNAPZHYUZOZJN-UHFFFAOYSA-N	396826	US9981950, Example 33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.65							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396826&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870147	405266894							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792982	CCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C15H15Cl2N5/c1-2-3-15-18-6-7-21(15)9-11-10-22(20-19-11)12-4-5-13(16)14(17)8-12/h4-8,10H,2-3,9H2,1H3	VBCLULJZISPDRO-UHFFFAOYSA-N	396827	US9981950, Example 34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.67							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396827&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870114	405266895							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792983	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C15H15Cl2N5/c1-10(2)15-18-5-6-21(15)8-11-9-22(20-19-11)12-3-4-13(16)14(17)7-12/h3-7,9-10H,8H2,1-2H3	AJGOWAAIQPCIPM-UHFFFAOYSA-N	396828	US9981950, Example 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.40							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870155	405266896							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792984	Clc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13Cl2N5/c16-13-4-3-12(7-14(13)17)22-9-11(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	IEGRHOUALWXAMI-UHFFFAOYSA-N	396829	US9981950, Example 36	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17.9							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396829&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870167	405266897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792985	CCCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C16H17Cl2N5/c1-2-3-4-16-19-7-8-22(16)10-12-11-23(21-20-12)13-5-6-14(17)15(18)9-13/h5-9,11H,2-4,10H2,1H3	FABOZFZSWJBLAK-UHFFFAOYSA-N	396830	US9981950, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6.84							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396830&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870184	405266898							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792986	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C16H17Cl2N5/c1-16(2,3)15-19-6-7-22(15)9-11-10-23(21-20-11)12-4-5-13(17)14(18)8-12/h4-8,10H,9H2,1-3H3	ABOXKYVSSWHNON-UHFFFAOYSA-N	396831	US9981950, Example 38	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 526							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870101	405266899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792987	Clc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CCC2)nn1	InChI=1S/C16H15Cl2N5/c17-14-5-4-13(8-15(14)18)23-10-12(20-21-23)9-22-7-6-19-16(22)11-2-1-3-11/h4-8,10-11H,1-3,9H2	YUDVHEROTXDJBH-UHFFFAOYSA-N	396832	US9981950, Example 39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.58							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396832&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870109	405266900							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792988	OCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C14H13Cl2N5O/c15-12-2-1-11(7-13(12)16)21-9-10(18-19-21)8-20-5-4-17-14(20)3-6-22/h1-2,4-5,7,9,22H,3,6,8H2	HRJGAGOKRFPCOH-UHFFFAOYSA-N	396833	US9981950, Example 40	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17.2							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396833&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870119	405266901							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792989	FCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C14H12Cl2FN5/c15-12-2-1-11(7-13(12)16)22-9-10(19-20-22)8-21-6-5-18-14(21)3-4-17/h1-2,5-7,9H,3-4,8H2	PNPKQVICELDSLM-UHFFFAOYSA-N	396834	US9981950, Example 41	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26.2							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870156	405266902							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792990	CCc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C14H13ClFN5/c1-2-14-17-5-6-20(14)8-10-9-21(19-18-10)11-3-4-13(16)12(15)7-11/h3-7,9H,2,8H2,1H3	JFZBXZHTGAUVGD-UHFFFAOYSA-N	396835	US9981950, Example 42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5.02							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396835&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870081	405266903							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792991	CCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C15H15ClFN5/c1-2-3-15-18-6-7-21(15)9-11-10-22(20-19-11)12-4-5-14(17)13(16)8-12/h4-8,10H,2-3,9H2,1H3	WMFPPBDLJCGXMI-UHFFFAOYSA-N	396836	US9981950, Example 43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9.84							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396836&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870144	405266904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792992	Fc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13ClFN5/c16-13-7-12(3-4-14(13)17)22-9-11(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	LSZVDBKEFVBAEY-UHFFFAOYSA-N	396837	US9981950, Example 44	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 28.3							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396837&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870088	405266905							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792993	CCCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C16H17ClFN5/c1-2-3-4-16-19-7-8-22(16)10-12-11-23(21-20-12)13-5-6-15(18)14(17)9-13/h5-9,11H,2-4,10H2,1H3	VTFRNZQXDOHSFI-UHFFFAOYSA-N	396838	US9981950, Example 45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.68							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396838&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870176	405266906							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792994	Cc1nc(C)n(Cc2cn(nn2)-c2ccccc2)n1	InChI=1S/C13H14N6/c1-10-14-11(2)18(16-10)8-12-9-19(17-15-12)13-6-4-3-5-7-13/h3-7,9H,8H2,1-2H3	KTZHEMRJQDFTCV-UHFFFAOYSA-N	396839	US9981950, Example 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396839&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870172	405266907							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792995	Cc1nc(CO)n(Cc2cn(nn2)-c2ccccc2)n1	InChI=1S/C13H14N6O/c1-10-14-13(9-20)19(16-10)8-11-7-18(17-15-11)12-5-3-2-4-6-12/h2-7,20H,8-9H2,1H3	UXSIIBKTGUUEGS-UHFFFAOYSA-N	396840	US9981950, Example 47	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396840&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870073	405266908							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792996	Cc1nc(CO)nn1Cc1cn(nn1)-c1ccccc1	InChI=1S/C13H14N6O/c1-10-14-13(9-20)16-18(10)7-11-8-19(17-15-11)12-5-3-2-4-6-12/h2-6,8,20H,7,9H2,1H3	BJVGWMGSBBDWKY-UHFFFAOYSA-N	396841	US9981950, Example 48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396841&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870106	405266909							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792997	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1Cl	InChI=1S/C13H11Cl2N5/c1-9-16-4-5-19(9)7-11-8-20(18-17-11)13-3-2-10(14)6-12(13)15/h2-6,8H,7H2,1H3	VYRSMGXIQJIWHO-UHFFFAOYSA-N	396842	US9981950, Example 49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 778							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870173	405266910							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792998	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(F)c1	InChI=1S/C13H11ClFN5/c1-9-16-4-5-19(9)7-10-8-20(18-17-10)11-2-3-12(14)13(15)6-11/h2-6,8H,7H2,1H3	FMTUKULXLDFHHK-UHFFFAOYSA-N	396843	US9981950, Example 50	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21.2							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396843&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870117	405266911							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
792999	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C13H11ClFN5/c1-9-16-4-5-19(9)7-10-8-20(18-17-10)11-2-3-13(15)12(14)6-11/h2-6,8H,7H2,1H3	RIWYADOJEYZZRZ-UHFFFAOYSA-N	396844	US9981950, Example 51	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.01							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396844&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870180	405266912							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793000	COc1cc(F)ccc1-n1cc(Cn2ccnc2C)nn1	InChI=1S/C14H14FN5O/c1-10-16-5-6-19(10)8-12-9-20(18-17-12)13-4-3-11(15)7-14(13)21-2/h3-7,9H,8H2,1-2H3	VAYNXGJHBAWNOK-UHFFFAOYSA-N	396845	US9981950, Example 52	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1180							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396845&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870171	405266913							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793001	Cc1nccn1Cc1cn(nn1)-c1ccc(C)c(F)c1	InChI=1S/C14H14FN5/c1-10-3-4-13(7-14(10)15)20-9-12(17-18-20)8-19-6-5-16-11(19)2/h3-7,9H,8H2,1-2H3	VNHDHBHZGUTBRW-UHFFFAOYSA-N	396846	US9981950, Example 53	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26.5							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396846&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870125	405266914							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793002	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(C)c1	InChI=1S/C14H14FN5/c1-10-7-13(3-4-14(10)15)20-9-12(17-18-20)8-19-6-5-16-11(19)2/h3-7,9H,8H2,1-2H3	SUUBNQYDSCYRFB-UHFFFAOYSA-N	396847	US9981950, Example 54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5.32							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396847&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870127	405266915							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793003	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1	InChI=1S/C14H14ClN5/c1-10-7-13(3-4-14(10)15)20-9-12(17-18-20)8-19-6-5-16-11(19)2/h3-7,9H,8H2,1-2H3	UJRJRHMCPMPBNM-UHFFFAOYSA-N	396848	US9981950, Example 55	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.64							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396848&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870100	405266916							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793004	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)(F)F	InChI=1S/C14H11ClF3N5/c1-9-19-4-5-22(9)7-10-8-23(21-20-10)11-2-3-13(15)12(6-11)14(16,17)18/h2-6,8H,7H2,1H3	DRHMCKZRSIYNSH-UHFFFAOYSA-N	396849	US9981950, Example 56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11.9							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396849&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870142	405266917							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793005	Cc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C14H12F3N5O/c1-10-18-5-6-21(10)8-11-9-22(20-19-11)12-3-2-4-13(7-12)23-14(15,16)17/h2-7,9H,8H2,1H3	PSNQKKDWPZLWKY-UHFFFAOYSA-N	396850	US9981950, Example 57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.21							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396850&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870077	405266918							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793006	Cc1nccn1Cc1cn(nn1)-c1cccc(c1)C(F)(F)F	InChI=1S/C14H12F3N5/c1-10-18-5-6-21(10)8-12-9-22(20-19-12)13-4-2-3-11(7-13)14(15,16)17/h2-7,9H,8H2,1H3	VFTFBBYRZOXORC-UHFFFAOYSA-N	396851	US9981950, Example 58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17.4							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396851&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870061	405266919							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793007	Cc1nccn1Cc1cn(nn1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C14H12F3N5/c1-10-18-6-7-21(10)8-12-9-22(20-19-12)13-4-2-11(3-5-13)14(15,16)17/h2-7,9H,8H2,1H3	BLCNKRJMNGQWJU-UHFFFAOYSA-N	396852	US9981950, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46.0							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396852&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870137	405266920							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793008	Clc1ccc(c(Cl)c1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13Cl2N5/c16-11-3-4-14(13(17)7-11)22-9-12(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	RZJJYMUPIPAFHM-UHFFFAOYSA-N	396853	US9981950, Example 60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1620							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396853&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870113	405266921							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793009	Fc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13ClFN5/c16-13-4-3-12(7-14(13)17)22-9-11(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	BJBDOPNIPHEBTL-UHFFFAOYSA-N	396854	US9981950, Example 61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 31.7							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396854	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396854&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870181	405266922							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793010	COc1cc(F)ccc1-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16FN5O/c1-23-15-8-12(17)4-5-14(15)22-10-13(19-20-22)9-21-7-6-18-16(21)11-2-3-11/h4-8,10-11H,2-3,9H2,1H3	VYUWAHTYQGQTNF-UHFFFAOYSA-N	396855	US9981950, Example 62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3320							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396855	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396855&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870072	405266923							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793011	Cc1ccc(cc1F)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16FN5/c1-11-2-5-14(8-15(11)17)22-10-13(19-20-22)9-21-7-6-18-16(21)12-3-4-12/h2,5-8,10,12H,3-4,9H2,1H3	UZACFXZVMOVAMD-UHFFFAOYSA-N	396856	US9981950, Example 63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 87.1							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396856	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396856&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870169	405266924							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793012	Cc1cc(ccc1F)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16FN5/c1-11-8-14(4-5-15(11)17)22-10-13(19-20-22)9-21-7-6-18-16(21)12-2-3-12/h4-8,10,12H,2-3,9H2,1H3	BTLPJWLNOBZJLX-UHFFFAOYSA-N	396857	US9981950, Example 64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.1							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396857&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870104	405266925							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793013	Cc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16ClN5/c1-11-8-14(4-5-15(11)17)22-10-13(19-20-22)9-21-7-6-18-16(21)12-2-3-12/h4-8,10,12H,2-3,9H2,1H3	LCRLHAYDJUFDBS-UHFFFAOYSA-N	396858	US9981950, Example 65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12.4							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396858	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396858&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870096	405266926							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793014	FC(F)(F)c1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H13ClF3N5/c17-14-4-3-12(7-13(14)16(18,19)20)25-9-11(22-23-25)8-24-6-5-21-15(24)10-1-2-10/h3-7,9-10H,1-2,8H2	UULWSVSDBXUUNT-UHFFFAOYSA-N	396859	US9981950, Example 66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 38.0							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396859	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396859&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870120	405266927							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793015	FC(F)(F)Oc1cccc(c1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5O/c17-16(18,19)25-14-3-1-2-13(8-14)24-10-12(21-22-24)9-23-7-6-20-15(23)11-4-5-11/h1-3,6-8,10-11H,4-5,9H2	BINRGTLWUGYJBP-UHFFFAOYSA-N	396860	US9981950, Example 67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 34.5							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396860	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396860&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870183	405266928							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793016	FC(F)(F)c1cccc(c1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5/c17-16(18,19)12-2-1-3-14(8-12)24-10-13(21-22-24)9-23-7-6-20-15(23)11-4-5-11/h1-3,6-8,10-11H,4-5,9H2	IECCSHSCJSNUFX-UHFFFAOYSA-N	396861	US9981950, Example 68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 91.6							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396861	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396861&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870160	405266929							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793017	FC(F)(F)c1ccc(cc1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5/c17-16(18,19)12-3-5-14(6-4-12)24-10-13(21-22-24)9-23-8-7-20-15(23)11-1-2-11/h3-8,10-11H,1-2,9H2	NMIQLTRGPMQQII-UHFFFAOYSA-N	396862	US9981950, Example 69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 173							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396862	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396862&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870170	405266930							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793018	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1	InChI=1S/C15H16ClN5/c1-3-15-17-6-7-20(15)9-12-10-21(19-18-12)13-4-5-14(16)11(2)8-13/h4-8,10H,3,9H2,1-2H3	HQQFCWPHPRSGTH-UHFFFAOYSA-N	396863	US9981950, Example 70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.84							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396863&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870071	405266931							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793019	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1	InChI=1S/C16H18ClN5/c1-11(2)16-18-6-7-21(16)9-13-10-22(20-19-13)14-4-5-15(17)12(3)8-14/h4-8,10-11H,9H2,1-3H3	PNOCWPPPUIQTEQ-UHFFFAOYSA-N	396864	US9981950, Example 71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.47							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396864	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396864&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870153	405266932							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793020	CCc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C15H14F3N5O/c1-2-14-19-6-7-22(14)9-11-10-23(21-20-11)12-4-3-5-13(8-12)24-15(16,17)18/h3-8,10H,2,9H2,1H3	ZUBNWKBIEHKLQD-UHFFFAOYSA-N	396865	US9981950, Example 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11.4							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396865	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396865&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870182	405266933							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793021	CC(C)c1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C16H16F3N5O/c1-11(2)15-20-6-7-23(15)9-12-10-24(22-21-12)13-4-3-5-14(8-13)25-16(17,18)19/h3-8,10-11H,9H2,1-2H3	DZEGAUUMJVVSNN-UHFFFAOYSA-N	396866	US9981950, Example 73	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32.7							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396866&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870098	405266934							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793022	Cc1cc(ccc1Cl)-n1cc(Cn2ccnc2CCO)nn1	InChI=1S/C15H16ClN5O/c1-11-8-13(2-3-14(11)16)21-10-12(18-19-21)9-20-6-5-17-15(20)4-7-22/h2-3,5-6,8,10,22H,4,7,9H2,1H3	QGHUYWCWQWJAPH-UHFFFAOYSA-N	396867	US9981950, Example 74	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6.90							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396867&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870115	405266935							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793023	Cc1cc(ccc1Cl)-n1cc(Cn2ccnc2CCF)nn1	InChI=1S/C15H15ClFN5/c1-11-8-13(2-3-14(11)16)22-10-12(19-20-22)9-21-7-6-18-15(21)4-5-17/h2-3,6-8,10H,4-5,9H2,1H3	KOJCWZJFTKOHIH-UHFFFAOYSA-N	396868	US9981950, Example 75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13.5							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396868&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870086	405266936							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793024	Cc1nccn1Cc1cn(nn1)-c1cccc(c1)C1CC1	InChI=1S/C16H17N5/c1-12-17-7-8-20(12)10-15-11-21(19-18-15)16-4-2-3-14(9-16)13-5-6-13/h2-4,7-9,11,13H,5-6,10H2,1H3	BCMMYCCUZMUCKE-UHFFFAOYSA-N	396869	US9981950, Example 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.9							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396869&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870159	405266937							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793025	Cc1nccn1Cc1cn(nn1)-c1cccc(c1)S(C)(=O)=O	InChI=1S/C14H15N5O2S/c1-11-15-6-7-18(11)9-12-10-19(17-16-12)13-4-3-5-14(8-13)22(2,20)21/h3-8,10H,9H2,1-2H3	FTODECXLANNKPC-UHFFFAOYSA-N	396870	US9981950, Example 77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 615							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396870&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870110	405266938							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793026	OCCc1nccn1Cc1cn(nn1)-c1cccc(c1)C1CC1	InChI=1S/C17H19N5O/c23-9-6-17-18-7-8-21(17)11-15-12-22(20-19-15)16-3-1-2-14(10-16)13-4-5-13/h1-3,7-8,10,12-13,23H,4-6,9,11H2	QUXRRGHMYGOPOY-UHFFFAOYSA-N	396871	US9981950, Example 78	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 41.1							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396871	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870059	405266939							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793027	CS(=O)(=O)c1cccc(c1)-n1cc(Cn2ccnc2CCO)nn1	InChI=1S/C15H17N5O3S/c1-24(22,23)14-4-2-3-13(9-14)20-11-12(17-18-20)10-19-7-6-16-15(19)5-8-21/h2-4,6-7,9,11,21H,5,8,10H2,1H3	JOCVQBDURVHERC-UHFFFAOYSA-N	396872	US9981950, Example 79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1400							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396872&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870121	405266940							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793028	CS(=O)(=O)c1cccc(c1)-n1cc(Cn2ccnc2CCF)nn1	InChI=1S/C15H16FN5O2S/c1-24(22,23)14-4-2-3-13(9-14)21-11-12(18-19-21)10-20-8-7-17-15(20)5-6-16/h2-4,7-9,11H,5-6,10H2,1H3	KLOSGRVATVPBIQ-UHFFFAOYSA-N	396873	US9981950, Example 80	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2680							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870126	405266941							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793029	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C14H12F3N5/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-13(15)12(6-11)14(16)17/h2-6,8,14H,7H2,1H3	QSKZBFJMOFMZSF-UHFFFAOYSA-N	396874	US9981950, Example 81	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.83							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396874&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870064	405266942							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793030	FC(F)c1cc(ccc1F)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5/c17-14-4-3-12(7-13(14)15(18)19)24-9-11(21-22-24)8-23-6-5-20-16(23)10-1-2-10/h3-7,9-10,15H,1-2,8H2	XRNXEVVICQRAAE-UHFFFAOYSA-N	396875	US9981950, Example 82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16.2							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396875&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870105	405266943							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793031	CCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C15H14F3N5/c1-2-14-19-5-6-22(14)8-10-9-23(21-20-10)11-3-4-13(16)12(7-11)15(17)18/h3-7,9,15H,2,8H2,1H3	PKKCOOQFVZMCHD-UHFFFAOYSA-N	396876	US9981950, Example 83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.11							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870146	405266944							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793032	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H16F3N5/c1-10(2)16-20-5-6-23(16)8-11-9-24(22-21-11)12-3-4-14(17)13(7-12)15(18)19/h3-7,9-10,15H,8H2,1-2H3	RHCWEINUWQCGDI-UHFFFAOYSA-N	396877	US9981950, Example 84	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11.0							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396877&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870079	405266945							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793033	CCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H16F3N5/c1-2-3-15-20-6-7-23(15)9-11-10-24(22-21-11)12-4-5-14(17)13(8-12)16(18)19/h4-8,10,16H,2-3,9H2,1H3	APCKLHZSVVXCSJ-UHFFFAOYSA-N	396878	US9981950, Example 85	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.40							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396878&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870139	405266946							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793034	CCCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C17H18F3N5/c1-2-3-4-16-21-7-8-24(16)10-12-11-25(23-22-12)13-5-6-15(18)14(9-13)17(19)20/h5-9,11,17H,2-4,10H2,1H3	ILHXDJNKXGVDCA-UHFFFAOYSA-N	396879	US9981950, Example 86	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.29							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396879	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396879&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870123	405266947							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793035	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C17H18F3N5/c1-17(2,3)16-21-6-7-24(16)9-11-10-25(23-22-11)12-4-5-14(18)13(8-12)15(19)20/h4-8,10,15H,9H2,1-3H3	PVCPERVVEUJKJP-UHFFFAOYSA-N	396880	US9981950, Example 87	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 131							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396880	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396880&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870099	405266948							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793036	OCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C15H14F3N5O/c16-13-2-1-11(7-12(13)15(17)18)23-9-10(20-21-23)8-22-5-4-19-14(22)3-6-24/h1-2,4-5,7,9,15,24H,3,6,8H2	WAGGNWZFAHXBMP-UHFFFAOYSA-N	396881	US9981950, Example 88	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 14.5							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396881	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396881&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870161	405266949							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793037	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C14H12ClF2N5/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-13(15)12(6-11)14(16)17/h2-6,8,14H,7H2,1H3	QLHBDCCSPGVPTO-UHFFFAOYSA-N	396882	US9981950, Example 89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.37							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396882&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870135	405266950							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793038	FC(F)c1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14ClF2N5/c17-14-4-3-12(7-13(14)15(18)19)24-9-11(21-22-24)8-23-6-5-20-16(23)10-1-2-10/h3-7,9-10,15H,1-2,8H2	JLSQSDCBSROECG-UHFFFAOYSA-N	396883	US9981950, Example 90	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.4							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396883	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396883&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870075	405266951							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793039	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C15H14ClF2N5/c1-2-14-19-5-6-22(14)8-10-9-23(21-20-10)11-3-4-13(16)12(7-11)15(17)18/h3-7,9,15H,2,8H2,1H3	CIAAWOPCBYSYLC-UHFFFAOYSA-N	396884	US9981950, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2.43							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396884	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396884&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870069	405266952							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793040	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C16H16ClF2N5/c1-10(2)16-20-5-6-23(16)8-11-9-24(22-21-11)12-3-4-14(17)13(7-12)15(18)19/h3-7,9-10,15H,8H2,1-2H3	PEDNWEQKMIWGBJ-UHFFFAOYSA-N	396885	US9981950, Example 92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5.24							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396885&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870070	405266953							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793041	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C14H12ClF2N5O/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-12(15)13(6-11)23-14(16)17/h2-6,8,14H,7H2,1H3	NTXPVEQQFPXEPU-UHFFFAOYSA-N	396886	US9981950, Example 93	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.20							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396886	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396886&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870103	405266954							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793042	FC(F)Oc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14ClF2N5O/c17-13-4-3-12(7-14(13)25-16(18)19)24-9-11(21-22-24)8-23-6-5-20-15(23)10-1-2-10/h3-7,9-10,16H,1-2,8H2	BHASKRVNSLNZGW-UHFFFAOYSA-N	396887	US9981950, Example 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.91							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396887	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396887&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870162	405266955							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793043	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C17H18ClF2N5O/c1-17(2,3)15-21-6-7-24(15)9-11-10-25(23-22-11)12-4-5-13(18)14(8-12)26-16(19)20/h4-8,10,16H,9H2,1-3H3	NXVWMYHMJCGROD-UHFFFAOYSA-N	396888	US9981950, Example 95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 72.9							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396888	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396888&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870141	405266956							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793044	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H14ClF2N5O/c1-2-14-19-5-6-22(14)8-10-9-23(21-20-10)11-3-4-12(16)13(7-11)24-15(17)18/h3-7,9,15H,2,8H2,1H3	RPRRSXXASCSWCX-UHFFFAOYSA-N	396889	US9981950, Example 96	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.60							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396889&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870179	405266957							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793045	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H16ClF2N5O/c1-10(2)15-20-5-6-23(15)8-11-9-24(22-21-11)12-3-4-13(17)14(7-12)25-16(18)19/h3-7,9-10,16H,8H2,1-2H3	OSODAZMEELVOGC-UHFFFAOYSA-N	396890	US9981950, Example 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.12							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396890	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396890&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870093	405266958							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793046	OCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H14ClF2N5O2/c16-12-2-1-11(7-13(12)25-15(17)18)23-9-10(20-21-23)8-22-5-4-19-14(22)3-6-24/h1-2,4-5,7,9,15,24H,3,6,8H2	SDYVDXMMCZXDQX-UHFFFAOYSA-N	396891	US9981950, Example 98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2.26							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396891	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396891&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870067	405266959							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793047	FCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H13ClF3N5O/c16-12-2-1-11(7-13(12)25-15(18)19)24-9-10(21-22-24)8-23-6-5-20-14(23)3-4-17/h1-2,5-7,9,15H,3-4,8H2	QFNOXQXTBCOOIT-UHFFFAOYSA-N	396892	US9981950, Example 99	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6.02							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396892	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396892&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870165	405266960							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793048	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C14H12F3N5O/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-12(15)13(6-11)23-14(16)17/h2-6,8,14H,7H2,1H3	OBJSITFIPOKILU-UHFFFAOYSA-N	396893	US9981950, Example 100	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.90							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396893	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396893&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870087	405266961							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793049	OCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C15H14F3N5O2/c16-12-2-1-11(7-13(12)25-15(17)18)23-9-10(20-21-23)8-22-5-4-19-14(22)3-6-24/h1-2,4-5,7,9,15,24H,3,6,8H2	CQYRYSJJBAIWRQ-UHFFFAOYSA-N	396894	US9981950, Example 101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.26							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396894	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396894&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870066	405266962							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793050	Cc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C14H12F3N5/c1-9-18-2-3-21(9)7-12-8-22(20-19-12)13-5-10(14(16)17)4-11(15)6-13/h2-6,8,14H,7H2,1H3	OCGOMHKIACWSMG-UHFFFAOYSA-N	396895	US9981950, Example 102	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25.9							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396895	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396895&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870138	405266963							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793051	OCCc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C15H14F3N5O/c16-11-5-10(15(17)18)6-13(7-11)23-9-12(20-21-23)8-22-3-2-19-14(22)1-4-24/h2-3,5-7,9,15,24H,1,4,8H2	XEAHOSRXLJEYBK-UHFFFAOYSA-N	396896	US9981950, Example 103	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 136							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396896	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396896&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870136	405266964							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793052	FCCc1nccn1Cc1cn(cn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C16H14F4N4/c17-2-1-15-21-3-4-23(15)8-13-9-24(10-22-13)14-6-11(16(19)20)5-12(18)7-14/h3-7,9-10,16H,1-2,8H2	VVIKQWDMFZZASA-UHFFFAOYSA-N	396897	US9981950, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 186							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396897	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396897&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			130310805	405266965							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793053	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C15H14F3N5/c1-10-19-5-6-22(10)8-11-9-23(21-20-11)12-3-4-14(16)13(7-12)15(2,17)18/h3-7,9H,8H2,1-2H3	UJPVZTKYGGHGLB-UHFFFAOYSA-N	396898	US9981950, Example 105	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.05							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396898&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870130	405266966							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793054	CC(F)(F)c1cc(ccc1F)-n1cc(Cn2ccnc2CCO)nn1	InChI=1S/C16H16F3N5O/c1-16(18,19)13-8-12(2-3-14(13)17)24-10-11(21-22-24)9-23-6-5-20-15(23)4-7-25/h2-3,5-6,8,10,25H,4,7,9H2,1H3	QULVTNJBHGMPJK-UHFFFAOYSA-N	396899	US9981950, Example 106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8.08							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396899&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870134	405266967							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793055	Cn1nccc1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C13H11ClFN5/c1-19-10(4-5-16-19)6-9-8-20(18-17-9)11-2-3-13(15)12(14)7-11/h2-5,7-8H,6H2,1H3	OMQQLDITRYIEHZ-UHFFFAOYSA-N	396900	US9981950, Example 109	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4320							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396900&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870060	405266968							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793056	Nc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C13H11ClF2N6O/c14-10-2-1-9(5-11(10)23-12(15)16)22-7-8(19-20-22)6-21-4-3-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	BRINTJVXMVTOJY-UHFFFAOYSA-N	396901	US9981950, Example 110	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.520							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396901&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870090	405266969							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793057	Nc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C13H11F3N6/c14-9-3-8(12(15)16)4-11(5-9)22-7-10(19-20-22)6-21-2-1-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	XNKTWVPPPLRTKJ-UHFFFAOYSA-N	396902	US9981950, Example 111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2.13							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396902&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870092	405266970							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793058	Nc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C13H11ClF2N6/c14-11-2-1-9(5-10(11)12(15)16)22-7-8(19-20-22)6-21-4-3-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	ZCROGTMUHYRBRR-UHFFFAOYSA-N	396903	US9981950, Example 113A	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.650							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396903&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870116	405266971							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793059	Nc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C13H11F3N6/c14-11-2-1-9(5-10(11)12(15)16)22-7-8(19-20-22)6-21-4-3-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	UZRIQFGTVHJEPZ-UHFFFAOYSA-N	396904	US9981950, Example 113B	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.480							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396904	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396904&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870083	405266972							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793060	CC(F)(F)c1cc(ccc1F)-n1cc(Cn2ccnc2N)nn1	InChI=1S/C14H13F3N6/c1-14(16,17)11-6-10(2-3-12(11)15)23-8-9(20-21-23)7-22-5-4-19-13(22)18/h2-6,8H,7H2,1H3,(H2,18,19)	WKSZMTYLSCHZID-UHFFFAOYSA-N	396905	US9981950, Example 114	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.510							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396905	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396905&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870107	405266973							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793061	FC(F)c1cc(ccc1F)-n1cc(Cc2cc[nH]n2)nn1	InChI=1S/C13H10F3N5/c14-12-2-1-10(6-11(12)13(15)16)21-7-9(19-20-21)5-8-3-4-17-18-8/h1-4,6-7,13H,5H2,(H,17,18)	XCUYCJFGWDLGRI-UHFFFAOYSA-N	396906	US9981950, Example 115	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 236							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870128	405266974							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793062	Cc1ccc(cc1)C(=O)c1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C20H16ClN5O/c1-14-2-4-15(5-3-14)19(27)20-22-10-11-25(20)12-17-13-26(24-23-17)18-8-6-16(21)7-9-18/h2-11,13H,12H2,1H3	FMXPLHPTIXIQOD-UHFFFAOYSA-N	396907	US9981950, Example 116	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>5000							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396907	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396907&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870082	405266975							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793063	Cc1nc2ccccc2n1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C17H13Cl2N5/c1-11-20-16-4-2-3-5-17(16)23(11)9-12-10-24(22-21-12)13-6-7-14(18)15(19)8-13/h2-8,10H,9H2,1H3	NBDNSJRTVZQEOU-UHFFFAOYSA-N	396908	US9981950, Example 117	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 141							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396908&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870085	405266976							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
793064	OCCc1nccn1Cn1cc(nn1)-c1ccc(cc1)S(F)(F)(F)(F)F	InChI=1S/C14H14F5N5OS/c15-26(16,17,18,19)12-3-1-11(2-4-12)13-9-24(22-21-13)10-23-7-6-20-14(23)5-8-25/h1-4,6-7,9,25H,5,8,10H2	PTIUBUNBWISPMY-UHFFFAOYSA-N	396909	US9981950, Example 118	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 263							US Patent		10.7270/Q2TH8Q1D		aid1799103	US9981950	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	5/29/2018	4/18/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396909	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396909&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			130310806	405266977							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796351	Cc1nc(C)n(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C13H13ClN6/c1-9-15-10(2)19(17-9)7-12-8-20(18-16-12)13-5-3-11(14)4-6-13/h3-6,8H,7H2,1-2H3	AQLRWJVRJUSCJS-UHFFFAOYSA-N	396794	US9981950, Example 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396794	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396794&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71970823	405266862							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796352	CCCc1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C14H15ClN6/c1-2-3-14-16-10-17-21(14)9-12-8-20(19-18-12)13-6-4-11(15)5-7-13/h4-8,10H,2-3,9H2,1H3	IWNKFQATMQELSV-UHFFFAOYSA-N	396795	US9981950, Example 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396795	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396795&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870145	405266863							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796353	CCCc1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C14H15ClN6/c1-2-3-14-16-10-20(18-14)8-12-9-21(19-17-12)13-6-4-11(15)5-7-13/h4-7,9-10H,2-3,8H2,1H3	RZCIDOWEQOSVFU-UHFFFAOYSA-N	396796	US9981950, Example 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396796	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396796&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870129	405266864							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796354	CC(C)c1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C14H15ClN6/c1-10(2)14-16-9-20(18-14)7-12-8-21(19-17-12)13-5-3-11(15)4-6-13/h3-6,8-10H,7H2,1-2H3	PWVKLWNAGDSQLN-UHFFFAOYSA-N	396797	US9981950, Example 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396797	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396797&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870132	405266865							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796355	CCc1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C13H13ClN6/c1-2-13-15-9-16-20(13)8-11-7-19(18-17-11)12-5-3-10(14)4-6-12/h3-7,9H,2,8H2,1H3	VKYQAXYBRHJTAL-UHFFFAOYSA-N	396798	US9981950, Example 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396798	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396798&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870177	405266866							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796356	CCc1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C13H13ClN6/c1-2-13-15-9-19(17-13)7-11-8-20(18-16-11)12-5-3-10(14)4-6-12/h3-6,8-9H,2,7H2,1H3	HRQZQCFVMLFYSB-UHFFFAOYSA-N	396799	US9981950, Example 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396799	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396799&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870068	405266867							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796357	CC(C)c1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C14H15ClN6/c1-10(2)14-16-9-17-21(14)8-12-7-20(19-18-12)13-5-3-11(15)4-6-13/h3-7,9-10H,8H2,1-2H3	DSHSWXIKZMKFMX-UHFFFAOYSA-N	396800	US9981950, Example 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396800	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396800&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870062	405266868							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796358	Cc1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H11ClN6/c1-9-14-8-15-18(9)6-11-7-19(17-16-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	AMYCLBLRVRIJGO-UHFFFAOYSA-N	396801	US9981950, Example 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 14300							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396801	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396801&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870157	405266869							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796359	Cc1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C12H11ClN6/c1-9-14-8-18(16-9)6-11-7-19(17-15-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	TXAHJZVCNFFEJR-UHFFFAOYSA-N	396802	US9981950, Example 9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396802	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396802&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870118	405266870							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796360	Clc1ccc(cc1)-n1cc(Cn2nc(nc2C2CC2)C2CC2)nn1	InChI=1S/C17H17ClN6/c18-13-5-7-15(8-6-13)23-9-14(20-22-23)10-24-17(12-3-4-12)19-16(21-24)11-1-2-11/h5-9,11-12H,1-4,10H2	LVBHPJLNQRYDTB-UHFFFAOYSA-N	396803	US9981950, Example 10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396803	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396803&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870111	405266871							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796361	Clc1ccc(cc1)-n1cc(Cn2ncnc2C2CCC2)nn1	InChI=1S/C15H15ClN6/c16-12-4-6-14(7-5-12)21-8-13(19-20-21)9-22-15(17-10-18-22)11-2-1-3-11/h4-8,10-11H,1-3,9H2	QKBPERVPIARHRO-UHFFFAOYSA-N	396804	US9981950, Example 11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>1000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396804	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396804&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870078	405266872							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796362	Clc1ccc(cc1)-n1cc(Cn2cnc(n2)C2CCC2)nn1	InChI=1S/C15H15ClN6/c16-12-4-6-14(7-5-12)22-9-13(18-20-22)8-21-10-17-15(19-21)11-2-1-3-11/h4-7,9-11H,1-3,8H2	CWHJIHOWGGKGEA-UHFFFAOYSA-N	396805	US9981950, Example 12	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396805	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396805&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870140	405266873							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796363	Clc1ccc(cc1)-n1cc(Cn2cnc(n2)C2CC2)nn1	InChI=1S/C14H13ClN6/c15-11-3-5-13(6-4-11)21-8-12(17-19-21)7-20-9-16-14(18-20)10-1-2-10/h3-6,8-10H,1-2,7H2	FYLLXYYSVQPAKZ-UHFFFAOYSA-N	396806	US9981950, Example 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396806	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396806&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870149	405266874							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796364	Clc1ccc(cc1)-n1cc(Cn2ncnc2C2CCCC2)nn1	InChI=1S/C16H17ClN6/c17-13-5-7-15(8-6-13)22-9-14(20-21-22)10-23-16(18-11-19-23)12-3-1-2-4-12/h5-9,11-12H,1-4,10H2	FDBRNTUVWGVIAY-UHFFFAOYSA-N	396807	US9981950, Example 14	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12500							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396807	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396807&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870152	405266875							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796365	Clc1ccc(cc1)-n1cc(Cn2cnc(n2)C2CCCC2)nn1	InChI=1S/C16H17ClN6/c17-13-5-7-15(8-6-13)23-10-14(19-21-23)9-22-11-18-16(20-22)12-3-1-2-4-12/h5-8,10-12H,1-4,9H2	AQRMSNKJMMOWNY-UHFFFAOYSA-N	396808	US9981950, Example 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396808	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396808&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870148	405266876							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796366	Clc1ccc(cc1)-n1cc(Cn2ncnc2C2CC2)nn1	InChI=1S/C14H13ClN6/c15-11-3-5-13(6-4-11)20-7-12(18-19-20)8-21-14(10-1-2-10)16-9-17-21/h3-7,9-10H,1-2,8H2	OETSVHHBHCIQTP-UHFFFAOYSA-N	396809	US9981950, Example 16	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396809	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396809&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870124	405266877							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796367	FC(F)(F)c1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C12H8ClF3N6/c13-8-1-3-10(4-2-8)22-6-9(18-20-22)5-21-7-17-11(19-21)12(14,15)16/h1-4,6-7H,5H2	CAIRHTFTLPIFQU-UHFFFAOYSA-N	396810	US9981950, Example 17	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396810	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396810&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870076	405266878							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796368	CCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C15H16ClN5/c1-2-3-15-17-8-9-20(15)10-13-11-21(19-18-13)14-6-4-12(16)5-7-14/h4-9,11H,2-3,10H2,1H3	AYJDATHUPMMOSP-UHFFFAOYSA-N	396811	US9981950, Example 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46.6							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396811	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396811&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870063	405266879							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796369	CC(C)(C)c1ncnn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C15H17ClN6/c1-15(2,3)14-17-10-18-22(14)9-12-8-21(20-19-12)13-6-4-11(16)5-7-13/h4-8,10H,9H2,1-3H3	NNARYJXWYNWMSY-UHFFFAOYSA-N	396812	US9981950, Example 19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396812	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396812&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870133	405266880							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796370	CC(C)(C)c1ncn(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C15H17ClN6/c1-15(2,3)14-17-10-21(19-14)8-12-9-22(20-18-12)13-6-4-11(16)5-7-13/h4-7,9-10H,8H2,1-3H3	WTTBNWBKWZDRPV-UHFFFAOYSA-N	396813	US9981950, Example 20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396813	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396813&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870151	405266881							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796371	Cc1nc(C2CCC2)n(Cc2cn(nn2)-c2ccc(Cl)cc2)n1	InChI=1S/C16H17ClN6/c1-11-18-16(12-3-2-4-12)23(20-11)10-14-9-22(21-19-14)15-7-5-13(17)6-8-15/h5-9,12H,2-4,10H2,1H3	KTERBHGAOPMQME-UHFFFAOYSA-N	396814	US9981950, Example 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396814	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396814&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870178	405266882							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796372	Cc1nc(nn1Cc1cn(nn1)-c1ccc(Cl)cc1)C1CCC1	InChI=1S/C16H17ClN6/c1-11-18-16(12-3-2-4-12)20-22(11)9-14-10-23(21-19-14)15-7-5-13(17)6-8-15/h5-8,10,12H,2-4,9H2,1H3	BGVIDOSBQYMVSL-UHFFFAOYSA-N	396815	US9981950, Example 22	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396815	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396815&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870154	405266883							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796373	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C15H16ClN5/c1-11(2)15-17-7-8-20(15)9-13-10-21(19-18-13)14-5-3-12(16)4-6-14/h3-8,10-11H,9H2,1-2H3	NRWRQBPXPZXDGL-UHFFFAOYSA-N	396816	US9981950, Example 23	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 77.4							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396816	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396816&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870080	405266884							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796374	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C13H12ClN5/c1-10-15-6-7-18(10)8-12-9-19(17-16-12)13-4-2-11(14)3-5-13/h2-7,9H,8H2,1H3	OCWFBNMIXTWOIS-UHFFFAOYSA-N	396817	US9981950, Example 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 38.4							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396817	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396817&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870164	405266885							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796375	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C14H14ClN5/c1-2-14-16-7-8-19(14)9-12-10-20(18-17-12)13-5-3-11(15)4-6-13/h3-8,10H,2,9H2,1H3	UHCWOUZOICIRGT-UHFFFAOYSA-N	396818	US9981950, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25.8							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396818	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396818&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870095	405266886							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796376	Clc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H9Cl2N5/c13-9-1-3-11(4-2-9)19-8-10(16-17-19)7-18-6-5-15-12(18)14/h1-6,8H,7H2	IVDHBJSENGBWTH-UHFFFAOYSA-N	396819	US9981950, Example 26	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9930							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396819	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396819&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870174	405266887							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796377	CCCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C16H18ClN5/c1-2-3-4-16-18-9-10-21(16)11-14-12-22(20-19-14)15-7-5-13(17)6-8-15/h5-10,12H,2-4,11H2,1H3	CEAOOXKEMXDLAB-UHFFFAOYSA-N	396820	US9981950, Example 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 38.9							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396820	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396820&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870108	405266888							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796378	OCc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C13H12ClN5O/c14-10-1-3-12(4-2-10)19-8-11(16-17-19)7-18-6-5-15-13(18)9-20/h1-6,8,20H,7,9H2	MVPGLWBEKNSVHN-UHFFFAOYSA-N	396821	US9981950, Example 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 573							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396821	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396821&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870158	405266889							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796379	Clc1ccc(cc1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H14ClN5/c16-12-3-5-14(6-4-12)21-10-13(18-19-21)9-20-8-7-17-15(20)11-1-2-11/h3-8,10-11H,1-2,9H2	UCXUHYULIWVCHH-UHFFFAOYSA-N	396822	US9981950, Example 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 95.8							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396822	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396822&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870091	405266890							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796380	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C16H18ClN5/c1-16(2,3)15-18-8-9-21(15)10-13-11-22(20-19-13)14-6-4-12(17)5-7-14/h4-9,11H,10H2,1-3H3	KHTCVPAURHYMJW-UHFFFAOYSA-N	396823	US9981950, Example 30::2-tert-butyl-1H- imidazole 4-(2-tert-Butyl-imidazol-1-ylmethyl)-1-(4-chloro- phenyl)-1H-[1,2,3]triazole	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7200							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396823&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870163	405266891							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796381	Cc1nncn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H11ClN6/c1-9-15-14-8-18(9)6-11-7-19(17-16-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	LMZPNUTXBLCHOF-UHFFFAOYSA-N	396824	US9981950, Example 31::2-methyl-1H- imidazole 1-(4-Chloro-phenyl)-4-(3-methyl-[1,2,4]triazol-4- ylmethyl)-1H-[1,2,3]triazole	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870102	405266892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796382	Cc1nncn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C12H11ClN6/c1-9-15-14-8-18(9)6-11-7-19(17-16-11)12-4-2-10(13)3-5-12/h2-5,7-8H,6H2,1H3	LMZPNUTXBLCHOF-UHFFFAOYSA-N	396824	US9981950, Example 31::2-methyl-1H- imidazole 1-(4-Chloro-phenyl)-4-(3-methyl-[1,2,4]triazol-4- ylmethyl)-1H-[1,2,3]triazole	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.92							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396824	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396824&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870102	405266892							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796383	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C14H13Cl2N5/c1-2-14-17-5-6-20(14)8-10-9-21(19-18-10)11-3-4-12(15)13(16)7-11/h3-7,9H,2,8H2,1H3	ACNAPZHYUZOZJN-UHFFFAOYSA-N	396826	US9981950, Example 33	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.65							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396826&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870147	405266894							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796384	CCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C15H15Cl2N5/c1-2-3-15-18-6-7-21(15)9-11-10-22(20-19-11)12-4-5-13(16)14(17)8-12/h4-8,10H,2-3,9H2,1H3	VBCLULJZISPDRO-UHFFFAOYSA-N	396827	US9981950, Example 34	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.67							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396827&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870114	405266895							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796385	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C15H15Cl2N5/c1-10(2)15-18-5-6-21(15)8-11-9-22(20-19-11)12-3-4-13(16)14(17)7-12/h3-7,9-10H,8H2,1-2H3	AJGOWAAIQPCIPM-UHFFFAOYSA-N	396828	US9981950, Example 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.40							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870155	405266896							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796386	Clc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13Cl2N5/c16-13-4-3-12(7-14(13)17)22-9-11(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	IEGRHOUALWXAMI-UHFFFAOYSA-N	396829	US9981950, Example 36	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17.9							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396829&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870167	405266897							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796387	CCCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C16H17Cl2N5/c1-2-3-4-16-19-7-8-22(16)10-12-11-23(21-20-12)13-5-6-14(17)15(18)9-13/h5-9,11H,2-4,10H2,1H3	FABOZFZSWJBLAK-UHFFFAOYSA-N	396830	US9981950, Example 37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6.84							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396830&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870184	405266898							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796388	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C16H17Cl2N5/c1-16(2,3)15-19-6-7-22(15)9-11-10-23(21-20-11)12-4-5-13(17)14(18)8-12/h4-8,10H,9H2,1-3H3	ABOXKYVSSWHNON-UHFFFAOYSA-N	396831	US9981950, Example 38	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 526							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396831	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396831&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870101	405266899							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796389	Clc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CCC2)nn1	InChI=1S/C16H15Cl2N5/c17-14-5-4-13(8-15(14)18)23-10-12(20-21-23)9-22-7-6-19-16(22)11-2-1-3-11/h4-8,10-11H,1-3,9H2	YUDVHEROTXDJBH-UHFFFAOYSA-N	396832	US9981950, Example 39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.58							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396832	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396832&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870109	405266900							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796390	OCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C14H13Cl2N5O/c15-12-2-1-11(7-13(12)16)21-9-10(18-19-21)8-20-5-4-17-14(20)3-6-22/h1-2,4-5,7,9,22H,3,6,8H2	HRJGAGOKRFPCOH-UHFFFAOYSA-N	396833	US9981950, Example 40	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17.2							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396833	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396833&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870119	405266901							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796391	FCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C14H12Cl2FN5/c15-12-2-1-11(7-13(12)16)22-9-10(19-20-22)8-21-6-5-18-14(21)3-4-17/h1-2,5-7,9H,3-4,8H2	PNPKQVICELDSLM-UHFFFAOYSA-N	396834	US9981950, Example 41	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26.2							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396834	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396834&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870156	405266902							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796392	CCc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C14H13ClFN5/c1-2-14-17-5-6-20(14)8-10-9-21(19-18-10)11-3-4-13(16)12(15)7-11/h3-7,9H,2,8H2,1H3	JFZBXZHTGAUVGD-UHFFFAOYSA-N	396835	US9981950, Example 42	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5.02							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396835	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396835&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870081	405266903							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796393	CCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C15H15ClFN5/c1-2-3-15-18-6-7-21(15)9-11-10-22(20-19-11)12-4-5-14(17)13(16)8-12/h4-8,10H,2-3,9H2,1H3	WMFPPBDLJCGXMI-UHFFFAOYSA-N	396836	US9981950, Example 43	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9.84							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396836	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396836&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870144	405266904							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796394	Fc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13ClFN5/c16-13-7-12(3-4-14(13)17)22-9-11(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	LSZVDBKEFVBAEY-UHFFFAOYSA-N	396837	US9981950, Example 44	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 28.3							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396837	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396837&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870088	405266905							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796395	CCCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C16H17ClFN5/c1-2-3-4-16-19-7-8-22(16)10-12-11-23(21-20-12)13-5-6-15(18)14(17)9-13/h5-9,11H,2-4,10H2,1H3	VTFRNZQXDOHSFI-UHFFFAOYSA-N	396838	US9981950, Example 45	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.68							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396838	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396838&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870176	405266906							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796396	Cc1nc(C)n(Cc2cn(nn2)-c2ccccc2)n1	InChI=1S/C13H14N6/c1-10-14-11(2)18(16-10)8-12-9-19(17-15-12)13-6-4-3-5-7-13/h3-7,9H,8H2,1-2H3	KTZHEMRJQDFTCV-UHFFFAOYSA-N	396839	US9981950, Example 46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396839	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396839&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870172	405266907							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796397	Cc1nc(CO)n(Cc2cn(nn2)-c2ccccc2)n1	InChI=1S/C13H14N6O/c1-10-14-13(9-20)19(16-10)8-11-7-18(17-15-11)12-5-3-2-4-6-12/h2-7,20H,8-9H2,1H3	UXSIIBKTGUUEGS-UHFFFAOYSA-N	396840	US9981950, Example 47	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396840	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396840&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870073	405266908							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796398	Cc1nc(CO)nn1Cc1cn(nn1)-c1ccccc1	InChI=1S/C13H14N6O/c1-10-14-13(9-20)16-18(10)7-11-8-19(17-15-11)12-5-3-2-4-6-12/h2-6,8,20H,7,9H2,1H3	BJVGWMGSBBDWKY-UHFFFAOYSA-N	396841	US9981950, Example 48	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396841	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396841&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870106	405266909							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796399	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1Cl	InChI=1S/C13H11Cl2N5/c1-9-16-4-5-19(9)7-11-8-20(18-17-11)13-3-2-10(14)6-12(13)15/h2-6,8H,7H2,1H3	VYRSMGXIQJIWHO-UHFFFAOYSA-N	396842	US9981950, Example 49	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 778							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396842	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396842&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870173	405266910							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796400	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(F)c1	InChI=1S/C13H11ClFN5/c1-9-16-4-5-19(9)7-10-8-20(18-17-10)11-2-3-12(14)13(15)6-11/h2-6,8H,7H2,1H3	FMTUKULXLDFHHK-UHFFFAOYSA-N	396843	US9981950, Example 50	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 21.2							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396843	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396843&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870117	405266911							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796401	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C13H11ClFN5/c1-9-16-4-5-19(9)7-10-8-20(18-17-10)11-2-3-13(15)12(14)6-11/h2-6,8H,7H2,1H3	RIWYADOJEYZZRZ-UHFFFAOYSA-N	396844	US9981950, Example 51	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.01							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396844	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396844&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870180	405266912							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796402	COc1cc(F)ccc1-n1cc(Cn2ccnc2C)nn1	InChI=1S/C14H14FN5O/c1-10-16-5-6-19(10)8-12-9-20(18-17-12)13-4-3-11(15)7-14(13)21-2/h3-7,9H,8H2,1-2H3	VAYNXGJHBAWNOK-UHFFFAOYSA-N	396845	US9981950, Example 52	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1180							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396845	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396845&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870171	405266913							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796403	Cc1nccn1Cc1cn(nn1)-c1ccc(C)c(F)c1	InChI=1S/C14H14FN5/c1-10-3-4-13(7-14(10)15)20-9-12(17-18-20)8-19-6-5-16-11(19)2/h3-7,9H,8H2,1-2H3	VNHDHBHZGUTBRW-UHFFFAOYSA-N	396846	US9981950, Example 53	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26.5							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396846	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396846&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870125	405266914							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796404	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(C)c1	InChI=1S/C14H14FN5/c1-10-7-13(3-4-14(10)15)20-9-12(17-18-20)8-19-6-5-16-11(19)2/h3-7,9H,8H2,1-2H3	SUUBNQYDSCYRFB-UHFFFAOYSA-N	396847	US9981950, Example 54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5.32							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396847	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396847&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870127	405266915							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796405	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1	InChI=1S/C14H14ClN5/c1-10-7-13(3-4-14(10)15)20-9-12(17-18-20)8-19-6-5-16-11(19)2/h3-7,9H,8H2,1-2H3	UJRJRHMCPMPBNM-UHFFFAOYSA-N	396848	US9981950, Example 55	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.64							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396848	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396848&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870100	405266916							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796406	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)(F)F	InChI=1S/C14H11ClF3N5/c1-9-19-4-5-22(9)7-10-8-23(21-20-10)11-2-3-13(15)12(6-11)14(16,17)18/h2-6,8H,7H2,1H3	DRHMCKZRSIYNSH-UHFFFAOYSA-N	396849	US9981950, Example 56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11.9							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396849	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396849&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870142	405266917							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796407	Cc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C14H12F3N5O/c1-10-18-5-6-21(10)8-11-9-22(20-19-11)12-3-2-4-13(7-12)23-14(15,16)17/h2-7,9H,8H2,1H3	PSNQKKDWPZLWKY-UHFFFAOYSA-N	396850	US9981950, Example 57	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7.21							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396850	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396850&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870077	405266918							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796408	Cc1nccn1Cc1cn(nn1)-c1cccc(c1)C(F)(F)F	InChI=1S/C14H12F3N5/c1-10-18-5-6-21(10)8-12-9-22(20-19-12)13-4-2-3-11(7-13)14(15,16)17/h2-7,9H,8H2,1H3	VFTFBBYRZOXORC-UHFFFAOYSA-N	396851	US9981950, Example 58	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 17.4							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396851	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396851&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870061	405266919							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796409	Cc1nccn1Cc1cn(nn1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C14H12F3N5/c1-10-18-6-7-21(10)8-12-9-22(20-19-12)13-4-2-11(3-5-13)14(15,16)17/h2-7,9H,8H2,1H3	BLCNKRJMNGQWJU-UHFFFAOYSA-N	396852	US9981950, Example 59	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 46.0							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396852	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396852&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870137	405266920							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796410	Clc1ccc(c(Cl)c1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13Cl2N5/c16-11-3-4-14(13(17)7-11)22-9-12(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	RZJJYMUPIPAFHM-UHFFFAOYSA-N	396853	US9981950, Example 60	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1620							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396853	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396853&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870113	405266921							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796411	Fc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C15H13ClFN5/c16-13-4-3-12(7-14(13)17)22-9-11(19-20-22)8-21-6-5-18-15(21)10-1-2-10/h3-7,9-10H,1-2,8H2	BJBDOPNIPHEBTL-UHFFFAOYSA-N	396854	US9981950, Example 61	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 31.7							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396854	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396854&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870181	405266922							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796412	COc1cc(F)ccc1-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16FN5O/c1-23-15-8-12(17)4-5-14(15)22-10-13(19-20-22)9-21-7-6-18-16(21)11-2-3-11/h4-8,10-11H,2-3,9H2,1H3	VYUWAHTYQGQTNF-UHFFFAOYSA-N	396855	US9981950, Example 62	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3320							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396855	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396855&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870072	405266923							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796413	Cc1ccc(cc1F)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16FN5/c1-11-2-5-14(8-15(11)17)22-10-13(19-20-22)9-21-7-6-18-16(21)12-3-4-12/h2,5-8,10,12H,3-4,9H2,1H3	UZACFXZVMOVAMD-UHFFFAOYSA-N	396856	US9981950, Example 63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 87.1							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396856	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396856&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870169	405266924							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796414	Cc1cc(ccc1F)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16FN5/c1-11-8-14(4-5-15(11)17)22-10-13(19-20-22)9-21-7-6-18-16(21)12-2-3-12/h4-8,10,12H,2-3,9H2,1H3	BTLPJWLNOBZJLX-UHFFFAOYSA-N	396857	US9981950, Example 64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.1							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396857	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396857&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870104	405266925							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796415	Cc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H16ClN5/c1-11-8-14(4-5-15(11)17)22-10-13(19-20-22)9-21-7-6-18-16(21)12-2-3-12/h4-8,10,12H,2-3,9H2,1H3	LCRLHAYDJUFDBS-UHFFFAOYSA-N	396858	US9981950, Example 65	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12.4							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396858	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396858&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870096	405266926							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796416	FC(F)(F)c1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H13ClF3N5/c17-14-4-3-12(7-13(14)16(18,19)20)25-9-11(22-23-25)8-24-6-5-21-15(24)10-1-2-10/h3-7,9-10H,1-2,8H2	UULWSVSDBXUUNT-UHFFFAOYSA-N	396859	US9981950, Example 66	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 38.0							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396859	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396859&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870120	405266927							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796417	FC(F)(F)Oc1cccc(c1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5O/c17-16(18,19)25-14-3-1-2-13(8-14)24-10-12(21-22-24)9-23-7-6-20-15(23)11-4-5-11/h1-3,6-8,10-11H,4-5,9H2	BINRGTLWUGYJBP-UHFFFAOYSA-N	396860	US9981950, Example 67	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 34.5							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396860	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396860&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870183	405266928							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796418	FC(F)(F)c1cccc(c1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5/c17-16(18,19)12-2-1-3-14(8-12)24-10-13(21-22-24)9-23-7-6-20-15(23)11-4-5-11/h1-3,6-8,10-11H,4-5,9H2	IECCSHSCJSNUFX-UHFFFAOYSA-N	396861	US9981950, Example 68	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 91.6							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396861	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396861&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870160	405266929							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796419	FC(F)(F)c1ccc(cc1)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5/c17-16(18,19)12-3-5-14(6-4-12)24-10-13(21-22-24)9-23-8-7-20-15(23)11-1-2-11/h3-8,10-11H,1-2,9H2	NMIQLTRGPMQQII-UHFFFAOYSA-N	396862	US9981950, Example 69	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 173							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396862	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396862&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870170	405266930							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796420	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1	InChI=1S/C15H16ClN5/c1-3-15-17-6-7-20(15)9-12-10-21(19-18-12)13-4-5-14(16)11(2)8-13/h4-8,10H,3,9H2,1-2H3	HQQFCWPHPRSGTH-UHFFFAOYSA-N	396863	US9981950, Example 70	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.84							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396863&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870071	405266931							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796421	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(C)c1	InChI=1S/C16H18ClN5/c1-11(2)16-18-6-7-21(16)9-13-10-22(20-19-13)14-4-5-15(17)12(3)8-14/h4-8,10-11H,9H2,1-3H3	PNOCWPPPUIQTEQ-UHFFFAOYSA-N	396864	US9981950, Example 71	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.47							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396864	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396864&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870153	405266932							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796422	CCc1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C15H14F3N5O/c1-2-14-19-6-7-22(14)9-11-10-23(21-20-11)12-4-3-5-13(8-12)24-15(16,17)18/h3-8,10H,2,9H2,1H3	ZUBNWKBIEHKLQD-UHFFFAOYSA-N	396865	US9981950, Example 72	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11.4							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396865	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396865&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870182	405266933							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796423	CC(C)c1nccn1Cc1cn(nn1)-c1cccc(OC(F)(F)F)c1	InChI=1S/C16H16F3N5O/c1-11(2)15-20-6-7-23(15)9-12-10-24(22-21-12)13-4-3-5-14(8-13)25-16(17,18)19/h3-8,10-11H,9H2,1-2H3	DZEGAUUMJVVSNN-UHFFFAOYSA-N	396866	US9981950, Example 73	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 32.7							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396866&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870098	405266934							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796424	Cc1cc(ccc1Cl)-n1cc(Cn2ccnc2CCO)nn1	InChI=1S/C15H16ClN5O/c1-11-8-13(2-3-14(11)16)21-10-12(18-19-21)9-20-6-5-17-15(20)4-7-22/h2-3,5-6,8,10,22H,4,7,9H2,1H3	QGHUYWCWQWJAPH-UHFFFAOYSA-N	396867	US9981950, Example 74	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6.90							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396867&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870115	405266935							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796425	Cc1cc(ccc1Cl)-n1cc(Cn2ccnc2CCF)nn1	InChI=1S/C15H15ClFN5/c1-11-8-13(2-3-14(11)16)22-10-12(19-20-22)9-21-7-6-18-15(21)4-5-17/h2-3,6-8,10H,4-5,9H2,1H3	KOJCWZJFTKOHIH-UHFFFAOYSA-N	396868	US9981950, Example 75	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13.5							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396868&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870086	405266936							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796426	Cc1nccn1Cc1cn(nn1)-c1cccc(c1)C1CC1	InChI=1S/C16H17N5/c1-12-17-7-8-20(12)10-15-11-21(19-18-15)16-4-2-3-14(9-16)13-5-6-13/h2-4,7-9,11,13H,5-6,10H2,1H3	BCMMYCCUZMUCKE-UHFFFAOYSA-N	396869	US9981950, Example 76	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.9							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396869&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870159	405266937							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796427	Cc1nccn1Cc1cn(nn1)-c1cccc(c1)S(C)(=O)=O	InChI=1S/C14H15N5O2S/c1-11-15-6-7-18(11)9-12-10-19(17-16-12)13-4-3-5-14(8-13)22(2,20)21/h3-8,10H,9H2,1-2H3	FTODECXLANNKPC-UHFFFAOYSA-N	396870	US9981950, Example 77	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 615							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396870&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870110	405266938							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796428	OCCc1nccn1Cc1cn(nn1)-c1cccc(c1)C1CC1	InChI=1S/C17H19N5O/c23-9-6-17-18-7-8-21(17)11-15-12-22(20-19-15)16-3-1-2-14(10-16)13-4-5-13/h1-3,7-8,10,12-13,23H,4-6,9,11H2	QUXRRGHMYGOPOY-UHFFFAOYSA-N	396871	US9981950, Example 78	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 41.1							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396871	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870059	405266939							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796429	CS(=O)(=O)c1cccc(c1)-n1cc(Cn2ccnc2CCO)nn1	InChI=1S/C15H17N5O3S/c1-24(22,23)14-4-2-3-13(9-14)20-11-12(17-18-20)10-19-7-6-16-15(19)5-8-21/h2-4,6-7,9,11,21H,5,8,10H2,1H3	JOCVQBDURVHERC-UHFFFAOYSA-N	396872	US9981950, Example 79	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1400							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396872&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870121	405266940							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796430	CS(=O)(=O)c1cccc(c1)-n1cc(Cn2ccnc2CCF)nn1	InChI=1S/C15H16FN5O2S/c1-24(22,23)14-4-2-3-13(9-14)21-11-12(18-19-21)10-20-8-7-17-15(20)5-6-16/h2-4,7-9,11H,5-6,10H2,1H3	KLOSGRVATVPBIQ-UHFFFAOYSA-N	396873	US9981950, Example 80	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2680							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870126	405266941							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796431	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C14H12F3N5/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-13(15)12(6-11)14(16)17/h2-6,8,14H,7H2,1H3	QSKZBFJMOFMZSF-UHFFFAOYSA-N	396874	US9981950, Example 81	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.83							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396874&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870064	405266942							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796432	FC(F)c1cc(ccc1F)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14F3N5/c17-14-4-3-12(7-13(14)15(18)19)24-9-11(21-22-24)8-23-6-5-20-16(23)10-1-2-10/h3-7,9-10,15H,1-2,8H2	XRNXEVVICQRAAE-UHFFFAOYSA-N	396875	US9981950, Example 82	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16.2							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396875&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870105	405266943							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796433	CCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C15H14F3N5/c1-2-14-19-5-6-22(14)8-10-9-23(21-20-10)11-3-4-13(16)12(7-11)15(17)18/h3-7,9,15H,2,8H2,1H3	PKKCOOQFVZMCHD-UHFFFAOYSA-N	396876	US9981950, Example 83	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.11							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870146	405266944							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796434	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H16F3N5/c1-10(2)16-20-5-6-23(16)8-11-9-24(22-21-11)12-3-4-14(17)13(7-12)15(18)19/h3-7,9-10,15H,8H2,1-2H3	RHCWEINUWQCGDI-UHFFFAOYSA-N	396877	US9981950, Example 84	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11.0							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396877&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870079	405266945							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796435	CCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C16H16F3N5/c1-2-3-15-20-6-7-23(15)9-11-10-24(22-21-11)12-4-5-14(17)13(8-12)16(18)19/h4-8,10,16H,2-3,9H2,1H3	APCKLHZSVVXCSJ-UHFFFAOYSA-N	396878	US9981950, Example 85	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.40							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396878	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396878&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870139	405266946							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796436	CCCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C17H18F3N5/c1-2-3-4-16-21-7-8-24(16)10-12-11-25(23-22-12)13-5-6-15(18)14(9-13)17(19)20/h5-9,11,17H,2-4,10H2,1H3	ILHXDJNKXGVDCA-UHFFFAOYSA-N	396879	US9981950, Example 86	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.29							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396879	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396879&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870123	405266947							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796437	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C17H18F3N5/c1-17(2,3)16-21-6-7-24(16)9-11-10-25(23-22-11)12-4-5-14(18)13(8-12)15(19)20/h4-8,10,15H,9H2,1-3H3	PVCPERVVEUJKJP-UHFFFAOYSA-N	396880	US9981950, Example 87	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 131							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396880	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396880&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870099	405266948							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796438	OCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C15H14F3N5O/c16-13-2-1-11(7-12(13)15(17)18)23-9-10(20-21-23)8-22-5-4-19-14(22)3-6-24/h1-2,4-5,7,9,15,24H,3,6,8H2	WAGGNWZFAHXBMP-UHFFFAOYSA-N	396881	US9981950, Example 88	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 14.5							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396881	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396881&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870161	405266949							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796439	Cc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C14H12ClF2N5/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-13(15)12(6-11)14(16)17/h2-6,8,14H,7H2,1H3	QLHBDCCSPGVPTO-UHFFFAOYSA-N	396882	US9981950, Example 89	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.37							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396882	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396882&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870135	405266950							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796440	FC(F)c1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14ClF2N5/c17-14-4-3-12(7-13(14)15(18)19)24-9-11(21-22-24)8-23-6-5-20-16(23)10-1-2-10/h3-7,9-10,15H,1-2,8H2	JLSQSDCBSROECG-UHFFFAOYSA-N	396883	US9981950, Example 90	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.4							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396883	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396883&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870075	405266951							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796441	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C15H14ClF2N5/c1-2-14-19-5-6-22(14)8-10-9-23(21-20-10)11-3-4-13(16)12(7-11)15(17)18/h3-7,9,15H,2,8H2,1H3	CIAAWOPCBYSYLC-UHFFFAOYSA-N	396884	US9981950, Example 91	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2.43							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396884	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396884&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870069	405266952							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796442	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C16H16ClF2N5/c1-10(2)16-20-5-6-23(16)8-11-9-24(22-21-11)12-3-4-14(17)13(7-12)15(18)19/h3-7,9-10,15H,8H2,1-2H3	PEDNWEQKMIWGBJ-UHFFFAOYSA-N	396885	US9981950, Example 92	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5.24							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396885	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396885&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870070	405266953							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796443	FC(F)Oc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14ClF2N5O/c17-13-4-3-12(7-14(13)25-16(18)19)24-9-11(21-22-24)8-23-6-5-20-15(23)10-1-2-10/h3-7,9-10,16H,1-2,8H2	BHASKRVNSLNZGW-UHFFFAOYSA-N	396887	US9981950, Example 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.20							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396887	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396887&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870162	405266955							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796444	FC(F)Oc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1	InChI=1S/C16H14ClF2N5O/c17-13-4-3-12(7-14(13)25-16(18)19)24-9-11(21-22-24)8-23-6-5-20-15(23)10-1-2-10/h3-7,9-10,16H,1-2,8H2	BHASKRVNSLNZGW-UHFFFAOYSA-N	396887	US9981950, Example 94	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.91							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396887	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396887&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870162	405266955							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796445	CC(C)(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C17H18ClF2N5O/c1-17(2,3)15-21-6-7-24(15)9-11-10-25(23-22-11)12-4-5-13(18)14(8-12)26-16(19)20/h4-8,10,16H,9H2,1-3H3	NXVWMYHMJCGROD-UHFFFAOYSA-N	396888	US9981950, Example 95	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 72.9							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396888	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396888&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870141	405266956							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796446	CCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H14ClF2N5O/c1-2-14-19-5-6-22(14)8-10-9-23(21-20-10)11-3-4-12(16)13(7-11)24-15(17)18/h3-7,9,15H,2,8H2,1H3	RPRRSXXASCSWCX-UHFFFAOYSA-N	396889	US9981950, Example 96	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.60							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396889	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396889&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870179	405266957							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796447	CC(C)c1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C16H16ClF2N5O/c1-10(2)15-20-5-6-23(15)8-11-9-24(22-21-11)12-3-4-13(17)14(7-12)25-16(18)19/h3-7,9-10,16H,8H2,1-2H3	OSODAZMEELVOGC-UHFFFAOYSA-N	396890	US9981950, Example 97	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3.12							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396890	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396890&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870093	405266958							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796448	OCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H14ClF2N5O2/c16-12-2-1-11(7-13(12)25-15(17)18)23-9-10(20-21-23)8-22-5-4-19-14(22)3-6-24/h1-2,4-5,7,9,15,24H,3,6,8H2	SDYVDXMMCZXDQX-UHFFFAOYSA-N	396891	US9981950, Example 98	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2.26							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396891	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396891&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870067	405266959							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796449	FCCc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C15H13ClF3N5O/c16-12-2-1-11(7-13(12)25-15(18)19)24-9-10(21-22-24)8-23-6-5-20-14(23)3-4-17/h1-2,5-7,9,15H,3-4,8H2	QFNOXQXTBCOOIT-UHFFFAOYSA-N	396892	US9981950, Example 99	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6.02							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396892	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396892&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870165	405266960							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796450	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C14H12F3N5O/c1-9-18-4-5-21(9)7-10-8-22(20-19-10)11-2-3-12(15)13(6-11)23-14(16)17/h2-6,8,14H,7H2,1H3	OBJSITFIPOKILU-UHFFFAOYSA-N	396893	US9981950, Example 100	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1.90							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396893	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396893&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870087	405266961							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796451	OCCc1nccn1Cc1cn(nn1)-c1ccc(F)c(OC(F)F)c1	InChI=1S/C15H14F3N5O2/c16-12-2-1-11(7-13(12)25-15(17)18)23-9-10(20-21-23)8-22-5-4-19-14(22)3-6-24/h1-2,4-5,7,9,15,24H,3,6,8H2	CQYRYSJJBAIWRQ-UHFFFAOYSA-N	396894	US9981950, Example 101	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.26							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396894	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396894&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870066	405266962							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796452	Cc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C14H12F3N5/c1-9-18-2-3-21(9)7-12-8-22(20-19-12)13-5-10(14(16)17)4-11(15)6-13/h2-6,8,14H,7H2,1H3	OCGOMHKIACWSMG-UHFFFAOYSA-N	396895	US9981950, Example 102	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 25.9							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396895	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396895&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870138	405266963							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796453	OCCc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C15H14F3N5O/c16-11-5-10(15(17)18)6-13(7-11)23-9-12(20-21-23)8-22-3-2-19-14(22)1-4-24/h2-3,5-7,9,15,24H,1,4,8H2	XEAHOSRXLJEYBK-UHFFFAOYSA-N	396896	US9981950, Example 103	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 136							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396896	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396896&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870136	405266964							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796454	FCCc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C15H13F4N5/c16-2-1-14-20-3-4-23(14)8-12-9-24(22-21-12)13-6-10(15(18)19)5-11(17)7-13/h3-7,9,15H,1-2,8H2	UEBVHKXENWPKIG-UHFFFAOYSA-N	398600	US10323021, Example 104	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 186							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398600	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398600&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870065	405258646							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796455	Cc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(C)(F)F	InChI=1S/C15H14F3N5/c1-10-19-5-6-22(10)8-11-9-23(21-20-11)12-3-4-14(16)13(7-12)15(2,17)18/h3-7,9H,8H2,1-2H3	UJPVZTKYGGHGLB-UHFFFAOYSA-N	396898	US9981950, Example 105	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.05							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396898	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396898&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870130	405266966							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796456	CC(F)(F)c1cc(ccc1F)-n1cc(Cn2ccnc2CCO)nn1	InChI=1S/C16H16F3N5O/c1-16(18,19)13-8-12(2-3-14(13)17)24-10-11(21-22-24)9-23-6-5-20-15(23)4-7-25/h2-3,5-6,8,10,25H,4,7,9H2,1H3	QULVTNJBHGMPJK-UHFFFAOYSA-N	396899	US9981950, Example 106	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 8.08							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396899	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396899&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870134	405266967							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796457	Cn1nccc1Cc1cn(nn1)-c1ccc(F)c(Cl)c1	InChI=1S/C13H11ClFN5/c1-19-10(4-5-16-19)6-9-8-20(18-17-9)11-2-3-13(15)12(14)7-11/h2-5,7-8H,6H2,1H3	OMQQLDITRYIEHZ-UHFFFAOYSA-N	396900	US9981950, Example 109	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4320							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396900	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396900&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870060	405266968							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796458	Nc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(OC(F)F)c1	InChI=1S/C13H11ClF2N6O/c14-10-2-1-9(5-11(10)23-12(15)16)22-7-8(19-20-22)6-21-4-3-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	BRINTJVXMVTOJY-UHFFFAOYSA-N	396901	US9981950, Example 110	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.520							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396901	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396901&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870090	405266969							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796459	Nc1nccn1Cc1cn(nn1)-c1cc(F)cc(c1)C(F)F	InChI=1S/C13H11F3N6/c14-9-3-8(12(15)16)4-11(5-9)22-7-10(19-20-22)6-21-2-1-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	XNKTWVPPPLRTKJ-UHFFFAOYSA-N	396902	US9981950, Example 111	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2.13							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396902	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396902&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870092	405266970							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796460	Nc1nccn1Cc1cn(nn1)-c1ccc(Cl)c(c1)C(F)F	InChI=1S/C13H11ClF2N6/c14-11-2-1-9(5-10(11)12(15)16)22-7-8(19-20-22)6-21-4-3-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	ZCROGTMUHYRBRR-UHFFFAOYSA-N	396903	US9981950, Example 113A	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.650							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396903	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396903&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870116	405266971							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796461	Nc1nccn1Cc1cn(nn1)-c1ccc(F)c(c1)C(F)F	InChI=1S/C13H11F3N6/c14-11-2-1-9(5-10(11)12(15)16)22-7-8(19-20-22)6-21-4-3-18-13(21)17/h1-5,7,12H,6H2,(H2,17,18)	UZRIQFGTVHJEPZ-UHFFFAOYSA-N	396904	US9981950, Example 113B	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.480							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396904	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396904&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870083	405266972							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796462	CC(F)(F)c1cc(ccc1Cl)-n1cc(Cn2ccnc2N)nn1	InChI=1S/C14H13ClF2N6/c1-14(16,17)11-6-10(2-3-12(11)15)23-8-9(20-21-23)7-22-5-4-19-13(22)18/h2-6,8H,7H2,1H3,(H2,18,19)	GAPPKFOAUJZOIJ-UHFFFAOYSA-N	398608	US10323021, Example 114	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.510							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398608	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398608&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			138718719	405258654							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796463	FC(F)c1cc(ccc1F)-n1cc(Cc2cc[nH]n2)nn1	InChI=1S/C13H10F3N5/c14-12-2-1-10(6-11(12)13(15)16)21-7-9(19-20-21)5-8-3-4-17-18-8/h1-4,6-7,13H,5H2,(H,17,18)	XCUYCJFGWDLGRI-UHFFFAOYSA-N	396906	US9981950, Example 115	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 236							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396906	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396906&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870128	405266974							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796464	Cc1ccc(cc1)C(=O)c1nccn1Cc1cn(nn1)-c1ccc(Cl)cc1	InChI=1S/C20H16ClN5O/c1-14-2-4-15(5-3-14)19(27)20-22-10-11-25(20)12-17-13-26(24-23-17)18-8-6-16(21)7-9-18/h2-11,13H,12H2,1H3	FMXPLHPTIXIQOD-UHFFFAOYSA-N	396907	US9981950, Example 116	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>5000							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396907	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396907&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870082	405266975							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796465	Cc1nc2ccccc2n1Cc1cn(nn1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C17H13Cl2N5/c1-11-20-16-4-2-3-5-17(16)23(11)9-12-10-24(22-21-12)13-6-7-14(18)15(19)8-13/h2-8,10H,9H2,1H3	NBDNSJRTVZQEOU-UHFFFAOYSA-N	396908	US9981950, Example 117	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 141							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=396908	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=396908&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870085	405266976							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
796466	OCCc1nccn1Cc1cn(nn1)-c1ccc(cc1)S(F)(F)(F)(F)F	InChI=1S/C14H14F5N5OS/c15-26(16,17,18,19)13-3-1-12(2-4-13)24-10-11(21-22-24)9-23-7-6-20-14(23)5-8-25/h1-4,6-7,10,25H,5,8-9H2	KSYNJOQTXRFSTA-UHFFFAOYSA-N	398611	US10323021, Example 118	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 263							US Patent		10.7270/Q2JW8H7X		aid1799209	US10323021	Schindler, R; Lankau, H; Hofgen, N; Egerland, U; Langen, B; Dost, R; Ward, S	6/18/2019	5/10/2020	Janssen Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398611	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398611&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118870089	405258656							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
816324	COc1cc(ncc1C#N)C(=O)NC1CCN(C[C@H](O)c2ccc3C(=O)OCc3c2C)CC1 |r|	InChI=1S/C24H26N4O5/c1-14-17(3-4-18-19(14)13-33-24(18)31)21(29)12-28-7-5-16(6-8-28)27-23(30)20-9-22(32-2)15(10-25)11-26-20/h3-4,9,11,16,21,29H,5-8,12-13H2,1-2H3,(H,27,30)	PJJXLIVFRBOUIZ-UHFFFAOYSA-N	408663	US10364234, Example 1::US10759788, Example 1::(R)-5-cyano-N-(1-(2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydroisobenzofuran-5-yl)ethyl)piperidin-4-yl)-4-methoxypicolinamide	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 43700							US Patent		10.7270/Q2P271GV		aid1803730	US10364234	Li, X; Dong, Q; Sun, P	7/30/2019	6/29/2020	Jiangsu Hengrui Medicine	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=408663	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=408663&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			132005519	406799297							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822046	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1 |r,wU:4.3,wD:7.10,(-7.95,2.08,;-6.62,2.85,;-6.62,4.39,;-7.95,3.62,;-5.29,2.08,;-3.95,2.85,;-2.62,2.08,;-2.62,.54,;-3.95,-.23,;-5.29,.54,;-1.28,-.23,;.05,.54,;.05,2.08,;1.38,2.85,;2.72,2.08,;4.18,2.56,;5.09,1.31,;4.18,.07,;4.58,-1.42,;3.49,-2.51,;3.89,-4,;5.38,-4.39,;6.47,-3.31,;7.95,-3.7,;6.07,-1.82,;2.72,.54,;1.38,-.23,)|	InChI=1S/C21H25ClN4O/c1-21(2,27)15-6-8-17(9-7-15)24-19-10-11-20-23-13-18(26(20)25-19)14-4-3-5-16(22)12-14/h3-5,10-13,15,17,27H,6-9H2,1-2H3,(H,24,25)	BZNALBIJBHYZPW-UHFFFAOYSA-N	242380	US10047093, 8-37::US9416132, 8-37::US10392392, Example 8-37::US10875864, EX. 8-37	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242380	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242380&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598035	341094631							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822047	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1 |r,wU:1.0,wD:4.7,(-7.29,3.62,;-5.95,2.85,;-4.62,3.62,;-3.29,2.85,;-3.29,1.31,;-4.62,.54,;-5.95,1.31,;-1.95,.54,;-.62,1.31,;-.62,2.85,;.72,3.62,;2.05,2.85,;3.51,3.33,;4.42,2.08,;3.51,.84,;3.91,-.65,;2.82,-1.74,;3.22,-3.23,;4.71,-3.62,;5.8,-2.54,;7.29,-2.93,;5.4,-1.05,;2.05,1.31,;.72,.54,)|	InChI=1S/C18H19ClN4O/c19-13-3-1-2-12(10-13)16-11-20-18-9-8-17(22-23(16)18)21-14-4-6-15(24)7-5-14/h1-3,8-11,14-15,24H,4-7H2,(H,21,22)	OKAUIWRBORRFHW-UHFFFAOYSA-N	242378	US10047093, 8-35::US9416132, 8-35::US10392392, Example 8-35::US10875864, EX. 8-35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242378	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242378&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598229	341094629							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822048	OC[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1 |r,wU:2.1,wD:5.8,(-8,2.88,;-6.67,3.65,;-5.33,2.88,;-3.95,3.62,;-2.62,2.85,;-2.62,1.31,;-3.95,.54,;-5.29,1.31,;-1.28,.54,;.05,1.31,;.05,2.85,;1.38,3.62,;2.72,2.85,;4.18,3.33,;5.09,2.08,;4.18,.84,;4.58,-.65,;3.49,-1.74,;3.89,-3.23,;5.38,-3.62,;6.47,-2.54,;7.95,-2.93,;6.07,-1.05,;2.72,1.31,;1.38,.54,)|	InChI=1S/C19H21ClN4O/c20-15-3-1-2-14(10-15)17-11-21-24-9-8-18(23-19(17)24)22-16-6-4-13(12-25)5-7-16/h1-3,8-11,13,16,25H,4-7,12H2,(H,22,23)	VSCPITUJYKTOSN-UHFFFAOYSA-N	228355	US10047093, 8-64::US10392392, Example 8-64::US10875864, EX. 8-64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228355	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228355&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66592626	375077250							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822049	Clc1cccc(c1)-c1cnc2ccc(NC3CCOCC3)nn12	InChI=1S/C17H17ClN4O/c18-13-3-1-2-12(10-13)15-11-19-17-5-4-16(21-22(15)17)20-14-6-8-23-9-7-14/h1-5,10-11,14H,6-9H2,(H,20,21)	OEIWNDGDGDPXIO-UHFFFAOYSA-N	35052	K00152::US10047093, 8-39::US9416132, 8-39::US10392392, Example 8-39::US10875864, EX. 8-39	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35052	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35052&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			6419807	85753134							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822050	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 |r,wU:7.10,wD:4.3,(-8.7,2.48,;-7.36,3.25,;-7.36,4.79,;-8.7,4.02,;-6.03,2.48,;-6.03,.94,;-4.7,.17,;-3.36,.94,;-3.36,2.48,;-4.7,3.25,;-2.03,.17,;-.69,.94,;-.69,2.48,;.64,3.25,;1.97,2.48,;3.44,2.96,;4.34,1.71,;3.44,.47,;3.84,-1.02,;2.75,-2.11,;3.15,-3.6,;4.63,-4,;5.82,-2.9,;5.32,-1.42,;7.31,-3.28,;8.8,-3.66,;6.93,-4.77,;7.69,-1.79,;1.97,.94,;.64,.17,)|	InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)	XRNVABDYQLHODA-UHFFFAOYSA-N	242374	US10047093, 8-31::US9416132, 8-31::US10392392, Example 8-31::US10875864, EX. 8-31	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242374	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242374&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598080	341094625							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822051	C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 |r,wU:5.8,1.0,wD:1.1,(-7.36,4.3,;-6.59,2.97,;-8.13,2.97,;-6.59,1.43,;-5.26,.66,;-3.93,1.43,;-3.93,2.97,;-5.26,3.74,;-2.59,.66,;-1.26,1.43,;-1.26,2.97,;.08,3.74,;1.41,2.97,;2.87,3.45,;3.78,2.2,;2.87,.96,;3.27,-.53,;2.18,-1.62,;2.58,-3.11,;4.07,-3.51,;5.25,-2.41,;4.76,-.93,;6.75,-2.79,;8.24,-3.17,;6.36,-4.28,;7.13,-1.3,;1.41,1.43,;.08,.66,)|	InChI=1S/C20H21F3N4O/c1-19(28)9-7-15(8-10-19)25-17-5-6-18-24-12-16(27(18)26-17)13-3-2-4-14(11-13)20(21,22)23/h2-6,11-12,15,28H,7-10H2,1H3,(H,25,26)	SZDYHSAHSPZDEB-UHFFFAOYSA-N	242373	US10047093, 8-30::US9416132, 8-30::US10392392, Example 8-30::US10875864, EX. 8-30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242373	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242373&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598034	341094624							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822052	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1 |r,wU:4.7,wD:1.0,(-8.03,4.02,;-6.7,3.25,;-6.7,1.71,;-5.36,.94,;-4.03,1.71,;-4.03,3.25,;-5.36,4.02,;-2.7,.94,;-1.36,1.71,;-1.36,3.25,;-.03,4.02,;1.31,3.25,;2.77,3.73,;3.68,2.48,;2.77,1.24,;3.17,-.25,;2.08,-1.34,;2.48,-2.83,;3.97,-3.23,;5.15,-2.13,;4.66,-.65,;6.64,-2.51,;8.14,-2.89,;6.26,-4,;7.03,-1.02,;1.31,1.71,;-.03,.94,)|	InChI=1S/C19H19F3N4O/c20-19(21,22)13-3-1-2-12(10-13)16-11-23-18-9-8-17(25-26(16)18)24-14-4-6-15(27)7-5-14/h1-3,8-11,14-15,27H,4-7H2,(H,24,25)	OIWKVZIBVNRNOJ-UHFFFAOYSA-N	242372	US10047093, 8-29::US9416132, 8-29::US10392392, Example 8-29::US10875864, EX. 8-29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242372	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242372&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598158	341094623							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822053	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1 |r,wU:7.10,wD:4.3,(-9.24,2.08,;-7.91,2.85,;-7.91,4.39,;-9.24,3.62,;-6.57,2.08,;-6.57,.54,;-5.24,-.23,;-3.91,.54,;-3.91,2.08,;-5.24,2.85,;-2.57,-.23,;-1.24,.54,;-1.24,2.08,;.09,2.85,;1.43,2.08,;2.89,2.56,;3.8,1.31,;2.89,.07,;3.29,-1.42,;2.2,-2.51,;2.6,-4,;4.09,-4.39,;5.23,-3.32,;6.72,-3.72,;7.81,-2.63,;8.9,-1.54,;8.9,-3.72,;6.72,-1.54,;4.78,-1.82,;1.43,.54,;.09,-.23,)|	InChI=1S/C22H25F3N4O2/c1-21(2,30)15-6-8-16(9-7-15)27-19-10-11-20-26-13-18(29(20)28-19)14-4-3-5-17(12-14)31-22(23,24)25/h3-5,10-13,15-16,30H,6-9H2,1-2H3,(H,27,28)	NMIBDYYYDQCKBY-UHFFFAOYSA-N	242354	US10047093, 8-10::US9416132, 8-10::US10392392, Example 8-10::US10875864, EX. 8-10	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242354	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242354&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597963	341094605							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822054	C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1 |r,wU:1.1,wD:5.8,1.0,(-7.91,3.91,;-7.14,2.57,;-8.68,2.57,;-5.8,3.34,;-4.47,2.57,;-4.47,1.03,;-5.8,.26,;-7.14,1.03,;-3.14,.26,;-1.8,1.03,;-1.8,2.57,;-.47,3.34,;.86,2.57,;2.33,3.05,;3.23,1.8,;2.33,.56,;2.73,-.93,;1.64,-2.02,;2.04,-3.51,;3.52,-3.91,;4.67,-2.83,;6.15,-3.23,;7.24,-2.14,;8.33,-1.05,;8.33,-3.23,;6.15,-1.05,;4.22,-1.33,;.86,1.03,;-.47,.26,)|	InChI=1S/C20H21F3N4O2/c1-19(28)9-7-14(8-10-19)25-17-5-6-18-24-12-16(27(18)26-17)13-3-2-4-15(11-13)29-20(21,22)23/h2-6,11-12,14,28H,7-10H2,1H3,(H,25,26)	YVGAENJCKBRBJB-UHFFFAOYSA-N	242353	US10047093, 8-9::US9416132, 8-9::US10392392, Example 8-9::US10875864, EX. 8-9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242353	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242353&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597961	341094604							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822055	OC[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1 |r,wU:2.1,wD:5.8,(-7.96,5.19,;-7.96,3.65,;-6.62,2.88,;-5.24,3.62,;-3.91,2.85,;-3.91,1.31,;-5.24,.54,;-6.57,1.31,;-2.57,.54,;-1.24,1.31,;-1.24,2.85,;.09,3.62,;1.43,2.85,;2.89,3.33,;3.8,2.08,;2.89,.84,;3.29,-.65,;2.2,-1.74,;2.6,-3.23,;4.09,-3.62,;5.23,-2.55,;6.72,-2.95,;7.81,-1.86,;8.9,-.77,;8.9,-2.95,;6.72,-.77,;4.78,-1.05,;1.43,1.31,;.09,.54,)|	InChI=1S/C20H21F3N4O2/c21-20(22,23)29-16-3-1-2-14(10-16)17-11-24-19-9-8-18(26-27(17)19)25-15-6-4-13(12-28)5-7-15/h1-3,8-11,13,15,28H,4-7,12H2,(H,25,26)	ZFSDGASFASUELO-UHFFFAOYSA-N	228294	US10047093, 8-11::US10392392, Example 8-11::US10875864, EX. 8-11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228294	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228294&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			89462288	375077207							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822056	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1 |r,wU:4.3,wD:7.10,(.73,-52.37,;1.51,-51.04,;-.05,-51.03,;1.52,-49.51,;2.84,-51.82,;4.18,-51.06,;5.51,-51.82,;5.5,-53.37,;4.18,-54.14,;2.84,-53.36,;6.84,-54.14,;8.17,-53.37,;8.17,-51.83,;9.5,-51.05,;10.83,-51.83,;12.29,-51.35,;13.2,-52.6,;12.29,-53.84,;13.05,-55.17,;12.26,-56.5,;13.02,-57.84,;14.56,-57.86,;15.34,-56.52,;16.88,-56.53,;14.58,-55.19,;10.83,-53.37,;9.5,-54.13,)|	InChI=1S/C21H25ClN4O/c1-21(2,27)15-6-8-17(9-7-15)24-19-10-11-26-20(25-19)18(13-23-26)14-4-3-5-16(22)12-14/h3-5,10-13,15,17,27H,6-9H2,1-2H3,(H,24,25)	QWEBKNRGVXJIKS-UHFFFAOYSA-N	50043697	US10047093, 8-63::CHEMBL3355987::US9416132, 8-63::US10392392, Example 8-63::US10875864, EX. 8-63	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043697	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043697&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597997	103975081		CHEMBL3355987					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822057	O[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1 |r,wU:1.0,wD:4.7,(12.63,-23.03,;13.97,-23.8,;15.3,-23.04,;16.63,-23.8,;16.63,-25.35,;15.3,-26.12,;13.97,-25.34,;17.96,-26.12,;19.3,-25.35,;19.3,-23.81,;20.63,-23.03,;21.95,-23.81,;23.42,-23.33,;24.33,-24.58,;23.42,-25.83,;24.18,-27.16,;23.39,-28.48,;24.15,-29.82,;25.69,-29.84,;26.47,-28.5,;25.71,-27.17,;28.01,-28.51,;28.77,-29.85,;28.79,-27.18,;29.55,-28.51,;21.95,-25.35,;20.63,-26.11,)|	InChI=1S/C19H19F3N4O/c20-19(21,22)13-3-1-2-12(10-13)16-11-23-26-9-8-17(25-18(16)26)24-14-4-6-15(27)7-5-14/h1-3,8-11,14-15,27H,4-7H2,(H,24,25)	DFHQXRLKAFZKPB-UHFFFAOYSA-N	50043674	US10047093, 8-54::CHEMBL3355550::US9416132, 8-54::US10392392, Example 8-54::US10875864, EX. 8-54	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043674	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043674&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598095	103975058		CHEMBL3355550					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822058	CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1 |r,wU:4.3,wD:7.10,(51,-26.01,;51.77,-24.69,;50.23,-24.68,;51.78,-23.15,;53.11,-25.47,;54.44,-24.7,;55.77,-25.47,;55.77,-27.01,;54.44,-27.78,;53.11,-27.01,;57.1,-27.78,;58.44,-27.01,;58.44,-25.47,;59.76,-24.69,;61.09,-25.47,;62.56,-24.99,;63.46,-26.24,;62.56,-27.49,;63.31,-28.82,;62.53,-30.15,;63.28,-31.49,;64.82,-31.5,;65.61,-30.17,;64.85,-28.83,;67.15,-30.18,;67.91,-31.51,;67.92,-28.85,;68.68,-30.17,;61.09,-27.01,;59.76,-27.77,)|	InChI=1S/C22H25F3N4O/c1-21(2,30)15-6-8-17(9-7-15)27-19-10-11-29-20(28-19)18(13-26-29)14-4-3-5-16(12-14)22(23,24)25/h3-5,10-13,15,17,30H,6-9H2,1-2H3,(H,27,28)	FSQNGXYJUMATLF-UHFFFAOYSA-N	50043662	US10047093, 8-56::CHEMBL3355552::US9416132, 8-56::US10392392, Example 8-56::US10875864, EX. 8-56	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043662	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043662&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598153	103975046		CHEMBL3355552					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822059	O[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(OC(F)(F)F)c3)c2n1 |r,wU:1.0,wD:4.7,(50.22,-3.1,;51.55,-3.88,;52.88,-3.11,;54.21,-3.88,;54.21,-5.42,;52.88,-6.19,;51.55,-5.42,;55.54,-6.19,;56.88,-5.42,;56.88,-3.88,;58.21,-3.1,;59.54,-3.88,;61,-3.4,;61.91,-4.65,;61,-5.9,;61.76,-7.23,;60.97,-8.56,;61.73,-9.9,;63.27,-9.91,;64.05,-8.58,;65.59,-8.59,;66.35,-9.93,;67.89,-9.94,;65.57,-11.25,;67.03,-11.3,;63.29,-7.24,;59.54,-5.42,;58.21,-6.18,)|	InChI=1S/C19H19F3N4O2/c20-19(21,22)28-15-3-1-2-12(10-15)16-11-23-26-9-8-17(25-18(16)26)24-13-4-6-14(27)7-5-13/h1-3,8-11,13-14,27H,4-7H2,(H,24,25)	ATMAGFPFVYJWHA-UHFFFAOYSA-N	50043690	US10047093, 8-46::CHEMBL3355544::US9416132, 8-46::US10392392, Example 8-46::US10875864, EX. 8-46	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043690	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043690&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66597981	103975074		CHEMBL3355544					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822060	O[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1 |r,wU:4.7,wD:1.0,(-8.57,3.62,;-7.24,2.85,;-7.24,1.31,;-5.91,.54,;-4.57,1.31,;-4.57,2.85,;-5.91,3.62,;-3.24,.54,;-1.91,1.31,;-1.91,2.85,;-.57,3.62,;.76,2.85,;2.23,3.33,;3.13,2.08,;2.23,.84,;2.62,-.65,;1.54,-1.74,;1.93,-3.23,;3.42,-3.62,;4.56,-2.55,;6.05,-2.95,;7.14,-1.86,;8.23,-.77,;8.23,-2.95,;6.05,-.77,;4.11,-1.05,;.76,1.31,;-.57,.54,)|	InChI=1S/C19H19F3N4O2/c20-19(21,22)28-15-3-1-2-12(10-15)16-11-23-18-9-8-17(25-26(16)18)24-13-4-6-14(27)7-5-13/h1-3,8-11,13-14,27H,4-7H2,(H,24,25)	LOMZUAFMSBAHAU-UHFFFAOYSA-N	242345	US10047093, 8-1::US9416132, 8-1::US10392392, Example 8-1::US10875864, EX. 8-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 16000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242345	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242345&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			24996072	341094596							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
822061	FC(F)(F)Oc1cccc(c1)-c1cnc2ccc(NCC3CCS(=O)(=O)CC3)nn12	InChI=1S/C19H19F3N4O3S/c20-19(21,22)29-15-3-1-2-14(10-15)16-12-24-18-5-4-17(25-26(16)18)23-11-13-6-8-30(27,28)9-7-13/h1-5,10,12-13H,6-9,11H2,(H,23,25)	JABDFUFLQGAQCU-UHFFFAOYSA-N	242356	US10047093, 8-13::US9416132, 8-13::US10392392, Example 8-13::US10875864, EX. 8-13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10000							US Patent		10.7270/Q27P91RC		aid1803781	US10392392	Xu, Y; Brenning, BG; Kultgen, SG; Liu, X; Saunders, MD; Ho, K	8/27/2019	7/20/2020	Tolero Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242356	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242356&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			66598170	341094607							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825443	FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-3-13(4-2-12)19(22,23)24)10-30-7-5-14(6-8-30)28-16-15-9-27-29-17(15)26-11-25-16/h1-4,9,11,14H,5-8,10H2,(H2,25,26,27,28,29)	GXJBVCKDEHELEL-UHFFFAOYSA-N	280739	US10030026, Compound LX-1::US10221182, Compound LX-1::US9968610, Compound LX-1::US10294230, Compound LX-1::US10420768, Compound LX-1::US10584127, Compound LX-1::US11136328, Compound LX-1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=280739	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=280739&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11959514	378162168							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825445	FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ccc12)c1ccc(Cl)cn1	InChI=1S/C18H19ClF2N6/c19-12-1-2-15(23-9-12)18(20,21)10-27-7-4-13(5-8-27)26-17-14-3-6-22-16(14)24-11-25-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,22,24,25,26)	QOTIEMUIZUBYME-UHFFFAOYSA-N	287587	US9567341, Compound C-3::US9968610, Compound C-3::US10420768, Compound C-3::US11752155, Compound C-3A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7000							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287587	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287587&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938577	378171154							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825447	Cc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H22F2N6/c1-13-2-3-16(23-10-13)19(20,21)11-27-8-5-14(6-9-27)26-18-15-4-7-22-17(15)24-12-25-18/h2-4,7,10,12,14H,5-6,8-9,11H2,1H3,(H2,22,24,25,26)	RYFZFQVKNZTNST-UHFFFAOYSA-N	287588	US9567341, Compound C-4::US9968610, Compound C-4::US10420768, Compound C-4::US11752155, Compound C-4A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 11400							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287588	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287588&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938581	378171155							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825449	FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H19F5N6/c20-18(21,15-2-1-12(9-26-15)19(22,23)24)10-30-7-4-13(5-8-30)29-17-14-3-6-25-16(14)27-11-28-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,25,27,28,29)	NTMXMRKJKVFRLP-UHFFFAOYSA-N	287589	US9567341, Compound C-5::US9968610, Compound C-5::US10420768, Compound C-5::US11752155, Compound C-5A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 9500							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287589	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287589&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118559717	378171156							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825451	Cc1cnc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C18H21F2N7/c1-12-8-23-15(9-22-12)18(19,20)10-27-6-3-13(4-7-27)26-17-14-2-5-21-16(14)24-11-25-17/h2,5,8-9,11,13H,3-4,6-7,10H2,1H3,(H2,21,24,25,26)	OLLWXMDGFDGOBR-UHFFFAOYSA-N	287594	US9567341, Compound C-230::US9968610, Compound C-230::US10420768, Compound C-230::US11752155, Compound C-230A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 13800							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287594	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287594&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938588	378171161							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825453	FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H19F5N6/c20-18(21,12-1-2-15(26-9-12)19(22,23)24)10-30-7-4-13(5-8-30)29-17-14-3-6-25-16(14)27-11-28-17/h1-3,6,9,11,13H,4-5,7-8,10H2,(H2,25,27,28,29)	CSLAFKNTMSZKMA-UHFFFAOYSA-N	287596	US9567341, Compound C-127::US9968610, Compound C-127::US10420768, Compound C-127::US11752155, Compound C-127A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6000							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287596	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287596&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938509	378171163							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825455	Cc1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H22F2N6/c1-13-2-3-14(10-23-13)19(20,21)11-27-8-5-15(6-9-27)26-18-16-4-7-22-17(16)24-12-25-18/h2-4,7,10,12,15H,5-6,8-9,11H2,1H3,(H2,22,24,25,26)	WFXULSHSKBXRPA-UHFFFAOYSA-N	287597	US9567341, Compound C-128::US9968610, Compound C-128::US10420768, Compound C-128::US11752155, Compound C-128A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 28000							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287597	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287597&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938568	378171164							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
825457	Fc1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12	InChI=1S/C19H20F3N5/c20-14-3-1-13(2-4-14)19(21,22)11-27-9-6-15(7-10-27)26-18-16-5-8-23-17(16)24-12-25-18/h1-5,8,12,15H,6-7,9-11H2,(H2,23,24,25,26)	ZPTGKQWXVKFGAF-UHFFFAOYSA-N	287604	US9567341, Compound C-175::US9968610, Compound C-175::US10420768, Compound C-175::US11752155, Compound C-175A'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4500							US Patent		10.7270/Q2G1636H		aid1803831	US10420768	Shapiro, G	9/24/2019	8/12/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=287604	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=287604&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			118938512	378171171							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
884138	Cc1ccc(COC(=O)N2CC[C@H](CNc3ncc4cn[nH]c4n3)C(F)(F)C2)cc1 |r|	InChI=1S/C20H22F2N6O2/c1-13-2-4-14(5-3-13)11-30-19(29)28-7-6-16(20(21,22)12-28)10-24-18-23-8-15-9-25-27-17(15)26-18/h2-5,8-9,16H,6-7,10-12H2,1H3,(H2,23,24,25,26,27)	YCJDFVJNRWEUDF-UHFFFAOYSA-N	435146	US10584127, Compound E1-8.2::US11136328, Compound E1-8.2::US11752155, Compound E1-8.2B'	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6800							US Patent		10.7270/Q2Q242NP		aid1804259	US10584127	Shapiro, G	3/10/2020	11/29/2020	Rugen Holdings (Cayman)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=435146	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=435146&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			124121435	438643938							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
887417	C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(F)CO)c1c(F)cc(NC2CN(CCCF)C2)cc1F |r|	InChI=1S/C27H33F4N5O/c1-16-8-20-19(4-5-24-21(20)11-32-34-24)26(36(16)14-27(2,31)15-37)25-22(29)9-17(10-23(25)30)33-18-12-35(13-18)7-3-6-28/h4-5,9-11,16,18,26,33,37H,3,6-8,12-15H2,1-2H3,(H,32,34)	HZEJTMIZKGGUNU-UHFFFAOYSA-N	436237	Preparation of of individual diastereoisomers of 3-((6S,8R)-6-(2,6-difluoro-4-(1-(3-fluoropropyl)azetidin-3-ylamino)phenyl)-8-methyl-8,9-dihydro-3H-pyrazolo[4,3-f]isoquinolin-7(6H)-yl)-2-fluoro-2-methylpropan-1-ol::US10590130, Example 24::US10590130, Example 23::US10961241, Example 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15.0							US Patent		10.7270/Q28S4SX5		aid1804306	US10590130	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	3/17/2020	12/7/2020	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=436237	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=436237&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155295421	439657873							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
887454	COc1cc(OC2CN(CCCF)C2)ccc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1ccc1[nH]ncc21 |r|	InChI=1S/C27H33F3N4O3/c1-17-10-22-20(6-7-24-23(22)12-31-32-24)26(34(17)15-27(29,30)16-35)21-5-4-18(11-25(21)36-2)37-19-13-33(14-19)9-3-8-28/h4-7,11-12,17,19,26,35H,3,8-10,13-16H2,1-2H3,(H,31,32)	FVPASTFQVKDSSX-UHFFFAOYSA-N	436274	US10590130, Example 60::2,2-difluoro-3- ((6S,8R)-6-(4- ((1-(3- fluoropropyl)aze- tidin-3- yl)amino)-2- methoxyphenyl)- 8-methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4.70							US Patent		10.7270/Q28S4SX5		aid1804306	US10590130	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	3/17/2020	12/7/2020	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=436274	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=436274&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155295422	439657909							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
887455	C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)CO)c1ccc(OC2CN(CCCF)C2)cn1 |r|	InChI=1S/C25H29F4N5O2/c1-15-9-19-18(4-6-20-22(19)24(27)32-31-20)23(34(15)13-25(28,29)14-35)21-5-3-16(10-30-21)36-17-11-33(12-17)8-2-7-26/h3-6,10,15,17,23,35H,2,7-9,11-14H2,1H3,(H,31,32)	CJGQDXFVDSVQFT-UHFFFAOYSA-N	436275	US10590130, Example 61::2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(5- ((1-(3- fluoropropyl)aze- tidin-3- yl)amino)pyridin- 2-yl)-8- methyl- 3,6,8,9- tetrahydro-7H- pyrazolo[4,3- f]isoquinolin- 7-yl)propan-1- ol	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 0.880							US Patent		10.7270/Q28S4SX5		aid1804306	US10590130	Barlaam, BC; O Donovan, DH; Hughes, SJ; Moss, TA; Nissink, JW; Scott, JS; Yang, B	3/17/2020	12/7/2020	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=436275	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=436275&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155295423	439657910							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971753	Cc1nc[nH]c1CN1CC[C@@]2(CC1)COC1C(C2)C(C)(C)Oc2cc(Cl)ccc12 |r|	InChI=1S/C23H30ClN3O2/c1-15-19(26-14-25-15)12-27-8-6-23(7-9-27)11-18-21(28-13-23)17-5-4-16(24)10-20(17)29-22(18,2)3/h4-5,10,14,18,21H,6-9,11-13H2,1-3H3,(H,25,26)	PSMLAMNCKIJHKF-UHFFFAOYSA-N	470079	US10807993, Example 19::US10807993, Example 20::Racemate of (4&#8242;aR,10&#8242;bR)-8&#8242;-chloro-5&#8242;,5&#8242;-dimethyl-1-[(4-methyl-1H-imidazol-5-yl)methyl]-4&#8242;a,10&#8242;b-dihydro-2&#8242;H,4&#8242;H,5&#8242;H-spiro[piperidine-4,3&#8242;-pyrano[3,2-c][1]benzopyran] and (4&#8242;aS,10&#8242;bS)-8&#8242;-chloro-5&#8242;,5&#8242;-dimethyl-1-[(4-methyl-1H-imidazol-5-yl)methyl]-4&#8242;a,10&#8242;b-dihydro-2&#8242;H,4&#8242;H,5&#8242;H-spiro[piperidine-4,3&#8242;-pyrano[3,2-c][1]benzopyran]::US10807993, Example 18	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 600							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470079	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470079&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			139526073	441572175							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971756	Cc1nc[nH]c1CN1CC[C@@]2(CC1)COC1C(C2)C(C)(C)Oc2ccc(F)cc12 |r|	InChI=1S/C23H30FN3O2/c1-15-19(26-14-25-15)12-27-8-6-23(7-9-27)11-18-21(28-13-23)17-10-16(24)4-5-20(17)29-22(18,2)3/h4-5,10,14,18,21H,6-9,11-13H2,1-3H3,(H,25,26)	KHQVMLDUIZSQBJ-UHFFFAOYSA-N	470082	US10807993, Example 22::US10807993, Example 23::US10807993, Example 21	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1500							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470082	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470082&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921750	441572176							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971759	Cc1nc[nH]c1CN1CCC2(CC1)COC1C(C2)C(C)(C)Oc2ccc(Cl)cc12	InChI=1S/C23H30ClN3O2/c1-15-19(26-14-25-15)12-27-8-6-23(7-9-27)11-18-21(28-13-23)17-10-16(24)4-5-20(17)29-22(18,2)3/h4-5,10,14,18,21H,6-9,11-13H2,1-3H3,(H,25,26)	LLRZZUHLSAACCU-UHFFFAOYSA-N	470085	US10807993, Example 24	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3800							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470085	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470085&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921751	441572177							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971760	Cc1nc[nH]c1CN1CC[C@@]2(CC1)COC1C(C2)C(C)(C)Oc2ccc(Cl)cc12 |r|	InChI=1S/C23H30ClN3O2/c1-15-19(26-14-25-15)12-27-8-6-23(7-9-27)11-18-21(28-13-23)17-10-16(24)4-5-20(17)29-22(18,2)3/h4-5,10,14,18,21H,6-9,11-13H2,1-3H3,(H,25,26)	LLRZZUHLSAACCU-UHFFFAOYSA-N	470086	US10807993, Example 26::US10807993, Example 25	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 400							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470086	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470086&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921751	441572178							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971762	Cc1nc[nH]c1CN1CCC2(CC1)COC1C(C2)C(C)(C)Oc2c(Cl)cccc12	InChI=1S/C23H30ClN3O2/c1-15-19(26-14-25-15)12-27-9-7-23(8-10-27)11-17-20(28-13-23)16-5-4-6-18(24)21(16)29-22(17,2)3/h4-6,14,17,20H,7-13H2,1-3H3,(H,25,26)	QNOXPCLUMHQZFP-UHFFFAOYSA-N	470088	US10807993, Example 27	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 400							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470088	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470088&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921752	441572179							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971763	CCc1nc(C)c(CN2CCC3(CC2)COC2C(C3)C(C)(C)Oc3ccc(Cl)cc23)[nH]1	InChI=1S/C25H34ClN3O2/c1-5-22-27-16(2)20(28-22)14-29-10-8-25(9-11-29)13-19-23(30-15-25)18-12-17(26)6-7-21(18)31-24(19,3)4/h6-7,12,19,23H,5,8-11,13-15H2,1-4H3,(H,27,28)	MELYYMZGXAYQPV-UHFFFAOYSA-N	470089	US10807993, Example 28	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 700							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470089	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470089&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921753	441572180							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971764	CC1(C)Oc2ccc(Cl)cc2C2OCC3(CCN(Cc4c[nH]cn4)CC3)CC12	InChI=1S/C22H28ClN3O2/c1-21(2)18-10-22(5-7-26(8-6-22)12-16-11-24-14-25-16)13-27-20(18)17-9-15(23)3-4-19(17)28-21/h3-4,9,11,14,18,20H,5-8,10,12-13H2,1-2H3,(H,24,25)	UPGUEMWSDMQHJH-UHFFFAOYSA-N	470090	US10807993, Example 29	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2600							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470090	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470090&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921754	441572181							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971765	Cc1nc(CN2CCC3(CC2)COC2C(C3)C(C)(C)Oc3ccc(Cl)cc23)c[nH]1	InChI=1S/C23H30ClN3O2/c1-15-25-12-17(26-15)13-27-8-6-23(7-9-27)11-19-21(28-14-23)18-10-16(24)4-5-20(18)29-22(19,2)3/h4-5,10,12,19,21H,6-9,11,13-14H2,1-3H3,(H,25,26)	BNIQEUWIYMDMBW-UHFFFAOYSA-N	470091	US10807993, Example 30	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1700							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470091	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470091&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921755	441572182							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971770	CC1(C)Oc2ccc(Cl)cc2C2OCC3(CCN(Cc4ncc[nH]4)CC3)CC12	InChI=1S/C22H28ClN3O2/c1-21(2)17-12-22(5-9-26(10-6-22)13-19-24-7-8-25-19)14-27-20(17)16-11-15(23)3-4-18(16)28-21/h3-4,7-8,11,17,20H,5-6,9-10,12-14H2,1-2H3,(H,24,25)	WKTJEJIWQKDDEA-UHFFFAOYSA-N	470096	US10807993, Example 35	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3500							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470096&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155921760	441572187							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
971796	Cc1nc[nH]c1CN1CCC2(CC1)COC1C(COc3cc(Cl)ccc13)C2	InChI=1S/C21H26ClN3O2/c1-14-18(24-13-23-14)10-25-6-4-21(5-7-25)9-15-11-26-19-8-16(22)2-3-17(19)20(15)27-12-21/h2-3,8,13,15,20H,4-7,9-12H2,1H3,(H,23,24)	ZNXAGHWUHRRZDM-UHFFFAOYSA-N	470122	Racemate of (4&#8242;aS,10&#8242;bR)-8&#8242;-chloro-1-[(4-methyl-1H-imidazol-5-yl)methyl]-4&#8242;a,10&#8242;b-dihydro-2&#8242;H,4&#8242;H,5&#8242;H-spiro[piperidine-4,3&#8242;-pyrano[3,2-c][1]benzopyran] and (4&#8242;aR,10&#8242;bS)-8&#8242;-chloro-1-[(4-methyl-H-imidazol-5-yl)methyl]-4&#8242;a,10&#8242;b-dihydro-2&#8242;H,4&#8242;H,5&#8242;H-spiro[piperidine-4,3&#8242;-pyrano[3,2-c][1]benzopyran]::US10807993, Example 64a::US10807993, Example 64b::US10807993, Example 64	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 400							US Patent		10.7270/Q2SJ1PQB		aid1804954	US10807993	Ban, H; Kamioka, S; Sawayama, Y; Hashizume, M	10/20/2020	6/11/2021	Sumitomo Dainippon Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=470122	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=470122&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			139526273	441572209							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577897	CC(C)c1ccc(C(=O)Nc2ccc(N3CCN(C(=O)C(C)(C)C)CC3)cc2)cc1	InChI=1S/C25H33N3O2/c1-18(2)19-6-8-20(9-7-19)23(29)26-21-10-12-22(13-11-21)27-14-16-28(17-15-27)24(30)25(3,4)5/h6-13,18H,14-17H2,1-5H3,(H,26,29)	UGJNLGUATFWONH-UHFFFAOYSA-N	788823	4-isopropyl-N-(4-(4-pivaloylpiperazin-1-yl)phenyl)benzamide::US20250352542, Compound 1	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788823	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788823&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			8483064	523966467							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577898	Cc1ccc(C(=O)N2CCN(c3ccccc3)CC2)cc1NC(=O)c1ccccc1	InChI=1S/C25H25N3O2/c1-19-12-13-21(18-23(19)26-24(29)20-8-4-2-5-9-20)25(30)28-16-14-27(15-17-28)22-10-6-3-7-11-22/h2-13,18H,14-17H2,1H3,(H,26,29)	NROPHJJPVNDORN-UHFFFAOYSA-N	788825	N-(2-methyl-5-(4-phenylpiperazine-1-carbonyl)phenyl)benzamide::US20250352542, Compound 2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788825	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788825&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			17226314	523966468							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577899	CCOc1ccc(NC(=O)N2CCN(c3cc(N4CCN(C)CC4)nc(C)n3)CC2)cc1	InChI=1S/C23H33N7O2/c1-4-32-20-7-5-19(6-8-20)26-23(31)30-15-13-29(14-16-30)22-17-21(24-18(2)25-22)28-11-9-27(3)10-12-28/h5-8,17H,4,9-16H2,1-3H3,(H,26,31)	NKMYVELIFMSTKG-UHFFFAOYSA-N	788826	N-(4-ethoxyphenyl)-4-(2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl)piperazine-1-carboxamide::US20250352542, Compound 3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788826	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788826&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50747988	523966469							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577900	COc1ccc(NC(=O)N2CCN(c3ccc(-n4nc(C)cc4C)nn3)CC2)cc1Cl	InChI=1S/C21H24ClN7O2/c1-14-12-15(2)29(26-14)20-7-6-19(24-25-20)27-8-10-28(11-9-27)21(30)23-16-4-5-18(31-3)17(22)13-16/h4-7,12-13H,8-11H2,1-3H3,(H,23,30)	CVVXKHHYEWHWLG-UHFFFAOYSA-N	788827	N-(3-chloro-4-methoxyphenyl)-4-(6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl)piperazine-1-carboxamide::US20250352542, Compound 4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 35200							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788827	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788827&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50945197	523966470							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577901	COc1ccc(NC(=O)N2CCN(c3cc(-n4nc(C)cc4C)nc(C)n3)CC2)cc1	InChI=1S/C22H27N7O2/c1-15-13-16(2)29(26-15)21-14-20(23-17(3)24-21)27-9-11-28(12-10-27)22(30)25-18-5-7-19(31-4)8-6-18/h5-8,13-14H,9-12H2,1-4H3,(H,25,30)	XPDAATYKDTZCMZ-UHFFFAOYSA-N	788828	4-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpyrimidin-4-yl)-N-(4-methoxyphenyl)piperazine-1-carboxamide::US20250352542, Compound 5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 45700							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788828	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788828&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50946216	523966471							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577902	COc1ccc(NC(=O)N2CCN(c3cc(-n4nc(C)cc4C)ncn3)CC2)c(C)c1	InChI=1S/C22H27N7O2/c1-15-11-18(31-4)5-6-19(15)25-22(30)28-9-7-27(8-10-28)20-13-21(24-14-23-20)29-17(3)12-16(2)26-29/h5-6,11-14H,7-10H2,1-4H3,(H,25,30)	NKKUPQBZUMDAKA-UHFFFAOYSA-N	788829	4-(6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)piperazine-1-carboxamide::US20250352542, Compound 6	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788829	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788829&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			56699529	523966472							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577903	COc1cc(NC(=O)N2CCN(c3ccc(-n4nc(C)cc4C)nn3)CC2)cc(OC)c1	InChI=1S/C22H27N7O3/c1-15-11-16(2)29(26-15)21-6-5-20(24-25-21)27-7-9-28(10-8-27)22(30)23-17-12-18(31-3)14-19(13-17)32-4/h5-6,11-14H,7-10H2,1-4H3,(H,23,30)	QXURLMUPGVZRLG-UHFFFAOYSA-N	788830	N-(3,5-dimethoxyphenyl)-4-(6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl)piperazine-1-carboxamide::US20250352542, Compound 7	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788830	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788830&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50947849	523966473							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577904	COc1cc(OC)c(NC(=O)N2CCN(c3cc(-n4cnc(C)c4C)ncn3)CC2)cc1Cl	InChI=1S/C22H26ClN7O3/c1-14-15(2)30(13-26-14)21-11-20(24-12-25-21)28-5-7-29(8-6-28)22(31)27-17-9-16(23)18(32-3)10-19(17)33-4/h9-13H,5-8H2,1-4H3,(H,27,31)	UYAMSXGZSFCLSZ-UHFFFAOYSA-N	788862	N-(5-chloro-2,4-dimethoxyphenyl)-4-(6-(4,5-dimethyl-1H-imidazol-1-yl)pyrimidin-4-yl)piperazine-1-carboxamide::US20250352542, Compound 8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788862	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788862&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			56922579	523966476							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577905	Cn1c(=O)n(C)c2cc(NC(=O)c3ccc(N4CCOCC4)cc3)ccc21	InChI=1S/C20H22N4O3/c1-22-17-8-5-15(13-18(17)23(2)20(22)26)21-19(25)14-3-6-16(7-4-14)24-9-11-27-12-10-24/h3-8,13H,9-12H2,1-2H3,(H,21,25)	VMTKURWHGMTKTE-UHFFFAOYSA-N	788863	N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-4-morpholinobenzamide::US20250352542, Compound 13	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30300							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788863	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788863&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			21367948	523966477							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577906	COc1ccc(C=CC(=O)Nc2ccccc2C(=O)O)cc1OC	InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)	NZHGWWWHIYHZNX-UHFFFAOYSA-N	788864	 N-(3,4-Dimethoxycinnamoyl)anthranilic acid::US20250352542, Compound Tranilast	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788864	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788864&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			5527	523966478							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577907	CCCN(C)c1cc(C(F)(F)F)nc(SCCC(=O)NCc2ccco2)n1	InChI=1S/C17H21F3N4O2S/c1-3-7-24(2)14-10-13(17(18,19)20)22-16(23-14)27-9-6-15(25)21-11-12-5-4-8-26-12/h4-5,8,10H,3,6-7,9,11H2,1-2H3,(H,21,25)	LZHSWRWIMQRTOP-UHFFFAOYSA-N	788865	N-(Furan-2-ylmethyl)-3-((4-(methyl(propyl)amino)-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanamide::US20250352542, Compound SET2	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 30000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788865	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788865&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			155541857	523966479							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577908	CCCN(C)c1cc(C(F)(F)F)nc(SC=CC(=O)NCc2ccco2)n1	InChI=1S/C17H19F3N4O2S/c1-3-7-24(2)14-10-13(17(18,19)20)22-16(23-14)27-9-6-15(25)21-11-12-5-4-8-26-12/h4-6,8-10H,3,7,11H2,1-2H3,(H,21,25)	JUYOYIRDSFXXIF-UHFFFAOYSA-N	788866	N-(furan-2-ylmethyl)-3-((4-(methyl(propyl)amino)-6-(trifluoromethyl)pyrimidin-2-yl)thio)propenamide::US20250352542, Compound 15	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 100.0							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788866	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788866&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			170716271	523966480							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577909	O=C(Nc1cccc(NC(=O)N2CCN(c3ccccn3)CC2)c1)c1ccccc1	InChI=1S/C23H23N5O2/c29-22(18-7-2-1-3-8-18)25-19-9-6-10-20(17-19)26-23(30)28-15-13-27(14-16-28)21-11-4-5-12-24-21/h1-12,17H,13-16H2,(H,25,29)(H,26,30)	CQAIZZWAMGHILW-UHFFFAOYSA-N	788867	N-(3-benzamidophenyl)-4-(pyridin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788867	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788867&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162083	523966481							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577910	O=C(Nc1cccc(NC(=O)N2CCN(c3ccccc3)CC2)c1)c1ccccc1	InChI=1S/C24H24N4O2/c29-23(19-8-3-1-4-9-19)25-20-10-7-11-21(18-20)26-24(30)28-16-14-27(15-17-28)22-12-5-2-6-13-22/h1-13,18H,14-17H2,(H,25,29)(H,26,30)	WOUGKSQSAAWPPH-UHFFFAOYSA-N	788868	N-(3-benzamidophenyl)-4-phenylpiperazine-1-carboxamide::US20250352542, Compound GK-ABP4	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788868	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788868&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			52307663	523966482							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577911	O=C(Nc1cccc(NC(=O)N2CCN(c3ncccn3)CC2)c1)c1ccccc1	InChI=1S/C22H22N6O2/c29-20(17-6-2-1-3-7-17)25-18-8-4-9-19(16-18)26-22(30)28-14-12-27(13-15-28)21-23-10-5-11-24-21/h1-11,16H,12-15H2,(H,25,29)(H,26,30)	IYQSSUDIGGWUML-UHFFFAOYSA-N	788869	N-(3-benzamidophenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP5	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788869	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788869&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162149	523966483							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577912	O=C(Nc1cccc(NC(=O)N2CCN(c3cnccn3)CC2)c1)c1ccccc1	InChI=1S/C22H22N6O2/c29-21(17-5-2-1-3-6-17)25-18-7-4-8-19(15-18)26-22(30)28-13-11-27(12-14-28)20-16-23-9-10-24-20/h1-10,15-16H,11-14H2,(H,25,29)(H,26,30)	HLABMDWYOOTISR-UHFFFAOYSA-N	788870	N-(3-benzamidophenyl)-4-(pyrazin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP8	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788870	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788870&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162108	523966484							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577913	CC(C)(C)c1ccc(C(=O)Nc2cccc(NC(=O)N3CCN(c4ncccn4)CC3)c2)cc1	InChI=1S/C26H30N6O2/c1-26(2,3)20-10-8-19(9-11-20)23(33)29-21-6-4-7-22(18-21)30-25(34)32-16-14-31(15-17-32)24-27-12-5-13-28-24/h4-13,18H,14-17H2,1-3H3,(H,29,33)(H,30,34)	OCGDFBAKFRGOCC-UHFFFAOYSA-N	788871	N-(3-(4-(tert-butyl)benzamido)phenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP5-T11	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 7000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788871	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788871&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162038	523966485							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577914	O=C(Nc1cccc(S(=O)(=O)N2CCN(c3ncccn3)CC2)c1)c1ccc(Cl)cc1	InChI=1S/C21H20ClN5O3S/c22-17-7-5-16(6-8-17)20(28)25-18-3-1-4-19(15-18)31(29,30)27-13-11-26(12-14-27)21-23-9-2-10-24-21/h1-10,15H,11-14H2,(H,25,28)	KWDCZOVOQUVTRI-UHFFFAOYSA-N	788872	4-chloro-N-(3-((4-(pyrimidin-2-yl) piperazin-1-yl) sulfonyl)phenyl)benzamide::US20250352542, Compound T10B9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 15900							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788872	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788872&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			170716274	523966486							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577915	O=C(Nc1cccc(NC(=O)N2CCN(c3ncccn3)CC2)c1)c1ccc(Cl)c(Cl)c1	InChI=1S/C22H20Cl2N6O2/c23-18-6-5-15(13-19(18)24)20(31)27-16-3-1-4-17(14-16)28-22(32)30-11-9-29(10-12-30)21-25-7-2-8-26-21/h1-8,13-14H,9-12H2,(H,27,31)(H,28,32)	GMTMRLINECQWEV-UHFFFAOYSA-N	788873	N-(3-(3,4-dichlorobenzamido)phenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP5-T20	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788873	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788873&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			170716304	523966487							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577916	Cc1ccc(C(=O)Nc2cccc(NC(=O)N3CCN(c4ncccn4)CC3)c2)cc1C	InChI=1S/C24H26N6O2/c1-17-7-8-19(15-18(17)2)22(31)27-20-5-3-6-21(16-20)28-24(32)30-13-11-29(12-14-30)23-25-9-4-10-26-23/h3-10,15-16H,11-14H2,1-2H3,(H,27,31)(H,28,32)	WCONZOFERPRYFO-UHFFFAOYSA-N	788874	N-(3-(3,4-dimethylbenzamido)phenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP5-T9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10200							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788874	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788874&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162011	523966488							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577917	CC(C)(C)c1ccc(C(=O)Nc2cccc(S(=O)(=O)N3CCN(c4ncccn4)CC3)c2)cc1	InChI=1S/C25H29N5O3S/c1-25(2,3)20-10-8-19(9-11-20)23(31)28-21-6-4-7-22(18-21)34(32,33)30-16-14-29(15-17-30)24-26-12-5-13-27-24/h4-13,18H,14-17H2,1-3H3,(H,28,31)	IZJGDUCSEMWPDE-UHFFFAOYSA-N	788875	4-(tert-butyl)-N-(3-((4-(pyrimidin-2-yl) piperazin-1-yl) sulfonyl)phenyl)benzamide::US20250352542, Compound T11B9	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788875	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788875&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162090	523966489							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577918	COc1ccc(C(=O)Nc2cccc(NC(=O)N3CCN(c4ncccn4)CC3)c2)cc1	InChI=1S/C23H24N6O3/c1-32-20-8-6-17(7-9-20)21(30)26-18-4-2-5-19(16-18)27-23(31)29-14-12-28(13-15-29)22-24-10-3-11-25-22/h2-11,16H,12-15H2,1H3,(H,26,30)(H,27,31)	SDHSAGJJQPNWQR-UHFFFAOYSA-N	788876	N-(3-(4-methoxybenzamido)phenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide::US20250352542, Compound GK-ABP5-T19	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>100000							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788876	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788876&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			174162055	523966490							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
1577919	O=C(Nc1cccc(NC(=O)N2CCC3(CCN(c4ncccn4)C3)C2)c1)c1ccc(Cl)cc1	InChI=1S/C25H25ClN6O2/c26-19-7-5-18(6-8-19)22(33)29-20-3-1-4-21(15-20)30-24(34)32-14-10-25(17-32)9-13-31(16-25)23-27-11-2-12-28-23/h1-8,11-12,15H,9-10,13-14,16-17H2,(H,29,33)(H,30,34)	MOAQQYHFKWZXAQ-UHFFFAOYSA-N	788877	N-(3-(4-chlorobenzamido)phenyl)-7-(pyrimidin-2-yl)-2,7-diazaspiro[4.4]nonane-2-carboxamide::US20250352542, Compound T10C3	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1600							US Patent		10.7270/Q2Z324FK			US20250352542	KEREN, G; ENTIN-MEER, M; HAIMOV, E; REDKO, B; ENGEL, H; YEHESKEL, A; CHALIK, M; PICHINUK, E; RAVEH, A; GAZIT, E; GILEAD, S; BUZHANSKI, L; SHANKAR, S	11/20/2025	3/10/2026	Ichilov Tech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=788877	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=788877&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			170716277	523966491							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50021098	[H][C@@]1(C[C@@]2([H])C[C@]3([H])C[C@@]([H])(C1)N2CC3=O)OC(=O)c1c[nH]c2ccccc12 |r,TLB:11:9:14.13:3.5,2:3:9.8:14.13,16:1:12:8.6.5,THB:14:6:12:11.1.2,15:14:9.8:3.5|	InChI=1S/C19H20N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,20H,5-8,10H2	UKTAZPQNNNJVKR-UHFFFAOYSA-N	50451546	Anzemet Cinv::Dolasetron	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12023							ChEMBL	10.1016/s0960-894x(03)00492-x	10.7270/Q2QZ2BGZ	12873512			Keseru, GM	7/22/2003	10/8/2012	Gedeon Richter	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451546&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			3033818	225145402					C07866		1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50301839	Cl.C1CCN(C1)C12CC(C(CNC1)C(C2)c1ccccc1)c1ccccc1 |THB:21:8:13.14:12.11.10,15:13:8.7:12.11.10,(6.25,-1.11,;3.69,2.29,;2.84,3.58,;1.35,3.17,;1.3,1.64,;2.73,1.09,;.02,.79,;,2.34,;-.7,1.05,;-.62,-.75,;.87,-.68,;1.96,-1.45,;1.56,.11,;-1.7,-1.51,;-1.36,.04,;-2.55,-2.79,;-3.98,-3.3,;-4.25,-4.82,;-3.08,-5.81,;-1.63,-5.29,;-1.35,-3.78,;-2.2,1.4,;-2.35,2.95,;-3.75,3.6,;-5,2.71,;-4.86,1.17,;-3.46,.53,)|	InChI=1S/C24H30N2.ClH/c1-3-9-19(10-4-1)21-15-24(26-13-7-8-14-26)16-22(23(21)17-25-18-24)20-11-5-2-6-12-20;/h1-6,9-12,21-23,25H,7-8,13-18H2;1H	FRIFQMDWNMUATD-UHFFFAOYSA-N	50065629	CHEMBL3401424	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2630							ChEMBL	10.1016/j.bmcl.2015.02.044	10.7270/Q28G8ND6	25746816			Seebacher, W; Wolkinger, V; Faist, J; Kaiser, M; Brun, R; Saf, R; Bucar, F; Gröblacher, B; Brantner, A; Merino, V; Kalia, Y; Scapozza, L; Perozzo, R; Weis, R	3/24/2015	4/9/2016	Karl-Franzens-University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065629	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065629&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			51349244	313071455		CHEMBL3401424					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50334468	FC(F)(F)c1cc(COC2CCC3CCC2(N3)c2ccccc2)cc(c1)C(F)(F)F |THB:8:9:16:13.14|	InChI=1S/C22H21F6NO/c23-21(24,25)16-10-14(11-17(12-16)22(26,27)28)13-30-19-7-6-18-8-9-20(19,29-18)15-4-2-1-3-5-15/h1-5,10-12,18-19,29H,6-9,13H2	QOOGOLVYWAKPMZ-UHFFFAOYSA-N	50180546	2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL380351	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 300								ChEMBL	10.1016/j.bmcl.2005.12.069	10.7270/Q28W3CWD	16413782			Huscroft, IT; Carlson, EJ; Chicchi, GG; Kurtz, MM; London, C; Raubo, P; Wheeldon, A; Kulagowski, JJ	2/27/2006	11/10/2009	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180546	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180546&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			22724580	104065624		CHEMBL380351					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50334470	C[C@@H](OC1CCC2NC1(CC2S(=O)(=O)c1ccccc1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |TLB:2:3:7:10.9,THB:11:10:7:4.5.3|	InChI=1S/C29H27F6NO3S/c1-18(19-14-21(28(30,31)32)16-22(15-19)29(33,34)35)39-26-13-12-24-25(40(37,38)23-10-6-3-7-11-23)17-27(26,36-24)20-8-4-2-5-9-20/h2-11,14-16,18,24-26,36H,12-13,17H2,1H3	ZSJXCCAWETXSOR-UHFFFAOYSA-N	50180548	2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-phenyl-6-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL381555	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1930								ChEMBL	10.1016/j.bmcl.2005.12.069	10.7270/Q28W3CWD	16413782			Huscroft, IT; Carlson, EJ; Chicchi, GG; Kurtz, MM; London, C; Raubo, P; Wheeldon, A; Kulagowski, JJ	2/27/2006	11/10/2009	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180548	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180548&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44410191	104065626		CHEMBL381555					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50334478	FC(F)(F)c1cc(COC2CCC3NC2(CC3S(=O)(=O)c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F |TLB:8:9:13:16.15,THB:17:16:13:10.11.9|	InChI=1S/C28H25F6NO3S/c29-27(30,31)20-13-18(14-21(15-20)28(32,33)34)17-38-25-12-11-23-24(39(36,37)22-9-5-2-6-10-22)16-26(25,35-23)19-7-3-1-4-8-19/h1-10,13-15,23-25,35H,11-12,16-17H2	MXKZKTBJVYCBDH-UHFFFAOYSA-N	50180554	2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-6-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL379152	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 1300								ChEMBL	10.1016/j.bmcl.2005.12.069	10.7270/Q28W3CWD	16413782			Huscroft, IT; Carlson, EJ; Chicchi, GG; Kurtz, MM; London, C; Raubo, P; Wheeldon, A; Kulagowski, JJ	2/27/2006	11/10/2009	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180554	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180554&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44410155	104065632		CHEMBL379152					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50334479	C[C@@H](OC1CCC2NC1(CC2(F)c1nnn(C)n1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |TLB:11:10:7:4.5.3,2:3:7:10.9,THB:12:10:7:4.5.3|	InChI=1S/C25H24F7N5O/c1-14(15-10-17(24(27,28)29)12-18(11-15)25(30,31)32)38-20-9-8-19-22(26,21-34-36-37(2)35-21)13-23(20,33-19)16-6-4-3-5-7-16/h3-7,10-12,14,19-20,33H,8-9,13H2,1-2H3	VNEJEACQXCJUFD-UHFFFAOYSA-N	50180555	2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-fluoro-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL207794	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	>5000								ChEMBL	10.1016/j.bmcl.2005.12.069	10.7270/Q28W3CWD	16413782			Huscroft, IT; Carlson, EJ; Chicchi, GG; Kurtz, MM; London, C; Raubo, P; Wheeldon, A; Kulagowski, JJ	2/27/2006	11/10/2009	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180555	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180555&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			44410317	104065633		CHEMBL207794					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50404533	[H][C@]12C[C@](CCN(C)CCCc3nc4cccc(OC)c4[nH]3)(OC(=O)C(C)C)[C@]([H])(CCC1)c1ccccc21 |r,TLB:34:33:3.2:30.32.31,22:3:38.33:30.32.31,THB:37:38:3.2:30.32.31,4:3:38.33:30.32.31|	InChI=1S/C31H41N3O3/c1-21(2)30(35)37-31(20-22-10-7-13-25(31)24-12-6-5-11-23(22)24)17-19-34(3)18-9-16-28-32-26-14-8-15-27(36-4)29(26)33-28/h5-6,8,11-12,14-15,21-22,25H,7,9-10,13,16-20H2,1-4H3,(H,32,33)	OZBPEBNJOSXIBE-UHFFFAOYSA-N	50116521	CHEMBL3609819	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		<400							ChEMBL	10.1016/j.bmcl.2015.07.038	10.7270/Q24M96BF	26231163			Renneberg, D; Hubler, F; Rey, M; Hess, P; Delahaye, S; Gatfield, J; Iglarz, M; Hilpert, K	8/17/2015	11/27/2016	Actelion Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116521	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116521&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			46203897	319494287		CHEMBL3609819					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50459693	CC(CCNCC12CC3CC(CC(C3)C1)C2)Nc1ccnc2cc(Cl)ccc12 |TLB:13:8:15:12.14.11,13:12:15:7.8.9,THB:11:10:7:13.12.14,11:12:7:15.9.10|	InChI=1S/C24H32ClN3/c1-16(28-22-5-7-27-23-11-20(25)2-3-21(22)23)4-6-26-15-24-12-17-8-18(13-24)10-19(9-17)14-24/h2-3,5,7,11,16-19,26H,4,6,8-10,12-15H2,1H3,(H,27,28)	YZLGJCZNYFJCLX-UHFFFAOYSA-N	50142038	CHEMBL3758349	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>5000							ChEMBL	10.1021/acs.jmedchem.5b01374	10.7270/Q2CR5W7D	26640981			Terzic, N; Konstantinovic, J; Tot, M; Burojevic, J; Djurkovic-Djakovic, O; Srbljanovic, J; Štajner, T; Verbic, T; Zlatovic, M; Machado, M; Albuquerque, IS; Prudêncio, M; Sciotti, RJ; Pecic, S; D'Alessandro, S; Taramelli, D; Šolaja, BA	1/14/2016	6/6/2017	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142038	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142038&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			127029260	336952707		CHEMBL3758349					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50459694	CC(CCNCC12CC3CC(CC(C3)C1)C2)Nc1c(F)cnc2cc(Cl)ccc12 |TLB:13:8:15:12.14.11,13:12:15:7.8.9,THB:11:10:7:13.12.14,11:12:7:15.9.10|	InChI=1S/C24H31ClFN3/c1-15(29-23-20-3-2-19(25)9-22(20)28-13-21(23)26)4-5-27-14-24-10-16-6-17(11-24)8-18(7-16)12-24/h2-3,9,13,15-18,27H,4-8,10-12,14H2,1H3,(H,28,29)	KIHGALWXDRTVFU-UHFFFAOYSA-N	50142039	CHEMBL3758840	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>5000							ChEMBL	10.1021/acs.jmedchem.5b01374	10.7270/Q2CR5W7D	26640981			Terzic, N; Konstantinovic, J; Tot, M; Burojevic, J; Djurkovic-Djakovic, O; Srbljanovic, J; Štajner, T; Verbic, T; Zlatovic, M; Machado, M; Albuquerque, IS; Prudêncio, M; Sciotti, RJ; Pecic, S; D'Alessandro, S; Taramelli, D; Šolaja, BA	1/14/2016	6/6/2017	University of Belgrade	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142039	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142039&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			127029262	336952708		CHEMBL3758840					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50461268	COc1ccc2-c3c(C4CCCCC4)c4ccc(cc4n3C[C@]3(C[C@H]3c2c1)C(=O)N1C2CCC1CN(C)C2)C(=O)NS(=O)(=O)N(C)C |r,THB:36:35:29:31.32|	InChI=1S/C36H45N5O5S/c1-38(2)47(44,45)37-34(42)23-10-14-28-31(16-23)40-21-36(35(43)41-24-11-12-25(41)20-39(3)19-24)18-30(36)29-17-26(46-4)13-15-27(29)33(40)32(28)22-8-6-5-7-9-22/h10,13-17,22,24-25,30H,5-9,11-12,18-21H2,1-4H3,(H,37,42)	ZTTKEBYSXUCBSE-UHFFFAOYSA-N	50448498	BMS-791325::Beclabuvir	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 26000							ChEMBL	10.1016/j.bmcl.2015.12.058	10.7270/Q2ZG6V33	26747393			Hewawasam, P; Tu, Y; Gao, M; Hanumegowda, U; Knipe, J; Lemm, JA; Parker, DD; Rigat, KL; Roberts, SB; Meanwell, NA; Kadow, JF	1/25/2016	6/8/2017	Bristol-Myers Squibb Pharmaceutical Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50448498	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50448498&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			49773361	194946394							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50478724	C1CC(CCO1)C1NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)C12CC3CC(CC(C3)C1)C2 |TLB:31:26:33:30.32.29,31:30:33:25.26.27,THB:29:28:25:31.30.32,29:30:25:33.27.28|	InChI=1S/C29H36N4O/c1-2-4-23-21(3-1)22-12-24(32-26(27(22)31-23)20-5-7-34-8-6-20)28-30-16-25(33-28)29-13-17-9-18(14-29)11-19(10-17)15-29/h1-4,16-20,24,26,31-32H,5-15H2,(H,30,33)	GUAHVUWKWMHTTN-UHFFFAOYSA-N	50154534	CHEMBL3775851	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 506							ChEMBL	10.1016/j.bmcl.2016.02.022	10.7270/Q2ZG6V4J	26898814			He, S; Dobbelaar, PH; Guo, L; Ye, Z; Liu, J; Jian, T; Truong, Q; Shah, SK; Du, W; Qi, H; Bakshi, RK; Hong, Q; Dellureficio, JD; Sherer, E; Pasternak, A; Feng, Z; Reibarkh, M; Lin, M; Samuel, K; Reddy, VB; Mitelman, S; Tong, SX; Chicchi, GG; Tsao, KL; Trusca, D; Wu, M; Shao, Q; Trujillo, ME; Fernandez, G; Nelson, D; Bunting, P; Kerr, J; Fitzgerald, P; Morissette, P; Volksdorf, S; Eiermann, GJ; Li, C; Zhang, BB; Howard, AD; Zhou, YP; Nargund, RP; Hagmann, WK	3/1/2016	7/7/2017	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154534	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154534&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			127032342	104042198		CHEMBL3775851					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50516481	OC12CC3CC(C1)CC(C3)(C2)NC(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1 |TLB:11:8:4:2.1.6,9:8:4.3.2:6,0:1:4:7.9.8,THB:9:3:6:7.8.10,10:8:4:2.1.6,10:1:4:7.9.8|	InChI=1S/C28H35F3N4O2/c29-28(30,31)22-1-3-24(4-2-22)35-10-5-19(17-35)16-34-8-6-23(7-9-34)32-25(36)33-26-12-20-11-21(13-26)15-27(37,14-20)18-26/h1-5,10,17,20-21,23,37H,6-9,11-16,18H2,(H2,32,33,36)	JRAIDSQDLQLLFW-UHFFFAOYSA-N	50297618	1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-ylmethyl]-piperidin-4-yl}-urea::CHEMBL552144	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>31600							ChEMBL	10.1016/j.bmcl.2009.05.066	10.7270/Q24Q7V1J	19500982			Berglund, S; Egner, BJ; Graden, H; Graden, J; Morgan, DG; Inghardt, T; Giordanetto, F	7/14/2009	8/27/2010	Astrazeneca R & D M&#163;Lndal	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297618	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297618&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			45272024	104139149		CHEMBL552144					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50607235	Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCS(=O)CC1)c1cccc(F)c1 |r,THB:18:17:10.11.16:13.14|	InChI=1S/C30H37FN4O2S/c1-20-32-28-7-2-3-8-29(28)35(20)26-18-24-9-10-25(19-26)34(24)14-11-27(22-5-4-6-23(31)17-22)33-30(36)21-12-15-38(37)16-13-21/h2-8,17,21,24-27H,9-16,18-19H2,1H3,(H,33,36)	KCWZRQVPIWKDIC-UHFFFAOYSA-N	50330094	1-Oxo-tetrahydro-thiopyran-4-carboxylic acid{1-(3-fluoro-phenyl)-3-[(1S,5R)-3-(2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propyl}-amide::CHEMBL1271940	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2010.09.089	10.7270/Q23N23M5	20934332			Pryde, DC; Jones, R; Middleton, DS; Laverty, BJ; Fenwick, DR; Mason, HJ; Corless, M; Smith, NN	10/19/2010	6/13/2011	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330094	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330094&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			52941880	123109209		CHEMBL1271940					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50607236	Cc1nc2ccc(F)cc2n1C1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCS(=O)(=O)CC1)c1cccc(F)c1 |r,THB:19:18:11.12.17:14.15|	InChI=1S/C30H36F2N4O3S/c1-19-33-28-8-5-23(32)16-29(28)36(19)26-17-24-6-7-25(18-26)35(24)12-9-27(21-3-2-4-22(31)15-21)34-30(37)20-10-13-40(38,39)14-11-20/h2-5,8,15-16,20,24-27H,6-7,9-14,17-18H2,1H3,(H,34,37)	MKBMJDPTELZANI-UHFFFAOYSA-N	50330095	1,1-Dioxo-hexahydro-1lambda*6*-thiopyran-4-carboxylic acid [3-[(1S,5R)-3-(6-fluoro-2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-(3-fluoro-phenyl)-propyl]-amide::CHEMBL1269335	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2010.09.089	10.7270/Q23N23M5	20934332			Pryde, DC; Jones, R; Middleton, DS; Laverty, BJ; Fenwick, DR; Mason, HJ; Corless, M; Smith, NN	10/19/2010	6/13/2011	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330095	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330095&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			52943069	123109210		CHEMBL1269335					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50607237	Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCSCC1)c1cccc(F)c1 |r,THB:18:17:10.11.16:13.14|	InChI=1S/C30H37FN4OS/c1-20-32-28-7-2-3-8-29(28)35(20)26-18-24-9-10-25(19-26)34(24)14-11-27(22-5-4-6-23(31)17-22)33-30(36)21-12-15-37-16-13-21/h2-8,17,21,24-27H,9-16,18-19H2,1H3,(H,33,36)	VFCFLBJGQGUVFG-UHFFFAOYSA-N	50330096	N-((1S)-1-(3-fluorophenyl)-3-((1R,5S)-3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)propyl)tetrahydro-2H-thiopyran-4-carboxamide::CHEMBL1271606	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 740							ChEMBL	10.1016/j.bmcl.2010.09.089	10.7270/Q23N23M5	20934332			Pryde, DC; Jones, R; Middleton, DS; Laverty, BJ; Fenwick, DR; Mason, HJ; Corless, M; Smith, NN	10/19/2010	6/13/2011	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330096	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330096&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			52942126	123109211		CHEMBL1271606					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50755441	[H][C@@]12CC[C@]([H])([C@H]1NC(=O)c1ccc(cc1Cl)-n1cnc(C)n1)N(C2)c1ncc(Cl)c2cnoc12 |r,TLB:7:6:23.24:2.3,THB:25:23:6:2.3|	InChI=1S/C22H19Cl2N7O2/c1-11-26-10-31(29-11)13-3-4-14(16(23)6-13)22(32)28-19-12-2-5-18(19)30(9-12)21-20-15(7-27-33-20)17(24)8-25-21/h3-4,6-8,10,12,18-19H,2,5,9H2,1H3,(H,28,32)	PQCRELQHENQSGP-UHFFFAOYSA-N	50240469	CHEMBL4096341	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2017.03.002	10.7270/Q28054RH	28408226			Sakurada, I; Endo, T; Hikita, K; Hirabayashi, T; Hosaka, Y; Kato, Y; Maeda, Y; Matsumoto, S; Mizuno, T; Nagasue, H; Nishimura, T; Shimada, S; Shinozaki, M; Taguchi, K; Takeuchi, K; Yokoyama, T; Hruza, A; Reichert, P; Zhang, T; Wood, HB; Nakao, K; Furusako, S	6/1/2017	10/3/2019	Mochida Pharmaceutical	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240469	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240469&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			128254	104098310		CHEMBL4096341					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50848727	NC(=O)CNC[C@H]1CC[C@]2(CC1)OO[C@@]1(O2)C2CC3CC(C2)CC1C3 |w:18.19,20.22,16.18,23.25,wU:14.14,9.12,6.5,TLB:21:16:19.20.22:24,THB:15:14:19.20.22:24,13:14:19.20.22:24,14:16:19:22.23.24,14:23:19:17.21.16,TEB:21:20:24:17.16.14,22:23:17:19.20.21,(25.77,-11.15,;27.09,-10.36,;28.44,-11.11,;27.07,-8.82,;25.73,-8.06,;25.71,-6.52,;24.36,-5.77,;23.04,-6.56,;21.7,-5.81,;21.68,-4.27,;23,-3.47,;24.34,-4.23,;21.49,-2.73,;19.98,-2.44,;19.23,-3.79,;20.28,-4.92,;18.12,-4.85,;16.9,-4.09,;16.32,-2.81,;14.58,-2.84,;15.92,-3.62,;16.5,-5.02,;17.05,-2.51,;18.66,-2.39,;17.38,-1.76,)|	InChI=1S/C19H30N2O4/c20-17(22)11-21-10-12-1-3-18(4-2-12)23-19(25-24-18)15-6-13-5-14(8-15)9-16(19)7-13/h12-16,21H,1-11H2,(H2,20,22)	RTISLUNVDWEWQD-UHFFFAOYSA-N	50201425	2-({dispiro[adamantane-2,2'-[1,3,5]trioxolane-4',1''-cyclohexane]-4''-ylmethyl}amino)acetamide::CHEMBL233781	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2700							ChEMBL	10.1016/j.bmcl.2006.12.007	10.7270/Q2N017B8	17189686			Tang, Y; Dong, Y; Wittlin, S; Charman, SA; Chollet, J; Chiu, FC; Charman, WN; Matile, H; Urwyler, H; Dorn, A; Bajpai, S; Wang, X; Padmanilayam, M; Karle, JM; Brun, R; Vennerstrom, JL	2/19/2007	12/11/2012	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201425	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201425&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			10405623	104081284		CHEMBL233781					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50848728	NC[C@H]1CC[C@]2(CC1)OO[C@@]1(O2)C2CC3CC(C2)CC1C3 |w:14.15,16.18,12.14,19.21,wU:10.10,5.8,2.1,TLB:17:12:15.16.18:20,THB:11:10:15.16.18:20,9:10:15.16.18:20,10:12:15:18.19.20,10:19:15:13.17.12,TEB:17:16:20:13.12.10,18:19:13:15.16.17,(13.45,-13.89,;13.42,-12.35,;12.07,-11.6,;10.75,-12.4,;9.41,-11.66,;9.37,-10.12,;10.69,-9.32,;12.04,-10.06,;9.17,-8.58,;7.66,-8.3,;6.92,-9.66,;7.98,-10.78,;5.82,-10.73,;4.59,-9.98,;4.01,-8.7,;2.26,-8.74,;3.61,-9.51,;4.2,-10.91,;4.73,-8.39,;6.34,-8.26,;5.06,-7.64,)|	InChI=1S/C17H27NO3/c18-10-11-1-3-16(4-2-11)19-17(21-20-16)14-6-12-5-13(8-14)9-15(17)7-12/h11-15H,1-10,18H2	WAFZISBSKUIZLT-UHFFFAOYSA-N	50201426	dispiro[adamantane-2,2'-[1,3,5]trioxolane-4',1''-cyclohexane]-4''-ylmethanamine; methanesulfonate	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1800							ChEMBL	10.1016/j.bmcl.2006.12.007	10.7270/Q2N017B8	17189686			Tang, Y; Dong, Y; Wittlin, S; Charman, SA; Chollet, J; Chiu, FC; Charman, WN; Matile, H; Urwyler, H; Dorn, A; Bajpai, S; Wang, X; Padmanilayam, M; Karle, JM; Brun, R; Vennerstrom, JL	2/19/2007	12/11/2012	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201426	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201426&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			9890681	104081285							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919688	CC(=O)N[C@@H](CCN1[C@H]2CC[C@@H]1C[C@@H](C2)n1c(C)nc2CN(CCc12)C(=O)C(C)(C)C)c1cccc(F)c1 |r,THB:6:7:14.13.12:9.10|	InChI=1S/C30H42FN5O2/c1-19-32-27-18-34(29(38)30(3,4)5)13-12-28(27)36(19)25-16-23-9-10-24(17-25)35(23)14-11-26(33-20(2)37)21-7-6-8-22(31)15-21/h6-8,15,23-26H,9-14,16-18H2,1-5H3,(H,33,37)	OALXFTNKIGJWPY-UHFFFAOYSA-N	50334963	endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-pivaloyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)propyl)acetamide::CHEMBL1649933	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334963	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334963&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50992722	125085065		CHEMBL1649933					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919689	CC(C)C(=O)N1CCc2c(C1)nc(C)n2[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(C)=O)c1cccc(F)c1 |r,THB:23:22:16.15.21:18.19|	InChI=1S/C29H40FN5O2/c1-18(2)29(37)33-12-11-28-27(17-33)31-19(3)35(28)25-15-23-8-9-24(16-25)34(23)13-10-26(32-20(4)36)21-6-5-7-22(30)14-21/h5-7,14,18,23-26H,8-13,15-17H2,1-4H3,(H,32,36)	QETUKYDWZIRTEI-UHFFFAOYSA-N	50334964	N-{(1S)-3-[3-endo-(5-Isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-(3-fluorophenyl)propyl}acetamide::CHEMBL1649931	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 12000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334964	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334964&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			53316710	125085066		CHEMBL1649931					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919690	CCCC(=O)N1CCc2c(C1)nc(C)n2[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(C)=O)c1cccc(F)c1 |r,THB:23:22:16.15.21:18.19|	InChI=1S/C29H40FN5O2/c1-4-6-29(37)33-13-12-28-27(18-33)31-19(2)35(28)25-16-23-9-10-24(17-25)34(23)14-11-26(32-20(3)36)21-7-5-8-22(30)15-21/h5,7-8,15,23-26H,4,6,9-14,16-18H2,1-3H3,(H,32,36)	GROFPPUYVVUDRM-UHFFFAOYSA-N	50334965	endo-N-((S)-3-(3-(5-butyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-(3-fluorophenyl)propyl)acetamide::CHEMBL1649932	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334965	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334965&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50992721	125085067		CHEMBL1649932					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919691	CCC(=O)N1CCc2c(C1)nc(C)n2[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(C)=O)c1cccc(F)c1 |r,THB:22:21:15.14.20:17.18|	InChI=1S/C28H38FN5O2/c1-4-28(36)32-12-11-27-26(17-32)30-18(2)34(27)24-15-22-8-9-23(16-24)33(22)13-10-25(31-19(3)35)20-6-5-7-21(29)14-20/h5-7,14,22-25H,4,8-13,15-17H2,1-3H3,(H,31,35)	WXXISHFEQSMQJE-UHFFFAOYSA-N	50334966	endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-propionyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)propyl)acetamide::CHEMBL1649930	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334966	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334966&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11785237	125085068		CHEMBL1649930					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919692	CC(=O)N[C@@H](CCN1[C@H]2CC[C@@H]1C[C@@H](C2)n1c(C)nc2CN(CCc12)C(C)=O)c1cccc(F)c1 |r,THB:6:7:14.13.12:9.10|	InChI=1S/C27H36FN5O2/c1-17-29-26-16-31(19(3)35)11-10-27(26)33(17)24-14-22-7-8-23(15-24)32(22)12-9-25(30-18(2)34)20-5-4-6-21(28)13-20/h4-6,13,22-25H,7-12,14-16H2,1-3H3,(H,30,34)	DVTXANDPYZUJRD-UHFFFAOYSA-N	50334967	endo-N-((S)-3-(3-(5-acetyl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-(3-fluorophenyl)propyl)acetamide::CHEMBL1649911	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334967	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334967&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50992720	125085069		CHEMBL1649911					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919693	COC(=O)N1CCc2c(C1)nc(C)n2[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(C)=O)c1cccc(F)c1 |r,THB:22:21:15.14.20:17.18|	InChI=1S/C27H36FN5O3/c1-17-29-25-16-31(27(35)36-3)11-10-26(25)33(17)23-14-21-7-8-22(15-23)32(21)12-9-24(30-18(2)34)19-5-4-6-20(28)13-19/h4-6,13,21-24H,7-12,14-16H2,1-3H3,(H,30,34)	RQXFDQXROYNMQI-UHFFFAOYSA-N	50334968	Methyl 1-endo-{8-[(3S)-3-(Acetamido)-3-(3-fluorophenyl)propyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-methyl-4,5,6,7-tetrahydro-1H-imidazo-[4,5-c]pyridine-5-carboxylate::CHEMBL1649910	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334968	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334968&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50992499	125085070		CHEMBL1649910					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919694	CC(=O)N[C@@H](CCN1[C@H]2CC[C@@H]1C[C@@H](C2)n1c(C)nc2CN(CCc12)c1ccncn1)c1cccc(F)c1 |r,THB:6:7:14.13.12:9.10|	InChI=1S/C29H36FN7O/c1-19-33-27-17-35(29-8-11-31-18-32-29)12-10-28(27)37(19)25-15-23-6-7-24(16-25)36(23)13-9-26(34-20(2)38)21-4-3-5-22(30)14-21/h3-5,8,11,14,18,23-26H,6-7,9-10,12-13,15-17H2,1-2H3,(H,34,38)	QWFGTDDNQVGRKP-UHFFFAOYSA-N	50334969	endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-(pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)propyl)acetamide::CHEMBL1649928	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 10							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334969	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334969&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50992643	125085071		CHEMBL1649928					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919695	CC(=O)N[C@@H](CCN1[C@H]2CC[C@@H]1C[C@@H](C2)n1c(C)nc2CN(CCc12)c1cnccn1)c1cccc(F)c1 |r,THB:6:7:14.13.12:9.10|	InChI=1S/C29H36FN7O/c1-19-33-27-18-35(29-17-31-10-11-32-29)12-9-28(27)37(19)25-15-23-6-7-24(16-25)36(23)13-8-26(34-20(2)38)21-4-3-5-22(30)14-21/h3-5,10-11,14,17,23-26H,6-9,12-13,15-16,18H2,1-2H3,(H,34,38)	WOXHINDXMMSUOT-UHFFFAOYSA-N	50334970	endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-(pyrazin-2-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)propyl)acetamide::CHEMBL1649929	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1000							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334970	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334970&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			50992719	125085072		CHEMBL1649929					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919696	CC(=O)N[C@@H](CCN1[C@H]2CC[C@@H]1C[C@@H](C2)n1c(C)nc2ccccc12)c1ccccc1 |r,THB:6:7:14.13.12:9.10|	InChI=1S/C26H32N4O/c1-18-27-25-10-6-7-11-26(25)30(18)23-16-21-12-13-22(17-23)29(21)15-14-24(28-19(2)31)20-8-4-3-5-9-20/h3-11,21-24H,12-17H2,1-2H3,(H,28,31)	QVXHHQGBOHNEEA-UHFFFAOYSA-N	50334971	endo-N-((S)-3-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)acetamide::CHEMBL1649913	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 1500							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334971	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334971&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			53325983	125085073		CHEMBL1649913					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50919697	CC(C)c1nc(C)nn1[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1 |r,THB:17:16:10.9.15:12.13|	InChI=1S/C29H41F2N5O/c1-19(2)27-32-20(3)34-36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)33-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,33,37)	PTUIAFZYMVYAII-UHFFFAOYSA-N	50334972	endo-4,4-difluoro-N-((S)-3-(3-(5-isopropyl-3-methyl-1H-1,2,4-triazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)cyclohexanecarboxamide::CHEMBL1649912	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4230							ChEMBL	10.1021/jm100978n	10.7270/Q2RV0PNV	21128663			Galan, SR; Jones, RM; Smith, NN; Dorr, PK; Westby, M; Perruccio, F; Rodrigues, D	1/13/2011	1/4/2013	Pfizer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334972	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334972&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			49768863	125085074		CHEMBL1649912					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50930065	COc1cc(ccc1-n1cnc(C)c1)-c1cn(CC(=O)NC2C3CC4CC(C3)CC2C4)nn1 |TLB:30:29:27:23.24.25,20:21:23.30.24:28.26.27,THB:30:24:21.29.28:27,25:24:21:28.26.27,25:26:21:23.30.24,20:21:27:23.24.25,(8.05,-8.55,;8.05,-10.09,;9.39,-10.86,;10.71,-10.09,;12.05,-10.85,;12.05,-12.4,;10.72,-13.17,;9.38,-12.4,;8.06,-13.17,;6.65,-12.54,;5.62,-13.69,;6.39,-15.02,;5.76,-16.43,;7.9,-14.7,;13.38,-10.08,;14.79,-10.7,;15.81,-9.55,;17.35,-9.58,;18.14,-8.26,;17.4,-6.91,;19.68,-8.28,;20.43,-9.63,;21.63,-8.35,;22.96,-8.84,;24.35,-8.49,;24.36,-6.96,;22.97,-6.39,;21.62,-6.86,;21.93,-7.62,;21.93,-9.21,;23.34,-9.77,;15.04,-8.22,;13.53,-8.55,)|	InChI=1S/C25H30N6O2/c1-15-11-30(14-26-15)22-4-3-18(10-23(22)33-2)21-12-31(29-28-21)13-24(32)27-25-19-6-16-5-17(8-19)9-20(25)7-16/h3-4,10-12,14,16-17,19-20,25H,5-9,13H2,1-2H3,(H,27,32)	FRTLIBZJRQYHKR-UHFFFAOYSA-N	50381444	CHEMBL2017412	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 4030							ChEMBL	10.1016/j.bmcl.2012.03.054	10.7270/Q24Q7W0H	22497762			Fischer, C; Zultanski, SL; Zhou, H; Methot, JL; Shah, S; Nuthall, H; Hughes, BL; Smotrov, N; Hill, A; Szewczak, AA; Moxham, CM; Bays, N; Middleton, RE; Munoz, B; Shearman, MS	4/20/2012	2/7/2013	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381444	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381444&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			59472546	160860527		CHEMBL2017412					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50930066	COc1cc(ccc1-n1cnc(C)c1)-c1cn(CC(=O)N(Cc2ccc(F)cc2)C2C3CC4CC(C3)CC2C4)nn1 |TLB:38:37:35:31.32.33,20:29:31.38.32:36.34.35,THB:38:32:29.37.36:35,33:32:29:36.34.35,33:34:29:31.38.32,20:29:35:31.32.33,(27.35,-8.32,;27.35,-9.86,;28.68,-10.63,;30.01,-9.86,;31.35,-10.63,;31.35,-12.18,;30.01,-12.95,;28.68,-12.18,;27.35,-12.94,;25.95,-12.32,;24.92,-13.46,;25.69,-14.79,;25.06,-16.2,;27.19,-14.48,;32.67,-9.85,;34.08,-10.47,;35.11,-9.33,;36.65,-9.35,;37.44,-8.03,;36.69,-6.68,;38.98,-8.06,;39.77,-6.74,;39.02,-5.39,;39.82,-4.08,;39.08,-2.73,;37.53,-2.71,;36.78,-1.36,;36.74,-4.04,;37.49,-5.38,;39.73,-9.4,;40.92,-8.13,;42.25,-8.61,;43.65,-8.26,;43.66,-6.73,;42.26,-6.16,;40.92,-6.63,;41.22,-7.39,;41.23,-8.98,;42.63,-9.54,;34.33,-8,;32.83,-8.32,)|	InChI=1S/C32H35FN6O2/c1-20-15-37(19-34-20)29-8-5-24(14-30(29)41-2)28-17-38(36-35-28)18-31(40)39(16-21-3-6-27(33)7-4-21)32-25-10-22-9-23(12-25)13-26(32)11-22/h3-8,14-15,17,19,22-23,25-26,32H,9-13,16,18H2,1-2H3	SXAROQNHORDUFM-UHFFFAOYSA-N	50381445	CHEMBL2017413	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 250							ChEMBL	10.1016/j.bmcl.2012.03.054	10.7270/Q24Q7W0H	22497762			Fischer, C; Zultanski, SL; Zhou, H; Methot, JL; Shah, S; Nuthall, H; Hughes, BL; Smotrov, N; Hill, A; Szewczak, AA; Moxham, CM; Bays, N; Middleton, RE; Munoz, B; Shearman, MS	4/20/2012	2/7/2013	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381445	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381445&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70693785	160860528		CHEMBL2017413					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50930085	COc1cc(ccc1-n1cnc(C)c1)-c1cn(nn1)[C@H]1C[C@H](CCN(CC23CC4CC(CC(C4)C2)C3)C1=O)C(C)(C)C |r,TLB:25:26:29:33.31.32,THB:31:30:27:33.32.34,31:32:29.30.35:27,34:32:29:35.26.27,34:26:29:33.31.32|	InChI=1S/C34H46N6O2/c1-22-18-39(21-35-22)29-7-6-26(13-31(29)42-5)28-19-40(37-36-28)30-14-27(33(2,3)4)8-9-38(32(30)41)20-34-15-23-10-24(16-34)12-25(11-23)17-34/h6-7,13,18-19,21,23-25,27,30H,8-12,14-17,20H2,1-5H3	DHUDBVNXSIDYGA-UHFFFAOYSA-N	50381464	CHEMBL2017576	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 870							ChEMBL	10.1016/j.bmcl.2012.03.054	10.7270/Q24Q7W0H	22497762			Fischer, C; Zultanski, SL; Zhou, H; Methot, JL; Shah, S; Nuthall, H; Hughes, BL; Smotrov, N; Hill, A; Szewczak, AA; Moxham, CM; Bays, N; Middleton, RE; Munoz, B; Shearman, MS	4/20/2012	2/7/2013	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381464	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381464&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			70693791	160860547		CHEMBL2017576					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50949864	C1CN2CCC1C(C2)c1nc(no1)-c1ccc(o1)-c1cccnc1 |THB:8:6:1.0:3.4,(29.34,1.99,;29.39,3.56,;30.7,2.53,;29.94,.55,;30.14,-.76,;30.63,.99,;32.38,1.3,;32.52,2.84,;33.52,.26,;35.03,.57,;35.79,-.77,;34.75,-1.91,;33.34,-1.27,;37.32,-.94,;38.08,-2.28,;39.58,-1.98,;39.76,-.45,;38.36,.19,;41.1,.31,;42.42,-.47,;43.76,.29,;43.78,1.83,;42.44,2.61,;41.11,1.85,)|	InChI=1S/C18H18N4O2/c1-2-13(10-19-7-1)15-3-4-16(23-15)17-20-18(24-21-17)14-11-22-8-5-12(14)6-9-22/h1-4,7,10,12,14H,5-6,8-9,11H2	HAFBPVOPBRQKOM-UHFFFAOYSA-N	50389668	CHEMBL2069928	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 6400							ChEMBL	10.1021/jm2013248	10.7270/Q2XK8GMR	22185670			Bostrom, J; Hogner, A; Llinas, A; Wellner, E; Plowright, AT	3/8/2012	2/8/2013	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50389668	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50389668&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11645473	160868751		CHEMBL2069928					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50949865	C1CN2CCC1C(C2)c1nnc(o1)-c1ccc(o1)-c1cccnc1 |THB:8:6:1.0:3.4,(-8.86,-9.77,;-8.8,-8.2,;-7.49,-9.23,;-8.25,-11.21,;-8.05,-12.51,;-7.56,-10.77,;-5.81,-10.45,;-5.67,-8.92,;-4.68,-11.49,;-4.85,-13.02,;-3.45,-13.66,;-2.41,-12.53,;-3.17,-11.19,;-.88,-12.7,;-.12,-14.04,;1.39,-13.73,;1.56,-12.2,;.16,-11.56,;2.9,-11.44,;4.23,-12.23,;5.57,-11.47,;5.58,-9.93,;4.25,-9.15,;2.91,-9.91,)|	InChI=1S/C18H18N4O2/c1-2-13(10-19-7-1)15-3-4-16(23-15)18-21-20-17(24-18)14-11-22-8-5-12(14)6-9-22/h1-4,7,10,12,14H,5-6,8-9,11H2	UJAGUKYONYCFSM-UHFFFAOYSA-N	50389669	CHEMBL2069929	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 20200							ChEMBL	10.1021/jm2013248	10.7270/Q2XK8GMR	22185670			Bostrom, J; Hogner, A; Llinas, A; Wellner, E; Plowright, AT	3/8/2012	2/8/2013	Astrazeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50389669	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50389669&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			11508058	160868752		CHEMBL2069929					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
50997487	C(Cc1ccccc1)N1[C@H]2CC[C@@H]1CC(C2)c1c([nH]c2ccccc12)-c1ccccc1 |THB:0:8:14.15.13:11.10|	InChI=1S/C29H30N2/c1-3-9-21(10-4-1)17-18-31-24-15-16-25(31)20-23(19-24)28-26-13-7-8-14-27(26)30-29(28)22-11-5-2-6-12-22/h1-14,23-25,30H,15-20H2	QOUVFTQPYVSKEQ-UHFFFAOYSA-N	50409215	CHEMBL2113667	Potassium voltage-gated channel subfamily H member 2	Homo sapiens	 18								ChEMBL	10.1021/jm0004998	10.7270/Q27M076K	11334570			Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM	5/3/2001	11/10/2009	Merck Sharp and Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409215	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409215&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71458069	163358239		CHEMBL2113667					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51006495	OC1CN2C3CC(CC2CC1C3)OC(=O)c1c[nH]c2ccccc12 |THB:5:4:1.2:8.9,7:8:1.2:11.4,0:1:11.4:8.9|	InChI=1S/C19H22N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,18,20,22H,5-8,10H2	MLWGAEVSWJXOQJ-UHFFFAOYSA-N	50412171	Mdl 74156::MDL-74156	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 5888.44							ChEMBL	10.1016/j.bmc.2008.04.028	10.7270/Q25D8T25	18448342			Jia, L; Sun, H	6/5/2008	5/21/2013	F. Hoffmann-La Roche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412171	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412171&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			159502	163361195							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51010029	COC(=O)C1=CC[C@@H]2CC[C@H]1N2C |r,t:4,TLB:12:11:9.8:4.5.6,THB:2:4:9.8:11|	InChI=1S/C10H15NO2/c1-11-7-3-5-8(10(12)13-2)9(11)6-4-7/h5,7,9H,3-4,6H2,1-2H3	MPSNEAHFGOEKBI-UHFFFAOYSA-N	50413637	METHYLECGONIDINE	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 169824.37							ChEMBL	10.1016/j.ejmech.2007.12.025	10.7270/Q2542PTB	18262683			Coi, A; Massarelli, I; Testai, L; Calderone, V; Bianucci, AM	10/28/2008	5/21/2013	University of Pisa	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50413637	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50413637&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			119478	163362661							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51018570	Cc1ncoc1-c1nnc(SCCCN2[C@H]3CC[C@@H]2C[C@@H](C3)c2ccc(cc2F)C(F)(F)F)n1C |r,TLB:13:14:16.17:21.20.19,THB:22:20:16.17:14|	InChI=1S/C24H27F4N5OS/c1-14-21(34-13-29-14)22-30-31-23(32(22)2)35-9-3-8-33-17-5-6-18(33)11-15(10-17)19-7-4-16(12-20(19)25)24(26,27)28/h4,7,12-13,15,17-18H,3,5-6,8-11H2,1-2H3	NWCMUBVTFZOFKO-UHFFFAOYSA-N	50417124	CHEMBL1257448	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 501.19							ChEMBL	10.1021/jm100832d	10.7270/Q2CJ8DQZ	20839775			Micheli, F; Arista, L; Bertani, B; Braggio, S; Capelli, AM; Cremonesi, S; Di-Fabio, R; Gelardi, G; Gentile, G; Marchioro, C; Pasquarello, A; Provera, S; Tedesco, G; Tarsi, L; Terreni, S; Worby, A; Heidbreder, C	10/7/2010	6/13/2011	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417124	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417124&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			49781478	163366148		CHEMBL1257448					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51018580	Cc1ncoc1-c1nnc(SCCCN2[C@H]3CC[C@@H]2C[C@@H](C3)c2cccc(c2)C(F)(F)F)n1C |r,TLB:13:14:16.17:21.20.19,THB:22:20:16.17:14|	InChI=1S/C24H28F3N5OS/c1-15-21(33-14-28-15)22-29-30-23(31(22)2)34-10-4-9-32-19-7-8-20(32)13-17(12-19)16-5-3-6-18(11-16)24(25,26)27/h3,5-6,11,14,17,19-20H,4,7-10,12-13H2,1-2H3	QSDLVBSOCJOFJV-UHFFFAOYSA-N	50417132	CHEMBL1257337	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 501.19							ChEMBL	10.1021/jm100832d	10.7270/Q2CJ8DQZ	20839775			Micheli, F; Arista, L; Bertani, B; Braggio, S; Capelli, AM; Cremonesi, S; Di-Fabio, R; Gelardi, G; Gentile, G; Marchioro, C; Pasquarello, A; Provera, S; Tedesco, G; Tarsi, L; Terreni, S; Worby, A; Heidbreder, C	10/7/2010	6/13/2011	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417132	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417132&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			49781477	163366156		CHEMBL1257337					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51049093	CCOC(=O)N1[C@H]2CC[C@@H]1C[C@@H](CN1CC[C@@H](C1)N1C(=O)Cc3ccccc13)C2 |r,THB:3:5:11.28.10:7.8|	InChI=1S/C23H31N3O3/c1-2-29-23(28)25-18-7-8-19(25)12-16(11-18)14-24-10-9-20(15-24)26-21-6-4-3-5-17(21)13-22(26)27/h3-6,16,18-20H,2,7-15H2,1H3	PNUNTGVSYVVWCT-UHFFFAOYSA-N	50428138	CHEMBL2336059	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 2400							ChEMBL	10.1021/ml300372f	10.7270/Q20Z74N3	24900656			Sumiyoshi, T; Enomoto, T; Takai, K; Takahashi, Y; Konishi, Y; Uruno, Y; Tojo, K; Suwa, A; Matsuda, H; Nakako, T; Sakai, M; Kitamura, A; Uematsu, Y; Kiyoshi, A	2/14/2013	9/24/2013	Dainippon Sumitomo Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50428138	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50428138&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			71719475	164157013		CHEMBL2336059					1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51131857	[H][C@]12CC[C@]([H])(C[C@H](C1)OCCCc1ccc(cc1)S(=O)(=O)Nc1c(CC(C)C)ccc3nn(C)cc13)N2C |r,THB:38:37:7.6.8:3.2|	InChI=1S/C29H40N4O3S/c1-20(2)16-22-9-14-28-27(19-32(3)30-28)29(22)31-37(34,35)26-12-7-21(8-13-26)6-5-15-36-25-17-23-10-11-24(18-25)33(23)4/h7-9,12-14,19-20,23-25,31H,5-6,10-11,15-18H2,1-4H3	FUPLMCDALVVROC-UHFFFAOYSA-N	50464049	CHEMBL4243933	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		 3300							ChEMBL	10.1021/acs.jmedchem.8b00884	10.7270/Q28K7CR1	30207721			Harrison, JR; Brand, S; Smith, V; Robinson, DA; Thompson, S; Smith, A; Davies, K; Mok, N; Torrie, LS; Collie, I; Hallyburton, I; Norval, S; Simeons, FRC; Stojanovski, L; Frearson, JA; Brenk, R; Wyatt, PG; Gilbert, IH; Read, KD	9/27/2018	8/17/2020	University of Dundee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50464049	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50464049&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			145983060	433931314							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51420935	[H][C@@]12Cc3c(COC(=O)\C=C\c4ccccc4)cc(OC)c(OC(=O)\C=C\c4ccccc4)c3[C@]3(CCN1C)CC(=O)C(OC)=C[C@]23[H] |r,c:48,THB:38:37:3.33.2:46|	InChI=1S/C38H37NO7/c1-39-19-18-38-23-31(40)32(43-2)22-29(38)30(39)21-28-27(24-45-34(41)16-14-25-10-6-4-7-11-25)20-33(44-3)37(36(28)38)46-35(42)17-15-26-12-8-5-9-13-26/h4-17,20,22,29-30H,18-19,21,23-24H2,1-3H3	FWYDJCQVRKENER-UHFFFAOYSA-N	50573990	CHEMBL4859823	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							ChEMBL	10.1016/j.ejmech.2021.113791	10.7270/Q2FF3X5P	34450495			Zhang, Z; Wang, H; Yuan, J; Li, X; Fang, N; Lin, M; Hou, Q; Ji, T	12/5/2021	8/23/2022	Peking Union Medical College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50573990	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50573990&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			164610975	471064135							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51476960	Fc1ccc(-c2c[nH]c(c2)C(=O)NC2C3CC4CC(C3)CC2C4)c(F)n1 |TLB:22:21:15.16.17:19,THB:17:16:13:18.20.19,17:18:13:15.16.22,22:16:21.13.20:19,12:13:15.16.17:19,(-4.37,7,;-3.83,5.57,;-4.8,4.38,;-4.26,2.95,;-2.75,2.69,;-2.22,1.26,;-3.06,-.02,;-2.11,-1.22,;-.67,-.69,;-.74,.85,;.61,-1.53,;1.98,-.85,;.51,-3.06,;1.79,-3.91,;3.24,-3.36,;2.15,-4.72,;2.21,-6.44,;3.75,-7,;4.8,-5.59,;4.77,-3.93,;3.3,-6.01,;1.85,-5.53,;.59,-6.95,;-1.77,3.88,;-.26,3.63,;-2.31,5.33,)|	InChI=1S/C20H21F2N3O/c21-17-2-1-15(19(22)24-17)14-8-16(23-9-14)20(26)25-18-12-4-10-3-11(6-12)7-13(18)5-10/h1-2,8-13,18,23H,3-7H2,(H,25,26)	DWGDVELBEXGGDR-UHFFFAOYSA-N	50595430	CHEMBL5178543	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							ChEMBL		10.7270/Q2PV6QCB	35915958			Zhao, H; Gao, Y; Li, W; Sheng, L; Cui, K; Wang, B; Fu, L; Gao, M; Lin, Z; Zou, X; Jackson, M; Huang, H; Lu, Y; Zhang, D	8/11/2022	6/21/2023	Peking Union Medical College and Chinese Academy of Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595430	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595430&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137545401	482606282							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51476961	Fc1ccc(-c2c[nH]c(c2)C(=O)NC23CC4CC(CC(C4)C2)C3)c(F)c1 |TLB:12:13:16.15.20:18,THB:21:13:16:20.19.18,21:19:16:13.22.14,14:13:16.15.20:18,14:15:13.22.21:18,12:13:16:20.19.18|	InChI=1S/C21H22F2N2O/c22-16-1-2-17(18(23)7-16)15-6-19(24-11-15)20(26)25-21-8-12-3-13(9-21)5-14(4-12)10-21/h1-2,6-7,11-14,24H,3-5,8-10H2,(H,25,26)	BBPDUFJGRKNUNQ-UHFFFAOYSA-N	50595431	CHEMBL5183816	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							ChEMBL		10.7270/Q2PV6QCB	35915958			Zhao, H; Gao, Y; Li, W; Sheng, L; Cui, K; Wang, B; Fu, L; Gao, M; Lin, Z; Zou, X; Jackson, M; Huang, H; Lu, Y; Zhang, D	8/11/2022	6/21/2023	Peking Union Medical College and Chinese Academy of Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595431	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595431&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137545489	482606283							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51476962	Fc1ccc(-c2c[nH]c(c2)C(=O)NC23CC4CC(CC(C4)C2)C3)c(F)n1 |TLB:12:13:16.15.20:18,THB:21:13:16:20.19.18,21:19:16:13.22.14,14:13:16.15.20:18,14:15:13.22.21:18,12:13:16:20.19.18|	InChI=1S/C20H21F2N3O/c21-17-2-1-15(18(22)24-17)14-6-16(23-10-14)19(26)25-20-7-11-3-12(8-20)5-13(4-11)9-20/h1-2,6,10-13,23H,3-5,7-9H2,(H,25,26)	INQHPSZNWXCBFL-UHFFFAOYSA-N	50595432	CHEMBL5208906	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							ChEMBL		10.7270/Q2PV6QCB	35915958			Zhao, H; Gao, Y; Li, W; Sheng, L; Cui, K; Wang, B; Fu, L; Gao, M; Lin, Z; Zou, X; Jackson, M; Huang, H; Lu, Y; Zhang, D	8/11/2022	6/21/2023	Peking Union Medical College and Chinese Academy of Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595432	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595432&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			137545440	482606284							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																														
51482405	CC(C)n1nccc1C(=O)N[C@@H](C(C1CC1)C1CC1)C(=O)Nc1ccc(cc1)-c1c(C)n[nH]c1C |r|	InChI=1S/C27H34N6O2/c1-15(2)33-22(13-14-28-33)26(34)30-25(24(19-5-6-19)20-7-8-20)27(35)29-21-11-9-18(10-12-21)23-16(3)31-32-17(23)4/h9-15,19-20,24-25H,5-8H2,1-4H3,(H,29,35)(H,30,34)(H,31,32)	CQKVACARDGYEMU-UHFFFAOYSA-N	50597429	CHEMBL5194116	Potassium voltage-gated channel subfamily H member 2	Homo sapiens		>30000							ChEMBL		10.7270/Q22B9327	35767390			Andrews, MD; Dack, KN; de Groot, MJ; Lambert, M; Sennbro, CJ; Larsen, M; Stahlhut, M	7/14/2022	6/22/2023	Leo Pharma Research & Early Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50597429	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2132&target=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50597429&enzyme=Potassium+voltage-gated+channel+subfamily+H+member+2&column=ki&startPg=0&Increment=50&submit=Search			153616520	482608281							1	MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS	8IOB,8IO5,8IO4,5VA2,8ZYQ,8ZYP,8ZYO,8ZYN,7CN1,7CN0,5VA1,9CHS,9CHR,9CHQ,9CHP,5VA3,2L4R,4HQA,2L0W,6SYG,2N7G	Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2_HUMAN	Q12809	A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0		Voltage-gated inwardly rectifying potassium channel KCNH2	A0A090N8Q0_HUMAN	A0A090N8Q0